Compile Data Set for Download or QSAR
Report error Found 427 Enz. Inhib. hit(s) with all data for entry = 11918
TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660990BDBM660990(Synthesis of N-((1R,3S)-3-((1-((2-chloropyrimidin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660992BDBM660992(Synthesis of N-((1 S,3R)-3-((1-((2-chloropyrimidin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660991BDBM660991(Synthesis of N-((1 S,3R)-3-((1-((2-chloropyrimidin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660985BDBM660985(N-(2-methoxypyrimidin-5-yl)- 6-((1-methyl-1H-pyraz...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660988BDBM660988(2-chloro-5-((6-((1-methyl-1H- pyrazol-4- yl)methox...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660987BDBM660987(1-(((1-((2-methoxypyrimidin-5- yl)amino)isoquinoli...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660732BDBM660732(N-(6-chloropyridin-3-yl)-6-((1- (oxetan-3-yl)-1H-p...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660998BDBM660998(N-(2-chloropyrimidin-5-yl)-6- ((1- fluorocycloprop...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660997BDBM660997((S)-6-((1,4-dioxan-2- yl)methoxy)-N-(2- chloropyri...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660703BDBM660703(1-(((1-((2-methylpyrimidin-5- yl)amino)isoquinolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660810BDBM660810(US20240101531, Example 196 | N-(6-chloropyridin-3-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660999BDBM660999(1-(1-((1-((2-chloropyrimidin-5- yl)amino)isoquinol...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660994BDBM660994(N-(6-chloropyridin-3-yl)-6-((1- (2,2-difluoroethyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660739BDBM660739(3-(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660993BDBM660993(N-(6-chloropyridin-3-yl)-6-((5- cyclopropyl-1H-pyr...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660738BDBM660738((R)-1-(3-((1-((6-chloropyridin- 3-yl)amino)isoquin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660996BDBM660996((R)-6-((1,4-dioxan-2- yl)methoxy)-N-(2- chloropyri...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660741BDBM660741(Synthesis of (R)-3-(((1-((6-chloropyridin-3-yl)ami...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660995BDBM660995(6-((1H-pyrazol-4-yl)methoxy)- N-(2-chloropyimidin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660740BDBM660740(Synthesis of (R)-3-(((1-((6-chloropyridin-3-yl)ami...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660974BDBM660974(cis-N-(2-chloropyrimidin-5-yl)- 6-(((1S,3R)-3- met...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660973BDBM660973(Synthesis of (1R,3S)-3-((1-((2-chloropyrimidin-5-y...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660718BDBM660718(rac-(1R,3R)-3-((1-((6- chloropyridin-3- yl)amino)i...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660975BDBM660975(1-(((1-((2-chloropyrimidin-5- yl)amino)isoquinolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660970BDBM660970(tert-butyl ((1S,3R)-3-((1-((2- chloropyrimidin-5- ...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660715BDBM660715(Cis-4-((1-((6-chloropyridin-3- yl)amino)isoquinoli...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660969BDBM660969(N-(2-chloropyrimidin-5-yl)-6- ((3-(1,1-difluoroeth...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660962BDBM660962(US20240101531, Example 348 | US20240101531, Exampl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660717BDBM660717(rac-(1S,3R)-3-((1-((6- chloropyridin-3- yl)amino)i...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660953BDBM660953(US20240101531, Example 339 | US20240101531, Exampl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660982BDBM660982(N-(6-chloropyridin-3-yl)-6- (isoxazol-4- ylmethoxy...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660981BDBM660981(trans-3-(((1-((2- chloropyrimidin-5- yl)amino)isoq...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660984BDBM660984(N-(2-methoxypyrimidin-5-yl)- 6-((3-methyloxetan-3-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660729BDBM660729(6-((1-oxaspiro[3.3]heptan-6- yl)methoxy)-N-(6- chl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660983BDBM660983(1-(((1-((2-chloropyrimidin-5- yl)amino)isoquinolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660728BDBM660728(6-((2-oxaspiro[3.3]heptan-6- yl)oxy)-N-(6-chloropy...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660978BDBM660978(Synthesis of (R) N-(6-chloropyridin-3-yl)-6-((3-fl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660977BDBM660977(N-(6-chloropyridin-3-yl)-6-((3- fluorotetrahydrofu...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660979BDBM660979(Synthesis of (R) N-(6-chloropyridin-3-yl)-6-((3-fl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660767BDBM660767(N-(6-chloropyridin-3-yl)-6-((3- isopropyloxetan-3-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660766BDBM660766(N-(6-chloropyridin-3-yl)-6-((1- ethynylcyclopropyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660769BDBM660769(6-((1,4-dioxan-2-yl)methoxy)- N-(6-chloropyridin-3...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660768BDBM660768(6-((1-((6-chloropyridin-3- yl)amino)isoquinolin-6-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 661018BDBM661018(N-(6-chloropyridin-3-yl)-6- ((2,2- difluorocyclopr...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660763BDBM660763(Synthesis of (1S,3R)-3-((1-((6-chloropyridin-3-yl)...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660762BDBM660762(2-(1-(((1-((2-chloropyrimidin- 5-yl)amino)isoquino...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 661020BDBM661020(N-(6-chloropyridin-3-yl)-6-((2- methyltetrahydrofu...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660765BDBM660765(N-(6-chloropyridin-3-yl)-6-((1- methyl-1H-pyrazol-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660764BDBM660764(Synthesis of (1S,3R)-3-((1-((6-chloropyridin-3-yl)...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 661029BDBM661029(N-(6-chloropyridin-3-yl)-6- ((tetrahydrofuran-3- y...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

Displayed 1 to 50 (of 427 total ) | Next | Last >>
Jump to: