BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50572172 C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H18N5O14P3/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H6-,12,13,14,19,20,21,22,23,24,25,26)/t4-,6-,7-,10-/m1/s1 DKVRNHPCAOHRSI-KQYNXXCUSA-N 50316302 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate::CHEMBL1094973 Eukaryotic translation initiation factor 4E Mus musculus 10 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316302&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGP 7MEU,6FBZ,3CTR,7FGG,5TFB,4TPW,6XYA,7V1I,5ZJY,6EVK,6WRZ,5ZK9,5ABX,6GKJ,4EMR,3GDH,7JHE,6SCX,3QJI,5BXV,2WMC,6O80,3AM7,7V1H,8AOW,6FC1,1IPC,1L8B,7JIB,6WVN,5T48,5T46 644349 104150663 74655 CHEMBL1094973 C03517 ZINC24540363 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572173 C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/t4-,6-,7-,10-/m1/s1 SBASPRRECYVBRF-KQYNXXCUSA-N 50316303 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate::CHEMBL1094974 Eukaryotic translation initiation factor 4E Mus musculus 45 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316303&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886610 104150664 63730 CHEMBL1094974 C03517 ZINC15521877 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572174 C[n+]1cn([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H16N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,22)/t4-,6-,7-,10-/m1/s1 AOKQNZVJJXPUQA-KQYNXXCUSA-N 50316304 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1097198 Eukaryotic translation initiation factor 4E Mus musculus 7500 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316304&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 14393594 104150665 17825 CHEMBL1097198 C03998 ZINC04096273 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572175 Nc1nc2n(c[n+](Cc3ccccc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H20N5O8P/c18-17-19-14-11(15(25)20-17)21(6-9-4-2-1-3-5-9)8-22(14)16-13(24)12(23)10(30-16)7-29-31(26,27)28/h1-5,8,10,12-13,16,23-24H,6-7H2,(H4-,18,19,20,25,26,27,28)/t10-,12-,13-,16-/m1/s1 WMKJRKYLDWLLPS-XNIJJKJLSA-N 50316305 ((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1094975 Eukaryotic translation initiation factor 4E Mus musculus 1320 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316305&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGQ 2V8X 46886611 104150666 CHEMBL1094975 ZINC16052588 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572176 Nc1nc2n(c[n+](Cc3cccc(F)c3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-3-1-2-8(4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 XBPKXJXULBBIPJ-XNIJJKJLSA-N 50316306 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095619 Eukaryotic translation initiation factor 4E Mus musculus 1590 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316306&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886614 104150667 CHEMBL1095619 ZINC49089074 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572177 Nc1nc2n(c[n+](Cc3ccc(Cl)cc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19ClN5O8P/c18-9-3-1-8(2-4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 FNDXXZIKXUWWSU-XNIJJKJLSA-N 50316307 ((2R,3S,4R,5R)-5-(2-Amino-7-(4-chlorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095620 Eukaryotic translation initiation factor 4E Mus musculus 1990 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316307&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886615 104150668 CHEMBL1095620 ZINC49089075 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572178 Nc1nc2n(c[n+](Cc3cccc(Cl)c3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19ClN5O8P/c18-9-3-1-2-8(4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 LNHYRHWHNOSCLV-XNIJJKJLSA-N 50316308 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-chlorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097199 Eukaryotic translation initiation factor 4E Mus musculus 2200 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316308&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886616 104150669 CHEMBL1097199 ZINC49113179 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572179 Nc1nc2n(c[n+](Cc3ccccc3Cl)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19ClN5O8P/c18-9-4-2-1-3-8(9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 ZUAWTVARTFVXMM-XNIJJKJLSA-N 50316309 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095941 Eukaryotic translation initiation factor 4E Mus musculus 2240 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316309&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886617 104150670 CHEMBL1095941 ZINC49089106 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572180 Nc1nc2n(c[n+](Cc3cc(F)ccc3Cl)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H18ClFN5O8P/c18-9-2-1-8(19)3-7(9)4-23-6-24(14-11(23)15(27)22-17(20)21-14)16-13(26)12(25)10(32-16)5-31-33(28,29)30/h1-3,6,10,12-13,16,25-26H,4-5H2,(H4-,20,21,22,27,28,29,30)/t10-,12-,13-,16-/m1/s1 NOKWLXLUIMVIBK-XNIJJKJLSA-N 50316310 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-chloro-5-fluorobenzyl)-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1098608 Eukaryotic translation initiation factor 4E Mus musculus 3100 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316310&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886625 104150671 CHEMBL1098608 ZINC49089018 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572181 Nc1nc2n(c[n+](Cc3ccccc3F)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-4-2-1-3-8(9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 ALRHWJOEXPIOPB-XNIJJKJLSA-N 50316311 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1098931 Eukaryotic translation initiation factor 4E Mus musculus 4390 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316311&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886626 104150672 CHEMBL1098931 ZINC49088100 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572182 Nc1nc2n(c[n+](Cc3ccc(cc3)C(O)=O)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C18H20N5O10P/c19-18-20-14-11(15(26)21-18)22(5-8-1-3-9(4-2-8)17(27)28)7-23(14)16-13(25)12(24)10(33-16)6-32-34(29,30)31/h1-4,7,10,12-13,16,24-25H,5-6H2,(H5-,19,20,21,26,27,28,29,30,31)/t10-,12-,13-,16-/m1/s1 IIPLIRRYNLPNLW-XNIJJKJLSA-N 50316312 ((2R,3S,4R,5R)-5-(2-Amino-7-(4-carboxybenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095608 Eukaryotic translation initiation factor 4E Mus musculus 4590 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316312&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886627 104150673 CHEMBL1095608 ZINC49112033 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572183 COc1cccc(C[n+]2cn([C@@H]3O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]3O)c3nc(N)[nH]c(=O)c23)c1 InChI=1S/C18H22N5O9P/c1-30-10-4-2-3-9(5-10)6-22-8-23(15-12(22)16(26)21-18(19)20-15)17-14(25)13(24)11(32-17)7-31-33(27,28)29/h2-5,8,11,13-14,17,24-25H,6-7H2,1H3,(H4-,19,20,21,26,27,28,29)/t11-,13-,14-,17-/m1/s1 ZYTARHANIGDPTD-LSCFUAHRSA-N 50316313 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-methoxybenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095609 Eukaryotic translation initiation factor 4E Mus musculus 6600 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316313&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886628 104150674 CHEMBL1095609 ZINC49089029 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572184 Nc1nc2n(c[n+](Cc3cccc(c3)C(F)(F)F)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C18H19F3N5O8P/c19-18(20,21)9-3-1-2-8(4-9)5-25-7-26(14-11(25)15(29)24-17(22)23-14)16-13(28)12(27)10(34-16)6-33-35(30,31)32/h1-4,7,10,12-13,16,27-28H,5-6H2,(H4-,22,23,24,29,30,31,32)/t10-,12-,13-,16-/m1/s1 MYLXMDVAWFAVEE-XNIJJKJLSA-N 50316314 ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-7-(3-(trifluoromethyl)benzyl)-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097637 Eukaryotic translation initiation factor 4E Mus musculus 7560 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316314&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886633 104150675 CHEMBL1097637 ZINC49784742 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572185 Nc1nc2n(c[n+](Cc3ccc(F)cc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-3-1-8(2-4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 VLABRVWLURSKLS-XNIJJKJLSA-N 50316315 ((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097971 Eukaryotic translation initiation factor 4E Mus musculus 8220 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316315&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGV 2V8Y 46886634 104150676 CHEMBL1097971 ZINC16052589 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572186 Nc1nc2n(c[n+](Cc3ccc4ccccc4c3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C21H22N5O8P/c22-21-23-18-15(19(29)24-21)25(8-11-5-6-12-3-1-2-4-13(12)7-11)10-26(18)20-17(28)16(27)14(34-20)9-33-35(30,31)32/h1-7,10,14,16-17,20,27-28H,8-9H2,(H4-,22,23,24,29,30,31,32)/t14-,16-,17-,20-/m1/s1 FQWURQMTZLZBIM-WVSUBDOOSA-N 50316316 ((2R,3S,4R,5R)-5-(2-Amino-7-(naphthalen-2-ylmethyl)-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1094639 Eukaryotic translation initiation factor 4E Mus musculus 9050 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316316&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886635 104150677 CHEMBL1094639 ZINC49069043 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572187 Nc1nc2n(c[n+](Cc3cccc(c3)[N+]([O-])=O)c2c(=O)[nH]1)[C@@H]1O[C@H](CO[P+](O)([O-])[O-])[C@@H](O)[C@H]1O InChI=1S/C17H19N6O10P/c18-17-19-14-11(15(26)20-17)21(5-8-2-1-3-9(4-8)23(27)28)7-22(14)16-13(25)12(24)10(33-16)6-32-34(29,30)31/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,18,19,20,26,29,30,31)/t10-,12-,13-,16-/m1/s1 SUMJIKRGNXINOK-XNIJJKJLSA-N 50316317 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-nitrobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1094640 Eukaryotic translation initiation factor 4E Mus musculus 14400 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316317&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886636 104150678 CHEMBL1094640 ZINC49069045 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572188 Cc1cccc(C[n+]2cn([C@@H]3O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]3O)c3nc(N)[nH]c(=O)c23)c1 InChI=1S/C18H22N5O8P/c1-9-3-2-4-10(5-9)6-22-8-23(15-12(22)16(26)21-18(19)20-15)17-14(25)13(24)11(31-17)7-30-32(27,28)29/h2-5,8,11,13-14,17,24-25H,6-7H2,1H3,(H4-,19,20,21,26,27,28,29)/t11-,13-,14-,17-/m1/s1 ZDYDOHUYLVONDN-LSCFUAHRSA-N 50316318 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-methylbenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097967 Eukaryotic translation initiation factor 4E Mus musculus 15800 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316318&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886651 104150679 CHEMBL1097967 ZINC49112509 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572189 Nc1nc2n(c[n+](Cc3cc(Cl)ccc3Cl)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H18Cl2N5O8P/c18-8-1-2-9(19)7(3-8)4-23-6-24(14-11(23)15(27)22-17(20)21-14)16-13(26)12(25)10(32-16)5-31-33(28,29)30/h1-3,6,10,12-13,16,25-26H,4-5H2,(H4-,20,21,22,27,28,29,30)/t10-,12-,13-,16-/m1/s1 JAMLPCSHNKIRFT-XNIJJKJLSA-N 50316319 ((2R,3S,4R,5R)-5-(2-Amino-7-(2,5-dichlorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097968 Eukaryotic translation initiation factor 4E Mus musculus 17300 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316319&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886652 104150680 CHEMBL1097968 ZINC49785010 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572190 Cc1ccccc1C[n+]1cn([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C18H22N5O8P/c1-9-4-2-3-5-10(9)6-22-8-23(15-12(22)16(26)21-18(19)20-15)17-14(25)13(24)11(31-17)7-30-32(27,28)29/h2-5,8,11,13-14,17,24-25H,6-7H2,1H3,(H4-,19,20,21,26,27,28,29)/t11-,13-,14-,17-/m1/s1 GJVCYMNRTXNUKB-LSCFUAHRSA-N 50316320 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-methylbenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097969 Eukaryotic translation initiation factor 4E Mus musculus 69100 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316320&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886653 104150681 CHEMBL1097969 ZINC49089124 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572191 Nc1nc2n(c[n+](Cc3ccccc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H20N5O8P/c18-17-19-14-11(15(25)20-17)21(6-9-4-2-1-3-5-9)8-22(14)16-13(24)12(23)10(30-16)7-29-31(26,27)28/h1-5,8,10,12-13,16,23-24H,6-7H2,(H4-,18,19,20,25,26,27,28)/t10-,12-,13-,16-/m1/s1 WMKJRKYLDWLLPS-XNIJJKJLSA-N 50316305 ((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1094975 Eukaryotic translation initiation factor 4E Mus musculus 790 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316305&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGQ 2V8X 46886611 104150666 CHEMBL1094975 ZINC16052588 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572192 Nc1nc2n(c[n+](Cc3cccc(F)c3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-3-1-2-8(4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 XBPKXJXULBBIPJ-XNIJJKJLSA-N 50316306 ((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1095619 Eukaryotic translation initiation factor 4E Mus musculus 2230 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316306&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886614 104150667 CHEMBL1095619 ZINC49089074 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572193 Nc1nc2n(c[n+](Cc3ccccc3F)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-4-2-1-3-8(9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 ALRHWJOEXPIOPB-XNIJJKJLSA-N 50316311 ((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1098931 Eukaryotic translation initiation factor 4E Mus musculus 3360 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316311&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886626 104150672 CHEMBL1098931 ZINC49088100 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 50572194 Nc1nc2n(c[n+](Cc3ccc(F)cc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H19FN5O8P/c18-9-3-1-8(2-4-9)5-22-7-23(14-11(22)15(26)21-17(19)20-14)16-13(25)12(24)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,24-25H,5-6H2,(H4-,19,20,21,26,27,28,29)/t10-,12-,13-,16-/m1/s1 VLABRVWLURSKLS-XNIJJKJLSA-N 50316315 ((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo-1Hpurin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylphosphate::CHEMBL1097971 Eukaryotic translation initiation factor 4E Mus musculus 7510 ChEMBL 10.1016/j.ejmech.2009.11.054 10.7270/Q21C1X1Q 20060622 Jia, Y; Chiu, TL; Amin, EA; Polunovsky, V; Bitterman, PB; Wagner, CR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316315&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGV 2V8Y 46886634 104150676 CHEMBL1097971 ZINC16052589 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51109002 C[n+]1cn([C@@H]2O[C@H](Cn3cc(nn3)P(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C13H17N8O7P/c1-19-4-21(10-7(19)11(24)16-13(14)15-10)12-9(23)8(22)5(28-12)2-20-3-6(17-18-20)29(25,26)27/h3-5,8-9,12,22-23H,2H2,1H3,(H4-,14,15,16,24,25,26,27)/t5-,8-,9-,12-/m1/s1 OXYNPFVALCVOEE-JJNLEZRASA-N 50452630 CHEMBL4203412 Eukaryotic translation initiation factor 4E Mus musculus 5900 ChEMBL 10.1016/j.bmc.2017.11.032 10.7270/Q2DZ0BWS 29195795 Kozarski, M; Kubacka, D; Wojtczak, BA; Kasprzyk, R; Baranowski, MR; Kowalska, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452630&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 145975543 433921461 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51109003 C[n+]1cn([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H16N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,22)/t4-,6-,7-,10-/m1/s1 AOKQNZVJJXPUQA-KQYNXXCUSA-N 50316304 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1097198 Eukaryotic translation initiation factor 4E Mus musculus 2000 ChEMBL 10.1016/j.bmc.2017.11.032 10.7270/Q2DZ0BWS 29195795 Kozarski, M; Kubacka, D; Wojtczak, BA; Kasprzyk, R; Baranowski, MR; Kowalska, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316304&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 14393594 104150665 17825 CHEMBL1097198 C03998 ZINC04096273 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343389 Nc1nc2n(c[n+](Cc3ccccc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C17H20N5O8P/c18-17-19-14-11(15(25)20-17)21(6-9-4-2-1-3-5-9)8-22(14)16-13(24)12(23)10(30-16)7-29-31(26,27)28/h1-5,8,10,12-13,16,23-24H,6-7H2,(H4-,18,19,20,25,26,27,28)/t10-,12-,13-,16-/m1/s1 WMKJRKYLDWLLPS-XNIJJKJLSA-N 50316305 ((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1094975 Eukaryotic translation initiation factor 4E Mus musculus 460 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316305&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search MGQ 2V8X 46886611 104150666 CHEMBL1094975 ZINC16052588 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343390 C[n+]1cn([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H16N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,22)/t4-,6-,7-,10-/m1/s1 AOKQNZVJJXPUQA-KQYNXXCUSA-N 50316304 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate::CHEMBL1097198 Eukaryotic translation initiation factor 4E Mus musculus 1240 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316304&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 14393594 104150665 17825 CHEMBL1097198 C03998 ZINC04096273 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343391 C[n+]1cn([C@@H]2O[C@H](COP(O)(S)=O)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 InChI=1S/C11H16N5O7PS/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(23-10)2-22-24(20,21)25/h3-4,6-7,10,17-18H,2H2,1H3,(H4-,12,13,14,19,20,21,25)/t4-,6-,7-,10-/m1/s1 IRIAOLOKILXSNT-KQYNXXCUSA-N 50543773 CHEMBL4636472 Eukaryotic translation initiation factor 4E Mus musculus 302 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543773&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156011429 442145336 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343392 Nc1nc([O-])c2[n+](Cc3ccccc3)cn([C@@H]3O[C@H](COP(O)(S)=O)[C@@H](O)[C@H]3O)c2n1 InChI=1S/C17H20N5O7PS/c18-17-19-14-11(15(25)20-17)21(6-9-4-2-1-3-5-9)8-22(14)16-13(24)12(23)10(29-16)7-28-30(26,27)31/h1-5,8,10,12-13,16,23-24H,6-7H2,(H4-,18,19,20,25,26,27,31)/t10-,12-,13-,16-/m1/s1 RHVBFUUBRLMWIC-XNIJJKJLSA-N 50543774 CHEMBL4640855 Eukaryotic translation initiation factor 4E Mus musculus 344 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543774&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156014958 442145337 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343393 C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 InChI=1S/C11H17N5O10P2S/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(25-10)2-24-28(23,29)26-27(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,29)/t4-,6-,7-,10-,28?/m1/s1 JUPJHVDBZIVSFN-ALTRSKMRSA-N 50543775 CHEMBL4640985 Eukaryotic translation initiation factor 4E Mus musculus 18 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543775&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156015871 442145338 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343394 C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 InChI=1S/C11H17N5O10P2S/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(25-10)2-24-28(23,29)26-27(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,29)/t4-,6-,7-,10-,28?/m1/s1 JUPJHVDBZIVSFN-ALTRSKMRSA-N 50543775 CHEMBL4640985 Eukaryotic translation initiation factor 4E Mus musculus 17.7 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543775&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156015871 442145338 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343395 C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/t4-,6-,7-,10-/m1/s1 SBASPRRECYVBRF-KQYNXXCUSA-N 50316303 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate::CHEMBL1094974 Eukaryotic translation initiation factor 4E Mus musculus 49 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316303&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886610 104150664 63730 CHEMBL1094974 C03517 ZINC15521877 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343396 N.C[n+]1cn([C@@H]2O[C@H](COP(O)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543776 CHEMBL4647306 Eukaryotic translation initiation factor 4E Mus musculus >10000 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543776&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156020153 442145339 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343397 N.C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543777 CHEMBL4632744 Eukaryotic translation initiation factor 4E Mus musculus >10000 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543777&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156009469 442145340 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343398 N.C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543777 CHEMBL4632744 Eukaryotic translation initiation factor 4E Mus musculus >10000 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543777&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156009469 442145340 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343399 N.N.C[n+]1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543778 CHEMBL4640425 Eukaryotic translation initiation factor 4E Mus musculus 570 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543778&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156015684 442145341 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343400 N.N.C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)OP(O)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543779 CHEMBL4635767 Eukaryotic translation initiation factor 4E Mus musculus 230 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543779&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156022254 442145342 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343401 N.N.C[n+]1cn([C@@H]2O[C@H](COP(S)(=O)OP(O)(=O)NCCc3c[nH]c4ccccc34)[C@@H](O)[C@H]2O)c2nc(N)nc([O-])c12 50543779 CHEMBL4635767 Eukaryotic translation initiation factor 4E Mus musculus 230 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543779&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156022254 442145342 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343402 N.Nc1nc([O-])c2[n+](Cc3ccccc3)cn([C@@H]3O[C@H](COP(O)(=O)NCCc4c[nH]c5ccccc45)[C@@H](O)[C@H]3O)c2n1 50543780 CHEMBL4646578 Eukaryotic translation initiation factor 4E Mus musculus >10000 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543780&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 156019744 442145343 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415 51343403 C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12 InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/t4-,6-,7-,10-/m1/s1 SBASPRRECYVBRF-KQYNXXCUSA-N 50316303 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate::CHEMBL1094974 Eukaryotic translation initiation factor 4E Mus musculus 70 ChEMBL 10.1016/j.bmc.2020.115523 10.7270/Q2BZ69MF 32362385 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004485&target=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316303&enzyme=Eukaryotic+translation+initiation+factor+4E&column=ki&startPg=0&Increment=50&submit=Search 46886610 104150664 63730 CHEMBL1094974 C03517 ZINC15521877 1 MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 1EJ1,1EJ4,1EJH,1L8B,2W97,4UED,5BXV,5GW6,5J5O,5J5Y,5M7V,5M7W,5M7X,5M7Z,5M80,5M81,5M83,5M84,5OSX,6GKJ,6GKK,6GKL,6U06,6U09,6YLR,6YLT,6YLV Eukaryotic translation initiation factor 4E IF4E_MOUSE P63073 P20415