BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 455105 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 Proteasome subunit alpha type-6 14800 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455106 CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3 XSCGXQMFQXDFCW-UHFFFAOYSA-N 67544 N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanamine;hydrochloride::N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine;hydrochloride::SR-01000000224-4::TRIFLUPROMAZINE::cid_66069::dimethyl-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]amine;hydrochloride::med.21724, Compound Triflupromazine Proteasome subunit alpha type-6 7800 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67544&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 5568 252645839 DB00508 ZINC00538507 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455107 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine Proteasome subunit alpha type-6 12000 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455108 CN1CCCC(CC2c3ccccc3Sc3ccccc23)C1 InChI=1S/C20H23NS/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20/h2-5,8-11,15,18H,6-7,12-14H2,1H3 MJFJKKXQDNNUJF-UHFFFAOYSA-N 79211 1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine;hydrate;hydrochloride::METHIXENE::MLS002153842::Metixene::Metixene hydrochloride::SMR001233205::cid_71177 Proteasome subunit alpha type-6 11900 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79211&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 4167 252655906 DB00340 ZINC01713960 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455109 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 GDLIGKIOYRNHDA-UHFFFAOYSA-N 77970 3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine Proteasome subunit alpha type-6 12400 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77970&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search CXX 4MMA,2QEI,6G9I,2Q6H 2801 252654733 3755 DB01242 C06918 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455110 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 Proteasome subunit alpha type-6 9900 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455111 CC(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H20ClNS/c1-13(2)6-5-11-20-15-7-3-4-8-17(15)21-18-10-9-14(19)12-16(18)20/h3-4,7-10,12-13H,5-6,11H2,1-2H3 IMYKKTVSQLRQPB-UHFFFAOYSA-N 65507 CPZ analog, 1 Proteasome subunit alpha type-6 >25000 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65507&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953890 350083128 ZINC15953031 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455112 OS(=O)(=O)CCCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C16H16ClNO3S2/c17-12-7-8-16-14(11-12)18(9-3-4-10-23(19,20)21)13-5-1-2-6-15(13)22-16/h1-2,5-8,11H,3-4,9-10H2,(H,19,20,21) LYNDVTVYYWZTSM-UHFFFAOYSA-N 65508 CPZ analog, 2 Proteasome subunit alpha type-6 6300 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65508&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 22572547 350083129 C15521 ZINC60238933 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455113 OS(=O)(=O)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C15H14ClNO3S2/c16-11-6-7-15-13(10-11)17(8-3-9-22(18,19)20)12-4-1-2-5-14(12)21-15/h1-2,4-7,10H,3,8-9H2,(H,18,19,20) WOZZYXWXMZHYCA-UHFFFAOYSA-N 65509 CPZ analog, 3 Proteasome subunit alpha type-6 >25000 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65509&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 54442341 350083130 C15521 ZINC05185218 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455114 OS(=O)(=O)CCCCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H18ClNO3S2/c18-13-8-9-17-15(12-13)19(10-4-1-5-11-24(20,21)22)14-6-2-3-7-16(14)23-17/h2-3,6-9,12H,1,4-5,10-11H2,(H,20,21,22) FKUGMGRFWHLRJB-UHFFFAOYSA-N 65510 CPZ analog, 4 Proteasome subunit alpha type-6 >25000 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65510&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953891 350083131 C15521 ZINC02623180 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455115 Clc1ccc2Sc3ccccc3N(CCCCN3CCOCC3)c2c1 InChI=1S/C20H23ClN2OS/c21-16-7-8-20-18(15-16)23(17-5-1-2-6-19(17)25-20)10-4-3-9-22-11-13-24-14-12-22/h1-2,5-8,15H,3-4,9-14H2 NYTLEHCHADNPCL-UHFFFAOYSA-N 65511 CPZ analog, 5 Proteasome subunit alpha type-6 8900 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65511&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953892 350083132 ZINC04056380 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455116 OC(=O)C#CCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C16H10ClNO2S/c17-11-7-8-15-13(10-11)18(9-3-6-16(19)20)12-4-1-2-5-14(12)21-15/h1-2,4-5,7-8,10H,9H2,(H,19,20) RUZNPXQEIDOOFE-UHFFFAOYSA-N 65512 CPZ analog, 6 Proteasome subunit alpha type-6 >25000 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65512&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953893 350083133 ZINC04034780 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455117 OC(=O)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc23)cc1 InChI=1S/C20H14ClNO2S/c21-15-9-10-19-17(11-15)22(16-3-1-2-4-18(16)25-19)12-13-5-7-14(8-6-13)20(23)24/h1-11H,12H2,(H,23,24) YKOKIGJUJYYSAF-UHFFFAOYSA-N 65513 CPZ analog, 7 Proteasome subunit alpha type-6 6400 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65513&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953894 350083134 ZINC03031577 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 455118 COC(=O)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc23)cc1 InChI=1S/C21H16ClNO2S/c1-25-21(24)15-8-6-14(7-9-15)13-23-17-4-2-3-5-19(17)26-20-11-10-16(22)12-18(20)23/h2-12H,13H2,1H3 HIDDWKTVRSKQSL-UHFFFAOYSA-N 65514 CPZ analog, 8 Proteasome subunit alpha type-6 15600 7.5 37.00 C Curated from the literature by BindingDB 10.1021/acschembio.7b00489 10.7270/Q2DV1H2F 28719185 aid1794859 Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Michigan State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65514&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 131953895 350083135 ZINC03369390 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237300 COC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B(O)O InChI=1S/C16H23BCl2N2O5/c1-9(2)6-14(17(24)25)21-16(23)13(8-26-3)20-15(22)11-7-10(18)4-5-12(11)19/h4-5,7,9,13-14,24-25H,6,8H2,1-3H3,(H,20,22)(H,21,23)/t13-,14-/m0/s1 QZRBBSWQICQORE-KBPBESRZSA-N 50462625 CHEMBL4243375::US11542283, Compound IV-8 Proteasome subunit alpha type-6 7.52 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462625&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 145983051 433929890 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237301 CSC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B(O)O InChI=1S/C16H23BCl2N2O4S/c1-9(2)6-14(17(24)25)21-16(23)13(8-26-3)20-15(22)11-7-10(18)4-5-12(11)19/h4-5,7,9,13-14,24-25H,6,8H2,1-3H3,(H,20,22)(H,21,23)/t13-,14-/m0/s1 QFAAHRPOEKMFBC-KBPBESRZSA-N 588478 (R)-N-(2,5-dichlorobenzoyl)-3- methylmercaptopropionamido-D-leucine boric acid::US11542283, Compound IV-9 Proteasome subunit alpha type-6 4.86 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=588478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=588478&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237302 COC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B1OCCNCCO1 InChI=1S/C20H30BCl2N3O5/c1-13(2)10-18(21-30-8-6-24-7-9-31-21)26-20(28)17(12-29-3)25-19(27)15-11-14(22)4-5-16(15)23/h4-5,11,13,17-18,24H,6-10,12H2,1-3H3,(H,25,27)(H,26,28)/t17-,18-/m0/s1 SOGYIICGUUSWIE-ROUUACIJSA-N 50462603 CHEMBL4248209::US11542283, Compound V-8A Proteasome subunit alpha type-6 7.02 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462603&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 145984824 433929868 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237303 COC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O InChI=1S/C22H27BCl2N2O10/c1-11(2)6-16(23-36-18(30)9-22(37-23,21(33)34)8-17(28)29)27-20(32)15(10-35-3)26-19(31)13-7-12(24)4-5-14(13)25/h4-5,7,11,15-16H,6,8-10H2,1-3H3,(H,26,31)(H,27,32)(H,28,29)(H,33,34)/t15-,16-,22?/m0/s1 PHSUUCWSSNPOAB-SOOSJGDTSA-N 588480 (S)-N-(2,5-dichlorobenzoyl)-3- methoxypropionamido-D-leucine borate citrate::US11542283, Compound V-8B Proteasome subunit alpha type-6 8.20 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=588480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=588480&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237304 CSC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B1OCCNCCO1 InChI=1S/C20H30BCl2N3O4S/c1-13(2)10-18(21-29-8-6-24-7-9-30-21)26-20(28)17(12-31-3)25-19(27)15-11-14(22)4-5-16(15)23/h4-5,11,13,17-18,24H,6-10,12H2,1-3H3,(H,25,27)(H,26,28)/t17-,18-/m0/s1 GNNMNVFGCQSIQV-ROUUACIJSA-N 50516758 CHEMBL4444471::US11542283, Compound V-9A Proteasome subunit alpha type-6 5.69 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516758&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 147672609 440725340 C03800 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237305 CSC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O InChI=1S/C22H27BCl2N2O9S/c1-11(2)6-16(23-35-18(30)9-22(36-23,21(33)34)8-17(28)29)27-20(32)15(10-37-3)26-19(31)13-7-12(24)4-5-14(13)25/h4-5,7,11,15-16H,6,8-10H2,1-3H3,(H,26,31)(H,27,32)(H,28,29)(H,33,34)/t15-,16-,22?/m0/s1 XMDHSNUQXDKNDC-SOOSJGDTSA-N 588482 (R)-N-(2,5-dichlorobenzoyl)-3- methylmercaptopropionamido-D- leucine borate citratte::US11542283, Compound V-9B Proteasome subunit alpha type-6 6.60 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=588482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=588482&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237306 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1 GXJABQQUPOEUTA-RDJZCZTQSA-N 50069989 (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid::(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-6-carboxamido)propanamido)butylboronic acid::BORTEZOMIB::CHEMBL325041::Dipeptidyl boronic acid derivative::LDP-341::N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE::PS-341::Peptidyl boronic acid derivative::US11542283, Compound Velcade::Velcade::cid_387447 Proteasome subunit alpha type-6 9.92 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069989&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search BO2 4QVY,4QVN,4QVM,4QVL,3MG0,5L66,4QWU,4QW0,4QW1,4QW3,6TD5,2F16,5D0X,4QVW,4QVV,4QVQ,4QVP,5L5F,5L5Z,7KRZ,6HWM,6HWD,7LXT,6X27,4YPM,5BXN,5LF3,7Q0Y,8DVH,5CZ7,4FWD 387447 103963945 52717 CHEMBL325041 DB00188 6391 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60 1237307 CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O InChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-17(29)8-20(34-21,19(31)32)7-16(27)28)25-15(26)9-24-18(30)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,30)(H,25,26)(H,27,28)(H,31,32)/t14-,20?/m0/s1 YTXSYWAKVMZICI-PVCZSOGJSA-N 50462621 CHEMBL1813256::MLN-9708::US11542283, Compound MLN-9708 Proteasome subunit alpha type-6 7.47 US Patent 10.7270/Q27P937G US11542283 Qin, Y JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006561&target=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462621&enzyme=Proteasome+subunit+alpha+type-6&column=ki&startPg=0&Increment=50&submit=Search 49867936 433929886 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 1IRU,4R3O,4R67,5A0Q,5GJQ,5GJR,5L4G,5LE5,5LEX,5LEY,5LEZ,5LF0,5LF1,5LF3,5LF4,5LF6,5LF7,5LN3,5M32,5T0G,5T0H,5T0I,5T0J,5VFO,5VFP,5VFQ,5VFR,5VFS,5VFT,5VFU,6AVO,6E5B,6EPC,6EPD,6EPE,6EPF,6KWY,6MSB,6MSD,6MSE,6MSG,6MSH,6MSJ,6MSK,6R70,6REY,6RGQ,6TU3,6WJD,6WJN,6XMJ,7AWE,7B12,7DR6,7DR7,7DRW,7LXV,7NAN,7NAO,7NAP,7NAQ,7NHT,7PG9,7QXN,7QXP,7QXU,7QXW,7QXX,7QY7,7QYA,7QYB,7V5G,7V5M,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M,8CVR,8CVS,8CVT,8CXB,8FZ5,8FZ6 Proteasome subunit alpha type-6 PSA6_HUMAN P60900 B2R7J9 B4DQR4 B4DXJ9 P34062 Q6IB60