Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50022806
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654465BDBM50654465(CHEMBL6141890)
Affinity DataIC50: 6nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654459BDBM50654459(CHEMBL6102400)
Affinity DataKd:  8.5nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) assessed as reduction in E2 induced response after 24 hrs by cell based ERE-driven lucife...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654467BDBM50654467(CHEMBL6091911)
Affinity DataIC50: 13nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654471BDBM50654471(CHEMBL6142475)
Affinity DataIC50: 15nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654458BDBM50654458(CHEMBL6091951)
Affinity DataKd:  16nMAssay Description:Antagonist activity at full length ERbeta (unknown origin) assessed as reduction in E2 induced response after 24 hrs by cell based ERE-driven lucifer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654473BDBM50654473(CHEMBL6143218)
Affinity DataIC50: 21nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654468BDBM50654468(CHEMBL6133443)
Affinity DataIC50: 22nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654461BDBM50654461(CHEMBL6145312)
Affinity DataIC50: 22nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654460BDBM50654460(CHEMBL6151561)
Affinity DataIC50: 23nMAssay Description:Inhibition of DYRK1A (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654466BDBM50654466(CHEMBL6151200)
Affinity DataIC50: 24nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654472BDBM50654472(CHEMBL6162982)
Affinity DataIC50: 26nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654474BDBM50654474(CHEMBL6145661)
Affinity DataIC50: 34nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654462BDBM50654462(CHEMBL6162590)
Affinity DataIC50: 35nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654464BDBM50654464(CHEMBL6149751)
Affinity DataIC50: 41nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654470BDBM50654470(CHEMBL6165228)
Affinity DataIC50: 48nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654469BDBM50654469(CHEMBL6160301)
Affinity DataIC50: 81nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654463BDBM50654463(CHEMBL6151584)
Affinity DataIC50: 186nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654458BDBM50654458(CHEMBL6091951)
Affinity DataIC50: 425nMAssay Description:Inhibition of DYRK1A (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed