Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50022684
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602064BDBM50602064(CHEMBL6102833)
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602065BDBM50602065(CHEMBL6147386)
Affinity DataIC50: 43nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596398BDBM50596398(CHEMBL6146733)
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592544BDBM50592544(CHEMBL6103030)
Affinity DataIC50: 360nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 460nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602066BDBM50602066(CHEMBL6133897)
Affinity DataIC50: 890nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596397BDBM50596397(CHEMBL6141701)
Affinity DataIC50: 1.47E+3nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592543BDBM50592543(CHEMBL6101994)
Affinity DataIC50: 1.81E+3nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605863BDBM50605863(CHEMBL6134432)
Affinity DataIC50: 3.67E+3nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602063BDBM50602063(CHEMBL6150315)
Affinity DataIC50: 4.81E+3nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596399BDBM50596399(CHEMBL6142898)
Affinity DataIC50: 6.55E+3nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602067BDBM50602067(CHEMBL6146389)
Affinity DataIC50: 1.54E+4nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602064BDBM50602064(CHEMBL6102833)
Affinity DataIC50: 2.50E+4nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633832BDBM50633832(CHEMBL6102988)
Affinity DataIC50: 2.50E+4nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592542BDBM50592542(CHEMBL6102442)
Affinity DataIC50: 2.50E+4nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592541BDBM50592541(CHEMBL6142409)
Affinity DataIC50: 2.50E+4nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed