Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50023724
TargetHistone deacetylase 6(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human HDAC10 using Ac-spermidine-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HDAC3 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446481BDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC11 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446481BDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human HDAC11 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446481BDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005711BDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105327BDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human HDAC10 using Ac-spermidine-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446481BDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human HDAC9 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 10nMAssay Description:Inhibition of human HDAC3 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667369BDBM50667369(CHEMBL6193423)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed