BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51058438 COCCNc1nc(OCCc2ccc(OC)cc2)c2c(n1)-c1ccccc1CC2(C)C InChI=1S/C26H31N3O3/c1-26(2)17-19-7-5-6-8-21(19)23-22(26)24(29-25(28-23)27-14-16-30-3)32-15-13-18-9-11-20(31-4)12-10-18/h5-12H,13-17H2,1-4H3,(H,27,28,29) IDWGLPWUGWIJJK-UHFFFAOYSA-N 50431665 CHEMBL2349388 Streptokinase Streptococcus pyogenes 5500 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431665&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71718999 164160540 CHEMBL2349388 ZINC95601468 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058439 CCNc1nc2-c3ccc(OC(C)C)cc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C22H29N3O2/c1-7-11-25-20(26)18-19(24-21(25)23-8-2)17-10-9-16(27-14(3)4)12-15(17)13-22(18,5)6/h7,9-10,12,14H,1,8,11,13H2,2-6H3,(H,23,24) ORASQFNHQMTSJS-UHFFFAOYSA-N 50431666 CHEMBL2349398 Streptokinase Streptococcus pyogenes 4100 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431666&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71716560 164160541 CHEMBL2349398 ZINC95605637 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058440 COc1ccc-2c(CC(C)(C)c3c-2nc(NCC=C)n(CC=C)c3=O)c1 InChI=1S/C21H25N3O2/c1-6-10-22-20-23-18-16-9-8-15(26-5)12-14(16)13-21(3,4)17(18)19(25)24(20)11-7-2/h6-9,12H,1-2,10-11,13H2,3-5H3,(H,22,23) HCVDILILUCAWLD-UHFFFAOYSA-N 50431667 CHEMBL2349392 Streptokinase Streptococcus pyogenes 6900 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431667&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71720837 164160542 CHEMBL2349392 ZINC95605818 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058441 CCNc1nc2-c3ccc(OC)cc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C20H25N3O2/c1-6-10-23-18(24)16-17(22-19(23)21-7-2)15-9-8-14(25-5)11-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3,(H,21,22) JZWDIKXEEAIKSF-UHFFFAOYSA-N 50431668 CCG-203592 Streptokinase Streptococcus pyogenes 3100 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431668&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71716565 164160543 ZINC95601452 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058442 CCNc1nc2-c3cc(OC)ccc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C20H25N3O2/c1-6-10-23-18(24)16-17(22-19(23)21-7-2)15-11-14(25-5)9-8-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3,(H,21,22) SBPYBUKCNWFXCZ-UHFFFAOYSA-N 50431669 CHEMBL2349512 Streptokinase Streptococcus pyogenes 1300 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431669&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71720202 164160544 CHEMBL2349512 ZINC95604487 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058443 CCSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C19H22N2OS/c1-5-11-21-17(22)15-16(20-18(21)23-6-2)14-10-8-7-9-13(14)12-19(15,3)4/h5,7-10H,1,6,11-12H2,2-4H3 GZVLJDIHXGMETB-UHFFFAOYSA-N 50431670 CHEMBL2349510 Streptokinase Streptococcus pyogenes 2000 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431670&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 903534 164160545 CHEMBL2349510 ZINC00483764 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058444 CC1(C)Cc2ccccc2-c2nc(SCc3ccccc3)n(CC=C)c(=O)c12 InChI=1S/C24H24N2OS/c1-4-14-26-22(27)20-21(19-13-9-8-12-18(19)15-24(20,2)3)25-23(26)28-16-17-10-6-5-7-11-17/h4-13H,1,14-16H2,2-3H3 JILNCQRSXPRIOQ-UHFFFAOYSA-N 50431671 CHEMBL2349509 Streptokinase Streptococcus pyogenes 10800 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431671&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 1982569 164160546 CHEMBL2349509 ZINC02372320 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058445 COCCSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C20H24N2O2S/c1-5-10-22-18(23)16-17(21-19(22)25-12-11-24-4)15-9-7-6-8-14(15)13-20(16,2)3/h5-9H,1,10-13H2,2-4H3 CUQYUVFMCIQXEP-UHFFFAOYSA-N 50431672 CHEMBL2349411 Streptokinase Streptococcus pyogenes 3200 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431672&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 46871603 164160547 CHEMBL2349411 ZINC95604694 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058446 CSc1nc2-c3ccccc3CC3(CCCCC3)c2c(=O)n1CC=C InChI=1S/C21H24N2OS/c1-3-13-23-19(24)17-18(22-20(23)25-2)16-10-6-5-9-15(16)14-21(17)11-7-4-8-12-21/h3,5-6,9-10H,1,4,7-8,11-14H2,2H3 QKANIKDMGKRHLS-UHFFFAOYSA-N 50431673 CHEMBL2349522 Streptokinase Streptococcus pyogenes 19000 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431673&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 1068691 164160548 CHEMBL2349522 ZINC00753649 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058447 C=CCn1c(SCc2ccccc2)nc2-c3ccccc3CC3(CCCCC3)c2c1=O InChI=1S/C27H28N2OS/c1-2-17-29-25(30)23-24(28-26(29)31-19-20-11-5-3-6-12-20)22-14-8-7-13-21(22)18-27(23)15-9-4-10-16-27/h2-3,5-8,11-14H,1,4,9-10,15-19H2 KSEGLGJSSBNJML-UHFFFAOYSA-N 50431674 CCG-102487 Streptokinase Streptococcus pyogenes >50000 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431674&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 1581910 164160549 ZINC01794885 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51058448 CCCCSc1nc2-c3ccccc3CC3(CCCCC3)c2c(=O)n1CC=C InChI=1S/C24H30N2OS/c1-3-5-16-28-23-25-21-19-12-8-7-11-18(19)17-24(13-9-6-10-14-24)20(21)22(27)26(23)15-4-2/h4,7-8,11-12H,2-3,5-6,9-10,13-17H2,1H3 QPMLYPXHSWZKFJ-UHFFFAOYSA-N 50431675 CCG-2979 Streptokinase Streptococcus pyogenes >50000 ChEMBL 10.1016/j.bmc.2013.01.046 10.7270/Q2862HTW 23433668 Yestrepsky, BD; Xu, Y; Breen, ME; Li, X; Rajeswaran, WG; Ryu, JG; Sorenson, RJ; Tsume, Y; Wilson, MW; Zhang, W; Sun, D; Sun, H; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431675&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 1602323 164160550 ZINC01823371 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51095644 CC1(C)Cc2cc(ccc2-c2nc(SCCOCC#C)n(CC=C)c(=O)c12)C(=O)c1ccccc1 InChI=1S/C29H28N2O3S/c1-5-14-31-27(33)24-25(30-28(31)35-17-16-34-15-6-2)23-13-12-21(18-22(23)19-29(24,3)4)26(32)20-10-8-7-9-11-20/h2,5,7-13,18H,1,14-17,19H2,3-4H3 OTSGOLFDSKLMPN-UHFFFAOYSA-N 50449287 CHEMBL3125353 Streptokinase Streptococcus pyogenes 3800 ChEMBL 10.1016/j.bmcl.2014.01.079 10.7270/Q2959K2G 24559768 Yestrepsky, BD; Kretz, CA; Xu, Y; Holmes, A; Sun, H; Ginsburg, D; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50449287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50449287&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 76314541 194947183 CHEMBL3125353 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51095645 CCSc1nc2-c3cc(OC)ccc3CC(C)(C)c2c(=O)n1CC=C InChI=1S/C20H24N2O2S/c1-6-10-22-18(23)16-17(21-19(22)25-7-2)15-11-14(24-5)9-8-13(15)12-20(16,3)4/h6,8-9,11H,1,7,10,12H2,2-5H3 GYBNUOJEKKWWOJ-UHFFFAOYSA-N 50449288 CHEMBL3125359 Streptokinase Streptococcus pyogenes 1300 ChEMBL 10.1016/j.bmcl.2014.01.079 10.7270/Q2959K2G 24559768 Yestrepsky, BD; Kretz, CA; Xu, Y; Holmes, A; Sun, H; Ginsburg, D; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50449288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50449288&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 71583864 194947184 CHEMBL3125359 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51095646 CC1(CCOc2ccc-3c(CC(C)(C)c4c-3nc(SCCOCC#C)n(CC=C)c4=O)c2)N=N1 InChI=1S/C26H30N4O3S/c1-6-11-30-23(31)21-22(27-24(30)34-15-14-32-12-7-2)20-9-8-19(16-18(20)17-25(21,3)4)33-13-10-26(5)28-29-26/h2,6,8-9,16H,1,10-15,17H2,3-5H3 AYXMCXDILWJSNB-UHFFFAOYSA-N 50449289 CHEMBL3125355 Streptokinase Streptococcus pyogenes 330 ChEMBL 10.1016/j.bmcl.2014.01.079 10.7270/Q2959K2G 24559768 Yestrepsky, BD; Kretz, CA; Xu, Y; Holmes, A; Sun, H; Ginsburg, D; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50449289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50449289&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 76332663 194947185 CHEMBL3125355 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471 51095647 CC1(C)Cc2ccc(cc2-c2nc(SCCOCC#C)n(CC=C)c(=O)c12)N=[N+]=[N-] InChI=1S/C22H23N5O2S/c1-5-9-27-20(28)18-19(24-21(27)30-12-11-29-10-6-2)17-13-16(25-26-23)8-7-15(17)14-22(18,3)4/h2,5,7-8,13H,1,9-12,14H2,3-4H3 YYLJUVJJIVUREP-UHFFFAOYSA-N 50449290 CHEMBL3125358 Streptokinase Streptococcus pyogenes 190 ChEMBL 10.1016/j.bmcl.2014.01.079 10.7270/Q2959K2G 24559768 Yestrepsky, BD; Kretz, CA; Xu, Y; Holmes, A; Sun, H; Ginsburg, D; Larsen, SD University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50449290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006367&target=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50449290&enzyme=Streptokinase&column=ki&startPg=0&Increment=50&submit=Search 76314542 194947186 CHEMBL3125358 1 MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLGRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLRPKSKPLATDKGAMSHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQEFLLSGHVRVRPYRPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGDSLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKTGIEEKTNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTIKYVDVDTKALLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMGYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRDTGTPIPDNPKDK Streptokinase STRQ_STRPY P96471