BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50868330 Nc1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1 InChI=1S/C19H17ClN2O2/c20-18-10-16(21)7-6-15(18)12-22-9-8-17(11-19(22)23)24-13-14-4-2-1-3-5-14/h1-11H,12-13,21H2 VDPUOHFJPAWBKO-UHFFFAOYSA-N 50377084 CHEMBL260770 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377084&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 25167901 160856167 CHEMBL260770 ZINC29047644 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868331 [O-][N+](=O)c1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1 InChI=1S/C19H15ClN2O4/c20-18-10-16(22(24)25)7-6-15(18)12-21-9-8-17(11-19(21)23)26-13-14-4-2-1-3-5-14/h1-11H,12-13H2 RIQOGTFTKRBIMQ-UHFFFAOYSA-N 50326325 1-(2-chloro-4-nitrobenzyl)-4-(benzyloxy)pyridin-2(1H)-one::4-(benzyloxy)-1-(2-chloro-4-nitrobenzyl)pyridin-2(1H)-one::CHEMBL260771 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 3700 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326325&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449562 123105440 CHEMBL260771 ZINC29047650 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868332 OC(=O)c1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1 InChI=1S/C20H16ClNO4/c21-18-10-15(20(24)25)6-7-16(18)12-22-9-8-17(11-19(22)23)26-13-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,24,25) KWEJXOWFJZXSQP-UHFFFAOYSA-N 50377085 CHEMBL260915 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 23800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377085&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449593 160856168 CHEMBL260915 ZINC29047773 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868333 NC(=O)c1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1 InChI=1S/C20H17ClN2O3/c21-18-10-15(20(22)25)6-7-16(18)12-23-9-8-17(11-19(23)24)26-13-14-4-2-1-3-5-14/h1-11H,12-13H2,(H2,22,25) MHMAAFIIFGJJGY-UHFFFAOYSA-N 50377086 CHEMBL261109 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 3600 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377086&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449595 160856169 CHEMBL261109 ZINC29047780 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868334 Clc1cc(ccc1Cn1ccc(OCc2ccccc2)cc1=O)C#N InChI=1S/C20H15ClN2O2/c21-19-10-16(12-22)6-7-17(19)13-23-9-8-18(11-20(23)24)25-14-15-4-2-1-3-5-15/h1-11H,13-14H2 QFGISWQPKALNCO-UHFFFAOYSA-N 50326328 4-((4-(benzyloxy)-2-oxopyridin-1(2H)-yl)methyl)-3-chlorobenzonitrile::CHEMBL407894 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 7000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326328&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449594 123105443 CHEMBL407894 ZINC29047778 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868335 Clc1ccccc1Cn1ccc(OCCCn2ccnc2)cc1=O InChI=1S/C18H18ClN3O2/c19-17-5-2-1-4-15(17)13-22-9-6-16(12-18(22)23)24-11-3-8-21-10-7-20-14-21/h1-2,4-7,9-10,12,14H,3,8,11,13H2 RHMVLKZRKSFURU-UHFFFAOYSA-N 50377087 CHEMBL261637 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 28000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377087&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449630 160856170 CHEMBL261637 ZINC29047912 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868336 Clc1ccccc1Cn1ccc(OCCCn2nnc3ccccc23)cc1=O InChI=1S/C21H19ClN4O2/c22-18-7-2-1-6-16(18)15-25-12-10-17(14-21(25)27)28-13-5-11-26-20-9-4-3-8-19(20)23-24-26/h1-4,6-10,12,14H,5,11,13,15H2 PZYZXQLBYSXCSC-UHFFFAOYSA-N 50377088 CHEMBL261420 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 1600 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377088&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449629 160856171 CHEMBL261420 ZINC29047910 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868337 Clc1ccccc1Cn1ccc(OCCCn2ccc3ccccc23)cc1=O InChI=1S/C23H21ClN2O2/c24-21-8-3-1-7-19(21)17-26-14-11-20(16-23(26)27)28-15-5-12-25-13-10-18-6-2-4-9-22(18)25/h1-4,6-11,13-14,16H,5,12,15,17H2 VHZJTPXVMGCZDY-UHFFFAOYSA-N 50377089 CHEMBL261638 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377089&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449631 160856172 CHEMBL261638 ZINC29047915 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868340 Clc1ccccc1Cn1ccc(OCc2ccc(cc2)C#N)cc1=O InChI=1S/C20H15ClN2O2/c21-19-4-2-1-3-17(19)13-23-10-9-18(11-20(23)24)25-14-16-7-5-15(12-22)6-8-16/h1-11H,13-14H2 HXAFECGSNVCNLM-UHFFFAOYSA-N 50377092 CHEMBL403703 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 2700 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377092&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449701 160856175 CHEMBL403703 ZINC29048142 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868341 Clc1ccccc1Cn1ccc(OCc2ccccc2)cc1=O InChI=1S/C19H16ClNO2/c20-18-9-5-4-8-16(18)13-21-11-10-17(12-19(21)22)23-14-15-6-2-1-3-7-15/h1-12H,13-14H2 NOCOHMWGLHWBFS-UHFFFAOYSA-N 50326326 1-(2-chlorobenzyl)-4-(benzyloxy)pyridin-2(1H)-one::4-(benzyloxy)-1-(2-chlorobenzyl)pyridin-2(1H)-one::CHEMBL260087 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 1500 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326326&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 16046253 123105441 CHEMBL260087 ZINC29048283 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868342 O=c1cc(OCc2ccccc2)ccn1Cc1ccccc1 InChI=1S/C19H17NO2/c21-19-13-18(22-15-17-9-5-2-6-10-17)11-12-20(19)14-16-7-3-1-4-8-16/h1-13H,14-15H2 MPCPIBFZAKSVAX-UHFFFAOYSA-N 50240029 1-benzyl-4-(benzyloxy)pyridin-2(1H)-one::CHEMBL265448 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 6800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240029&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 10193032 104098229 CHEMBL265448 ZINC29048294 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868343 COc1ccc(Oc2ccccc2Cl)c[n+]1[O-] InChI=1S/C12H10ClNO3/c1-16-12-7-6-9(8-14(12)15)17-11-5-3-2-4-10(11)13/h2-8H,1H3 LAJHSKJBVMXCHZ-UHFFFAOYSA-N 50377093 CHEMBL406046 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377093&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449527 160856176 CHEMBL406046 ZINC29047501 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868344 CCOC(=O)c1cc(Cn2ccc(OCc3ccccc3)cc2=O)on1 InChI=1S/C19H18N2O5/c1-2-24-19(23)17-10-16(26-20-17)12-21-9-8-15(11-18(21)22)25-13-14-6-4-3-5-7-14/h3-11H,2,12-13H2,1H3 UNJSZXKNDISPCI-UHFFFAOYSA-N 50377094 CHEMBL407637 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377094&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449529 160856177 CHEMBL407637 ZINC29047512 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868345 O=c1cc(OCc2ccccc2)ccn1CC#C InChI=1S/C15H13NO2/c1-2-9-16-10-8-14(11-15(16)17)18-12-13-6-4-3-5-7-13/h1,3-8,10-11H,9,12H2 RYMMYIKJVZTFPY-UHFFFAOYSA-N 50377095 CHEMBL259486 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377095&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449560 160856178 CHEMBL259486 ZINC29047642 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868346 O=c1cc(OCCCn2c3ccccc3c3ccccc23)ccn1Cc1ccccc1 InChI=1S/C27H24N2O2/c30-27-19-22(15-17-28(27)20-21-9-2-1-3-10-21)31-18-8-16-29-25-13-6-4-11-23(25)24-12-5-7-14-26(24)29/h1-7,9-15,17,19H,8,16,18,20H2 JVMMVAMVYZNGOE-UHFFFAOYSA-N 50377096 CHEMBL260418 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377096&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449659 160856179 CHEMBL260418 ZINC29048007 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868347 COc1ccc(Cn2ccc(OCCCn3c4ccccc4c4ccccc34)cc2=O)cc1 InChI=1S/C28H26N2O3/c1-32-22-13-11-21(12-14-22)20-29-17-15-23(19-28(29)31)33-18-6-16-30-26-9-4-2-7-24(26)25-8-3-5-10-27(25)30/h2-5,7-15,17,19H,6,16,18,20H2,1H3 KQBWZCYCTLKATL-UHFFFAOYSA-N 50377097 CHEMBL260257 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >3000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377097&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449661 160856180 CHEMBL260257 ZINC29048012 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868348 Clc1ccccc1Cn1ccc(OCCCn2c3ccccc3c3ccccc23)cc1=O InChI=1S/C27H23ClN2O2/c28-24-11-4-1-8-20(24)19-29-16-14-21(18-27(29)31)32-17-7-15-30-25-12-5-2-9-22(25)23-10-3-6-13-26(23)30/h1-6,8-14,16,18H,7,15,17,19H2 ZYCNTFPWNABXJA-UHFFFAOYSA-N 50326324 1-(2-chlorobenzyl)-4-(3-(9H-carbazol-9-yl)propoxy)pyridin-2(1H)-one::4-(3-(9H-carbazol-9-yl)propoxy)-1-(2-chlorobenzyl)pyridin-2(1H)-one::CHEMBL408939 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >6000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326324&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449660 123105439 CHEMBL408939 ZINC29048009 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868349 Oc1ccc(Cn2ccc(O)cc2=O)cc1 InChI=1S/C12H11NO3/c14-10-3-1-9(2-4-10)8-13-6-5-11(15)7-12(13)16/h1-7,14-15H,8H2 YKCLTQWPDQIONW-UHFFFAOYSA-N 50377098 CHEMBL262591 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377098&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 54734085 160856181 CHEMBL262591 ZINC29048291 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868350 COc1ccc(Cn2ccc(O)cc2=O)cc1 InChI=1S/C13H13NO3/c1-17-12-4-2-10(3-5-12)9-14-7-6-11(15)8-13(14)16/h2-8,15H,9H2,1H3 ZXXOKWGPGJNNFB-UHFFFAOYSA-N 50377099 CHEMBL255518 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377099&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 54736914 160856182 CHEMBL255518 ZINC29046291 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868351 COc1ccc(Oc2ccc(Cl)cc2Cl)c(=O)[nH]1 InChI=1S/C12H9Cl2NO3/c1-17-11-5-4-10(12(16)15-11)18-9-3-2-7(13)6-8(9)14/h2-6H,1H3,(H,15,16) QETLEWLVGLUGTF-UHFFFAOYSA-N 50377100 CHEMBL260652 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 23700 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377100&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449526 160856183 CHEMBL260652 ZINC29047498 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868352 Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H XEFQLINVKFYRCS-UHFFFAOYSA-N 8726 5-chloro-2-(2,4-dichlorophenoxy)phenol::CHEMBL849::TCL::Triclosan Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 500 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8726&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search TCL 2O2S,4M89,1UH5,4NR0,3PJF,3PJE,3PJD,6AH9,2O2Y,5YCS,1P45,3OID,3OIF,1QSG,2B35,2QIO,3P9T,3NRC,3GR6,2WYW,1NHG,5IFL,3AM3,3AM5,1D8A,1QG6,1D7O,3F4B,4W9N,2PD3,1C14,7FCM,4ALL,4ALI 5564 11109466 164200 CHEMBL849 DB08604 C12059 ZINC00002216 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868353 Oc1ccn(Cc2ccccc2)c(=O)c1 InChI=1S/C12H11NO2/c14-11-6-7-13(12(15)8-11)9-10-4-2-1-3-5-10/h1-8,14H,9H2 BWJTWAQPNGXYEP-UHFFFAOYSA-N 50377101 CHEMBL255941 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis >100000 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377101&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 54724181 160856184 CHEMBL255941 ZINC29046289 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868354 [O-][n+]1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl InChI=1S/C11H6Cl3NO2/c12-7-1-3-10(9(14)5-7)17-11-4-2-8(13)6-15(11)16/h1-6H USZLUQXFHVPKOP-UHFFFAOYSA-N 50377102 CHEMBL259937 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 21400 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377102&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449500 160856185 CHEMBL259937 ZINC29047386 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868355 COc1ccc(Oc2ccccc2Cl)c(=O)[nH]1 InChI=1S/C12H10ClNO3/c1-16-11-7-6-10(12(15)14-11)17-9-5-3-2-4-8(9)13/h2-7H,1H3,(H,14,15) LUNGOIBMOVRHQM-UHFFFAOYSA-N 50377103 CHEMBL259630 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 18800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377103&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449528 160856186 CHEMBL259630 ZINC29047508 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868356 O=c1[nH]c(OCc2ccccc2)ccc1Cc1ccccc1 InChI=1S/C19H17NO2/c21-19-17(13-15-7-3-1-4-8-15)11-12-18(20-19)22-14-16-9-5-2-6-10-16/h1-12H,13-14H2,(H,20,21) CYMWRXHCCITOBH-UHFFFAOYSA-N 50377104 CHEMBL259629 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 700 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377104&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 25167902 160856187 CHEMBL259629 ZINC29047506 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868357 CC(=O)Nc1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1 InChI=1S/C21H19ClN2O3/c1-15(25)23-18-8-7-17(20(22)11-18)13-24-10-9-19(12-21(24)26)27-14-16-5-3-2-4-6-16/h2-12H,13-14H2,1H3,(H,23,25) JYAIMARCLUWEQU-UHFFFAOYSA-N 50377105 CHEMBL259268 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 1800 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377105&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449559 160856188 CHEMBL259268 ZINC29047639 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868338 Clc1ccccc1Cn1ccc(OCc2ccc3ccccc3c2)cc1=O InChI=1S/C23H18ClNO2/c24-22-8-4-3-7-20(22)15-25-12-11-21(14-23(25)26)27-16-17-9-10-18-5-1-2-6-19(18)13-17/h1-14H,15-16H2 GZCQMBPYHYUNPY-UHFFFAOYSA-N 50377090 CHEMBL261348 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 1100 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377090&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449663 160856173 CHEMBL261348 ZINC29048017 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621 50868339 Clc1ccccc1Cn1ccc(OCc2cccc3ccccc23)cc1=O InChI=1S/C23H18ClNO2/c24-22-11-4-2-7-18(22)15-25-13-12-20(14-23(25)26)27-16-19-9-5-8-17-6-1-3-10-21(17)19/h1-14H,15-16H2 IPERXMXDKZGARN-UHFFFAOYSA-N 50377091 CHEMBL260368 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Bacillus subtilis 1500 ChEMBL 10.1016/j.bmcl.2008.05.004 10.7270/Q2668F39 18499454 Tipparaju, SK; Joyasawal, S; Forrester, S; Mulhearn, DC; Pegan, S; Johnson, ME; Mesecar, AD; Kozikowski, AP University of Illinois at Chicago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50005737&target=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377091&enzyme=Enoyl-%5Bacyl-carrier-protein%5D+reductase+%5BNADH%5D+FabI&column=ki&startPg=0&Increment=50&submit=Search 44449699 160856174 CHEMBL260368 ZINC29048138 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR 3OIF,3OIG Enoyl-[acyl-carrier-protein] reductase [NADH] FabI FABI_BACSU P54616 O31621