Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50019131
LigandChemical structure of BindingDB Monomer ID 50369240BDBM50369240(GANAXOLONE)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50615577BDBM50615577(CHEMBL5281882)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50369240BDBM50369240(GANAXOLONE)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615576BDBM50615576(CHEMBL5282680)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50615577BDBM50615577(CHEMBL5281882)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615572BDBM50615572(CHEMBL5283818)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615573BDBM50615573(CHEMBL5290461)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615574BDBM50615574(CHEMBL5272953)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615575BDBM50615575(CHEMBL5276729)
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed