Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50020391
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629522BDBM50629522(CHEMBL5429670)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629523BDBM50629523(CHEMBL5427979)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629521BDBM50629521(CHEMBL5434479)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629524BDBM50629524(CHEMBL5398785)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629520BDBM50629520(CHEMBL5432959)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of PDE4 (unknown origin) using fluorescein-cAMP as substrate incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed