BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
51160549	COc1cc(cc(Br)c1OC)C1C(C#N)=C(N)Oc2c(N)c(N)ccc12	InChI=1S/C18H17BrN4O3/c1-24-13-6-8(5-11(19)17(13)25-2)14-9-3-4-12(21)15(22)16(9)26-18(23)10(14)7-20/h3-6,14H,21-23H2,1-2H3	JXONINOYTKKXQQ-UHFFFAOYSA-N	50475438	CHEMBL364477	Tubulin beta-4B chain			<500000							ChEMBL	10.1016/j.bmcl.2005.07.066	10.7270/Q27M0BP3	16143530			Kemnitzer, W; Kasibhatla, S; Jiang, S; Zhang, H; Zhao, J; Jia, S; Xu, L; Crogan-Grundy, C; Denis, R; Barriault, N; Vaillancourt, L; Charron, S; Dodd, J; Attardo, G; Labrecque, D; Lamothe, S; Gourdeau, H; Tseng, B; Drewe, J; Cai, SX	Maxim Pharmaceuticals, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50475438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007918&target=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50475438&enzyme=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	BG0	6JCJ	10202048	433942703							1	MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA	1IA0,1SA0,1SA1,2HXF,2HXH,2P4N,2WBE,3DCO,3EDL,3IZ0,3J2U,3J6P,3J7I,3JAK,3JAL,3JAO,3JAR,3JAS,3JAT,3JAW,4ABO,4UXO,4UXP,4UXR,4UXS,4UXT,4UXY,4ZHQ,4ZI7,4ZOL,5BMV,5FNV,5JQG,5KMG,5OAM,5OCU,5OGC,5Z4U,6BJC,6CVJ,6CVN,6DPU,6DPV,6DPW,6EVX,6EVY,6EVZ,6EW0,6MLQ,6MLR,6MZE,6MZF,6MZG,6O2Q,6O2R,6VPO,6VPP,6Y4M,6Y4N,6ZPI,7DMZ,7DN0,7EMJ,7EXC,7L05,7NB8,7NBA,7PQC,7PQP,7RS5,7RS6,7RX0,7SGS,7U0F,7X4N,8OU0	Tubulin beta-4B chain	TBB4B_HUMAN	P68371	A2BFA2 P05217						
51160550	COc1cc(cc(Br)c1OC)C1C(C#N)=C(N)Oc2cc(N)ccc12	InChI=1S/C18H16BrN3O3/c1-23-15-6-9(5-13(19)17(15)24-2)16-11-4-3-10(21)7-14(11)25-18(22)12(16)8-20/h3-7,16H,21-22H2,1-2H3	NAGAMFAAQBJQOY-UHFFFAOYSA-N	50475439	CHEMBL383775	Tubulin beta-4B chain			<500							ChEMBL	10.1016/j.bmcl.2005.07.066	10.7270/Q27M0BP3	16143530			Kemnitzer, W; Kasibhatla, S; Jiang, S; Zhang, H; Zhao, J; Jia, S; Xu, L; Crogan-Grundy, C; Denis, R; Barriault, N; Vaillancourt, L; Charron, S; Dodd, J; Attardo, G; Labrecque, D; Lamothe, S; Gourdeau, H; Tseng, B; Drewe, J; Cai, SX	Maxim Pharmaceuticals, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50475439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007918&target=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50475439&enzyme=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search			10294498	433942704							1	MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA	1IA0,1SA0,1SA1,2HXF,2HXH,2P4N,2WBE,3DCO,3EDL,3IZ0,3J2U,3J6P,3J7I,3JAK,3JAL,3JAO,3JAR,3JAS,3JAT,3JAW,4ABO,4UXO,4UXP,4UXR,4UXS,4UXT,4UXY,4ZHQ,4ZI7,4ZOL,5BMV,5FNV,5JQG,5KMG,5OAM,5OCU,5OGC,5Z4U,6BJC,6CVJ,6CVN,6DPU,6DPV,6DPW,6EVX,6EVY,6EVZ,6EW0,6MLQ,6MLR,6MZE,6MZF,6MZG,6O2Q,6O2R,6VPO,6VPP,6Y4M,6Y4N,6ZPI,7DMZ,7DN0,7EMJ,7EXC,7L05,7NB8,7NBA,7PQC,7PQP,7RS5,7RS6,7RX0,7SGS,7U0F,7X4N,8OU0	Tubulin beta-4B chain	TBB4B_HUMAN	P68371	A2BFA2 P05217						
51034026	CCc1nnc2c(Nc3ccc(cc3)C(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)nc3ccccc3n12	InChI=1S/C29H27N5O4/c1-5-26-32-33-29-28(31-21-8-6-7-9-22(21)34(26)29)30-20-13-11-19(12-14-20)23(35)15-10-18-16-24(36-2)27(38-4)25(17-18)37-3/h6-17H,5H2,1-4H3,(H,30,31)/b15-10+	IFPNFAIDTHYHMR-XNTDXEJSSA-N	50594719	CHEMBL5186583	Tubulin beta-4B chain			 8400							ChEMBL		10.7270/Q2TF02JJ	34450497			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007918&target=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594719&enzyme=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search			168278620	482605571							1	MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA	1IA0,1SA0,1SA1,2HXF,2HXH,2P4N,2WBE,3DCO,3EDL,3IZ0,3J2U,3J6P,3J7I,3JAK,3JAL,3JAO,3JAR,3JAS,3JAT,3JAW,4ABO,4UXO,4UXP,4UXR,4UXS,4UXT,4UXY,4ZHQ,4ZI7,4ZOL,5BMV,5FNV,5JQG,5KMG,5OAM,5OCU,5OGC,5Z4U,6BJC,6CVJ,6CVN,6DPU,6DPV,6DPW,6EVX,6EVY,6EVZ,6EW0,6MLQ,6MLR,6MZE,6MZF,6MZG,6O2Q,6O2R,6VPO,6VPP,6Y4M,6Y4N,6ZPI,7DMZ,7DN0,7EMJ,7EXC,7L05,7NB8,7NBA,7PQC,7PQP,7RS5,7RS6,7RX0,7SGS,7U0F,7X4N,7YSN,7YSO,7YSP,8OU0,8TO0	Tubulin beta-4B chain	TBB4B_HUMAN	P68371	A2BFA2 P05217						
51034028	C\C(CN1CCN([C@H](Cc2c[nH]c3ccccc23)C1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)=N\OCCN	InChI=1S/C27H29F6N5O2/c1-17(36-40-9-6-34)15-37-7-8-38(22(16-37)12-19-14-35-24-5-3-2-4-23(19)24)25(39)18-10-20(26(28,29)30)13-21(11-18)27(31,32)33/h2-5,10-11,13-14,22,35H,6-9,12,15-16,34H2,1H3/b36-17-/t22-/m1/s1	RXHOOMSRVGJWKW-MRWAXMPCSA-N	50410801	CHEMBL5276251	Tubulin beta-4B chain			 5510							ChEMBL		10.7270/Q2TF02JJ	34450497			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007918&target=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410801&enzyme=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search			44408039	163359825		CHEMBL204297				ZINC28570626	1	MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA	1IA0,1SA0,1SA1,2HXF,2HXH,2P4N,2WBE,3DCO,3EDL,3IZ0,3J2U,3J6P,3J7I,3JAK,3JAL,3JAO,3JAR,3JAS,3JAT,3JAW,4ABO,4UXO,4UXP,4UXR,4UXS,4UXT,4UXY,4ZHQ,4ZI7,4ZOL,5BMV,5FNV,5JQG,5KMG,5OAM,5OCU,5OGC,5Z4U,6BJC,6CVJ,6CVN,6DPU,6DPV,6DPW,6EVX,6EVY,6EVZ,6EW0,6MLQ,6MLR,6MZE,6MZF,6MZG,6O2Q,6O2R,6VPO,6VPP,6Y4M,6Y4N,6ZPI,7DMZ,7DN0,7EMJ,7EXC,7L05,7NB8,7NBA,7PQC,7PQP,7RS5,7RS6,7RX0,7SGS,7U0F,7X4N,7YSN,7YSO,7YSP,8OU0,8TO0	Tubulin beta-4B chain	TBB4B_HUMAN	P68371	A2BFA2 P05217						
51034034	CNCCO\N=C(\C)CN1CCN([C@H](Cc2c[nH]c3ccccc23)C1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F	InChI=1S/C28H31F6N5O2/c1-18(37-41-10-7-35-2)16-38-8-9-39(23(17-38)13-20-15-36-25-6-4-3-5-24(20)25)26(40)19-11-21(27(29,30)31)14-22(12-19)28(32,33)34/h3-6,11-12,14-15,23,35-36H,7-10,13,16-17H2,1-2H3/b37-18-/t23-/m1/s1	BLRGEKISNDSGSY-XIDPYBFFSA-N	50410800	CHEMBL5206193	Tubulin beta-4B chain			 108							ChEMBL		10.7270/Q2TF02JJ	34450497			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007918&target=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410800&enzyme=Tubulin+beta-4B+chain&column=ki&startPg=0&Increment=50&submit=Search			44408045	163359824		CHEMBL204691					1	MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA	1IA0,1SA0,1SA1,2HXF,2HXH,2P4N,2WBE,3DCO,3EDL,3IZ0,3J2U,3J6P,3J7I,3JAK,3JAL,3JAO,3JAR,3JAS,3JAT,3JAW,4ABO,4UXO,4UXP,4UXR,4UXS,4UXT,4UXY,4ZHQ,4ZI7,4ZOL,5BMV,5FNV,5JQG,5KMG,5OAM,5OCU,5OGC,5Z4U,6BJC,6CVJ,6CVN,6DPU,6DPV,6DPW,6EVX,6EVY,6EVZ,6EW0,6MLQ,6MLR,6MZE,6MZF,6MZG,6O2Q,6O2R,6VPO,6VPP,6Y4M,6Y4N,6ZPI,7DMZ,7DN0,7EMJ,7EXC,7L05,7NB8,7NBA,7PQC,7PQP,7RS5,7RS6,7RX0,7SGS,7U0F,7X4N,7YSN,7YSO,7YSP,8OU0,8TO0	Tubulin beta-4B chain	TBB4B_HUMAN	P68371	A2BFA2 P05217