Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50023445
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050549BDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663825BDBM50663825(CHEMBL6168808)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663824BDBM50663824(CHEMBL6152473)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663823BDBM50663823(CHEMBL6161976)
Affinity DataIC50: 44nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663825BDBM50663825(CHEMBL6168808)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050549BDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 900nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663823BDBM50663823(CHEMBL6161976)
Affinity DataIC50: 900nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663824BDBM50663824(CHEMBL6152473)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed