BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50432445 COC(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCC(=CC1)c1ccccc1)C(=O)NO InChI=1S/C22H27N3O5/c1-30-21(28)25-14-22(9-10-22)13-17(19(26)23-29)18(25)20(27)24-11-7-16(8-12-24)15-5-3-2-4-6-15/h2-7,17-18,29H,8-14H2,1H3,(H,23,26)/t17-,18-/m0/s1 CKZHFOKQZRZCPF-ROUUACIJSA-N 50203527 (6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate::CHEMBL434567::methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 11625778 104082621 CHEMBL434567 ZINC13985960 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517731 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CO)NC1=O InChI=1S/C31H57N11O9/c1-17(2)14-21-28(49)42-23(16-43)30(51)39-19(9-4-6-12-33)26(47)41-22(15-24(44)45)29(50)38-18(8-3-5-11-32)25(46)37-20(27(48)40-21)10-7-13-36-31(34)35/h17-23,43H,3-16,32-33H2,1-2H3,(H,37,46)(H,38,50)(H,39,51)(H,40,48)(H,41,47)(H,42,49)(H,44,45)(H4,34,35,36)/t18-,19-,20-,21-,22-,23+/m0/s1 RMLJWJUSXLSCMR-RCTKEMKKSA-N 50190504 CHEMBL3827850 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 182 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190504&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045154 347830324 CHEMBL3827850 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517732 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC1=O InChI=1S/C31H57N11O9/c1-17(2)14-21-28(49)42-23(16-43)30(51)39-19(9-4-6-12-33)26(47)41-22(15-24(44)45)29(50)38-18(8-3-5-11-32)25(46)37-20(27(48)40-21)10-7-13-36-31(34)35/h17-23,43H,3-16,32-33H2,1-2H3,(H,37,46)(H,38,50)(H,39,51)(H,40,48)(H,41,47)(H,42,49)(H,44,45)(H4,34,35,36)/t18-,19-,20-,21-,22-,23-/m0/s1 RMLJWJUSXLSCMR-LLINQDLYSA-N 50190505 CHEMBL3827893 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 240 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190505&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 25255921 347830325 CHEMBL3827893 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517733 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O InChI=1S/C32H59N11O9/c1-18(2)14-23-30(51)38-19(17-44)15-25(45)39-20(8-3-5-11-33)27(48)43-24(16-26(46)47)31(52)41-21(9-4-6-12-34)28(49)40-22(29(50)42-23)10-7-13-37-32(35)36/h18-24,44H,3-17,33-34H2,1-2H3,(H,38,51)(H,39,45)(H,40,49)(H,41,52)(H,42,50)(H,43,48)(H,46,47)(H4,35,36,37)/t19-,20+,21+,22+,23+,24+/m1/s1 OBRREKIEIBFZAE-CKOZHMEPSA-N 50190506 CHEMBL3828497 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 157 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190506&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044838 347830326 CHEMBL3828497 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517734 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C31H57N11O8/c1-18(2)16-22-26(46)36-15-11-24(43)38-19(8-3-5-12-32)27(47)42-23(17-25(44)45)30(50)40-20(9-4-6-13-33)28(48)39-21(29(49)41-22)10-7-14-37-31(34)35/h18-23H,3-17,32-33H2,1-2H3,(H,36,46)(H,38,43)(H,39,48)(H,40,50)(H,41,49)(H,42,47)(H,44,45)(H4,34,35,37)/t19-,20-,21-,22-,23-/m0/s1 UOGJWVSTBDSXJR-VUBDRERZSA-N 50190507 CHEMBL3827625 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 1645 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190507&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044839 347830327 CHEMBL3827625 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517735 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](NC1=O)C(O)=O InChI=1S/C32H57N11O10/c1-17(2)14-21-29(50)43-23(31(52)53)15-24(44)38-18(8-3-5-11-33)26(47)42-22(16-25(45)46)30(51)40-19(9-4-6-12-34)27(48)39-20(28(49)41-21)10-7-13-37-32(35)36/h17-23H,3-16,33-34H2,1-2H3,(H,38,44)(H,39,48)(H,40,51)(H,41,49)(H,42,47)(H,43,50)(H,45,46)(H,52,53)(H4,35,36,37)/t18-,19-,20-,21-,22-,23-/m0/s1 KMCZEQSSLYSQHT-LLINQDLYSA-N 50190508 CHEMBL3828432 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 420 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190508&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044840 347830328 CHEMBL3828432 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517736 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(=N)N[N+]([O-])=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C31H56N12O10/c1-18(2)16-22-26(47)35-15-11-24(44)37-19(8-3-5-12-32)27(48)41-23(17-25(45)46)30(51)39-20(9-4-6-13-33)28(49)38-21(29(50)40-22)10-7-14-36-31(34)42-43(52)53/h18-23H,3-17,32-33H2,1-2H3,(H,35,47)(H,37,44)(H,38,49)(H,39,51)(H,40,50)(H,41,48)(H,45,46)(H3,34,36,42)/t19-,20-,21-,22-,23-/m0/s1 LXNMDFAQEFKNAT-VUBDRERZSA-N 50190509 CHEMBL3827487 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 2345 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190509&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044845 347830329 CHEMBL3827487 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517737 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C31H56N10O9/c1-18(2)16-22-26(45)35-15-11-24(42)37-19(8-3-5-12-32)27(46)41-23(17-25(43)44)30(49)39-20(9-4-6-13-33)28(47)38-21(29(48)40-22)10-7-14-36-31(34)50/h18-23H,3-17,32-33H2,1-2H3,(H,35,45)(H,37,42)(H,38,47)(H,39,49)(H,40,48)(H,41,46)(H,43,44)(H3,34,36,50)/t19-,20-,21-,22-,23-/m0/s1 QJQNNLICZLLPMB-VUBDRERZSA-N 50190510 CHEMBL3827271 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 890 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190510&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044846 347830330 CHEMBL3827271 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517738 CC(C)(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C32H59N11O8/c1-32(2,3)18-23-26(47)37-16-12-24(44)39-19(9-4-6-13-33)27(48)42-22(17-25(45)46)30(51)41-20(10-5-7-14-34)28(49)40-21(29(50)43-23)11-8-15-38-31(35)36/h19-23H,4-18,33-34H2,1-3H3,(H,37,47)(H,39,44)(H,40,49)(H,41,51)(H,42,48)(H,43,50)(H,45,46)(H4,35,36,38)/t19-,20-,21-,22-,23-/m0/s1 ZRAKGVUCYNKDSS-VUBDRERZSA-N 50190511 CHEMBL3827446 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 256 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190511&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045008 347830331 CHEMBL3827446 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517739 CC(C)CC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C32H59N11O8/c1-19(2)11-12-23-27(47)37-17-13-25(44)39-20(8-3-5-14-33)28(48)43-24(18-26(45)46)31(51)41-21(9-4-6-15-34)29(49)40-22(30(50)42-23)10-7-16-38-32(35)36/h19-24H,3-18,33-34H2,1-2H3,(H,37,47)(H,39,44)(H,40,49)(H,41,51)(H,42,50)(H,43,48)(H,45,46)(H4,35,36,38)/t20-,21-,22-,23-,24-/m0/s1 XIGWBIMPUVXLMW-LSBAASHUSA-N 50190527 CHEMBL3827980 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 220 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045009 347830332 CHEMBL3827980 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517740 CCCC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C31H57N11O8/c1-2-3-9-19-26(46)36-17-13-24(43)38-20(10-4-6-14-32)27(47)42-23(18-25(44)45)30(50)41-21(11-5-7-15-33)28(48)40-22(29(49)39-19)12-8-16-37-31(34)35/h19-23H,2-18,32-33H2,1H3,(H,36,46)(H,38,43)(H,39,49)(H,40,48)(H,41,50)(H,42,47)(H,44,45)(H4,34,35,37)/t19-,20-,21-,22-,23-/m0/s1 SDLGWVQCSQWZHO-VUBDRERZSA-N 50190538 CHEMBL3827647 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 378 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190538&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044673 347830333 CHEMBL3827647 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517741 CCC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C30H55N11O8/c1-2-8-18-25(45)35-16-12-23(42)37-19(9-3-5-13-31)26(46)41-22(17-24(43)44)29(49)40-20(10-4-6-14-32)27(47)39-21(28(48)38-18)11-7-15-36-30(33)34/h18-22H,2-17,31-32H2,1H3,(H,35,45)(H,37,42)(H,38,48)(H,39,47)(H,40,49)(H,41,46)(H,43,44)(H4,33,34,36)/t18-,19-,20-,21-,22-/m0/s1 YSBGHFSYJYINQZ-YFNVTMOMSA-N 50190569 CHEMBL3827027 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 452 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190569&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044674 347830334 CHEMBL3827027 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517742 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C28H51N11O8/c1-15(2)12-18-23(43)33-11-8-21(40)35-16(6-3-4-9-29)24(44)38-19(13-22(41)42)26(46)39-20(14-30)27(47)36-17(25(45)37-18)7-5-10-34-28(31)32/h15-20H,3-14,29-30H2,1-2H3,(H,33,43)(H,35,40)(H,36,47)(H,37,45)(H,38,44)(H,39,46)(H,41,42)(H4,31,32,34)/t16-,17-,18-,19-,20-/m0/s1 ZYIRZDQGNRLPAY-HVTWWXFQSA-N 50190570 CHEMBL3827100 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens >5000 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190570&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044675 347830335 CHEMBL3827100 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517743 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C29H53N11O8/c1-16(2)14-20-24(44)34-13-9-22(41)36-17(6-3-4-10-30)25(45)40-21(15-23(42)43)28(48)38-19(8-11-31)27(47)37-18(26(46)39-20)7-5-12-35-29(32)33/h16-21H,3-15,30-31H2,1-2H3,(H,34,44)(H,36,41)(H,37,47)(H,38,48)(H,39,46)(H,40,45)(H,42,43)(H4,32,33,35)/t17-,18-,19-,20-,21-/m0/s1 FOJOSIWGPNZMGV-SXYSDOLCSA-N 50190571 CHEMBL3828319 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens >5000 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190571&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127044676 347830336 CHEMBL3828319 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517744 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C30H55N11O8/c1-17(2)15-21-25(45)35-14-10-23(42)37-18(7-3-4-11-31)26(46)41-22(16-24(43)44)29(49)39-19(8-5-12-32)27(47)38-20(28(48)40-21)9-6-13-36-30(33)34/h17-22H,3-16,31-32H2,1-2H3,(H,35,45)(H,37,42)(H,38,47)(H,39,49)(H,40,48)(H,41,46)(H,43,44)(H4,33,34,36)/t18-,19-,20-,21-,22-/m0/s1 RHXLRGPYGRLBRC-YFNVTMOMSA-N 50190572 CHEMBL3827131 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens >5000 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190572&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045301 347830337 CHEMBL3827131 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517745 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CCNC1=O InChI=1S/C34H63N11O8/c1-21(2)19-25-29(49)38-17-14-27(46)40-22(11-6-8-15-35)30(50)44-26(20-28(47)48)33(53)42-23(12-7-9-18-45(3,4)5)31(51)41-24(32(52)43-25)13-10-16-39-34(36)37/h21-26H,6-20,35H2,1-5H3,(H10-,36,37,38,39,40,41,42,43,44,46,47,48,49,50,51,52,53)/p+1/t22-,23-,24-,25-,26-/m0/s1 NLVPIQQFDMENHJ-LROMGURASA-O 50190573 CHEMBL3828248 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190573&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045302 347830338 CHEMBL3828248 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517746 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(=N)N[N+]([O-])=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O InChI=1S/C32H58N12O11/c1-18(2)14-23-30(52)37-19(17-45)15-25(46)38-20(8-3-5-11-33)27(49)42-24(16-26(47)48)31(53)40-21(9-4-6-12-34)28(50)39-22(29(51)41-23)10-7-13-36-32(35)43-44(54)55/h18-24,45H,3-17,33-34H2,1-2H3,(H,37,52)(H,38,46)(H,39,50)(H,40,53)(H,41,51)(H,42,49)(H,47,48)(H3,35,36,43)/t19-,20+,21+,22+,23+,24+/m1/s1 ULQPONKJFHXHCL-CKOZHMEPSA-N 50190574 CHEMBL3828603 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 1245 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190574&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045303 347830339 CHEMBL3828603 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517747 CC(C)C[C@@H]1NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O InChI=1S/C32H58N10O10/c1-18(2)14-23-30(50)37-19(17-43)15-25(44)38-20(8-3-5-11-33)27(47)42-24(16-26(45)46)31(51)40-21(9-4-6-12-34)28(48)39-22(29(49)41-23)10-7-13-36-32(35)52/h18-24,43H,3-17,33-34H2,1-2H3,(H,37,50)(H,38,44)(H,39,48)(H,40,51)(H,41,49)(H,42,47)(H,45,46)(H3,35,36,52)/t19-,20+,21+,22+,23+,24+/m1/s1 BHGCMOZGMXWXQJ-CKOZHMEPSA-N 50190575 CHEMBL3827732 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 192 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190575&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045001 347830340 CHEMBL3827732 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517748 CC(C)C[C@@H]1NC(=O)[C@H](CCCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O InChI=1S/C33H61N11O9/c1-19(2)15-24-31(52)39-20(18-45)16-26(46)40-21(9-3-6-12-34)28(49)44-25(17-27(47)48)32(53)42-22(10-4-7-13-35)29(50)41-23(30(51)43-24)11-5-8-14-38-33(36)37/h19-25,45H,3-18,34-35H2,1-2H3,(H,39,52)(H,40,46)(H,41,50)(H,42,53)(H,43,51)(H,44,49)(H,47,48)(H4,36,37,38)/t20-,21+,22+,23+,24+,25+/m1/s1 PWIBEOJPRKLIKI-RFXJPFPRSA-N 50190576 CHEMBL3827091 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 368 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190576&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045002 347830341 CHEMBL3827091 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 50517749 CC(C)CC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C[C@H](CO)NC1=O InChI=1S/C33H61N11O9/c1-19(2)11-12-24-28(49)39-20(18-45)16-26(46)40-21(8-3-5-13-34)29(50)44-25(17-27(47)48)32(53)42-22(9-4-6-14-35)30(51)41-23(31(52)43-24)10-7-15-38-33(36)37/h19-25,45H,3-18,34-35H2,1-2H3,(H,39,49)(H,40,46)(H,41,51)(H,42,53)(H,43,52)(H,44,50)(H,47,48)(H4,36,37,38)/t20-,21+,22+,23+,24+,25+/m1/s1 DBAKVIYGHSOGRY-RFXJPFPRSA-N 50190577 CHEMBL3828456 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 142 ChEMBL 10.1016/j.bmc.2016.06.042 10.7270/Q2ST7RS3 27407033 Yim, V; Noisier, AFM; Hung, KY; Bartsch, JW; Schlomann, U; Brimble, MA University of Auckland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 127045153 347830342 CHEMBL3828456 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508644 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCN InChI=1S/C15H21N5O3/c1-21-11-6-9(5-10-8-19-15(18)20-14(10)17)7-12(22-2)13(11)23-4-3-16/h6-8H,3-5,16H2,1-2H3,(H4,17,18,19,20) STNUPCVMYSYFEG-UHFFFAOYSA-N 50421688 CHEMBL5267938 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 41 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421688&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752277 164150563 CHEMBL171839 ZINC28019914 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508645 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCN1CCOCC1 InChI=1S/C19H27N5O4/c1-25-15-10-13(9-14-12-22-19(21)23-18(14)20)11-16(26-2)17(15)28-8-5-24-3-6-27-7-4-24/h10-12H,3-9H2,1-2H3,(H4,20,21,22,23) NKLUHWRAYBJOQK-UHFFFAOYSA-N 50421689 CHEMBL5283335 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 73 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421689&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752264 164150564 CHEMBL366561 ZINC28013507 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508646 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCN1CCN(C)CC1 InChI=1S/C21H32N6O3/c1-26-6-8-27(9-7-26)5-4-10-30-19-17(28-2)12-15(13-18(19)29-3)11-16-14-24-21(23)25-20(16)22/h12-14H,4-11H2,1-3H3,(H4,22,23,24,25) XGRCXXKTIOPAEE-UHFFFAOYSA-N 50421690 CHEMBL5276957 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 567 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421690&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752271 164150565 CHEMBL173595 ZINC28009842 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508647 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 12 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508675 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCN InChI=1S/C15H21N5O3/c1-21-11-6-9(5-10-8-19-15(18)20-14(10)17)7-12(22-2)13(11)23-4-3-16/h6-8H,3-5,16H2,1-2H3,(H4,17,18,19,20) STNUPCVMYSYFEG-UHFFFAOYSA-N 50421688 CHEMBL5267938 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens >1500 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421688&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752277 164150563 CHEMBL171839 ZINC28019914 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508676 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCN1CCOCC1 InChI=1S/C19H27N5O4/c1-25-15-10-13(9-14-12-22-19(21)23-18(14)20)11-16(26-2)17(15)28-8-5-24-3-6-27-7-4-24/h10-12H,3-9H2,1-2H3,(H4,20,21,22,23) NKLUHWRAYBJOQK-UHFFFAOYSA-N 50421689 CHEMBL5283335 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 350 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421689&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752264 164150564 CHEMBL366561 ZINC28013507 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508677 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCN1CCN(C)CC1 InChI=1S/C21H32N6O3/c1-26-6-8-27(9-7-26)5-4-10-30-19-17(28-2)12-15(13-18(19)29-3)11-16-14-24-21(23)25-20(16)22/h12-14H,4-11H2,1-3H3,(H4,22,23,24,25) XGRCXXKTIOPAEE-UHFFFAOYSA-N 50421690 CHEMBL5276957 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 800 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421690&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 12752271 164150565 CHEMBL173595 ZINC28009842 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39 51508678 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 8 Homo sapiens 120 ChEMBL 10.7270/Q20Z77HJ 35111280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004233&target=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+8&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP 4DD8 Disintegrin and metalloproteinase domain-containing protein 8 ADAM8_HUMAN P78325 B4DVM6 H0YL36 H0YLR0 H0YN39