Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50023475
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 0.720nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Genentech Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetMisshapen-like kinase 1(Human)
Genentech Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataEC50:  6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591137BDBM591137(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7- f...)
Affinity DataEC50:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591138BDBM591138(US11566003, Compound 230 | US11566003, Compound 23...)
Affinity DataEC50:  20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598027BDBM598027(US11612606, Compound 401 | Tetrahydro-2H-pyran-4-y...)
Affinity DataEC50:  39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetAurora kinase B(Human)
Genentech Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591138BDBM591138(US11566003, Compound 230 | US11566003, Compound 23...)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598027BDBM598027(US11612606, Compound 401 | Tetrahydro-2H-pyran-4-y...)
Affinity DataIC50: 97nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591137BDBM591137(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7- f...)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50664063BDBM50664063(CHEMBL6172131)
Affinity DataEC50:  186nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591148BDBM591148(tetrahydro-2H-pyran-4-yl (8-amino- 6-(5-amino-4-me...)
Affinity DataEC50:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50664063BDBM50664063(CHEMBL6172131)
Affinity DataIC50: 280nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591102BDBM591102((2R)-2-(4-(8-amino-7-fluoro-6-(4-methylpyridin-3-y...)
Affinity DataEC50:  419nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591102BDBM591102((2R)-2-(4-(8-amino-7-fluoro-6-(4-methylpyridin-3-y...)
Affinity DataIC50: 570nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 591148BDBM591148(tetrahydro-2H-pyran-4-yl (8-amino- 6-(5-amino-4-me...)
Affinity DataIC50: 620nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Genentech Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 598085BDBM598085(US11612606, Compound 441c | (cis)-4-Methyltetrahyd...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed