Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50022747
TargetSerine/threonine-protein kinase PLK1(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653819BDBM50653819(CHEMBL6096576)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50585402BDBM50585402(CHEMBL5081048)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653817BDBM50653817(CHEMBL6134128)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653816BDBM50653816(CHEMBL6134139)
Affinity DataIC50: 5nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKRas/Son of Sevenless Homolog 1(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581659BDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50: 5nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579985BDBM50579985(Jdq 443 | Jdq-443 | Nvp-jdq-443 | JDQ443 | JDQ-443...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKRas/Son of Sevenless Homolog 1(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614629BDBM50614629(BAY-293)
Affinity DataIC50: 21nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520327BDBM50520327(CHEMBL4456044)
Affinity DataKd:  51nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKRas/Son of Sevenless Homolog 1(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549225BDBM50549225(CHEMBL4750445 | US12281099, Example I-093)
Affinity DataIC50: 450nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549225BDBM50549225(CHEMBL4750445 | US12281099, Example I-093)
Affinity DataKd:  750nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653818BDBM50653818(CHEMBL4751908)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503649BDBM50503649(CHEMBL4476113)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514402BDBM50514402(CHEMBL4535757 | US11345701, Compound Amg-510)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed