Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50022842
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 367828BDBM367828(US10227331, Example 15 | 3-(2-Amino-7-methyl-1H-be...)
Affinity DataIC50: 0.0400nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654955BDBM50654955(CHEMBL6142940)
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368126BDBM368126(3-(2-aminobenzo[d]thiazol-4-yl)-6-((2-aminoethyl)s...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 367819BDBM367819(US10227331, Example 6 | 4-(Azetidin-3-ylsulfonyl)-...)
Affinity DataIC50: 0.310nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368135BDBM368135(4-((2-aminoethyl)sulfonyl)-4′-(piperidin-4-y...)
Affinity DataIC50: 0.730nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 262417BDBM262417(US9708336, 269)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368041BDBM368041(US10227331, Example 228 | 4′-(piperidin-4-yl...)
Affinity DataIC50: 0.990nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654954BDBM50654954(CHEMBL5891081)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368049BDBM368049(US10227331, Example 236 | 4-(methylsulfonyl)-4R...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654953BDBM50654953(CHEMBL5284444)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 262182BDBM262182(US9708336, 31 | 4′-piperidin-4-yl-2-(1H-tetr...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 262604BDBM262604(4′-(piperidin-4-yl)-4-(piperidin-4-ylmethyl)...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 368039BDBM368039(US10227331, Example 226 | 4′-(piperidin-4-yl...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed