Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50016096
LigandChemical structure of BindingDB Monomer ID 50192880BDBM50192880(CHEMBL3984425 | US9775844, Compound 4 | US10329299...)
Affinity DataKd:  0.290nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50436459BDBM50436459(CHEMBL2396661)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50192880BDBM50192880(CHEMBL3984425 | US9775844, Compound 4 | US10329299...)
Affinity DataKd:  17nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50192880BDBM50192880(CHEMBL3984425 | US9775844, Compound 4 | US10329299...)
Affinity DataKd:  82nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 210nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50436459BDBM50436459(CHEMBL2396661)
Affinity DataIC50: 250nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50436459BDBM50436459(CHEMBL2396661)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed