Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50022659
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416877BDBM50416877(CHEMBL6103265)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416878BDBM50416878(CHEMBL6078192)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412982BDBM50412982(CHEMBL6102102)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416874BDBM50416874(CHEMBL6102935)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412977BDBM50412977(CHEMBL6074553)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412980BDBM50412980(CHEMBL6078335)
Affinity DataIC50: 15nMAssay Description:Inverse agonist activity at RORgammaT (unknown origin) by Jurkat cell based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416879BDBM50416879(CHEMBL6082902)
Affinity DataIC50: 15nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412978BDBM50412978(CHEMBL6102989)
Affinity DataIC50: 20nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412981BDBM50412981(CHEMBL6082896)
Affinity DataIC50: 24nMAssay Description:Inhibition of human ERG by whole cell based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 535532BDBM535532(N-(2-(4,4-Difluoropiperidin-1-yl)-6- methylpyrimid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416876BDBM50416876(CHEMBL6078180)
Affinity DataIC50: 43nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412979BDBM50412979(CHEMBL6078170)
Affinity DataIC50: 54nMAssay Description:Inverse agonist activity at RORgammaT (unknown origin) by Jurkat cell based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412976BDBM50412976(CHEMBL5077455)
Affinity DataIC50: 62nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 535533BDBM535533((R)-N-(2-(4,4-Difluoropiperidin-1-yl)- 6-methylpyr...)
Affinity DataIC50: 71nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404038BDBM50404038(CHEMBL1990168)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412977BDBM50412977(CHEMBL6074553)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed