BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50880417 CCn1c2ccc(cc2c(=O)n(-c2ccccc2C)c1=O)C(=O)C1C(=O)CCCC1=O InChI=1S/C24H22N2O5/c1-3-25-18-12-11-15(22(29)21-19(27)9-6-10-20(21)28)13-16(18)23(30)26(24(25)31)17-8-5-4-7-14(17)2/h4-5,7-8,11-13,21H,3,6,9-10H2,1-2H3 QTNUUZSOJHCTAI-UHFFFAOYSA-N 50264305 CHEMBL4102251 4-hydroxyphenylpyruvate dioxygenase 5.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264305&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137661969 404341800 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880421 COc1nc2c(C)cccc2cc1C(=O)C1C(=O)CCCC1=O InChI=1S/C18H17NO4/c1-10-5-3-6-11-9-12(18(23-2)19-16(10)11)17(22)15-13(20)7-4-8-14(15)21/h3,5-6,9,15H,4,7-8H2,1-2H3 VHMZGSGJYNNMBE-UHFFFAOYSA-N 50264306 CHEMBL4071950 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264306&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137638131 404341801 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880423 Cc1cccc2cc(C(=O)C3C(=O)CCCC3=O)c(nc12)C#N InChI=1S/C18H14N2O3/c1-10-4-2-5-11-8-12(13(9-19)20-17(10)11)18(23)16-14(21)6-3-7-15(16)22/h2,4-5,8,16H,3,6-7H2,1H3 YMXIEUOTJWJQSP-UHFFFAOYSA-N 50264307 CHEMBL4093474 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264307&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137653031 404341802 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880427 CC1CC(=O)C(C(=O)c2cc3cccc(C)c3nc2C)C(=O)C1 InChI=1S/C19H19NO3/c1-10-7-15(21)17(16(22)8-10)19(23)14-9-13-6-4-5-11(2)18(13)20-12(14)3/h4-6,9-10,17H,7-8H2,1-3H3 WIYOMXWKRQOVIX-UHFFFAOYSA-N 50264308 CHEMBL4061385 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264308&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137636831 404341803 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880431 CC1CC(=O)C(C(=O)c2cc3cccc(C)c3nc2C#N)C(=O)C1 InChI=1S/C19H16N2O3/c1-10-6-15(22)17(16(23)7-10)19(24)13-8-12-5-3-4-11(2)18(12)21-14(13)9-20/h3-5,8,10,17H,6-7H2,1-2H3 NUFMFXZEOVVTOR-UHFFFAOYSA-N 50264309 CHEMBL4060588 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264309&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137636800 404341804 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880435 Cc1ccccc1OCC(=O)C1C(=O)CCCC1=O InChI=1S/C15H16O4/c1-10-5-2-3-8-14(10)19-9-13(18)15-11(16)6-4-7-12(15)17/h2-3,5,8,15H,4,6-7,9H2,1H3 VHSJINLBASWFDK-UHFFFAOYSA-N 50264333 CHEMBL4082475 4-hydroxyphenylpyruvate dioxygenase 31 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264333&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137647201 404341805 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880558 Clc1ccccc1OCC(=O)C1C(=O)CCCC1=O InChI=1S/C14H13ClO4/c15-9-4-1-2-7-13(9)19-8-12(18)14-10(16)5-3-6-11(14)17/h1-2,4,7,14H,3,5-6,8H2 IHQQGFRMWADCQW-UHFFFAOYSA-N 50264334 CHEMBL4090319 4-hydroxyphenylpyruvate dioxygenase 31 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264334&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137643996 404341806 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880569 [O-][N+](=O)c1ccc(OCC(=O)C2C(=O)CCCC2=O)cc1 InChI=1S/C14H13NO6/c16-11-2-1-3-12(17)14(11)13(18)8-21-10-6-4-9(5-7-10)15(19)20/h4-7,14H,1-3,8H2 UVOKSLBOOBBFFE-UHFFFAOYSA-N 50264335 CHEMBL4080003 4-hydroxyphenylpyruvate dioxygenase 31 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264335&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137652439 404341807 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880570 CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 IUQAXCIUEPFPSF-UHFFFAOYSA-N 50264336 TEMBOTRIONE 4-hydroxyphenylpyruvate dioxygenase 13 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264336&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 11556911 404341808 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880571 CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)[C@@]2(C)C1=O InChI=1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,11,22-23H,1-4H3/t11?,18-/m0/s1 CUCUKLJLRRAKFN-MCEAHNFKSA-N 50056923 (+)-usnic acid::(9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyldibenzo[b,d]furan-1(9bH)-one::(R)-usnic acid::CHEMBL367881::d-Usnic acid::d-Usninic acid 4-hydroxyphenylpyruvate dioxygenase 70 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056923&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 461310 103953053 38320 CHEMBL367881 C05153 ZINC53007738 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880572 Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccccc1 InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 26667 (2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one::(S)-5,7-dihydroxyflavanone::CHEMBL399910 4-hydroxyphenylpyruvate dioxygenase 73000 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26667&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search KML 8A0R,7YJ8,7YJA 68071 57298379 28157 CHEMBL399910 C09827 ZINC00073693 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880574 CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1 InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 PQTBTIFWAXVEPB-UHFFFAOYSA-N 50075318 2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-cyclohex-2-enone::CHEMBL73467 4-hydroxyphenylpyruvate dioxygenase 250 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075318&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 5BQ 6ISD 91760 103968461 CHEMBL73467 ZINC02382749 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880575 CC1(C)C(=O)C(C(=O)CCc2ccccc2)C(=O)C(C)(C)C1=O InChI=1S/C19H22O4/c1-18(2)15(21)14(16(22)19(3,4)17(18)23)13(20)11-10-12-8-6-5-7-9-12/h5-9,14H,10-11H2,1-4H3 HDCYLHJYUHYIQL-UHFFFAOYSA-N 50264338 CHEMBL4062499 4-hydroxyphenylpyruvate dioxygenase 750 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264338&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 70584010 404341810 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880576 CCCCCCCCCC(=O)C1C(=O)C(C)(C)C(=O)C(C)(C)C1=O InChI=1S/C20H32O4/c1-6-7-8-9-10-11-12-13-14(21)15-16(22)19(2,3)18(24)20(4,5)17(15)23/h15H,6-13H2,1-5H3 UKYHLLGYGAUXBA-UHFFFAOYSA-N 50264344 CHEMBL4082652 4-hydroxyphenylpyruvate dioxygenase 19 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264344&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 10308749 404341811 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880745 CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(c1)[N+]([O-])=O InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 KPUREKXXPHOJQT-UHFFFAOYSA-N 50264337 CHEBI:38321::MESOTRIONE 4-hydroxyphenylpyruvate dioxygenase 13 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264337&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 175967 404341809 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880746 CC(C)CC(=O)C1C(=O)C(C)(C)C(=O)C(C)(C)C1=O InChI=1S/C15H22O4/c1-8(2)7-9(16)10-11(17)14(3,4)13(19)15(5,6)12(10)18/h8,10H,7H2,1-6H3 YDWYMAHAWHBPPT-UHFFFAOYSA-N 50264348 CHEMBL4090482 4-hydroxyphenylpyruvate dioxygenase 11800 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264348&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 3083632 404341815 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880751 Cc1nc2c(C)cccc2cc1C(=O)C1C(=O)CCCC1=O InChI=1S/C18H17NO3/c1-10-5-3-6-12-9-13(11(2)19-17(10)12)18(22)16-14(20)7-4-8-15(16)21/h3,5-6,9,16H,4,7-8H2,1-2H3 BZCJNHYQDUZSJV-UHFFFAOYSA-N 50264350 CHEMBL4080249 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264350&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137647588 404341817 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880752 COc1nc2c(C)cccc2cc1C(=O)C1C(=O)CC(C)CC1=O InChI=1S/C19H19NO4/c1-10-7-14(21)16(15(22)8-10)18(23)13-9-12-6-4-5-11(2)17(12)20-19(13)24-3/h4-6,9-10,16H,7-8H2,1-3H3 JLTNLSLMDXHZOA-UHFFFAOYSA-N 50264374 CHEMBL4069617 4-hydroxyphenylpyruvate dioxygenase 7.0 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264374&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137639364 104112401 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 50880753 Clc1ccc(OCC(=O)C2C(=O)CCCC2=O)cc1 InChI=1S/C14H13ClO4/c15-9-4-6-10(7-5-9)19-8-13(18)14-11(16)2-1-3-12(14)17/h4-7,14H,1-3,8H2 PKRKZPOUAOGMDA-UHFFFAOYSA-N 50264377 CHEMBL4069274 4-hydroxyphenylpyruvate dioxygenase 31 ChEMBL 10.1021/acs.jmedchem.6b01395 10.7270/Q2FN18ND 28128559 Santucci, A; Bernardini, G; Braconi, D; Petricci, E; Manetti, F Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264377&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 137634046 404341818 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184384 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)[n+]([O-])c(C)n1O InChI=1S/C16H19ClN2O6S/c1-5-25-16-12(26(23,24)6-2)8-7-11(13(16)17)15(20)14-9(3)18(21)10(4)19(14)22/h7-8,22H,5-6H2,1-4H3 GGWVCNFBTHDSCO-UHFFFAOYSA-N 50487117 CHEMBL2251444 4-hydroxyphenylpyruvate dioxygenase 190 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487117&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76315435 433954382 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184385 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)ncn1O InChI=1S/C15H17ClN2O5S/c1-4-23-15-11(24(21,22)5-2)7-6-10(12(15)16)14(19)13-9(3)17-8-18(13)20/h6-8,20H,4-5H2,1-3H3 ZZGALUOTCAIANV-UHFFFAOYSA-N 50487118 CHEMBL2251436 4-hydroxyphenylpyruvate dioxygenase 20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487118&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76308247 433954383 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184386 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(C(C)C)n1O InChI=1S/C18H23ClN2O5S/c1-6-26-17-13(27(24,25)7-2)9-8-12(14(17)19)16(22)15-11(5)20-18(10(3)4)21(15)23/h8-10,23H,6-7H2,1-5H3 DLEGFAAXKJKAHQ-UHFFFAOYSA-N 50487119 CHEMBL2251439 4-hydroxyphenylpyruvate dioxygenase 43 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487119&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76319115 433954384 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184387 Cc1nc(C)n(O)c1C(=O)c1ccc(c(C2=NOCC2)c1Cl)S(C)(=O)=O InChI=1S/C16H16ClN3O5S/c1-8-15(20(22)9(2)18-8)16(21)10-4-5-12(26(3,23)24)13(14(10)17)11-6-7-25-19-11/h4-5,22H,6-7H2,1-3H3 RREAPSPUYYEKRP-UHFFFAOYSA-N 50487120 CHEMBL2251430 4-hydroxyphenylpyruvate dioxygenase 36 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487120&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76308246 433954385 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184388 CSc1ccc(C(=O)c2c(C)nc(C)n2O)c(C)c1Cl InChI=1S/C14H15ClN2O2S/c1-7-10(5-6-11(20-4)12(7)15)14(18)13-8(2)16-9(3)17(13)19/h5-6,19H,1-4H3 MJAKASLCLLMWAI-UHFFFAOYSA-N 50487121 CHEMBL2251513 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487121&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76308248 433954386 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184389 COc1c(C)c(ccc1S(C)(=O)=O)C(=O)c1c(C)nc(C)n1O InChI=1S/C15H18N2O5S/c1-8-11(6-7-12(15(8)22-4)23(5,20)21)14(18)13-9(2)16-10(3)17(13)19/h6-7,19H,1-5H3 NINXKJKOATWEGR-UHFFFAOYSA-N 50487122 CHEMBL2251512 4-hydroxyphenylpyruvate dioxygenase 18000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487122&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76311891 433954387 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184390 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(-c2ccccc2)n1O InChI=1S/C21H21ClN2O5S/c1-4-29-20-16(30(27,28)5-2)12-11-15(17(20)22)19(25)18-13(3)23-21(24(18)26)14-9-7-6-8-10-14/h6-12,26H,4-5H2,1-3H3 XKXSGXWHGFFNEH-UHFFFAOYSA-N 50487123 CHEMBL2251442 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487123&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76311889 433954388 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184391 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(-c2cccn2C)n1O InChI=1S/C20H22ClN3O5S/c1-5-29-19-15(30(27,28)6-2)10-9-13(16(19)21)18(25)17-12(3)22-20(24(17)26)14-8-7-11-23(14)4/h7-11,26H,5-6H2,1-4H3 XXJGRUKZHWSFJV-UHFFFAOYSA-N 50487124 CHEMBL2251441 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487124&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76322780 433954389 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184392 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(-c2cccs2)n1O InChI=1S/C19H19ClN2O5S2/c1-4-27-18-14(29(25,26)5-2)9-8-12(15(18)20)17(23)16-11(3)21-19(22(16)24)13-7-6-10-28-13/h6-10,24H,4-5H2,1-3H3 UDTITBJIFNFVSP-UHFFFAOYSA-N 50487125 CHEMBL2251440 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487125&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76333594 433954390 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184393 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(C)n1O InChI=1S/C16H19ClN2O5S/c1-5-24-16-12(25(22,23)6-2)8-7-11(13(16)17)15(20)14-9(3)18-10(4)19(14)21/h7-8,21H,5-6H2,1-4H3 XFCAUTXVEDWYSG-UHFFFAOYSA-N 50487126 CHEMBL2251437 4-hydroxyphenylpyruvate dioxygenase 48 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487126&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76315434 433954391 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184394 CC(=O)C(=N\O)\C(=O)c1ccc(c(C2=NOCC2)c1Cl)S(C)(=O)=O InChI=1S/C14H13ClN2O6S/c1-7(18)13(16-20)14(19)8-3-4-10(24(2,21)22)11(12(8)15)9-5-6-23-17-9/h3-4,20H,5-6H2,1-2H3/b16-13- ZSHLTUKTPFXWFJ-SSZFMOIBSA-N 50487127 CHEMBL2251435 4-hydroxyphenylpyruvate dioxygenase 13000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487127&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 136245168 433954392 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184395 COc1c(C)c(ccc1S(C)(=O)=O)C(=O)C(=N/O)\C(C)=O InChI=1S/C13H15NO6S/c1-7-9(12(16)11(14-17)8(2)15)5-6-10(13(7)20-3)21(4,18)19/h5-6,17H,1-4H3/b14-11- VGBNJTGJLBZCRJ-KAMYIIQDSA-N 50487128 CHEMBL2251433 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487128&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 136241510 433954393 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184396 Cc1[nH]n(C)c(=O)c1C(=O)c1ccc(c(C2=NOCC2)c1Cl)S(C)(=O)=O InChI=1S/C16H16ClN3O5S/c1-8-12(16(22)20(2)18-8)15(21)9-4-5-11(26(3,23)24)13(14(9)17)10-6-7-25-19-10/h4-5,18H,6-7H2,1-3H3 QZCKRQFSHNNDPY-UHFFFAOYSA-N 50487129 CHEMBL3145394 4-hydroxyphenylpyruvate dioxygenase 190 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487129&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 21111945 433954394 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184397 Cc1nc(C)n(O)c1C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C13H13ClN2O4S/c1-7-12(16(18)8(2)15-7)13(17)10-5-4-9(6-11(10)14)21(3,19)20/h4-6,18H,1-3H3 DCDHYJOTXOZCJU-UHFFFAOYSA-N 50487130 CHEMBL2251514 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487130&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76319116 433954395 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184398 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(-c2ccc(Cl)cc2Cl)n1O InChI=1S/C21H19Cl3N2O5S/c1-4-31-20-16(32(29,30)5-2)9-8-14(17(20)24)19(27)18-11(3)25-21(26(18)28)13-7-6-12(22)10-15(13)23/h6-10,28H,4-5H2,1-3H3 MLVYFPIJOJSTIZ-UHFFFAOYSA-N 50487131 CHEMBL2251443 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487131&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76311890 433954396 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184399 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)c1c(C)nc(CC)n1O InChI=1S/C17H21ClN2O5S/c1-5-13-19-10(4)15(20(13)22)16(21)11-8-9-12(26(23,24)7-3)17(14(11)18)25-6-2/h8-9,22H,5-7H2,1-4H3 GLQQTLBLHKITKS-UHFFFAOYSA-N 50487132 CHEMBL2251438 4-hydroxyphenylpyruvate dioxygenase 71 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487132&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76319114 433954397 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184400 CSc1ccc(C(=O)C(=N/O)\C(C)=O)c(C)c1Cl InChI=1S/C12H12ClNO3S/c1-6-8(4-5-9(18-3)10(6)13)12(16)11(14-17)7(2)15/h4-5,17H,1-3H3/b14-11- KTIRZMPTCHXHEI-KAMYIIQDSA-N 50487133 CHEMBL2251434 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487133&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 136224076 433954398 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184401 Cc1nc(C)n(O)c1C(=O)c1c(C)cc(C)cc1C InChI=1S/C15H18N2O2/c1-8-6-9(2)13(10(3)7-8)15(18)14-11(4)16-12(5)17(14)19/h6-7,19H,1-5H3 HLFNTUJUCFSEMW-UHFFFAOYSA-N 50487134 CHEMBL2251516 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487134&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76315436 433954399 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184402 Cc1nc(C)n(O)c1C(=O)c1ccc(c2ncccc12)S(C)(=O)=O InChI=1S/C16H15N3O4S/c1-9-15(19(21)10(2)18-9)16(20)12-6-7-13(24(3,22)23)14-11(12)5-4-8-17-14/h4-8,21H,1-3H3 NRIZWWCLSCCNDD-UHFFFAOYSA-N 50487135 CHEMBL2251515 4-hydroxyphenylpyruvate dioxygenase >20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487135&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 76329952 433954400 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1 51184403 CCOc1c(Cl)c(ccc1S(=O)(=O)CC)C(=O)C(=N/O)\C(C)=O InChI=1S/C14H16ClNO6S/c1-4-22-14-10(23(20,21)5-2)7-6-9(11(14)15)13(18)12(16-19)8(3)17/h6-7,19H,4-5H2,1-3H3/b16-12- ZWSIDOGGGXAWLO-VBKFSLOCSA-N 50487136 CHEMBL2251432 4-hydroxyphenylpyruvate dioxygenase 20000 ChEMBL 10.1016/j.bmc.2008.11.006 10.7270/Q2CN76S1 19028100 Witschel, M BASF SE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007530&target=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487136&enzyme=4-hydroxyphenylpyruvate+dioxygenase&column=ki&startPg=0&Increment=50&submit=Search 136224075 433954401 1 MGHQNAAVSENQNHDDGAASSPGFKLVGFSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSLSAGEIKPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDASSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLASNDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 1SP9,1SQD,1TFZ,1TG5,5XGK,5YWG,5YWH,5YWI,5YWK,5YY6,5YY7,6ISD,6J63,6JX9,6LGT,6M6D,7CJK,7CQR,7CQS,7E0X,7V6X,7VC8,7VO8,7WJ8,7WJJ,7WJK,7X5R,7X5S,7X5U,7X5W,7X5X,7X5Y,7X5Z,7X62,7X64,7X65,7X67,7X69,7X6M,7X6N,7X8D,7X8H,7X8I,7XVH,8HOW 4-hydroxyphenylpyruvate dioxygenase HPPD_ARATH P93836 F4IDP1 O04330 Q9SHK1