Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 50022749
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 1nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300690BDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300690BDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300690BDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653855BDBM50653855(CHEMBL6147413)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653850BDBM50653850(CHEMBL6134348)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653850BDBM50653850(CHEMBL6134348)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653835BDBM50653835(CHEMBL6102458)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653851BDBM50653851(CHEMBL6091975)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653858BDBM50653858(CHEMBL6091760)
Affinity DataIC50: 13nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653841BDBM50653841(CHEMBL6103270)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CSF1R by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653843BDBM50653843(CHEMBL6092100)
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653856BDBM50653856(CHEMBL6108944)
Affinity DataIC50: 16nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653838BDBM50653838(CHEMBL6134212)
Affinity DataIC50: 19nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653862BDBM50653862(CHEMBL6120791)
Affinity DataIC50: 28nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653851BDBM50653851(CHEMBL6091975)
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653836BDBM50653836(CHEMBL6120830)
Affinity DataIC50: 28nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653857BDBM50653857(CHEMBL6120567)
Affinity DataIC50: 30nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653837BDBM50653837(CHEMBL6160022)
Affinity DataIC50: 37nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653852BDBM50653852(CHEMBL6151537)
Affinity DataIC50: 47nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 55nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653865BDBM50653865(CHEMBL6145200)
Affinity DataIC50: 66nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653857BDBM50653857(CHEMBL6120567)
Affinity DataIC50: 73nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653880BDBM50653880(CHEMBL6120876)
Affinity DataIC50: 103nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653863BDBM50653863(CHEMBL6141907)
Affinity DataIC50: 127nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653845BDBM50653845(CHEMBL6120322)
Affinity DataIC50: 138nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653848BDBM50653848(CHEMBL6102094)
Affinity DataIC50: 163nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653844BDBM50653844(CHEMBL6133979)
Affinity DataIC50: 175nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653835BDBM50653835(CHEMBL6102458)
Affinity DataIC50: 211nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653831BDBM50653831(CHEMBL6144437)
Affinity DataIC50: 252nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653834BDBM50653834(CHEMBL6133642)
Affinity DataIC50: 262nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653860BDBM50653860(CHEMBL6144112)
Affinity DataIC50: 262nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653839BDBM50653839(CHEMBL6142209)
Affinity DataIC50: 300nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653870BDBM50653870(CHEMBL6132749)
Affinity DataIC50: 327nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653834BDBM50653834(CHEMBL6133642)
Affinity DataIC50: 343nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653847BDBM50653847(CHEMBL6145443)
Affinity DataIC50: 408nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653841BDBM50653841(CHEMBL6103270)
Affinity DataIC50: 488nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653846BDBM50653846(CHEMBL6161236)
Affinity DataIC50: 508nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653853BDBM50653853(CHEMBL6133148)
Affinity DataIC50: 520nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653861BDBM50653861(CHEMBL6145209)
Affinity DataIC50: 581nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653849BDBM50653849(CHEMBL6159656)
Affinity DataIC50: 680nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653862BDBM50653862(CHEMBL6120791)
Affinity DataIC50: 815nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653865BDBM50653865(CHEMBL6145200)
Affinity DataIC50: 894nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653840BDBM50653840(CHEMBL6092081)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653842BDBM50653842(CHEMBL6148006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653873BDBM50653873(CHEMBL6102487)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
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