BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
50309154	Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1	InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3	JUWDSDKJBMFLHE-UHFFFAOYSA-N	50437694	CHEMBL1410015	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 4000							ChEMBL	10.1021/jm501061a	10.7270/Q29025GH	25364867			Ndubaku, C; Tsui, V	Genentech	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	IU1	6IIK	675434	175450011		CHEMBL1410015				ZINC00038235	1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51071185	Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1	InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3	JUWDSDKJBMFLHE-UHFFFAOYSA-N	50437694	CHEMBL1410015	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 4000							ChEMBL	10.1016/j.bmcl.2013.05.093	10.7270/Q2T15528	23791076			Okada, K; Ye, YQ; Taniguchi, K; Yoshida, A; Akiyama, T; Yoshioka, Y; Onose, J; Koshino, H; Takahashi, S; Yajima, A; Abe, N; Yajima, S	Tokyo University of Agriculture	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	IU1	6IIK	675434	175450011		CHEMBL1410015				ZINC00038235	1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51257979	Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1	InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3	JUWDSDKJBMFLHE-UHFFFAOYSA-N	50437694	CHEMBL1410015	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 12300							ChEMBL	10.1021/acs.jmedchem.9b01138	10.7270/Q2GF0XTC	31682427			Schauer, NJ; Magin, RS; Liu, X; Doherty, LM; Buhrlage, SJ	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	IU1	6IIK	675434	175450011		CHEMBL1410015				ZINC00038235	1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51330801	C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12	InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1	LSPPODQSTNTKTE-AAORLSLPSA-N	50538571	CHEMBL4635160	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.0c00245	10.7270/Q2XK8K2T	32302140			Leger, PR; Hu, DX; Biannic, B; Bui, M; Han, X; Karbarz, E; Maung, J; Okano, A; Osipov, M; Shibuya, GM; Young, K; Higgs, C; Abraham, B; Bradford, D; Cho, C; Colas, C; Jacobson, S; Ohol, YM; Pookot, D; Rana, P; Sanchez, J; Shah, N; Sun, M; Wong, S; Brockstedt, DG; Kassner, PD; Schwarz, JB; Wustrow, DJ	RAPT Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50538571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50538571&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			138609936	442140134							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387461	CC(=O)Nc1nc2ccccn2c1-c1ccc(O)cc1	InChI=1S/C15H13N3O2/c1-10(19)16-15-14(11-5-7-12(20)8-6-11)18-9-3-2-4-13(18)17-15/h2-9,20H,1H3,(H,16,19)	WTGODXTULSTYNY-UHFFFAOYSA-N	50560581	CHEMBL4792948	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560581&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162671367	461830973							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387462	Nc1nc2ccccn2c1-c1ccc(O)cc1	InChI=1S/C13H11N3O/c14-13-12(9-4-6-10(17)7-5-9)16-8-2-1-3-11(16)15-13/h1-8,17H,14H2	YAVLEYZGIQRBDK-UHFFFAOYSA-N	50560582	CHEMBL4746931	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560582&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162649303	461830974							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387463	CN(C)c1nc2ccccn2c1-c1ccc(O)cc1	InChI=1S/C15H15N3O/c1-17(2)15-14(11-6-8-12(19)9-7-11)18-10-4-3-5-13(18)16-15/h3-10,19H,1-2H3	WHEMRCRGZRRMCK-UHFFFAOYSA-N	50560583	CHEMBL4740119	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560583&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162644832	461830975							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387464	CNc1nc2ccccn2c1-c1ccc(O)cc1	InChI=1S/C14H13N3O/c1-15-14-13(10-5-7-11(18)8-6-10)17-9-3-2-4-12(17)16-14/h2-9,15,18H,1H3	ONWWLRMGUGCQPX-UHFFFAOYSA-N	50560584	CHEMBL4755647	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560584&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162655788	461830976							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387465	CC(C)Nc1nc2ccccn2c1-c1ccc(O)cc1	InChI=1S/C16H17N3O/c1-11(2)17-16-15(12-6-8-13(20)9-7-12)19-10-4-3-5-14(19)18-16/h3-11,17,20H,1-2H3	KPRMDZKEUJUSHL-UHFFFAOYSA-N	50560585	CHEMBL4787231	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560585&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162667524	461830977							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387466	COc1ccc(cc1)-c1c(N)nc2ccccn12	InChI=1S/C14H13N3O/c1-18-11-7-5-10(6-8-11)13-14(15)16-12-4-2-3-9-17(12)13/h2-9H,15H2,1H3	MNCYUOVVWYBEPH-UHFFFAOYSA-N	50560586	CHEMBL4777703	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560586&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162644222	461830978							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387467	Nc1nc2ccc(cn2c1-c1ccc(O)cc1)C(F)(F)F	InChI=1S/C14H10F3N3O/c15-14(16,17)9-3-6-11-19-13(18)12(20(11)7-9)8-1-4-10(21)5-2-8/h1-7,21H,18H2	SMPHIZIMCUNGCX-UHFFFAOYSA-N	50560587	CHEMBL4745914	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560587&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162649001	461830979							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387468	Nc1nc2cc(ccn2c1-c1ccc(O)cc1)C(F)(F)F	InChI=1S/C14H10F3N3O/c15-14(16,17)9-5-6-20-11(7-9)19-13(18)12(20)8-1-3-10(21)4-2-8/h1-7,21H,18H2	PJSOHMVQJSKKKZ-UHFFFAOYSA-N	50560588	CHEMBL4761706	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560588&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162659264	461830980							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387469	Nc1nc2c(cccn2c1-c1ccc(O)cc1)C(F)(F)F	InChI=1S/C14H10F3N3O/c15-14(16,17)10-2-1-7-20-11(12(18)19-13(10)20)8-3-5-9(21)6-4-8/h1-7,21H,18H2	RYEVIPXNKCCETQ-UHFFFAOYSA-N	50560589	CHEMBL4745448	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560589&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162648378	461830981							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387470	Cc1ccc2nc(N)c(-c3ccc(O)cc3)n2c1	InChI=1S/C14H13N3O/c1-9-2-7-12-16-14(15)13(17(12)8-9)10-3-5-11(18)6-4-10/h2-8,18H,15H2,1H3	YOUVJLAWWDUBRV-UHFFFAOYSA-N	50560590	CHEMBL4743789	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560590&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162647214	461830982							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387471	Cc1ccn2c(c(N)nc2c1)-c1ccc(O)cc1	InChI=1S/C14H13N3O/c1-9-6-7-17-12(8-9)16-14(15)13(17)10-2-4-11(18)5-3-10/h2-8,18H,15H2,1H3	MUCQSAHJCJDIRZ-UHFFFAOYSA-N	50560591	CHEMBL4781213	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560591&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162662376	461830983							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387472	Cc1cccn2c(c(N)nc12)-c1ccc(O)cc1	InChI=1S/C14H13N3O/c1-9-3-2-8-17-12(13(15)16-14(9)17)10-4-6-11(18)7-5-10/h2-8,18H,15H2,1H3	BPUGMMFDXGULNQ-UHFFFAOYSA-N	50560592	CHEMBL4742897	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560592&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162645533	461830984							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51387473	Nc1nc2cc(ccn2c1-c1ccc(O)cc1)C1CCNCC1	InChI=1S/C18H20N4O/c19-18-17(13-1-3-15(23)4-2-13)22-10-7-14(11-16(22)21-18)12-5-8-20-9-6-12/h1-4,7,10-12,20,23H,5-6,8-9,19H2	QLLUGWVQQIMUDR-UHFFFAOYSA-N	50560593	CHEMBL4777381	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2020.127471	10.7270/Q20P13R0	32781219			Engström, O; Belda, O; Kullman-Magnusson, M; Rapp, M; Böhm, K; Paul, R; Henderson, I; Derbyshire, D; Karlström, S; Parkes, KEB; Zhao, H	Medivir AB	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560593&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			162643898	461830985							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137533	COc1cnc2c(C(=O)CN3CCC(CN(C)C)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C26H31N5O2/c1-18-25(24(32)17-30-11-9-20(10-12-30)16-29(2)3)26-23(13-22(33-4)15-28-26)31(18)21-7-5-19(14-27)6-8-21/h5-8,13,15,20H,9-12,16-17H2,1-4H3	NQWRKNAFVRWFET-UHFFFAOYSA-N	536670	US11242361, Compound 370	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536670&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085973	464921800							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137534	Cc1c(C(=O)CN2CCC(CC(O)=O)CC2)c2ncc(Br)cc2n1-c1ccc(Cl)cc1	InChI=1S/C23H23BrClN3O3/c1-14-22(20(29)13-27-8-6-15(7-9-27)10-21(30)31)23-19(11-16(24)12-26-23)28(14)18-4-2-17(25)3-5-18/h2-5,11-12,15H,6-10,13H2,1H3,(H,30,31)	NUWZXVYNEGGQTR-UHFFFAOYSA-N	536671	US11242361, Compound 371	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536671&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085771	464921801							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137535	FC(F)(F)c1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(cc1)C#N	InChI=1S/C22H19F3N4O/c23-22(24,25)21-19(18(30)14-28-11-2-1-3-12-28)20-17(5-4-10-27-20)29(21)16-8-6-15(13-26)7-9-16/h4-10H,1-3,11-12,14H2	RMDYUFCZOPTEBO-UHFFFAOYSA-N	536672	US11242361, Compound 372	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536672&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085787	464921802							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137536	C[C@@H]1CCC[C@@H](C)N1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C24H25BrN4O/c1-15-5-4-6-16(2)28(15)14-22(30)23-17(3)29(20-9-7-18(12-26)8-10-20)21-11-19(25)13-27-24(21)23/h7-11,13,15-16H,4-6,14H2,1-3H3/t15-,16-/m1/s1	NNLIGZDVWWNKQK-HZPDHXFCSA-N	536673	US11242361, Compound 373	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536673&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085777	464921803							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137537	C[C@H]1CCC[C@H](C)N1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C24H25BrN4O/c1-15-5-4-6-16(2)28(15)14-22(30)23-17(3)29(20-9-7-18(12-26)8-10-20)21-11-19(25)13-27-24(21)23/h7-11,13,15-16H,4-6,14H2,1-3H3/t15-,16-/m0/s1	NNLIGZDVWWNKQK-HOTGVXAUSA-N	536674	US11242361, Compound 374	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536674&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085781	464921804							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137538	Cc1c(C(=O)CN2CCCCC2)c2ncc(CC(=O)NC3CC3)cc2n1-c1ccc(cc1)C#N	InChI=1S/C27H29N5O2/c1-18-26(24(33)17-31-11-3-2-4-12-31)27-23(32(18)22-9-5-19(15-28)6-10-22)13-20(16-29-27)14-25(34)30-21-7-8-21/h5-6,9-10,13,16,21H,2-4,7-8,11-12,14,17H2,1H3,(H,30,34)	KMEWPDXSSNNIPI-UHFFFAOYSA-N	536675	US11242361, Compound 381	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536675&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078489	464921805							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137539	CCN(C)C(=O)Cc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C27H31N5O2/c1-4-30(3)25(34)15-21-14-23-27(29-17-21)26(24(33)18-31-12-6-5-7-13-31)19(2)32(23)22-10-8-20(16-28)9-11-22/h8-11,14,17H,4-7,12-13,15,18H2,1-3H3	SDBVNRLLZCKQIZ-UHFFFAOYSA-N	536676	US11242361, Compound 382	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536676&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078636	464921806							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137540	CCNC(=O)Cc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C26H29N5O2/c1-3-28-24(33)14-20-13-22-26(29-16-20)25(23(32)17-30-11-5-4-6-12-30)18(2)31(22)21-9-7-19(15-27)8-10-21/h7-10,13,16H,3-6,11-12,14,17H2,1-2H3,(H,28,33)	FOBIBENWTIMTLQ-UHFFFAOYSA-N	536677	US11242361, Compound 383	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536677&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078615	464921807							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137541	CCOC(=O)Cc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C26H28N4O3/c1-3-33-24(32)14-20-13-22-26(28-16-20)25(23(31)17-29-11-5-4-6-12-29)18(2)30(22)21-9-7-19(15-27)8-10-21/h7-10,13,16H,3-6,11-12,14,17H2,1-2H3	ATOWYGZWLMLWQZ-UHFFFAOYSA-N	536678	US11242361, Compound 384	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536678&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078483	464921808							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137542	Cc1c(C(=O)CN2CCCCC2)c2ncc(Cl)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21ClN4O/c1-15-21(20(28)14-26-9-3-2-4-10-26)22-19(11-17(23)13-25-22)27(15)18-7-5-16(12-24)6-8-18/h5-8,11,13H,2-4,9-10,14H2,1H3	BRTKWYCTLKPMQH-UHFFFAOYSA-N	536679	US11242361, Compound 385	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536679&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085772	464921809							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137543	Cc1c(C(=O)CN2CCC(CNCC(O)=O)CC2)c2ncc(Br)cc2n1-c1ccc(Cl)cc1	InChI=1S/C24H26BrClN4O3/c1-15-23(21(31)14-29-8-6-16(7-9-29)11-27-13-22(32)33)24-20(10-17(25)12-28-24)30(15)19-4-2-18(26)3-5-19/h2-5,10,12,16,27H,6-9,11,13-14H2,1H3,(H,32,33)	IQAVEZCBXKLUHE-UHFFFAOYSA-N	536680	US11242361, Compound 386	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536680&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085788	464921810							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137544	CCCC(=O)CCc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C27H32ClN3O2/c1-3-7-23(32)13-8-20-16-24-27(29-17-20)26(25(33)18-30-14-5-4-6-15-30)19(2)31(24)22-11-9-21(28)10-12-22/h9-12,16-17H,3-8,13-15,18H2,1-2H3	BMIJWOBSKPJLGH-UHFFFAOYSA-N	536681	US11242361, Compound 387	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536681&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085789	464921811							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137545	Cc1c(C(=O)CN2CCC(O)CC2)c2ncccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H22ClN3O2/c1-14-20(19(27)13-24-11-8-17(26)9-12-24)21-18(3-2-10-23-21)25(14)16-6-4-15(22)5-7-16/h2-7,10,17,26H,8-9,11-13H2,1H3	KWKKGJHYSOUYMR-UHFFFAOYSA-N	536682	US11242361, Compound 388	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536682&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085790	464921812							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137546	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(F)cc1	InChI=1S/C22H23FN2O2/c1-15-22(21(27)14-24-12-10-18(26)11-13-24)19-4-2-3-5-20(19)25(15)17-8-6-16(23)7-9-17/h2-9,18,26H,10-14H2,1H3	GSRVSNAINUVRDH-UHFFFAOYSA-N	536683	US11242361, Compound 389	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536683&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086029	464921813							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137547	Cc1c(C(=O)CN2CCC(O)(CC2)C(F)(F)F)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C23H22ClF3N2O2/c1-15-21(20(30)14-28-12-10-22(31,11-13-28)23(25,26)27)18-4-2-3-5-19(18)29(15)17-8-6-16(24)7-9-17/h2-9,31H,10-14H2,1H3	NFMLUSUPJLVHHT-UHFFFAOYSA-N	536684	US11242361, Compound 390	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536684&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085833	464921814							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137548	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(F)c(F)c1	InChI=1S/C22H22F2N2O2/c1-14-22(21(28)13-25-10-8-16(27)9-11-25)17-4-2-3-5-20(17)26(14)15-6-7-18(23)19(24)12-15/h2-7,12,16,27H,8-11,13H2,1H3	MSVUXDIOZMXRBV-UHFFFAOYSA-N	536685	US11242361, Compound 391	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536685&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085827	464921815							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137549	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(Cl)nc1	InChI=1S/C21H22ClN3O2/c1-14-21(19(27)13-24-10-8-16(26)9-11-24)17-4-2-3-5-18(17)25(14)15-6-7-20(22)23-12-15/h2-7,12,16,26H,8-11,13H2,1H3	LHVPJWUYVYXERY-UHFFFAOYSA-N	536686	US11242361, Compound 392	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536686&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085828	464921816							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137550	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(nc1)C#N	InChI=1S/C22H22N4O2/c1-15-22(21(28)14-25-10-8-18(27)9-11-25)19-4-2-3-5-20(19)26(15)17-7-6-16(12-23)24-13-17/h2-7,13,18,27H,8-11,14H2,1H3	LEPGGJQMMBSQOK-UHFFFAOYSA-N	536687	US11242361, Compound 393	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536687&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085829	464921817							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137551	Cc1c(C(=O)CN2CCC(O)CC2)c2ccc(F)cc2n1-c1ccc(Cl)cc1	InChI=1S/C22H22ClFN2O2/c1-14-22(21(28)13-25-10-8-18(27)9-11-25)19-7-4-16(24)12-20(19)26(14)17-5-2-15(23)3-6-17/h2-7,12,18,27H,8-11,13H2,1H3	OSGJITFISNDPHL-UHFFFAOYSA-N	536688	US11242361, Compound 394	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536688&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085830	464921818							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137552	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1cccnc1	InChI=1S/C21H23N3O2/c1-15-21(20(26)14-23-11-8-17(25)9-12-23)18-6-2-3-7-19(18)24(15)16-5-4-10-22-13-16/h2-7,10,13,17,25H,8-9,11-12,14H2,1H3	TXBRZNFKEZFHDI-UHFFFAOYSA-N	536689	US11242361, Compound 395	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536689&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085826	464921819							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137553	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccncc1	InChI=1S/C21H23N3O2/c1-15-21(20(26)14-23-12-8-17(25)9-13-23)18-4-2-3-5-19(18)24(15)16-6-10-22-11-7-16/h2-7,10-11,17,25H,8-9,12-14H2,1H3	FUZZXUCMGFSHJQ-UHFFFAOYSA-N	536690	US11242361, Compound 396	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536690&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085839	464921820							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137554	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccccn1	InChI=1S/C21H23N3O2/c1-15-21(19(26)14-23-12-9-16(25)10-13-23)17-6-2-3-7-18(17)24(15)20-8-4-5-11-22-20/h2-8,11,16,25H,9-10,12-14H2,1H3	GFNLZBVEXNJZMX-UHFFFAOYSA-N	536691	US11242361, Compound 397	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536691&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085838	464921821							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137555	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(Cl)cn1	InChI=1S/C21H22ClN3O2/c1-14-21(19(27)13-24-10-8-16(26)9-11-24)17-4-2-3-5-18(17)25(14)20-7-6-15(22)12-23-20/h2-7,12,16,26H,8-11,13H2,1H3	YXLKTCFPXHFTNW-UHFFFAOYSA-N	536692	US11242361, Compound 398	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536692&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085841	464921822							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137556	Clc1ccc(cc1)-n1c(C2CC2)c(C(=O)CN2CCCCC2)c2ccccc12	InChI=1S/C24H25ClN2O/c25-18-10-12-19(13-11-18)27-21-7-3-2-6-20(21)23(24(27)17-8-9-17)22(28)16-26-14-4-1-5-15-26/h2-3,6-7,10-13,17H,1,4-5,8-9,14-16H2	UBRHYDYDUWVPPS-UHFFFAOYSA-N	536693	US11242361, Compound 399	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536693&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085840	464921823							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137557	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ncc(Cl)cn1	InChI=1S/C20H21ClN4O2/c1-13-19(18(27)12-24-8-6-15(26)7-9-24)16-4-2-3-5-17(16)25(13)20-22-10-14(21)11-23-20/h2-5,10-11,15,26H,6-9,12H2,1H3	DPQVJRSEXODZBL-UHFFFAOYSA-N	536694	US11242361, Compound 400	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085842	464921824							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137558	CCc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C23H25ClN2O/c1-2-20-23(22(27)16-25-14-6-3-7-15-25)19-8-4-5-9-21(19)26(20)18-12-10-17(24)11-13-18/h4-5,8-13H,2-3,6-7,14-16H2,1H3	HLVBJXSZQDFCMM-UHFFFAOYSA-N	536695	US11242361, Compound 401	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536695&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085947	464921825							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137559	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ncc(Cl)s1	InChI=1S/C19H20ClN3O2S/c1-12-18(16(25)11-22-8-6-13(24)7-9-22)14-4-2-3-5-15(14)23(12)19-21-10-17(20)26-19/h2-5,10,13,24H,6-9,11H2,1H3	HFDLGBBHEYDEDJ-UHFFFAOYSA-N	536696	US11242361, Compound 402	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536696&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085946	464921826							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137383	OC1CCN(CC(=O)c2cn(-c3ccc(Cl)cc3)c3ccccc23)CC1	InChI=1S/C21H21ClN2O2/c22-15-5-7-16(8-6-15)24-13-19(18-3-1-2-4-20(18)24)21(26)14-23-11-9-17(25)10-12-23/h1-8,13,17,25H,9-12,14H2	MXSGOXXVDYLZSE-UHFFFAOYSA-N	536520	US11242361, Compound 30	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536520&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			71007035	464921653							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137384	Clc1ccc(cc1)-n1cc(C(=O)CN2CCCCC2)c2ccccc12	InChI=1S/C21H21ClN2O/c22-16-8-10-17(11-9-16)24-14-19(18-6-2-3-7-20(18)24)21(25)15-23-12-4-1-5-13-23/h2-3,6-11,14H,1,4-5,12-13,15H2	PHJJFMGRYXRVSE-UHFFFAOYSA-N	536521	US11242361, Compound 31	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536521&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			71007033	464921654							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137385	Clc1ccc(cc1)-n1cc(C(=O)CN2CCCC2)c2ccccc12	InChI=1S/C20H19ClN2O/c21-15-7-9-16(10-8-15)23-13-18(17-5-1-2-6-19(17)23)20(24)14-22-11-3-4-12-22/h1-2,5-10,13H,3-4,11-12,14H2	AWRAQEMTXLUKAO-UHFFFAOYSA-N	536522	US11242361, Compound 34	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536522&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			70984365	464921655							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137386	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C22H23ClN2O2/c1-15-22(21(27)14-24-12-10-18(26)11-13-24)19-4-2-3-5-20(19)25(15)17-8-6-16(23)7-9-17/h2-9,18,26H,10-14H2,1H3	AFVDNXKPRDHARM-UHFFFAOYSA-N	536523	US11242361, Compound 86	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536523&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			71087712	464921656							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137387	Cc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C22H23ClN2O/c1-16-22(21(26)15-24-13-5-2-6-14-24)19-7-3-4-8-20(19)25(16)18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-15H2,1H3	YOZPAJNIWRKUDY-UHFFFAOYSA-N	536524	US11242361, Compound 87	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536524&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			70984779	464921657							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137388	Cc1c(C(=O)CN2CCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H21ClN2O/c1-15-21(20(25)14-23-12-4-5-13-23)18-6-2-3-7-19(18)24(15)17-10-8-16(22)9-11-17/h2-3,6-11H,4-5,12-14H2,1H3	OJRCHFCIXAZBJC-UHFFFAOYSA-N	536525	US11242361, Compound 88	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536525&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			70984318	464921658							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137389	Cc1c(C(=O)CN2CCCCC2)c2cc(F)ccc2n1-c1ccc(Cl)cc1	InChI=1S/C22H22ClFN2O/c1-15-22(21(27)14-25-11-3-2-4-12-25)19-13-17(24)7-10-20(19)26(15)18-8-5-16(23)6-9-18/h5-10,13H,2-4,11-12,14H2,1H3	CIIVLVUFOANQQR-UHFFFAOYSA-N	536526	US11242361, Compound 98	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536526&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085808	464921659							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137390	Cc1c(C(O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C22H25ClN2O/c1-16-22(21(26)15-24-13-5-2-6-14-24)19-7-3-4-8-20(19)25(16)18-11-9-17(23)10-12-18/h3-4,7-12,21,26H,2,5-6,13-15H2,1H3	RHWCOLCLBKNEDA-UHFFFAOYSA-N	536527	US11242361, Compound 106	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536527&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085807	464921660							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137391	Cc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(cc1)C(N)=O	InChI=1S/C23H25N3O2/c1-16-22(21(27)15-25-13-5-2-6-14-25)19-7-3-4-8-20(19)26(16)18-11-9-17(10-12-18)23(24)28/h3-4,7-12H,2,5-6,13-15H2,1H3,(H2,24,28)	IGDNPXXKYGGIHV-UHFFFAOYSA-N	536528	US11242361, Compound 108	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536528&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085809	464921661							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137392	OCc1ccc2c(cn(-c3ccc(Cl)cc3)c2c1)C(=O)CN1CCCCC1	InChI=1S/C22H23ClN2O2/c23-17-5-7-18(8-6-17)25-13-20(19-9-4-16(15-26)12-21(19)25)22(27)14-24-10-2-1-3-11-24/h4-9,12-13,26H,1-3,10-11,14-15H2	SQFUVYILBPOGIH-UHFFFAOYSA-N	536529	US11242361, Compound 115	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536529&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078602	464921662							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137393	Cc1c(C(=O)CC2CCCCC2)c2ncccc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23N3O/c1-16-22(21(27)14-17-6-3-2-4-7-17)23-20(8-5-13-25-23)26(16)19-11-9-18(15-24)10-12-19/h5,8-13,17H,2-4,6-7,14H2,1H3	DXHNCLWCQRYVAO-UHFFFAOYSA-N	536530	4-[2-Methyl-3-(2-piperidin-1-yl-acetyl)-pyrrolo[3,2-b]pyridin-1-yl]-benzonitrile ::US11242361, Compound 116	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536530&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085765	464921663							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137394	CC(=O)OCc1ccc2c(cn(-c3ccc(Cl)cc3)c2c1)C(=O)CN1CCCCC1	InChI=1S/C24H25ClN2O3/c1-17(28)30-16-18-5-10-21-22(24(29)15-26-11-3-2-4-12-26)14-27(23(21)13-18)20-8-6-19(25)7-9-20/h5-10,13-14H,2-4,11-12,15-16H2,1H3	QAMOQYZRZOCSRU-UHFFFAOYSA-N	536531	US11242361, Compound 118	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536531&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078687	464921664							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137395	CNCc1ccc2c(cn(-c3ccc(Cl)cc3)c2c1)C(=O)CN1CCCCC1	InChI=1S/C23H26ClN3O/c1-25-14-17-5-10-20-21(23(28)16-26-11-3-2-4-12-26)15-27(22(20)13-17)19-8-6-18(24)7-9-19/h5-10,13,15,25H,2-4,11-12,14,16H2,1H3	PNEPUELWFJFZLM-UHFFFAOYSA-N	536532	US11242361, Compound 119	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536532&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078686	464921665							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137396	Oc1ccc2c(cn(-c3ccc(Cl)cc3)c2c1)C(=O)CN1CCCCC1	InChI=1S/C21H21ClN2O2/c22-15-4-6-16(7-5-15)24-13-19(18-9-8-17(25)12-20(18)24)21(26)14-23-10-2-1-3-11-23/h4-9,12-13,25H,1-3,10-11,14H2	URISJLMNRNQJMY-UHFFFAOYSA-N	536533	US11242361, Compound 120	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536533&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085766	464921666							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137397	COC(=O)c1ccc2c(C(O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C24H27ClN2O3/c1-16-23(22(28)15-26-12-4-3-5-13-26)20-11-6-17(24(29)30-2)14-21(20)27(16)19-9-7-18(25)8-10-19/h6-11,14,22,28H,3-5,12-13,15H2,1-2H3	IBENJKCNBMACNV-UHFFFAOYSA-N	536534	US11242361, Compound 126	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536534&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078566	464921667							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137398	Cc1c(C(=O)CN2CCCCC2)c2nc(O)ccc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O2/c1-15-21(19(27)14-25-11-3-2-4-12-25)22-18(9-10-20(28)24-22)26(15)17-7-5-16(13-23)6-8-17/h5-10H,2-4,11-12,14H2,1H3,(H,24,28)	GITXDHMQQUWILB-UHFFFAOYSA-N	536535	US11242361, Compound 127	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536535&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085844	464921668							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137399	Cc1[nH]c2cccnc2c1C(=O)CN1CCCCC1	InChI=1S/C15H19N3O/c1-11-14(15-12(17-11)6-5-7-16-15)13(19)10-18-8-3-2-4-9-18/h5-7,17H,2-4,8-10H2,1H3	XQHGWMFJQSUXFH-UHFFFAOYSA-N	536536	1-(2-Methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)-2-(piperidin-1-yl)ethan-1-one ::US11242361, Compound 128	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536536&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078508	464921669							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137400	Cc1c(C(O)CN2CCCCC2)c2ccc(CO)cc2n1-c1ccc(Cl)cc1	InChI=1S/C23H27ClN2O2/c1-16-23(22(28)14-25-11-3-2-4-12-25)20-10-5-17(15-27)13-21(20)26(16)19-8-6-18(24)7-9-19/h5-10,13,22,27-28H,2-4,11-12,14-15H2,1H3	YOZOOCGGLBXNSR-UHFFFAOYSA-N	536537	US11242361, Compound 130	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536537&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078523	464921670							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137401	Oc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H21ClN2O2/c22-15-8-10-16(11-9-15)24-18-7-3-2-6-17(18)20(21(24)26)19(25)14-23-12-4-1-5-13-23/h2-3,6-11,26H,1,4-5,12-14H2	CSXMPEMWDCIUFG-UHFFFAOYSA-N	536538	US11242361, Compound 131	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536538&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			136987138	464921671							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137402	COc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C22H23ClN2O2/c1-27-22-21(20(26)15-24-13-5-2-6-14-24)18-7-3-4-8-19(18)25(22)17-11-9-16(23)10-12-17/h3-4,7-12H,2,5-6,13-15H2,1H3	OGSOIQUVGZAMNZ-UHFFFAOYSA-N	536539	US11242361, Compound 132	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536539&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078556	464921672							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137403	CCOC(=O)CCc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C28H31N3O3/c1-3-34-27(33)14-10-21-9-13-24-25(17-21)31(23-11-7-22(18-29)8-12-23)20(2)28(24)26(32)19-30-15-5-4-6-16-30/h7-9,11-13,17H,3-6,10,14-16,19H2,1-2H3	SHEYAJSULIJADO-UHFFFAOYSA-N	536540	US11242361, Compound 133	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536540&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078586	464921673							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137404	Cc1c(C(=O)CN2CCCCC2)c2cccnc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O/c1-16-21(20(27)15-25-12-3-2-4-13-25)19-6-5-11-24-22(19)26(16)18-9-7-17(14-23)8-10-18/h5-11H,2-4,12-13,15H2,1H3	YBVBATZLIGNEGH-UHFFFAOYSA-N	536541	4-(2-Methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 141	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536541&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078683	464921674							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137405	Cc1c(C(=O)CN2CCC(CC2)NC(=O)OC(C)(C)C)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C27H32ClN3O3/c1-18-25(22-7-5-6-8-23(22)31(18)21-11-9-19(28)10-12-21)24(32)17-30-15-13-20(14-16-30)29-26(33)34-27(2,3)4/h5-12,20H,13-17H2,1-4H3,(H,29,33)	KEBALFBGCXLFMI-UHFFFAOYSA-N	536542	US11242361, Compound 142	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536542&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086073	464921675							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137406	Cc1c(C(=O)CN2CCCCC2)c2ccncc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O/c1-16-22(21(27)15-25-11-3-2-4-12-25)19-9-10-24-14-20(19)26(16)18-7-5-17(13-23)6-8-18/h5-10,14H,2-4,11-12,15H2,1H3	WKHNURGOUMLCSX-UHFFFAOYSA-N	536543	4-(2-Methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[2,3-c]pyridin-1-yl)benzonitrile ::US11242361, Compound 144	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536543&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078538	464921676							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137407	Cc1c(C(=O)CN2CCCCC2)c2cc(Oc3ccccc3)ccc2n1-c1ccc(Cl)cc1	InChI=1S/C28H27ClN2O2/c1-20-28(27(32)19-30-16-6-3-7-17-30)25-18-24(33-23-8-4-2-5-9-23)14-15-26(25)31(20)22-12-10-21(29)11-13-22/h2,4-5,8-15,18H,3,6-7,16-17,19H2,1H3	BSLCNUNKFXEDSL-UHFFFAOYSA-N	536544	US11242361, Compound 145	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536544&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085767	464921677							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137408	COc1cccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c12	InChI=1S/C24H25N3O2/c1-17-23(21(28)16-26-13-4-3-5-14-26)20-7-6-8-22(29-2)24(20)27(17)19-11-9-18(15-25)10-12-19/h6-12H,3-5,13-14,16H2,1-2H3	AGKHLDOEVVZMMV-UHFFFAOYSA-N	536545	US11242361, Compound 146	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536545&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085897	464921678							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137409	Cc1c(C(=O)CN2CCC(CC2)NC(=O)c2ccc(cc2)N=[N+]=[N-])c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C29H27ClN6O2/c1-19-28(25-4-2-3-5-26(25)36(19)24-12-8-21(30)9-13-24)27(37)18-35-16-14-22(15-17-35)32-29(38)20-6-10-23(11-7-20)33-34-31/h2-13,22H,14-18H2,1H3,(H,32,38)	NROMJVVVBRIEMN-UHFFFAOYSA-N	536546	US11242361, Compound 147	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536546&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085894	464921679							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137410	Cc1c(C(=O)CN2CCCCC2)c2ccc(O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C22H23ClN2O2/c1-15-22(21(27)14-24-11-3-2-4-12-24)19-10-9-18(26)13-20(19)25(15)17-7-5-16(23)6-8-17/h5-10,13,26H,2-4,11-12,14H2,1H3	HULJEQVFZHSYPA-UHFFFAOYSA-N	536547	US11242361, Compound 148	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536547&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078532	464921680							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137411	Cc1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(Cl)nc1	InChI=1S/C20H21ClN4O/c1-14-19(17(26)13-24-10-3-2-4-11-24)20-16(6-5-9-22-20)25(14)15-7-8-18(21)23-12-15/h5-9,12H,2-4,10-11,13H2,1H3	WTWXVLMVFXUKLF-UHFFFAOYSA-N	536548	US11242361, Compound 149	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536548&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085896	464921681							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137412	Cc1c(C(=O)CN2CCCCC2)c2cc(ccc2n1-c1ccc(Cl)cc1)[N+]([O-])=O	InChI=1S/C22H22ClN3O3/c1-15-22(21(27)14-24-11-3-2-4-12-24)19-13-18(26(28)29)9-10-20(19)25(15)17-7-5-16(23)6-8-17/h5-10,13H,2-4,11-12,14H2,1H3	RCKOLQJNXZTWCC-UHFFFAOYSA-N	536549	US11242361, Compound 150	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536549&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085847	464921682							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137413	Cc1c(C(=O)CN2CCCCC2)c2cnccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H22ClN3O/c1-15-21(20(26)14-24-11-3-2-4-12-24)18-13-23-10-9-19(18)25(15)17-7-5-16(22)6-8-17/h5-10,13H,2-4,11-12,14H2,1H3	KLGYYKNHYDZJSW-UHFFFAOYSA-N	536550	4-(2-Methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-c]pyridin-1-yl)benzonitrile ::US11242361, Compound 151	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536550&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085851	464921683							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137414	Cc1c(C(=O)CN2CCCCC2)c2ccc(CN3C(=O)c4ccccc4C3=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C31H28ClN3O3/c1-20-29(28(36)19-33-15-5-2-6-16-33)26-14-9-21(17-27(26)35(20)23-12-10-22(32)11-13-23)18-34-30(37)24-7-3-4-8-25(24)31(34)38/h3-4,7-14,17H,2,5-6,15-16,18-19H2,1H3	KTARJSIAFKABCQ-UHFFFAOYSA-N	536551	US11242361, Compound 152	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536551&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085849	464921684							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137415	Cc1c(C(=O)CN2CCCCC2)c2ccc(CO[Si](C)(C)C(C)(C)C)cc2n1-c1ccc(Cl)cc1	InChI=1S/C29H39ClN2O2Si/c1-21-28(27(33)19-31-16-8-7-9-17-31)25-15-10-22(20-34-35(5,6)29(2,3)4)18-26(25)32(21)24-13-11-23(30)12-14-24/h10-15,18H,7-9,16-17,19-20H2,1-6H3	VBBXYPZMUUQNJS-UHFFFAOYSA-N	536552	US11242361, Compound 153	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536552&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			123856807	464921685							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137416	COc1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2c1)-c1ccc(Cl)cc1	InChI=1S/C23H25ClN2O2/c1-16-23(22(27)15-25-12-4-3-5-13-25)20-14-19(28-2)10-11-21(20)26(16)18-8-6-17(24)7-9-18/h6-11,14H,3-5,12-13,15H2,1-2H3	FKIRIUGPFPXJSA-UHFFFAOYSA-N	536553	US11242361, Compound 155	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536553&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085850	464921686							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137417	Cc1c(C(=O)CN2CCCCC2)c2cc(C)ccc2n1-c1ccc(Cl)cc1	InChI=1S/C23H25ClN2O/c1-16-6-11-21-20(14-16)23(22(27)15-25-12-4-3-5-13-25)17(2)26(21)19-9-7-18(24)8-10-19/h6-11,14H,3-5,12-13,15H2,1-2H3	ULYYGSXMPIXVFW-UHFFFAOYSA-N	536554	US11242361, Compound 156	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536554&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085913	464921687							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137418	Cc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23N3O/c1-17-23(22(27)16-25-13-5-2-6-14-25)20-7-3-4-8-21(20)26(17)19-11-9-18(15-24)10-12-19/h3-4,7-12H,2,5-6,13-14,16H2,1H3	RJGCPDQPUDQZPB-UHFFFAOYSA-N	536555	US11242361, Compound 160	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536555&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078501	464921688							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137419	Cc1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H22ClN3O/c1-15-20(19(26)14-24-12-3-2-4-13-24)21-18(6-5-11-23-21)25(15)17-9-7-16(22)8-10-17/h5-11H,2-4,12-14H2,1H3	GOPAVOQRIAXBOU-UHFFFAOYSA-N	536556	US11242361, Compound 161	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536556&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085899	464921689							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137420	Cc1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O/c1-16-21(20(27)15-25-12-3-2-4-13-25)22-19(6-5-11-24-22)26(16)18-9-7-17(14-23)8-10-18/h5-11H,2-4,12-13,15H2,1H3	SMVBBOFEDZDCHU-UHFFFAOYSA-N	536557	4-(2-Methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 162	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536557&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078512	464921690							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137421	Cc1c(C(=O)CN2CCCCC2)c2cc(ccc2n1-c1ccc(cc1)C#N)C#N	InChI=1S/C24H22N4O/c1-17-24(23(29)16-27-11-3-2-4-12-27)21-13-19(15-26)7-10-22(21)28(17)20-8-5-18(14-25)6-9-20/h5-10,13H,2-4,11-12,16H2,1H3	VUGGEZOPEKQIPE-UHFFFAOYSA-N	536558	US11242361, Compound 163	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536558&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085898	464921691							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137422	Cc1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C22H23N3O3/c1-16-22(21(26)15-23-13-5-2-6-14-23)19-7-3-4-8-20(19)24(16)17-9-11-18(12-10-17)25(27)28/h3-4,7-12H,2,5-6,13-15H2,1H3	UGQCDLJKEHQPFP-UHFFFAOYSA-N	536559	US11242361, Compound 164	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536559&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085901	464921692							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137423	Cc1c(C(=O)CN2CCCCC2)c2nc(F)ccc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21FN4O/c1-15-21(19(28)14-26-11-3-2-4-12-26)22-18(9-10-20(23)25-22)27(15)17-7-5-16(13-24)6-8-17/h5-10H,2-4,11-12,14H2,1H3	PAHNFXWEQGBTOD-UHFFFAOYSA-N	536560	US11242361, Compound 165	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536560&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085900	464921693							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137424	COc1cccc2n(c(C)c(C(=O)CN3CCCCC3)c12)-c1ccc(cc1)C#N	InChI=1S/C24H25N3O2/c1-17-23(21(28)16-26-13-4-3-5-14-26)24-20(7-6-8-22(24)29-2)27(17)19-11-9-18(15-25)10-12-19/h6-12H,3-5,13-14,16H2,1-2H3	OLKASIHFMYZDAI-UHFFFAOYSA-N	536561	US11242361, Compound 167	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536561&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085903	464921694							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137425	Cc1c(C(=O)CN2CCCCC2)c2c(F)cccc2n1-c1ccc(cc1)C#N	InChI=1S/C23H22FN3O/c1-16-22(21(28)15-26-12-3-2-4-13-26)23-19(24)6-5-7-20(23)27(16)18-10-8-17(14-25)9-11-18/h5-11H,2-4,12-13,15H2,1H3	FULWCQCKRLHMHN-UHFFFAOYSA-N	536562	US11242361, Compound 168	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536562&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085902	464921695							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137426	Cc1c(C(=O)CN2CCCCC2)c2ccc(C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C24H25N3O/c1-17-6-11-21-22(14-17)27(20-9-7-19(15-25)8-10-20)18(2)24(21)23(28)16-26-12-4-3-5-13-26/h6-11,14H,3-5,12-13,16H2,1-2H3	ZKAHQEVNUJIOHX-UHFFFAOYSA-N	536563	4-(2,6-Dimethyl-3-(2-(piperidin-1-yl)acetyl)-1H-indol-1-yl)benzonitrile ::US11242361, Compound 169	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536563&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078500	464921696							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137427	Cc1c(C(=O)CN2CCCCC2)c2cccc(F)c2n1-c1ccc(cc1)C#N	InChI=1S/C23H22FN3O/c1-16-22(21(28)15-26-12-3-2-4-13-26)19-6-5-7-20(24)23(19)27(16)18-10-8-17(14-25)9-11-18/h5-11H,2-4,12-13,15H2,1H3	RUZSWSYBOJZQSS-UHFFFAOYSA-N	536564	US11242361, Compound 170	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536564&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085904	464921697							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137428	COC(=O)c1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C24H25ClN2O3/c1-16-23(22(28)15-26-12-4-3-5-13-26)20-11-6-17(24(29)30-2)14-21(20)27(16)19-9-7-18(25)8-10-19/h6-11,14H,3-5,12-13,15H2,1-2H3	DPLBOCDILSGPAF-UHFFFAOYSA-N	536565	US11242361, Compound 171	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536565&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085817	464921698							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137429	CC(=O)Oc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C24H25ClN2O3/c1-16-24(23(29)15-26-12-4-3-5-13-26)21-11-10-20(30-17(2)28)14-22(21)27(16)19-8-6-18(25)7-9-19/h6-11,14H,3-5,12-13,15H2,1-2H3	MUOXNYHOHLPGSH-UHFFFAOYSA-N	536566	US11242361, Compound 172	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536566&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078554	464921699							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137430	Cc1c(C(=O)CN2CCCCC2)c2nc(F)ccc2n1-c1ccc(Cl)cc1	InChI=1S/C21H21ClFN3O/c1-14-20(18(27)13-25-11-3-2-4-12-25)21-17(9-10-19(23)24-21)26(14)16-7-5-15(22)6-8-16/h5-10H,2-4,11-13H2,1H3	RHLKUQCRWMKGHE-UHFFFAOYSA-N	536567	US11242361, Compound 173	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536567&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085811	464921700							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137431	Cc1c(C(=O)CN2CCCCC2)c2ccc(cc2n1-c1ccc(cc1)C#N)C#N	InChI=1S/C24H22N4O/c1-17-24(23(29)16-27-11-3-2-4-12-27)21-10-7-19(15-26)13-22(21)28(17)20-8-5-18(14-25)6-9-20/h5-10,13H,2-4,11-12,16H2,1H3	CBAUMLXNVPWLMC-UHFFFAOYSA-N	536568	US11242361, Compound 175	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536568&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085812	464921701							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137432	Cc1c(C(=O)CN2CCCCC2)c2ccc(F)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H22FN3O/c1-16-23(22(28)15-26-11-3-2-4-12-26)20-10-7-18(24)13-21(20)27(16)19-8-5-17(14-25)6-9-19/h5-10,13H,2-4,11-12,15H2,1H3	RRAHECFKRGXWAG-UHFFFAOYSA-N	536569	US11242361, Compound 176	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536569&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085818	464921702							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137433	COc1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2n1)-c1ccc(cc1)C#N	InChI=1S/C23H24N4O2/c1-16-22(20(28)15-26-12-4-3-5-13-26)23-19(10-11-21(25-23)29-2)27(16)18-8-6-17(14-24)7-9-18/h6-11H,3-5,12-13,15H2,1-2H3	RCJHHJOROIZZOC-UHFFFAOYSA-N	536570	US11242361, Compound 177	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536570&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078585	464921703							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137434	COc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C23H25ClN2O2/c1-16-23(22(27)15-25-12-4-3-5-13-25)20-11-10-19(28-2)14-21(20)26(16)18-8-6-17(24)7-9-18/h6-11,14H,3-5,12-13,15H2,1-2H3	NLEWXEYTYNVLII-UHFFFAOYSA-N	536571	US11242361, Compound 178	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536571&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085914	464921704							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137435	Cc1c(C(=O)CN2CCCCC2)c2ccc(OCC(N)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C24H26ClN3O3/c1-16-24(22(29)14-27-11-3-2-4-12-27)20-10-9-19(31-15-23(26)30)13-21(20)28(16)18-7-5-17(25)6-8-18/h5-10,13H,2-4,11-12,14-15H2,1H3,(H2,26,30)	DIEBGKCEOQDLTR-UHFFFAOYSA-N	536572	US11242361, Compound 179	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536572&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078487	464921705							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137436	CC(C)c1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C26H29N3O/c1-18(2)21-9-12-23-24(15-21)29(22-10-7-20(16-27)8-11-22)19(3)26(23)25(30)17-28-13-5-4-6-14-28/h7-12,15,18H,4-6,13-14,17H2,1-3H3	DNMHZMZKKRGVPC-UHFFFAOYSA-N	536573	4-(6-Isopropyl-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-indol-1-yl)benzonitrile ::US11242361, Compound 180	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536573&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078592	464921706							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137437	Cc1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(nc1)C#N	InChI=1S/C21H21N5O/c1-15-20(19(27)14-25-10-3-2-4-11-25)21-18(6-5-9-23-21)26(15)17-8-7-16(12-22)24-13-17/h5-9,13H,2-4,10-11,14H2,1H3	PEQUWKKPMBJPLP-UHFFFAOYSA-N	536574	US11242361, Compound 181	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536574&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078587	464921707							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137438	Cc1c(C(=O)CN2CCCCC2)c2ccc(CO)cc2n1-c1ccc(Cl)cc1	InChI=1S/C23H25ClN2O2/c1-16-23(22(28)14-25-11-3-2-4-12-25)20-10-5-17(15-27)13-21(20)26(16)19-8-6-18(24)7-9-19/h5-10,13,27H,2-4,11-12,14-15H2,1H3	XKUUIMMBSZCDLO-UHFFFAOYSA-N	536575	US11242361, Compound 182	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536575&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078608	464921708							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137439	CC(=O)NCc1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2c1)-c1ccc(cc1)C#N	InChI=1S/C26H28N4O2/c1-18-26(25(32)17-29-12-4-3-5-13-29)23-14-21(16-28-19(2)31)8-11-24(23)30(18)22-9-6-20(15-27)7-10-22/h6-11,14H,3-5,12-13,16-17H2,1-2H3,(H,28,31)	MPDMVRSMBVJVAA-UHFFFAOYSA-N	536576	N-((1-(4-Cyanophenyl)-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-indol-5-yl)methyl)acetamide ::US11242361, Compound 183	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536576&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078539	464921709							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137440	Cc1c(C(=O)CN2CCCCC2)c2ncc(C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H24N4O/c1-16-12-20-23(25-14-16)22(21(28)15-26-10-4-3-5-11-26)17(2)27(20)19-8-6-18(13-24)7-9-19/h6-9,12,14H,3-5,10-11,15H2,1-2H3	VQFRNUSFWKKADR-UHFFFAOYSA-N	536577	4-(2,6-Dimethyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 184	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536577&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078521	464921710							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137441	Cc1c(C(=O)CN2CCCCC2)c2ccc(CN)cc2n1-c1ccc(Cl)cc1	InChI=1S/C23H26ClN3O/c1-16-23(22(28)15-26-11-3-2-4-12-26)20-10-5-17(14-25)13-21(20)27(16)19-8-6-18(24)7-9-19/h5-10,13H,2-4,11-12,14-15,25H2,1H3	VIUBVZWWGDMPBH-UHFFFAOYSA-N	536578	US11242361, Compound 185	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536578&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078639	464921711							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137442	Cc1c(C(=O)CN2CCCCC2)c2cc(N)ccc2n1-c1ccc(cc1)C#N	InChI=1S/C23H24N4O/c1-16-23(22(28)15-26-11-3-2-4-12-26)20-13-18(25)7-10-21(20)27(16)19-8-5-17(14-24)6-9-19/h5-10,13H,2-4,11-12,15,25H2,1H3	SJJRTKKVKMCMDP-UHFFFAOYSA-N	536579	4-(5-Amino-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-indol-1-yl)benzonitrile ::US11242361, Compound 186	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536579&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078510	464921712							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137443	Cc1c(C(=O)CN2CCCCC2)c2cc(NC(=O)C(C)(C)C)ccc2n1-c1ccc(cc1)C#N	InChI=1S/C28H32N4O2/c1-19-26(25(33)18-31-14-6-5-7-15-31)23-16-21(30-27(34)28(2,3)4)10-13-24(23)32(19)22-11-8-20(17-29)9-12-22/h8-13,16H,5-7,14-15,18H2,1-4H3,(H,30,34)	HVTNACJAGYNWDD-UHFFFAOYSA-N	536580	US11242361, Compound 187	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536580&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085834	464921713							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137444	CN(C)Cc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C25H30ClN3O/c1-18-25(24(30)17-28-13-5-4-6-14-28)22-12-7-19(16-27(2)3)15-23(22)29(18)21-10-8-20(26)9-11-21/h7-12,15H,4-6,13-14,16-17H2,1-3H3	MBRZSGOWLIGPDD-UHFFFAOYSA-N	536581	US11242361, Compound 188	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536581&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085958	464921714							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137445	Cc1c(C(=O)CN2CCCC(F)C2)c2ncc(C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23FN4O/c1-15-10-20-23(26-12-15)22(21(29)14-27-9-3-4-18(24)13-27)16(2)28(20)19-7-5-17(11-25)6-8-19/h5-8,10,12,18H,3-4,9,13-14H2,1-2H3	GDKCFSYXQZDRDQ-UHFFFAOYSA-N	536582	US11242361, Compound 189	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536582&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085857	464921715							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137446	Cc1c(C(=O)CN2CCC(F)CC2)c2ncc(C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23FN4O/c1-15-11-20-23(26-13-15)22(21(29)14-27-9-7-18(24)8-10-27)16(2)28(20)19-5-3-17(12-25)4-6-19/h3-6,11,13,18H,7-10,14H2,1-2H3	UUVDAMJROCGEEL-UHFFFAOYSA-N	536583	US11242361, Compound 190	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536583&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085853	464921716							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137447	CC(=O)Nc1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2c1)-c1ccc(cc1)C#N	InChI=1S/C25H26N4O2/c1-17-25(24(31)16-28-12-4-3-5-13-28)22-14-20(27-18(2)30)8-11-23(22)29(17)21-9-6-19(15-26)7-10-21/h6-11,14H,3-5,12-13,16H2,1-2H3,(H,27,30)	PEZXMGHPWWDJJS-UHFFFAOYSA-N	536584	US11242361, Compound 191	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536584&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078494	464921717							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137448	CN(C)c1c(C(=O)CN2CCCCC2)c2ccccc2n1-c1ccc(Cl)cc1	InChI=1S/C23H26ClN3O/c1-25(2)23-22(21(28)16-26-14-6-3-7-15-26)19-8-4-5-9-20(19)27(23)18-12-10-17(24)11-13-18/h4-5,8-13H,3,6-7,14-16H2,1-2H3	JFLIGLZKNCZYAV-UHFFFAOYSA-N	536585	US11242361, Compound 192	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536585&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085860	464921718							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137449	COc1cc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2cc1OC(F)(F)F	InChI=1S/C25H24F3N3O3/c1-16-24(21(32)15-30-10-4-3-5-11-30)19-12-22(33-2)23(34-25(26,27)28)13-20(19)31(16)18-8-6-17(14-29)7-9-18/h6-9,12-13H,3-5,10-11,15H2,1-2H3	KGUDNCQQQJBMRI-UHFFFAOYSA-N	536586	US11242361, Compound 193	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536586&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085854	464921719							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137450	Cc1c(C(=O)CN2CCCCC2)c2ccc(CCC(N)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C26H28N4O2/c1-18-26(24(31)17-29-13-3-2-4-14-29)22-11-7-19(8-12-25(28)32)15-23(22)30(18)21-9-5-20(16-27)6-10-21/h5-7,9-11,15H,2-4,8,12-14,17H2,1H3,(H2,28,32)	PQTHEIPVFVDTEQ-UHFFFAOYSA-N	536587	US11242361, Compound 194	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536587&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078533	464921720							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137451	Cc1c(C(=O)CN2CCCCC2)c2nc(C)c(C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C24H26N4O/c1-16-13-21-24(26-17(16)2)23(22(29)15-27-11-5-4-6-12-27)18(3)28(21)20-9-7-19(14-25)8-10-20/h7-10,13H,4-6,11-12,15H2,1-3H3	JGAFZMVWLTWJLG-UHFFFAOYSA-N	536588	US11242361, Compound 195	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536588&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085813	464921721							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137452	CN(C(C)=O)c1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2n1)-c1ccc(cc1)C#N	InChI=1S/C25H27N5O2/c1-17-24(22(32)16-29-13-5-4-6-14-29)25-21(11-12-23(27-25)28(3)18(2)31)30(17)20-9-7-19(15-26)8-10-20/h7-12H,4-6,13-14,16H2,1-3H3	PSXIJYNBXZHDHA-UHFFFAOYSA-N	536589	US11242361, Compound 196	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536589&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			155162030	464921722							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137453	CCOC(=O)Cc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C27H29N3O3/c1-3-33-26(32)16-21-9-12-23-24(15-21)30(22-10-7-20(17-28)8-11-22)19(2)27(23)25(31)18-29-13-5-4-6-14-29/h7-12,15H,3-6,13-14,16,18H2,1-2H3	JXZHUFGQVCZFHH-UHFFFAOYSA-N	536590	US11242361, Compound 197	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536590&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085798	464921723							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137454	Cc1c(C(=O)CN2CCCCC2)c2ccc(CC(O)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C25H25N3O3/c1-17-25(23(29)16-27-11-3-2-4-12-27)21-10-7-19(14-24(30)31)13-22(21)28(17)20-8-5-18(15-26)6-9-20/h5-10,13H,2-4,11-12,14,16H2,1H3,(H,30,31)	JIYUFYOGXJOYMK-UHFFFAOYSA-N	536591	US11242361, Compound 198	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536591&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085797	464921724							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137455	CNc1ccc2n(c(C)c(C(=O)CN3CCCCC3)c2c1)-c1ccc(cc1)C#N	InChI=1S/C24H26N4O/c1-17-24(23(29)16-27-12-4-3-5-13-27)21-14-19(26-2)8-11-22(21)28(17)20-9-6-18(15-25)7-10-20/h6-11,14,26H,3-5,12-13,16H2,1-2H3	YQWAQASUQUYQMY-UHFFFAOYSA-N	536592	US11242361, Compound 199	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536592&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078540	464921725							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137456	CCOC(=O)CCc1cc2n(c(C)c(C(=O)CN3CCCCC3)c2cc1C)-c1ccc(cc1)C#N	InChI=1S/C29H33N3O3/c1-4-35-28(34)13-10-23-17-26-25(16-20(23)2)29(27(33)19-31-14-6-5-7-15-31)21(3)32(26)24-11-8-22(18-30)9-12-24/h8-9,11-12,16-17H,4-7,10,13-15,19H2,1-3H3	VZXMMDYUWPBRCR-UHFFFAOYSA-N	536593	US11242361, Compound 200	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536593&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			155162088	464921726							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137457	Cc1c(C(=O)CN2CCCCC2)c2ccc(CCC(O)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C26H27N3O3/c1-18-26(24(30)17-28-13-3-2-4-14-28)22-11-7-19(8-12-25(31)32)15-23(22)29(18)21-9-5-20(16-27)6-10-21/h5-7,9-11,15H,2-4,8,12-14,17H2,1H3,(H,31,32)	RTYNUPJVCTXGHC-UHFFFAOYSA-N	536594	US11242361, Compound 201	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536594&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078571	464921727							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137458	Cc1c(C(=O)CN2CCCCC2)c2nc(C)c(CCC(O)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C26H28N4O3/c1-17-20(8-11-24(32)33)14-22-26(28-17)25(23(31)16-29-12-4-3-5-13-29)18(2)30(22)21-9-6-19(15-27)7-10-21/h6-7,9-10,14H,3-5,8,11-13,16H2,1-2H3,(H,32,33)	ZURVNDGBOXNESI-UHFFFAOYSA-N	536595	US11242361, Compound 202	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536595&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078600	464921728							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137459	Cc1c(C(=O)CN2CCCCC2)c2ccc(CC(N)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C25H26N4O2/c1-17-25(23(30)16-28-11-3-2-4-12-28)21-10-7-19(14-24(27)31)13-22(21)29(17)20-8-5-18(15-26)6-9-20/h5-10,13H,2-4,11-12,14,16H2,1H3,(H2,27,31)	ITSXXJCVWWBCQD-UHFFFAOYSA-N	536596	US11242361, Compound 203	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536596&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078662	464921729							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137460	CCN(CC)C(=O)CCc1cc2n(c(C)c(C(=O)CN3CCCCC3)c2nc1C)-c1ccc(cc1)C#N	InChI=1S/C30H37N5O2/c1-5-34(6-2)28(37)15-12-24-18-26-30(32-21(24)3)29(27(36)20-33-16-8-7-9-17-33)22(4)35(26)25-13-10-23(19-31)11-14-25/h10-11,13-14,18H,5-9,12,15-17,20H2,1-4H3	OQCRJXNAMVBFGP-UHFFFAOYSA-N	536597	US11242361, Compound 204	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536597&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078605	464921730							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137461	CC(=O)OCCc1ccc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C27H29N3O3/c1-19-27(26(32)18-29-13-4-3-5-14-29)24-11-8-21(12-15-33-20(2)31)16-25(24)30(19)23-9-6-22(17-28)7-10-23/h6-11,16H,3-5,12-15,18H2,1-2H3	YZPZMARWUHNUNJ-UHFFFAOYSA-N	536598	US11242361, Compound 205	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536598&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078603	464921731							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137462	Cc1c(C(=O)CN2CCCCC2)c2ccc(C=C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C25H25N3O/c1-3-19-9-12-22-23(15-19)28(21-10-7-20(16-26)8-11-21)18(2)25(22)24(29)17-27-13-5-4-6-14-27/h3,7-12,15H,1,4-6,13-14,17H2,2H3	YCLZFKCTESRADM-UHFFFAOYSA-N	536599	US11242361, Compound 206	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536599&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078549	464921732							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137463	Cc1c(C(=O)CN2CCCCC2)c2ccc(CCO)cc2n1-c1ccc(cc1)C#N	InChI=1S/C25H27N3O2/c1-18-25(24(30)17-27-12-3-2-4-13-27)22-10-7-19(11-14-29)15-23(22)28(18)21-8-5-20(16-26)6-9-21/h5-10,15,29H,2-4,11-14,17H2,1H3	CVWHZDDJJFUZSW-UHFFFAOYSA-N	536600	US11242361, Compound 207	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536600&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078513	464921733							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137464	Cc1c(C(=O)CN2CCCCC2)c2nc(ccc2n1-c1ccc(cc1)C#N)-n1nccn1	InChI=1S/C24H23N7O/c1-17-23(21(32)16-29-13-3-2-4-14-29)24-20(9-10-22(28-24)31-26-11-12-27-31)30(17)19-7-5-18(15-25)6-8-19/h5-12H,2-4,13-14,16H2,1H3	SCGXSKBLFDKYGS-UHFFFAOYSA-N	536601	US11242361, Compound 208	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536601&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078481	464921734							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137465	Cc1c(C(=O)CN2CCCCC2)c2nc(ccc2n1-c1ccc(cc1)C#N)-n1ccnn1	InChI=1S/C24H23N7O/c1-17-23(21(32)16-29-12-3-2-4-13-29)24-20(9-10-22(27-24)30-14-11-26-28-30)31(17)19-7-5-18(15-25)6-8-19/h5-11,14H,2-4,12-13,16H2,1H3	QTNOUQUJKWQEIX-UHFFFAOYSA-N	536602	US11242361, Compound 209	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536602&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078515	464921735							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137466	Cc1c(C(=O)CN2CCCCC2)c2nc(C)c(CCC(N)=O)cc2n1-c1ccc(cc1)C#N	InChI=1S/C26H29N5O2/c1-17-20(8-11-24(28)33)14-22-26(29-17)25(23(32)16-30-12-4-3-5-13-30)18(2)31(22)21-9-6-19(15-27)7-10-21/h6-7,9-10,14H,3-5,8,11-13,16H2,1-2H3,(H2,28,33)	SRGUQUWCNBTVDC-UHFFFAOYSA-N	536603	US11242361, Compound 210	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536603&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078625	464921736							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137467	COC(CNC(=O)CCc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1)OC	InChI=1S/C29H35N5O4/c1-20-28(25(35)19-33-13-5-4-6-14-33)29-24(34(20)23-10-7-21(16-30)8-11-23)15-22(17-32-29)9-12-26(36)31-18-27(37-2)38-3/h7-8,10-11,15,17,27H,4-6,9,12-14,18-19H2,1-3H3,(H,31,36)	DXWBHGFIZOKYDM-UHFFFAOYSA-N	536604	US11242361, Compound 296	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536604&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085770	464921737							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137468	Cc1c(C(=O)CN2CCCCC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O/c1-15-21(20(28)14-26-9-3-2-4-10-26)22-19(11-17(23)13-25-22)27(15)18-7-5-16(12-24)6-8-18/h5-8,11,13H,2-4,9-10,14H2,1H3	SMAMDKXPFTWUMK-UHFFFAOYSA-N	536605	4-(6-Bromo-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 297::US11242361, Compound 320	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536605&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085779	464921738							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137469	Cc1c(C(=O)CN2CCCCC2)c2ncc(CC(=O)N3CCCC3)cc2n1-c1ccc(cc1)C#N	InChI=1S/C28H31N5O2/c1-20-27(25(34)19-31-11-3-2-4-12-31)28-24(33(20)23-9-7-21(17-29)8-10-23)15-22(18-30-28)16-26(35)32-13-5-6-14-32/h7-10,15,18H,2-6,11-14,16,19H2,1H3	PGJYCMGNQFQWFK-UHFFFAOYSA-N	536606	US11242361, Compound 298	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536606&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078575	464921739							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137470	Cc1c(C(=O)CN2CCCCC2)c2ncc(CCC(=O)NCCCN=[N+]=[N-])cc2n1-c1ccc(cc1)C#N	InChI=1S/C28H32N8O2/c1-20-27(25(37)19-35-14-3-2-4-15-35)28-24(36(20)23-9-6-21(17-29)7-10-23)16-22(18-32-28)8-11-26(38)31-12-5-13-33-34-30/h6-7,9-10,16,18H,2-5,8,11-15,19H2,1H3,(H,31,38)	MJOBLGANBMNFRX-UHFFFAOYSA-N	536607	US11242361, Compound 299	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536607&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085836	464921740							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137471	Cc1c(C(=O)CN2CCCCC2)c2ncc(cc2n1-c1ccc(cc1)C#N)C(F)(F)F	InChI=1S/C23H21F3N4O/c1-15-21(20(31)14-29-9-3-2-4-10-29)22-19(11-17(13-28-22)23(24,25)26)30(15)18-7-5-16(12-27)6-8-18/h5-8,11,13H,2-4,9-10,14H2,1H3	HFWRAYLPKDEKGY-UHFFFAOYSA-N	536608	US11242361, Compound 300	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536608&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085837	464921741							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137472	Cc1c(C(=O)CN2CCCCC2)c2ncc(cc2n1-c1ccc(cc1)C#N)C(F)F	InChI=1S/C23H22F2N4O/c1-15-21(20(30)14-28-9-3-2-4-10-28)22-19(11-17(13-27-22)23(24)25)29(15)18-7-5-16(12-26)6-8-18/h5-8,11,13,23H,2-4,9-10,14H2,1H3	BDNJVVLASXWEKW-UHFFFAOYSA-N	536609	US11242361, Compound 301	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536609&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078611	464921742							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137473	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(cc2n1-c1ccc(cc1)C#N)C(F)(F)F	InChI=1S/C23H21F3N4O2/c1-14-21(20(32)13-29-8-6-18(31)7-9-29)22-19(10-16(12-28-22)23(24,25)26)30(14)17-4-2-15(11-27)3-5-17/h2-5,10,12,18,31H,6-9,13H2,1H3	PPLCDSQMLZZGJH-UHFFFAOYSA-N	536610	US11242361, Compound 302	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536610&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085835	464921743							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137474	CCN(CCc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1)S(C)(=O)=O	InChI=1S/C27H33N5O3S/c1-4-31(36(3,34)35)15-12-22-16-24-27(29-18-22)26(25(33)19-30-13-6-5-7-14-30)20(2)32(24)23-10-8-21(17-28)9-11-23/h8-11,16,18H,4-7,12-15,19H2,1-3H3	DSJFOAAWNASXHL-UHFFFAOYSA-N	536611	US11242361, Compound 303	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536611&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085980	464921744							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137475	Cc1c(C(=O)CN2CCCCC2)c2ncc(CCC(=O)NCCN=[N+]=[N-])cc2n1-c1ccc(cc1)C#N	InChI=1S/C27H30N8O2/c1-19-26(24(36)18-34-13-3-2-4-14-34)27-23(35(19)22-8-5-20(16-28)6-9-22)15-21(17-31-27)7-10-25(37)30-11-12-32-33-29/h5-6,8-9,15,17H,2-4,7,10-14,18H2,1H3,(H,30,37)	BDTFPYZSRVCYAI-UHFFFAOYSA-N	536612	US11242361, Compound 304	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536612&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085981	464921745							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137476	CCCNC(=O)\C=C\c1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C28H31N5O2/c1-3-13-30-26(35)12-9-22-16-24-28(31-18-22)27(25(34)19-32-14-5-4-6-15-32)20(2)33(24)23-10-7-21(17-29)8-11-23/h7-12,16,18H,3-6,13-15,19H2,1-2H3,(H,30,35)/b12-9+	QLSNRYIRVHTRDF-FMIVXFBMSA-N	536613	US11242361, Compound 305	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536613&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085979	464921746							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137477	C[C@@H]1CCCN1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C22H21BrN4O/c1-14-4-3-9-26(14)13-20(28)21-15(2)27(18-7-5-16(11-24)6-8-18)19-10-17(23)12-25-22(19)21/h5-8,10,12,14H,3-4,9,13H2,1-2H3/t14-/m1/s1	FBDDWEWUCQNQSZ-CQSZACIVSA-N	536614	US11242361, Compound 306	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536614&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085983	464921747							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137478	C[C@H]1CCCN1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C22H21BrN4O/c1-14-4-3-9-26(14)13-20(28)21-15(2)27(18-7-5-16(11-24)6-8-18)19-10-17(23)12-25-22(19)21/h5-8,10,12,14H,3-4,9,13H2,1-2H3/t14-/m0/s1	FBDDWEWUCQNQSZ-AWEZNQCLSA-N	536615	US11242361, Compound 307	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536615&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085986	464921748							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137479	C[C@H]1CCCCN1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C23H23BrN4O/c1-15-5-3-4-10-27(15)14-21(29)22-16(2)28(19-8-6-17(12-25)7-9-19)20-11-18(24)13-26-23(20)22/h6-9,11,13,15H,3-5,10,14H2,1-2H3/t15-/m0/s1	XPLXIOUJXDIWGD-HNNXBMFYSA-N	536616	US11242361, Compound 308	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536616&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085987	464921749							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137480	C[C@@H]1CCCCN1CC(=O)c1c(C)n(-c2ccc(cc2)C#N)c2cc(Br)cnc12	InChI=1S/C23H23BrN4O/c1-15-5-3-4-10-27(15)14-21(29)22-16(2)28(19-8-6-17(12-25)7-9-19)20-11-18(24)13-26-23(20)22/h6-9,11,13,15H,3-5,10,14H2,1-2H3/t15-/m1/s1	XPLXIOUJXDIWGD-OAHLLOKOSA-N	536617	US11242361, Compound 309	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536617&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086082	464921750							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137481	Cc1c(C(=O)CN2CCCC2(C)C)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23BrN4O/c1-15-21(20(29)14-27-10-4-9-23(27,2)3)22-19(11-17(24)13-26-22)28(15)18-7-5-16(12-25)6-8-18/h5-8,11,13H,4,9-10,14H2,1-3H3	YBPMQUIRCGKMQJ-UHFFFAOYSA-N	536618	US11242361, Compound 310	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536618&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086083	464921751							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137482	Cc1c(C(=O)CN2CCC(CO)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23BrN4O2/c1-15-22(21(30)13-27-8-6-17(14-29)7-9-27)23-20(10-18(24)12-26-23)28(15)19-4-2-16(11-25)3-5-19/h2-5,10,12,17,29H,6-9,13-14H2,1H3	BMXAWBPJQCMBLP-UHFFFAOYSA-N	536619	US11242361, Compound 311::US11242361, Compound 312	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536619&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085943	464921752							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137483	Cc1c(C(=O)CN2CCC(CO)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23BrN4O2/c1-15-22(21(30)13-27-8-6-17(14-29)7-9-27)23-20(10-18(24)12-26-23)28(15)19-4-2-16(11-25)3-5-19/h2-5,10,12,17,29H,6-9,13-14H2,1H3	BMXAWBPJQCMBLP-UHFFFAOYSA-N	536619	US11242361, Compound 311::US11242361, Compound 312	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536619&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085943	464921752							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137484	Cc1c(C(=O)CN2CCC=CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H19BrN4O/c1-15-21(20(28)14-26-9-3-2-4-10-26)22-19(11-17(23)13-25-22)27(15)18-7-5-16(12-24)6-8-18/h2-3,5-8,11,13H,4,9-10,14H2,1H3	ACPTYAGIALXTCF-UHFFFAOYSA-N	536621	US11242361, Compound 314	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536621&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085940	464921753							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137485	Cc1c(C(=O)CN2CC=CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H17BrN4O/c1-14-20(19(27)13-25-8-2-3-9-25)21-18(10-16(22)12-24-21)26(14)17-6-4-15(11-23)5-7-17/h2-7,10,12H,8-9,13H2,1H3	KGMRADLKJGIGFE-UHFFFAOYSA-N	536622	US11242361, Compound 315	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536622&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085937	464921754							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137486	Cc1c(C(=O)CN2CCCCC2(C)C)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C24H25BrN4O/c1-16-22(21(30)15-28-11-5-4-10-24(28,2)3)23-20(12-18(25)14-27-23)29(16)19-8-6-17(13-26)7-9-19/h6-9,12,14H,4-5,10-11,15H2,1-3H3	XUDCCONCHMIJTC-UHFFFAOYSA-N	536623	US11242361, Compound 318	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536623&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085863	464921755							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137487	CN(C)C(=O)OCC#Cc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C28H29N5O3/c1-20-26(25(34)19-32-13-5-4-6-14-32)27-24(33(20)23-11-9-21(17-29)10-12-23)16-22(18-30-27)8-7-15-36-28(35)31(2)3/h9-12,16,18H,4-6,13-15,19H2,1-3H3	MLALXBSMELBLGP-UHFFFAOYSA-N	536624	US11242361, Compound 319	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536624&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078580	464921756							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137488	Cc1c(C(=O)CN2CCCCC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O/c1-15-21(20(28)14-26-9-3-2-4-10-26)22-19(11-17(23)13-25-22)27(15)18-7-5-16(12-24)6-8-18/h5-8,11,13H,2-4,9-10,14H2,1H3	SMAMDKXPFTWUMK-UHFFFAOYSA-N	536605	4-(6-Bromo-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 297::US11242361, Compound 320	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536605&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085779	464921738							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137489	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(\C=C\c3nnc(o3)C(F)(F)F)cc2n1-c1ccc(cc1)C#N	InChI=1S/C27H23F3N6O3/c1-16-24(22(38)15-35-10-8-20(37)9-11-35)25-21(36(16)19-5-2-17(13-31)3-6-19)12-18(14-32-25)4-7-23-33-34-26(39-23)27(28,29)30/h2-7,12,14,20,37H,8-11,15H2,1H3/b7-4+	BADKUYWNRYPRGU-QPJJXVBHSA-N	536626	US11242361, Compound 321	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536626&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085865	464921757							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137490	Cc1c(C(=O)CN2CCC(F)(F)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H17BrF2N4O/c1-13-19(18(29)11-27-7-6-21(23,24)12-27)20-17(8-15(22)10-26-20)28(13)16-4-2-14(9-25)3-5-16/h2-5,8,10H,6-7,11-12H2,1H3	BLOGHQWMYLWTBV-UHFFFAOYSA-N	536627	US11242361, Compound 324	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536627&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085985	464921758							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137491	Cc1c(C(=O)CN2CCC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C20H17BrN4O/c1-13-19(18(26)12-24-7-2-8-24)20-17(9-15(21)11-23-20)25(13)16-5-3-14(10-22)4-6-16/h3-6,9,11H,2,7-8,12H2,1H3	UHGFMSLONYGRKE-UHFFFAOYSA-N	536628	US11242361, Compound 325	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536628&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085984	464921759							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137492	COc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C23H24N4O2/c1-16-22(21(28)15-26-10-4-3-5-11-26)23-20(12-19(29-2)14-25-23)27(16)18-8-6-17(13-24)7-9-18/h6-9,12,14H,3-5,10-11,15H2,1-2H3	ODLBQQUCFVDONT-UHFFFAOYSA-N	536629	4-(6-Methoxy-2-methyl-3-(2-(piperidin-1-yl)acetyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)benzonitrile ::US11242361, Compound 326	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536629&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078681	464921760							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137493	Cc1c(C(=O)CN2CCS(=O)(=O)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H19BrN4O3S/c1-14-20(19(27)13-25-6-8-30(28,29)9-7-25)21-18(10-16(22)12-24-21)26(14)17-4-2-15(11-23)3-5-17/h2-5,10,12H,6-9,13H2,1H3	QZCAAGFBMMHSBA-UHFFFAOYSA-N	536630	US11242361, Compound 327	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536630&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086087	464921761							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137494	Cc1c(C(=O)CN2CC[C@H](O)[C@@H](O)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O3/c1-13-21(20(30)12-26-7-6-18(28)19(29)11-26)22-17(8-15(23)10-25-22)27(13)16-4-2-14(9-24)3-5-16/h2-5,8,10,18-19,28-29H,6-7,11-12H2,1H3/t18-,19-/m0/s1	HVZDHJOKOLPEQT-OALUTQOASA-N	536631	US11242361, Compound 328	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536631&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085915	464921762							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137495	Cc1c(C(=O)CN2CCOCC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H19BrN4O2/c1-14-20(19(27)13-25-6-8-28-9-7-25)21-18(10-16(22)12-24-21)26(14)17-4-2-15(11-23)3-5-17/h2-5,10,12H,6-9,13H2,1H3	SNJVCLZPMSWQDM-UHFFFAOYSA-N	536632	US11242361, Compound 329	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536632&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085917	464921763							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137496	CN1CCN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)CC1	InChI=1S/C22H22BrN5O/c1-15-21(20(29)14-27-9-7-26(2)8-10-27)22-19(11-17(23)13-25-22)28(15)18-5-3-16(12-24)4-6-18/h3-6,11,13H,7-10,14H2,1-2H3	IJMOEUSNAZVFLU-UHFFFAOYSA-N	536633	US11242361, Compound 330	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536633&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			140919684	464921764							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137497	Cc1c(C(=O)CN2CCSCC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H19BrN4OS/c1-14-20(19(27)13-25-6-8-28-9-7-25)21-18(10-16(22)12-24-21)26(14)17-4-2-15(11-23)3-5-17/h2-5,10,12H,6-9,13H2,1H3	NPJOXRMHMTYLFR-UHFFFAOYSA-N	536634	US11242361, Compound 331	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536634&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085916	464921765							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137498	Cc1c(C(=O)CN2CC[C@H](O)[C@H](O)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O3/c1-13-21(20(30)12-26-7-6-18(28)19(29)11-26)22-17(8-15(23)10-25-22)27(13)16-4-2-14(9-24)3-5-16/h2-5,8,10,18-19,28-29H,6-7,11-12H2,1H3/t18-,19+/m0/s1	HVZDHJOKOLPEQT-RBUKOAKNSA-N	536635	US11242361, Compound 332::US11242361, Compound 356	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536635&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085814	464921766							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137499	Cc1c(C(=O)CN2CCC(O)CC2)c2ncccc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O2/c1-15-21(20(28)14-25-11-8-18(27)9-12-25)22-19(3-2-10-24-22)26(15)17-6-4-16(13-23)5-7-17/h2-7,10,18,27H,8-9,11-12,14H2,1H3	CINPDBATMRGOOJ-UHFFFAOYSA-N	536636	US11242361, Compound 335	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536636&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085867	464921767							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137500	CC(C)c1c(C(=O)CN2CCCCC2)c2ncccc2n1-c1ccc(cc1)C#N	InChI=1S/C24H26N4O/c1-17(2)24-22(21(29)16-27-13-4-3-5-14-27)23-20(7-6-12-26-23)28(24)19-10-8-18(15-25)9-11-19/h6-12,17H,3-5,13-14,16H2,1-2H3	SQTJLSZXJWNMFR-UHFFFAOYSA-N	536637	US11242361, Compound 336	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536637&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085868	464921768							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137501	Cc1c(C(=O)CN2CCC(O)CC2)c2ccccc2n1-c1ccc(cc1)C#N	InChI=1S/C23H23N3O2/c1-16-23(22(28)15-25-12-10-19(27)11-13-25)20-4-2-3-5-21(20)26(16)18-8-6-17(14-24)7-9-18/h2-9,19,27H,10-13,15H2,1H3	NJBFIFFYHNAFNW-UHFFFAOYSA-N	536638	US11242361, Compound 337	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536638&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085869	464921769							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137502	C[C@H]1C[C@@H](C)CN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)C1	InChI=1S/C24H25BrN4O/c1-15-8-16(2)13-28(12-15)14-22(30)23-17(3)29(20-6-4-18(10-26)5-7-20)21-9-19(25)11-27-24(21)23/h4-7,9,11,15-16H,8,12-14H2,1-3H3/t15-,16+	YZLSEJCLDRTNRJ-IYBDPMFKSA-N	536639	US11242361, Compound 338	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536639&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085768	464921770							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137503	COc1cnc2c(C(=O)CN3CCC(O)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C23H24N4O3/c1-15-22(21(29)14-26-9-7-18(28)8-10-26)23-20(11-19(30-2)13-25-23)27(15)17-5-3-16(12-24)4-6-17/h3-6,11,13,18,28H,7-10,14H2,1-2H3	SCVNRKRTONICRS-UHFFFAOYSA-N	536640	US11242361, Compound 339	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536640&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085776	464921771							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137504	CCOc1cnc2c(C(=O)CN3CCC(O)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C24H26N4O3/c1-3-31-20-12-21-24(26-14-20)23(22(30)15-27-10-8-19(29)9-11-27)16(2)28(21)18-6-4-17(13-25)5-7-18/h4-7,12,14,19,29H,3,8-11,15H2,1-2H3	SBTAHVNUWVAKJD-UHFFFAOYSA-N	536641	US11242361, Compound 340	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536641&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085780	464921772							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137505	COCCOc1cnc2c(C(=O)CN3CCC(O)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C25H28N4O4/c1-17-24(23(31)16-28-9-7-20(30)8-10-28)25-22(13-21(15-27-25)33-12-11-32-2)29(17)19-5-3-18(14-26)4-6-19/h3-6,13,15,20,30H,7-12,16H2,1-2H3	DWGRZVHNSHTHQI-UHFFFAOYSA-N	536642	US11242361, Compound 341	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536642&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085786	464921773							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137506	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(CCNS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C24H29ClN4O4S/c1-16-23(22(31)15-28-11-8-20(30)9-12-28)24-21(29(16)19-5-3-18(25)4-6-19)13-17(14-26-24)7-10-27-34(2,32)33/h3-6,13-14,20,27,30H,7-12,15H2,1-2H3	APLRIAOSUYIKNO-UHFFFAOYSA-N	536643	US11242361, Compound 342	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536643&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078550	464921774							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137507	Cc1c(C(=O)CN2CC3(COC3)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H19BrN4O2/c1-14-20(19(28)9-26-10-22(11-26)12-29-13-22)21-18(6-16(23)8-25-21)27(14)17-4-2-15(7-24)3-5-17/h2-6,8H,9-13H2,1H3	RLPJGYZHTFCHPT-UHFFFAOYSA-N	536644	US11242361, Compound 343	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536644&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085941	464921775							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137508	Cc1c(C(=O)CN2CCNC(=O)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H18BrN5O2/c1-13-20(18(28)11-26-7-6-24-19(29)12-26)21-17(8-15(22)10-25-21)27(13)16-4-2-14(9-23)3-5-16/h2-5,8,10H,6-7,11-12H2,1H3,(H,24,29)	GNLNUQWJBBFKIW-UHFFFAOYSA-N	536645	US11242361, Compound 344	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536645&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085945	464921776							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137509	Cc1c(C(=O)CN2CCCCO2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C21H19BrN4O2/c1-14-20(19(27)13-25-8-2-3-9-28-25)21-18(10-16(22)12-24-21)26(14)17-6-4-15(11-23)5-7-17/h4-7,10,12H,2-3,8-9,13H2,1H3	MCEGSFZBNMYZOP-UHFFFAOYSA-N	536646	US11242361, Compound 345	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536646&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085944	464921777							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137510	Cc1c(C(=O)CN2CCCCC2)c2ncc(CCN3CCCC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H33ClN4O/c1-20-26(25(33)19-31-14-3-2-4-15-31)27-24(32(20)23-9-7-22(28)8-10-23)17-21(18-29-27)11-16-30-12-5-6-13-30/h7-10,17-18H,2-6,11-16,19H2,1H3	VOKJTBXHQOKYRW-UHFFFAOYSA-N	536647	US11242361, Compound 346	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536647&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078519	464921778							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137511	CCCOc1cnc2c(C(=O)CN3CCC(O)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C25H28N4O3/c1-3-12-32-21-13-22-25(27-15-21)24(23(31)16-28-10-8-20(30)9-11-28)17(2)29(22)19-6-4-18(14-26)5-7-19/h4-7,13,15,20,30H,3,8-12,16H2,1-2H3	ZOKKTDUTPHMXFC-UHFFFAOYSA-N	536648	US11242361, Compound 347	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536648&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085929	464921779							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137512	C[C@@H]1C[C@@H](C)CN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)C1	InChI=1S/C24H25BrN4O/c1-15-8-16(2)13-28(12-15)14-22(30)23-17(3)29(20-6-4-18(10-26)5-7-20)21-9-19(25)11-27-24(21)23/h4-7,9,11,15-16H,8,12-14H2,1-3H3/t15-,16-/m1/s1	YZLSEJCLDRTNRJ-HZPDHXFCSA-N	536649	US11242361, Compound 348	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536649&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085928	464921780							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137513	C[C@H]1C[C@H](C)CN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)C1	InChI=1S/C24H25BrN4O/c1-15-8-16(2)13-28(12-15)14-22(30)23-17(3)29(20-6-4-18(10-26)5-7-20)21-9-19(25)11-27-24(21)23/h4-7,9,11,15-16H,8,12-14H2,1-3H3/t15-,16-/m0/s1	YZLSEJCLDRTNRJ-HOTGVXAUSA-N	536650	US11242361, Compound 349	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536650&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085930	464921781							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137514	CCOC(=O)C[C@@H](C)c1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C28H32N4O3/c1-4-35-26(34)14-19(2)22-15-24-28(30-17-22)27(25(33)18-31-12-6-5-7-13-31)20(3)32(24)23-10-8-21(16-29)9-11-23/h8-11,15,17,19H,4-7,12-14,18H2,1-3H3/t19-/m1/s1	KWGPZNTUJLVYDO-LJQANCHMSA-N	536651	US11242361, Compound 350	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536651&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118086084	464921782							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137515	CCOC(=O)C[C@H](C)c1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C28H32N4O3/c1-4-35-26(34)14-19(2)22-15-24-28(30-17-22)27(25(33)18-31-12-6-5-7-13-31)20(3)32(24)23-10-8-21(16-29)9-11-23/h8-11,15,17,19H,4-7,12-14,18H2,1-3H3/t19-/m0/s1	KWGPZNTUJLVYDO-IBGZPJMESA-N	536652	US11242361, Compound 351	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536652&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085810	464921783							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137516	CN(C)CC1CCN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)CC1	InChI=1S/C25H28BrN5O/c1-17-24(23(32)16-30-10-8-19(9-11-30)15-29(2)3)25-22(12-20(26)14-28-25)31(17)21-6-4-18(13-27)5-7-21/h4-7,12,14,19H,8-11,15-16H2,1-3H3	MHUCLUSYFDBLOF-UHFFFAOYSA-N	536653	US11242361, Compound 352	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536653&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085820	464921784							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137517	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O2/c1-14-21(20(29)13-26-8-6-18(28)7-9-26)22-19(10-16(23)12-25-22)27(14)17-4-2-15(11-24)3-5-17/h2-5,10,12,18,28H,6-9,13H2,1H3	POBXYKCOJQZEJE-UHFFFAOYSA-N	536654	US11242361, Compound 353	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536654&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085815	464921785							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137518	Cc1c(C(=O)CN2CCC(CN)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H24BrN5O/c1-15-22(21(30)14-28-8-6-17(12-26)7-9-28)23-20(10-18(24)13-27-23)29(15)19-4-2-16(11-25)3-5-19/h2-5,10,13,17H,6-9,12,14,26H2,1H3	ITGWPDZNGGDORF-UHFFFAOYSA-N	536655	US11242361, Compound 354	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536655&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085822	464921786							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137519	Cc1c(C(=O)CN2CC[C@@H](O)[C@@H](O)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O3/c1-13-21(20(30)12-26-7-6-18(28)19(29)11-26)22-17(8-15(23)10-25-22)27(13)16-4-2-14(9-24)3-5-16/h2-5,8,10,18-19,28-29H,6-7,11-12H2,1H3/t18-,19+/m1/s1	HVZDHJOKOLPEQT-MOPGFXCFSA-N	536656	US11242361, Compound 355	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536656&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085816	464921787							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137520	Cc1c(C(=O)CN2CC[C@H](O)[C@H](O)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H21BrN4O3/c1-13-21(20(30)12-26-7-6-18(28)19(29)11-26)22-17(8-15(23)10-25-22)27(13)16-4-2-14(9-24)3-5-16/h2-5,8,10,18-19,28-29H,6-7,11-12H2,1H3/t18-,19+/m0/s1	HVZDHJOKOLPEQT-RBUKOAKNSA-N	536635	US11242361, Compound 332::US11242361, Compound 356	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536635&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085814	464921766							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137521	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(CCS(N)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C23H27ClN4O4S/c1-15-22(21(30)14-27-9-6-19(29)7-10-27)23-20(28(15)18-4-2-17(24)3-5-18)12-16(13-26-23)8-11-33(25,31)32/h2-5,12-13,19,29H,6-11,14H2,1H3,(H2,25,31,32)	WOWJUSUTCUDYDU-UHFFFAOYSA-N	536658	US11242361, Compound 357	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536658&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078506	464921788							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137522	Cc1c(C(=O)CN2CC3(CCC3)C2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C23H21BrN4O/c1-15-21(20(29)12-27-13-23(14-27)7-2-8-23)22-19(9-17(24)11-26-22)28(15)18-5-3-16(10-25)4-6-18/h3-6,9,11H,2,7-8,12-14H2,1H3	ZEVVEIKGHNJXKE-UHFFFAOYSA-N	536659	US11242361, Compound 359	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>10000							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536659&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085819	464921789							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137523	Cc1c(C(=O)CN2CCCCC2)c2ncc(CN3CCCC3)cc2n1-c1ccc(cc1)C#N	InChI=1S/C27H31N5O/c1-20-26(25(33)19-31-11-3-2-4-12-31)27-24(32(20)23-9-7-21(16-28)8-10-23)15-22(17-29-27)18-30-13-5-6-14-30/h7-10,15,17H,2-6,11-14,18-19H2,1H3	CELRIEJLNMRBDD-UHFFFAOYSA-N	536660	US11242361, Compound 360	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536660&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118078497	464921790							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137524	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(CCC(=O)NCCCC#C)cc2n1-c1ccc(cc1)C#N	InChI=1S/C30H33N5O3/c1-3-4-5-14-32-28(38)11-8-23-17-26-30(33-19-23)29(27(37)20-34-15-12-25(36)13-16-34)21(2)35(26)24-9-6-22(18-31)7-10-24/h1,6-7,9-10,17,19,25,36H,4-5,8,11-16,20H2,2H3,(H,32,38)	WFZMBLBDHITHLL-UHFFFAOYSA-N	536661	US11242361, Compound 361	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536661&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085821	464921791							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137525	Cc1c(C(=O)CN2CCC(O)CC2)c2ncc(CCC(=O)NCCCC#N)cc2n1-c1ccc(cc1)C#N	InChI=1S/C29H32N6O3/c1-20-28(26(37)19-34-14-10-24(36)11-15-34)29-25(35(20)23-7-4-21(17-31)5-8-23)16-22(18-33-29)6-9-27(38)32-13-3-2-12-30/h4-5,7-8,16,18,24,36H,2-3,6,9-11,13-15,19H2,1H3,(H,32,38)	ZKNPWGMLTYHDRR-UHFFFAOYSA-N	536662	US11242361, Compound 362	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536662&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085824	464921792							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137526	COCCOc1cnc2c(C(=O)CN3CCC(O)CC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C24H28ClN3O4/c1-16-23(22(30)15-27-9-7-19(29)8-10-27)24-21(13-20(14-26-24)32-12-11-31-2)28(16)18-5-3-17(25)4-6-18/h3-6,13-14,19,29H,7-12,15H2,1-2H3	ZFSULKNALMLDNY-UHFFFAOYSA-N	536663	US11242361, Compound 363	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536663&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			155162091	464921793							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137527	COCCOc1cnc2c(C(=O)CN3CCCCC3)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C24H28ClN3O3/c1-17-23(22(29)16-27-10-4-3-5-11-27)24-21(14-20(15-26-24)31-13-12-30-2)28(17)19-8-6-18(25)7-9-19/h6-9,14-15H,3-5,10-13,16H2,1-2H3	CAIVJNPUZDWKKB-UHFFFAOYSA-N	536664	US11242361, Compound 364	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536664&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085823	464921794							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137528	CCOC(=O)CC1CCN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)CC1	InChI=1S/C26H27BrN4O3/c1-3-34-24(33)12-18-8-10-30(11-9-18)16-23(32)25-17(2)31(21-6-4-19(14-28)5-7-21)22-13-20(27)15-29-26(22)25/h4-7,13,15,18H,3,8-12,16H2,1-2H3	MTSVKIHWJQDSQM-UHFFFAOYSA-N	536665	US11242361, Compound 365	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536665&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085825	464921795							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137529	CCOC(=O)CC1CCCN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)C1	InChI=1S/C26H27BrN4O3/c1-3-34-24(33)11-19-5-4-10-30(15-19)16-23(32)25-17(2)31(21-8-6-18(13-28)7-9-21)22-12-20(27)14-29-26(22)25/h6-9,12,14,19H,3-5,10-11,15-16H2,1-2H3	OKPFSAYWJLPHJG-UHFFFAOYSA-N	536666	US11242361, Compound 366	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536666&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085832	464921796							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137530	Cc1c(C(=O)CN2CCC(N)CC2)c2ncc(Br)cc2n1-c1ccc(cc1)C#N	InChI=1S/C22H22BrN5O/c1-14-21(20(29)13-27-8-6-17(25)7-9-27)22-19(10-16(23)12-26-22)28(14)18-4-2-15(11-24)3-5-18/h2-5,10,12,17H,6-9,13,25H2,1H3	HENHTFWOVYKVBY-UHFFFAOYSA-N	536667	US11242361, Compound 367	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536667&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085976	464921797							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137531	CCOC(=O)CNCC1CCN(CC(=O)c2c(C)n(-c3ccc(cc3)C#N)c3cc(Br)cnc23)CC1	InChI=1S/C27H30BrN5O3/c1-3-36-25(35)16-30-14-20-8-10-32(11-9-20)17-24(34)26-18(2)33(22-6-4-19(13-29)5-7-22)23-12-21(28)15-31-27(23)26/h4-7,12,15,20,30H,3,8-11,14,16-17H2,1-2H3	VFDRAUUXMDHCTH-UHFFFAOYSA-N	536668	US11242361, Compound 368	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 5500							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536668&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085975	464921798							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1137532	COc1cnc2c(C(=O)CN3CCC(CN)CC3)c(C)n(-c3ccc(cc3)C#N)c2c1	InChI=1S/C24H27N5O2/c1-16-23(22(30)15-28-9-7-18(13-26)8-10-28)24-21(11-20(31-2)14-27-24)29(16)19-5-3-17(12-25)4-6-19/h3-6,11,14,18H,7-10,13,15,26H2,1-2H3	KRHFYAUZBRGGAQ-UHFFFAOYSA-N	536669	US11242361, Compound 369	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 550							US Patent		10.7270/Q2TF01HP		aid1806336	US11242361	Cullen, M; Hauck, S; Geng, B; Foley, M; Bastos, CM; Munoz, B; Haeberlein, M; Tait, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=536669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=536669&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			118085972	464921799							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247405	Cc1cc(C(=O)CN2C3CC4CC2CC(O)(C4)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H27N3O2/c1-15-7-22(16(2)27(15)19-5-3-17(13-25)4-6-19)23(28)14-26-20-8-18-9-21(26)12-24(29,10-18)11-20/h3-7,18,20-21,29H,8-12,14H2,1-2H3	VIMSXPBLPZDCDL-UHFFFAOYSA-N	590300	US11560385, Compound 81B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590300&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274536	479268864							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247406	Cc1cc(C(=O)CN2C3C[C@@H](O)C2CCC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-10-19(15(2)25(14)17-8-6-16(12-23)7-9-17)22(27)13-24-18-4-3-5-20(24)21(26)11-18/h6-10,18,20-21,26H,3-5,11,13H2,1-2H3/t18?,20?,21-/m1/s1	SUURUZRJJDROIF-DQVLVPHSSA-N	590301	US11560385, Compound 82B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590301&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677914	479268865							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247407	Cc1cc(C(=O)CN2C3C[C@H](O)C2CCC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-10-19(15(2)25(14)17-8-6-16(12-23)7-9-17)22(27)13-24-18-4-3-5-20(24)21(26)11-18/h6-10,18,20-21,26H,3-5,11,13H2,1-2H3/t18?,20?,21-/m0/s1	SUURUZRJJDROIF-MNLRITNHSA-N	590302	US11560385, Compound 83B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590302&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677931	479268866							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247408	Cc1cc(C(=O)CN2C3CC4CC2CC(C3)O4)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H25N3O2/c1-14-7-22(15(2)26(14)17-5-3-16(12-24)4-6-17)23(27)13-25-18-8-20-10-19(25)11-21(9-18)28-20/h3-7,18-21H,8-11,13H2,1-2H3	ZSGCRCPTVFUUJK-UHFFFAOYSA-N	590303	US11560385, Compound 84B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590303&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274656	479268867							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247409	Cc1cc(C(=O)CN2C3CCCC2CC(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-10-22(16(2)26(15)18-8-6-17(13-24)7-9-18)23(28)14-25-19-4-3-5-20(25)12-21(27)11-19/h6-10,19-21,27H,3-5,11-12,14H2,1-2H3	QYVGTGOQBULAMC-UHFFFAOYSA-N	590304	US11560385, Compound 85B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590304&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290663	479268868							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247410	Cc1cc(C(=O)CN2C3CCCC2CC(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-10-22(16(2)26(15)18-8-6-17(13-24)7-9-18)23(28)14-25-19-4-3-5-20(25)12-21(27)11-19/h6-10,19-21,27H,3-5,11-12,14H2,1-2H3	QYVGTGOQBULAMC-UHFFFAOYSA-N	590305	US11560385, Compound 86B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590305&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290663	479268869							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247411	Cc1cc(C(=O)CN2C3CCCC2CCC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H27N3O/c1-16-13-22(17(2)26(16)21-11-9-18(14-24)10-12-21)23(27)15-25-19-5-3-6-20(25)8-4-7-19/h9-13,19-20H,3-8,15H2,1-2H3	CPRGKBGSXOCRKC-UHFFFAOYSA-N	590306	US11560385, Compound 87B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590306&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290566	479268870							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247412	COC1C[C@H]2CC[C@H](C1)N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-10-22(16(2)26(15)18-6-4-17(13-24)5-7-18)23(27)14-25-19-8-9-20(25)12-21(11-19)28-3/h4-7,10,19-21H,8-9,11-12,14H2,1-3H3/t19-,20-/m1/s1	LPVWYMJXTFQUFR-WOJBJXKFSA-N	590307	US11560385, Compound 88B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590307&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290571	479268871							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247413	COC1C[C@H]2CC[C@H](C1)N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-10-22(16(2)26(15)18-6-4-17(13-24)5-7-18)23(27)14-25-19-8-9-20(25)12-21(11-19)28-3/h4-7,10,19-21H,8-9,11-12,14H2,1-3H3/t19-,20-/m1/s1	LPVWYMJXTFQUFR-WOJBJXKFSA-N	590308	US11560385, Compound 89B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590308&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290571	479268872							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247414	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(C#N)c(F)c1	InChI=1S/C21H22FN3O2/c1-12-7-17(21(27)11-24-15-5-6-19(24)20(26)9-15)13(2)25(12)16-4-3-14(10-23)18(22)8-16/h3-4,7-8,15,19-20,26H,5-6,9,11H2,1-2H3/t15?,19?,20-/m0/s1	WWUYBXOVQHZECE-OAAAQFAESA-N	590309	US11560385, Compound 90B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590309&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290640	479268873							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247415	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1F)C#N	InChI=1S/C21H22FN3O2/c1-12-7-16(21(27)11-24-15-4-6-19(24)20(26)9-15)13(2)25(12)18-5-3-14(10-23)8-17(18)22/h3,5,7-8,15,19-20,26H,4,6,9,11H2,1-2H3/t15?,19?,20-/m0/s1	HDMGJZIFQYXHLE-OAAAQFAESA-N	590310	US11560385, Compound 91B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590310&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290572	479268874							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247416	Cc1cc(C(=O)CN2[C@@H]3CC4OC(C[C@H]24)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H23N3O2/c1-13-7-19(14(2)25(13)16-5-3-15(11-23)4-6-16)21(26)12-24-17-8-18-10-20(24)22(9-17)27-18/h3-7,17-18,20,22H,8-10,12H2,1-2H3/t17-,18?,20-,22?/m0/s1	LQXPNTHQZRZTIM-SDVIQFSTSA-N	590311	US11560385, Compound 92B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590311&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290816	479268875							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247417	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1cc(F)c(C#N)c(F)c1	InChI=1S/C21H21F2N3O2/c1-11-5-15(21(28)10-25-13-3-4-19(25)20(27)8-13)12(2)26(11)14-6-17(22)16(9-24)18(23)7-14/h5-7,13,19-20,27H,3-4,8,10H2,1-2H3/t13?,19?,20-/m0/s1	DUVDLAFKCGJXSM-NVWHIDKOSA-N	590312	US11560385, Compound 94B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590312&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290656	479268876							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247418	Cc1c(C#N)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O2/c1-13-18(11-24)22(14(2)26(13)16-5-3-15(10-23)4-6-16)21(28)12-25-17-7-8-19(25)20(27)9-17/h3-6,17,19-20,27H,7-9,12H2,1-2H3/t17?,19?,20-/m0/s1	KXBSELPNVWQCTM-UUKMXZOPSA-N	590259	US11560385, Compound 33B::US11560385, Compound 95B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590259&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290667	479268823							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247419	Cc1c(cc(Cl)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C20H20ClN3O2/c1-12-16(19(26)11-23-15-6-7-17(23)18(25)8-15)9-20(21)24(12)14-4-2-13(10-22)3-5-14/h2-5,9,15,17-18,25H,6-8,11H2,1H3/t15?,17?,18-/m0/s1	QFDOPEVZZJQNOR-VJFUWPCTSA-N	590314	US11560385, Compound 96B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590314&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290798	479268877							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247420	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c(Cl)c(Cl)n1-c1ccc(cc1)C#N	InChI=1S/C20H19Cl2N3O2/c1-11-18(17(27)10-24-14-6-7-15(24)16(26)8-14)19(21)20(22)25(11)13-4-2-12(9-23)3-5-13/h2-5,14-16,26H,6-8,10H2,1H3/t14?,15?,16-/m0/s1	SRFWIMOEWDZOQT-GPANFISMSA-N	590315	US11560385, Compound 97B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590315&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290654	479268878							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247421	Cc1c(cc(C2CC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C23H25N3O2/c1-14-19(23(28)13-25-18-8-9-20(25)22(27)10-18)11-21(16-4-5-16)26(14)17-6-2-15(12-24)3-7-17/h2-3,6-7,11,16,18,20,22,27H,4-5,8-10,13H2,1H3/t18?,20?,22-/m0/s1	MFTWBJQKFCPGCE-ZNIKRAEXSA-N	590316	US11560385, Compound 98B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590316&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290674	479268879							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247422	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(C#N)c(F)c1F	InChI=1S/C21H21F2N3O2/c1-11-7-15(19(28)10-25-14-4-6-16(25)18(27)8-14)12(2)26(11)17-5-3-13(9-24)20(22)21(17)23/h3,5,7,14,16,18,27H,4,6,8,10H2,1-2H3/t14?,16?,18-/m0/s1	GEYVTIHJYIDYCJ-PVARCSIZSA-N	590317	US11560385, Compound 99B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590317&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290657	479268880							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247423	C[C@H]1CC2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C22H25N3O/c1-14-10-19-8-9-21(14)24(19)13-22(26)20-11-15(2)25(16(20)3)18-6-4-17(12-23)5-7-18/h4-7,11,14,19,21H,8-10,13H2,1-3H3/t14-,19?,21?/m0/s1	IAHRKAGDZGCFPY-ZENHMJIWSA-N	590319	US11560385, Compound 100B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590319&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290575	479268882							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247424	C[C@H]1CC2CCC1N2CC(=O)c1c(C)n(c(C)c1F)-c1ccc(cc1)C#N	InChI=1S/C22H24FN3O/c1-13-10-18-8-9-19(13)25(18)12-20(27)21-14(2)26(15(3)22(21)23)17-6-4-16(11-24)5-7-17/h4-7,13,18-19H,8-10,12H2,1-3H3/t13-,18?,19?/m0/s1	RUGFCFQJOZFXJD-MDAWKPQNSA-N	590320	US11560385, Compound 101B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590320&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386474	479268883							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247425	Cc1cc(C(=O)CN2C3CCC2[C@H](C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H22F3N3O/c1-13-9-18(14(2)28(13)16-5-3-15(11-26)4-6-16)21(29)12-27-17-7-8-20(27)19(10-17)22(23,24)25/h3-6,9,17,19-20H,7-8,10,12H2,1-2H3/t17?,19-,20?/m0/s1	BMTONVKSFOUUTN-SYYJFZTOSA-N	590321	US11560385, Compound 102B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590321&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290686	479268884							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247426	Cc1c(F)c(C(=O)CN2C3CCC2[C@H](C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H21F4N3O/c1-12-20(21(23)13(2)29(12)15-5-3-14(10-27)4-6-15)19(30)11-28-16-7-8-18(28)17(9-16)22(24,25)26/h3-6,16-18H,7-9,11H2,1-2H3/t16?,17-,18?/m0/s1	VVIOHUFPRYYZDZ-ADKAHSJRSA-N	590322	US11560385, Compound 103B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590322&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290583	479268885							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247427	Cc1c(F)c(C(=O)CN2C3CCC2CC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C21H22FN3O/c1-13-20(19(26)12-24-16-7-8-17(24)10-9-16)21(22)14(2)25(13)18-5-3-15(11-23)4-6-18/h3-6,16-17H,7-10,12H2,1-2H3	AMUXQRPFQSXBNR-UHFFFAOYSA-N	590323	US11560385, Compound 104B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590323&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274655	479268886							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247428	Cc1cc(C(=O)CN2C3CCC2[C@H](C3)OC(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H22F3N3O2/c1-13-9-18(14(2)28(13)16-5-3-15(11-26)4-6-16)20(29)12-27-17-7-8-19(27)21(10-17)30-22(23,24)25/h3-6,9,17,19,21H,7-8,10,12H2,1-2H3/t17?,19?,21-/m0/s1	QVPKNTKBAJMSKZ-XTXLOEGASA-N	590324	US11560385, Compound 105B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590324&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			149105656	479268887							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247429	Cc1cc(C(=O)CN2C3CCC2[C@@H]2COC[C@H]32)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H25N3O2/c1-14-9-18(15(2)26(14)17-5-3-16(10-24)4-6-17)23(27)11-25-21-7-8-22(25)20-13-28-12-19(20)21/h3-6,9,19-22H,7-8,11-13H2,1-2H3/t19-,20+,21?,22?	RIPAGZJJJUPMHV-FDRBHKFBSA-N	590325	US11560385, Compound 106B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590325&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290607	479268888							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247430	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1cc(F)c(cc1F)C#N	InChI=1S/C21H21F2N3O2/c1-11-5-15(21(28)10-25-14-3-4-18(25)20(27)7-14)12(2)26(11)19-8-16(22)13(9-24)6-17(19)23/h5-6,8,14,18,20,27H,3-4,7,10H2,1-2H3/t14?,18?,20-/m0/s1	IAUSPTXURJBJOE-OQRDJCCKSA-N	590326	US11560385, Compound 107B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590326&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147883066	479268889							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247431	Cc1c(cc(C2CCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H27N3O2/c1-15-20(24(29)14-26-19-9-10-21(26)23(28)11-19)12-22(17-3-2-4-17)27(15)18-7-5-16(13-25)6-8-18/h5-8,12,17,19,21,23,28H,2-4,9-11,14H2,1H3/t19?,21?,23-/m0/s1	DZEDZSQAZNVHHP-IRSIHTCSSA-N	590327	US11560385, Compound 108B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590327&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290542	479268890							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247432	Cc1c(cc(n1-c1ccc(cc1)C#N)C(F)(F)F)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C21H20F3N3O2/c1-12-16(19(29)11-26-15-6-7-17(26)18(28)8-15)9-20(21(22,23)24)27(12)14-4-2-13(10-25)3-5-14/h2-5,9,15,17-18,28H,6-8,11H2,1H3/t15?,17?,18-/m0/s1	SEUHMHJAXXGJEQ-VJFUWPCTSA-N	590328	US11560385, Compound 109B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590328&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290536	479268891							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247433	Cc1c(cc(C2CCCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H29N3O2/c1-16-21(25(30)15-27-20-10-11-22(27)24(29)12-20)13-23(18-4-2-3-5-18)28(16)19-8-6-17(14-26)7-9-19/h6-9,13,18,20,22,24,29H,2-5,10-12,15H2,1H3/t20?,22?,24-/m0/s1	WJFMXISZOADXQE-JVPYDEADSA-N	590330	US11560385, Compound 110B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590330&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290548	479268892							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247434	Cc1c(cc(C2CCCCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H31N3O2/c1-17-22(26(31)16-28-21-11-12-23(28)25(30)13-21)14-24(19-5-3-2-4-6-19)29(17)20-9-7-18(15-27)8-10-20/h7-10,14,19,21,23,25,30H,2-6,11-13,16H2,1H3/t21?,23?,25-/m0/s1	RUWGBXMQMJWYLJ-GCKKQHTFSA-N	590331	US11560385, Compound 111B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590331&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290709	479268893							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247435	CC(C)c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-14(2)21-11-19(15(3)26(21)17-6-4-16(12-24)5-7-17)23(28)13-25-18-8-9-20(25)22(27)10-18/h4-7,11,14,18,20,22,27H,8-10,13H2,1-3H3/t18?,20?,22-/m0/s1	AFGRKWRNNADJLE-ZNIKRAEXSA-N	590332	US11560385, Compound 112B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590332&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290670	479268894							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247436	Cc1c(cc(n1-c1ccc(cc1)C#N)C(C)(C)C)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H29N3O2/c1-15-19(22(29)14-26-18-9-10-20(26)21(28)11-18)12-23(24(2,3)4)27(15)17-7-5-16(13-25)6-8-17/h5-8,12,18,20-21,28H,9-11,14H2,1-4H3/t18?,20?,21-/m0/s1	ALVQORRXLVKMGB-MNLRITNHSA-N	590333	US11560385, Compound 113B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590333&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290669	479268895							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247437	CCC(C)c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H29N3O2/c1-4-15(2)22-12-20(16(3)27(22)18-7-5-17(13-25)6-8-18)24(29)14-26-19-9-10-21(26)23(28)11-19/h5-8,12,15,19,21,23,28H,4,9-11,14H2,1-3H3/t15?,19?,21?,23-/m0/s1	QITMVVJHURMGAF-WPQQESAOSA-N	590334	US11560385, Compound 114B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590334&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290668	479268896							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247438	Cc1c(cc(CC(F)(F)F)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C22H22F3N3O2/c1-13-18(21(30)12-27-16-6-7-19(27)20(29)9-16)8-17(10-22(23,24)25)28(13)15-4-2-14(11-26)3-5-15/h2-5,8,16,19-20,29H,6-7,9-10,12H2,1H3/t16?,19?,20-/m0/s1	GEQKVDKSOJMMPF-GQOXECLESA-N	590335	US11560385, Compound 115B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590335&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147625229	479268897							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247439	Cc1c(F)c(C(=O)CN2C3CC4CC2CC(C3)O4)c(C)n1-c1ccc(C#N)c(F)c1	InChI=1S/C23H23F2N3O2/c1-12-22(21(29)11-27-16-5-18-7-17(27)8-19(6-16)30-18)23(25)13(2)28(12)15-4-3-14(10-26)20(24)9-15/h3-4,9,16-19H,5-8,11H2,1-2H3	QFDSOFOZLSNEHV-UHFFFAOYSA-N	590336	US11560385, Compound 116B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590336&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386598	479268898							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247440	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(Cl)c(F)c1	InChI=1S/C20H22ClFN2O2/c1-11-7-15(12(2)24(11)14-3-5-16(21)17(22)8-14)20(26)10-23-13-4-6-18(23)19(25)9-13/h3,5,7-8,13,18-19,25H,4,6,9-10H2,1-2H3/t13?,18?,19-/m0/s1	NJTSWMXJRBKTBW-PSMHFXKOSA-N	590337	US11560385, Compound 117B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590337&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290659	479268899							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247441	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1cc(F)c(Cl)c(F)c1	InChI=1S/C20H21ClF2N2O2/c1-10-5-14(19(27)9-24-12-3-4-17(24)18(26)8-12)11(2)25(10)13-6-15(22)20(21)16(23)7-13/h5-7,12,17-18,26H,3-4,8-9H2,1-2H3/t12?,17?,18-/m0/s1	CTLYZWLGNYYYIO-WQHGFJKVSA-N	590338	US11560385, Compound 118B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590338&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290687	479268900							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247442	Cc1c(cc(Br)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C20H20BrN3O2/c1-12-16(19(26)11-23-15-6-7-17(23)18(25)8-15)9-20(21)24(12)14-4-2-13(10-22)3-5-14/h2-5,9,15,17-18,25H,6-8,11H2,1H3/t15?,17?,18-/m0/s1	AVYIZKHWTGPZGF-VJFUWPCTSA-N	590342	US11560385, Compound 119B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590342&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156291097	479268901							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247443	Cc1c(F)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(C#N)c(F)c1	InChI=1S/C21H21F2N3O2/c1-11-20(19(28)10-25-14-5-6-17(25)18(27)8-14)21(23)12(2)26(11)15-4-3-13(9-24)16(22)7-15/h3-4,7,14,17-18,27H,5-6,8,10H2,1-2H3/t14?,17?,18-/m0/s1	KPGCYNSZRXWHNS-UYJHFMRCSA-N	590680	US11560385, Compound 120B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590680&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290683	479268902							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247444	C[C@@H]1CC2CCC1N2CC(=O)c1c(C)n(c(C)c1F)-c1ccc(cc1)C#N	InChI=1S/C22H24FN3O/c1-13-10-18-8-9-19(13)25(18)12-20(27)21-14(2)26(15(3)22(21)23)17-6-4-16(11-24)5-7-17/h4-7,13,18-19H,8-10,12H2,1-3H3/t13-,18?,19?/m1/s1	RUGFCFQJOZFXJD-XYJCDUHRSA-N	590681	US11560385, Compound 121B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590681&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290684	479268903							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247445	C[C@@H]1CC2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C22H25N3O/c1-14-10-19-8-9-21(14)24(19)13-22(26)20-11-15(2)25(16(20)3)18-6-4-17(12-23)5-7-18/h4-7,11,14,19,21H,8-10,13H2,1-3H3/t14-,19?,21?/m1/s1	IAHRKAGDZGCFPY-TVXIDFIASA-N	590682	US11560385, Compound 122B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590682&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290565	479268904							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247446	C[C@H]1[C@@H](C)C2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O/c1-14-11-20(17(4)26(14)19-7-5-18(12-24)6-8-19)23(27)13-25-21-9-10-22(25)16(3)15(21)2/h5-8,11,15-16,21-22H,9-10,13H2,1-4H3/t15-,16+,21?,22?	IJQWFMKDQRDBET-MBWAJUJLSA-N	590683	US11560385, Compound 124B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590683&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147929854	479268905							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247447	Cc1cc(C(=O)CN2C3CCC2(C)CC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O/c1-15-12-20(16(2)25(15)19-6-4-17(13-23)5-7-19)21(26)14-24-18-8-10-22(24,3)11-9-18/h4-7,12,18H,8-11,14H2,1-3H3	ZMKUSZPLNIPNPV-UHFFFAOYSA-N	590684	US11560385, Compound 125B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590684&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386864	479268906							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247448	Cc1cc(C(=O)CN2C3CCC2(CO)CC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-15-11-20(16(2)25(15)19-5-3-17(12-23)4-6-19)21(27)13-24-18-7-9-22(24,14-26)10-8-18/h3-6,11,18,26H,7-10,13-14H2,1-2H3	PKQTVIXDVSBXOB-UHFFFAOYSA-N	590685	US11560385, Compound 126B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590685&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274484	479268907							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247449	Cc1cc(C(=O)CN2C3CCC2(CC3)C(O)=O)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H23N3O3/c1-14-11-19(15(2)25(14)18-5-3-16(12-23)4-6-18)20(26)13-24-17-7-9-22(24,10-8-17)21(27)28/h3-6,11,17H,7-10,13H2,1-2H3,(H,27,28)	XXSSYLYNLHVBCW-UHFFFAOYSA-N	590686	US11560385, Compound 127B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590686&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386535	479268908							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247450	Cc1nc(Cc2c(Cl)c(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1	InChI=1S/C25H25ClN4O2S/c1-14-24(23(32)12-29-19-7-8-20(29)22(31)10-19)25(26)21(9-17-13-33-15(2)28-17)30(14)18-5-3-16(11-27)4-6-18/h3-6,13,19-20,22,31H,7-10,12H2,1-2H3/t19?,20?,22-/m0/s1	CPYXQLIEMRPVQG-AOMIVXANSA-N	590687	US11560385, Compound 128B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590687&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290676	479268909							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247451	Cc1nc(Cc2c(Br)c(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1	InChI=1S/C25H25BrN4O2S/c1-14-24(23(32)12-29-19-7-8-20(29)22(31)10-19)25(26)21(9-17-13-33-15(2)28-17)30(14)18-5-3-16(11-27)4-6-18/h3-6,13,19-20,22,31H,7-10,12H2,1-2H3/t19?,20?,22-/m0/s1	CRYFEMQVTJBPKU-AOMIVXANSA-N	590688	US11560385, Compound 129B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590688&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290651	479268910							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247452	Cc1cc(C(=O)CN2C3CCC2[C@@H](CO)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-9-20(15(2)25(14)18-5-3-16(11-23)4-6-18)22(27)12-24-19-7-8-21(24)17(10-19)13-26/h3-6,9,17,19,21,26H,7-8,10,12-13H2,1-2H3/t17-,19?,21?/m1/s1	CITYFCNBPRJJMW-FQVISZRSSA-N	590689	US11560385, Compound 130B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590689&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290677	479268911							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247453	Cc1c(cc(C2CC(F)(F)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H25F2N3O2/c1-14-19(23(31)13-28-18-6-7-20(28)22(30)8-18)9-21(16-10-24(25,26)11-16)29(14)17-4-2-15(12-27)3-5-17/h2-5,9,16,18,20,22,30H,6-8,10-11,13H2,1H3/t18?,20?,22-/m0/s1	PXXYKMSSWKLVCK-ZNIKRAEXSA-N	590690	US11560385, Compound 131B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590690&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156291078	479268912							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247454	Cc1c(cc(C2CC(F)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H26FN3O2/c1-14-20(24(30)13-27-19-6-7-21(27)23(29)10-19)11-22(16-8-17(25)9-16)28(14)18-4-2-15(12-26)3-5-18/h2-5,11,16-17,19,21,23,29H,6-10,13H2,1H3/t16?,17?,19?,21?,23-/m0/s1	DXFGBZNZTLLLJM-WUARHYPRSA-N	590691	US11560385, Compound 132B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590691&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290590	479268913							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247455	Cc1c(cc(CC2CCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H29N3O2/c1-16-22(25(30)15-27-20-9-10-23(27)24(29)13-20)12-21(11-17-3-2-4-17)28(16)19-7-5-18(14-26)6-8-19/h5-8,12,17,20,23-24,29H,2-4,9-11,13,15H2,1H3/t20?,23?,24-/m0/s1	JYESMSWWTMYXJM-BOYUCYPVSA-N	590692	US11560385, Compound 133B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590692&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156291180	479268914							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247456	Cc1c(cc(CC2CC(C)(C)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C27H33N3O2/c1-17-23(26(32)16-29-21-8-9-24(29)25(31)12-21)11-22(10-19-13-27(2,3)14-19)30(17)20-6-4-18(15-28)5-7-20/h4-7,11,19,21,24-25,31H,8-10,12-14,16H2,1-3H3/t21?,24?,25-/m0/s1	UESMPDPTTFEVAV-MTQWGCILSA-N	590693	US11560385, Compound 134B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590693&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290596	479268915							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247457	Cc1c(cc(CC2CC(F)(F)C2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H27F2N3O2/c1-15-21(24(32)14-29-19-6-7-22(29)23(31)10-19)9-20(8-17-11-25(26,27)12-17)30(15)18-4-2-16(13-28)3-5-18/h2-5,9,17,19,22-23,31H,6-8,10-12,14H2,1H3/t19?,22?,23-/m0/s1	IGJQGOSKVSZCAS-HXJXPZHGSA-N	590694	US11560385, Compound 135B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290587	479268916							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247458	C[C@H]1CC2CCC1N2CC(=O)c1cc(C#N)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C22H22N4O/c1-14-9-18-7-8-21(14)25(18)13-22(27)20-10-19(12-24)26(15(20)2)17-5-3-16(11-23)4-6-17/h3-6,10,14,18,21H,7-9,13H2,1-2H3/t14-,18?,21?/m0/s1	OHCMWUCHMQECRG-DFLTZVLMSA-N	590695	US11560385, Compound 136B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590695&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386492	479268917							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247459	Cc1c(cc(C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C21H20N4O/c1-14-20(21(26)13-24-16-6-7-17(24)9-8-16)10-19(12-23)25(14)18-4-2-15(11-22)3-5-18/h2-5,10,16-17H,6-9,13H2,1H3	YSAVJIAWSQIHHW-UHFFFAOYSA-N	590696	US11560385, Compound 137B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590696&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386507	479268918							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247460	C[C@H]1[C@@H](C)C2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O/c1-14-11-20(17(4)26(14)19-7-5-18(12-24)6-8-19)23(27)13-25-21-9-10-22(25)16(3)15(21)2/h5-8,11,15-16,21-22H,9-10,13H2,1-4H3/t15-,16+,21?,22?	IJQWFMKDQRDBET-MBWAJUJLSA-N	590697	US11560385, Compound 138B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590697&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147929854	479268919							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247461	Cc1cc(C(=O)CN2C3CCC2[C@@H]2OCC[C@H]32)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H25N3O2/c1-14-11-19(15(2)26(14)17-5-3-16(12-24)4-6-17)22(27)13-25-20-7-8-21(25)23-18(20)9-10-28-23/h3-6,11,18,20-21,23H,7-10,13H2,1-2H3/t18-,20?,21?,23-/m1/s1	GCOGFZCQNFEDJF-UKHOHEFJSA-N	590698	US11560385, Compound 139B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590698&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290546	479268920							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247462	C[C@H]1[C@H](C)C2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O/c1-14-11-20(17(4)26(14)19-7-5-18(12-24)6-8-19)23(27)13-25-21-9-10-22(25)16(3)15(21)2/h5-8,11,15-16,21-22H,9-10,13H2,1-4H3/t15-,16-,21?,22?/m0/s1	IJQWFMKDQRDBET-TUKZGULFSA-N	590699	US11560385, Compound 140B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590699&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677918	479268921							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247463	Cc1cc(C(=O)CN2C3CCC2C(=C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H20F3N3O/c1-13-9-18(14(2)28(13)16-5-3-15(11-26)4-6-16)21(29)12-27-17-7-8-20(27)19(10-17)22(23,24)25/h3-6,9-10,17,20H,7-8,12H2,1-2H3	WYLBVMVSEILEPC-UHFFFAOYSA-N	590700	US11560385, Compound 141B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590700&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290672	479268922							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247464	C[C@@H]1C[C@H]1c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H27N3O2/c1-14-9-19(14)22-11-20(15(2)27(22)17-5-3-16(12-25)4-6-17)24(29)13-26-18-7-8-21(26)23(28)10-18/h3-6,11,14,18-19,21,23,28H,7-10,13H2,1-2H3/t14-,18?,19-,21?,23+/m1/s1	HHZSPSOALFARHK-NQJMBJCNSA-N	590701	US11560385, Compound 142B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590701&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290580	479268923							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247301	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H29ClN2O3S/c1-17-26(25(30)16-28-20-8-9-21(28)11-10-20)23-12-3-18(13-14-33(2,31)32)15-24(23)29(17)22-6-4-19(27)5-7-22/h3-7,12,15,20-21H,8-11,13-14,16H2,1-2H3	CWYMIWPKSBGNTL-UHFFFAOYSA-N	590191	US11560385, Compound 1A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590191&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147305646	479268757							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247302	Cc1c(C(=O)CN2C3CCC2CCC3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H31ClN2O3S/c1-18-27(26(31)17-29-21-4-3-5-22(29)12-11-21)24-13-6-19(14-15-34(2,32)33)16-25(24)30(18)23-9-7-20(28)8-10-23/h6-10,13,16,21-22H,3-5,11-12,14-15,17H2,1-2H3	NUVDTZFHHSRTBQ-UHFFFAOYSA-N	590192	US11560385, Compound 2A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590192&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290606	479268758							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247303	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C25H27ClN2O3S/c1-16-25(24(29)14-27-19-8-9-20(27)11-10-19)22-12-3-17(15-32(2,30)31)13-23(22)28(16)21-6-4-18(26)5-7-21/h3-7,12-13,19-20H,8-11,14-15H2,1-2H3	CSPPTXUASOFQIS-UHFFFAOYSA-N	590193	US11560385, Compound 3A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590193&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			149957891	479268759							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247304	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H31ClN2O4S/c1-17-27(26(32)16-29-21-8-9-22(29)15-23(31)14-21)24-10-3-18(11-12-35(2,33)34)13-25(24)30(17)20-6-4-19(28)5-7-20/h3-7,10,13,21-23,31H,8-9,11-12,14-16H2,1-2H3	BGZUTDOSZXTLKH-UHFFFAOYSA-N	590194	US11560385, Compound 4A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590194&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290525	479268760							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247305	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H31ClN2O4S/c1-17-27(26(32)16-29-21-8-9-22(29)15-23(31)14-21)24-10-3-18(11-12-35(2,33)34)13-25(24)30(17)20-6-4-19(28)5-7-20/h3-7,10,13,21-23,31H,8-9,11-12,14-16H2,1-2H3	BGZUTDOSZXTLKH-UHFFFAOYSA-N	590195	US11560385, Compound 5A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590195&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290525	479268761							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247306	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H29ClN2O4S/c1-16-26(25(31)15-28-20-8-10-22(28)24(30)14-20)21-9-3-17(11-12-34(2,32)33)13-23(21)29(16)19-6-4-18(27)5-7-19/h3-7,9,13,20,22,24,30H,8,10-12,14-15H2,1-2H3/t20?,22?,24-/m0/s1	LVDWNUYJANTLPQ-JVPYDEADSA-N	590196	US11560385, Compound 6A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590196&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290605	479268762							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247307	Cc1c(C(=O)CN2CCC(O)CC2)c2ccc(CCS(C)(=O)=O)cc2n1-c1ccc(Cl)cc1	InChI=1S/C25H29ClN2O4S/c1-17-25(24(30)16-27-12-9-21(29)10-13-27)22-8-3-18(11-14-33(2,31)32)15-23(22)28(17)20-6-4-19(26)5-7-20/h3-8,15,21,29H,9-14,16H2,1-2H3	IQARSSZZPGQMFC-UHFFFAOYSA-N	590197	US11560385, Compound 7A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590197&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386633	479268763							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247308	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H26ClN3O/c1-17-26(25(31)16-29-20-9-10-21(29)12-11-20)23-13-4-18(3-2-14-28)15-24(23)30(17)22-7-5-19(27)6-8-22/h4-8,13,15,20-21H,2-3,9-12,16H2,1H3	UZCQXFLPHOBDPF-UHFFFAOYSA-N	590198	US11560385, Compound 8A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590198&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386469	479268764							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247309	Cc1c(C(=O)CN2CCC(O)CC2)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C25H26ClN3O2/c1-17-25(24(31)16-28-13-10-21(30)11-14-28)22-9-4-18(3-2-12-27)15-23(22)29(17)20-7-5-19(26)6-8-20/h4-9,15,21,30H,2-3,10-11,13-14,16H2,1H3	CKNACTRSRILXAV-UHFFFAOYSA-N	590199	US11560385, Compound 9A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590199&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386829	479268765							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247310	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H26ClN3O2/c1-16-26(25(32)15-29-20-9-11-22(29)24(31)14-20)21-10-4-17(3-2-12-28)13-23(21)30(16)19-7-5-18(27)6-8-19/h4-8,10,13,20,22,24,31H,2-3,9,11,14-15H2,1H3/t20?,22?,24-/m0/s1	XBIMVGSHAOVKNH-JVPYDEADSA-N	590200	US11560385, Compound 10A::US11560385, Compound 15A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590200&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274585	479268766							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247311	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H29ClN2O2/c1-17-27(26(31)14-29-21-7-8-22(29)10-9-21)24-11-2-18(12-19-15-32-16-19)13-25(24)30(17)23-5-3-20(28)4-6-23/h2-6,11,13,19,21-22H,7-10,12,14-16H2,1H3	XLDDHVTUZKXWLY-UHFFFAOYSA-N	590201	US11560385, Compound 11A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590201&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386603	479268767							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247312	Cc1c(C(=O)CN2C3CCC2[C@@H](CO)C3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H31ClN2O3/c1-17-28(27(33)13-30-23-7-9-25(30)20(12-23)14-32)24-8-2-18(10-19-15-34-16-19)11-26(24)31(17)22-5-3-21(29)4-6-22/h2-6,8,11,19-20,23,25,32H,7,9-10,12-16H2,1H3/t20-,23?,25?/m1/s1	MCYFRGBBDZLKIA-LQRWPSFBSA-N	590202	US11560385, Compound 12A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590202&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677913	479268768							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247313	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H29ClN2O3/c1-16-27(26(32)13-29-21-7-9-23(29)25(31)12-21)22-8-2-17(10-18-14-33-15-18)11-24(22)30(16)20-5-3-19(28)4-6-20/h2-6,8,11,18,21,23,25,31H,7,9-10,12-15H2,1H3/t21?,23?,25-/m0/s1	PILBYPFVELLWQX-GCKKQHTFSA-N	590203	US11560385, Compound 13A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590203&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290666	479268769							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247314	Cc1c(C(=O)CN2CCC(O)CC2)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H29ClN2O3/c1-17-26(25(31)14-28-10-8-22(30)9-11-28)23-7-2-18(12-19-15-32-16-19)13-24(23)29(17)21-5-3-20(27)4-6-21/h2-7,13,19,22,30H,8-12,14-16H2,1H3	XYAPPYLAMGZGDV-UHFFFAOYSA-N	590204	US11560385, Compound 14A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590204&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386876	479268770							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247315	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C26H26ClN3O2/c1-16-26(25(32)15-29-20-9-11-22(29)24(31)14-20)21-10-4-17(3-2-12-28)13-23(21)30(16)19-7-5-18(27)6-8-19/h4-8,10,13,20,22,24,31H,2-3,9,11,14-15H2,1H3/t20?,22?,24-/m0/s1	XBIMVGSHAOVKNH-JVPYDEADSA-N	590200	US11560385, Compound 10A::US11560385, Compound 15A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590200&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274585	479268766							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247316	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H31ClN2O3S/c1-18-28(27(32)17-30-21-7-8-22(30)10-9-21)25-13-2-19(14-15-35(33,34)24-11-12-24)16-26(25)31(18)23-5-3-20(29)4-6-23/h2-6,13,16,21-22,24H,7-12,14-15,17H2,1H3	ASYAZPNSGJCHCM-UHFFFAOYSA-N	590206	US11560385, Compound 16A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590206&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274705	479268771							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247317	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H28ClN3O/c1-18-27(26(32)17-30-21-10-11-22(30)13-12-21)24-14-5-19(4-2-3-15-29)16-25(24)31(18)23-8-6-20(28)7-9-23/h5-9,14,16,21-22H,2-4,10-13,17H2,1H3	NAZFPUUIGUDVRW-UHFFFAOYSA-N	590207	US11560385, Compound 17A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590207&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386485	479268772							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247318	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H28ClN3O2/c1-17-27(26(33)16-30-21-10-12-23(30)25(32)15-21)22-11-5-18(4-2-3-13-29)14-24(22)31(17)20-8-6-19(28)7-9-20/h5-9,11,14,21,23,25,32H,2-4,10,12,15-16H2,1H3/t21?,23?,25-/m0/s1	KYKXVHFCVPYPCI-GCKKQHTFSA-N	590208	US11560385, Compound 18A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590208&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386742	479268773							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247319	Cc1c(C(=O)CN2C3CCC2[C@@H](CO)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H30ClN3O2/c1-18-28(27(34)16-31-23-10-12-25(31)20(15-23)17-33)24-11-5-19(4-2-3-13-30)14-26(24)32(18)22-8-6-21(29)7-9-22/h5-9,11,14,20,23,25,33H,2-4,10,12,15-17H2,1H3/t20-,23?,25?/m1/s1	KWDZIGUGJXTGLX-LQRWPSFBSA-N	590209	US11560385, Compound 19A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590209	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590209&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677911	479268774							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247320	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H28ClN3O2/c1-17-27(26(33)16-30-21-9-10-22(30)15-23(32)14-21)24-11-4-18(3-2-12-29)13-25(24)31(17)20-7-5-19(28)6-8-20/h4-8,11,13,21-23,32H,2-3,9-10,14-16H2,1H3	VOPUGFREUZJIME-UHFFFAOYSA-N	590210	US11560385, Compound 20A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590210&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386722	479268775							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247321	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H28ClN3O2/c1-17-27(26(33)16-30-21-9-10-22(30)15-23(32)14-21)24-11-4-18(3-2-12-29)13-25(24)31(17)20-7-5-19(28)6-8-20/h4-8,11,13,21-23,32H,2-3,9-10,14-16H2,1H3	VOPUGFREUZJIME-UHFFFAOYSA-N	590211	US11560385, Compound 21A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590211&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386722	479268776							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247322	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H31ClN2O3/c1-17-28(27(33)14-30-22-7-8-23(30)13-24(32)12-22)25-9-2-18(10-19-15-34-16-19)11-26(25)31(17)21-5-3-20(29)4-6-21/h2-6,9,11,19,22-24,32H,7-8,10,12-16H2,1H3	KLKKLCHOKAQPPX-UHFFFAOYSA-N	590212	US11560385, Compound 22A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590212&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148218601	479268777							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247323	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C29H33ClN2O4S/c1-18-29(28(34)17-31-22-7-8-23(31)16-24(33)15-22)26-11-2-19(12-13-37(35,36)25-9-10-25)14-27(26)32(18)21-5-3-20(30)4-6-21/h2-6,11,14,22-25,33H,7-10,12-13,15-17H2,1H3	LKPPTJJMUKAJBD-UHFFFAOYSA-N	590213	US11560385, Compound 23A::US11560385, Compound 24A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590213&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148361877	479268778							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247324	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C29H33ClN2O4S/c1-18-29(28(34)17-31-22-7-8-23(31)16-24(33)15-22)26-11-2-19(12-13-37(35,36)25-9-10-25)14-27(26)32(18)21-5-3-20(30)4-6-21/h2-6,11,14,22-25,33H,7-10,12-13,15-17H2,1H3	LKPPTJJMUKAJBD-UHFFFAOYSA-N	590213	US11560385, Compound 23A::US11560385, Compound 24A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590213&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148361877	479268778							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247325	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H30ClN3O2/c1-18-28(27(34)17-31-22-10-11-23(31)16-24(33)15-22)25-12-5-19(4-2-3-13-30)14-26(25)32(18)21-8-6-20(29)7-9-21/h5-9,12,14,22-24,33H,2-4,10-11,15-17H2,1H3	KOVRSLOTUOBCNP-UHFFFAOYSA-N	590215	US11560385, Compound 25A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590215&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148236765	479268779							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247326	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H30ClN3O2/c1-18-28(27(34)17-31-22-10-11-23(31)16-24(33)15-22)25-12-5-19(4-2-3-13-30)14-26(25)32(18)21-8-6-20(29)7-9-21/h5-9,12,14,22-24,33H,2-4,10-11,15-17H2,1H3	KOVRSLOTUOBCNP-UHFFFAOYSA-N	590216	US11560385, Compound 26A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590216&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148236765	479268780							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247327	Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CC3COC3)cc2n1-c1ccc(Cl)cc1	InChI=1S/C28H31ClN2O3/c1-17-28(27(33)14-30-22-7-8-23(30)13-24(32)12-22)25-9-2-18(10-19-15-34-16-19)11-26(25)31(17)21-5-3-20(29)4-6-21/h2-6,9,11,19,22-24,32H,7-8,10,12-16H2,1H3	KLKKLCHOKAQPPX-UHFFFAOYSA-N	590217	US11560385, Compound 27A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590217&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			148218601	479268781							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247328	CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C30H35ClN4O2/c1-19-30(28(37)18-34-23-9-10-24(34)17-25(36)16-23)26-11-3-20(4-12-29-32-13-14-33(29)2)15-27(26)35(19)22-7-5-21(31)6-8-22/h3,5-8,11,15,23-25,36H,4,9-10,12-14,16-18H2,1-2H3	IKPUVGUJOXRHIJ-UHFFFAOYSA-N	590218	US11560385, Compound 28A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590218&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147934977	479268782							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247329	CN1CCN=C1CCc1ccc2c(C(=O)CN3C4CCC3CC(O)C4)c(C)n(-c3ccc(Cl)cc3)c2c1	InChI=1S/C30H35ClN4O2/c1-19-30(28(37)18-34-23-9-10-24(34)17-25(36)16-23)26-11-3-20(4-12-29-32-13-14-33(29)2)15-27(26)35(19)22-7-5-21(31)6-8-22/h3,5-8,11,15,23-25,36H,4,9-10,12-14,16-18H2,1-2H3	IKPUVGUJOXRHIJ-UHFFFAOYSA-N	590219	US11560385, Compound 29A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590219&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147934977	479268783							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247330	Cc1c(C(=O)CN2C3CCC2CC3)c2ccc(CC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C25H24ClN3O/c1-16-25(24(30)15-28-19-7-8-20(28)10-9-19)22-11-2-17(12-13-27)14-23(22)29(16)21-5-3-18(26)4-6-21/h2-6,11,14,19-20H,7-10,12,15H2,1H3	GCWLFOUZCYLWCS-UHFFFAOYSA-N	590220	US11560385, Compound 30A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590220&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386460	479268784							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247331	Cc1c(C(=O)CN2C3CC[C@@H]2C[C@@](O)(C3)C(C)(C)C)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C31H36ClN3O2/c1-20-29(28(36)19-34-24-12-13-25(34)18-31(37,17-24)30(2,3)4)26-14-7-21(6-5-15-33)16-27(26)35(20)23-10-8-22(32)9-11-23/h7-11,14,16,24-25,37H,5-6,12-13,17-19H2,1-4H3/t24-,25?,31-/m1/s1	RUIJTWDBTCGGKM-GZFNOXKJSA-N	590221	US11560385, Compound 31A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>100							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590221&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677928	479268785							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247332	CC(C)C1(O)CC2CCC(C1)N2CC(=O)c1c(C)n(-c2ccc(Cl)cc2)c2cc(CCC#N)ccc12	InChI=1S/C30H34ClN3O2/c1-19(2)30(36)16-24-11-12-25(17-30)33(24)18-28(35)29-20(3)34(23-9-7-22(31)8-10-23)27-15-21(5-4-14-32)6-13-26(27)29/h6-10,13,15,19,24-25,36H,4-5,11-12,16-18H2,1-3H3	CDPHPYVMVAUWCM-UHFFFAOYSA-N	590222	US11560385, Compound 32A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 75							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590222	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590222&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274504	479268786							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247333	Cc1c(C(=O)CN2C3CCC2CCC3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1	InChI=1S/C27H28ClN3O/c1-18-27(26(32)17-30-21-5-2-6-22(30)13-12-21)24-14-7-19(4-3-15-29)16-25(24)31(18)23-10-8-20(28)9-11-23/h7-11,14,16,21-22H,2-6,12-13,17H2,1H3	YNWSGJLMVBPIKC-UHFFFAOYSA-N	590223	US11560385, Compound 33A	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590223	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590223&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274514	479268787							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247334	Cc1c(CCCCS(C)(=O)=O)n(c(C)c1C(=O)CN1C2CCC1CC2)-c1ccc(cc1)C#N	InChI=1S/C26H33N3O3S/c1-18-24(6-4-5-15-33(3,31)32)29(23-9-7-20(16-27)8-10-23)19(2)26(18)25(30)17-28-21-11-12-22(28)14-13-21/h7-10,21-22H,4-6,11-15,17H2,1-3H3	LXUZVIPMCRGZCH-UHFFFAOYSA-N	590224	US11560385, Compound 1B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590224&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386512	479268788							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247335	Cc1c(cc(CCCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C28H35N3O3/c1-19-25(28(33)18-30-23-9-10-26(30)27(32)16-23)15-24(4-2-3-20-11-13-34-14-12-20)31(19)22-7-5-21(17-29)6-8-22/h5-8,15,20,23,26-27,32H,2-4,9-14,16,18H2,1H3/t23?,26?,27-/m0/s1	IISDWRVHKLFNJY-YTZIBCIGSA-N	590226	US11560385, Compound 2B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590226&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290671	479268790							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247336	Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C25H24N4O/c1-18-24(25(30)17-28-20-10-11-21(28)13-12-20)15-23(5-3-2-4-14-26)29(18)22-8-6-19(16-27)7-9-22/h6-9,15,20-21H,2,4,10-13,17H2,1H3	ZWVCJEUZTWICPB-UHFFFAOYSA-N	590227	US11560385, Compound 3B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590227&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274765	479268791							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247337	Cc1c(cc(C[C@H]2C[C@H](C2)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H28N4O2/c1-16-23(26(32)15-29-21-6-7-24(29)25(31)12-21)11-22(10-18-8-19(9-18)14-28)30(16)20-4-2-17(13-27)3-5-20/h2-5,11,18-19,21,24-25,31H,6-10,12,15H2,1H3/t18-,19+,21?,24?,25-/m0/s1	UOSHLWUFYYVZCT-IOAOTNJNSA-N	590228	US11560385, Compound 4B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590228&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			152951067	479268792							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247338	Cc1c(cc(COCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H26N4O3/c1-16-21(24(30)14-27-19-7-8-22(27)23(29)12-19)11-20(15-31-10-2-9-25)28(16)18-5-3-17(13-26)4-6-18/h3-6,11,19,22-23,29H,2,7-8,10,12,14-15H2,1H3/t19?,22?,23-/m0/s1	MLRBBEZYVFOWNU-HXJXPZHGSA-N	590229	US11560385, Compound 5B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590229&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290604	479268793							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247339	Cc1nccn1C\C=C\c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C27H29N5O2/c1-18-24(27(34)17-31-22-9-10-25(31)26(33)15-22)14-23(4-3-12-30-13-11-29-19(30)2)32(18)21-7-5-20(16-28)6-8-21/h3-8,11,13-14,22,25-26,33H,9-10,12,15,17H2,1-2H3/b4-3+/t22?,25?,26-/m0/s1	ZZJCZIPPLNUWQM-GKLQBJHLSA-N	590230	US11560385, Compound 6B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590230&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290698	479268794							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247340	Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1[C@@H]2CC[C@@H]1CC(O)C2	InChI=1S/C26H33N3O4S/c1-18-25(26(31)17-28-21-10-11-22(28)14-24(30)13-21)15-23(5-3-4-12-34(2,32)33)29(18)20-8-6-19(16-27)7-9-20/h6-9,15,21-22,24,30H,3-5,10-14,17H2,1-2H3/t21-,22-/m1/s1	IVZVKKNGRNVZHK-FGZHOGPDSA-N	590231	US11560385, Compound 7B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590231&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677929	479268795							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247341	Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H31N3O4S/c1-17-22(25(30)16-27-20-10-11-23(27)24(29)14-20)13-21(5-3-4-12-33(2,31)32)28(17)19-8-6-18(15-26)7-9-19/h6-9,13,20,23-24,29H,3-5,10-12,14,16H2,1-2H3/t20?,23?,24-/m0/s1	VOBWVXZMXMHAEY-BOYUCYPVSA-N	590232	US11560385, Compound 8B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590232&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290814	479268796							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247342	Cc1c(cc(CCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C27H33N3O3/c1-18-24(27(32)17-29-22-8-9-25(29)26(31)15-22)14-23(7-2-19-10-12-33-13-11-19)30(18)21-5-3-20(16-28)4-6-21/h3-6,14,19,22,25-26,31H,2,7-13,15,17H2,1H3/t22?,25?,26-/m0/s1	YRKVZUMCGVZZNR-BOPKNSRXSA-N	590233	US11560385, Compound 9B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590233&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290553	479268797							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247343	Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H24N4O2/c1-17-22(25(31)16-28-20-10-11-23(28)24(30)14-20)13-21(5-3-2-4-12-26)29(17)19-8-6-18(15-27)7-9-19/h6-9,13,20,23-24,30H,2,4,10-11,14,16H2,1H3/t20?,23?,24-/m0/s1	RFQZEKKPJPEAKO-BOYUCYPVSA-N	590234	US11560385, Compound 10B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590234&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290599	479268798							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247344	CC(CCS(C)(=O)=O)c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O4S/c1-16(10-11-33(3,31)32)23-13-21(17(2)28(23)19-6-4-18(14-26)5-7-19)25(30)15-27-20-8-9-22(27)24(29)12-20/h4-7,13,16,20,22,24,29H,8-12,15H2,1-3H3/t16?,20?,22?,24-/m0/s1	KRBCYGIXEVCFPX-WNNKTMKZSA-N	590235	US11560385, Compound 11B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590235&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290740	479268799							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247345	COCCCCc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O3/c1-17-22(25(30)16-27-20-10-11-23(27)24(29)14-20)13-21(5-3-4-12-31-2)28(17)19-8-6-18(15-26)7-9-19/h6-9,13,20,23-24,29H,3-5,10-12,14,16H2,1-2H3/t20?,23?,24-/m0/s1	NLOOEYYNNWDTGI-BOYUCYPVSA-N	590236	US11560385, Compound 12B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590236&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290551	479268800							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247346	COCCCCc1cc(C(=O)CN2C3CCC2[C@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O3/c1-17-22(25(30)16-27-20-10-11-23(27)24(29)14-20)13-21(5-3-4-12-31-2)28(17)19-8-6-18(15-26)7-9-19/h6-9,13,20,23-24,29H,3-5,10-12,14,16H2,1-2H3/t20?,23?,24-/m1/s1	NLOOEYYNNWDTGI-VZYOYLOZSA-N	590237	US11560385, Compound 13B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590237&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386792	479268801							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247347	Cc1c(cc(CCCCC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C29H37N3O3/c1-20-26(29(34)19-31-24-10-11-27(31)28(33)17-24)16-25(5-3-2-4-21-12-14-35-15-13-21)32(20)23-8-6-22(18-30)7-9-23/h6-9,16,21,24,27-28,33H,2-5,10-15,17,19H2,1H3/t24?,27?,28-/m0/s1	QKVOEYIEHBESQW-NMPMCGMKSA-N	590238	US11560385, Compound 14B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590238&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290700	479268802							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247348	Cc1c(cc(\C=C\CC(C)(C)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C27H30N4O2/c1-18-23(26(33)16-30-21-10-11-24(30)25(32)14-21)13-22(5-4-12-27(2,3)17-29)31(18)20-8-6-19(15-28)7-9-20/h4-9,13,21,24-25,32H,10-12,14,16H2,1-3H3/b5-4+/t21?,24?,25-/m0/s1	OXOCCLHXGMZMSN-OHMMPHKPSA-N	590239	US11560385, Compound 15B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590239&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290702	479268803							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247349	Cc1c(C(=O)CN2C3CCC2CC3)c(C)n(c1-c1ccc(cc1)C#N)-c1ccc(cc1)C#N	InChI=1S/C28H26N4O/c1-18-27(26(33)17-31-23-11-12-24(31)14-13-23)19(2)32(25-9-5-21(16-30)6-10-25)28(18)22-7-3-20(15-29)4-8-22/h3-10,23-24H,11-14,17H2,1-2H3	KKQXXZBLGLSJKI-UHFFFAOYSA-N	590240	US11560385, Compound 16B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590240&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386862	479268804							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247350	Cc1c(cc([C@@H]2C[C@H]2CCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H28N4O2/c1-16-21(26(32)15-29-20-8-9-23(29)25(31)12-20)13-24(22-11-18(22)3-2-10-27)30(16)19-6-4-17(14-28)5-7-19/h4-7,13,18,20,22-23,25,31H,2-3,8-9,11-12,15H2,1H3/t18-,20?,22-,23?,25+/m1/s1	DKQJKBNKTORXKT-RRDZWYPISA-N	590241	US11560385, Compound 17B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590241&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677924	479268805							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247351	Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(Cl)cc1)C(=O)CN1C2CCC1CC2	InChI=1S/C24H31ClN2O3S/c1-17-23(24(28)16-26-19-10-11-20(26)13-12-19)15-22(5-3-4-14-31(2,29)30)27(17)21-8-6-18(25)7-9-21/h6-9,15,19-20H,3-5,10-14,16H2,1-2H3	PGWKLXQPMBABBN-UHFFFAOYSA-N	590242	US11560385, Compound 18B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590242&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386787	479268806							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247352	Cc1c(CCCCS(C)(=O)=O)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C26H33N3O4S/c1-17-22(6-4-5-13-34(3,32)33)26(18(2)29(17)20-9-7-19(15-27)8-10-20)25(31)16-28-21-11-12-23(28)24(30)14-21/h7-10,21,23-24,30H,4-6,11-14,16H2,1-3H3/t21?,23?,24-/m0/s1	CLOSXGBECOPAER-HQNXYIODSA-N	590243	US11560385, Compound 19B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590243&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290645	479268807							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247353	Cc1c(cc(\C=C\CCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H26N4O2/c1-17-22(25(31)16-28-20-10-11-23(28)24(30)14-20)13-21(5-3-2-4-12-26)29(17)19-8-6-18(15-27)7-9-19/h3,5-9,13,20,23-24,30H,2,4,10-11,14,16H2,1H3/b5-3+/t20?,23?,24-/m0/s1	TWHMBSYOTWOIQW-OSIWGOIDSA-N	590244	US11560385, Compound 20B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590244&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290552	479268808							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247354	Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CC3CC1CC(C2)O3	InChI=1S/C27H26N4O2/c1-18-26(27(32)17-30-22-11-24-13-23(30)14-25(12-22)33-24)15-21(5-3-2-4-10-28)31(18)20-8-6-19(16-29)7-9-20/h6-9,15,22-25H,2,4,11-14,17H2,1H3	MZNMPMDPZVTVAI-UHFFFAOYSA-N	590245	US11560385, Compound 21B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590245&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386614	479268809							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247355	Cc1c(cc(CCCC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H31N3O3/c1-17-23(26(31)14-28-21-9-10-24(28)25(30)12-21)11-22(4-2-3-19-15-32-16-19)29(17)20-7-5-18(13-27)6-8-20/h5-8,11,19,21,24-25,30H,2-4,9-10,12,14-16H2,1H3/t21?,24?,25-/m0/s1	CUHMWNYATYDNAG-MTQWGCILSA-N	590246	US11560385, Compound 22B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590246&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290763	479268810							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247356	Cc1c(cc(CCCCC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C27H33N3O3/c1-18-24(27(32)15-29-22-10-11-25(29)26(31)13-22)12-23(5-3-2-4-20-16-33-17-20)30(18)21-8-6-19(14-28)7-9-21/h6-9,12,20,22,25-26,31H,2-5,10-11,13,15-17H2,1H3/t22?,25?,26-/m0/s1	IWPFOLOFLWOPOD-BOPKNSRXSA-N	590247	US11560385, Compound 23B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590247&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290543	479268811							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247357	Cc1c(cc(CCCn2cccn2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H29N5O2/c1-18-23(26(33)17-30-21-9-10-24(30)25(32)15-21)14-22(4-2-12-29-13-3-11-28-29)31(18)20-7-5-19(16-27)6-8-20/h3,5-8,11,13-14,21,24-25,32H,2,4,9-10,12,15,17H2,1H3/t21?,24?,25-/m0/s1	NNCBRNWEQFDWOJ-MTQWGCILSA-N	590248	US11560385, Compound 24B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590248&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290539	479268812							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247358	Cc1c(cc(CC2CCS(=O)(=O)CC2)n1-c1ccc(Cl)cc1)C(=O)CN1C2CCC1CC2	InChI=1S/C25H31ClN2O3S/c1-17-24(25(29)16-27-20-6-7-21(27)9-8-20)15-23(14-18-10-12-32(30,31)13-11-18)28(17)22-4-2-19(26)3-5-22/h2-5,15,18,20-21H,6-14,16H2,1H3	OULKKSKRPUNASV-UHFFFAOYSA-N	590249	US11560385, Compound 25B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590249&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386698	479268813							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247359	Cc1c(cc(\C=C/CCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C25H29N3O3S/c1-18-24(25(29)17-27-20-10-11-21(27)13-12-20)15-23(5-3-4-14-32(2,30)31)28(18)22-8-6-19(16-26)7-9-22/h3,5-9,15,20-21H,4,10-14,17H2,1-2H3/b5-3-	LIZJFQAXCGBPLF-HYXAFXHYSA-N	590250	US11560385, Compound 26B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590250&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290615	479268814							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247360	Cc1c(cc(\C=C\Cn2cccn2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H27N5O2/c1-18-23(26(33)17-30-21-9-10-24(30)25(32)15-21)14-22(4-2-12-29-13-3-11-28-29)31(18)20-7-5-19(16-27)6-8-20/h2-8,11,13-14,21,24-25,32H,9-10,12,15,17H2,1H3/b4-2+/t21?,24?,25-/m0/s1	SIFJHXFRQLBGKV-NSUHKDPTSA-N	590251	US11560385, Compound 27B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590251&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156291064	479268815							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247361	Cc1c(cc(CCCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CC3CC1CC(C2)O3	InChI=1S/C27H30N4O2/c1-18-26(27(32)17-30-22-11-24-13-23(30)14-25(12-22)33-24)15-21(5-3-2-4-10-28)31(18)20-8-6-19(16-29)7-9-20/h6-9,15,22-25H,2-5,11-14,17H2,1H3	YZCFZSGLCGFKNV-UHFFFAOYSA-N	590253	US11560385, Compound 28B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590253&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274516	479268817							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247362	Cc1c(cc(CCCCC#N)n1-c1ccc(Cl)cc1)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H28ClN3O2/c1-16-21(24(30)15-27-19-10-11-22(27)23(29)14-19)13-20(5-3-2-4-12-26)28(16)18-8-6-17(25)7-9-18/h6-9,13,19,22-23,29H,2-5,10-11,14-15H2,1H3/t19?,22?,23-/m0/s1	YUNQLWNIVCIYNO-HXJXPZHGSA-N	590254	US11560385, Compound 29B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590254&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290541	479268818							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247363	Cc1c(cc(CCCCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C25H31N3O3S/c1-18-24(25(29)17-27-20-10-11-21(27)13-12-20)15-23(5-3-4-14-32(2,30)31)28(18)22-8-6-19(16-26)7-9-22/h6-9,15,20-21H,3-5,10-14,17H2,1-2H3	FMKUXEKKECLDOU-UHFFFAOYSA-N	590255	US11560385, Compound 30B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590255&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386887	479268819							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247364	Cc1c(cc(CCCCC#N)n1-c1ccc(Cl)cc1)C(=O)CN1C2CCC1CC2	InChI=1S/C24H28ClN3O/c1-17-23(24(29)16-27-19-10-11-20(27)13-12-19)15-22(5-3-2-4-14-26)28(17)21-8-6-18(25)7-9-21/h6-9,15,19-20H,2-5,10-13,16H2,1H3	OKIOHDTXZHDEJY-UHFFFAOYSA-N	590256	US11560385, Compound 31B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590256&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386809	479268820							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247365	Cc1c(\C=C\CCS(C)(=O)=O)n(c(C)c1C(=O)CN1C2CCC1CC2)-c1ccc(cc1)C#N	InChI=1S/C26H31N3O3S/c1-18-24(6-4-5-15-33(3,31)32)29(23-9-7-20(16-27)8-10-23)19(2)26(18)25(30)17-28-21-11-12-22(28)14-13-21/h4,6-10,21-22H,5,11-15,17H2,1-3H3/b6-4+	LGMUNGZONVSDEM-GQCTYLIASA-N	590258	US11560385, Compound 32B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590258&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386891	479268822							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247366	Cc1c(C#N)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H22N4O2/c1-13-18(11-24)22(14(2)26(13)16-5-3-15(10-23)4-6-16)21(28)12-25-17-7-8-19(25)20(27)9-17/h3-6,17,19-20,27H,7-9,12H2,1-2H3/t17?,19?,20-/m0/s1	KXBSELPNVWQCTM-UUKMXZOPSA-N	590259	US11560385, Compound 33B::US11560385, Compound 95B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590259&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290667	479268823							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247367	Cc1c(cc(\C=C\CCS(C)(=O)=O)n1-c1ccc(Cl)cc1)C(=O)CN1C2CCC1CC2	InChI=1S/C24H29ClN2O3S/c1-17-23(24(28)16-26-19-10-11-20(26)13-12-19)15-22(5-3-4-14-31(2,29)30)27(17)21-8-6-18(25)7-9-21/h3,5-9,15,19-20H,4,10-14,16H2,1-2H3/b5-3+	OMNOIOMAAGDBHI-HWKANZROSA-N	590261	US11560385, Compound 34B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590261&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386901	479268825							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247368	Cc1c(cc(\C=C\CCS(C)(=O)=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C25H29N3O3S/c1-18-24(25(29)17-27-20-10-11-21(27)13-12-20)15-23(5-3-4-14-32(2,30)31)28(18)22-8-6-19(16-26)7-9-22/h3,5-9,15,20-21H,4,10-14,17H2,1-2H3/b5-3+	LIZJFQAXCGBPLF-HWKANZROSA-N	590262	US11560385, Compound 35B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590262&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274495	479268826							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247369	CSCCCCc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O2S/c1-17-22(25(30)16-27-20-10-11-23(27)24(29)14-20)13-21(5-3-4-12-31-2)28(17)19-8-6-18(15-26)7-9-19/h6-9,13,20,23-24,29H,3-5,10-12,14,16H2,1-2H3/t20?,23?,24-/m0/s1	SOSYGZQHHCWVDC-BOYUCYPVSA-N	590263	US11560385, Compound 37B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590263&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290626	479268827							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247370	CSCCCCCc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C26H33N3O2S/c1-18-23(26(31)17-28-21-11-12-24(28)25(30)15-21)14-22(6-4-3-5-13-32-2)29(18)20-9-7-19(16-27)8-10-20/h7-10,14,21,24-25,30H,3-6,11-13,15,17H2,1-2H3/t21?,24?,25-/m0/s1	YLRGBQUTLFSZBU-MTQWGCILSA-N	590265	US11560385, Compound 38B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590265&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290665	479268829							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247371	Cc1c(cc(CC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H27N3O3/c1-15-21(24(29)12-26-19-6-7-22(26)23(28)10-19)9-20(8-17-13-30-14-17)27(15)18-4-2-16(11-25)3-5-18/h2-5,9,17,19,22-23,28H,6-8,10,12-14H2,1H3/t19?,22?,23-/m0/s1	XPEDMACEKSDWTN-HXJXPZHGSA-N	590266	US11560385, Compound 39B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590266&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290639	479268830							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247372	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c(Cl)c(CCCCC#N)n1-c1ccc(C#N)c(F)c1	InChI=1S/C25H26ClFN4O2/c1-15-24(23(33)14-30-17-8-9-20(30)22(32)12-17)25(26)21(5-3-2-4-10-28)31(15)18-7-6-16(13-29)19(27)11-18/h6-7,11,17,20,22,32H,2-5,8-9,12,14H2,1H3/t17?,20?,22-/m0/s1	ZBILTSCBENMGDS-QVHXHXEWSA-N	590267	US11560385, Compound 40B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590267&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290595	479268831							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247373	Cc1nc(Cc2cc(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1	InChI=1S/C25H26N4O2S/c1-15-22(25(31)13-28-20-7-8-23(28)24(30)11-20)10-21(9-18-14-32-16(2)27-18)29(15)19-5-3-17(12-26)4-6-19/h3-6,10,14,20,23-24,30H,7-9,11,13H2,1-2H3/t20?,23?,24-/m0/s1	AFEUWWJBOJPXLH-BOYUCYPVSA-N	590268	US11560385, Compound 41B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590268&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290538	479268832							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247374	Cc1c(cc(CCCC2(C)COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C27H33N3O3/c1-18-23(26(32)15-29-21-9-10-24(29)25(31)13-21)12-22(4-3-11-27(2)16-33-17-27)30(18)20-7-5-19(14-28)6-8-20/h5-8,12,21,24-25,31H,3-4,9-11,13,15-17H2,1-2H3/t21?,24?,25-/m0/s1	XUEAROZAQWFCDH-MTQWGCILSA-N	590269	US11560385, Compound 42B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590269&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			149287396	479268833							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247375	Cc1c(cc(CCC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H29N3O3/c1-16-22(25(30)13-27-20-8-9-23(27)24(29)11-20)10-21(7-4-18-14-31-15-18)28(16)19-5-2-17(12-26)3-6-19/h2-3,5-6,10,18,20,23-24,29H,4,7-9,11,13-15H2,1H3/t20?,23?,24-/m0/s1	CKFDOZIXBVESBA-BOYUCYPVSA-N	590270	US11560385, Compound 43B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590270&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290569	479268834							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247376	Cc1c(cc(CC2CCOCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H31N3O3/c1-17-23(26(31)16-28-21-6-7-24(28)25(30)14-21)13-22(12-18-8-10-32-11-9-18)29(17)20-4-2-19(15-27)3-5-20/h2-5,13,18,21,24-25,30H,6-12,14,16H2,1H3/t21?,24?,25-/m0/s1	BHJVGUXNEIMNQO-MTQWGCILSA-N	590271	US11560385, Compound 44B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590271&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290562	479268835							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247377	Cc1c(cc(C[C@H]2C[C@@H](C2)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H28N4O2/c1-16-23(26(32)15-29-21-6-7-24(29)25(31)12-21)11-22(10-18-8-19(9-18)14-28)30(16)20-4-2-17(13-27)3-5-20/h2-5,11,18-19,21,24-25,31H,6-10,12,15H2,1H3/t18-,19-,21?,24?,25-/m0/s1	UOSHLWUFYYVZCT-JRDQRXRUSA-N	590272	US11560385, Compound 45B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590272&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			152951067	479268836							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247378	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c(Cl)c(\C=C\CC(C)(C)C#N)n1-c1ccc(cc1)C#N	InChI=1S/C27H29ClN4O2/c1-17-25(24(34)15-31-20-10-11-21(31)23(33)13-20)26(28)22(5-4-12-27(2,3)16-30)32(17)19-8-6-18(14-29)7-9-19/h4-9,20-21,23,33H,10-13,15H2,1-3H3/b5-4+/t20?,21?,23-/m0/s1	FWMHVJGCZOLPOH-CVYDVCASSA-N	590273	US11560385, Compound 46B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590273&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290642	479268837							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247379	Cc1c(cc(C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C21H20N4O2/c1-13-18(21(27)12-24-16-6-7-19(24)20(26)9-16)8-17(11-23)25(13)15-4-2-14(10-22)3-5-15/h2-5,8,16,19-20,26H,6-7,9,12H2,1H3/t16?,19?,20-/m0/s1	FQKVAENMCLVQKN-GQOXECLESA-N	590274	US11560385, Compound 47B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590274&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290650	479268838							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247380	Cc1c(cc(CC[Si](C)(C)C)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H33N3O2Si/c1-17-22(25(30)16-27-20-9-10-23(27)24(29)14-20)13-21(11-12-31(2,3)4)28(17)19-7-5-18(15-26)6-8-19/h5-8,13,20,23-24,29H,9-12,14,16H2,1-4H3/t20?,23?,24-/m0/s1	QYQYUASIRSBDTH-BOYUCYPVSA-N	590275	US11560385, Compound 50B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590275&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677925	479268839							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247381	Cc1c(cc(CCCC2CC(C)(C)OC2=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C29H35N3O4/c1-18-24(27(34)17-31-22-11-12-25(31)26(33)14-22)13-23(32(18)21-9-7-19(16-30)8-10-21)6-4-5-20-15-29(2,3)36-28(20)35/h7-10,13,20,22,25-26,33H,4-6,11-12,14-15,17H2,1-3H3/t20?,22?,25?,26-/m0/s1	DXWUXNNSMZSOIH-PFLWBEKGSA-N	590276	US11560385, Compound 51B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590276&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386625	479268840							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247382	Cc1c(cc(\C=C\CC2CC(C)(C)OC2=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C29H33N3O4/c1-18-24(27(34)17-31-22-11-12-25(31)26(33)14-22)13-23(32(18)21-9-7-19(16-30)8-10-21)6-4-5-20-15-29(2,3)36-28(20)35/h4,6-10,13,20,22,25-26,33H,5,11-12,14-15,17H2,1-3H3/b6-4+/t20?,22?,25?,26-/m0/s1	SZYNUVWSQMDPLO-GCRIGCQPSA-N	590277	US11560385, Compound 52B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590277&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386656	479268841							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247383	C[C@H]1CC2CCC1N2CC(=O)c1cc(CC2COC2)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C25H29N3O2/c1-16-9-21-7-8-24(16)27(21)13-25(29)23-11-22(10-19-14-30-15-19)28(17(23)2)20-5-3-18(12-26)4-6-20/h3-6,11,16,19,21,24H,7-10,13-15H2,1-2H3/t16-,21?,24?/m0/s1	UFKSLTUGDANWMZ-FERLNZQHSA-N	590278	US11560385, Compound 53B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590278&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290695	479268842							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247384	Cc1c(cc(CC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1CC2	InChI=1S/C24H27N3O2/c1-16-23(24(28)13-26-19-6-7-20(26)9-8-19)11-22(10-18-14-29-15-18)27(16)21-4-2-17(12-25)3-5-21/h2-5,11,18-20H,6-10,13-15H2,1H3	FOJHQFQPMYKECZ-UHFFFAOYSA-N	590279	US11560385, Compound 54B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590279&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274710	479268843							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247385	Cc1c(cc(CCC2(C)COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H31N3O3/c1-17-22(25(31)14-28-20-7-8-23(28)24(30)12-20)11-21(9-10-26(2)15-32-16-26)29(17)19-5-3-18(13-27)4-6-19/h3-6,11,20,23-24,30H,7-10,12,14-16H2,1-2H3/t20?,23?,24-/m0/s1	AKTJKCOIIUQJHB-BOYUCYPVSA-N	590280	US11560385, Compound 55B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590280&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290614	479268844							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247386	C[C@H]1CC2CCC1N2CC(=O)c1cc(CC2COC2)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C25H29N3O2/c1-16-9-21-7-8-24(16)27(21)13-25(29)23-11-22(10-19-14-30-15-19)28(17(23)2)20-5-3-18(12-26)4-6-20/h3-6,11,16,19,21,24H,7-10,13-15H2,1-2H3/t16-,21?,24?/m0/s1	UFKSLTUGDANWMZ-FERLNZQHSA-N	590281	US11560385, Compound 56B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590281&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290695	479268845							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247387	Cc1c(cc(C#CC2COC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H25N3O3/c1-16-22(25(30)13-27-20-8-9-23(27)24(29)11-20)10-21(7-4-18-14-31-15-18)28(16)19-5-2-17(12-26)3-6-19/h2-3,5-6,10,18,20,23-24,29H,8-9,11,13-15H2,1H3/t20?,23?,24-/m0/s1	MSEHVENNAOJFHN-BOYUCYPVSA-N	590282	US11560385, Compound 57B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590282&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290647	479268846							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247388	Cc1cc(C(=O)CN2C3CCC2CC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C21H23N3O/c1-14-11-20(21(25)13-23-17-7-8-18(23)10-9-17)15(2)24(14)19-5-3-16(12-22)4-6-19/h3-6,11,17-18H,7-10,13H2,1-2H3	FQBBXLHIXBVPAT-UHFFFAOYSA-N	590283	US11560385, Compound 63B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590283&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386768	479268847							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247389	Cc1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C21H23N3O2/c1-13-9-18(14(2)24(13)16-5-3-15(11-22)4-6-16)21(26)12-23-17-7-8-19(23)20(25)10-17/h3-6,9,17,19-20,25H,7-8,10,12H2,1-2H3/t17?,19?,20-/m0/s1	NECNLMQUOLCSTD-UUKMXZOPSA-N	590284	US11560385, Compound 64B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590284&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386466	479268848							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247390	Cc1cc(C(=O)CN2[C@@H]3CC[C@@H]2CC(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-9-21(15(2)25(14)17-5-3-16(12-23)4-6-17)22(27)13-24-18-7-8-19(24)11-20(26)10-18/h3-6,9,18-20,26H,7-8,10-11,13H2,1-2H3/t18-,19-/m1/s1	QKFBBSVWQLGGHF-RTBURBONSA-N	590285	US11560385, Compound 66B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590285&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290532	479268849							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247391	Cc1cc(C(=O)CN2[C@@H]3CC[C@@H]2CC(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-9-21(15(2)25(14)17-5-3-16(12-23)4-6-17)22(27)13-24-18-7-8-19(24)11-20(26)10-18/h3-6,9,18-20,26H,7-8,10-11,13H2,1-2H3/t18-,19-/m1/s1	QKFBBSVWQLGGHF-RTBURBONSA-N	590286	US11560385, Compound 67B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590286&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290532	479268850							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247392	Cc1cc(C(=O)CN2[C@@H]3CC[C@@H]2CC(C)(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-10-21(16(2)26(15)18-6-4-17(13-24)5-7-18)22(27)14-25-19-8-9-20(25)12-23(3,28)11-19/h4-7,10,19-20,28H,8-9,11-12,14H2,1-3H3/t19-,20-/m1/s1	TUNVOPVEZGTPGK-WOJBJXKFSA-N	590287	US11560385, Compound 68B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590287&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156677910	479268851							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247393	Cc1cc(C(=O)CN2C3CCC2CCC3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O/c1-15-12-21(16(2)25(15)20-8-6-17(13-23)7-9-20)22(26)14-24-18-4-3-5-19(24)11-10-18/h6-9,12,18-19H,3-5,10-11,14H2,1-2H3	OYRANNNUFJKOTD-UHFFFAOYSA-N	590288	US11560385, Compound 69B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590288&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290680	479268852							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247394	CO[C@H]1CC2CCC1N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-10-19(15(2)25(14)17-6-4-16(12-23)5-7-17)21(26)13-24-18-8-9-20(24)22(11-18)27-3/h4-7,10,18,20,22H,8-9,11,13H2,1-3H3/t18?,20?,22-/m0/s1	HBIPPZSXFLNFIV-ZNIKRAEXSA-N	590289	US11560385, Compound 70B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590289&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290679	479268853							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247395	Cc1cc(C(=O)CN2C3CCC2[C@@](C)(O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-14-10-19(15(2)25(14)17-6-4-16(12-23)5-7-17)20(26)13-24-18-8-9-21(24)22(3,27)11-18/h4-7,10,18,21,27H,8-9,11,13H2,1-3H3/t18?,21?,22-/m0/s1	RHYISKFFDMHRBV-UDJZJCJKSA-N	590290	US11560385, Compound 71B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590290&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386804	479268854							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247396	Cc1cc(C(=O)CN2C3CCC2[C@@](O)(C3)C(C)(C)C)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O2/c1-16-12-21(17(2)28(16)19-8-6-18(14-26)7-9-19)22(29)15-27-20-10-11-23(27)25(30,13-20)24(3,4)5/h6-9,12,20,23,30H,10-11,13,15H2,1-5H3/t20?,23?,25-/m0/s1	IINKWCYYHHFJBH-QNAFOZIXSA-N	590291	US11560385, Compound 72B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590291&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			153386572	479268855							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247397	Cc1cc(C(=O)CN2C3CCC2[C@@](O)(C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H22F3N3O2/c1-13-9-18(14(2)28(13)16-5-3-15(11-26)4-6-16)19(29)12-27-17-7-8-20(27)21(30,10-17)22(23,24)25/h3-6,9,17,20,30H,7-8,10,12H2,1-2H3/t17?,20?,21-/m0/s1	IKNDQLDFRTWQLH-JITJBCMDSA-N	590292	US11560385, Compound 73B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590292&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290635	479268856							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247398	Cc1cc(C(=O)CN2[C@@H]3CC[C@@H]2CC(O)(C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H24F3N3O2/c1-14-9-20(15(2)29(14)17-5-3-16(12-27)4-6-17)21(30)13-28-18-7-8-19(28)11-22(31,10-18)23(24,25)26/h3-6,9,18-19,31H,7-8,10-11,13H2,1-2H3/t18-,19-/m1/s1	OPIRLWRJAXDHJP-RTBURBONSA-N	590293	US11560385, Compound 74B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590293&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290693	479268857							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247399	Cc1cc(C(=O)CN2[C@@H]3CC[C@@H]2CC(O)(C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C23H24F3N3O2/c1-14-9-20(15(2)29(14)17-5-3-16(12-27)4-6-17)21(30)13-28-18-7-8-19(28)11-22(31,10-18)23(24,25)26/h3-6,9,18-19,31H,7-8,10-11,13H2,1-2H3/t18-,19-/m1/s1	OPIRLWRJAXDHJP-RTBURBONSA-N	590294	US11560385, Compound 75B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590294&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290693	479268858							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247400	Cc1c(C)n(c(C)c1C(=O)CN1C2CCC1[C@@H](O)C2)-c1ccc(cc1)C#N	InChI=1S/C22H25N3O2/c1-13-14(2)25(17-6-4-16(11-23)5-7-17)15(3)22(13)21(27)12-24-18-8-9-19(24)20(26)10-18/h4-7,18-20,26H,8-10,12H2,1-3H3/t18?,19?,20-/m0/s1	WZIOVDYTXGISRV-MHJFOBGBSA-N	590295	US11560385, Compound 76B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590295&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290544	479268859							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247401	Cc1c(Cl)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C21H22ClN3O2/c1-12-20(19(27)11-24-16-7-8-17(24)18(26)9-16)21(22)13(2)25(12)15-5-3-14(10-23)4-6-15/h3-6,16-18,26H,7-9,11H2,1-2H3/t16?,17?,18-/m0/s1	OTFLYXABXJIFJC-ABHNRTSZSA-N	590296	US11560385, Compound 77B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590296&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290555	479268860							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247402	Cc1c(F)c(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C21H22FN3O2/c1-12-20(19(27)11-24-16-7-8-17(24)18(26)9-16)21(22)13(2)25(12)15-5-3-14(10-23)4-6-15/h3-6,16-18,26H,7-9,11H2,1-2H3/t16?,17?,18-/m0/s1	QGGWJWPNYCEPEL-ABHNRTSZSA-N	590297	US11560385, Compound 78B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590297&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290675	479268861							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247403	Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c(c(C)n1-c1ccc(cc1)C#N)C(C)(F)F	InChI=1S/C23H25F2N3O2/c1-13-21(20(30)12-27-17-8-9-18(27)19(29)10-17)22(23(3,24)25)14(2)28(13)16-6-4-15(11-26)5-7-16/h4-7,17-19,29H,8-10,12H2,1-3H3/t17?,18?,19-/m0/s1	YZJDYLCMCGVXKD-ACBHZAAOSA-N	590298	US11560385, Compound 79B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590298&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290765	479268862							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247404	Cc1cc(C(=O)CN2C3CC4CC(C3)CC2C4)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H27N3O/c1-15-7-23(16(2)27(15)20-5-3-17(13-25)4-6-20)24(28)14-26-21-9-18-8-19(11-21)12-22(26)10-18/h3-7,18-19,21-22H,8-12,14H2,1-2H3	GIHVWAMPLBJZPO-UHFFFAOYSA-N	590299	US11560385, Compound 80B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590299&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156274712	479268863							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247465	CC(O)C12CCC(CC1)N2CC(=O)c1cc(C)n(c1C)-c1ccc(cc1)C#N	InChI=1S/C23H27N3O2/c1-15-12-21(16(2)26(15)20-6-4-18(13-24)5-7-20)22(28)14-25-19-8-10-23(25,11-9-19)17(3)27/h4-7,12,17,19,27H,8-11,14H2,1-3H3	YAPBCTYMHISZFY-UHFFFAOYSA-N	590702	US11560385, Compound 143B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590702&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290593	479268924							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247466	Cc1nc(cs1)-c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H24N4O2S/c1-14-19(24(30)12-27-18-7-8-21(27)23(29)9-18)10-22(20-13-31-15(2)26-20)28(14)17-5-3-16(11-25)4-6-17/h3-6,10,13,18,21,23,29H,7-9,12H2,1-2H3/t18?,21?,23-/m0/s1	BXOQKGNLWBSYGO-HCPAQRILSA-N	590703	US11560385, Compound 144B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590703&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290681	479268925							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247467	Cc1c(cc(-c2csc(n2)C(F)(F)F)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H21F3N4O2S/c1-13-17(22(33)11-30-16-6-7-19(30)21(32)8-16)9-20(18-12-34-23(29-18)24(25,26)27)31(13)15-4-2-14(10-28)3-5-15/h2-5,9,12,16,19,21,32H,6-8,11H2,1H3/t16?,19?,21-/m0/s1	NNTATUXLULTMRI-IOYBJCICSA-N	590704	US11560385, Compound 145B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590704&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290682	479268926							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247468	Cc1c(cc(-c2nccs2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C23H22N4O2S/c1-14-18(22(29)13-26-17-6-7-19(26)21(28)10-17)11-20(23-25-8-9-30-23)27(14)16-4-2-15(12-24)3-5-16/h2-5,8-9,11,17,19,21,28H,6-7,10,13H2,1H3/t17?,19?,21-/m0/s1	QYODJUZJLBHSCZ-XTXLOEGASA-N	590705	US11560385, Compound 146B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590705&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290643	479268927							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247469	Cc1ncc(s1)-c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C24H24N4O2S/c1-14-19(23(30)13-27-18-7-8-20(27)22(29)9-18)10-21(24-12-26-15(2)31-24)28(14)17-5-3-16(11-25)4-6-17/h3-6,10,12,18,20,22,29H,7-9,13H2,1-2H3/t18?,20?,22-/m0/s1	OODUHKBKQNPCIE-ZNIKRAEXSA-N	590706	US11560385, Compound 147B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590706&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156291077	479268928							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247470	Cc1cc(C(=O)CN2C3CCC2[C@@H](CC(C)(C)O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C25H31N3O2/c1-16-11-22(17(2)28(16)20-7-5-18(14-26)6-8-20)24(29)15-27-21-9-10-23(27)19(12-21)13-25(3,4)30/h5-8,11,19,21,23,30H,9-10,12-13,15H2,1-4H3/t19-,21?,23?/m1/s1	JJWQWBSHXYDCIR-VWRAKTAISA-N	590707	US11560385, Compound 148B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590707&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290632	479268929							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247471	Cc1c(F)c(C(=O)CN2C3CCC2C(=C3)C(F)(F)F)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C22H19F4N3O/c1-12-20(21(23)13(2)29(12)15-5-3-14(10-27)4-6-15)19(30)11-28-16-7-8-18(28)17(9-16)22(24,25)26/h3-6,9,16,18H,7-8,11H2,1-2H3	IHLWUFKOECDBJB-UHFFFAOYSA-N	590708	US11560385, Compound 149B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590708&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147918134	479268930							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247472	C[C@@H](C1CCC1)c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C26H31N3O2/c1-16(19-4-3-5-19)24-13-22(17(2)29(24)20-8-6-18(14-27)7-9-20)26(31)15-28-21-10-11-23(28)25(30)12-21/h6-9,13,16,19,21,23,25,30H,3-5,10-12,15H2,1-2H3/t16-,21?,23?,25-/m0/s1	VKSBMNUHAZFWQZ-PVVBHEMZSA-N	590709	US11560385, Compound 150B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590709&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290579	479268931							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247473	C[C@H](C1CCC1)c1cc(C(=O)CN2C3CCC2[C@@H](O)C3)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C26H31N3O2/c1-16(19-4-3-5-19)24-13-22(17(2)29(24)20-8-6-18(14-27)7-9-20)26(31)15-28-21-10-11-23(28)25(30)12-21/h6-9,13,16,19,21,23,25,30H,3-5,10-12,15H2,1-2H3/t16-,21?,23?,25+/m1/s1	VKSBMNUHAZFWQZ-GJUDNMQLSA-N	590710	US11560385, Compound 151B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590710&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290692	479268932							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247474	Cc1c(cc(\C=C\CN2C(=O)c3ccccc3C2=O)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C31H28N4O4/c1-19-26(29(37)18-34-22-12-13-27(34)28(36)16-22)15-23(35(19)21-10-8-20(17-32)9-11-21)5-4-14-33-30(38)24-6-2-3-7-25(24)31(33)39/h2-11,15,22,27-28,36H,12-14,16,18H2,1H3/b5-4+/t22?,27?,28-/m0/s1	FMBTVPJXAJGBGP-RXNSBXKKSA-N	590711	US11560385, Compound 153B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590711&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			147525843	479268933							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247475	Cc1c(cc(CCCOC(F)(F)F)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C24H26F3N3O3/c1-15-20(23(32)14-29-18-8-9-21(29)22(31)12-18)11-19(3-2-10-33-24(25,26)27)30(15)17-6-4-16(13-28)5-7-17/h4-7,11,18,21-22,31H,2-3,8-10,12,14H2,1H3/t18?,21?,22-/m0/s1	IXUBHGGQAQBXNO-UDJZJCJKSA-N	590712	US11560385, Compound 155B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590712&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290823	479268934							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247476	Cc1c(cc(\C=C\CN)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C23H26N4O2/c1-15-20(23(29)14-26-18-8-9-21(26)22(28)12-18)11-19(3-2-10-24)27(15)17-6-4-16(13-25)5-7-17/h2-7,11,18,21-22,28H,8-10,12,14,24H2,1H3/b3-2+/t18?,21?,22-/m0/s1	FVFKNYGFGZDCPE-MVOSBBFYSA-N	590713	US11560385, Compound 156B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		<50							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590713&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290775	479268935							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247477	Cc1c(cc(CC2(Cl)CCC2)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C25H28ClN3O2/c1-16-21(24(31)15-28-19-7-8-22(28)23(30)12-19)11-20(13-25(26)9-2-10-25)29(16)18-5-3-17(14-27)4-6-18/h3-6,11,19,22-23,30H,2,7-10,12-13,15H2,1H3/t19?,22?,23-/m0/s1	GEMGFVQCBVLHMD-HXJXPZHGSA-N	590714	US11560385, Compound 157B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 275							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590714&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290584	479268936							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
1247478	Cc1c(cc(CC23CC(C2)C3)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2	InChI=1S/C26H29N3O2/c1-16-22(25(31)15-28-20-6-7-23(28)24(30)9-20)8-21(13-26-10-18(11-26)12-26)29(16)19-4-2-17(14-27)3-5-19/h2-5,8,18,20,23-24,30H,6-7,9-13,15H2,1H3/t18?,20?,23?,24-,26?/m0/s1	ACDYXBCCRUMFPS-QAWDVHMMSA-N	590715	US11560385, Compound 158B	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		>500							US Patent		10.7270/Q2445RDM			US11560385	Cullen, M; Bastos, CM; Parks, D; Munoz, B	Proteostasis Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=590715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=590715&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			156290567	479268937							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51511631	Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1	InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3	JUWDSDKJBMFLHE-UHFFFAOYSA-N	50437694	CHEMBL1410015	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 12250							ChEMBL		10.7270/Q2BV7MVN	32092586			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437694&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	IU1	6IIK	675434	175450011		CHEMBL1410015				ZINC00038235	1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51511632	Cc1cc(C(=O)CN2CCCCC2)c(C)n1-c1ccc(F)cc1	InChI=1S/C19H23FN2O/c1-14-12-18(19(23)13-21-10-4-3-5-11-21)15(2)22(14)17-8-6-16(20)7-9-17/h6-9,12H,3-5,10-11,13H2,1-2H3	RYIVINSSPOAIBA-UHFFFAOYSA-N	50608541	CHEMBL1493046	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 680							ChEMBL		10.7270/Q2BV7MVN	32092586			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608541&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			675432	494498289							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51511633	Cc1cc(C(=O)CN2CCC(O)CC2)c(C)n1-c1ccc(cc1)C#N	InChI=1S/C20H23N3O2/c1-14-11-19(20(25)13-22-9-7-18(24)8-10-22)15(2)23(14)17-5-3-16(12-21)4-6-17/h3-6,11,18,24H,7-10,13H2,1-2H3	WFOUOZGIXDMUJU-UHFFFAOYSA-N	50608542	CHEMBL5276142	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens		 830							ChEMBL		10.7270/Q2BV7MVN	32092586			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608542&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			135393505	494498290							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5						
51511638	[O-][N+](=O)c1cc(\C=C2/CCN(C\C(=C/c3ccc(F)c(c3)[N+]([O-])=O)C2=O)C(=O)C=C)ccc1F	InChI=1S/C23H17F2N3O6/c1-2-22(29)26-8-7-16(9-14-3-5-18(24)20(11-14)27(31)32)23(30)17(13-26)10-15-4-6-19(25)21(12-15)28(33)34/h2-6,9-12H,1,7-8,13H2/b16-9+,17-10+	SCKXBVLYWLLALY-CZCYGEDCSA-N	50608543	CHEMBL4441423	Ubiquitin carboxyl-terminal hydrolase 14	Homo sapiens			 14000						ChEMBL		10.7270/Q2BV7MVN	32092586			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006409&target=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608543&enzyme=Ubiquitin+carboxyl-terminal+hydrolase+14&column=ki&startPg=0&Increment=50&submit=Search			71523377	494498291							1	MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ	2AYN,2AYO,5GJQ,6IIK,6IIL,6IIM,6IIN,7W37,7W38,7W39,7W3A,7W3B,7W3C,7W3F,7W3G,7W3H,7W3I,7W3J,7W3K,7W3M	Ubiquitin carboxyl-terminal hydrolase 14	UBP14_HUMAN	P54578	B7Z4N8 J3QRZ5 Q53XY5