Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50005593
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50483742BDBM50483742(CHEMBL1770898)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50458159BDBM50458159(Nirogacestat | PF 03084014 | PF 3084014 | PF-03084...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A adrenergic receptor(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 160475BDBM160475(US9682968, Example-26a | US10093663, Example 26b |...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637405BDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50478375BDBM50478375(CHEBI:86193 | CHEMBL255682)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637405BDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637405BDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor after 120 mins by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed