Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50022743
TargetSpike glycoprotein(2019-nCoV)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341448BDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataKd:  2.60nMAssay Description:Agonist activity at rat recombinant muscarinic M5 receptor by HTS cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604966BDBM50604966(CHEMBL5175530)
Affinity DataKi:  5.10nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653798BDBM50653798(CHEMBL6142557)
Affinity DataKi:  11nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetRho-associated protein kinase 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087135BDBM50087135(CHEMBL3426621 | US12479866, Compound Ripasudil)
Affinity DataIC50: 20nMAssay Description:Agonist activity at human recombinant muscarinic M2 receptor by HTS cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653794BDBM50653794(CHEMBL6142430)
Affinity DataIC50: 30nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653793BDBM50653793(CHEMBL6133552)
Affinity DataIC50: 30nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77607BDBM77607(US20250387403, Example Table1.20)
Affinity DataKi:  46nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetRho-associated protein kinase 1(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087135BDBM50087135(CHEMBL3426621 | US12479866, Compound Ripasudil)
Affinity DataIC50: 51nMAssay Description:Agonist activity at human recombinant muscarinic M2 receptor by HTS cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79455BDBM79455(US20250387403, Example Table1.32)
Affinity DataKi:  61nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653799BDBM50653799(CHEMBL6143117)
Affinity DataKi:  116nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 11(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 540nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 11(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 850nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V2 receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653791BDBM50653791(CHEMBL6151557)
Affinity DataIC50: 1.20E+3nMAssay Description:Agonist activity at human recombinant muscarinic M4 receptor by HTS cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 11(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653794BDBM50653794(CHEMBL6142430)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V2 receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653792BDBM50653792(CHEMBL4303142)
Affinity DataIC50: 1.20E+3nMAssay Description:Agonist activity at human recombinant muscarinic M4 receptor by HTS cell based assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/3/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 11(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653793BDBM50653793(CHEMBL6133552)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 11(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79459BDBM79459(US20250387403, Example Table1.36)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653793BDBM50653793(CHEMBL6133552)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653802BDBM50653802(CHEMBL6133252)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653801BDBM50653801(CHEMBL6132882)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653794BDBM50653794(CHEMBL6142430)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of acid-induced matriptase activation in human 184A1N4 cells using mAb M69 by cell-based ELISA like assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 9(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 5(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPolyamine deacetylase HDAC10(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPolyamine deacetylase HDAC10(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604966BDBM50604966(CHEMBL5175530)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 5(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSphingosine kinase 1(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277232BDBM50277232(CHEMBL4170798)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 9(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653791BDBM50653791(CHEMBL6151557)
Affinity DataIC50: 1.40E+4nMAssay Description:Agonist activity at human recombinant muscarinic M3 receptor by HTS cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPolyamine deacetylase HDAC10(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653796BDBM50653796(CHEMBL6144214)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653792BDBM50653792(CHEMBL4303142)
Affinity DataIC50: 1.40E+4nMAssay Description:Agonist activity at human recombinant muscarinic M3 receptor by HTS cell based assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 7(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 3(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 5(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653795BDBM50653795(CHEMBL6092066)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 7(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 3(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252390BDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 9(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653793BDBM50653793(CHEMBL6133552)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
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