Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50022817
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654579BDBM50654579(CHEMBL6152207)
Affinity DataKd:  1nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654575BDBM50654575(CHEMBL6149653)
Affinity DataKd:  13nMAssay Description:Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654576BDBM50654576(CHEMBL6144367)
Affinity DataKd:  27nMAssay Description:Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654570BDBM50654570(CHEMBL6120704)
Affinity DataKd:  28nMAssay Description:Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654573BDBM50654573(CHEMBL5202030)
Affinity DataKd:  45nMAssay Description:Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654577BDBM50654577(CHEMBL6149638)
Affinity DataKd:  59nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654574BDBM50654574(CHEMBL6148822)
Affinity DataKd:  86nMAssay Description:Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654572BDBM50654572(CHEMBL6143397)
Affinity DataKd:  117nMAssay Description:Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654571BDBM50654571(CHEMBL6134410)
Affinity DataKd:  170nMAssay Description:Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654569BDBM50654569(CHEMBL6103116)
Affinity DataKd:  374nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 42) production by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654578BDBM50654578(CHEMBL6091807)
Affinity DataKd:  506nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 40) production by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654569BDBM50654569(CHEMBL6103116)
Affinity DataKd:  548nMAssay Description:Agonist activity at human PPARalpha assessed as induction of transactivation activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed