Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50022426
TargetTopoisomerase IV(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366824BDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 12nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-IV assessed as reduction in decatenation using kinetoplast DNA as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652127BDBM50652127(CHEMBL5647058)
Affinity DataIC50: 16nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-IV assessed as reduction in decatenation using kinetoplast DNA as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652128BDBM50652128(CHEMBL5641537)
Affinity DataIC50: 31nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide staining based aga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366824BDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 40nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-IV assessed as reduction in decatenation using kinetoplast DNA as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652127BDBM50652127(CHEMBL5647058)
Affinity DataIC50: 52nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide staining based aga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTopoisomerase IV(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652128BDBM50652128(CHEMBL5641537)
Affinity DataIC50: 206nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-IV assessed as reduction in decatenation using kinetoplast DNA as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 391nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366824BDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50: 400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide staining based aga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652127BDBM50652127(CHEMBL5647058)
Affinity DataIC50: 400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide staining based aga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kazan (Volga region) Federal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652128BDBM50652128(CHEMBL5641537)
Affinity DataIC50: 760nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed