Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50023629
Affinity DataKi: <0.0500nMAssay Description:Binding affinity to His-tagged MER (571 to 864 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as inhibition con...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Binding affinity to His-tagged Axl intracellular domain (473 to 894 residues) (unknown origin) extracted from Sf21 cells assessed as inhibition const...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of MER (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MER (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dezhou University
Curated by ChEMBL
Dezhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 6xHis-tagged MCL-1 (171 to 327 residues) extracted from Escherichia coli using (Biotin-DMRPEIWIAQELRRIGDEFNAYYARR) as...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to Keap1-Nrf2 (unknown origin) assessed as dissociation constant measured for 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dezhou University
Curated by ChEMBL
Dezhou University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 6xHis-tagged MCL-1 (171 to 327 residues) extracted from Escherichia coli using (Biotin-DMRPEIWIAQELRRIGDEFNAYYARR) as...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as fluorogenic substrate incubated for 60 mins by MCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant Axl using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATP by radiometric HotSpot kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant FLT3 using Poly(Ala,Glu,Lys,Tyr)6:2:5:1 as substrate in presence of [gamma33P]-ATP by radiometric HotSpot kinase assa...More data for this Ligand-Target Pair
