Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50018485
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608650BDBM50608650(CHEMBL5271348)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608648BDBM50608648(CHEMBL5286715)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608649BDBM50608649(CHEMBL5290499)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608647BDBM50608647(CHEMBL5267724)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518950BDBM50518950(CHEMBL4468881)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608646BDBM50608646(CHEMBL5288936)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608668BDBM50608668(CHEMBL5282942)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21691BDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608666BDBM50608666(CHEMBL5267457)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608645BDBM50608645(CHEMBL4535844)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608667BDBM50608667(CHEMBL5271201)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608643BDBM50608643(CHEMBL5274431)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608644BDBM50608644(CHEMBL4570053)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608657BDBM50608657(CHEMBL5278136)
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198240BDBM50198240(CHEMBL3908487)
Affinity DataIC50: 58nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198237BDBM50198237(CHEMBL3898662)
Affinity DataIC50: 58nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608663BDBM50608663(CHEMBL5272532)
Affinity DataIC50: 73nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608655BDBM50608655(CHEMBL5280982)
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608662BDBM50608662(CHEMBL5284259)
Affinity DataIC50: 140nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174319BDBM50174319(CHEMBL3809184)
Affinity DataIC50: 180nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608669BDBM50608669(CHEMBL3884935)
Affinity DataIC50: 510nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608653BDBM50608653(CHEMBL5281268)
Affinity DataIC50: 619nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608642BDBM50608642(CHEMBL5290948)
Affinity DataIC50: 750nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608671BDBM50608671(CHEMBL3883383)
Affinity DataIC50: 770nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608670BDBM50608670(CHEMBL3883797)
Affinity DataIC50: 820nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608654BDBM50608654(CHEMBL5267215)
Affinity DataIC50: 970nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608656BDBM50608656(CHEMBL5271712)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608658BDBM50608658(CHEMBL5272437)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 166663BDBM166663(N-(4-(4-Hydrazinyl-4-oxobutanamido)phenyl)-5-methy...)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseB ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608659BDBM50608659(CHEMBL5285496)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 166646BDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608651BDBM50608651(CHEMBL3906178)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249787BDBM50249787(CHEMBL4752218)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045000BDBM50045000(CHEMBL9 | (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-pi...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608661BDBM50608661(CHEMBL5286132)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608660BDBM50608660(CHEMBL5272158)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608652BDBM50608652(CHEMBL5281739)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608664BDBM50608664(CHEMBL5280084)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608665BDBM50608665(CHEMBL4637080)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Queensland University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21691BDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed