Report error Found 138 Enz. Inhib. hit(s) with all data for entry = 50023386
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.40nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 6.70nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.40nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.5nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 12nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 16nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 18nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 21nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 25nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged full length recombinant human HDAC6 (1 to 1215 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-AMC as ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 34nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 35nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 37nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 42nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 42nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 44nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 46nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 58nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 62nMAssay Description:Binding affinity to HDAC2 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 65nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 65nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 66nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 69nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Binding affinity to HDAC2 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 73nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 93nMAssay Description:Inhibition of C-terminal 6-his/FLAG tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in sf9 cells using ZMAL (Z-Lys(Ac)-A...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of C-terminal His tagged human recombinant HDAC3 (1 to 428 end residues)/N-terminal GST-tagged human NcoR2 expressed in sf9 cells using ZM...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 100nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Binding affinity to HDAC2 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 103nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Binding affinity to HDAC2 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 108nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Binding affinity to HDAC2 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 110nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Binding affinity to HDAC1 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Binding affinity to HDAC3 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair








3D Structure (crystal)