BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
51039688	Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3I)c12)C(=O)c1ccc(Cl)cc1	InChI=1S/C21H12ClIN4OS/c22-11-7-5-10(6-8-11)18(28)19-17(25)16-15(12-3-1-2-4-14(12)23)13(9-24)20(26)27-21(16)29-19/h1-8H,25H2,(H2,26,27)	BYOCRHHRURIQKE-UHFFFAOYSA-N	50424221	CHEMBL2313821	Glycogen synthase kinase-3	Dictyostelium discoideum		>100000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424221&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			1729742	164153096		CHEMBL2313821				ZINC33355350	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0						
51039689	Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Cl)c12)C(=O)c1cccc(c1)C#N	InChI=1S/C22H12ClN5OS/c23-15-7-2-1-6-13(15)16-14(10-25)21(27)28-22-17(16)18(26)20(30-22)19(29)12-5-3-4-11(8-12)9-24/h1-8H,26H2,(H2,27,28)	UPNKCMLDXIQRRO-UHFFFAOYSA-N	50424222	CHEMBL2314101	Glycogen synthase kinase-3	Dictyostelium discoideum		>100000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424222	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424222&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			51347987	164153097		CHEMBL2314101				ZINC72316646	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0						
51039690	Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Cl)c12)C(=O)c1cccc(Cl)c1	InChI=1S/C21H12Cl2N4OS/c22-11-5-3-4-10(8-11)18(28)19-17(25)16-15(12-6-1-2-7-14(12)23)13(9-24)20(26)27-21(16)29-19/h1-8H,25H2,(H2,26,27)	BXLXOBIMRFZEAE-UHFFFAOYSA-N	50424223	CHEMBL2313853	Glycogen synthase kinase-3	Dictyostelium discoideum		>10000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424223	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424223&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			51039273	164153098		CHEMBL2313853				ZINC72316650	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0						
51039691	Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Br)c12)C(=O)c1cccc(Cl)c1	InChI=1S/C21H12BrClN4OS/c22-14-7-2-1-6-12(14)15-13(9-24)20(26)27-21-16(15)17(25)19(29-21)18(28)10-4-3-5-11(23)8-10/h1-8H,25H2,(H2,26,27)	JQGHYQLEGOHXLL-UHFFFAOYSA-N	50424224	CHEMBL2313850	Glycogen synthase kinase-3	Dictyostelium discoideum		 80000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424224&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			51347839	164153099		CHEMBL2313850				ZINC72316649	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0						
51039692	Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3I)c12)C(=O)c1cccc(Cl)c1	InChI=1S/C21H12ClIN4OS/c22-11-5-3-4-10(8-11)18(28)19-17(25)16-15(12-6-1-2-7-14(12)23)13(9-24)20(26)27-21(16)29-19/h1-8H,25H2,(H2,26,27)	ZVOBNYHMHINOQM-UHFFFAOYSA-N	50424225	CHEMBL2313844	Glycogen synthase kinase-3	Dictyostelium discoideum		>100000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424225&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			51347682	164153100		CHEMBL2313844				ZINC72316648	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0						
51039693	COc1ccccc1-c1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12	InChI=1S/C22H16N4O2S/c1-28-15-10-6-5-9-13(15)16-14(11-23)21(25)26-22-17(16)18(24)20(29-22)19(27)12-7-3-2-4-8-12/h2-10H,24H2,1H3,(H2,25,26)	VZKSJRYVKJUBMK-UHFFFAOYSA-N	50424226	CHEMBL2314102	Glycogen synthase kinase-3	Dictyostelium discoideum		>100000							ChEMBL	10.1021/jm301575n	10.7270/Q2251KH3	23214499			Fugel, W; Oberholzer, AE; Gschloessl, B; Dzikowski, R; Pressburger, N; Preu, L; Pearl, LH; Baratte, B; Ratin, M; Okun, I; Doerig, C; Kruggel, S; Lemcke, T; Meijer, L; Kunick, C	Technische Universit£t Braunschweig	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50424226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006321&target=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50424226&enzyme=Glycogen+synthase+kinase-3&column=ki&startPg=0&Increment=50&submit=Search			51347384	164153101		CHEMBL2314102				ZINC72316647	1	MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH		Glycogen synthase kinase-3	GSK3_DICDI	P51136	Q55A28 Q86KY0