BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50433824 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)C(C)O)C(O)=O InChI=1S/C25H36Cl2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 QVZKLLUMEYWUMT-WHJBMRRRSA-N 50252753 CHEMBL495100::N-(3,4-Dichlorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 6700 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252753&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568811 104105491 CHEMBL495100 ZINC49881681 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433825 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCc1ccccc1)C(C)O)C(O)=O InChI=1S/C24H36N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h5-9,13-15,17,19-20,25,29H,10-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 DETDSGXQMKQDNJ-VFWSWVEUSA-N 50252714 CHEMBL492643::N-Benzyl-ETAV Disks large homolog 4 Homo sapiens 7200 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252714&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568794 104105457 CHEMBL492643 ZINC45498625 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433826 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H39N5O9/c1-13(2)20(26(39)40)30-22(35)14(3)28-25(38)21(15(4)32)31-24(37)18(10-11-19(33)34)29-23(36)17(27)12-16-8-6-5-7-9-16/h5-9,13-15,17-18,20-21,32H,10-12,27H2,1-4H3,(H,28,38)(H,29,36)(H,30,35)(H,31,37)(H,33,34)(H,39,40)/t14-,15?,17-,18-,20-,21-/m0/s1 ILLATSRMKXLBOS-HWJJFRRQSA-N 50252713 CHEMBL492642::FETAV Disks large homolog 4 Homo sapiens 6300 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252713&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568793 104105456 CHEMBL492642 ZINC49881541 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433827 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)C(C)O)C(O)=O InChI=1S/C29H40N4O8/c1-16(2)24(29(40)41)32-26(37)17(3)31-28(39)25(18(4)34)33-27(38)22(11-12-23(35)36)30-14-13-19-9-10-20-7-5-6-8-21(20)15-19/h5-10,15-18,22,24-25,30,34H,11-14H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)(H,35,36)(H,40,41)/t17-,18?,22-,24-,25-/m0/s1 BVNXVJDQOOZPCM-FZDDQCGTSA-N 50252828 CHEMBL493689::N-(Naphthalene-2-yl)ethyl-ETAV Disks large homolog 4 Homo sapiens 10000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252828&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568837 104105554 CHEMBL493689 ZINC49881699 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433828 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(F)c(F)c1)C(C)O)C(O)=O InChI=1S/C25H36F2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 VPSVLXPCERTAAH-WHJBMRRRSA-N 50252754 CHEMBL538410::N-(3,4-Difluorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 7800 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252754&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568812 104105492 CHEMBL538410 ZINC42963429 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433829 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)C(C)O)C(O)=O InChI=1S/C17H30N4O8/c1-7(2)12(17(28)29)20-14(25)8(3)19-16(27)13(9(4)22)21-15(26)10(18)5-6-11(23)24/h7-10,12-13,22H,5-6,18H2,1-4H3,(H,19,27)(H,20,25)(H,21,26)(H,23,24)(H,28,29)/t8-,9?,10-,12-,13-/m0/s1 VWOKOWYAFVGHDQ-SXZQQOGPSA-N 50252701 CHEMBL493258::ETAV Disks large homolog 4 Homo sapiens 260000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252701&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568788 104105445 CHEMBL493258 C01960 ZINC40953468 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433830 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H40N4O8/c1-15(2)21(26(37)38)29-23(34)16(3)28-25(36)22(17(4)31)30-24(35)19(12-13-20(32)33)27-14-8-11-18-9-6-5-7-10-18/h5-7,9-10,15-17,19,21-22,27,31H,8,11-14H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t16-,17?,19-,21-,22-/m0/s1 UKIJAHRPMGIIOF-DYKQHQKNSA-N 50252752 CHEMBL495099::N-Phenylpropyl-ETAV Disks large homolog 4 Homo sapiens 44000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252752&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568810 104105490 CHEMBL495099 ZINC49881679 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433831 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C25H38N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h5-9,14-16,18,20-21,26,30H,10-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 DJKUAJMLBSOLFF-GDEPEFMTSA-N 50252715 CHEMBL494895::N-Phenylethyl-ETAV Disks large homolog 4 Homo sapiens 14000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252715&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568795 104105458 CHEMBL494895 ZINC49881423 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433832 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCc1ccccc1)C(C)O)C(O)=O InChI=1S/C24H36N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h5-9,13-15,17,19-20,25,29H,10-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 DETDSGXQMKQDNJ-VFWSWVEUSA-N 50252714 CHEMBL492643::N-Benzyl-ETAV Disks large homolog 4 Homo sapiens 63000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252714&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568794 104105457 CHEMBL492643 ZINC45498625 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433833 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H39N5O9/c1-13(2)20(26(39)40)30-22(35)14(3)28-25(38)21(15(4)32)31-24(37)18(10-11-19(33)34)29-23(36)17(27)12-16-8-6-5-7-9-16/h5-9,13-15,17-18,20-21,32H,10-12,27H2,1-4H3,(H,28,38)(H,29,36)(H,30,35)(H,31,37)(H,33,34)(H,39,40)/t14-,15?,17-,18-,20-,21-/m0/s1 ILLATSRMKXLBOS-HWJJFRRQSA-N 50252713 CHEMBL492642::FETAV Disks large homolog 4 Homo sapiens 35000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252713&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568793 104105456 CHEMBL492642 ZINC49881541 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433834 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 APPLGLBBZPGQBX-GDEPEFMTSA-N 50252827 CHEMBL493688::N-Cyclohexylethyl-ETAV Disks large homolog 4 Homo sapiens 11000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252827&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568836 104105553 CHEMBL493688 ZINC49881697 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433835 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C24H42N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h13-17,19-20,25,29H,5-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 NRBYXUOJAWZKTA-VFWSWVEUSA-N 50252826 CHEMBL494486::N-Cyclohexylmethyl-ETAV Disks large homolog 4 Homo sapiens 21000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252826&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568835 104105552 CHEMBL494486 ZINC40429187 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433836 CCCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C21H38N4O8/c1-6-7-10-22-14(8-9-15(27)28)19(30)25-17(13(5)26)20(31)23-12(4)18(29)24-16(11(2)3)21(32)33/h11-14,16-17,22,26H,6-10H2,1-5H3,(H,23,31)(H,24,29)(H,25,30)(H,27,28)(H,32,33)/t12-,13?,14-,16-,17-/m0/s1 DGLIBFYKWHJASP-UPKCPHKASA-N 50252825 CHEMBL494485::N-Butyl-ETAV Disks large homolog 4 Homo sapiens 35000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252825&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568834 104105551 CHEMBL494485 ZINC40954189 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433837 CCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C20H36N4O8/c1-6-9-21-13(7-8-14(26)27)18(29)24-16(12(5)25)19(30)22-11(4)17(28)23-15(10(2)3)20(31)32/h10-13,15-16,21,25H,6-9H2,1-5H3,(H,22,30)(H,23,28)(H,24,29)(H,26,27)(H,31,32)/t11-,12?,13-,15-,16-/m0/s1 NHQFROHPNIZUKF-VSZKUSEYSA-N 50252824 CHEMBL494287::N-Propyl-ETAV Disks large homolog 4 Homo sapiens 35000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252824&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568833 104105550 CHEMBL494287 ZINC40955586 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433838 CCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C19H34N4O8/c1-6-20-12(7-8-13(25)26)17(28)23-15(11(5)24)18(29)21-10(4)16(27)22-14(9(2)3)19(30)31/h9-12,14-15,20,24H,6-8H2,1-5H3,(H,21,29)(H,22,27)(H,23,28)(H,25,26)(H,30,31)/t10-,11?,12-,14-,15-/m0/s1 MEXXBWHVPQDHNP-FYOXFVTASA-N 50252746 CHEMBL492431::N-Ethyl-ETAV Disks large homolog 4 Homo sapiens 69000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252746&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568808 104105484 CHEMBL492431 ZINC45498695 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433839 CN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O8/c1-8(2)13(18(29)30)21-15(26)9(3)20-17(28)14(10(4)23)22-16(27)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,28)(H,21,26)(H,22,27)(H,24,25)(H,29,30)/t9-,10?,11-,13-,14-/m0/s1 LOKBVOQPMLVOAY-CGTOJEAQSA-N 50252702 CHEMBL521656::N-Methyl-ETAV Disks large homolog 4 Homo sapiens 78000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252702&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568789 104105446 CHEMBL521656 ZINC40428770 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433840 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)C(C)O)C(O)=O InChI=1S/C29H40N4O8/c1-16(2)24(29(40)41)32-26(37)17(3)31-28(39)25(18(4)34)33-27(38)22(11-12-23(35)36)30-14-13-19-9-10-20-7-5-6-8-21(20)15-19/h5-10,15-18,22,24-25,30,34H,11-14H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)(H,35,36)(H,40,41)/t17-,18?,22-,24-,25-/m0/s1 BVNXVJDQOOZPCM-FZDDQCGTSA-N 50252828 CHEMBL493689::N-(Naphthalene-2-yl)ethyl-ETAV Disks large homolog 4 Homo sapiens 1000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252828&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568837 104105554 CHEMBL493689 ZINC49881699 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433841 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(F)c(F)c1)C(C)O)C(O)=O InChI=1S/C25H36F2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 VPSVLXPCERTAAH-WHJBMRRRSA-N 50252754 CHEMBL538410::N-(3,4-Difluorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 980 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252754&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568812 104105492 CHEMBL538410 ZINC42963429 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433842 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)C(C)O)C(O)=O InChI=1S/C25H36Cl2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 QVZKLLUMEYWUMT-WHJBMRRRSA-N 50252753 CHEMBL495100::N-(3,4-Dichlorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 2400 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252753&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568811 104105491 CHEMBL495100 ZINC49881681 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433843 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H40N4O8/c1-15(2)21(26(37)38)29-23(34)16(3)28-25(36)22(17(4)31)30-24(35)19(12-13-20(32)33)27-14-8-11-18-9-6-5-7-10-18/h5-7,9-10,15-17,19,21-22,27,31H,8,11-14H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t16-,17?,19-,21-,22-/m0/s1 UKIJAHRPMGIIOF-DYKQHQKNSA-N 50252752 CHEMBL495099::N-Phenylpropyl-ETAV Disks large homolog 4 Homo sapiens 2100 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252752&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568810 104105490 CHEMBL495099 ZINC49881679 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433844 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C25H38N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h5-9,14-16,18,20-21,26,30H,10-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 DJKUAJMLBSOLFF-GDEPEFMTSA-N 50252715 CHEMBL494895::N-Phenylethyl-ETAV Disks large homolog 4 Homo sapiens 4400 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252715&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568795 104105458 CHEMBL494895 ZINC49881423 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433845 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C17H28N4O10/c1-7(2)13(17(30)31)21-15(28)9(5-12(25)26)19-16(29)10(6-22)20-14(27)8(18)3-4-11(23)24/h7-10,13,22H,3-6,18H2,1-2H3,(H,19,29)(H,20,27)(H,21,28)(H,23,24)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 AJXONGJARXYRDO-YVNDNENWSA-N 50253146 CHEMBL494306::ESDV Disks large homolog 4 Homo sapiens 28000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253146&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 25062886 104105745 CHEMBL494306 C01960 ZINC40972282 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433846 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C17H28N4O10/c1-7(2)13(17(30)31)21-15(28)9(5-12(25)26)19-16(29)10(6-22)20-14(27)8(18)3-4-11(23)24/h7-10,13,22H,3-6,18H2,1-2H3,(H,19,29)(H,20,27)(H,21,28)(H,23,24)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 AJXONGJARXYRDO-YVNDNENWSA-N 50253146 CHEMBL494306::ESDV Disks large homolog 4 Homo sapiens 56000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253146&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 25062886 104105745 CHEMBL494306 C01960 ZINC40972282 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433847 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 APPLGLBBZPGQBX-GDEPEFMTSA-N 50252827 CHEMBL493688::N-Cyclohexylethyl-ETAV Disks large homolog 4 Homo sapiens 940 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252827&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568836 104105553 CHEMBL493688 ZINC49881697 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433848 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C24H42N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h13-17,19-20,25,29H,5-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 NRBYXUOJAWZKTA-VFWSWVEUSA-N 50252826 CHEMBL494486::N-Cyclohexylmethyl-ETAV Disks large homolog 4 Homo sapiens 1000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252826&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568835 104105552 CHEMBL494486 ZINC40429187 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433849 CCCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C21H38N4O8/c1-6-7-10-22-14(8-9-15(27)28)19(30)25-17(13(5)26)20(31)23-12(4)18(29)24-16(11(2)3)21(32)33/h11-14,16-17,22,26H,6-10H2,1-5H3,(H,23,31)(H,24,29)(H,25,30)(H,27,28)(H,32,33)/t12-,13?,14-,16-,17-/m0/s1 DGLIBFYKWHJASP-UPKCPHKASA-N 50252825 CHEMBL494485::N-Butyl-ETAV Disks large homolog 4 Homo sapiens 8400 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252825&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568834 104105551 CHEMBL494485 ZINC40954189 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433850 CCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C20H36N4O8/c1-6-9-21-13(7-8-14(26)27)18(29)24-16(12(5)25)19(30)22-11(4)17(28)23-15(10(2)3)20(31)32/h10-13,15-16,21,25H,6-9H2,1-5H3,(H,22,30)(H,23,28)(H,24,29)(H,26,27)(H,31,32)/t11-,12?,13-,15-,16-/m0/s1 NHQFROHPNIZUKF-VSZKUSEYSA-N 50252824 CHEMBL494287::N-Propyl-ETAV Disks large homolog 4 Homo sapiens 7000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252824&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568833 104105550 CHEMBL494287 ZINC40955586 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433851 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C105H188N42O30/c1-7-55(6)80(98(175)140-69(34-36-77(154)155)92(169)143-72(50-148)95(172)142-71(48-78(156)157)94(171)146-79(54(4)5)99(176)177)147-97(174)74(52-150)145-96(173)73(51-149)144-93(170)70(46-53(2)3)141-90(167)62(22-10-13-39-108)133-85(162)63(24-15-41-124-101(113)114)135-87(164)65(26-17-43-126-103(117)118)136-88(165)66(27-18-44-127-104(119)120)138-91(168)68(33-35-75(110)152)139-89(166)67(28-19-45-128-105(121)122)137-86(163)64(25-16-42-125-102(115)116)134-84(161)61(21-9-12-38-107)132-83(160)60(20-8-11-37-106)131-82(159)59(23-14-40-123-100(111)112)130-76(153)49-129-81(158)58(109)47-56-29-31-57(151)32-30-56/h29-32,53-55,58-74,79-80,148-151H,7-28,33-52,106-109H2,1-6H3,(H2,110,152)(H,129,158)(H,130,153)(H,131,159)(H,132,160)(H,133,162)(H,134,161)(H,135,164)(H,136,165)(H,137,163)(H,138,168)(H,139,166)(H,140,175)(H,141,167)(H,142,172)(H,143,169)(H,144,170)(H,145,173)(H,146,171)(H,147,174)(H,154,155)(H,156,157)(H,176,177)(H4,111,112,123)(H4,113,114,124)(H4,115,116,125)(H4,117,118,126)(H4,119,120,127)(H4,121,122,128)/t55-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,79-,80-/m0/s1 XWQVQFBTSBCKLI-FKXNDIMNSA-N 50253145 CHEMBL502630::YGRKKRRQRRR-KLSSIESDV Disks large homolog 4 Homo sapiens 9800 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253145&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 91935893 104105744 CHEMBL502630 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433852 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C105H188N42O30/c1-7-55(6)80(98(175)140-69(34-36-77(154)155)92(169)143-72(50-148)95(172)142-71(48-78(156)157)94(171)146-79(54(4)5)99(176)177)147-97(174)74(52-150)145-96(173)73(51-149)144-93(170)70(46-53(2)3)141-90(167)62(22-10-13-39-108)133-85(162)63(24-15-41-124-101(113)114)135-87(164)65(26-17-43-126-103(117)118)136-88(165)66(27-18-44-127-104(119)120)138-91(168)68(33-35-75(110)152)139-89(166)67(28-19-45-128-105(121)122)137-86(163)64(25-16-42-125-102(115)116)134-84(161)61(21-9-12-38-107)132-83(160)60(20-8-11-37-106)131-82(159)59(23-14-40-123-100(111)112)130-76(153)49-129-81(158)58(109)47-56-29-31-57(151)32-30-56/h29-32,53-55,58-74,79-80,148-151H,7-28,33-52,106-109H2,1-6H3,(H2,110,152)(H,129,158)(H,130,153)(H,131,159)(H,132,160)(H,133,162)(H,134,161)(H,135,164)(H,136,165)(H,137,163)(H,138,168)(H,139,166)(H,140,175)(H,141,167)(H,142,172)(H,143,169)(H,144,170)(H,145,173)(H,146,171)(H,147,174)(H,154,155)(H,156,157)(H,176,177)(H4,111,112,123)(H4,113,114,124)(H4,115,116,125)(H4,117,118,126)(H4,119,120,127)(H4,121,122,128)/t55-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,79-,80-/m0/s1 XWQVQFBTSBCKLI-FKXNDIMNSA-N 50253145 CHEMBL502630::YGRKKRRQRRR-KLSSIESDV Disks large homolog 4 Homo sapiens 4400 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253145&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 91935893 104105744 CHEMBL502630 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433853 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C105H188N42O30/c1-7-55(6)80(98(175)140-69(34-36-77(154)155)92(169)143-72(50-148)95(172)142-71(48-78(156)157)94(171)146-79(54(4)5)99(176)177)147-97(174)74(52-150)145-96(173)73(51-149)144-93(170)70(46-53(2)3)141-90(167)62(22-10-13-39-108)133-85(162)63(24-15-41-124-101(113)114)135-87(164)65(26-17-43-126-103(117)118)136-88(165)66(27-18-44-127-104(119)120)138-91(168)68(33-35-75(110)152)139-89(166)67(28-19-45-128-105(121)122)137-86(163)64(25-16-42-125-102(115)116)134-84(161)61(21-9-12-38-107)132-83(160)60(20-8-11-37-106)131-82(159)59(23-14-40-123-100(111)112)130-76(153)49-129-81(158)58(109)47-56-29-31-57(151)32-30-56/h29-32,53-55,58-74,79-80,148-151H,7-28,33-52,106-109H2,1-6H3,(H2,110,152)(H,129,158)(H,130,153)(H,131,159)(H,132,160)(H,133,162)(H,134,161)(H,135,164)(H,136,165)(H,137,163)(H,138,168)(H,139,166)(H,140,175)(H,141,167)(H,142,172)(H,143,169)(H,144,170)(H,145,173)(H,146,171)(H,147,174)(H,154,155)(H,156,157)(H,176,177)(H4,111,112,123)(H4,113,114,124)(H4,115,116,125)(H4,117,118,126)(H4,119,120,127)(H4,121,122,128)/t55-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,79-,80-/m0/s1 XWQVQFBTSBCKLI-FKXNDIMNSA-N 50253145 CHEMBL502630::YGRKKRRQRRR-KLSSIESDV Disks large homolog 4 Homo sapiens 14000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253145&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 91935893 104105744 CHEMBL502630 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433854 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C66H108N16O26/c1-7-34(6)53(65(106)74-40(19-21-50(91)92)58(99)78-45(29-84)62(103)76-43(26-51(93)94)61(102)81-52(33(4)5)66(107)108)82-64(105)47(31-86)80-63(104)46(30-85)79-59(100)41(24-32(2)3)75-56(97)38(13-9-11-23-68)72-57(98)39(18-20-49(89)90)73-60(101)42(25-35-14-16-36(87)17-15-35)71-48(88)27-70-55(96)44(28-83)77-54(95)37(69)12-8-10-22-67/h14-17,32-34,37-47,52-53,83-87H,7-13,18-31,67-69H2,1-6H3,(H,70,96)(H,71,88)(H,72,98)(H,73,101)(H,74,106)(H,75,97)(H,76,103)(H,77,95)(H,78,99)(H,79,100)(H,80,104)(H,81,102)(H,82,105)(H,89,90)(H,91,92)(H,93,94)(H,107,108)/t34-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,52-,53-/m0/s1 OYOJPGJCPOXGEB-QBAAMSOUSA-N 50253143 CHEMBL445253::KSG-YEKLSSIESDV Disks large homolog 4 Homo sapiens 4100 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253143&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568937 104105742 CHEMBL445253 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433855 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C66H108N16O26/c1-7-34(6)53(65(106)74-40(19-21-50(91)92)58(99)78-45(29-84)62(103)76-43(26-51(93)94)61(102)81-52(33(4)5)66(107)108)82-64(105)47(31-86)80-63(104)46(30-85)79-59(100)41(24-32(2)3)75-56(97)38(13-9-11-23-68)72-57(98)39(18-20-49(89)90)73-60(101)42(25-35-14-16-36(87)17-15-35)71-48(88)27-70-55(96)44(28-83)77-54(95)37(69)12-8-10-22-67/h14-17,32-34,37-47,52-53,83-87H,7-13,18-31,67-69H2,1-6H3,(H,70,96)(H,71,88)(H,72,98)(H,73,101)(H,74,106)(H,75,97)(H,76,103)(H,77,95)(H,78,99)(H,79,100)(H,80,104)(H,81,102)(H,82,105)(H,89,90)(H,91,92)(H,93,94)(H,107,108)/t34-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,52-,53-/m0/s1 OYOJPGJCPOXGEB-QBAAMSOUSA-N 50253143 CHEMBL445253::KSG-YEKLSSIESDV Disks large homolog 4 Homo sapiens 18000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253143&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568937 104105742 CHEMBL445253 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433856 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C66H108N16O26/c1-7-34(6)53(65(106)74-40(19-21-50(91)92)58(99)78-45(29-84)62(103)76-43(26-51(93)94)61(102)81-52(33(4)5)66(107)108)82-64(105)47(31-86)80-63(104)46(30-85)79-59(100)41(24-32(2)3)75-56(97)38(13-9-11-23-68)72-57(98)39(18-20-49(89)90)73-60(101)42(25-35-14-16-36(87)17-15-35)71-48(88)27-70-55(96)44(28-83)77-54(95)37(69)12-8-10-22-67/h14-17,32-34,37-47,52-53,83-87H,7-13,18-31,67-69H2,1-6H3,(H,70,96)(H,71,88)(H,72,98)(H,73,101)(H,74,106)(H,75,97)(H,76,103)(H,77,95)(H,78,99)(H,79,100)(H,80,104)(H,81,102)(H,82,105)(H,89,90)(H,91,92)(H,93,94)(H,107,108)/t34-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,52-,53-/m0/s1 OYOJPGJCPOXGEB-QBAAMSOUSA-N 50253143 CHEMBL445253::KSG-YEKLSSIESDV Disks large homolog 4 Homo sapiens 7000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253143&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568937 104105742 CHEMBL445253 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433857 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C67H113N19O24/c1-32(2)25-42(75-50(94)29-74-56(98)46(30-87)82-55(97)38(71)13-7-10-22-68)60(102)81-45(28-51(95)96)63(105)86-53(34(5)89)65(107)78-40(15-9-12-24-70)58(100)80-44(27-49(73)93)62(104)79-43(26-36-16-18-37(91)19-17-36)61(103)76-39(14-8-11-23-69)57(99)77-41(20-21-48(72)92)59(101)85-54(35(6)90)66(108)83-47(31-88)64(106)84-52(33(3)4)67(109)110/h16-19,32-35,38-47,52-54,87-91H,7-15,20-31,68-71H2,1-6H3,(H2,72,92)(H2,73,93)(H,74,98)(H,75,94)(H,76,103)(H,77,99)(H,78,107)(H,79,104)(H,80,100)(H,81,102)(H,82,97)(H,83,108)(H,84,106)(H,85,101)(H,86,105)(H,95,96)(H,109,110)/t34-,35-,38+,39+,40+,41+,42+,43+,44+,45+,46+,47+,52+,53+,54+/m1/s1 LZIFLRQJFWVNPC-NBGMAUTBSA-N 50253144 CHEMBL505051::KSG-LDTKNYKQTSV Disks large homolog 4 Homo sapiens 97000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253144&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568938 104105743 CHEMBL505051 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433858 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C67H113N19O24/c1-32(2)25-42(75-50(94)29-74-56(98)46(30-87)82-55(97)38(71)13-7-10-22-68)60(102)81-45(28-51(95)96)63(105)86-53(34(5)89)65(107)78-40(15-9-12-24-70)58(100)80-44(27-49(73)93)62(104)79-43(26-36-16-18-37(91)19-17-36)61(103)76-39(14-8-11-23-69)57(99)77-41(20-21-48(72)92)59(101)85-54(35(6)90)66(108)83-47(31-88)64(106)84-52(33(3)4)67(109)110/h16-19,32-35,38-47,52-54,87-91H,7-15,20-31,68-71H2,1-6H3,(H2,72,92)(H2,73,93)(H,74,98)(H,75,94)(H,76,103)(H,77,99)(H,78,107)(H,79,104)(H,80,100)(H,81,102)(H,82,97)(H,83,108)(H,84,106)(H,85,101)(H,86,105)(H,95,96)(H,109,110)/t34-,35-,38+,39+,40+,41+,42+,43+,44+,45+,46+,47+,52+,53+,54+/m1/s1 LZIFLRQJFWVNPC-NBGMAUTBSA-N 50253144 CHEMBL505051::KSG-LDTKNYKQTSV Disks large homolog 4 Homo sapiens 25000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253144&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568938 104105743 CHEMBL505051 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433859 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C67H113N19O24/c1-32(2)25-42(75-50(94)29-74-56(98)46(30-87)82-55(97)38(71)13-7-10-22-68)60(102)81-45(28-51(95)96)63(105)86-53(34(5)89)65(107)78-40(15-9-12-24-70)58(100)80-44(27-49(73)93)62(104)79-43(26-36-16-18-37(91)19-17-36)61(103)76-39(14-8-11-23-69)57(99)77-41(20-21-48(72)92)59(101)85-54(35(6)90)66(108)83-47(31-88)64(106)84-52(33(3)4)67(109)110/h16-19,32-35,38-47,52-54,87-91H,7-15,20-31,68-71H2,1-6H3,(H2,72,92)(H2,73,93)(H,74,98)(H,75,94)(H,76,103)(H,77,99)(H,78,107)(H,79,104)(H,80,100)(H,81,102)(H,82,97)(H,83,108)(H,84,106)(H,85,101)(H,86,105)(H,95,96)(H,109,110)/t34-,35-,38+,39+,40+,41+,42+,43+,44+,45+,46+,47+,52+,53+,54+/m1/s1 LZIFLRQJFWVNPC-NBGMAUTBSA-N 50253144 CHEMBL505051::KSG-LDTKNYKQTSV Disks large homolog 4 Homo sapiens 2100 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253144&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568938 104105743 CHEMBL505051 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433860 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C67H113N19O24/c1-32(2)25-42(75-50(94)29-74-56(98)46(30-87)82-55(97)38(71)13-7-10-22-68)60(102)81-45(28-51(95)96)63(105)86-53(34(5)89)65(107)78-40(15-9-12-24-70)58(100)80-44(27-49(73)93)62(104)79-43(26-36-16-18-37(91)19-17-36)61(103)76-39(14-8-11-23-69)57(99)77-41(20-21-48(72)92)59(101)85-54(35(6)90)66(108)83-47(31-88)64(106)84-52(33(3)4)67(109)110/h16-19,32-35,38-47,52-54,87-91H,7-15,20-31,68-71H2,1-6H3,(H2,72,92)(H2,73,93)(H,74,98)(H,75,94)(H,76,103)(H,77,99)(H,78,107)(H,79,104)(H,80,100)(H,81,102)(H,82,97)(H,83,108)(H,84,106)(H,85,101)(H,86,105)(H,95,96)(H,109,110)/t34-,35-,38+,39+,40+,41+,42+,43+,44+,45+,46+,47+,52+,53+,54+/m1/s1 LZIFLRQJFWVNPC-NBGMAUTBSA-N 50253144 CHEMBL505051::KSG-LDTKNYKQTSV Disks large homolog 4 Homo sapiens 45000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253144&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568938 104105743 CHEMBL505051 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433861 CCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C19H34N4O8/c1-6-20-12(7-8-13(25)26)17(28)23-15(11(5)24)18(29)21-10(4)16(27)22-14(9(2)3)19(30)31/h9-12,14-15,20,24H,6-8H2,1-5H3,(H,21,29)(H,22,27)(H,23,28)(H,25,26)(H,30,31)/t10-,11?,12-,14-,15-/m0/s1 MEXXBWHVPQDHNP-FYOXFVTASA-N 50252746 CHEMBL492431::N-Ethyl-ETAV Disks large homolog 4 Homo sapiens 9300 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252746&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568808 104105484 CHEMBL492431 ZINC45498695 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433862 CN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O8/c1-8(2)13(18(29)30)21-15(26)9(3)20-17(28)14(10(4)23)22-16(27)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,28)(H,21,26)(H,22,27)(H,24,25)(H,29,30)/t9-,10?,11-,13-,14-/m0/s1 LOKBVOQPMLVOAY-CGTOJEAQSA-N 50252702 CHEMBL521656::N-Methyl-ETAV Disks large homolog 4 Homo sapiens 11000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252702&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568789 104105446 CHEMBL521656 ZINC40428770 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433863 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)C(C)O)C(O)=O InChI=1S/C17H30N4O8/c1-7(2)12(17(28)29)20-14(25)8(3)19-16(27)13(9(4)22)21-15(26)10(18)5-6-11(23)24/h7-10,12-13,22H,5-6,18H2,1-4H3,(H,19,27)(H,20,25)(H,21,26)(H,23,24)(H,28,29)/t8-,9?,10-,12-,13-/m0/s1 VWOKOWYAFVGHDQ-SXZQQOGPSA-N 50252701 CHEMBL493258::ETAV Disks large homolog 4 Homo sapiens 29000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252701&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568788 104105445 CHEMBL493258 C01960 ZINC40953468 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433864 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(N)=O)C(O)=O InChI=1S/C17H29N5O9/c1-7(2)13(17(30)31)22-15(28)9(5-12(25)26)20-16(29)10(6-23)21-14(27)8(18)3-4-11(19)24/h7-10,13,23H,3-6,18H2,1-2H3,(H2,19,24)(H,20,29)(H,21,27)(H,22,28)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 FJPPEXQVQYMTNX-YVNDNENWSA-N 50252700 (S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-3-hydroxy-propionylamino]-3-carboxy-propionylamino}-3-methyl-butyric acid::CHEMBL493257 Disks large homolog 4 Homo sapiens 130000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252700&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568787 104105444 CHEMBL493257 C01960 ZINC40953464 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433865 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O InChI=1S/C18H30N4O10/c1-7(2)13(18(31)32)21-16(29)10(6-12(26)27)20-17(30)14(8(3)23)22-15(28)9(19)4-5-11(24)25/h7-10,13-14,23H,4-6,19H2,1-3H3,(H,20,30)(H,21,29)(H,22,28)(H,24,25)(H,26,27)(H,31,32)/t8-,9+,10+,13+,14+/m1/s1 WSIMGVDWHZEOAI-PREJHDKISA-N 50252699 (S)-4-amino-5-((2S,3R)-1-((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxobutan-2-ylamino)-5-oxopentanoic acid::CHEMBL522518 Disks large homolog 4 Homo sapiens 22000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252699&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 11619578 104105443 CHEMBL522518 C01960 ZINC40954153 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433866 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C17H29N5O9/c1-7(2)13(17(30)31)22-15(28)9(5-11(19)24)20-16(29)10(6-23)21-14(27)8(18)3-4-12(25)26/h7-10,13,23H,3-6,18H2,1-2H3,(H2,19,24)(H,20,29)(H,21,27)(H,22,28)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 OWCODBVPZFHRRZ-YVNDNENWSA-N 50253297 (S)-4-amino-5-((S)-1-((S)-4-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,4-dioxobutan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL493105 Disks large homolog 4 Homo sapiens 88000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253297&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44569003 104105845 CHEMBL493105 C01960 ZINC40954775 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433867 CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)22-16(29)10(4-6-13(26)27)20-17(30)11(7-23)21-15(28)9(19)3-5-12(24)25/h8-11,14,23H,3-7,19H2,1-2H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 QKIPWEADEMCLIX-RMIALFOJSA-N 50253262 (S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carboxy-butyrylamino)-3-hydroxy-propionylamino]-4-carboxy-butyrylamino}-3-methyl-butyric acid::CHEMBL522656 Disks large homolog 4 Homo sapiens 67000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253262&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 25062887 104105828 CHEMBL522656 C01960 ZINC42891496 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433868 CC(C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H31N5O9/c1-8(2)14(18(31)32)23-16(29)10(4-5-12(20)25)21-17(30)11(7-24)22-15(28)9(19)3-6-13(26)27/h8-11,14,24H,3-7,19H2,1-2H3,(H2,20,25)(H,21,30)(H,22,28)(H,23,29)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 XMNHLAFMWAEDQB-RMIALFOJSA-N 50253261 (S)-4-amino-5-((S)-1-((S)-5-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,5-dioxopentan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL492284 Disks large homolog 4 Homo sapiens 57000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253261&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568998 104105827 CHEMBL492284 C01960 ZINC40949703 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433869 CC(C)(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-18(2,3)13(17(31)32)22-15(29)9(6-12(26)27)20-16(30)10(7-23)21-14(28)8(19)4-5-11(24)25/h8-10,13,23H,4-7,19H2,1-3H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t8-,9-,10-,13+/m0/s1 YFHJRPDPJMYESB-AVWBDOJWSA-N 50253260 (S)-4-amino-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxy-2,2-dimethylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL493722 Disks large homolog 4 Homo sapiens 76000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253260&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568997 104105826 CHEMBL493722 C01960 ZINC40431316 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433870 CC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C16H26N4O10/c1-2-8(16(29)30)18-14(27)9(5-12(24)25)19-15(28)10(6-21)20-13(26)7(17)3-4-11(22)23/h7-10,21H,2-6,17H2,1H3,(H,18,27)(H,19,28)(H,20,26)(H,22,23)(H,24,25)(H,29,30)/t7-,8-,9-,10-/m0/s1 WNEFKHIVDFGNSU-XKNYDFJKSA-N 50253224 (S)-4-amino-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxypropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL522862 Disks large homolog 4 Homo sapiens 230000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253224&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568993 104105810 CHEMBL522862 C01960 ZINC40953249 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433871 CN[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)22-16(29)10(6-13(26)27)20-17(30)11(7-23)21-15(28)9(19-3)4-5-12(24)25/h8-11,14,19,23H,4-7H2,1-3H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 YGZHTJCMFNVSDW-RMIALFOJSA-N 50253223 (S)-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-4-(methylamino)-5-oxopentanoic acid::CHEMBL523665 Disks large homolog 4 Homo sapiens 24000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253223&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568992 104105809 CHEMBL523665 ZINC40423006 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433872 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)21-16(29)11(6-13(26)27)22(3)17(30)10(7-23)20-15(28)9(19)4-5-12(24)25/h8-11,14,23H,4-7,19H2,1-3H3,(H,20,28)(H,21,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 YTNSANDMIXPEOB-RMIALFOJSA-N 50253222 (S)-4-amino-5-((S)-1-(((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-yl)(methyl)amino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL492272 Disks large homolog 4 Homo sapiens 87000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253222&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568990 104105808 CHEMBL492272 ZINC45498658 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433873 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)C(C)O)C(O)=O InChI=1S/C29H40N4O8/c1-16(2)24(29(40)41)32-26(37)17(3)31-28(39)25(18(4)34)33-27(38)22(11-12-23(35)36)30-14-13-19-9-10-20-7-5-6-8-21(20)15-19/h5-10,15-18,22,24-25,30,34H,11-14H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)(H,35,36)(H,40,41)/t17-,18?,22-,24-,25-/m0/s1 BVNXVJDQOOZPCM-FZDDQCGTSA-N 50252828 CHEMBL493689::N-(Naphthalene-2-yl)ethyl-ETAV Disks large homolog 4 Homo sapiens 950 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252828&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568837 104105554 CHEMBL493689 ZINC49881699 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433874 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(F)c(F)c1)C(C)O)C(O)=O InChI=1S/C25H36F2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 VPSVLXPCERTAAH-WHJBMRRRSA-N 50252754 CHEMBL538410::N-(3,4-Difluorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 1000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252754&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568812 104105492 CHEMBL538410 ZINC42963429 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433875 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)C(C)O)C(O)=O InChI=1S/C25H36Cl2N4O8/c1-12(2)20(25(38)39)30-22(35)13(3)29-24(37)21(14(4)32)31-23(36)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,37)(H,30,35)(H,31,36)(H,33,34)(H,38,39)/t13-,14?,18-,20-,21-/m0/s1 QVZKLLUMEYWUMT-WHJBMRRRSA-N 50252753 CHEMBL495100::N-(3,4-Dichlorophenyl)propyl-ETAV Disks large homolog 4 Homo sapiens 1100 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252753&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568811 104105491 CHEMBL495100 ZINC49881681 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433876 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H40N4O8/c1-15(2)21(26(37)38)29-23(34)16(3)28-25(36)22(17(4)31)30-24(35)19(12-13-20(32)33)27-14-8-11-18-9-6-5-7-10-18/h5-7,9-10,15-17,19,21-22,27,31H,8,11-14H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t16-,17?,19-,21-,22-/m0/s1 UKIJAHRPMGIIOF-DYKQHQKNSA-N 50252752 CHEMBL495099::N-Phenylpropyl-ETAV Disks large homolog 4 Homo sapiens 3100 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252752&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568810 104105490 CHEMBL495099 ZINC49881679 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433877 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccccc1)C(C)O)C(O)=O InChI=1S/C25H38N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h5-9,14-16,18,20-21,26,30H,10-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 DJKUAJMLBSOLFF-GDEPEFMTSA-N 50252715 CHEMBL494895::N-Phenylethyl-ETAV Disks large homolog 4 Homo sapiens 1600 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252715&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568795 104105458 CHEMBL494895 ZINC49881423 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433878 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCc1ccccc1)C(C)O)C(O)=O InChI=1S/C24H36N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h5-9,13-15,17,19-20,25,29H,10-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 DETDSGXQMKQDNJ-VFWSWVEUSA-N 50252714 CHEMBL492643::N-Benzyl-ETAV Disks large homolog 4 Homo sapiens 5200 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252714&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568794 104105457 CHEMBL492643 ZINC45498625 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433879 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(C)O)C(O)=O InChI=1S/C26H39N5O9/c1-13(2)20(26(39)40)30-22(35)14(3)28-25(38)21(15(4)32)31-24(37)18(10-11-19(33)34)29-23(36)17(27)12-16-8-6-5-7-9-16/h5-9,13-15,17-18,20-21,32H,10-12,27H2,1-4H3,(H,28,38)(H,29,36)(H,30,35)(H,31,37)(H,33,34)(H,39,40)/t14-,15?,17-,18-,20-,21-/m0/s1 ILLATSRMKXLBOS-HWJJFRRQSA-N 50252713 CHEMBL492642::FETAV Disks large homolog 4 Homo sapiens 2300 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252713&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568793 104105456 CHEMBL492642 ZINC49881541 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433880 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 APPLGLBBZPGQBX-GDEPEFMTSA-N 50252827 CHEMBL493688::N-Cyclohexylethyl-ETAV Disks large homolog 4 Homo sapiens 450 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252827&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568836 104105553 CHEMBL493688 ZINC49881697 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433881 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C24H42N4O8/c1-13(2)19(24(35)36)27-21(32)14(3)26-23(34)20(15(4)29)28-22(33)17(10-11-18(30)31)25-12-16-8-6-5-7-9-16/h13-17,19-20,25,29H,5-12H2,1-4H3,(H,26,34)(H,27,32)(H,28,33)(H,30,31)(H,35,36)/t14-,15?,17-,19-,20-/m0/s1 NRBYXUOJAWZKTA-VFWSWVEUSA-N 50252826 CHEMBL494486::N-Cyclohexylmethyl-ETAV Disks large homolog 4 Homo sapiens 1300 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252826&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568835 104105552 CHEMBL494486 ZINC40429187 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433882 CCCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C21H38N4O8/c1-6-7-10-22-14(8-9-15(27)28)19(30)25-17(13(5)26)20(31)23-12(4)18(29)24-16(11(2)3)21(32)33/h11-14,16-17,22,26H,6-10H2,1-5H3,(H,23,31)(H,24,29)(H,25,30)(H,27,28)(H,32,33)/t12-,13?,14-,16-,17-/m0/s1 DGLIBFYKWHJASP-UPKCPHKASA-N 50252825 CHEMBL494485::N-Butyl-ETAV Disks large homolog 4 Homo sapiens 4000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252825&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568834 104105551 CHEMBL494485 ZINC40954189 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433883 CCCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C20H36N4O8/c1-6-9-21-13(7-8-14(26)27)18(29)24-16(12(5)25)19(30)22-11(4)17(28)23-15(10(2)3)20(31)32/h10-13,15-16,21,25H,6-9H2,1-5H3,(H,22,30)(H,23,28)(H,24,29)(H,26,27)(H,31,32)/t11-,12?,13-,15-,16-/m0/s1 NHQFROHPNIZUKF-VSZKUSEYSA-N 50252824 CHEMBL494287::N-Propyl-ETAV Disks large homolog 4 Homo sapiens 4200 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252824&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568833 104105550 CHEMBL494287 ZINC40955586 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433884 CCN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C19H34N4O8/c1-6-20-12(7-8-13(25)26)17(28)23-15(11(5)24)18(29)21-10(4)16(27)22-14(9(2)3)19(30)31/h9-12,14-15,20,24H,6-8H2,1-5H3,(H,21,29)(H,22,27)(H,23,28)(H,25,26)(H,30,31)/t10-,11?,12-,14-,15-/m0/s1 MEXXBWHVPQDHNP-FYOXFVTASA-N 50252746 CHEMBL492431::N-Ethyl-ETAV Disks large homolog 4 Homo sapiens 9600 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252746&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568808 104105484 CHEMBL492431 ZINC45498695 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433885 CN[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O8/c1-8(2)13(18(29)30)21-15(26)9(3)20-17(28)14(10(4)23)22-16(27)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,28)(H,21,26)(H,22,27)(H,24,25)(H,29,30)/t9-,10?,11-,13-,14-/m0/s1 LOKBVOQPMLVOAY-CGTOJEAQSA-N 50252702 CHEMBL521656::N-Methyl-ETAV Disks large homolog 4 Homo sapiens 8900 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252702&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568789 104105446 CHEMBL521656 ZINC40428770 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433886 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)C(C)O)C(O)=O InChI=1S/C17H30N4O8/c1-7(2)12(17(28)29)20-14(25)8(3)19-16(27)13(9(4)22)21-15(26)10(18)5-6-11(23)24/h7-10,12-13,22H,5-6,18H2,1-4H3,(H,19,27)(H,20,25)(H,21,26)(H,23,24)(H,28,29)/t8-,9?,10-,12-,13-/m0/s1 VWOKOWYAFVGHDQ-SXZQQOGPSA-N 50252701 CHEMBL493258::ETAV Disks large homolog 4 Homo sapiens 22000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252701&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568788 104105445 CHEMBL493258 C01960 ZINC40953468 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433887 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(N)=O)C(O)=O InChI=1S/C17H29N5O9/c1-7(2)13(17(30)31)22-15(28)9(5-12(25)26)20-16(29)10(6-23)21-14(27)8(18)3-4-11(19)24/h7-10,13,23H,3-6,18H2,1-2H3,(H2,19,24)(H,20,29)(H,21,27)(H,22,28)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 FJPPEXQVQYMTNX-YVNDNENWSA-N 50252700 (S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-3-hydroxy-propionylamino]-3-carboxy-propionylamino}-3-methyl-butyric acid::CHEMBL493257 Disks large homolog 4 Homo sapiens 100000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252700&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568787 104105444 CHEMBL493257 C01960 ZINC40953464 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433888 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O InChI=1S/C18H30N4O10/c1-7(2)13(18(31)32)21-16(29)10(6-12(26)27)20-17(30)14(8(3)23)22-15(28)9(19)4-5-11(24)25/h7-10,13-14,23H,4-6,19H2,1-3H3,(H,20,30)(H,21,29)(H,22,28)(H,24,25)(H,26,27)(H,31,32)/t8-,9+,10+,13+,14+/m1/s1 WSIMGVDWHZEOAI-PREJHDKISA-N 50252699 (S)-4-amino-5-((2S,3R)-1-((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxobutan-2-ylamino)-5-oxopentanoic acid::CHEMBL522518 Disks large homolog 4 Homo sapiens 16000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252699&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 11619578 104105443 CHEMBL522518 C01960 ZINC40954153 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433889 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C17H29N5O9/c1-7(2)13(17(30)31)22-15(28)9(5-11(19)24)20-16(29)10(6-23)21-14(27)8(18)3-4-12(25)26/h7-10,13,23H,3-6,18H2,1-2H3,(H2,19,24)(H,20,29)(H,21,27)(H,22,28)(H,25,26)(H,30,31)/t8-,9-,10-,13-/m0/s1 OWCODBVPZFHRRZ-YVNDNENWSA-N 50253297 (S)-4-amino-5-((S)-1-((S)-4-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,4-dioxobutan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL493105 Disks large homolog 4 Homo sapiens 67000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253297&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44569003 104105845 CHEMBL493105 C01960 ZINC40954775 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433890 CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)22-16(29)10(4-6-13(26)27)20-17(30)11(7-23)21-15(28)9(19)3-5-12(24)25/h8-11,14,23H,3-7,19H2,1-2H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 QKIPWEADEMCLIX-RMIALFOJSA-N 50253262 (S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carboxy-butyrylamino)-3-hydroxy-propionylamino]-4-carboxy-butyrylamino}-3-methyl-butyric acid::CHEMBL522656 Disks large homolog 4 Homo sapiens 29000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253262&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 25062887 104105828 CHEMBL522656 C01960 ZINC42891496 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433891 CC(C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H31N5O9/c1-8(2)14(18(31)32)23-16(29)10(4-5-12(20)25)21-17(30)11(7-24)22-15(28)9(19)3-6-13(26)27/h8-11,14,24H,3-7,19H2,1-2H3,(H2,20,25)(H,21,30)(H,22,28)(H,23,29)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 XMNHLAFMWAEDQB-RMIALFOJSA-N 50253261 (S)-4-amino-5-((S)-1-((S)-5-amino-1-((S)-1-carboxy-2-methylpropylamino)-1,5-dioxopentan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL492284 Disks large homolog 4 Homo sapiens 29000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253261&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568998 104105827 CHEMBL492284 C01960 ZINC40949703 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433892 CC(C)(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-18(2,3)13(17(31)32)22-15(29)9(6-12(26)27)20-16(30)10(7-23)21-14(28)8(19)4-5-11(24)25/h8-10,13,23H,4-7,19H2,1-3H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t8-,9-,10-,13+/m0/s1 YFHJRPDPJMYESB-AVWBDOJWSA-N 50253260 (S)-4-amino-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxy-2,2-dimethylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL493722 Disks large homolog 4 Homo sapiens 160000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253260&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568997 104105826 CHEMBL493722 C01960 ZINC40431316 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433893 CN[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)22-16(29)10(6-13(26)27)20-17(30)11(7-23)21-15(28)9(19-3)4-5-12(24)25/h8-11,14,19,23H,4-7H2,1-3H3,(H,20,30)(H,21,28)(H,22,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 YGZHTJCMFNVSDW-RMIALFOJSA-N 50253223 (S)-5-((S)-1-((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-oxopropan-2-ylamino)-4-(methylamino)-5-oxopentanoic acid::CHEMBL523665 Disks large homolog 4 Homo sapiens 15000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253223&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568992 104105809 CHEMBL523665 ZINC40423006 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50433894 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O InChI=1S/C18H30N4O10/c1-8(2)14(18(31)32)21-16(29)11(6-13(26)27)22(3)17(30)10(7-23)20-15(28)9(19)4-5-12(24)25/h8-11,14,23H,4-7,19H2,1-3H3,(H,20,28)(H,21,29)(H,24,25)(H,26,27)(H,31,32)/t9-,10-,11-,14-/m0/s1 YTNSANDMIXPEOB-RMIALFOJSA-N 50253222 (S)-4-amino-5-((S)-1-(((S)-3-carboxy-1-((S)-1-carboxy-2-methylpropylamino)-1-oxopropan-2-yl)(methyl)amino)-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL492272 Disks large homolog 4 Homo sapiens 78000 ChEMBL 10.1021/jm800836w 10.7270/Q22807FQ 18811137 Bach, A; Chi, CN; Olsen, TB; Pedersen, SW; Roder, MU; Pang, GF; Clausen, RP; Jemth, P; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253222&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568990 104105808 CHEMBL492272 ZINC45498658 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921889 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H45N5O7/c1-14(2)20(25(36)37)29-22(33)15(3)28-24(35)21(16(4)31)30-23(34)18(10-11-19(26)32)27-13-12-17-8-6-5-7-9-17/h14-18,20-21,27,31H,5-13H2,1-4H3,(H2,26,32)(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t15-,16+,18-,20-,21-/m0/s1 VEURJCLHYDUHII-OKSLILNBSA-N 50339537 (4S,7S,10S,13S)-4-(3-amino-3-oxopropyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-10,14-dimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688607 Disks large homolog 4 Homo sapiens 141000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339537&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349855 125089639 CHEMBL1688607 ZINC66113788 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921890 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C23H42N4O6/c1-13(2)18(23(32)33)26-21(30)15(4)25-22(31)19(16(5)28)27-20(29)14(3)24-12-11-17-9-7-6-8-10-17/h13-19,24,28H,6-12H2,1-5H3,(H,25,31)(H,26,30)(H,27,29)(H,32,33)/t14-,15-,16+,18-,19-/m0/s1 DNBUGSJGXQUZHI-KWWJQKEASA-N 50339538 (4S,7S,10S,13S)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-4,10,14-trimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688609 Disks large homolog 4 Homo sapiens 89000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339538&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349857 125089640 CHEMBL1688609 ZINC66114148 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921891 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C24H42N4O8/c1-13(2)19(24(35)36)27-22(33)17(12-18(30)31)26-23(34)20(15(4)29)28-21(32)14(3)25-11-10-16-8-6-5-7-9-16/h13-17,19-20,25,29H,5-12H2,1-4H3,(H,26,34)(H,27,33)(H,28,32)(H,30,31)(H,35,36)/t14-,15+,17-,19-,20-/m0/s1 LWWNAOSECPVSOZ-SSGANFLRSA-N 50339539 (4S,7S,10S,13S)-10-(carboxymethyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-4,14-dimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688610 Disks large homolog 4 Homo sapiens >400000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339539&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349985 125089641 CHEMBL1688610 ZINC66123526 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921892 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 APPLGLBBZPGQBX-GDEPEFMTSA-N 50252827 CHEMBL493688::N-Cyclohexylethyl-ETAV Disks large homolog 4 Homo sapiens 630 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252827&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568836 104105553 CHEMBL493688 ZINC49881697 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921893 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(O)=O InChI=1S/C17H31N5O7/c1-7(2)12(17(28)29)21-14(25)8(3)20-16(27)13(9(4)23)22-15(26)10(18)5-6-11(19)24/h7-10,12-13,23H,5-6,18H2,1-4H3,(H2,19,24)(H,20,27)(H,21,25)(H,22,26)(H,28,29)/t8-,9+,10-,12-,13-/m0/s1 LWAFQPNXVVSTEM-WKLONVCASA-N 50339541 CHEMBL1688602::QTAV Disks large homolog 4 Homo sapiens 110000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339541&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349723 125089643 CHEMBL1688602 C01960 ZINC66114588 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921894 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(O)=O InChI=1S/C18H31N5O9/c1-7(2)13(18(31)32)22-16(29)10(6-12(26)27)21-17(30)14(8(3)24)23-15(28)9(19)4-5-11(20)25/h7-10,13-14,24H,4-6,19H2,1-3H3,(H2,20,25)(H,21,30)(H,22,29)(H,23,28)(H,26,27)(H,31,32)/t8-,9+,10+,13+,14+/m1/s1 YEWGGJQZPIGESX-PREJHDKISA-N 50339542 CHEMBL1688603::QTDV Disks large homolog 4 Homo sapiens 60000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339542&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349724 125089644 CHEMBL1688603 C01960 ZINC66112378 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921895 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(O)=O InChI=1S/C15H28N4O6/c1-6(2)10(15(24)25)18-13(22)8(4)17-14(23)11(9(5)20)19-12(21)7(3)16/h6-11,20H,16H2,1-5H3,(H,17,23)(H,18,22)(H,19,21)(H,24,25)/t7-,8-,9+,10-,11-/m0/s1 BKXWOKWUYWQWND-HHKYUTTNSA-N 50339543 ATAV::CHEMBL1688604 Disks large homolog 4 Homo sapiens 73000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339543&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349725 125089645 CHEMBL1688604 C01960 ZINC66114399 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921896 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(O)=O InChI=1S/C16H28N4O8/c1-6(2)11(16(27)28)19-14(25)9(5-10(22)23)18-15(26)12(8(4)21)20-13(24)7(3)17/h6-9,11-12,21H,5,17H2,1-4H3,(H,18,26)(H,19,25)(H,20,24)(H,22,23)(H,27,28)/t7-,8+,9-,11-,12-/m0/s1 SBSGEUBHXXHNBQ-RWRJDSDZSA-N 50339544 ATDV::CHEMBL1688605 Disks large homolog 4 Homo sapiens 38000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339544&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349853 125089646 CHEMBL1688605 C01960 ZINC66157501 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921897 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C26H44N4O10/c1-14(2)21(26(39)40)29-24(37)18(13-20(34)35)28-25(38)22(15(3)31)30-23(36)17(9-10-19(32)33)27-12-11-16-7-5-4-6-8-16/h14-18,21-22,27,31H,4-13H2,1-3H3,(H,28,38)(H,29,37)(H,30,36)(H,32,33)(H,34,35)(H,39,40)/t15-,17+,18+,21+,22+/m1/s1 BFQMAHJQYPUTAW-LWHBNQIPSA-N 50339545 (4S,7S,10S,13S)-4-(2-carboxyethyl)-10-(carboxymethyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-14-methyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688606 Disks large homolog 4 Homo sapiens 750 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339545&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349854 125089647 CHEMBL1688606 ZINC66113786 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921898 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H45N5O7/c1-14(2)20(25(36)37)29-22(33)15(3)28-24(35)21(16(4)31)30-23(34)18(10-11-19(26)32)27-13-12-17-8-6-5-7-9-17/h14-18,20-21,27,31H,5-13H2,1-4H3,(H2,26,32)(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t15-,16+,18-,20-,21-/m0/s1 VEURJCLHYDUHII-OKSLILNBSA-N 50339537 (4S,7S,10S,13S)-4-(3-amino-3-oxopropyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-10,14-dimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688607 Disks large homolog 4 Homo sapiens 12000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339537&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349855 125089639 CHEMBL1688607 ZINC66113788 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921899 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C26H45N5O9/c1-14(2)21(26(39)40)30-24(37)18(13-20(34)35)29-25(38)22(15(3)32)31-23(36)17(9-10-19(27)33)28-12-11-16-7-5-4-6-8-16/h14-18,21-22,28,32H,4-13H2,1-3H3,(H2,27,33)(H,29,38)(H,30,37)(H,31,36)(H,34,35)(H,39,40)/t15-,17+,18+,21+,22+/m1/s1 AHDIVQMUAPWRPL-LWHBNQIPSA-N 50339546 (4S,7S,10S,13S)-4-(3-amino-3-oxopropyl)-10-(carboxymethyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-14-methyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688608 Disks large homolog 4 Homo sapiens 4400 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339546&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349856 125089648 CHEMBL1688608 ZINC66113789 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921900 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C23H42N4O6/c1-13(2)18(23(32)33)26-21(30)15(4)25-22(31)19(16(5)28)27-20(29)14(3)24-12-11-17-9-7-6-8-10-17/h13-19,24,28H,6-12H2,1-5H3,(H,25,31)(H,26,30)(H,27,29)(H,32,33)/t14-,15-,16+,18-,19-/m0/s1 DNBUGSJGXQUZHI-KWWJQKEASA-N 50339538 (4S,7S,10S,13S)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-4,10,14-trimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688609 Disks large homolog 4 Homo sapiens 8100 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339538&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349857 125089640 CHEMBL1688609 ZINC66114148 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921901 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C24H42N4O8/c1-13(2)19(24(35)36)27-22(33)17(12-18(30)31)26-23(34)20(15(4)29)28-21(32)14(3)25-11-10-16-8-6-5-7-9-16/h13-17,19-20,25,29H,5-12H2,1-4H3,(H,26,34)(H,27,33)(H,28,32)(H,30,31)(H,35,36)/t14-,15+,17-,19-,20-/m0/s1 LWWNAOSECPVSOZ-SSGANFLRSA-N 50339539 (4S,7S,10S,13S)-10-(carboxymethyl)-1-cyclohexyl-7-((R)-1-hydroxyethyl)-4,14-dimethyl-5,8,11-trioxo-3,6,9,12-tetraazapentadecane-13-carboxylic acid::CHEMBL1688610 Disks large homolog 4 Homo sapiens 3600 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339539&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349985 125089641 CHEMBL1688610 ZINC66123526 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921902 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C30H40N4O10/c1-16(2)25(30(43)44)33-28(41)22(15-24(38)39)32-29(42)26(17(3)35)34-27(40)21(10-11-23(36)37)31-13-12-18-8-9-19-6-4-5-7-20(19)14-18/h4-9,14,16-17,21-22,25-26,31,35H,10-13,15H2,1-3H3,(H,32,42)(H,33,41)(H,34,40)(H,36,37)(H,38,39)(H,43,44)/t17-,21+,22+,25+,26+/m1/s1 CFXOTPMOVZBOSR-OLWWZTHPSA-N 50339547 (2S,5S,8S,11S)-11-(2-carboxyethyl)-5-(carboxymethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-14-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688611 Disks large homolog 4 Homo sapiens 1800 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339547&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349986 125089649 CHEMBL1688611 ZINC66123693 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921903 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C26H36Cl2N4O10/c1-12(2)21(26(41)42)31-24(39)18(11-20(36)37)30-25(40)22(13(3)33)32-23(38)17(6-7-19(34)35)29-9-8-14-4-5-15(27)16(28)10-14/h4-5,10,12-13,17-18,21-22,29,33H,6-9,11H2,1-3H3,(H,30,40)(H,31,39)(H,32,38)(H,34,35)(H,36,37)(H,41,42)/t13-,17+,18+,21+,22+/m1/s1 HZZSXRUPCNVCCP-AVRJIPIDSA-N 50339548 (2S,5S,8S,11S)-11-(2-carboxyethyl)-5-(carboxymethyl)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688612 Disks large homolog 4 Homo sapiens 1200 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339548&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349987 125089650 CHEMBL1688612 ZINC72127021 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921904 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C27H38N4O6/c1-15(2)22(27(36)37)30-25(34)17(4)29-26(35)23(18(5)32)31-24(33)16(3)28-13-12-19-10-11-20-8-6-7-9-21(20)14-19/h6-11,14-18,22-23,28,32H,12-13H2,1-5H3,(H,29,35)(H,30,34)(H,31,33)(H,36,37)/t16-,17-,18+,22-,23-/m0/s1 QRCFCQUGTHASOJ-NGAGVGIASA-N 50339549 (2S,5S,8S,11S)-8-((R)-1-hydroxyethyl)-2-isopropyl-5,11-dimethyl-14-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688613 Disks large homolog 4 Homo sapiens 56000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339549&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349988 125089651 CHEMBL1688613 ZINC66114028 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921905 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C23H34Cl2N4O6/c1-11(2)18(23(34)35)28-21(32)13(4)27-22(33)19(14(5)30)29-20(31)12(3)26-9-8-15-6-7-16(24)17(25)10-15/h6-7,10-14,18-19,26,30H,8-9H2,1-5H3,(H,27,33)(H,28,32)(H,29,31)(H,34,35)/t12-,13-,14+,18-,19-/m0/s1 HSOUWWPIGTVTAZ-YEAPKDELSA-N 50339550 (2S,5S,8S,11S)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5,11-dimethyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688614 Disks large homolog 4 Homo sapiens 13000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339550&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349989 125089652 CHEMBL1688614 ZINC66114031 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921906 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC12CC3CC(CC(C3)C1)C2)[C@@H](C)O)C(O)=O InChI=1S/C28H46N4O8/c1-14(2)22(27(39)40)31-24(36)15(3)30-26(38)23(16(4)33)32-25(37)20(5-6-21(34)35)29-13-28-10-17-7-18(11-28)9-19(8-17)12-28/h14-20,22-23,29,33H,5-13H2,1-4H3,(H,30,38)(H,31,36)(H,32,37)(H,34,35)(H,39,40)/t15-,16+,17?,18?,19?,20-,22-,23-,28?/m0/s1 NRUQVLGGFUPVOF-SPEQUKJNSA-N 50339551 (S)-2-[(S)-2-((2S,3R)-2-{(S)-2-[(Adamantan-1-ylmethyl)-amino]-4-carboxy-butyrylamino}-3-hydroxy-butyrylamino)-propionylamino]-3-methyl-butyric acid::CHEMBL1688615 Disks large homolog 4 Homo sapiens 2100 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339551&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53324180 125089653 CHEMBL1688615 ZINC66111921 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921907 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CC2CCC1C2)[C@@H](C)O)C(O)=O InChI=1S/C25H42N4O8/c1-12(2)20(25(36)37)28-22(33)13(3)27-24(35)21(14(4)30)29-23(34)18(7-8-19(31)32)26-11-17-10-15-5-6-16(17)9-15/h12-18,20-21,26,30H,5-11H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t13-,14+,15?,16?,17?,18-,20-,21-/m0/s1 SPSXGQDIJAFKPQ-LTIPZMNHSA-N 50339552 (3S,6S,9S,12S)-1-(bicyclo[2.2.1]heptan-2-yl)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7,10-trioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688616 Disks large homolog 4 Homo sapiens 1300 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339552&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53326546 125089654 CHEMBL1688616 ZINC66112147 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921908 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CC2CCC1C2)[C@@H](C)O)C(O)=O InChI=1S/C26H44N4O8/c1-13(2)21(26(37)38)29-23(34)14(3)28-25(36)22(15(4)31)30-24(35)19(7-8-20(32)33)27-10-9-18-12-16-5-6-17(18)11-16/h13-19,21-22,27,31H,5-12H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t14-,15+,16?,17?,18?,19-,21-,22-/m0/s1 BQLARHIUYSAOHF-QKDVZYMOSA-N 50339553 (2S,5S,8S,11S)-14-(bicyclo[2.2.1]heptan-2-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688617 Disks large homolog 4 Homo sapiens 1500 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339553&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53322961 125089655 CHEMBL1688617 ZINC66112149 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921909 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CCCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(11-12-19(31)32)26-13-17-9-7-5-6-8-10-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16+,18-,20-,21-/m0/s1 YDFKAYXCBSTKHR-OKSLILNBSA-N 50339554 (3S,6S,9S,12S)-3-(2-carboxyethyl)-1-cycloheptyl-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7,10-trioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688618 Disks large homolog 4 Homo sapiens 1400 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339554&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350132 125089656 CHEMBL1688618 ZINC66112150 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921910 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C26H46N4O8/c1-15(2)21(26(37)38)29-23(34)16(3)28-25(36)22(17(4)31)30-24(35)19(11-12-20(32)33)27-14-13-18-9-7-5-6-8-10-18/h15-19,21-22,27,31H,5-14H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t16-,17+,19-,21-,22-/m0/s1 UDNHSVSPBAEXPM-KOLYYURTSA-N 50339555 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-cycloheptyl-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688619 Disks large homolog 4 Homo sapiens 1200 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339555&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350133 125089657 CHEMBL1688619 ZINC66112151 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921911 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(F)c(F)c1F)[C@@H](C)O)C(O)=O InChI=1S/C25H35F3N4O8/c1-11(2)20(25(39)40)31-22(36)12(3)30-24(38)21(13(4)33)32-23(37)16(7-8-17(34)35)29-10-9-14-5-6-15(26)19(28)18(14)27/h5-6,11-13,16,20-21,29,33H,7-10H2,1-4H3,(H,30,38)(H,31,36)(H,32,37)(H,34,35)(H,39,40)/t12-,13+,16-,20-,21-/m0/s1 GNIWGABHLSLATO-PVMQWSNJSA-N 50339556 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-14-(2,3,4-trifluorophenyl)-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688620 Disks large homolog 4 Homo sapiens 1800 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339556&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350266 125089658 CHEMBL1688620 ZINC66114464 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921912 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccc(F)c(F)c1F)[C@@H](C)O)C(O)=O InChI=1S/C26H37F3N4O8/c1-12(2)21(26(40)41)32-23(37)13(3)31-25(39)22(14(4)34)33-24(38)17(9-10-18(35)36)30-11-5-6-15-7-8-16(27)20(29)19(15)28/h7-8,12-14,17,21-22,30,34H,5-6,9-11H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)(H,35,36)(H,40,41)/t13-,14+,17-,21-,22-/m0/s1 CLNFYZXZEPWINZ-ZTYQMOJCSA-N 50339557 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-15-(2,3,4-trifluorophenyl)-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688621 Disks large homolog 4 Homo sapiens 4200 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339557&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350267 125089659 CHEMBL1688621 ZINC66122803 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921913 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C30H42N4O8/c1-17(2)25(30(41)42)33-27(38)18(3)32-29(40)26(19(4)35)34-28(39)23(13-14-24(36)37)31-15-7-8-20-11-12-21-9-5-6-10-22(21)16-20/h5-6,9-12,16-19,23,25-26,31,35H,7-8,13-15H2,1-4H3,(H,32,40)(H,33,38)(H,34,39)(H,36,37)(H,41,42)/t18-,19+,23-,25-,26-/m0/s1 UQHFYOATKGJEBF-BRQKXJLLSA-N 50339558 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-15-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688622 Disks large homolog 4 Homo sapiens 5000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339558&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350268 125089660 CHEMBL1688622 ZINC66122805 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921914 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1c2ccccc2cc2ccccc12)[C@@H](C)O)C(O)=O InChI=1S/C33H42N4O8/c1-18(2)28(33(44)45)36-30(41)19(3)35-32(43)29(20(4)38)37-31(42)26(13-14-27(39)40)34-16-15-25-23-11-7-5-9-21(23)17-22-10-6-8-12-24(22)25/h5-12,17-20,26,28-29,34,38H,13-16H2,1-4H3,(H,35,43)(H,36,41)(H,37,42)(H,39,40)(H,44,45)/t19-,20+,26-,28-,29-/m0/s1 PHJJJMRUGBXMNH-PGZSINSQSA-N 50339559 (2S,5S,8S,11S)-14-(anthracen-9-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688623 Disks large homolog 4 Homo sapiens 9700 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339559&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350269 125089661 CHEMBL1688623 ZINC66122806 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921915 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1c2ccccc2cc2ccccc12)[C@@H](C)O)C(O)=O InChI=1S/C34H44N4O8/c1-19(2)29(34(45)46)37-31(42)20(3)36-33(44)30(21(4)39)38-32(43)27(15-16-28(40)41)35-17-9-14-26-24-12-7-5-10-22(24)18-23-11-6-8-13-25(23)26/h5-8,10-13,18-21,27,29-30,35,39H,9,14-17H2,1-4H3,(H,36,44)(H,37,42)(H,38,43)(H,40,41)(H,45,46)/t20-,21+,27-,29-,30-/m0/s1 WQNAIFKZOSUNID-LKJHYFBTSA-N 50339560 (2S,5S,8S,11S)-15-(anthracen-9-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688624 Disks large homolog 4 Homo sapiens 9000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339560&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350401 125089662 CHEMBL1688624 ZINC72126777 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921916 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccc3cccc4ccc1c2c34)[C@@H](C)O)C(O)=O InChI=1S/C35H42N4O8/c1-18(2)30(35(46)47)38-32(43)19(3)37-34(45)31(20(4)40)39-33(44)26(14-15-27(41)42)36-17-16-21-8-9-24-11-10-22-6-5-7-23-12-13-25(21)29(24)28(22)23/h5-13,18-20,26,30-31,36,40H,14-17H2,1-4H3,(H,37,45)(H,38,43)(H,39,44)(H,41,42)(H,46,47)/t19-,20+,26-,30-,31-/m0/s1 XMTPXACLDZCBPY-SSKZLDDGSA-N 50339561 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-14-(pyren-1-yl)-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688625 Disks large homolog 4 Homo sapiens 16000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339561&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350402 125089663 CHEMBL1688625 ZINC72126778 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921917 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCCc1ccc2ccc3cccc4ccc1c2c34)[C@@H](C)O)C(O)=O InChI=1S/C37H46N4O8/c1-20(2)32(37(48)49)40-34(45)21(3)39-36(47)33(22(4)42)41-35(46)28(17-18-29(43)44)38-19-6-5-8-23-11-12-26-14-13-24-9-7-10-25-15-16-27(23)31(26)30(24)25/h7,9-16,20-22,28,32-33,38,42H,5-6,8,17-19H2,1-4H3,(H,39,47)(H,40,45)(H,41,46)(H,43,44)(H,48,49)/t21-,22+,28-,32-,33-/m0/s1 JKZSRFKLNYPPDJ-HUUSFFTHSA-N 50339562 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-16-(pyren-1-yl)-3,6,9,12-tetraazahexadecan-1-oic acid::CHEMBL1688626 Disks large homolog 4 Homo sapiens 33000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339562&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350403 125089664 CHEMBL1688626 ZINC72126779 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921918 CN[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O8/c1-8(2)13(18(29)30)21-15(26)9(3)20-17(28)14(10(4)23)22-16(27)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,28)(H,21,26)(H,22,27)(H,24,25)(H,29,30)/t9-,10+,11-,13-,14-/m0/s1 LOKBVOQPMLVOAY-WTNWGCMGSA-N 50339563 (3S,6S,9S,12S)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7,10-trioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688627 Disks large homolog 4 Homo sapiens 9650 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339563&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 25133600 125089665 CHEMBL1688627 ZINC40428769 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921919 CN[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=S)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O7S/c1-8(2)13(18(28)29)22-17(30)9(3)20-16(27)14(10(4)23)21-15(26)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,27)(H,21,26)(H,22,30)(H,24,25)(H,28,29)/t9-,10+,11-,13-,14-/m0/s1 VDXQDDDGHXNQIL-WTNWGCMGSA-N 50339564 (3S,6S,9S,12S)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7-dioxo-10-thioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688628 Disks large homolog 4 Homo sapiens 10800 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339564&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350544 125089666 CHEMBL1688628 ZINC66111595 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921920 CN[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=S)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O7S/c1-8(2)13(18(28)29)21-15(26)9(3)20-17(30)14(10(4)23)22-16(27)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,30)(H,21,26)(H,22,27)(H,24,25)(H,28,29)/t9-,10+,11-,13-,14-/m0/s1 LLGIRDXPUOIBDJ-WTNWGCMGSA-N 50339565 (3S,6S,9S,12S)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,10-dioxo-7-thioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688629 Disks large homolog 4 Homo sapiens 220000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339565&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350671 125089667 CHEMBL1688629 ZINC66122980 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921921 CN[C@@H](CCC(O)=O)C(=S)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H32N4O7S/c1-8(2)13(18(28)29)21-15(26)9(3)20-16(27)14(10(4)23)22-17(30)11(19-5)6-7-12(24)25/h8-11,13-14,19,23H,6-7H2,1-5H3,(H,20,27)(H,21,26)(H,22,30)(H,24,25)(H,28,29)/t9-,10+,11-,13-,14-/m0/s1 PIHVBZSTKQZTFB-WTNWGCMGSA-N 50339566 (3S,6S,9S,12S)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-7,10-dioxo-4-thioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688630 Disks large homolog 4 Homo sapiens 32000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339566&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350797 125089668 CHEMBL1688630 ZINC66122982 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921922 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H44N4O7S/c1-14(2)20(25(35)36)29-24(37)15(3)27-23(34)21(16(4)30)28-22(33)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,34)(H,28,33)(H,29,37)(H,31,32)(H,35,36)/t15-,16+,18-,20-,21-/m0/s1 XVBZEYLAAISIDP-OKSLILNBSA-N 50339567 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-cyclohexyl-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688631 Disks large homolog 4 Homo sapiens 630 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339567&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350908 125089669 CHEMBL1688631 ZINC66114417 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921923 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C29H40N4O7S/c1-16(2)24(29(39)40)33-28(41)17(3)31-27(38)25(18(4)34)32-26(37)22(11-12-23(35)36)30-14-13-19-9-10-20-7-5-6-8-21(20)15-19/h5-10,15-18,22,24-25,30,34H,11-14H2,1-4H3,(H,31,38)(H,32,37)(H,33,41)(H,35,36)(H,39,40)/t17-,18+,22-,24-,25-/m0/s1 NISYTZQXMHYJCD-VFFNRDDGSA-N 50339568 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-14-(naphthalen-2-yl)-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688632 Disks large homolog 4 Homo sapiens 1100 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339568&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350909 125089670 CHEMBL1688632 ZINC66114418 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921924 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C25H36Cl2N4O7S/c1-12(2)20(25(37)38)31-24(39)13(3)29-23(36)21(14(4)32)30-22(35)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,36)(H,30,35)(H,31,39)(H,33,34)(H,37,38)/t13-,14+,18-,20-,21-/m0/s1 MQVRLOSWHOLIPR-QAJIRISXSA-N 50339569 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688633 Disks large homolog 4 Homo sapiens 1000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339569&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350910 125089671 CHEMBL1688633 ZINC66114421 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921925 CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C105H188N42O30/c1-7-55(6)80(98(175)140-69(34-36-77(154)155)92(169)143-72(50-148)95(172)142-71(48-78(156)157)94(171)146-79(54(4)5)99(176)177)147-97(174)74(52-150)145-96(173)73(51-149)144-93(170)70(46-53(2)3)141-90(167)62(22-10-13-39-108)133-85(162)63(24-15-41-124-101(113)114)135-87(164)65(26-17-43-126-103(117)118)136-88(165)66(27-18-44-127-104(119)120)138-91(168)68(33-35-75(110)152)139-89(166)67(28-19-45-128-105(121)122)137-86(163)64(25-16-42-125-102(115)116)134-84(161)61(21-9-12-38-107)132-83(160)60(20-8-11-37-106)131-82(159)59(23-14-40-123-100(111)112)130-76(153)49-129-81(158)58(109)47-56-29-31-57(151)32-30-56/h29-32,53-55,58-74,79-80,148-151H,7-28,33-52,106-109H2,1-6H3,(H2,110,152)(H,129,158)(H,130,153)(H,131,159)(H,132,160)(H,133,162)(H,134,161)(H,135,164)(H,136,165)(H,137,163)(H,138,168)(H,139,166)(H,140,175)(H,141,167)(H,142,172)(H,143,169)(H,144,170)(H,145,173)(H,146,171)(H,147,174)(H,154,155)(H,156,157)(H,176,177)(H4,111,112,123)(H4,113,114,124)(H4,115,116,125)(H4,117,118,126)(H4,119,120,127)(H4,121,122,128)/t55-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,79-,80-/m0/s1 XWQVQFBTSBCKLI-FKXNDIMNSA-N 50253145 CHEMBL502630::YGRKKRRQRRR-KLSSIESDV Disks large homolog 4 Homo sapiens 4400 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253145&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 91935893 104105744 CHEMBL502630 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921926 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)C(C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16?,18-,20-,21-/m0/s1 APPLGLBBZPGQBX-GDEPEFMTSA-N 50252827 CHEMBL493688::N-Cyclohexylethyl-ETAV Disks large homolog 4 Homo sapiens 11000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252827&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 44568836 104105553 CHEMBL493688 ZINC49881697 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921927 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(O)=O InChI=1S/C17H31N5O7/c1-7(2)12(17(28)29)21-14(25)8(3)20-16(27)13(9(4)23)22-15(26)10(18)5-6-11(19)24/h7-10,12-13,23H,5-6,18H2,1-4H3,(H2,19,24)(H,20,27)(H,21,25)(H,22,26)(H,28,29)/t8-,9+,10-,12-,13-/m0/s1 LWAFQPNXVVSTEM-WKLONVCASA-N 50339541 CHEMBL1688602::QTAV Disks large homolog 4 Homo sapiens >400000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339541&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349723 125089643 CHEMBL1688602 C01960 ZINC66114588 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921928 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(O)=O InChI=1S/C15H28N4O6/c1-6(2)10(15(24)25)18-13(22)8(4)17-14(23)11(9(5)20)19-12(21)7(3)16/h6-11,20H,16H2,1-5H3,(H,17,23)(H,18,22)(H,19,21)(H,24,25)/t7-,8-,9+,10-,11-/m0/s1 BKXWOKWUYWQWND-HHKYUTTNSA-N 50339543 ATAV::CHEMBL1688604 Disks large homolog 4 Homo sapiens >400000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339543&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349725 125089645 CHEMBL1688604 C01960 ZINC66114399 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921929 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C30H40N4O10/c1-16(2)25(30(43)44)33-28(41)22(15-24(38)39)32-29(42)26(17(3)35)34-27(40)21(10-11-23(36)37)31-13-12-18-8-9-19-6-4-5-7-20(19)14-18/h4-9,14,16-17,21-22,25-26,31,35H,10-13,15H2,1-3H3,(H,32,42)(H,33,41)(H,34,40)(H,36,37)(H,38,39)(H,43,44)/t17-,21+,22+,25+,26+/m1/s1 CFXOTPMOVZBOSR-OLWWZTHPSA-N 50339547 (2S,5S,8S,11S)-11-(2-carboxyethyl)-5-(carboxymethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-14-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688611 Disks large homolog 4 Homo sapiens 210000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339547&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349986 125089649 CHEMBL1688611 ZINC66123693 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921930 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C26H36Cl2N4O10/c1-12(2)21(26(41)42)31-24(39)18(11-20(36)37)30-25(40)22(13(3)33)32-23(38)17(6-7-19(34)35)29-9-8-14-4-5-15(27)16(28)10-14/h4-5,10,12-13,17-18,21-22,29,33H,6-9,11H2,1-3H3,(H,30,40)(H,31,39)(H,32,38)(H,34,35)(H,36,37)(H,41,42)/t13-,17+,18+,21+,22+/m1/s1 HZZSXRUPCNVCCP-AVRJIPIDSA-N 50339548 (2S,5S,8S,11S)-11-(2-carboxyethyl)-5-(carboxymethyl)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688612 Disks large homolog 4 Homo sapiens 130000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339548&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349987 125089650 CHEMBL1688612 ZINC72127021 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921931 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C27H38N4O6/c1-15(2)22(27(36)37)30-25(34)17(4)29-26(35)23(18(5)32)31-24(33)16(3)28-13-12-19-10-11-20-8-6-7-9-21(20)14-19/h6-11,14-18,22-23,28,32H,12-13H2,1-5H3,(H,29,35)(H,30,34)(H,31,33)(H,36,37)/t16-,17-,18+,22-,23-/m0/s1 QRCFCQUGTHASOJ-NGAGVGIASA-N 50339549 (2S,5S,8S,11S)-8-((R)-1-hydroxyethyl)-2-isopropyl-5,11-dimethyl-14-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688613 Disks large homolog 4 Homo sapiens 280000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339549&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349988 125089651 CHEMBL1688613 ZINC66114028 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921932 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C23H34Cl2N4O6/c1-11(2)18(23(34)35)28-21(32)13(4)27-22(33)19(14(5)30)29-20(31)12(3)26-9-8-15-6-7-16(24)17(25)10-15/h6-7,10-14,18-19,26,30H,8-9H2,1-5H3,(H,27,33)(H,28,32)(H,29,31)(H,34,35)/t12-,13-,14+,18-,19-/m0/s1 HSOUWWPIGTVTAZ-YEAPKDELSA-N 50339550 (2S,5S,8S,11S)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5,11-dimethyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688614 Disks large homolog 4 Homo sapiens 64000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339550&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51349989 125089652 CHEMBL1688614 ZINC66114031 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921933 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC12CC3CC(CC(C3)C1)C2)[C@@H](C)O)C(O)=O InChI=1S/C28H46N4O8/c1-14(2)22(27(39)40)31-24(36)15(3)30-26(38)23(16(4)33)32-25(37)20(5-6-21(34)35)29-13-28-10-17-7-18(11-28)9-19(8-17)12-28/h14-20,22-23,29,33H,5-13H2,1-4H3,(H,30,38)(H,31,36)(H,32,37)(H,34,35)(H,39,40)/t15-,16+,17?,18?,19?,20-,22-,23-,28?/m0/s1 NRUQVLGGFUPVOF-SPEQUKJNSA-N 50339551 (S)-2-[(S)-2-((2S,3R)-2-{(S)-2-[(Adamantan-1-ylmethyl)-amino]-4-carboxy-butyrylamino}-3-hydroxy-butyrylamino)-propionylamino]-3-methyl-butyric acid::CHEMBL1688615 Disks large homolog 4 Homo sapiens 6700 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339551&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53324180 125089653 CHEMBL1688615 ZINC66111921 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921934 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CC2CCC1C2)[C@@H](C)O)C(O)=O InChI=1S/C25H42N4O8/c1-12(2)20(25(36)37)28-22(33)13(3)27-24(35)21(14(4)30)29-23(34)18(7-8-19(31)32)26-11-17-10-15-5-6-16(17)9-15/h12-18,20-21,26,30H,5-11H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t13-,14+,15?,16?,17?,18-,20-,21-/m0/s1 SPSXGQDIJAFKPQ-LTIPZMNHSA-N 50339552 (3S,6S,9S,12S)-1-(bicyclo[2.2.1]heptan-2-yl)-3-(2-carboxyethyl)-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7,10-trioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688616 Disks large homolog 4 Homo sapiens 20000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339552&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53326546 125089654 CHEMBL1688616 ZINC66112147 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921935 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CC2CCC1C2)[C@@H](C)O)C(O)=O InChI=1S/C26H44N4O8/c1-13(2)21(26(37)38)29-23(34)14(3)28-25(36)22(15(4)31)30-24(35)19(7-8-20(32)33)27-10-9-18-12-16-5-6-17(18)11-16/h13-19,21-22,27,31H,5-12H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t14-,15+,16?,17?,18?,19-,21-,22-/m0/s1 BQLARHIUYSAOHF-QKDVZYMOSA-N 50339553 (2S,5S,8S,11S)-14-(bicyclo[2.2.1]heptan-2-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688617 Disks large homolog 4 Homo sapiens 14000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339553&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 53322961 125089655 CHEMBL1688617 ZINC66112149 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921936 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCC1CCCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H44N4O8/c1-14(2)20(25(36)37)28-22(33)15(3)27-24(35)21(16(4)30)29-23(34)18(11-12-19(31)32)26-13-17-9-7-5-6-8-10-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)/t15-,16+,18-,20-,21-/m0/s1 YDFKAYXCBSTKHR-OKSLILNBSA-N 50339554 (3S,6S,9S,12S)-3-(2-carboxyethyl)-1-cycloheptyl-6-((R)-1-hydroxyethyl)-12-isopropyl-9-methyl-4,7,10-trioxo-2,5,8,11-tetraazatridecan-13-oic acid::CHEMBL1688618 Disks large homolog 4 Homo sapiens 16000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339554&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350132 125089656 CHEMBL1688618 ZINC66112150 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921937 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C26H46N4O8/c1-15(2)21(26(37)38)29-23(34)16(3)28-25(36)22(17(4)31)30-24(35)19(11-12-20(32)33)27-14-13-18-9-7-5-6-8-10-18/h15-19,21-22,27,31H,5-14H2,1-4H3,(H,28,36)(H,29,34)(H,30,35)(H,32,33)(H,37,38)/t16-,17+,19-,21-,22-/m0/s1 UDNHSVSPBAEXPM-KOLYYURTSA-N 50339555 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-cycloheptyl-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688619 Disks large homolog 4 Homo sapiens 9400 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339555&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350133 125089657 CHEMBL1688619 ZINC66112151 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921938 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(F)c(F)c1F)[C@@H](C)O)C(O)=O InChI=1S/C25H35F3N4O8/c1-11(2)20(25(39)40)31-22(36)12(3)30-24(38)21(13(4)33)32-23(37)16(7-8-17(34)35)29-10-9-14-5-6-15(26)19(28)18(14)27/h5-6,11-13,16,20-21,29,33H,7-10H2,1-4H3,(H,30,38)(H,31,36)(H,32,37)(H,34,35)(H,39,40)/t12-,13+,16-,20-,21-/m0/s1 GNIWGABHLSLATO-PVMQWSNJSA-N 50339556 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-14-(2,3,4-trifluorophenyl)-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688620 Disks large homolog 4 Homo sapiens 8800 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339556&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350266 125089658 CHEMBL1688620 ZINC66114464 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921939 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccc(F)c(F)c1F)[C@@H](C)O)C(O)=O InChI=1S/C26H37F3N4O8/c1-12(2)21(26(40)41)32-23(37)13(3)31-25(39)22(14(4)34)33-24(38)17(9-10-18(35)36)30-11-5-6-15-7-8-16(27)20(29)19(15)28/h7-8,12-14,17,21-22,30,34H,5-6,9-11H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)(H,35,36)(H,40,41)/t13-,14+,17-,21-,22-/m0/s1 CLNFYZXZEPWINZ-ZTYQMOJCSA-N 50339557 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-15-(2,3,4-trifluorophenyl)-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688621 Disks large homolog 4 Homo sapiens 44000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339557&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350267 125089659 CHEMBL1688621 ZINC66122803 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921940 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C30H42N4O8/c1-17(2)25(30(41)42)33-27(38)18(3)32-29(40)26(19(4)35)34-28(39)23(13-14-24(36)37)31-15-7-8-20-11-12-21-9-5-6-10-22(21)16-20/h5-6,9-12,16-19,23,25-26,31,35H,7-8,13-15H2,1-4H3,(H,32,40)(H,33,38)(H,34,39)(H,36,37)(H,41,42)/t18-,19+,23-,25-,26-/m0/s1 UQHFYOATKGJEBF-BRQKXJLLSA-N 50339558 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-15-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688622 Disks large homolog 4 Homo sapiens 53000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339558&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350268 125089660 CHEMBL1688622 ZINC66122805 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921941 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1c2ccccc2cc2ccccc12)[C@@H](C)O)C(O)=O InChI=1S/C33H42N4O8/c1-18(2)28(33(44)45)36-30(41)19(3)35-32(43)29(20(4)38)37-31(42)26(13-14-27(39)40)34-16-15-25-23-11-7-5-9-21(23)17-22-10-6-8-12-24(22)25/h5-12,17-20,26,28-29,34,38H,13-16H2,1-4H3,(H,35,43)(H,36,41)(H,37,42)(H,39,40)(H,44,45)/t19-,20+,26-,28-,29-/m0/s1 PHJJJMRUGBXMNH-PGZSINSQSA-N 50339559 (2S,5S,8S,11S)-14-(anthracen-9-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688623 Disks large homolog 4 Homo sapiens 39000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339559&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350269 125089661 CHEMBL1688623 ZINC66122806 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921942 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCc1c2ccccc2cc2ccccc12)[C@@H](C)O)C(O)=O InChI=1S/C34H44N4O8/c1-19(2)29(34(45)46)37-31(42)20(3)36-33(44)30(21(4)39)38-32(43)27(15-16-28(40)41)35-17-9-14-26-24-12-7-5-10-22(24)18-23-11-6-8-13-25(23)26/h5-8,10-13,18-21,27,29-30,35,39H,9,14-17H2,1-4H3,(H,36,44)(H,37,42)(H,38,43)(H,40,41)(H,45,46)/t20-,21+,27-,29-,30-/m0/s1 WQNAIFKZOSUNID-LKJHYFBTSA-N 50339560 (2S,5S,8S,11S)-15-(anthracen-9-yl)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-3,6,9,12-tetraazapentadecan-1-oic acid::CHEMBL1688624 Disks large homolog 4 Homo sapiens 95000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339560&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350401 125089662 CHEMBL1688624 ZINC72126777 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921943 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccc3cccc4ccc1c2c34)[C@@H](C)O)C(O)=O InChI=1S/C35H42N4O8/c1-18(2)30(35(46)47)38-32(43)19(3)37-34(45)31(20(4)40)39-33(44)26(14-15-27(41)42)36-17-16-21-8-9-24-11-10-22-6-5-7-23-12-13-25(21)29(24)28(22)23/h5-13,18-20,26,30-31,36,40H,14-17H2,1-4H3,(H,37,45)(H,38,43)(H,39,44)(H,41,42)(H,46,47)/t19-,20+,26-,30-,31-/m0/s1 XMTPXACLDZCBPY-SSKZLDDGSA-N 50339561 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-14-(pyren-1-yl)-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688625 Disks large homolog 4 Homo sapiens 51000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339561&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350402 125089663 CHEMBL1688625 ZINC72126778 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921944 CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCCCc1ccc2ccc3cccc4ccc1c2c34)[C@@H](C)O)C(O)=O InChI=1S/C37H46N4O8/c1-20(2)32(37(48)49)40-34(45)21(3)39-36(47)33(22(4)42)41-35(46)28(17-18-29(43)44)38-19-6-5-8-23-11-12-26-14-13-24-9-7-10-25-15-16-27(23)31(26)30(24)25/h7,9-16,20-22,28,32-33,38,42H,5-6,8,17-19H2,1-4H3,(H,39,47)(H,40,45)(H,41,46)(H,43,44)(H,48,49)/t21-,22+,28-,32-,33-/m0/s1 JKZSRFKLNYPPDJ-HUUSFFTHSA-N 50339562 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-4,7,10-trioxo-16-(pyren-1-yl)-3,6,9,12-tetraazahexadecan-1-oic acid::CHEMBL1688626 Disks large homolog 4 Homo sapiens 76000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339562&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350403 125089664 CHEMBL1688626 ZINC72126779 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921945 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCC1CCCCC1)[C@@H](C)O)C(O)=O InChI=1S/C25H44N4O7S/c1-14(2)20(25(35)36)29-24(37)15(3)27-23(34)21(16(4)30)28-22(33)18(10-11-19(31)32)26-13-12-17-8-6-5-7-9-17/h14-18,20-21,26,30H,5-13H2,1-4H3,(H,27,34)(H,28,33)(H,29,37)(H,31,32)(H,35,36)/t15-,16+,18-,20-,21-/m0/s1 XVBZEYLAAISIDP-OKSLILNBSA-N 50339567 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-cyclohexyl-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688631 Disks large homolog 4 Homo sapiens 11000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339567&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350908 125089669 CHEMBL1688631 ZINC66114417 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921946 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O InChI=1S/C29H40N4O7S/c1-16(2)24(29(39)40)33-28(41)17(3)31-27(38)25(18(4)34)32-26(37)22(11-12-23(35)36)30-14-13-19-9-10-20-7-5-6-8-21(20)15-19/h5-10,15-18,22,24-25,30,34H,11-14H2,1-4H3,(H,31,38)(H,32,37)(H,33,41)(H,35,36)(H,39,40)/t17-,18+,22-,24-,25-/m0/s1 NISYTZQXMHYJCD-VFFNRDDGSA-N 50339568 (2S,5S,8S,11S)-11-(2-carboxyethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-14-(naphthalen-2-yl)-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688632 Disks large homolog 4 Homo sapiens 11000 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339568&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350909 125089670 CHEMBL1688632 ZINC66114418 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8 50921947 CC(C)[C@H](NC(=S)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc(Cl)c(Cl)c1)[C@@H](C)O)C(O)=O InChI=1S/C25H36Cl2N4O7S/c1-12(2)20(25(37)38)31-24(39)13(3)29-23(36)21(14(4)32)30-22(35)18(7-8-19(33)34)28-10-9-15-5-6-16(26)17(27)11-15/h5-6,11-14,18,20-21,28,32H,7-10H2,1-4H3,(H,29,36)(H,30,35)(H,31,39)(H,33,34)(H,37,38)/t13-,14+,18-,20-,21-/m0/s1 MQVRLOSWHOLIPR-QAJIRISXSA-N 50339569 (2S,5S,8S,11S)-11-(2-carboxyethyl)-14-(3,4-dichlorophenyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-5-methyl-7,10-dioxo-4-thioxo-3,6,9,12-tetraazatetradecan-1-oic acid::CHEMBL1688633 Disks large homolog 4 Homo sapiens 8300 ChEMBL 10.1021/jm1013924 10.7270/Q2H13300 21322614 Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Stromgaard, K University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004234&target=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339569&enzyme=Disks+large+homolog+4&column=ki&startPg=0&Increment=50&submit=Search 51350910 125089671 CHEMBL1688633 ZINC66114421 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 1IU0,1IU2,1KEF,1QLC,1RGR,1TP3,1TP5,1TQ3,2KA9,2MES,2MHO,2XKX,3I4W,3WP0,3WP1,4OAJ,5B64,5D13,5GNV,5HDY,5HEB,5HED,5YPO,6QJD,6QJF,6QJG,6QJI,6QJJ,6QJL,6QJN,6SPV,6SPZ,7F7G,7F7I,8AH4,8AH5,8AH6,8AH7,8AH8 Disks large homolog 4 DLG4_HUMAN P78352 B7Z1S1 G5E939 Q92941 Q9UKK8