Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010482
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253992BDBM50253992(CHEMBL6074469)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253991BDBM50253991(CHEMBL6082944)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253990BDBM50253990(CHEMBL6078562)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15579BDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataIC50: 84nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32020BDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 97nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253990BDBM50253990(CHEMBL6078562)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253990BDBM50253990(CHEMBL6078562)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253990BDBM50253990(CHEMBL6078562)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29136BDBM29136(Iprazid | Euphozid | CHEMBL92401 | Iproniazid)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29136BDBM29136(Iprazid | Euphozid | CHEMBL92401 | Iproniazid)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15579BDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15613BDBM15613(MCL | Aurorix | 4-chloro-N-[2-(morpholin-4-yl)ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Instituto de Quimica Midica (IQM-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15613BDBM15613(MCL | Aurorix | 4-chloro-N-[2-(morpholin-4-yl)ethy...)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed