BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51131079 CNc1cc(F)cc2c1[nH]c1nc(CNC(=O)c3cocn3)nc(N3CCC(N)C3)c21 InChI=1S/C20H21FN8O2/c1-23-13-5-10(21)4-12-16-18(28-17(12)13)26-15(6-24-20(30)14-8-31-9-25-14)27-19(16)29-3-2-11(22)7-29/h4-5,8-9,11,23H,2-3,6-7,22H2,1H3,(H,24,30)(H,26,27,28) WRRYWYLIRTYXGI-UHFFFAOYSA-N 50463770 CHEMBL4238919 DNA gyrase subunit B 5.0 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463770&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 121304725 433931035 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51131080 CNc1cc(F)cc2c1[nH]c1nc(CNC(=O)c3cocn3)nc(N3CCC(N)C3)c21 InChI=1S/C20H21FN8O2/c1-23-13-5-10(21)4-12-16-18(28-17(12)13)26-15(6-24-20(30)14-8-31-9-25-14)27-19(16)29-3-2-11(22)7-29/h4-5,8-9,11,23H,2-3,6-7,22H2,1H3,(H,24,30)(H,26,27,28) WRRYWYLIRTYXGI-UHFFFAOYSA-N 50463770 CHEMBL4238919 DNA gyrase subunit B 25 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463770&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 121304725 433931035 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51131081 CNc1cc(F)cc2c1[nH]c1nc(CNC(=O)c3cnco3)nc(N3CCC(N)C3)c21 InChI=1S/C20H21FN8O2/c1-23-13-5-10(21)4-12-16-18(28-17(12)13)26-15(7-25-20(30)14-6-24-9-31-14)27-19(16)29-3-2-11(22)8-29/h4-6,9,11,23H,2-3,7-8,22H2,1H3,(H,25,30)(H,26,27,28) BANJIAOWENUTAO-UHFFFAOYSA-N 50463771 CHEMBL4250651 DNA gyrase subunit B 59 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463771&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 121304735 433931036 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51131082 CNc1cc(F)cc2c1[nH]c1nc(CNC(=O)c3cnco3)nc(N3CCC(N)C3)c21 InChI=1S/C20H21FN8O2/c1-23-13-5-10(21)4-12-16-18(28-17(12)13)26-15(7-25-20(30)14-6-24-9-31-14)27-19(16)29-3-2-11(22)8-29/h4-6,9,11,23H,2-3,7-8,22H2,1H3,(H,25,30)(H,26,27,28) BANJIAOWENUTAO-UHFFFAOYSA-N 50463771 CHEMBL4250651 DNA gyrase subunit B 10.0 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463771&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 121304735 433931036 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51131083 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-N 50226181 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::CHEMBL36506::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(4-methyl-pent-3-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester(Novobiocin)::NOVOBIOCIN DNA gyrase subunit B 85 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226181&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NOV 1AJ6,4URO,4URN,1S14,7PTF,1KIJ,6B89,3LPS,6Y8O,6Y8L,7PQI,6TBE,6MIT 54675769 104097057 28368 CHEMBL36506 DB01051 C05080 ZINC14879999 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51131084 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-N 50226181 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::CHEMBL36506::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(4-methyl-pent-3-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester(Novobiocin)::NOVOBIOCIN DNA gyrase subunit B 20 ChEMBL 10.1016/j.bmcl.2018.05.049 10.7270/Q2G73HD3 30122228 McGarry, DH; Cooper, IR; Walker, R; Warrilow, CE; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Moyo, E; Maclean, J; Smith, A; Charrier, C; Stokes, NR; Lindsay, DM; Kerr, WJ Redx Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226181&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NOV 1AJ6,4URO,4URN,1S14,7PTF,1KIJ,6B89,3LPS,6Y8O,6Y8L,7PQI,6TBE,6MIT 54675769 104097057 28368 CHEMBL36506 DB01051 C05080 ZINC14879999 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51130464 C(c1ccc2OCOc2c1)n1c(nc2ccccc12)-c1ccc2OCOc2c1 InChI=1S/C22H16N2O4/c1-2-4-17-16(3-1)23-22(15-6-8-19-21(10-15)28-13-26-19)24(17)11-14-5-7-18-20(9-14)27-12-25-18/h1-10H,11-13H2 ZALVNSXRQJNDKF-UHFFFAOYSA-N 50463548 CHEMBL4239753 DNA gyrase subunit B 85736 ChEMBL 10.1016/j.bmc.2018.07.049 10.7270/Q2XD14C3 30097361 Chaturvedi, AK; Verma, AK; Thakur, JP; Roy, S; Bhushan Tripathi, S; Kumar, BS; Khwaja, S; Sachan, NK; Sharma, A; Chanda, D; Shanker, K; Saikia, D; Negi, AS CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463548&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 1103562 433930813 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51130465 COc1ccc2n(Cc3ccc4OCOc4c3)c(nc2c1)-c1ccc2OCOc2c1 InChI=1S/C23H18N2O5/c1-26-16-4-5-18-17(10-16)24-23(15-3-7-20-22(9-15)30-13-28-20)25(18)11-14-2-6-19-21(8-14)29-12-27-19/h2-10H,11-13H2,1H3 WKZRCXZKIMKIMG-UHFFFAOYSA-N 50463549 CHEMBL4237298 DNA gyrase subunit B 294097 ChEMBL 10.1016/j.bmc.2018.07.049 10.7270/Q2XD14C3 30097361 Chaturvedi, AK; Verma, AK; Thakur, JP; Roy, S; Bhushan Tripathi, S; Kumar, BS; Khwaja, S; Sachan, NK; Sharma, A; Chanda, D; Shanker, K; Saikia, D; Negi, AS CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463549&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 145983706 433930814 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51130466 COc1ccc2n(Cc3ccccc3OC)c(nc2c1)-c1ccccc1OC InChI=1S/C23H22N2O3/c1-26-17-12-13-20-19(14-17)24-23(18-9-5-7-11-22(18)28-3)25(20)15-16-8-4-6-10-21(16)27-2/h4-14H,15H2,1-3H3 CWBQTHNAMYBKMN-UHFFFAOYSA-N 50463550 CHEMBL4251156 DNA gyrase subunit B 358288 ChEMBL 10.1016/j.bmc.2018.07.049 10.7270/Q2XD14C3 30097361 Chaturvedi, AK; Verma, AK; Thakur, JP; Roy, S; Bhushan Tripathi, S; Kumar, BS; Khwaja, S; Sachan, NK; Sharma, A; Chanda, D; Shanker, K; Saikia, D; Negi, AS CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463550&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 145986056 433930815 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51130467 COc1ccc2[nH]c(nc2c1)-c1ccc(F)cc1 InChI=1S/C14H11FN2O/c1-18-11-6-7-12-13(8-11)17-14(16-12)9-2-4-10(15)5-3-9/h2-8H,1H3,(H,16,17) BXXMOPZRTKSYGA-UHFFFAOYSA-N 50463551 CHEMBL4243541 DNA gyrase subunit B 379649 ChEMBL 10.1016/j.bmc.2018.07.049 10.7270/Q2XD14C3 30097361 Chaturvedi, AK; Verma, AK; Thakur, JP; Roy, S; Bhushan Tripathi, S; Kumar, BS; Khwaja, S; Sachan, NK; Sharma, A; Chanda, D; Shanker, K; Saikia, D; Negi, AS CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463551&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 65017411 433930816 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51175417 COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin DNA gyrase subunit B 6000 ChEMBL 10.1128/AAC.01380-07 10.7270/Q2862K8J 18426901 Matrat, S; Aubry, A; Mayer, C; Jarlier, V; Cambau, E Universit£ Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366824&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search MFX 4Z3O,4Z2C,5CDQ,2XKK,5BS8,3FOF,5BTA 152946 160845926 63611 DB00218 C07663 ZINC03826253 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51175418 CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1 InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23) IDYZIJYBMGIQMJ-UHFFFAOYSA-N 50296358 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid::1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid::AT-2266::CHEMBL826::CI-919::ENOXACIN::PD-107779::Penetrex::enofloxacin DNA gyrase subunit B 156000 ChEMBL 10.1128/AAC.01380-07 10.7270/Q2862K8J 18426901 Matrat, S; Aubry, A; Mayer, C; Jarlier, V; Cambau, E Universit£ Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296358&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 3229 104137889 157175 CHEMBL826 DB00467 C06979 ZINC19594549 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51175421 CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12 InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17) MHWLWQUZZRMNGJ-UHFFFAOYSA-N 21691 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid::Nalidixic Acid::Nalidixin::NegGram::Nevigramon::US9138393, Nalidixic acid::US9144538, Nalidixic acid DNA gyrase subunit B 4750000 ChEMBL 10.1128/AAC.01380-07 10.7270/Q2862K8J 18426901 Matrat, S; Aubry, A; Mayer, C; Jarlier, V; Cambau, E Universit£ Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21691&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NIX 2BQ2 4421 49700798 100147 DB00779 C05079 ZINC00057421 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51175422 CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25) GSDSWSVVBLHKDQ-UHFFFAOYSA-N 50045004 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid::CHEMBL4::OFLOXACIN::OFLX DNA gyrase subunit B 28000 ChEMBL 10.1128/AAC.01380-07 10.7270/Q2862K8J 18426901 Matrat, S; Aubry, A; Mayer, C; Jarlier, V; Cambau, E Universit£ Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045004&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search LFX 7B8T,4Z2D,3RAE,5EIX,3K9F,4JUO,5BTI,5BTG 4583 103976108 7731 CHEMBL4 DB01165 C07321 ZINC00538273 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191889 CCOC(=O)C1CN(CCN1)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O6/c1-3-31-21(29)15-10-24(7-6-23-15)17-14(22)8-12-16(19(17)30-2)25(11-4-5-11)9-13(18(12)26)20(27)28/h8-9,11,15,23H,3-7,10H2,1-2H3,(H,27,28) WNYDEDYUJPUQCP-UHFFFAOYSA-N 50490565 CHEMBL2338465 DNA gyrase subunit B 48400 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490565&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524959 433957830 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191890 OC(=O)C1CN(CCN1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1 InChI=1S/C18H18FN3O5/c19-12-5-10-14(6-15(12)21-4-3-20-13(8-21)18(26)27)22(9-1-2-9)7-11(16(10)23)17(24)25/h5-7,9,13,20H,1-4,8H2,(H,24,25)(H,26,27) QJZVWIRZVZHXHX-UHFFFAOYSA-N 50490566 CHEMBL2338466 DNA gyrase subunit B 53200 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490566&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524998 433957831 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191891 COc1c(N2CCNC(C2)C(O)=O)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C19H20FN3O6/c1-29-17-14-10(16(24)11(18(25)26)7-23(14)9-2-3-9)6-12(20)15(17)22-5-4-21-13(8-22)19(27)28/h6-7,9,13,21H,2-5,8H2,1H3,(H,25,26)(H,27,28) DHQKMDASURGTBV-UHFFFAOYSA-N 50490567 CHEMBL2338467 DNA gyrase subunit B 39400 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490567&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 69492574 433957832 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191892 OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24) MYSWGUAQZAJSOK-UHFFFAOYSA-N 21690 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid::1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid::Bay 09867::CHEMBL8::Ciprinol::Cipro::Ciprofloxacin::US11590142, Compound Ciprofloxacin::US9138393, Ciprofloxacin HCl::US9144538, Ciprofloxacin HCl DNA gyrase subunit B 18100 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21690&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search CPF 1OYE,2XCT,4KRA,4BVV,1T9U,5BTC 2764 49700797 100241 CHEMBL8 DB00537 C05349 ZINC00020220 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191893 CCN1CCN(CC1C(O)=O)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1 InChI=1S/C20H22FN3O5/c1-2-22-5-6-23(10-17(22)20(28)29)16-8-15-12(7-14(16)21)18(25)13(19(26)27)9-24(15)11-3-4-11/h7-9,11,17H,2-6,10H2,1H3,(H,26,27)(H,28,29) VSBIKKDSZFFFHF-UHFFFAOYSA-N 50490568 CHEMBL2338468 DNA gyrase subunit B 118000 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490568&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71525001 433957833 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191894 CCOC(=O)C1CN(CCN1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1 InChI=1S/C20H22FN3O5/c1-2-29-20(28)15-10-23(6-5-22-15)17-8-16-12(7-14(17)21)18(25)13(19(26)27)9-24(16)11-3-4-11/h7-9,11,15,22H,2-6,10H2,1H3,(H,26,27) NDNZKIATZHMBSF-UHFFFAOYSA-N 50490569 CHEMBL2338464 DNA gyrase subunit B 66900 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490569&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524958 433957834 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191895 CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25) GSDSWSVVBLHKDQ-UHFFFAOYSA-N 50045004 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid::CHEMBL4::OFLOXACIN::OFLX DNA gyrase subunit B 16600 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045004&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search LFX 7B8T,4Z2D,3RAE,5EIX,3K9F,4JUO,5BTI,5BTG 4583 103976108 7731 CHEMBL4 DB01165 C07321 ZINC00538273 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191896 COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) XUBOMFCQGDBHNK-UHFFFAOYSA-N 50117914 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid::1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::AM 1155::CHEMBL31::GATIFLOXACIN DNA gyrase subunit B 7990 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117914&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search GFN 7F35,5BTD,5BTF 5379 104011321 5280 CHEMBL31 DB01044 C07661 ZINC38197764 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191897 CCN1CCN(CC1C(O)=O)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O6/c1-3-23-6-7-24(10-15(23)21(29)30)17-14(22)8-12-16(19(17)31-2)25(11-4-5-11)9-13(18(12)26)20(27)28/h8-9,11,15H,3-7,10H2,1-2H3,(H,27,28)(H,29,30) YXAOKAQEEYOMRQ-UHFFFAOYSA-N 50490570 CHEMBL2338469 DNA gyrase subunit B 200000 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490570&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71525003 433957835 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191898 CCN(CC)C(=O)OCC1CN(CCN1)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C24H31FN4O6/c1-4-27(5-2)24(33)35-13-14-11-28(9-8-26-14)20-18(25)10-16-19(22(20)34-3)29(15-6-7-15)12-17(21(16)30)23(31)32/h10,12,14-15,26H,4-9,11,13H2,1-3H3,(H,31,32) VKAXQCIAHLYMCY-UHFFFAOYSA-N 50490571 CHEMBL2338471 DNA gyrase subunit B 101000 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490571&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524955 433957836 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191899 CCN(CC)C(=O)OCC1CN(CCN1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1 InChI=1S/C23H29FN4O5/c1-3-26(4-2)23(32)33-13-14-11-27(8-7-25-14)20-10-19-16(9-18(20)24)21(29)17(22(30)31)12-28(19)15-5-6-15/h9-10,12,14-15,25H,3-8,11,13H2,1-2H3,(H,30,31) NCXYCPHKIPJSIH-UHFFFAOYSA-N 50490572 CHEMBL2338470 DNA gyrase subunit B 575000 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490572&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524954 433957837 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191900 CCCCNC(=O)OCC1CN(CCN1)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C24H31FN4O6/c1-3-4-7-27-24(33)35-13-14-11-28(9-8-26-14)20-18(25)10-16-19(22(20)34-2)29(15-5-6-15)12-17(21(16)30)23(31)32/h10,12,14-15,26H,3-9,11,13H2,1-2H3,(H,27,33)(H,31,32) WMAIMBLUQSIZBY-UHFFFAOYSA-N 50490573 CHEMBL2338463 DNA gyrase subunit B 34600 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490573&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524957 433957838 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191901 COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin DNA gyrase subunit B 4980 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366824&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search MFX 4Z3O,4Z2C,5CDQ,2XKK,5BS8,3FOF,5BTA 152946 160845926 63611 DB00218 C07663 ZINC03826253 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51191902 CCCCNC(=O)OCC1CN(CCN1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1 InChI=1S/C23H29FN4O5/c1-2-3-6-26-23(32)33-13-14-11-27(8-7-25-14)20-10-19-16(9-18(20)24)21(29)17(22(30)31)12-28(19)15-4-5-15/h9-10,12,14-15,25H,2-8,11,13H2,1H3,(H,26,32)(H,30,31) XBIATPMTUUXULB-UHFFFAOYSA-N 50490574 CHEMBL2338462 DNA gyrase subunit B 65100 ChEMBL 10.1016/j.bmc.2012.12.011 10.7270/Q2FF3W92 23294829 Gomez, C; Ponien, P; Serradji, N; Lamouri, A; Pantel, A; Capton, E; Jarlier, V; Anquetin, G; Aubry, A Universit£ Paris Diderot http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50490574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50490574&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 71524956 433957839 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216822 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccccc3)c2c1 InChI=1S/C22H25N5O3/c1-30-18-15-20-19(23-16-18)7-8-21(28)27(20)14-11-25-9-12-26(13-10-25)22(29)24-17-5-3-2-4-6-17/h2-8,15-16H,9-14H2,1H3,(H,24,29) HDNBBLMDTZXPRB-UHFFFAOYSA-N 50500032 CHEMBL3741038 DNA gyrase subunit B 13520 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500032&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042672 433911933 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216823 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(cc3)[N+]([O-])=O)c2c1 InChI=1S/C22H24N6O4S/c1-32-18-14-20-19(23-15-18)6-7-21(29)27(20)13-10-25-8-11-26(12-9-25)22(33)24-16-2-4-17(5-3-16)28(30)31/h2-7,14-15H,8-13H2,1H3,(H,24,33) HNUXVKHUTXIYHU-UHFFFAOYSA-N 50500033 CHEMBL3741129 DNA gyrase subunit B 18520 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500033&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042004 433911934 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216824 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(F)cc3)c2c1 InChI=1S/C22H24FN5O3/c1-31-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(30)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,30) JFTNTGKIAZZIHV-UHFFFAOYSA-N 50500034 CHEMBL3739706 DNA gyrase subunit B 11610 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500034&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039378 433911935 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216825 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(C)cc3)c2c1 InChI=1S/C23H27N5O2S/c1-17-3-5-18(6-4-17)25-23(31)27-12-9-26(10-13-27)11-14-28-21-15-19(30-2)16-24-20(21)7-8-22(28)29/h3-8,15-16H,9-14H2,1-2H3,(H,25,31) CCNFMIUACRHGJN-UHFFFAOYSA-N 50500035 CHEMBL3739514 DNA gyrase subunit B 11460 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500035&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042342 433911936 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216826 COc1ccc(CNC(=O)N2CCN(CCn3c4cc(OC)cnc4ccc3=O)CC2)cc1 InChI=1S/C24H29N5O4/c1-32-19-5-3-18(4-6-19)16-26-24(31)28-12-9-27(10-13-28)11-14-29-22-15-20(33-2)17-25-21(22)7-8-23(29)30/h3-8,15,17H,9-14,16H2,1-2H3,(H,26,31) WGGNCESKTDNZOZ-UHFFFAOYSA-N 50500036 CHEMBL3739698 DNA gyrase subunit B 14580 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500036&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042343 433911937 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216827 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-N 50226181 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::CHEMBL36506::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(4-methyl-pent-3-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester(Novobiocin)::NOVOBIOCIN DNA gyrase subunit B 46000 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226181&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NOV 1AJ6,4URO,4URN,1S14,7PTF,1KIJ,6B89,3LPS,6Y8O,6Y8L,7PQI,6TBE,6MIT 54675769 104097057 28368 CHEMBL36506 DB01051 C05080 ZINC14879999 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216828 COc1ccc(CN2CCN(CCn3c4cc(OC)cnc4ccc3=O)CC2)cc1 InChI=1S/C23H28N4O3/c1-29-19-5-3-18(4-6-19)17-26-11-9-25(10-12-26)13-14-27-22-15-20(30-2)16-24-21(22)7-8-23(27)28/h3-8,15-16H,9-14,17H2,1-2H3 TZFYNMOZAYRWPT-UHFFFAOYSA-N 50500037 CHEMBL3741477 DNA gyrase subunit B 1340 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500037&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042369 433911938 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216829 COc1cnc2ccc(=O)n(CCN3CCN(Cc4ccc(Cl)cc4)CC3)c2c1 InChI=1S/C22H25ClN4O2/c1-29-19-14-21-20(24-15-19)6-7-22(28)27(21)13-12-25-8-10-26(11-9-25)16-17-2-4-18(23)5-3-17/h2-7,14-15H,8-13,16H2,1H3 OFSRQRYFJISGCX-UHFFFAOYSA-N 50500038 CHEMBL3740159 DNA gyrase subunit B 810 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500038&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039740 433911939 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216830 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)NCc3ccc(Cl)cc3)c2c1 InChI=1S/C23H26ClN5O2S/c1-31-19-14-21-20(25-16-19)6-7-22(30)29(21)13-10-27-8-11-28(12-9-27)23(32)26-15-17-2-4-18(24)5-3-17/h2-7,14,16H,8-13,15H2,1H3,(H,26,32) YJUJNFJYJAUTSZ-UHFFFAOYSA-N 50500039 CHEMBL3740857 DNA gyrase subunit B 950 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500039&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039738 433911940 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216831 COc1ccc(CNC(=S)N2CCN(CCn3c4cc(OC)cnc4ccc3=O)CC2)cc1 InChI=1S/C24H29N5O3S/c1-31-19-5-3-18(4-6-19)16-26-24(33)28-12-9-27(10-13-28)11-14-29-22-15-20(32-2)17-25-21(22)7-8-23(29)30/h3-8,15,17H,9-14,16H2,1-2H3,(H,26,33) PJTOYJRFXFMTIK-UHFFFAOYSA-N 50500040 CHEMBL3739437 DNA gyrase subunit B 15530 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500040&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039737 433911941 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216832 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)NCc3ccc(Cl)cc3)c2c1 InChI=1S/C23H26ClN5O3/c1-32-19-14-21-20(25-16-19)6-7-22(30)29(21)13-10-27-8-11-28(12-9-27)23(31)26-15-17-2-4-18(24)5-3-17/h2-7,14,16H,8-13,15H2,1H3,(H,26,31) MDUWYIKXDZUWCI-UHFFFAOYSA-N 50500041 CHEMBL3740954 DNA gyrase subunit B 920 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500041&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042344 433911942 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216833 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(cc3)C(C)=O)c2c1 InChI=1S/C24H27N5O3S/c1-17(30)18-3-5-19(6-4-18)26-24(33)28-12-9-27(10-13-28)11-14-29-22-15-20(32-2)16-25-21(22)7-8-23(29)31/h3-8,15-16H,9-14H2,1-2H3,(H,26,33) OKTLPFNYSPAJHZ-UHFFFAOYSA-N 50500042 CHEMBL3740218 DNA gyrase subunit B 16410 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500042&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127040042 433911943 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216834 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(Cl)cc3)c2c1 InChI=1S/C22H24ClN5O2S/c1-30-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(31)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,31) JHIAAASMABSHJU-UHFFFAOYSA-N 50500043 CHEMBL3741186 DNA gyrase subunit B 12840 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500043&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127040066 433911944 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216835 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccccc3)c2c1 InChI=1S/C22H25N5O2S/c1-29-18-15-20-19(23-16-18)7-8-21(28)27(20)14-11-25-9-12-26(13-10-25)22(30)24-17-5-3-2-4-6-17/h2-8,15-16H,9-14H2,1H3,(H,24,30) BUVRVJDFIRQRHD-UHFFFAOYSA-N 50500044 CHEMBL3740389 DNA gyrase subunit B 15410 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500044&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039727 433911945 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216836 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(Br)cc3)c2c1 InChI=1S/C22H24BrN5O3/c1-31-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(30)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,30) DIRYYEVNHVOPET-UHFFFAOYSA-N 50500045 CHEMBL3741294 DNA gyrase subunit B 750 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500045&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039725 433911946 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216837 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(Cl)cc3)c2c1 InChI=1S/C22H24ClN5O3/c1-31-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(30)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,30) ZPEZLPJGHTVKPP-UHFFFAOYSA-N 50500046 CHEMBL3742062 DNA gyrase subunit B 320 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500046&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042673 433911947 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216838 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(cc3)C(C)=O)c2c1 InChI=1S/C24H27N5O4/c1-17(30)18-3-5-19(6-4-18)26-24(32)28-12-9-27(10-13-28)11-14-29-22-15-20(33-2)16-25-21(22)7-8-23(29)31/h3-8,15-16H,9-14H2,1-2H3,(H,26,32) GCXVZVBLYWPNMU-UHFFFAOYSA-N 50500047 CHEMBL3739873 DNA gyrase subunit B 19400 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500047&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042674 433911948 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216839 COc1cnc2ccc(=O)n(CCN3CCN(Cc4ccc(cc4)[N+]([O-])=O)CC3)c2c1 InChI=1S/C22H25N5O4/c1-31-19-14-21-20(23-15-19)6-7-22(28)26(21)13-12-24-8-10-25(11-9-24)16-17-2-4-18(5-3-17)27(29)30/h2-7,14-15H,8-13,16H2,1H3 LTCNTWXXZFEBRS-UHFFFAOYSA-N 50500048 CHEMBL3739454 DNA gyrase subunit B 980 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500048&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042370 433911949 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216840 COc1cnc2ccc(=O)n(CCN3CCN(Cc4ccccc4)CC3)c2c1 InChI=1S/C22H26N4O2/c1-28-19-15-21-20(23-16-19)7-8-22(27)26(21)14-13-24-9-11-25(12-10-24)17-18-5-3-2-4-6-18/h2-8,15-16H,9-14,17H2,1H3 MUDGQNZCMSDDIP-UHFFFAOYSA-N 50500049 CHEMBL3741497 DNA gyrase subunit B 940 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500049&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039739 433911950 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216841 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(Br)cc3)c2c1 InChI=1S/C22H24BrN5O2S/c1-30-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(31)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,31) XYBNTIJUBJFFOQ-UHFFFAOYSA-N 50500050 CHEMBL3741396 DNA gyrase subunit B 490 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500050&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042005 433911951 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216842 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=S)Nc3ccc(F)cc3)c2c1 InChI=1S/C22H24FN5O2S/c1-30-18-14-20-19(24-15-18)6-7-21(29)28(20)13-10-26-8-11-27(12-9-26)22(31)25-17-4-2-16(23)3-5-17/h2-7,14-15H,8-13H2,1H3,(H,25,31) JOPVXRYPAOOMDI-UHFFFAOYSA-N 50500051 CHEMBL3741244 DNA gyrase subunit B 14660 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500051&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127040065 433911952 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216843 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(cc3)[N+]([O-])=O)c2c1 InChI=1S/C22H24N6O5/c1-33-18-14-20-19(23-15-18)6-7-21(29)27(20)13-10-25-8-11-26(12-9-25)22(30)24-16-2-4-17(5-3-16)28(31)32/h2-7,14-15H,8-13H2,1H3,(H,24,30) LDICWXCQDGHOFG-UHFFFAOYSA-N 50500052 CHEMBL3740531 DNA gyrase subunit B 290 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500052&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039724 433911953 C02125 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216844 COc1cnc2ccc(=O)n(CCN3CCN(Cc4ccc(Br)cc4)CC3)c2c1 InChI=1S/C22H25BrN4O2/c1-29-19-14-21-20(24-15-19)6-7-22(28)27(21)13-12-25-8-10-26(11-9-25)16-17-2-4-18(23)5-3-17/h2-7,14-15H,8-13,16H2,1H3 DYKYIGDPWLDUBW-UHFFFAOYSA-N 50500053 CHEMBL3741142 DNA gyrase subunit B 6440 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500053&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127042706 433911954 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216845 COc1cnc2ccc(=O)n(CCN3CCN(Cc4ccc(F)cc4)CC3)c2c1 InChI=1S/C22H25FN4O2/c1-29-19-14-21-20(24-15-19)6-7-22(28)27(21)13-12-25-8-10-26(11-9-25)16-17-2-4-18(23)5-3-17/h2-7,14-15H,8-13,16H2,1H3 ARDDDECUUZZLNM-UHFFFAOYSA-N 50500054 CHEMBL3742364 DNA gyrase subunit B 910 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500054&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127040080 433911955 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216846 COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin DNA gyrase subunit B 11200 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366824&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search MFX 4Z3O,4Z2C,5CDQ,2XKK,5BS8,3FOF,5BTA 152946 160845926 63611 DB00218 C07663 ZINC03826253 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51216847 COc1cnc2ccc(=O)n(CCN3CCN(CC3)C(=O)Nc3ccc(C)cc3)c2c1 InChI=1S/C23H27N5O3/c1-17-3-5-18(6-4-17)25-23(30)27-12-9-26(10-13-27)11-14-28-21-15-19(31-2)16-24-20(21)7-8-22(28)29/h3-8,15-16H,9-14H2,1-2H3,(H,25,30) CGZWZKGXKDXSRX-UHFFFAOYSA-N 50500055 CHEMBL3740743 DNA gyrase subunit B 2680 ChEMBL 10.1016/j.bmc.2015.11.039 10.7270/Q25T3PG4 26678175 Bobesh, KA; Renuka, J; Srilakshmi, RR; Yellanki, S; Kulkarni, P; Yogeeswari, P; Sriram, D Birla Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500055&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127039726 433911956 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218336 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccc(C)cc23)cc1 InChI=1S/C27H23N3O2S/c1-18-7-14-22(15-8-18)33(31,32)30-21-12-10-20(11-13-21)28-27-23-5-3-4-6-25(23)29-26-16-9-19(2)17-24(26)27/h3-17,30H,1-2H3,(H,28,29) HSUFAVMAYZXGBV-UHFFFAOYSA-N 50500615 CHEMBL3753841 DNA gyrase subunit B 9800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500615&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036796 433912516 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218337 Clc1ccc2nc3ccccc3c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c2c1 InChI=1S/C26H19ClN4O/c27-17-10-15-24-22(16-17)25(21-8-4-5-9-23(21)31-24)28-19-11-13-20(14-12-19)30-26(32)29-18-6-2-1-3-7-18/h1-16H,(H,28,31)(H2,29,30,32) LBOPRXXFTOYTIV-UHFFFAOYSA-N 50500616 CHEMBL3752017 DNA gyrase subunit B 23600 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500616&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029483 433912517 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218338 Cc1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C27H21ClN4O/c1-17-6-9-20(10-7-17)30-27(33)31-21-13-11-19(12-14-21)29-26-22-4-2-3-5-24(22)32-25-15-8-18(28)16-23(25)26/h2-16H,1H3,(H,29,32)(H2,30,31,33) DKACDESSEAPFHP-UHFFFAOYSA-N 50500617 CHEMBL3751882 DNA gyrase subunit B 12500 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500617&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029790 433912518 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218339 Clc1ccc2nc3ccccc3c(Nc3ccc(NS(=O)(=O)c4ccccc4)cc3)c2c1 InChI=1S/C25H18ClN3O2S/c26-17-10-15-24-22(16-17)25(21-8-4-5-9-23(21)28-24)27-18-11-13-19(14-12-18)29-32(30,31)20-6-2-1-3-7-20/h1-16,29H,(H,27,28) YNCOXQOAERCIRH-UHFFFAOYSA-N 50500618 CHEMBL3752724 DNA gyrase subunit B 9200 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500618&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036797 433912519 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218340 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccc(Cl)cc23)cc1 InChI=1S/C25H17ClN4O4S/c26-16-5-14-24-22(15-16)25(21-3-1-2-4-23(21)28-24)27-17-6-8-18(9-7-17)29-35(33,34)20-12-10-19(11-13-20)30(31)32/h1-15,29H,(H,27,28) XRQGCYGXORPVFM-UHFFFAOYSA-N 50500619 CHEMBL3752450 DNA gyrase subunit B 8100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500619&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127037609 433912520 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218341 O=S(=O)(Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1)c1ccccc1 InChI=1S/C25H19N3O2S/c29-31(30,20-8-2-1-3-9-20)28-19-16-14-18(15-17-19)26-25-21-10-4-6-12-23(21)27-24-13-7-5-11-22(24)25/h1-17,28H,(H,26,27) NJONKTQXERJMCB-UHFFFAOYSA-N 50500620 CHEMBL48931 DNA gyrase subunit B 15100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500620&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 148794 433912521 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218342 Clc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 InChI=1S/C25H18ClN3O2S/c26-17-9-15-20(16-10-17)32(30,31)29-19-13-11-18(12-14-19)27-25-21-5-1-3-7-23(21)28-24-8-4-2-6-22(24)25/h1-16,29H,(H,27,28) DZEHKFZAYZKAIR-UHFFFAOYSA-N 50500621 CHEMBL3752604 DNA gyrase subunit B 23800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500621&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036965 433912522 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218343 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 InChI=1S/C25H18N4O4S/c30-29(31)19-13-15-20(16-14-19)34(32,33)28-18-11-9-17(10-12-18)26-25-21-5-1-3-7-23(21)27-24-8-4-2-6-22(24)25/h1-16,28H,(H,26,27) VRRWDNDZGBFDKF-UHFFFAOYSA-N 50500622 CHEMBL3753115 DNA gyrase subunit B 22400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500622&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036966 433912523 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218344 Cc1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccc(C)cc34)cc2)cc1 InChI=1S/C28H24N4S/c1-18-7-10-21(11-8-18)30-28(33)31-22-14-12-20(13-15-22)29-27-23-5-3-4-6-25(23)32-26-16-9-19(2)17-24(26)27/h3-17H,1-2H3,(H,29,32)(H2,30,31,33) OEOFHRKSLMFEHQ-UHFFFAOYSA-N 50500623 CHEMBL3753765 DNA gyrase subunit B 26900 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500623&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036023 433912524 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218345 Clc1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C26H18Cl2N4S/c27-16-5-8-19(9-6-16)30-26(33)31-20-12-10-18(11-13-20)29-25-21-3-1-2-4-23(21)32-24-14-7-17(28)15-22(24)25/h1-15H,(H,29,32)(H2,30,31,33) HFEXYIDUQRZWPX-UHFFFAOYSA-N 50500624 CHEMBL3751975 DNA gyrase subunit B 31500 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500624&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036860 433912525 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218346 [O-][N+](=O)c1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C26H18ClN5O2S/c27-16-5-14-24-22(15-16)25(21-3-1-2-4-23(21)31-24)28-17-6-8-18(9-7-17)29-26(35)30-19-10-12-20(13-11-19)32(33)34/h1-15H,(H,28,31)(H2,29,30,35) FEBUZZAGFFFQHM-UHFFFAOYSA-N 50500625 CHEMBL3752396 DNA gyrase subunit B 28800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500625&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036861 433912526 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218347 Cc1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C27H21ClN4S/c1-17-6-9-20(10-7-17)30-27(33)31-21-13-11-19(12-14-21)29-26-22-4-2-3-5-24(22)32-25-15-8-18(28)16-23(25)26/h2-16H,1H3,(H,29,32)(H2,30,31,33) DXRFCBBMIOWWGE-UHFFFAOYSA-N 50500626 CHEMBL3754162 DNA gyrase subunit B 33900 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500626&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036862 433912527 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218348 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=O)Nc4ccc(cc4)[N+]([O-])=O)cc3)c2c1 InChI=1S/C27H21N5O3/c1-17-6-15-25-23(16-17)26(22-4-2-3-5-24(22)31-25)28-18-7-9-19(10-8-18)29-27(33)30-20-11-13-21(14-12-20)32(34)35/h2-16H,1H3,(H,28,31)(H2,29,30,33) XIZZMXLHWBEEBA-UHFFFAOYSA-N 50500627 CHEMBL3752277 DNA gyrase subunit B 7400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500627&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029481 433912528 C02125 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218349 Cc1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccc(C)cc34)cc2)cc1 InChI=1S/C28H24N4O/c1-18-7-10-21(11-8-18)30-28(33)31-22-14-12-20(13-15-22)29-27-23-5-3-4-6-25(23)32-26-16-9-19(2)17-24(26)27/h3-17H,1-2H3,(H,29,32)(H2,30,31,33) SEIMXPKAFOZMFT-UHFFFAOYSA-N 50500628 CHEMBL3753968 DNA gyrase subunit B 29600 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500628&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029482 433912529 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218350 Clc1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C26H18Cl2N4O/c27-16-5-8-19(9-6-16)30-26(33)31-20-12-10-18(11-13-20)29-25-21-3-1-2-4-23(21)32-24-14-7-17(28)15-22(24)25/h1-15H,(H,29,32)(H2,30,31,33) XIHLZVBEUGXADQ-UHFFFAOYSA-N 50500629 CHEMBL3754374 DNA gyrase subunit B 11800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500629&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029788 433912530 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218351 O=C(Nc1ccccc1)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 InChI=1S/C26H20N4O/c31-26(28-18-8-2-1-3-9-18)29-20-16-14-19(15-17-20)27-25-21-10-4-6-12-23(21)30-24-13-7-5-11-22(24)25/h1-17H,(H,27,30)(H2,28,29,31) GZNSAGOUDBUPIM-UHFFFAOYSA-N 50500630 CHEMBL49272 DNA gyrase subunit B 32600 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500630&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 149541 433912531 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218352 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-N 50226181 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyl-tetrahydro-2H-pyran-4-yl carbamate::CHEMBL36506::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid (3R,4S,5R,6R)-5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(4-methyl-pent-3-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester::Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-3-(3-methyl-but-2-enyl)-benzoylamino]-8-methyl-2-oxo-2H-chromen-7-yloxy}-3-methoxy-2,2-dimethyl-tetrahydro-pyran-4-yl ester(Novobiocin)::NOVOBIOCIN DNA gyrase subunit B 46 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226181&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NOV 1AJ6,4URO,4URN,1S14,7PTF,1KIJ,6B89,3LPS,6Y8O,6Y8L,7PQI,6TBE,6MIT 54675769 104097057 28368 CHEMBL36506 DB01051 C05080 ZINC14879999 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218353 NNC(=O)c1ccncc1 InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10) QRXWMOHMRWLFEY-UHFFFAOYSA-N 50336507 4-pyridinecarbohydrazide(Isoniazid)::CHEMBL64::Dow-isoniazid::Hyzyd::INH::ISONICOTINIC ACID HYDRAZIDE(ISONIAZIDE)::Isoniazid (INH)::Isonicotinic acid hydrazide (Isoniazid)::Isonicotinic acid hydrazide(Isoniazid)::Isonicotinylhydrazine::Laniazid::Nydrazid::Rimifon::Stanozide::isoniazid::isonicotinamide::isonicotinhydrazide::isonicotinohydrazide::isonicotinyl hydrazide::pyridine-4-carbohydrazide DNA gyrase subunit B >50000 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336507&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search NIZ 3WXO,5KT8,5SYJ,5SYI,5SXQ,5SXS,5SXT,5KSN,5KSG,6CDQ,4PAE,6CFQ 3767 125086609 6030 CHEMBL64 DB00951 C07054 ZINC00001590 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218354 CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 50370232 BA-41166E::L-5103::RIFAMPIN::Rifadin::Rifampicin DNA gyrase subunit B >50000 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370232&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search RFP 1SKX,2HW2,1YNN,6BRD,5HV1,5UHG,5UHD,5UHB,5UHC,5UH6,5KOX,7SZJ,6CCV,6BED,5UAH,5UAL,5UAC,3AOB,3AOD,1I6V,4KMU 5381226 160849334 28077 DB01045 C06688 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218355 Clc1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C26H19ClN4S/c27-17-9-11-19(12-10-17)29-26(32)30-20-15-13-18(14-16-20)28-25-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)25/h1-16H,(H,28,31)(H2,29,30,32) CAEWAICUGNOBDH-UHFFFAOYSA-N 50500631 CHEMBL3752620 DNA gyrase subunit B 8400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500631&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027598 433912532 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218356 Cc1ccc2nc3ccccc3c(Nc3ccc(NS(=O)(=O)c4ccc(Cl)cc4)cc3)c2c1 InChI=1S/C26H20ClN3O2S/c1-17-6-15-25-23(16-17)26(22-4-2-3-5-24(22)29-25)28-19-9-11-20(12-10-19)30-33(31,32)21-13-7-18(27)8-14-21/h2-16,30H,1H3,(H,28,29) GKZKKBZXUWSTQI-UHFFFAOYSA-N 50500632 CHEMBL3752152 DNA gyrase subunit B 5210 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500632&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036754 433912533 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218357 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=S)Nc4ccc(Cl)cc4)cc3)c2c1 InChI=1S/C27H21ClN4S/c1-17-6-15-25-23(16-17)26(22-4-2-3-5-24(22)32-25)29-19-11-13-21(14-12-19)31-27(33)30-20-9-7-18(28)8-10-20/h2-16H,1H3,(H,29,32)(H2,30,31,33) ITWNOUZZGFFRAQ-UHFFFAOYSA-N 50500633 CHEMBL3753770 DNA gyrase subunit B 11200 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500633&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036968 433912534 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218358 Cc1ccc2nc3ccccc3c(Nc3ccc(NS(=O)(=O)c4ccc(cc4)[N+]([O-])=O)cc3)c2c1 InChI=1S/C26H20N4O4S/c1-17-6-15-25-23(16-17)26(22-4-2-3-5-24(22)28-25)27-18-7-9-19(10-8-18)29-35(33,34)21-13-11-20(12-14-21)30(31)32/h2-16,29H,1H3,(H,27,28) UYIYVUGIIXAKRQ-UHFFFAOYSA-N 50500634 CHEMBL3754554 DNA gyrase subunit B 8340 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500634&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036795 433912535 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218359 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 InChI=1S/C26H21N3O2S/c1-18-10-16-21(17-11-18)32(30,31)29-20-14-12-19(13-15-20)27-26-22-6-2-4-8-24(22)28-25-9-5-3-7-23(25)26/h2-17,29H,1H3,(H,27,28) TUBFFHNGKOTETL-UHFFFAOYSA-N 50500635 CHEMBL3752318 DNA gyrase subunit B 9300 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500635&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 625123 433912536 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218360 Clc1ccc2nc3ccccc3c(Nc3ccc(NC(=S)Nc4ccccc4)cc3)c2c1 InChI=1S/C26H19ClN4S/c27-17-10-15-24-22(16-17)25(21-8-4-5-9-23(21)31-24)28-19-11-13-20(14-12-19)30-26(32)29-18-6-2-1-3-7-18/h1-16H,(H,28,31)(H2,29,30,32) ARTCIEMZDLOYBF-UHFFFAOYSA-N 50500636 CHEMBL3752104 DNA gyrase subunit B 29300 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500636&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036024 433912537 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218361 S=C(Nc1ccccc1)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 InChI=1S/C26H20N4S/c31-26(28-18-8-2-1-3-9-18)29-20-16-14-19(15-17-20)27-25-21-10-4-6-12-23(21)30-24-13-7-5-11-22(24)25/h1-17H,(H,27,30)(H2,28,29,31) UPZKVGADTRAZJM-UHFFFAOYSA-N 50500637 CHEMBL3754757 DNA gyrase subunit B 8200 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500637&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027597 433912538 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218362 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=O)Nc4ccc(Cl)cc4)cc3)c2c1 InChI=1S/C27H21ClN4O/c1-17-6-15-25-23(16-17)26(22-4-2-3-5-24(22)32-25)29-19-11-13-21(14-12-19)31-27(33)30-20-9-7-18(28)8-10-20/h2-16H,1H3,(H,29,32)(H2,30,31,33) DJDNTQARZWPUGC-UHFFFAOYSA-N 50500638 CHEMBL3753253 DNA gyrase subunit B 11400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500638&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027934 433912539 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218363 [O-][N+](=O)c1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccc(Cl)cc34)cc2)cc1 InChI=1S/C26H18ClN5O3/c27-16-5-14-24-22(15-16)25(21-3-1-2-4-23(21)31-24)28-17-6-8-18(9-7-17)29-26(33)30-19-10-12-20(13-11-19)32(34)35/h1-15H,(H,28,31)(H2,29,30,33) BEKGNZRTWLSMTA-UHFFFAOYSA-N 50500639 CHEMBL3754191 DNA gyrase subunit B 7300 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500639&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127029789 433912540 C02125 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218364 [O-][N+](=O)c1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C26H19N5O3/c32-26(29-19-13-15-20(16-14-19)31(33)34)28-18-11-9-17(10-12-18)27-25-21-5-1-3-7-23(21)30-24-8-4-2-6-22(24)25/h1-16H,(H,27,30)(H2,28,29,32) FRBICWAQKKWVMX-UHFFFAOYSA-N 50500640 CHEMBL3753644 DNA gyrase subunit B 26800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500640&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127026665 433912541 C02125 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218365 COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin DNA gyrase subunit B 11200 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366824&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search MFX 4Z3O,4Z2C,5CDQ,2XKK,5BS8,3FOF,5BTA 152946 160845926 63611 DB00218 C07663 ZINC03826253 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218366 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=S)Nc4ccccc4)cc3)c2c1 InChI=1S/C27H22N4S/c1-18-11-16-25-23(17-18)26(22-9-5-6-10-24(22)31-25)28-20-12-14-21(15-13-20)30-27(32)29-19-7-3-2-4-8-19/h2-17H,1H3,(H,28,31)(H2,29,30,32) PWRIYJNBFDWROG-UHFFFAOYSA-N 50500641 CHEMBL3754465 DNA gyrase subunit B 6300 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500641&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036967 433912542 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218367 Cc1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C27H22N4O/c1-18-10-12-20(13-11-18)29-27(32)30-21-16-14-19(15-17-21)28-26-22-6-2-4-8-24(22)31-25-9-5-3-7-23(25)26/h2-17H,1H3,(H,28,31)(H2,29,30,32) IJLQLEZTNLHOGG-UHFFFAOYSA-N 50500642 CHEMBL3753099 DNA gyrase subunit B 13100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500642&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127026666 433912543 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218368 Cc1ccc2nc3ccccc3c(Nc3ccc(NS(=O)(=O)c4ccccc4)cc3)c2c1 InChI=1S/C26H21N3O2S/c1-18-11-16-25-23(17-18)26(22-9-5-6-10-24(22)28-25)27-19-12-14-20(15-13-19)29-32(30,31)21-7-3-2-4-8-21/h2-17,29H,1H3,(H,27,28) KTHWDYXVQLXNIP-UHFFFAOYSA-N 50500643 CHEMBL3752188 DNA gyrase subunit B 5860 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500643&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036753 433912544 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218369 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)c2c1 InChI=1S/C27H22N4O/c1-18-11-16-25-23(17-18)26(22-9-5-6-10-24(22)31-25)28-20-12-14-21(15-13-20)30-27(32)29-19-7-3-2-4-8-19/h2-17H,1H3,(H,28,31)(H2,29,30,32) DWEIKWRGOCAUOQ-UHFFFAOYSA-N 50500644 CHEMBL3752568 DNA gyrase subunit B 22100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500644&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027601 433912545 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218370 Cc1ccc2nc3ccccc3c(Nc3ccc(NC(=S)Nc4ccc(cc4)[N+]([O-])=O)cc3)c2c1 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MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218371 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccc(Cl)cc23)cc1 InChI=1S/C26H20ClN3O2S/c1-17-6-13-21(14-7-17)33(31,32)30-20-11-9-19(10-12-20)28-26-22-4-2-3-5-24(22)29-25-15-8-18(27)16-23(25)26/h2-16,30H,1H3,(H,28,29) ONYUSSCCVWBBQM-UHFFFAOYSA-N 50500646 CHEMBL3753399 DNA gyrase subunit B 22800 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500646&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127037610 433912547 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218372 Cc1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C27H22N4S/c1-18-10-12-20(13-11-18)29-27(32)30-21-16-14-19(15-17-21)28-26-22-6-2-4-8-24(22)31-25-9-5-3-7-23(25)26/h2-17H,1H3,(H,28,31)(H2,29,30,32) PRTLOTIFUABFLU-UHFFFAOYSA-N 50500647 CHEMBL3754614 DNA gyrase subunit B 31100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500647&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027600 433912548 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218373 Clc1ccc(NC(=O)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C26H19ClN4O/c27-17-9-11-19(12-10-17)29-26(32)30-20-15-13-18(14-16-20)28-25-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)25/h1-16H,(H,28,31)(H2,29,30,32) WIPNHPBSPZCVTE-UHFFFAOYSA-N 50500648 CHEMBL3753342 DNA gyrase subunit B 10400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500648&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127026664 433912549 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218374 Clc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2c3ccccc3nc3ccc(Cl)cc23)cc1 InChI=1S/C25H17Cl2N3O2S/c26-16-5-12-20(13-6-16)33(31,32)30-19-10-8-18(9-11-19)28-25-21-3-1-2-4-23(21)29-24-14-7-17(27)15-22(24)25/h1-15,30H,(H,28,29) YJGYHHRJSQPSRR-UHFFFAOYSA-N 50500649 CHEMBL3753557 DNA gyrase subunit B 12400 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500649&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127036798 433912550 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51218375 [O-][N+](=O)c1ccc(NC(=S)Nc2ccc(Nc3c4ccccc4nc4ccccc34)cc2)cc1 InChI=1S/C26H19N5O2S/c32-31(33)20-15-13-19(14-16-20)29-26(34)28-18-11-9-17(10-12-18)27-25-21-5-1-3-7-23(21)30-24-8-4-2-6-22(24)25/h1-16H,(H,27,30)(H2,28,29,34) RCTFXEQSKCLSDZ-UHFFFAOYSA-N 50500650 CHEMBL3752361 DNA gyrase subunit B 13100 ChEMBL 10.1016/j.bmc.2016.01.011 10.7270/Q2MP5682 26787274 Medapi, B; Meda, N; Kulkarni, P; Yogeeswari, P; Sriram, D Institute of Technology & Science-Pilani http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500650&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 127027599 433912551 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265779 CO\N=C1\C(=O)N(Cc2cn(CC(=O)N3CCC[C@@H]4CN(C[C@H]34)c3c(F)cc4c(c3OC)n(cc(C(O)=O)c4=O)C3CC3)nn2)c2ccccc12 InChI=1S/C35H35FN8O7/c1-50-33-30-23(32(46)24(35(48)49)16-43(30)21-9-10-21)12-25(36)31(33)40-13-19-6-5-11-42(27(19)17-40)28(45)18-41-14-20(37-39-41)15-44-26-8-4-3-7-22(26)29(34(44)47)38-51-2/h3-4,7-8,12,14,16,19,21,27H,5-6,9-11,13,15,17-18H2,1-2H3,(H,48,49)/b38-29+/t19-,27+/m1/s1 QXBSNNSZCRTRGC-JLJGQEHPSA-N 50516944 CHEMBL4438262 DNA gyrase subunit B 8580 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516944&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 155513029 440725526 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265780 COc1c(N2C[C@H]3CCCN([C@H]3C2)C(=O)Cn2cc(CN3C(=O)\C(=N\NC(N)=S)c4cc(F)ccc34)nn2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C35H34F2N10O6S/c1-53-32-29-22(31(49)23(34(51)52)14-46(29)20-5-6-20)10-24(37)30(32)43-11-17-3-2-8-45(26(17)15-43)27(48)16-44-12-19(39-42-44)13-47-25-7-4-18(36)9-21(25)28(33(47)50)40-41-35(38)54/h4,7,9-10,12,14,17,20,26H,2-3,5-6,8,11,13,15-16H2,1H3,(H,51,52)(H3,38,41,54)/b40-28+/t17-,26+/m1/s1 CFJXZCSATKMNMB-WKKWFYDSSA-N 50516945 CHEMBL4446054 DNA gyrase subunit B 10500 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516945&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 155518215 440725527 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265781 COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 50366824 Avelox::MOXIFLOXACIN::Moxifl-oxacin DNA gyrase subunit B 13700 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366824&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search MFX 4Z3O,4Z2C,5CDQ,2XKK,5BS8,3FOF,5BTA 152946 160845926 63611 DB00218 C07663 ZINC03826253 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265782 COc1c(N2C[C@H]3CCCN([C@H]3C2)C(=O)Cn2cc(CN3C(=O)C(=O)c4ccccc34)nn2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C34H32FN7O7/c1-49-32-28-22(30(44)23(34(47)48)15-41(28)20-8-9-20)11-24(35)29(32)38-12-18-5-4-10-40(26(18)16-38)27(43)17-39-13-19(36-37-39)14-42-25-7-3-2-6-21(25)31(45)33(42)46/h2-3,6-7,11,13,15,18,20,26H,4-5,8-10,12,14,16-17H2,1H3,(H,47,48)/t18-,26+/m1/s1 FHBUITBJKXGEHE-DWXRJYCRSA-N 50516946 CHEMBL4549350 DNA gyrase subunit B 5970 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516946&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 155550457 440725528 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265783 COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) XUBOMFCQGDBHNK-UHFFFAOYSA-N 50117914 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid::1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::AM 1155::CHEMBL31::GATIFLOXACIN DNA gyrase subunit B 13300 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117914&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search GFN 7F35,5BTD,5BTF 5379 104011321 5280 CHEMBL31 DB01044 C07661 ZINC38197764 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51265784 COc1c(N2C[C@H]3CCCN([C@H]3C2)C(=O)Cn2cc(CN3C(=O)\C(=N\NC(N)=S)c4ccccc34)nn2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 InChI=1S/C35H35FN10O6S/c1-52-32-29-22(31(48)23(34(50)51)15-45(29)20-8-9-20)11-24(36)30(32)42-12-18-5-4-10-44(26(18)16-42)27(47)17-43-13-19(38-41-43)14-46-25-7-3-2-6-21(25)28(33(46)49)39-40-35(37)53/h2-3,6-7,11,13,15,18,20,26H,4-5,8-10,12,14,16-17H2,1H3,(H,50,51)(H3,37,40,53)/b39-28+/t18-,26+/m1/s1 QZGCFIRSKKELGM-GAGALPAKSA-N 50516947 CHEMBL4441945 DNA gyrase subunit B 6730 ChEMBL 10.1016/j.ejmech.2019.07.057 10.7270/Q2639T36 31352245 Gao, F; Chen, Z; Ma, L; Fan, Y; Chen, L; Lu, G Medical School of Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516947&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 155515688 440725529 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51238401 OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24) MYSWGUAQZAJSOK-UHFFFAOYSA-N 21690 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid::1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid::Bay 09867::CHEMBL8::Ciprinol::Cipro::Ciprofloxacin::US11590142, Compound Ciprofloxacin::US9138393, Ciprofloxacin HCl::US9144538, Ciprofloxacin HCl DNA gyrase subunit B 10600 ChEMBL 10.1016/j.ejmech.2018.10.031 10.7270/Q28D00KV 30384044 Carta, A; Bua, A; Corona, P; Piras, S; Briguglio, I; Molicotti, P; Zanetti, S; Laurini, E; Aulic, S; Fermeglia, M; Pricl, S University of Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21690&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search CPF 1OYE,2XCT,4KRA,4BVV,1T9U,5BTC 2764 49700797 100241 CHEMBL8 DB00537 C05349 ZINC00020220 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51238402 COc1cc2c([nH]cc(C(O)=O)c2=O)c2nnn(C)c12 InChI=1S/C12H10N4O4/c1-16-10-7(20-2)3-5-8(9(10)14-15-16)13-4-6(11(5)17)12(18)19/h3-4H,1-2H3,(H,13,17)(H,18,19) OHDONGVYMZAHMS-UHFFFAOYSA-N 50506875 CHEMBL4443084 DNA gyrase subunit B 91300 ChEMBL 10.1016/j.ejmech.2018.10.031 10.7270/Q28D00KV 30384044 Carta, A; Bua, A; Corona, P; Piras, S; Briguglio, I; Molicotti, P; Zanetti, S; Laurini, E; Aulic, S; Fermeglia, M; Pricl, S University of Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50506875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50506875&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 146000158 440715460 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51238403 COc1cc2c(n(C)cc(C(O)=O)c2=O)c2nnn(C)c12 InChI=1S/C13H12N4O4/c1-16-5-7(13(19)20)12(18)6-4-8(21-3)11-9(10(6)16)14-15-17(11)2/h4-5H,1-3H3,(H,19,20) GCHPGNPBZRNGQG-UHFFFAOYSA-N 50506876 CHEMBL4580793 DNA gyrase subunit B 27600 ChEMBL 10.1016/j.ejmech.2018.10.031 10.7270/Q28D00KV 30384044 Carta, A; Bua, A; Corona, P; Piras, S; Briguglio, I; Molicotti, P; Zanetti, S; Laurini, E; Aulic, S; Fermeglia, M; Pricl, S University of Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50506876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50506876&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 146001230 440715461 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51238404 CCOc1cc2c(n(C)cc(C(O)=O)c2=O)c2nnn(C)c12 InChI=1S/C14H14N4O4/c1-4-22-9-5-7-11(10-12(9)18(3)16-15-10)17(2)6-8(13(7)19)14(20)21/h5-6H,4H2,1-3H3,(H,20,21) TVUJHDNYPHWOLR-UHFFFAOYSA-N 50506877 CHEMBL4545571 DNA gyrase subunit B 28200 ChEMBL 10.1016/j.ejmech.2018.10.031 10.7270/Q28D00KV 30384044 Carta, A; Bua, A; Corona, P; Piras, S; Briguglio, I; Molicotti, P; Zanetti, S; Laurini, E; Aulic, S; Fermeglia, M; Pricl, S University of Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50506877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50506877&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 145999280 440715462 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51505857 COc1ccc2cc(-n3cc(COc4nc(sc4C(N)=O)-c4ccccn4)nn3)c(=O)oc2c1 InChI=1S/C22H16N6O5S/c1-31-14-6-5-12-8-16(22(30)33-17(12)9-14)28-10-13(26-27-28)11-32-20-18(19(23)29)34-21(25-20)15-4-2-3-7-24-15/h2-10H,11H2,1H3,(H2,23,29) BBEMZDCANZHGAH-UHFFFAOYSA-N 50606698 CHEMBL5220158 DNA gyrase subunit B 500 ChEMBL 10.7270/Q2377DTB 35597009 Sharma, A; Agrahari, AK; Rajkhowa, S; Tiwari, VK Barauni (A Constituent Unit of Lalit Narayan Mithila University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606698&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 168299315 482617549 1 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51503097 C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2CC[C@H](O)C2)C(=O)NC(=O)NC1=O InChI=1S/C22H24FN5O6/c1-9-7-28-15-11(5-13-16(14(15)23)34-26-18(13)27-4-3-12(29)8-27)6-22(17(28)10(2)33-9)19(30)24-21(32)25-20(22)31/h5,9-10,12,17,29H,3-4,6-8H2,1-2H3,(H2,24,25,30,31,32)/t9-,10+,12+,17-/m1/s1 PVUVIUPGXCPBQR-YFEKEUHLSA-N 50605620 CHEMBL5201644 DNA gyrase subunit B 20000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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51503098 C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2C[C@@H](O)[C@H](O)C2)C(=O)NC(=O)NC1=O InChI=1S/C22H24FN5O7/c1-8-5-28-15-10(4-22(17(28)9(2)34-8)19(31)24-21(33)25-20(22)32)3-11-16(14(15)23)35-26-18(11)27-6-12(29)13(30)7-27/h3,8-9,12-13,17,29-30H,4-7H2,1-2H3,(H2,24,25,31,32,33)/t8-,9+,12-,13-,17-/m1/s1 JNWGENNSMMYTDJ-ZGZNMHKISA-N 50605621 CHEMBL5206134 DNA gyrase subunit B 16000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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51503099 CO[C@H]1CCN(C1)c1noc2c(F)c3N4C[C@@H](C)O[C@@H](C)[C@@H]4C4(Cc3cc12)C(=O)NC(=O)NC4=O InChI=1S/C23H26FN5O6/c1-10-8-29-16-12(7-23(18(29)11(2)34-10)20(30)25-22(32)26-21(23)31)6-14-17(15(16)24)35-27-19(14)28-5-4-13(9-28)33-3/h6,10-11,13,18H,4-5,7-9H2,1-3H3,(H2,25,26,30,31,32)/t10-,11+,13+,18-/m1/s1 CPXPEOKQLULRLW-KACXOKKCSA-N 50605624 CHEMBL5179981 DNA gyrase subunit B 77000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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51503100 C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2CC[C@H](CO)C2)C(=O)NC(=O)NC1=O InChI=1S/C23H26FN5O6/c1-10-7-29-16-13(6-23(18(29)11(2)34-10)20(31)25-22(33)26-21(23)32)5-14-17(15(16)24)35-27-19(14)28-4-3-12(8-28)9-30/h5,10-12,18,30H,3-4,6-9H2,1-2H3,(H2,25,26,31,32,33)/t10-,11+,12+,18-/m1/s1 OMHMOGGZFVZYON-XBQNPMMNSA-N 50605625 CHEMBL5185015 DNA gyrase subunit B 18000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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51503101 C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2CC[C@H](N)C2)C(=O)NC(=O)NC1=O InChI=1S/C22H25FN6O5/c1-9-7-29-15-11(5-13-16(14(15)23)34-27-18(13)28-4-3-12(24)8-28)6-22(17(29)10(2)33-9)19(30)25-21(32)26-20(22)31/h5,9-10,12,17H,3-4,6-8,24H2,1-2H3,(H2,25,26,30,31,32)/t9-,10+,12+,17-/m1/s1 KPQGBZXQANBYBP-YFEKEUHLSA-N 50605626 CHEMBL5173922 DNA gyrase subunit B 34000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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51503102 C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2CC[C@@H](C2)C#N)C(=O)NC(=O)NC1=O InChI=1S/C23H23FN6O5/c1-10-8-30-16-13(6-23(18(30)11(2)34-10)20(31)26-22(33)27-21(23)32)5-14-17(15(16)24)35-28-19(14)29-4-3-12(7-25)9-29/h5,10-12,18H,3-4,6,8-9H2,1-2H3,(H2,26,27,31,32,33)/t10-,11+,12-,18-/m1/s1 SQJWPXKUJFKAQG-QPSSLKIMSA-N 50605627 CHEMBL5186061 DNA gyrase subunit B 10000 ChEMBL 10.7270/Q2C251HR 35500229 Govender, P; Müller, R; Singh, K; Reddy, V; Eyermann, CJ; Fienberg, S; Ghorpade, SR; Koekemoer, L; Myrick, A; Schnappinger, D; Engelhart, C; Meshanni, J; Byl, JAW; Osheroff, N; Singh, V; Chibale, K; Basarab, GS University of Cape Town http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50605627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 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MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51512156 [O-][N+](=O)c1ccc2sc(nc(=O)c2c1)N1CCN(CC1)C(=S)Nc1ccccc1 InChI=1S/C19H17N5O3S2/c25-17-15-12-14(24(26)27)6-7-16(15)29-19(21-17)23-10-8-22(9-11-23)18(28)20-13-4-2-1-3-5-13/h1-7,12H,8-11H2,(H,20,28) UTLILQNOKQDLCD-UHFFFAOYSA-N 50608669 CHEMBL3884935 DNA gyrase subunit B 510 ChEMBL 10.7270/Q2JD521W 32460040 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608669&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 134131596 494498417 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51512157 [O-][N+](=O)c1ccc2sc(nc(=O)c2c1)N1CCN(CC1)C(=S)Nc1ccc(Cl)cc1 InChI=1S/C19H16ClN5O3S2/c20-12-1-3-13(4-2-12)21-18(29)23-7-9-24(10-8-23)19-22-17(26)15-11-14(25(27)28)5-6-16(15)30-19/h1-6,11H,7-10H2,(H,21,29) VFMXIECOROEWQN-UHFFFAOYSA-N 50608670 CHEMBL3883797 DNA gyrase subunit B 820 ChEMBL 10.7270/Q2JD521W 32460040 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608670&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 134129998 494498418 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897 51512158 Cc1ccc(NC(=S)N2CCN(CC2)c2nc(=O)c3cc(ccc3s2)[N+]([O-])=O)cc1 InChI=1S/C20H19N5O3S2/c1-13-2-4-14(5-3-13)21-19(29)23-8-10-24(11-9-23)20-22-18(26)16-12-15(25(27)28)6-7-17(16)30-20/h2-7,12H,8-11H2,1H3,(H,21,29) OZIGHEHIXXYXHF-UHFFFAOYSA-N 50608671 CHEMBL3883383 DNA gyrase subunit B 770 ChEMBL 10.7270/Q2JD521W 32460040 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007840&target=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608671&enzyme=DNA+gyrase+subunit+B&column=ki&startPg=0&Increment=50&submit=Search 134131268 494498419 1 MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQLHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQGAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEVVDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIVDFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDRKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQLTHWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPRKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQPPLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV 2ZJT,5BS8,5BTA,5BTC,5BTD,5BTF,5BTG,5BTI,5BTL,5BTN,7UGW DNA gyrase subunit B GYRB_MYCTU P9WG45 L0T585 P0C5C5 P41514 P77897