BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50904343 Cc1ccc(Nc2nnc(CSc3ccc(Cl)cc3)s2)c(c1)S(O)(=O)=O InChI=1S/C16H14ClN3O3S3/c1-10-2-7-13(14(8-10)26(21,22)23)18-16-20-19-15(25-16)9-24-12-5-3-11(17)4-6-12/h2-8H,9H2,1H3,(H,18,20)(H,21,22,23) LFAIDABUOLWUEQ-UHFFFAOYSA-N 50300687 2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol-2-ylamino)-5-methylbenzenesulfonic acid::CHEMBL573503 Penicillin-binding protein 2X >1000000 ChEMBL 10.1021/jm900625q 10.7270/Q2NV9K68 19746934 Miguet, L; Zervosen, A; Gerards, T; Pasha, FA; Luxen, A; Disteche-Nguyen, M; Thomas, A Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300687&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 340092 104155048 CHEMBL573503 ZINC01587180 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50904345 OS(=O)(=O)c1c(Cl)ccc(Oc2ccc(Cl)c(Cl)c2)c1NC(=O)Nc1cccc(c1)C(F)(F)F InChI=1S/C20H12Cl3F3N2O5S/c21-13-5-4-12(9-15(13)23)33-16-7-6-14(22)18(34(30,31)32)17(16)28-19(29)27-11-3-1-2-10(8-11)20(24,25)26/h1-9H,(H2,27,28,29)(H,30,31,32) QRHIXNFPZKMURE-UHFFFAOYSA-N 50300688 6-chloro-3-(3,4-dichlorophenoxy)-2-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonic acid::CHEMBL576555 Penicillin-binding protein 2X 255000 ChEMBL 10.1021/jm900625q 10.7270/Q2NV9K68 19746934 Miguet, L; Zervosen, A; Gerards, T; Pasha, FA; Luxen, A; Disteche-Nguyen, M; Thomas, A Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300688&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 423228 104155049 CHEMBL576555 ZINC01555850 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50904346 Cc1cc(Cl)ccc1NC(=O)Nc1c(Oc2ccc(Cl)cc2)ccc(Cl)c1S(O)(=O)=O InChI=1S/C20H15Cl3N2O5S/c1-11-10-13(22)4-8-16(11)24-20(26)25-18-17(30-14-5-2-12(21)3-6-14)9-7-15(23)19(18)31(27,28)29/h2-10H,1H3,(H2,24,25,26)(H,27,28,29) DRXBXQAFEIOKPV-UHFFFAOYSA-N 50300689 6-chloro-2-(3-(4-chloro-2-methylphenyl)ureido)-3-(4-chlorophenoxy)benzenesulfonic acid::CHEMBL575313 Penicillin-binding protein 2X 336000 ChEMBL 10.1021/jm900625q 10.7270/Q2NV9K68 19746934 Miguet, L; Zervosen, A; Gerards, T; Pasha, FA; Luxen, A; Disteche-Nguyen, M; Thomas, A Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300689&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 423151 104155050 CHEMBL575313 ZINC01761821 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939617 OB(O)CNC(=O)c1c(F)cccc1F InChI=1S/C8H8BF2NO3/c10-5-2-1-3-6(11)7(5)8(13)12-4-9(14)15/h1-3,14-15H,4H2,(H,12,13) AKEYJDGPXBVHGK-UHFFFAOYSA-N 50385262 CHEMBL2035285 Penicillin-binding protein 2X 906000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385262&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 70696416 160864345 CHEMBL2035285 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939618 OB(O)CNC(=O)c1ccccc1Cl InChI=1S/C8H9BClNO3/c10-7-4-2-1-3-6(7)8(12)11-5-9(13)14/h1-4,13-14H,5H2,(H,11,12) LXIUYRUEMMFAQV-UHFFFAOYSA-N 50385263 CHEMBL2035289 Penicillin-binding protein 2X 262000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385263&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search BH6 2Y4A 70683815 160864346 CHEMBL2035289 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939619 OB(O)CNC(=O)Cc1ccccc1Cl InChI=1S/C9H11BClNO3/c11-8-4-2-1-3-7(8)5-9(13)12-6-10(14)15/h1-4,14-15H,5-6H2,(H,12,13) IZWAMWPBCQLLFU-UHFFFAOYSA-N 50385264 CHEMBL2035290 Penicillin-binding protein 2X 649000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385264&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 70688081 160864347 CHEMBL2035290 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939620 OB(O)CNC(=O)Cc1ccccc1[N+]([O-])=O InChI=1S/C9H11BN2O5/c13-9(11-6-10(14)15)5-7-3-1-2-4-8(7)12(16)17/h1-4,14-15H,5-6H2,(H,11,13) RBAGLZAUGSLGKC-UHFFFAOYSA-N 50385265 CHEMBL2035293 Penicillin-binding protein 2X 339000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385265&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 70688082 160864348 CHEMBL2035293 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939621 OB(O)CNC(=O)c1ccccc1C(F)(F)F InChI=1S/C9H9BF3NO3/c11-9(12,13)7-4-2-1-3-6(7)8(15)14-5-10(16)17/h1-4,16-17H,5H2,(H,14,15) VXPCKGWBOQCGNA-UHFFFAOYSA-N 50385266 CHEMBL2035295 Penicillin-binding protein 2X 481000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385266&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 70690106 160864349 CHEMBL2035295 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939628 OB(O)CNC(=O)Cc1ccc(Cl)cc1 InChI=1S/C9H11BClNO3/c11-8-3-1-7(2-4-8)5-9(13)12-6-10(14)15/h1-4,14-15H,5-6H2,(H,12,13) NKQSISLJUWJPIO-UHFFFAOYSA-N 50385269 CHEMBL2035301 Penicillin-binding protein 2X 376000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385269&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 70685945 160864352 CHEMBL2035301 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939633 COc1cccc(OC)c1C(=O)NCB(O)O InChI=1S/C10H14BNO5/c1-16-7-4-3-5-8(17-2)9(7)10(13)12-6-11(14)15/h3-5,14-15H,6H2,1-2H3,(H,12,13) SXURQNHWSSEFLG-UHFFFAOYSA-N 50385267 CHEMBL2035284 Penicillin-binding protein 2X 278000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385267&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search B07 3ZVT 54330214 160864350 CHEMBL2035284 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676 50939634 OB(O)CNC(=O)c1ccccc1[N+]([O-])=O InChI=1S/C8H9BN2O5/c12-8(10-5-9(13)14)6-3-1-2-4-7(6)11(15)16/h1-4,13-14H,5H2,(H,10,12) JVDXOQKTWCZCLC-UHFFFAOYSA-N 50385268 CHEMBL2035292 Penicillin-binding protein 2X 138000 ChEMBL 10.1016/j.bmc.2012.04.018 10.7270/Q200034N 22579615 Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Universit£ de Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50385268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005941&target=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50385268&enzyme=Penicillin-binding+protein+2X&column=ki&startPg=0&Increment=50&submit=Search 66561495 160864351 CHEMBL2035292 1 MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 1PMD,1QME,1QMF,2Z2L,2Z2M,2ZC3,2ZC4,5OAU,5OIZ,5OJ0,5OJ1 Penicillin-binding protein 2X PBPX_STRR6 P59676