Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50021901
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20461BDBM20461(Zostrix | (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl...)
Affinity DataEC50:  200nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314522BDBM50314522(CHEMBL6120395)
Affinity DataEC50:  300nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331216BDBM50331216(CHEMBL6078061)
Affinity DataEC50:  400nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314519BDBM50314519(CHEMBL6091959)
Affinity DataEC50:  500nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331227BDBM50331227(CHEMBL6077995)
Affinity DataEC50:  700nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314521BDBM50314521(CHEMBL6091896)
Affinity DataEC50:  700nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314520BDBM50314520(CHEMBL6102233)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20461BDBM20461(Zostrix | (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331225BDBM50331225(CHEMBL6082866)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331213BDBM50331213(CHEMBL6082929)
Affinity DataEC50:  1.90E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331214BDBM50331214(CHEMBL6078161)
Affinity DataEC50:  2.10E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331222BDBM50331222(CHEMBL6133468)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331226BDBM50331226(CHEMBL6078405)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314518BDBM50314518(CHEMBL6132834)
Affinity DataEC50:  3.10E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316789BDBM50316789(CHEMBL6102183)
Affinity DataEC50:  3.70E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331220BDBM50331220(CHEMBL6102217)
Affinity DataEC50:  4.70E+3nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells by cell-based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314517BDBM50314517(CHEMBL6083159)
Affinity DataEC50:  5.20E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314524BDBM50314524(CHEMBL6078003)
Affinity DataEC50:  7.40E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358188BDBM50358188(CHEMBL6082939)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331224BDBM50331224(CHEMBL6083024)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314516BDBM50314516(CHEMBL6083053)
Affinity DataEC50:  1.06E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331218BDBM50331218(CHEMBL6074505)
Affinity DataEC50:  1.14E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331230BDBM50331230(CHEMBL6103240)
Affinity DataEC50:  1.34E+4nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314523BDBM50314523(CHEMBL6101993)
Affinity DataEC50:  1.35E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331219BDBM50331219(CHEMBL6074535)
Affinity DataEC50:  1.52E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331228BDBM50331228(CHEMBL6103010)
Affinity DataEC50:  2.03E+4nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331221BDBM50331221(CHEMBL6120741)
Affinity DataEC50:  2.18E+4nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells by cell-based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331217BDBM50331217(CHEMBL6134205)
Affinity DataEC50:  2.33E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331215BDBM50331215(CHEMBL6082912)
Affinity DataEC50:  2.68E+4nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331229BDBM50331229(CHEMBL6078168)
Affinity DataEC50:  3.31E+4nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331223BDBM50331223(CHEMBL6082942)
Affinity DataEC50:  3.64E+4nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331215BDBM50331215(CHEMBL6082912)
Affinity DataEC50:  4.75E+4nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345805BDBM50345805(CHEMBL6082957)
Affinity DataIC50: 5.42E+4nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345806BDBM50345806(CHEMBL6102422)
Affinity DataIC50: 6.49E+4nMAssay Description:Inhibition of MRP1 expressed in human 2008 cells assessed as calcein AM accumulation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358190BDBM50358190(CHEMBL6078088)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339815BDBM50339815(CHEMBL6078143)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339814BDBM50339814(CHEMBL450812)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345809BDBM50345809(CHEMBL6082925)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345808BDBM50345808(CHEMBL6083026)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MRP1 expressed in human 2008 cells assessed as calcein AM accumulation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358189BDBM50358189(CHEMBL6078390)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331231BDBM50331231(CHEMBL6101863)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341205BDBM50341205(CHEMBL6108960)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Universidad Miguel Hernandez

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345807BDBM50345807(CHEMBL6074478)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MRP1 expressed in human 2008 cells assessed as calcein AM accumulation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed