Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50022744
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653804BDBM50653804(CHEMBL6145158)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572111BDBM50572111(CHEMBL4875422)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572108BDBM50572108(CHEMBL4869082 | US20240043448, Example 4a)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572115BDBM50572115(CHEMBL4864188 | US20240043448, Example 75)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650992BDBM650992(US20240043448, Example 52)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653803BDBM50653803(CHEMBL6101960)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 651006BDBM651006(2-[(2S,5R)-2,5-Dimethyl-4-(prop- 2-enoyl)piperazin...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572110BDBM50572110(CHEMBL4866126 | US20240043448, Example 10b)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653806BDBM50653806(CHEMBL6132774)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572108BDBM50572108(CHEMBL4869082 | US20240043448, Example 4a)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653803BDBM50653803(CHEMBL6101960)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 651003BDBM651003(2-[(2S,5R)-2,5-Dimethyl-4-(prop- 2-enoyl)piperazin...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572110BDBM50572110(CHEMBL4866126 | US20240043448, Example 10b)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650980BDBM650980(2-[(2S,5R)-2,5-dimethyl-4- (prop-2-enoyl)piperazin...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650992BDBM650992(US20240043448, Example 52)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653805BDBM50653805(CHEMBL6102892)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572115BDBM50572115(CHEMBL4864188 | US20240043448, Example 75)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653804BDBM50653804(CHEMBL6145158)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572111BDBM50572111(CHEMBL4875422)
Affinity DataIC50: 9nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 651003BDBM651003(2-[(2S,5R)-2,5-Dimethyl-4-(prop- 2-enoyl)piperazin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650980BDBM650980(2-[(2S,5R)-2,5-dimethyl-4- (prop-2-enoyl)piperazin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650786BDBM650786(US20240043448, Example 1a)
Affinity DataIC50: 11nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653805BDBM50653805(CHEMBL6102892)
Affinity DataIC50: 16nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650786BDBM650786(US20240043448, Example 1a)
Affinity DataIC50: 21nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 651006BDBM651006(2-[(2S,5R)-2,5-Dimethyl-4-(prop- 2-enoyl)piperazin...)
Affinity DataIC50: 28nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653806BDBM50653806(CHEMBL6132774)
Affinity DataIC50: 30nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650972BDBM650972(US20240043448, Example 9)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 650972BDBM650972(US20240043448, Example 9)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed