BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
50952658	CCCC[C@]1(CC)CS(=O)(=O)c2ccccc2[C@H](N1)c1ccccc1	InChI=1S/C21H27NO2S/c1-3-5-15-21(4-2)16-25(23,24)19-14-10-9-13-18(19)20(22-21)17-11-7-6-8-12-17/h6-14,20,22H,3-5,15-16H2,1-2H3/t20-,21-/m1/s1	RUWCWTXHTOBJIA-NHCUHLMSSA-N	50390996	CHEMBL2074988	Ileal sodium/bile acid cotransporter	Mus musculus	 68								ChEMBL	10.1021/bi0205404	10.7270/Q2RJ4KJP	12475240			Hallen, S; Bjorquist, A; Ostlund-Lindqvist, AM; Sachs, G	UCLA and the Wadsworth Veterans Administration Hospital	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390996&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			9841699	160870079		CHEMBL2074988				ZINC67886737	1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51065394	CCCC[C@]1(CC)CS(=O)(=O)c2cc(OC)c(OC)cc2[C@H](N1)c1ccccc1	InChI=1S/C23H31NO4S/c1-5-7-13-23(6-2)16-29(25,26)21-15-20(28-4)19(27-3)14-18(21)22(24-23)17-11-9-8-10-12-17/h8-12,14-15,22,24H,5-7,13,16H2,1-4H3/t22-,23-/m1/s1	CKFWDLFFXXVSBJ-DHIUTWEWSA-N	50134411	(7R,9R)-7-Butyl-7-ethyl-2,3-dimethoxy-9-phenyl-6,7,8,9-tetrahydro-5-thia-8-aza-benzocycloheptene 5,5-dioxide::CHEMBL332370	Ileal sodium/bile acid cotransporter	Mus musculus		 3.0							ChEMBL	10.1021/jm400459m	10.7270/Q2MC91D6	23678871			Wu, Y; Aquino, CJ; Cowan, DJ; Anderson, DL; Ambroso, JL; Bishop, MJ; Boros, EE; Chen, L; Cunningham, A; Dobbins, RL; Feldman, PL; Harston, LT; Kaldor, IW; Klein, R; Liang, X; McIntyre, MS; Merrill, CL; Patterson, KM; Prescott, JS; Ray, JS; Roller, SG; Yao, X; Young, A; Yuen, J; Collins, JL	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50134411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50134411&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			9823277	104025005		CHEMBL332370		6529		ZINC53040038	1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51065399	CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNCCS(O)(=O)=O)c(OC)cc2[C@H](N1)c1ccccc1	InChI=1S/C25H36N2O6S2/c1-4-6-12-25(5-2)18-34(28,29)23-15-20(17-26-13-14-35(30,31)32)22(33-3)16-21(23)24(27-25)19-10-8-7-9-11-19/h7-11,15-16,24,26-27H,4-6,12-14,17-18H2,1-3H3,(H,30,31,32)/t24-,25-/m1/s1	CYDNTKYPQAZFFS-JWQCQUIFSA-N	50434846	CHEMBL2387399::US9040518, 35	Ileal sodium/bile acid cotransporter	Mus musculus		 0.900000							ChEMBL	10.1021/jm400459m	10.7270/Q2MC91D6	23678871			Wu, Y; Aquino, CJ; Cowan, DJ; Anderson, DL; Ambroso, JL; Bishop, MJ; Boros, EE; Chen, L; Cunningham, A; Dobbins, RL; Feldman, PL; Harston, LT; Kaldor, IW; Klein, R; Liang, X; McIntyre, MS; Merrill, CL; Patterson, KM; Prescott, JS; Ray, JS; Roller, SG; Yao, X; Young, A; Yuen, J; Collins, JL	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434846&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			71733736	175447163		CHEMBL2387399			C15521	ZINC96270853	1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51065400	CCCC[C@]1(CC)CS(=O)(=O)c2cc(CP(O)(O)=O)c(OC)cc2[C@H](N1)c1ccccc1	InChI=1S/C23H32NO6PS/c1-4-6-12-23(5-2)16-32(28,29)21-13-18(15-31(25,26)27)20(30-3)14-19(21)22(24-23)17-10-8-7-9-11-17/h7-11,13-14,22,24H,4-6,12,15-16H2,1-3H3,(H2,25,26,27)/t22-,23-/m1/s1	KSROWRDKNMGWAM-DHIUTWEWSA-N	50434849	CHEMBL2385105::US9040518, 6	Ileal sodium/bile acid cotransporter	Mus musculus		 0.500000							ChEMBL	10.1021/jm400459m	10.7270/Q2MC91D6	23678871			Wu, Y; Aquino, CJ; Cowan, DJ; Anderson, DL; Ambroso, JL; Bishop, MJ; Boros, EE; Chen, L; Cunningham, A; Dobbins, RL; Feldman, PL; Harston, LT; Kaldor, IW; Klein, R; Liang, X; McIntyre, MS; Merrill, CL; Patterson, KM; Prescott, JS; Ray, JS; Roller, SG; Yao, X; Young, A; Yuen, J; Collins, JL	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434849&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			71237567	175447166		CHEMBL2385105				ZINC96270854	1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51065401	CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNC)c(OC)cc2[C@H](N1)c1ccccc1	InChI=1S/C24H34N2O3S/c1-5-7-13-24(6-2)17-30(27,28)22-14-19(16-25-3)21(29-4)15-20(22)23(26-24)18-11-9-8-10-12-18/h8-12,14-15,23,25-26H,5-7,13,16-17H2,1-4H3/t23-,24-/m1/s1	PSEOJRNRVYUGFW-DNQXCXABSA-N	159808	BDBM50434850::US9040518, 25	Ileal sodium/bile acid cotransporter	Mus musculus		 0.300000							ChEMBL	10.1021/jm400459m	10.7270/Q2MC91D6	23678871			Wu, Y; Aquino, CJ; Cowan, DJ; Anderson, DL; Ambroso, JL; Bishop, MJ; Boros, EE; Chen, L; Cunningham, A; Dobbins, RL; Feldman, PL; Harston, LT; Kaldor, IW; Klein, R; Liang, X; McIntyre, MS; Merrill, CL; Patterson, KM; Prescott, JS; Ray, JS; Roller, SG; Yao, X; Young, A; Yuen, J; Collins, JL	Glaxosmithkline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=159808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=159808&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			71241832	277285761							1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51065427	CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNC(CC(O)=O)CC(O)=O)c(OC)cc2[C@H](N1)c1ccccc1	InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15-26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1	CZGVOBIGEBDYTP-VSGBNLITSA-N	47370	BDBM50434858::US9040518, 26	Ileal sodium/bile acid cotransporter	Mus musculus		 2.1							ChEMBL	10.1021/jm400459m	10.7270/Q2MC91D6	23678871			Wu, Y; Aquino, CJ; Cowan, DJ; Anderson, DL; Ambroso, JL; Bishop, MJ; Boros, EE; Chen, L; Cunningham, A; Dobbins, RL; Feldman, PL; Harston, LT; Kaldor, IW; Klein, R; Liang, X; McIntyre, MS; Merrill, CL; Patterson, KM; Prescott, JS; Ray, JS; Roller, SG; Yao, X; Young, A; Yuen, J; Collins, JL	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47370&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			3427652	24836954							1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51119675	OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC(=O)c1ccc(COc2cc(Cl)c(CN3CSC[C@H]3C(=O)N3CCN(C4CC4)c4ccccc34)cc2Cl)cc1	InChI=1S/C36H42Cl2N4O8S/c37-25-14-32(50-18-21-5-7-22(8-6-21)35(48)39-15-30(44)33(46)34(47)31(45)17-43)26(38)13-23(25)16-40-20-51-19-29(40)36(49)42-12-11-41(24-9-10-24)27-3-1-2-4-28(27)42/h1-8,13-14,24,29-31,33-34,43-47H,9-12,15-20H2,(H,39,48)/t29-,30-,31+,33+,34+/m0/s1	VQICVPORQPLTMV-IKVATAHOSA-N	50459099	CHEMBL4202981	Ileal sodium/bile acid cotransporter	Mus musculus		<25119							ChEMBL	10.1021/acs.jmedchem.8b00308	10.7270/Q2B56NCH	30141927			Chen, T; Reich, NW; Bell, N; Finn, PD; Rodriguez, D; Kohler, J; Kozuka, K; He, L; Spencer, AG; Charmot, D; Navre, M; Carreras, CW; Koo-McCoy, S; Tabora, J; Caldwell, JS; Jacobs, JW; Lewis, JG	Ardelyx, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50459099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50459099&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			71599441	433926364							1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51119748	Clc1ccc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)c1	InChI=1S/C22H23Cl2N3OS/c23-16-5-8-18(24)15(11-16)12-25-14-29-13-21(25)22(28)27-10-9-26(17-6-7-17)19-3-1-2-4-20(19)27/h1-5,8,11,17,21H,6-7,9-10,12-14H2/t21-/m0/s1	QFJZLEQGGSAPMB-NRFANRHFSA-N	50459098	CHEMBL4205214	Ileal sodium/bile acid cotransporter	Mus musculus		<25119							ChEMBL	10.1021/acs.jmedchem.8b00308	10.7270/Q2B56NCH	30141927			Chen, T; Reich, NW; Bell, N; Finn, PD; Rodriguez, D; Kohler, J; Kozuka, K; He, L; Spencer, AG; Charmot, D; Navre, M; Carreras, CW; Koo-McCoy, S; Tabora, J; Caldwell, JS; Jacobs, JW; Lewis, JG	Ardelyx, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50459098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50459098&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			71660821	433926363							1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7						
51119749	OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC(=O)NCCCCc1cc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)cc1Cl	InChI=1S/C33H45Cl2N5O7S/c34-23-14-21(24(35)13-20(23)5-3-4-10-36-33(47)37-15-28(42)30(44)31(45)29(43)17-41)16-38-19-48-18-27(38)32(46)40-12-11-39(22-8-9-22)25-6-1-2-7-26(25)40/h1-2,6-7,13-14,22,27-31,41-45H,3-5,8-12,15-19H2,(H2,36,37,47)/t27-,28-,29+,30+,31+/m0/s1	ROSGDMMWEXIKFJ-OXMBMXHISA-N	50459096	CHEMBL4217797	Ileal sodium/bile acid cotransporter	Mus musculus		<25119							ChEMBL	10.1021/acs.jmedchem.8b00308	10.7270/Q2B56NCH	30141927			Chen, T; Reich, NW; Bell, N; Finn, PD; Rodriguez, D; Kohler, J; Kozuka, K; He, L; Spencer, AG; Charmot, D; Navre, M; Carreras, CW; Koo-McCoy, S; Tabora, J; Caldwell, JS; Jacobs, JW; Lewis, JG	Ardelyx, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50459096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50006114&target=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50459096&enzyme=Ileal+sodium%2Fbile+acid+cotransporter&column=ki&startPg=0&Increment=50&submit=Search			145974037	433926361							1	MDNSSVCPPNATVCEGDSCVVPESNFNAILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK		Ileal sodium/bile acid cotransporter	NTCP2_MOUSE	P70172	Q8VI83 Q925U7