BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51111212 NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c23)CC1 InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1 DHMTURDWPRKSOA-RUZDIDTESA-N 14459 (+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(R)-yl)-1-piperidin-yl]-2-oxo-ethyl]-1-piperidinecarboxamide::4-(2-{4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide::CHEMBL298734::Lonafarnib::SCH 66336::Sarasar Geranylgeranyl transferase type-1 subunit beta >1000 ChEMBL 10.1021/acs.jmedchem.6b01817 10.7270/Q2542R5N 28505447 Buuh, ZY; Lyu, Z; Wang, RE Temple University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=14459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=14459&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 336 1O5M 148195 46514799 CHEMBL298734 ZINC03950115 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173402 OC(=O)[C@H](Cc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1coc(n1)-c1ccccc1 InChI=1S/C46H40N6O6/c53-41(28-47-42(54)40-30-58-44(51-40)33-18-8-2-9-19-33)49-38(26-32-16-6-1-7-17-32)43(55)50-39(45(56)57)27-37-29-52(31-48-37)46(34-20-10-3-11-21-34,35-22-12-4-13-23-35)36-24-14-5-15-25-36/h1-25,29-31,38-39H,26-28H2,(H,47,54)(H,49,53)(H,50,55)(H,56,57)/t38-,39-/m0/s1 CASCIOQXOQWQCW-YDAXCOIMSA-N 50481906 CHEMBL1075839 Geranylgeranyl transferase type-1 subunit beta 3400 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481906&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 44605976 433949171 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173403 OC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](Cc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)c1coc(n1)-c1ccccc1 InChI=1S/C43H38N8O6/c52-38(48-36(42(55)56)21-33-23-44-27-46-33)24-45-39(53)35(49-40(54)37-26-57-41(50-37)29-13-5-1-6-14-29)22-34-25-51(28-47-34)43(30-15-7-2-8-16-30,31-17-9-3-10-18-31)32-19-11-4-12-20-32/h1-20,23,25-28,35-36H,21-22,24H2,(H,44,46)(H,45,53)(H,48,52)(H,49,54)(H,55,56)/t35-,36-/m0/s1 SZIZPKHQRQEYCR-ZPGRZCPFSA-N 50481907 CHEMBL1075810 Geranylgeranyl transferase type-1 subunit beta 14000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481907&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 44605803 433949172 C03095 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173404 CCCCCCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CN(C)CCc1ccccn1)Cc1ccc(O)cc1 InChI=1S/C40H53N7O4/c1-3-4-5-6-10-16-38(49)45-37(26-33-27-41-29-43-33)40(51)46-36(25-30-13-8-7-9-14-30)39(50)44-34(24-31-17-19-35(48)20-18-31)28-47(2)23-21-32-15-11-12-22-42-32/h7-9,11-15,17-20,22,27,29,34,36-37,48H,3-6,10,16,21,23-26,28H2,1-2H3,(H,41,43)(H,44,50)(H,45,49)(H,46,51)/t34-,36-,37-/m0/s1 DVGMHJCTTBZAAP-RHNUXINZSA-N 50481908 CHEMBL1075861 Geranylgeranyl transferase type-1 subunit beta 98000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481908&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 46878954 433949173 C00615 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173405 CCCCCCCCCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N(C)CCc1ccccn1 InChI=1S/C40H55N9O5/c1-3-4-5-6-7-8-9-10-14-37(51)46-34(23-31-25-41-27-44-31)38(52)47-35(24-32-26-42-28-45-32)39(53)48-36(22-29-15-17-33(50)18-16-29)40(54)49(2)21-19-30-13-11-12-20-43-30/h11-13,15-18,20,25-28,34-36,50H,3-10,14,19,21-24H2,1-2H3,(H,41,44)(H,42,45)(H,46,51)(H,47,52)(H,48,53)/t34-,35-,36-/m0/s1 XTWPUBVVNIJMOQ-KVBYWJEESA-N 50481909 CHEMBL1075863 Geranylgeranyl transferase type-1 subunit beta 35000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481909&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search BD9 3HXF 24879235 433949174 C00615 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173406 CCCCCCCCCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N(C)CCc1ccccn1 InChI=1S/C43H57N7O5/c1-3-4-5-6-7-8-9-13-19-40(52)47-38(29-35-30-44-31-46-35)42(54)48-37(27-32-16-11-10-12-17-32)41(53)49-39(28-33-20-22-36(51)23-21-33)43(55)50(2)26-24-34-18-14-15-25-45-34/h10-12,14-18,20-23,25,30-31,37-39,51H,3-9,13,19,24,26-29H2,1-2H3,(H,44,46)(H,47,52)(H,48,54)(H,49,53)/t37-,38-,39-/m0/s1 KGRSUMUKTYCXCP-IGMOWHQGSA-N 50481910 CHEMBL1075859 Geranylgeranyl transferase type-1 subunit beta >100000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481910&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search BD8 3HXE 24879234 433949175 C00615 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173407 OC(=O)[C@H](Cc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)c1coc(n1)-c1ccccc1 InChI=1S/C43H38N8O6/c52-38(24-45-39(53)35(21-33-23-44-27-46-33)49-40(54)37-26-57-41(50-37)29-13-5-1-6-14-29)48-36(42(55)56)22-34-25-51(28-47-34)43(30-15-7-2-8-16-30,31-17-9-3-10-18-31)32-19-11-4-12-20-32/h1-20,23,25-28,35-36H,21-22,24H2,(H,44,46)(H,45,53)(H,48,52)(H,49,54)(H,55,56)/t35-,36-/m0/s1 FEZUJRMBAHUDQP-ZPGRZCPFSA-N 50481911 CHEMBL1075809 Geranylgeranyl transferase type-1 subunit beta 13000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481911&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 44605626 433949176 C00615 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51173408 CCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N(C)CCc1ccccn1 InChI=1S/C43H57N7O6/c1-3-4-5-6-7-8-9-10-14-40(53)47-37(26-31-15-19-35(51)20-16-31)41(54)48-38(28-34-29-44-30-46-34)42(55)49-39(27-32-17-21-36(52)22-18-32)43(56)50(2)25-23-33-13-11-12-24-45-33/h11-13,15-22,24,29-30,37-39,51-52H,3-10,14,23,25-28H2,1-2H3,(H,44,46)(H,47,53)(H,48,54)(H,49,55)/t37-,38-,39-/m0/s1 BEOJGBMJLYVUHG-IGMOWHQGSA-N 50481912 CHEMBL1075865 Geranylgeranyl transferase type-1 subunit beta >100000 ChEMBL 10.1021/jm901117d 10.7270/Q25X2CS3 19894725 Tan, KT; Guiu-Rozas, E; Bon, RS; Guo, Z; Delon, C; Wetzel, S; Arndt, S; Alexandrov, K; Waldmann, H; Goody, RS; Wu, YW; Blankenfeldt, W Max Planck Institute of Molecular Physiology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50481912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50481912&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 24879172 433949177 C00615 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51229992 OP(O)(=O)C(Cn1cnc2cc(F)c(F)cc12)P(O)(O)=O InChI=1S/C9H10F2N2O6P2/c10-5-1-7-8(2-6(5)11)13(4-12-7)3-9(20(14,15)16)21(17,18)19/h1-2,4,9H,3H2,(H2,14,15,16)(H2,17,18,19) TUOARNRROAEGKV-UHFFFAOYSA-N 50504717 CHEMBL4459281 Geranylgeranyl transferase type-1 subunit beta 122000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504717&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155526409 440713302 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51229993 Cc1cc2ncn(CC(C(O)=O)P(O)(O)=O)c2cc1C InChI=1S/C12H15N2O5P/c1-7-3-9-10(4-8(7)2)14(6-13-9)5-11(12(15)16)20(17,18)19/h3-4,6,11H,5H2,1-2H3,(H,15,16)(H2,17,18,19) KLWGAEZHEYXBGT-UHFFFAOYSA-N 50504714 CHEMBL4460301 Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504714&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155528021 440713299 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51229994 OC(=O)C(Cn1cnc2cc(F)c(F)cc12)P(O)(O)=O InChI=1S/C10H9F2N2O5P/c11-5-1-7-8(2-6(5)12)14(4-13-7)3-9(10(15)16)20(17,18)19/h1-2,4,9H,3H2,(H,15,16)(H2,17,18,19) XWMOZTADYNUFHE-UHFFFAOYSA-N 50504718 CHEMBL4564870 Geranylgeranyl transferase type-1 subunit beta 145000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504718&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155560088 440713303 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51230005 CC(Cn1cnc2ccccc12)(C(O)=O)P(O)(O)=O InChI=1S/C11H13N2O5P/c1-11(10(14)15,19(16,17)18)6-13-7-12-8-4-2-3-5-9(8)13/h2-5,7H,6H2,1H3,(H,14,15)(H2,16,17,18) QUDUQQDLBUPHAQ-UHFFFAOYSA-N 50504715 CHEMBL4514446 Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504715&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155539327 440713300 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51230008 Cc1cc2ncn(CC(P(O)(O)=O)P(O)(O)=O)c2cc1C InChI=1S/C11H16N2O6P2/c1-7-3-9-10(4-8(7)2)13(6-12-9)5-11(20(14,15)16)21(17,18)19/h3-4,6,11H,5H2,1-2H3,(H2,14,15,16)(H2,17,18,19) LHHSPWONSLWNQK-UHFFFAOYSA-N 50504720 CHEMBL4529809 Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504720&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155545691 440713305 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51230009 OC(=O)C(Cn1cnc2ccccc12)P(O)(O)=O InChI=1S/C10H11N2O5P/c13-10(14)9(18(15,16)17)5-12-6-11-7-3-1-2-4-8(7)12/h1-4,6,9H,5H2,(H,13,14)(H2,15,16,17) LQZXULNZTSCOBJ-UHFFFAOYSA-N 50504719 CHEMBL4438314 Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504719&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155512943 440713304 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51230011 OP(O)(=O)C(Cn1cnc2ccccc12)P(O)(O)=O InChI=1S/C9H12N2O6P2/c12-18(13,14)9(19(15,16)17)5-11-6-10-7-3-1-2-4-8(7)11/h1-4,6,9H,5H2,(H2,12,13,14)(H2,15,16,17) ISSICOMKRRPVPD-UHFFFAOYSA-N 50273716 CHEMBL457423::[2-(Benzoimidazol-1-yl)ethyl]-bisphosphonic acid Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273716&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 5277505 104117728 CHEMBL457423 ZINC33818248 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610 51230015 CC(Cn1cnc2ccccc12)(P(O)(O)=O)P(O)(O)=O InChI=1S/C10H14N2O6P2/c1-10(19(13,14)15,20(16,17)18)6-12-7-11-8-4-2-3-5-9(8)12/h2-5,7H,6H2,1H3,(H2,13,14,15)(H2,16,17,18) MRVZYYYNUNGBNW-UHFFFAOYSA-N 50504716 CHEMBL4589567 Geranylgeranyl transferase type-1 subunit beta >1000000 ChEMBL 10.1016/j.bmcl.2019.126757 10.7270/Q2JM2DW5 31699606 Bhuiyan, NH; Varney, ML; Wiemer, DF; Holstein, SA University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50504716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50007258&target=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50504716&enzyme=Geranylgeranyl+transferase+type-1+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 155568571 440713301 1 MAATEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHISS 1N4P,1N4Q,1N4R,1N4S,1S64,1TNB,1TNO,1TNU,1TNY,1TNZ Geranylgeranyl transferase type-1 subunit beta PGTB1_RAT P53610