Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50022691
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 1nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 3nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653131BDBM50653131(CHEMBL6078446)
Affinity DataIC50: 136nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653133BDBM50653133(CHEMBL6120517)
Affinity DataIC50: 161nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653131BDBM50653131(CHEMBL6078446)
Affinity DataIC50: 161nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653134BDBM50653134(CHEMBL6102514)
Affinity DataIC50: 180nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653134BDBM50653134(CHEMBL6102514)
Affinity DataIC50: 220nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653133BDBM50653133(CHEMBL6120517)
Affinity DataIC50: 251nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 298nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 312nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653132BDBM50653132(CHEMBL6142306)
Affinity DataIC50: 321nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653132BDBM50653132(CHEMBL6142306)
Affinity DataIC50: 378nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653135BDBM50653135(CHEMBL6101817)
Affinity DataIC50: 1.00E+6nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653135BDBM50653135(CHEMBL6101817)
Affinity DataIC50: 1.00E+6nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed