BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50239446 CN(O)C(=O)CCC(c1ccc(C)cc1)P(O)(O)=O InChI=1S/C12H18NO5P/c1-9-3-5-10(6-4-9)11(19(16,17)18)7-8-12(14)13(2)15/h3-6,11,15H,7-8H2,1-2H3,(H2,16,17,18) YBVPWURHYFIQDS-UHFFFAOYSA-N 50441193 CHEMBL2164256 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1800 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441193&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search IB3 3WQQ 71453383 175453510 CHEMBL2164256 ZINC95552898 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239452 Cc1ccc(cc1)C(CCC(=O)NO)P(O)(O)=O InChI=1S/C11H16NO5P/c1-8-2-4-9(5-3-8)10(18(15,16)17)6-7-11(13)12-14/h2-5,10,14H,6-7H2,1H3,(H,12,13)(H2,15,16,17) SCBADMOVHOXNEN-UHFFFAOYSA-N 50028310 CHEMBL3342258 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 11000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028310&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716370 313065460 CHEMBL3342258 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239460 COc1ccc(cc1)C(CCC(=O)N(C)O)P(O)(O)=O InChI=1S/C12H18NO6P/c1-13(15)12(14)8-7-11(20(16,17)18)9-3-5-10(19-2)6-4-9/h3-6,11,15H,7-8H2,1-2H3,(H2,16,17,18) VLBYPFQOJHBTHH-UHFFFAOYSA-N 50028362 CHEMBL3341763 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028362&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search LSX 3WQR 101882777 103937657 CHEMBL3341763 ZINC00333128 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239469 COc1ccc(cc1)C(CCC(=O)NO)P(O)(O)=O InChI=1S/C11H16NO6P/c1-18-9-4-2-8(3-5-9)10(19(15,16)17)6-7-11(13)12-14/h2-5,10,14H,6-7H2,1H3,(H,12,13)(H2,15,16,17) AEDDLQQMYHWTLI-UHFFFAOYSA-N 50028363 CHEMBL3342259 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 15000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028363&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716371 103937658 CHEMBL3342259 ZINC27849754 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239474 COc1ccc(cc1OC)C(CCC(=O)N(C)O)P(O)(O)=O InChI=1S/C13H20NO7P/c1-14(16)13(15)7-6-12(22(17,18)19)9-4-5-10(20-2)11(8-9)21-3/h4-5,8,12,16H,6-7H2,1-3H3,(H2,17,18,19) MTKVPWZBCNHJJD-UHFFFAOYSA-N 50028364 CHEMBL3342260 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 29000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028364&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716372 313065461 CHEMBL3342260 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239476 COc1ccc(cc1OC)C(CCC(=O)NO)P(O)(O)=O InChI=1S/C12H18NO7P/c1-19-9-4-3-8(7-10(9)20-2)11(21(16,17)18)5-6-12(14)13-15/h3-4,7,11,15H,5-6H2,1-2H3,(H,13,14)(H2,16,17,18) KGPOFMWTMOJKJA-UHFFFAOYSA-N 50028371 CHEMBL3342261 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 163000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028371&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716373 313065462 CHEMBL3342261 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239481 COc1ccc(cc1)C(OCC(=O)N(C)O)P(O)(O)=O InChI=1S/C11H16NO7P/c1-12(14)10(13)7-19-11(20(15,16)17)8-3-5-9(18-2)6-4-8/h3-6,11,14H,7H2,1-2H3,(H2,15,16,17) LUULKKFHGAQKEF-UHFFFAOYSA-N 50028373 CHEMBL3342262 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2800 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028373&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search KBK 3WQS 118716374 313065463 CHEMBL3342262 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239483 COc1ccc(cc1)C(OCC(=O)NO)P(O)(O)=O InChI=1S/C10H14NO7P/c1-17-8-4-2-7(3-5-8)10(19(14,15)16)18-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)(H2,14,15,16) NTZMBAXRHPMPKL-UHFFFAOYSA-N 50028379 CHEMBL3342263 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 352000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028379&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716375 103937671 CHEMBL3342263 ZINC02015756 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239485 CN(O)C(=O)CCCC(c1ccccc1)P(O)(O)=O InChI=1S/C12H18NO5P/c1-13(15)12(14)9-5-8-11(19(16,17)18)10-6-3-2-4-7-10/h2-4,6-7,11,15H,5,8-9H2,1H3,(H2,16,17,18) BJAJYJPPRQEDDK-UHFFFAOYSA-N 50028380 CHEMBL3342264 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 429000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028380&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716376 103937672 CHEMBL3342264 ZINC27517609 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239487 CN(O)C(=O)CCC(NC(=O)c1ccccc1)P(O)(O)=O InChI=1S/C12H17N2O6P/c1-14(17)11(15)8-7-10(21(18,19)20)13-12(16)9-5-3-2-4-6-9/h2-6,10,17H,7-8H2,1H3,(H,13,16)(H2,18,19,20) DIHZMVOBBRRTTG-UHFFFAOYSA-N 50028381 CHEMBL3342265 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 238000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028381&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716377 103937673 CHEMBL3342265 ZINC27521188 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239489 ONC(=O)CCC(NC(=O)c1ccccc1)P(O)(O)=O InChI=1S/C11H15N2O6P/c14-9(13-16)6-7-10(20(17,18)19)12-11(15)8-4-2-1-3-5-8/h1-5,10,16H,6-7H2,(H,12,15)(H,13,14)(H2,17,18,19) JWKYEZZMCLSLEF-UHFFFAOYSA-N 50028382 CHEMBL3342266 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >1000000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028382&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716378 103937674 CHEMBL3342266 ZINC00402909 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239492 Oc1ccccc1NC(=O)CCC(c1ccccc1)P(O)(O)=O InChI=1S/C16H18NO5P/c18-14-9-5-4-8-13(14)17-16(19)11-10-15(23(20,21)22)12-6-2-1-3-7-12/h1-9,15,18H,10-11H2,(H,17,19)(H2,20,21,22) SLXJOFHITNWUEB-UHFFFAOYSA-N 50028383 CHEMBL3342267 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >500000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028383&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716379 103937675 CHEMBL3342267 ZINC27522007 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50239536 OP(O)(=O)CCC(c1cccc2ccccc12)P(O)(O)=O InChI=1S/C13H16O6P2/c14-20(15,16)9-8-13(21(17,18)19)12-7-3-5-10-4-1-2-6-11(10)12/h1-7,13H,8-9H2,(H2,14,15,16)(H2,17,18,19) QOWPWKHZCBRXEB-UHFFFAOYSA-N 50028384 CHEMBL3342268 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >500000 ChEMBL 10.1021/jm500850y 10.7270/Q2KP83RX 25254502 Konzuch, S; Umeda, T; Held, J; Hähn, S; Brücher, K; Lienau, C; Behrendt, CT; Gräwert, T; Bacher, A; Illarionov, B; Fischer, M; Mordmüller, B; Tanaka, N; Kurz, T Heinrich Heine Universit£t http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028384&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118716380 103937676 CHEMBL3342268 ZINC27518973 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50235831 ON(CCCP(O)(O)=O)C(=O)CCCc1ccccc1 InChI=1S/C13H20NO5P/c15-13(14(16)10-5-11-20(17,18)19)9-4-8-12-6-2-1-3-7-12/h1-3,6-7,16H,4-5,8-11H2,(H2,17,18,19) ISSDHTGXAXJCLV-UHFFFAOYSA-N 50026353 CHEMBL3139953 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 17800 ChEMBL 10.1021/jm5010978 10.7270/Q29K4CVJ 25210872 Masini, T; Hirsch, AK University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026353&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71475841 313065237 CHEMBL3139953 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50330013 CN(O)C(=O)CCCP(O)(O)=O InChI=1S/C5H12NO5P/c1-6(8)5(7)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11) OXDGJHZVDJQJCC-UHFFFAOYSA-N 50380000 CHEMBL258981 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 159 ChEMBL 10.1021/jm5014264 10.7270/Q2639RG9 25781377 Chofor, R; Sooriyaarachchi, S; Risseeuw, MD; Bergfors, T; Pouyez, J; Johny, C; Haymond, A; Everaert, A; Dowd, CS; Maes, L; Coenye, T; Alex, A; Couch, RD; Jones, TA; Wouters, J; Mowbray, SL; Van Calenbergh, S Universiteit Gent http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380000&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 9794471 160859083 CHEMBL258981 ZINC29057744 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50330014 CC(CC(=O)N(C)O)CP(O)(O)=O InChI=1S/C6H14NO5P/c1-5(4-13(10,11)12)3-6(8)7(2)9/h5,9H,3-4H2,1-2H3,(H2,10,11,12) ACPXIHKQSXLCRP-UHFFFAOYSA-N 50081647 CHEMBL3422252 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 205 ChEMBL 10.1021/jm5014264 10.7270/Q2639RG9 25781377 Chofor, R; Sooriyaarachchi, S; Risseeuw, MD; Bergfors, T; Pouyez, J; Johny, C; Haymond, A; Everaert, A; Dowd, CS; Maes, L; Coenye, T; Alex, A; Couch, RD; Jones, TA; Wouters, J; Mowbray, SL; Van Calenbergh, S Universiteit Gent http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081647&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118735479 313074388 CHEMBL3422252 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50330015 CN(O)C(=O)CC(CCc1ccccc1)CP(O)([O-])=O InChI=1S/C13H20NO5P/c1-14(16)13(15)9-12(10-20(17,18)19)8-7-11-5-3-2-4-6-11/h2-6,12,16H,7-10H2,1H3,(H2,17,18,19)/p-1 JUYNHKHBYDOVCS-UHFFFAOYSA-M 50081648 CHEMBL3422254 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 31390 ChEMBL 10.1021/jm5014264 10.7270/Q2639RG9 25781377 Chofor, R; Sooriyaarachchi, S; Risseeuw, MD; Bergfors, T; Pouyez, J; Johny, C; Haymond, A; Everaert, A; Dowd, CS; Maes, L; Coenye, T; Alex, A; Couch, RD; Jones, TA; Wouters, J; Mowbray, SL; Van Calenbergh, S Universiteit Gent http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081648&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118988081 313074389 CHEMBL3422254 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50330016 CN(O)C(=O)CC(CCCc1ccccc1)CP(O)([O-])=O InChI=1S/C14H22NO5P/c1-15(17)14(16)10-13(11-21(18,19)20)9-5-8-12-6-3-2-4-7-12/h2-4,6-7,13,17H,5,8-11H2,1H3,(H2,18,19,20)/p-1 YKRNADVNYIPUET-UHFFFAOYSA-M 50081649 CHEMBL3422255 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 843 ChEMBL 10.1021/jm5014264 10.7270/Q2639RG9 25781377 Chofor, R; Sooriyaarachchi, S; Risseeuw, MD; Bergfors, T; Pouyez, J; Johny, C; Haymond, A; Everaert, A; Dowd, CS; Maes, L; Coenye, T; Alex, A; Couch, RD; Jones, TA; Wouters, J; Mowbray, SL; Van Calenbergh, S Universiteit Gent http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081649&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118988082 313074390 CHEMBL3422255 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50330017 [Na+].CN(O)C(=O)CC(CCCCc1ccccc1)CP(O)([O-])=O InChI=1S/C15H24NO5P.Na/c1-16(18)15(17)11-14(12-22(19,20)21)10-6-5-9-13-7-3-2-4-8-13;/h2-4,7-8,14,18H,5-6,9-12H2,1H3,(H2,19,20,21);/q;+1/p-1 HUHJYKXSWOPTLT-UHFFFAOYSA-M 50081650 CHEMBL3422256 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 6670 ChEMBL 10.1021/jm5014264 10.7270/Q2639RG9 25781377 Chofor, R; Sooriyaarachchi, S; Risseeuw, MD; Bergfors, T; Pouyez, J; Johny, C; Haymond, A; Everaert, A; Dowd, CS; Maes, L; Coenye, T; Alex, A; Couch, RD; Jones, TA; Wouters, J; Mowbray, SL; Van Calenbergh, S Universiteit Gent http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081650&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 118735486 103981598 CHEMBL3422256 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647700 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 140 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647701 CC(=O)N(O)CCCP(O)(O)=O InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11) PKMNDDZSIHLLLI-UHFFFAOYSA-N 50181153 3-(N-hydroxyacetamido)propylphosphonic acid::3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL205338::FR-900098::ammonium 3-(N-hydroxyacetamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 130 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181153&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search F98 3AUA,7S04,4A03 162204 104065995 CHEMBL205338 C17942 ZINC28475907 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647702 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C=O InChI=1S/C10H12Cl2NO5P/c11-8-2-1-7(5-9(8)12)10(19(16,17)18)3-4-13(15)6-14/h1-2,5-6,10,15H,3-4H2,(H2,16,17,18) AJGPMMOCRYQLNY-UHFFFAOYSA-N 50181154 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL204106::ammonium 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1200 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181154&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 34F 2Y1D,2Y1F 15949469 104065996 CHEMBL204106 ZINC28572272 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647703 CC(=O)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C11H14Cl2NO5P/c1-7(15)14(16)5-4-11(20(17,18)19)8-2-3-9(12)10(13)6-8/h2-3,6,11,16H,4-5H2,1H3,(H2,17,18,19) ABGCTQYLJZGMBM-UHFFFAOYSA-N 50181148 1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)propylphosphonic acid::CHEMBL204107 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1500 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181148&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search DCV 3RAS 44409705 104065990 CHEMBL204107 ZINC28572274 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647704 OP(O)(=O)C(Nc1nccc2ccccc12)P(O)(O)=O InChI=1S/C10H12N2O6P2/c13-19(14,15)10(20(16,17)18)12-9-8-4-2-1-3-7(8)5-6-11-9/h1-6,10H,(H,11,12)(H2,13,14,15)(H2,16,17,18) JPVMIOWESIQIGB-UHFFFAOYSA-N 50135835 (isoquinolin-1-ylamino)methylenediphosphonic acid::1-[(Bis-phosphono-methyl)-amino]-isoquinolinium::CHEMBL291727::[(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHONIC ACID 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 32700 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135835&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search IMB 1T1R 405731 104026185 CHEMBL291727 ZINC24666638 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647705 On1cc(ccc1=O)-c1ccccc1 InChI=1S/C11H9NO2/c13-11-7-6-10(8-12(11)14)9-4-2-1-3-5-9/h1-8,14H ISVJDQZSLLHGNB-UHFFFAOYSA-N 50335486 1-Hydroxy-5-phenylpyridin-2-one::1-hydroxy-5-phenylpyridin-2(1H)-one::CHEMBL574580 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 21800 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335486&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 44543378 125085588 CHEMBL574580 ZINC45286533 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647706 OP(O)(=O)Cc1ccccn1 InChI=1S/C6H8NO3P/c8-11(9,10)5-6-3-1-2-4-7-6/h1-4H,5H2,(H2,8,9,10) WVWCWWLEFNGDBC-UHFFFAOYSA-N 50335492 (pyridin-2-ylmethyl)phosphonic acid::CHEMBL1615245::Pyridin-2-ylmethylphosphonic acid 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1600 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335492&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search SYC 3ANL 12730177 125085594 CHEMBL1615245 ZINC39275106 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647707 OP(O)(=O)Cc1ccc(cn1)-c1ccccc1 InChI=1S/C12H12NO3P/c14-17(15,16)9-12-7-6-11(8-13-12)10-4-2-1-3-5-10/h1-8H,9H2,(H2,14,15,16) JTYLHYFDHHMHKD-UHFFFAOYSA-N 50335493 5-Phenylpyridin-2-ylmethylphosphonic acid::CHEMBL1615246::[(5-phenylpyridin-2-yl)methyl]phosphonic acid 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 3200 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335493&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search SYD 3ANM 50897581 125085595 CHEMBL1615246 ZINC64744221 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647708 OP(O)(=O)Cc1ccc2ccccc2n1 InChI=1S/C10H10NO3P/c12-15(13,14)7-9-6-5-8-3-1-2-4-10(8)11-9/h1-6H,7H2,(H2,12,13,14) SZCYKKWPKXABPU-UHFFFAOYSA-N 50335494 (quinolin-2-ylmethyl)phosphonic acid::CHEMBL1615247::Quinolin-2-ylmethylphosphonic acid 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 6900 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335494&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search SYE 3ANN 50897582 125085596 CHEMBL1615247 ZINC64744223 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647709 OP(O)(=O)Cc1ccncc1 InChI=1S/C6H8NO3P/c8-11(9,10)5-6-1-3-7-4-2-6/h1-4H,5H2,(H2,8,9,10) FMAPICFMLRVVSP-UHFFFAOYSA-N 50335490 CHEMBL1651840::Pyridin-4-ylmethylphosphonic acid 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 6800 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335490&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 12730175 125085592 CHEMBL1651840 ZINC39275105 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647710 OP(O)(=O)Cc1cc(Br)ccn1 InChI=1S/C6H7BrNO3P/c7-5-1-2-8-6(3-5)4-12(9,10)11/h1-3H,4H2,(H2,9,10,11) CXQPSDJHCUEQEE-UHFFFAOYSA-N 50347577 CHEMBL1801647 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 32700 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347577&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363169 136354263 CHEMBL1801647 ZINC72107162 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647711 OP(O)(=O)Cc1cc(ccn1)-c1ccccc1 InChI=1S/C12H12NO3P/c14-17(15,16)9-12-8-11(6-7-13-12)10-4-2-1-3-5-10/h1-8H,9H2,(H2,14,15,16) AOBQCTXYNAOHOP-UHFFFAOYSA-N 50347578 CHEMBL1801648 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 6900 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347578&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363171 136354264 CHEMBL1801648 ZINC72109633 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647712 OP(O)(=O)Cc1ccc(Br)cn1 InChI=1S/C6H7BrNO3P/c7-5-1-2-6(8-3-5)4-12(9,10)11/h1-3H,4H2,(H2,9,10,11) VQLHJQQMJSAWQS-UHFFFAOYSA-N 50347579 CHEMBL1801650 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 45200 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347579&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363175 136354265 CHEMBL1801650 ZINC72108453 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647713 Oc1ccc(CP(O)(O)=O)nc1 InChI=1S/C6H8NO4P/c8-6-2-1-5(7-3-6)4-12(9,10)11/h1-3,8H,4H2,(H2,9,10,11) KVJQIWKOIARIBN-UHFFFAOYSA-N 50347580 CHEMBL1801651 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 17300 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347580&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363177 136354266 CHEMBL1801651 ZINC72109635 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647714 OP(O)(=O)Cc1ccc(cn1)-c1ccc(F)cc1 InChI=1S/C12H11FNO3P/c13-11-4-1-9(2-5-11)10-3-6-12(14-7-10)8-18(15,16)17/h1-7H,8H2,(H2,15,16,17) PUUKCHGJLPYUGY-UHFFFAOYSA-N 50347581 CHEMBL1801655 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 50700 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347581&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363259 136354267 CHEMBL1801655 ZINC72108551 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647715 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 80 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50647716 OP(O)(=O)Cc1ccncn1 InChI=1S/C5H7N2O3P/c8-11(9,10)3-5-1-2-6-4-7-5/h1-2,4H,3H2,(H2,8,9,10) JFPOJFNCLXTSOD-UHFFFAOYSA-N 50347582 CHEMBL1801642 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 12400 ChEMBL 10.1021/jm200363d 10.7270/Q2NK3FCT 21561155 Deng, L; Diao, J; Chen, P; Pujari, V; Yao, Y; Cheng, G; Crick, DC; Prasad, BV; Song, Y Baylor College of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347582&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 53363091 136354268 CHEMBL1801642 ZINC72107350 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660110 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 80 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660111 CC(=O)N(O)CCCP(O)(O)=O InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11) PKMNDDZSIHLLLI-UHFFFAOYSA-N 50181153 3-(N-hydroxyacetamido)propylphosphonic acid::3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL205338::FR-900098::ammonium 3-(N-hydroxyacetamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 160 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181153&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search F98 3AUA,7S04,4A03 162204 104065995 CHEMBL205338 C17942 ZINC28475907 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660112 CC(=O)N(O)CCCS([O-])(=O)=O InChI=1S/C5H11NO5S/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H,9,10,11)/p-1 KKVMCRJZOUKZKG-UHFFFAOYSA-M 50352792 CHEMBL1823389 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >100000 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352792&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 90814955 136359478 CHEMBL1823389 C15521 ZINC72105999 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660113 CC(=O)N(O)CCc1c(C)onc1C(O)=O InChI=1S/C9H12N2O5/c1-5-7(3-4-11(15)6(2)12)8(9(13)14)10-16-5/h15H,3-4H2,1-2H3,(H,13,14) ZVQXNWVBFVWBGD-UHFFFAOYSA-N 50352793 CHEMBL1823393 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 151000 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352793&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 56680429 136359479 CHEMBL1823393 ZINC72178042 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660114 On1c(CCP(O)(O)=O)cccc1=O InChI=1S/C7H10NO5P/c9-7-3-1-2-6(8(7)10)4-5-14(11,12)13/h1-3,10H,4-5H2,(H2,11,12,13) TYPROGFLNPACFA-UHFFFAOYSA-N 50352794 CHEMBL1823400 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 53000 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352794&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 10130657 136359480 CHEMBL1823400 ZINC34279077 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50660115 Oc1ccc(CCP(O)(O)=O)cc1O InChI=1S/C8H11O5P/c9-7-2-1-6(5-8(7)10)3-4-14(11,12)13/h1-2,5,9-10H,3-4H2,(H2,11,12,13) HLMBWSDLIBEUBX-UHFFFAOYSA-N 50352795 CHEMBL1208368 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 41000 ChEMBL 10.1016/j.bmcl.2011.07.005 10.7270/Q290246H 21824775 Andaloussi, M; Lindh, M; Bjorkelid, C; Suresh, S; Wieckowska, A; Iyer, H; Karlen, A; Larhed, M Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352795&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 44543377 136359481 CHEMBL1208368 ZINC45284861 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50871946 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 80 ChEMBL 10.1074/jbc.M701935200 10.7270/Q28G8MK1 17491006 Henriksson, LM; Unge, T; Carlsson, J; Aqvist, J; Mowbray, SL; Jones, TA Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51088309 CC(=O)N(O)CC=CP(O)([O-])=O InChI=1S/C5H10NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h2,4,8H,3H2,1H3,(H2,9,10,11)/p-1 LJCWFOKLHHHANO-UHFFFAOYSA-M 50445564 CHEMBL3103256 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1070 ChEMBL 10.1016/j.bmcl.2013.11.067 10.7270/Q24Q7WGS 24360562 Jackson, ER; San Jose, G; Brothers, RC; Edelstein, EK; Sheldon, Z; Haymond, A; Johny, C; Boshoff, HI; Couch, RD; Dowd, CS George Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445564&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 91898647 194943460 CHEMBL3103256 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51088310 CC(=O)N(O)CCCP(O)(O)=O InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11) PKMNDDZSIHLLLI-UHFFFAOYSA-N 50181153 3-(N-hydroxyacetamido)propylphosphonic acid::3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL205338::FR-900098::ammonium 3-(N-hydroxyacetamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2390 ChEMBL 10.1016/j.bmcl.2013.11.067 10.7270/Q24Q7WGS 24360562 Jackson, ER; San Jose, G; Brothers, RC; Edelstein, EK; Sheldon, Z; Haymond, A; Johny, C; Boshoff, HI; Couch, RD; Dowd, CS George Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181153&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search F98 3AUA,7S04,4A03 162204 104065995 CHEMBL205338 C17942 ZINC28475907 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51088311 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 440 ChEMBL 10.1016/j.bmcl.2013.11.067 10.7270/Q24Q7WGS 24360562 Jackson, ER; San Jose, G; Brothers, RC; Edelstein, EK; Sheldon, Z; Haymond, A; Johny, C; Boshoff, HI; Couch, RD; Dowd, CS George Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079012 CN(O)C(=O)CS[C@H](c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO5PS/c1-11(13)9(12)7-18-10(17(14,15)16)8-5-3-2-4-6-8/h2-6,10,13H,7H2,1H3,(H2,14,15,16)/t10-/m1/s1 IWQBQVIYTMIQRL-SNVBAGLBSA-N 50441190 CHEMBL2431004 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 83000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441190&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711519 175453507 CHEMBL2431004 ZINC96284889 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079013 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 230 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079014 ONC(=O)CCC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C10H12F2NO5P/c11-7-2-1-6(5-8(7)12)9(19(16,17)18)3-4-10(14)13-15/h1-2,5,9,15H,3-4H2,(H,13,14)(H2,16,17,18) WIEOHPNCBSMHIO-UHFFFAOYSA-N 50441191 CHEMBL1830114 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 3400 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441191&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 54758223 175453508 CHEMBL1830114 ZINC72114778 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079015 ONC(=O)CCC(c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO5P/c12-10(11-13)7-6-9(17(14,15)16)8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,11,12)(H2,14,15,16) AXSYMYWFEVETHK-UHFFFAOYSA-N 50441192 CHEMBL2431005 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 14000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441192&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73353865 175453509 CHEMBL2431005 ZINC96284891 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079016 CN(O)C(=O)CCC(c1ccc(C)cc1)P(O)(O)=O InChI=1S/C12H18NO5P/c1-9-3-5-10(6-4-9)11(19(16,17)18)7-8-12(14)13(2)15/h3-6,11,15H,7-8H2,1-2H3,(H2,16,17,18) YBVPWURHYFIQDS-UHFFFAOYSA-N 50441193 CHEMBL2164256 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1800 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441193&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search IB3 3WQQ 71453383 175453510 CHEMBL2164256 ZINC95552898 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079017 CN(O)C(=O)CCC(c1cccc2ccccc12)P(O)(O)=O InChI=1S/C15H18NO5P/c1-16(18)15(17)10-9-14(22(19,20)21)13-8-4-6-11-5-2-3-7-12(11)13/h2-8,14,18H,9-10H2,1H3,(H2,19,20,21) GVYNITXGUQLLHI-UHFFFAOYSA-N 50441194 CHEMBL1830117 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 13000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441194&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 54758225 175453511 CHEMBL1830117 ZINC72118577 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079018 CN(O)C(=O)CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C11H14Cl2NO5P/c1-14(16)11(15)5-4-10(20(17,18)19)7-2-3-8(12)9(13)6-7/h2-3,6,10,16H,4-5H2,1H3,(H2,17,18,19) UKTXVNQTYFYHAO-UHFFFAOYSA-N 50441195 CHEMBL1830119 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 280 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441195&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 54758227 175453512 CHEMBL1830119 ZINC72118579 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079019 CN(O)C(=O)CCC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C11H14F2NO5P/c1-14(16)11(15)5-4-10(20(17,18)19)7-2-3-8(12)9(13)6-7/h2-3,6,10,16H,4-5H2,1H3,(H2,17,18,19) IZWIBRNXHRUNKD-UHFFFAOYSA-N 50441196 CHEMBL1830118 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 770 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441196&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search C0K 3R0I 54758226 175453513 CHEMBL1830118 ZINC72116318 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079020 CN(O)C(=O)CCC(c1ccccc1)P(O)(O)=O InChI=1S/C11H16NO5P/c1-12(14)11(13)8-7-10(18(15,16)17)9-5-3-2-4-6-9/h2-6,10,14H,7-8H2,1H3,(H2,15,16,17) IVXUMQUJFAYDTH-UHFFFAOYSA-N 50441197 CHEMBL2164255 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441197&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 49850205 175453514 CHEMBL2164255 ZINC95553131 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079021 ONC(=O)COC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C9H10F2NO6P/c10-6-2-1-5(3-7(6)11)9(19(15,16)17)18-4-8(13)12-14/h1-3,9,14H,4H2,(H,12,13)(H2,15,16,17) KPOSWVQLDCXASO-UHFFFAOYSA-N 50441198 CHEMBL2431014 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >500000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441198&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73355391 175453515 CHEMBL2431014 ZINC96284893 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079022 ONC(=O)COC(c1ccccc1)P(O)(O)=O InChI=1S/C9H12NO6P/c11-8(10-12)6-16-9(17(13,14)15)7-4-2-1-3-5-7/h1-5,9,12H,6H2,(H,10,11)(H2,13,14,15) DJJLIOLSYJHFLV-UHFFFAOYSA-N 50441199 CHEMBL2164266 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 466000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441199&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60195028 175453516 CHEMBL2164266 ZINC95556764 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079023 CN(O)C(=O)COC(c1ccc(C)cc1)P(O)(O)=O InChI=1S/C11H16NO6P/c1-8-3-5-9(6-4-8)11(19(15,16)17)18-7-10(13)12(2)14/h3-6,11,14H,7H2,1-2H3,(H2,15,16,17) RRNKZJYPJAPRFT-UHFFFAOYSA-N 50441200 CHEMBL2164264 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 4000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441200&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60195026 175453517 CHEMBL2164264 ZINC95553698 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079024 CN(O)C(=O)COC(c1cccc2ccccc12)P(O)(O)=O InChI=1S/C14H16NO6P/c1-15(17)13(16)9-21-14(22(18,19)20)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,14,17H,9H2,1H3,(H2,18,19,20) RZCGPVVICRPZKJ-UHFFFAOYSA-N 50441201 CHEMBL2164259 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 15000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441201&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60194930 175453518 CHEMBL2164259 ZINC95556441 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079025 CN(O)C(=O)COC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C10H12Cl2NO6P/c1-13(15)9(14)5-19-10(20(16,17)18)6-2-3-7(11)8(12)4-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) BNXJAJGNFMLKQG-UHFFFAOYSA-N 50441202 CHEMBL2164263 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1600 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441202&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60195025 175453519 CHEMBL2164263 ZINC95553957 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079026 CN(O)C(=O)COC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C10H12F2NO6P/c1-13(15)9(14)5-19-10(20(16,17)18)6-2-3-7(11)8(12)4-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) XKRWMTQGABKZDX-UHFFFAOYSA-N 50441203 CHEMBL2164262 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 4600 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441203&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60194933 175453520 CHEMBL2164262 ZINC95555784 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079027 CN(O)C(=O)COC(c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO6P/c1-11(13)9(12)7-17-10(18(14,15)16)8-5-3-2-4-6-8/h2-6,10,13H,7H2,1H3,(H2,14,15,16) JAIZGFIPNLDIAR-UHFFFAOYSA-N 50441204 CHEMBL2164258 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 16000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441204&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 60194929 175453521 CHEMBL2164258 ZINC95554015 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079028 ONC(=O)CSC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C9H10Cl2NO5PS/c10-6-2-1-5(3-7(6)11)9(18(15,16)17)19-4-8(13)12-14/h1-3,9,14H,4H2,(H,12,13)(H2,15,16,17) MMODIMKCMBCKCF-UHFFFAOYSA-N 50441205 CHEMBL2431013 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 720 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441205&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711518 175453522 CHEMBL2431013 ZINC96284895 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079029 ONC(=O)CSC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C9H10F2NO5PS/c10-6-2-1-5(3-7(6)11)9(18(15,16)17)19-4-8(13)12-14/h1-3,9,14H,4H2,(H,12,13)(H2,15,16,17) NRYOYJDZCNIYIA-UHFFFAOYSA-N 50441206 CHEMBL2431012 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1700 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441206&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711299 175453523 CHEMBL2431012 ZINC96284897 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079030 ONC(=O)CSC(c1ccccc1)P(O)(O)=O InChI=1S/C9H12NO5PS/c11-8(10-12)6-17-9(16(13,14)15)7-4-2-1-3-5-7/h1-5,9,12H,6H2,(H,10,11)(H2,13,14,15) IKUWJQAZPLAXHU-UHFFFAOYSA-N 50441207 CHEMBL2431011 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 15000 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441207&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711298 175453524 CHEMBL2431011 ZINC96284899 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079031 CN(O)C(=O)CSC(c1ccc(C)cc1)P(O)(O)=O InChI=1S/C11H16NO5PS/c1-8-3-5-9(6-4-8)11(18(15,16)17)19-7-10(13)12(2)14/h3-6,11,14H,7H2,1-2H3,(H2,15,16,17) YZELONIJQXNWSP-UHFFFAOYSA-N 50441208 CHEMBL2431010 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 110 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441208&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711296 175453525 CHEMBL2431010 ZINC96284901 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079032 CN(O)C(=O)CSC(c1cccc2ccccc12)P(O)(O)=O InChI=1S/C14H16NO5PS/c1-15(17)13(16)9-22-14(21(18,19)20)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,14,17H,9H2,1H3,(H2,18,19,20) RWUHAWVQQUMWLS-UHFFFAOYSA-N 50441209 CHEMBL2431009 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 550 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441209&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711295 175453526 CHEMBL2431009 ZINC96284903 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079033 CN(O)C(=O)CSC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C10H12Cl2NO5PS/c1-13(15)9(14)5-20-10(19(16,17)18)6-2-3-7(11)8(12)4-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) FCHGYCPRLYDAIK-UHFFFAOYSA-N 50441210 CHEMBL2431008 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 9.2 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441210&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711294 175453527 CHEMBL2431008 ZINC96284905 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079034 CN(O)C(=O)CSC(c1ccc(F)c(F)c1)P(O)(O)=O InChI=1S/C10H12F2NO5PS/c1-13(15)9(14)5-20-10(19(16,17)18)6-2-3-7(11)8(12)4-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) OLMCJFHPDFCFTI-UHFFFAOYSA-N 50441211 CHEMBL2431007 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 42 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441211&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 72711293 175453528 CHEMBL2431007 ZINC96284907 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079035 CN(O)C(=O)CS[C@@H](c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO5PS/c1-11(13)9(12)7-18-10(17(14,15)16)8-5-3-2-4-6-8/h2-6,10,13H,7H2,1H3,(H2,14,15,16)/t10-/m0/s1 IWQBQVIYTMIQRL-JTQLQIEISA-N 50441189 CHEMBL2431003 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 280 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441189&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 1UQ 4KP7 71737836 175453506 CHEMBL2431003 ZINC96284888 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51079011 CN(O)C(=O)CS[C@@H](c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO5PS/c1-11(13)9(12)7-18-10(17(14,15)16)8-5-3-2-4-6-8/h2-6,10,13H,7H2,1H3,(H2,14,15,16)/t10-/m0/s1 IWQBQVIYTMIQRL-JTQLQIEISA-N 50441189 CHEMBL2431003 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 120 ChEMBL 10.1021/jm4012559 10.7270/Q2JH3NN8 24032981 Kunfermann, A; Lienau, C; Illarionov, B; Held, J; Gräwert, T; Behrendt, CT; Werner, P; Hähn, S; Eisenreich, W; Riederer, U; Mordmüller, B; Bacher, A; Fischer, M; Groll, M; Kurz, T Lehrstuhl für Biochemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441189&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 1UQ 4KP7 71737836 175453506 CHEMBL2431003 ZINC96284888 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071358 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 80 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071359 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccc(Cn2cncn2)cc1 InChI=1S/C19H19Cl2N4O5P/c20-16-6-5-15(9-17(16)21)18(31(28,29)30)7-8-25(27)19(26)14-3-1-13(2-4-14)10-24-12-22-11-23-24/h1-6,9,11-12,18,27H,7-8,10H2,(H2,28,29,30) MTKONNCMIPCZJN-UHFFFAOYSA-N 50437792 CHEMBL2407194 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 200 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437792&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818542 175450109 CHEMBL2407194 ZINC96273631 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071360 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1cccc(Cn2cncn2)c1 InChI=1S/C19H19Cl2N4O5P/c20-16-5-4-14(9-17(16)21)18(31(28,29)30)6-7-25(27)19(26)15-3-1-2-13(8-15)10-24-12-22-11-23-24/h1-5,8-9,11-12,18,27H,6-7,10H2,(H2,28,29,30) YQKYQGUPTJPWBR-UHFFFAOYSA-N 50437793 CHEMBL2407193 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 170 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437793&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818541 175450110 CHEMBL2407193 ZINC96273633 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071361 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1Cn1cncn1 InChI=1S/C19H19Cl2N4O5P/c20-16-6-5-13(9-17(16)21)18(31(28,29)30)7-8-25(27)19(26)15-4-2-1-3-14(15)10-24-12-22-11-23-24/h1-6,9,11-12,18,27H,7-8,10H2,(H2,28,29,30) CGKYBZFXVQNZBL-UHFFFAOYSA-N 50437794 CHEMBL2407192 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 40 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437794&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM8 3ZI0 71818540 175450111 CHEMBL2407192 ZINC96273635 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071362 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F InChI=1S/C23H20Cl2F3N2O5P/c24-18-9-8-14(12-19(18)25)21(36(33,34)35)10-11-30(32)22(31)17-6-1-2-7-20(17)29-16-5-3-4-15(13-16)23(26,27)28/h1-9,12-13,21,29,32H,10-11H2,(H2,33,34,35) UCTDTGFTTGTERG-UHFFFAOYSA-N 50437795 CHEMBL2407189 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 90 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437795&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM7 3ZHZ 71818537 175450112 CHEMBL2407189 ZINC96273637 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071363 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1OC(F)(F)F InChI=1S/C17H15Cl2F3NO6P/c18-12-6-5-10(9-13(12)19)15(30(26,27)28)7-8-23(25)16(24)11-3-1-2-4-14(11)29-17(20,21)22/h1-6,9,15,25H,7-8H2,(H2,26,27,28) PDZIQZYFJOAVFY-UHFFFAOYSA-N 50437796 CHEMBL2407187 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 90 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437796&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818398 175450113 CHEMBL2407187 ZINC96273639 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071364 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1 InChI=1S/C16H16Cl2NO5P/c17-13-7-6-12(10-14(13)18)15(25(22,23)24)8-9-19(21)16(20)11-4-2-1-3-5-11/h1-7,10,15,21H,8-9H2,(H2,22,23,24) ZQCVCGYWPNFEAH-UHFFFAOYSA-N 50437797 CHEMBL2407184 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 210 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437797&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM6 3ZHY,3ZHX 71818395 175450114 CHEMBL2407184 ZINC96273641 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071365 ON(CCCP(O)(O)=O)C(=O)Cc1ccccc1 InChI=1S/C11H16NO5P/c13-11(9-10-5-2-1-3-6-10)12(14)7-4-8-18(15,16)17/h1-3,5-6,14H,4,7-9H2,(H2,15,16,17) XFWAXDKPSOXCDG-UHFFFAOYSA-N 50437798 CHEMBL2407349 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 320 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437798&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73352128 175450115 CHEMBL2407349 ZINC96273642 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071366 CC(=O)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C11H14Cl2NO5P/c1-7(15)14(16)5-4-11(20(17,18)19)8-2-3-9(12)10(13)6-8/h2-3,6,11,16H,4-5H2,1H3,(H2,17,18,19) ABGCTQYLJZGMBM-UHFFFAOYSA-N 50181148 1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)propylphosphonic acid::CHEMBL204107 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 360 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181148&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search DCV 3RAS 44409705 104065990 CHEMBL204107 ZINC28572274 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071367 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C=O InChI=1S/C10H12Cl2NO5P/c11-8-2-1-7(5-9(8)12)10(19(16,17)18)3-4-13(15)6-14/h1-2,5-6,10,15H,3-4H2,(H2,16,17,18) AJGPMMOCRYQLNY-UHFFFAOYSA-N 50181154 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL204106::ammonium 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 120 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181154&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 34F 2Y1D,2Y1F 15949469 104065996 CHEMBL204106 ZINC28572272 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071368 ON(CCCP(O)(O)=O)C=O InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10) GJXWDTUCERCKIX-UHFFFAOYSA-N 50153713 3-(N-hydroxyformamido)propylphosphonic acid::3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID::CHEMBL203125::[3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid::fosmidomycin 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 40 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153713&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FOM 2JCV,3AU9,2JCX,4AIC,3UPY,4ZQG,4ZQF,2EGH,1ONP,1Q0L,1Q0H,6MH5,3A06,4OOF,4OOE,4ZQH 572 104041488 443725 CHEMBL203125 DB02948 ZINC12502867 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071369 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccc(Cn2cncn2)cc1 InChI=1S/C19H19Cl2N4O5P/c20-16-6-5-15(9-17(16)21)18(31(28,29)30)7-8-25(27)19(26)14-3-1-13(2-4-14)10-24-12-22-11-23-24/h1-6,9,11-12,18,27H,7-8,10H2,(H2,28,29,30) MTKONNCMIPCZJN-UHFFFAOYSA-N 50437792 CHEMBL2407194 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1200 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437792&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818542 175450109 CHEMBL2407194 ZINC96273631 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071370 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1cccc(Cn2cncn2)c1 InChI=1S/C19H19Cl2N4O5P/c20-16-5-4-14(9-17(16)21)18(31(28,29)30)6-7-25(27)19(26)15-3-1-2-13(8-15)10-24-12-22-11-23-24/h1-5,8-9,11-12,18,27H,6-7,10H2,(H2,28,29,30) YQKYQGUPTJPWBR-UHFFFAOYSA-N 50437793 CHEMBL2407193 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 140 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437793&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818541 175450110 CHEMBL2407193 ZINC96273633 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071371 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1Cn1cncn1 InChI=1S/C19H19Cl2N4O5P/c20-16-6-5-13(9-17(16)21)18(31(28,29)30)7-8-25(27)19(26)15-4-2-1-3-14(15)10-24-12-22-11-23-24/h1-6,9,11-12,18,27H,7-8,10H2,(H2,28,29,30) CGKYBZFXVQNZBL-UHFFFAOYSA-N 50437794 CHEMBL2407192 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 13000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437794&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM8 3ZI0 71818540 175450111 CHEMBL2407192 ZINC96273635 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071372 CC(=O)Oc1cccc(c1)C(=O)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C18H18Cl2NO7P/c1-11(22)28-14-4-2-3-13(9-14)18(23)21(24)8-7-17(29(25,26)27)12-5-6-15(19)16(20)10-12/h2-6,9-10,17,24H,7-8H2,1H3,(H2,25,26,27) FUNSHBDZLXZYFW-UHFFFAOYSA-N 50437799 CHEMBL2407191 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >100000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437799&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818539 175450116 CHEMBL2407191 ZINC96273644 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071373 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1-c1ccccc1 InChI=1S/C22H20Cl2NO5P/c23-19-11-10-16(14-20(19)24)21(31(28,29)30)12-13-25(27)22(26)18-9-5-4-8-17(18)15-6-2-1-3-7-15/h1-11,14,21,27H,12-13H2,(H2,28,29,30) SIXABWNYRGQGFY-UHFFFAOYSA-N 50437800 CHEMBL2407190 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 21000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437800&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818538 175450117 CHEMBL2407190 ZINC96273646 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071374 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F InChI=1S/C23H20Cl2F3N2O5P/c24-18-9-8-14(12-19(18)25)21(36(33,34)35)10-11-30(32)22(31)17-6-1-2-7-20(17)29-16-5-3-4-15(13-16)23(26,27)28/h1-9,12-13,21,29,32H,10-11H2,(H2,33,34,35) UCTDTGFTTGTERG-UHFFFAOYSA-N 50437795 CHEMBL2407189 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 19000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437795&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM7 3ZHZ 71818537 175450112 CHEMBL2407189 ZINC96273637 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071375 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1Cc1cccs1 InChI=1S/C21H20Cl2NO5PS/c22-18-8-7-15(13-19(18)23)20(30(27,28)29)9-10-24(26)21(25)17-6-2-1-4-14(17)12-16-5-3-11-31-16/h1-8,11,13,20,26H,9-10,12H2,(H2,27,28,29) RNHFOWGQTCFQEC-UHFFFAOYSA-N 50437801 CHEMBL2407188 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 7000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437801&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818399 175450118 CHEMBL2407188 ZINC96273648 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071376 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1OC(F)(F)F InChI=1S/C17H15Cl2F3NO6P/c18-12-6-5-10(9-13(12)19)15(30(26,27)28)7-8-23(25)16(24)11-3-1-2-4-14(11)29-17(20,21)22/h1-6,9,15,25H,7-8H2,(H2,26,27,28) PDZIQZYFJOAVFY-UHFFFAOYSA-N 50437796 CHEMBL2407187 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 8000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437796&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818398 175450113 CHEMBL2407187 ZINC96273639 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071377 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1C(F)(F)F InChI=1S/C17H15Cl2F3NO5P/c18-13-6-5-10(9-14(13)19)15(29(26,27)28)7-8-23(25)16(24)11-3-1-2-4-12(11)17(20,21)22/h1-6,9,15,25H,7-8H2,(H2,26,27,28) MEDBZDOCGVNSLM-UHFFFAOYSA-N 50437802 CHEMBL2407186 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 9000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437802&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818397 175450119 CHEMBL2407186 ZINC96273650 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071378 Cc1ccccc1C(=O)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C17H18Cl2NO5P/c1-11-4-2-3-5-13(11)17(21)20(22)9-8-16(26(23,24)25)12-6-7-14(18)15(19)10-12/h2-7,10,16,22H,8-9H2,1H3,(H2,23,24,25) RHTCGYHBCJAMDN-UHFFFAOYSA-N 50437803 CHEMBL2407185 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 830 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437803&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 71818396 175450120 CHEMBL2407185 ZINC96273652 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071379 ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C(=O)c1ccccc1 InChI=1S/C16H16Cl2NO5P/c17-13-7-6-12(10-14(13)18)15(25(22,23)24)8-9-19(21)16(20)11-4-2-1-3-5-11/h1-7,10,15,21H,8-9H2,(H2,22,23,24) ZQCVCGYWPNFEAH-UHFFFAOYSA-N 50437797 CHEMBL2407184 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 320 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437797&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search FM6 3ZHY,3ZHX 71818395 175450114 CHEMBL2407184 ZINC96273641 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071380 ON(CCCP(O)(O)=O)C(=O)CNC(=O)CCCOc1ccccc1 InChI=1S/C15H23N2O7P/c18-14(8-4-10-24-13-6-2-1-3-7-13)16-12-15(19)17(20)9-5-11-25(21,22)23/h1-3,6-7,20H,4-5,8-12H2,(H,16,18)(H2,21,22,23) XVWSGEIMEATWFE-UHFFFAOYSA-N 50422649 CHEMBL607353 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >200000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422649&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 46878262 164151524 CHEMBL607353 ZINC13644158 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071381 ON(CCCP(O)(O)=O)C(=O)CNC(=O)C1CC1 InChI=1S/C9H17N2O6P/c12-8(6-10-9(13)7-2-3-7)11(14)4-1-5-18(15,16)17/h7,14H,1-6H2,(H,10,13)(H2,15,16,17) UHCOSYOZVSEXPK-UHFFFAOYSA-N 50422642 CHEMBL607355 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >200000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422642&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 46878264 164151517 CHEMBL607355 ZINC13644161 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071382 ON(CCCP(O)(O)=O)C(=O)Cc1ccccc1 InChI=1S/C11H16NO5P/c13-11(9-10-5-2-1-3-6-10)12(14)7-4-8-18(15,16)17/h1-3,5-6,14H,4,7-9H2,(H2,15,16,17) XFWAXDKPSOXCDG-UHFFFAOYSA-N 50437798 CHEMBL2407349 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 67700 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437798&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73352128 175450115 CHEMBL2407349 ZINC96273642 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071383 ON(CCCP(O)(O)=O)C(=O)c1ccc2ccccc2c1 InChI=1S/C14H16NO5P/c16-14(15(17)8-3-9-21(18,19)20)13-7-6-11-4-1-2-5-12(11)10-13/h1-2,4-7,10,17H,3,8-9H2,(H2,18,19,20) CVMPGCYASBHOSC-UHFFFAOYSA-N 50437804 CHEMBL2407348 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437804&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73350625 175450121 CHEMBL2407348 ZINC96273653 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071384 NC(=O)c1cncc(c1)C(=O)N(O)CCCP(O)(O)=O InChI=1S/C10H14N3O6P/c11-9(14)7-4-8(6-12-5-7)10(15)13(16)2-1-3-20(17,18)19/h4-6,16H,1-3H2,(H2,11,14)(H2,17,18,19) GCOMLAHZHFPXKE-UHFFFAOYSA-N 50437805 CHEMBL2407347 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 3600 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437805&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73352127 175450122 CHEMBL2407347 ZINC96273654 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071385 ON(CCCP(O)(O)=O)C(=O)c1cccnc1 InChI=1S/C9H13N2O5P/c12-9(8-3-1-4-10-7-8)11(13)5-2-6-17(14,15)16/h1,3-4,7,13H,2,5-6H2,(H2,14,15,16) YEEGIHBEADGRCT-UHFFFAOYSA-N 50437806 CHEMBL2407346 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 1600 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437806&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 20337235 175450123 CHEMBL2407346 ZINC60019748 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071386 ON(CCCP(O)(O)=O)C(=O)c1ccccc1 InChI=1S/C10H14NO5P/c12-10(9-5-2-1-3-6-9)11(13)7-4-8-17(14,15)16/h1-3,5-6,13H,4,7-8H2,(H2,14,15,16) IIWMVQGECOWGCK-UHFFFAOYSA-N 50422666 CHEMBL607492 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 2000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422666&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 20185722 164151541 CHEMBL607492 ZINC13644061 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071387 ON(CCCP(O)(O)=O)C(=O)C1CC1 InChI=1S/C7H14NO5P/c9-7(6-2-3-6)8(10)4-1-5-14(11,12)13/h6,10H,1-5H2,(H2,11,12,13) BJJMRCFFXISBLO-UHFFFAOYSA-N 50422660 CHEMBL607357 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 156000 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422660&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 46878265 164151535 CHEMBL607357 ZINC13644167 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071388 ON(CCCP(O)(O)=O)C(=O)c1ccco1 InChI=1S/C8H12NO6P/c10-8(7-3-1-5-15-7)9(11)4-2-6-16(12,13)14/h1,3,5,11H,2,4,6H2,(H2,12,13,14) NPCRUYKFLMALTE-UHFFFAOYSA-N 50437807 CHEMBL2407196 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 48700 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437807&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73355085 175450124 CHEMBL2407196 ZINC96273655 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51071389 CCC(=O)N(O)CCCP(O)(O)=O InChI=1S/C6H14NO5P/c1-2-6(8)7(9)4-3-5-13(10,11)12/h9H,2-5H2,1H3,(H2,10,11,12) WKIFNQPSYJPTSA-UHFFFAOYSA-N 50437808 CHEMBL2407195 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 27200 ChEMBL 10.1021/jm4006498 10.7270/Q2S183W1 23819803 Jansson, AM; Wieckowska, A; Bjorkelid, C; Yahiaoui, S; Sooriyaarachchi, S; Lindh, M; Bergfors, T; Dharavath, S; Desroses, M; Suresh, S; Andaloussi, M; Nikhil, R; Sreevalli, S; Srinivasa, BR; Larhed, M; Jones, TA; Karlen, A; Mowbray, SL Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437808&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 73353579 175450125 CHEMBL2407195 ZINC96273656 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296927 CN(O)C(=O)CS(=O)(=O)C(c1cccc2ccccc12)P(O)(O)=O InChI=1S/C14H16NO7PS/c1-15(17)13(16)9-24(21,22)14(23(18,19)20)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,14,17H,9H2,1H3,(H2,18,19,20) ZVESHGXETCATEP-UHFFFAOYSA-N 50528591 CHEMBL4572338 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 621000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528591&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155564416 440737173 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296929 CN(O)C(=O)CSC(c1cc(F)cc(F)c1)P(O)(O)=O InChI=1S/C10H12F2NO5PS/c1-13(15)9(14)5-20-10(19(16,17)18)6-2-7(11)4-8(12)3-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) IEOBWBKWPIZSFL-UHFFFAOYSA-N 50528593 CHEMBL4590343 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 110 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528593&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155567782 440737175 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296935 COc1cc(OC)cc(c1)C(SCC(=O)N(C)O)P(O)(O)=O InChI=1S/C12H18NO7PS/c1-13(15)11(14)7-22-12(21(16,17)18)8-4-9(19-2)6-10(5-8)20-3/h4-6,12,15H,7H2,1-3H3,(H2,16,17,18) RVEBSJDQWSFUER-UHFFFAOYSA-N 50528597 CHEMBL4592986 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 4400 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528597&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155569185 440737179 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296936 Cc1ccc(cc1)C(SCC(=O)NO)P(O)(O)=O InChI=1S/C10H14NO5PS/c1-7-2-4-8(5-3-7)10(17(14,15)16)18-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)(H2,14,15,16) FBMPGIWVPZIABL-UHFFFAOYSA-N 50528590 CHEMBL4447571 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 8200 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528590&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155518988 440737172 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296937 CSc1ccc(cc1)C(SCC(=O)NO)P(O)(O)=O InChI=1S/C10H14NO5PS2/c1-18-8-4-2-7(3-5-8)10(17(14,15)16)19-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)(H2,14,15,16) HTOYGFWFDNRLAI-UHFFFAOYSA-N 50528598 CHEMBL4474216 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 100 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528598&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155536850 440737180 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296938 ON(CCCP(O)([O-])=O)C=O InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1 ZZPUYRHMTGOTEU-UHFFFAOYSA-M 50028309 Fosmidomycin Sodium 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 230 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028309&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 25245306 313065459 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296939 CN(O)C(=O)CS(=O)(=O)C(c1ccccc1)P(O)(O)=O InChI=1S/C10H14NO7PS/c1-11(13)9(12)7-20(17,18)10(19(14,15)16)8-5-3-2-4-6-8/h2-6,10,13H,7H2,1H3,(H2,14,15,16) RLGGVWUVXOODIC-UHFFFAOYSA-N 50528599 CHEMBL4452553 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 115000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528599&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155522600 440737181 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296940 CN(O)C(=O)CS(=O)(=O)C(c1ccc(Cl)c(Cl)c1)P(O)(O)=O InChI=1S/C10H12Cl2NO7PS/c1-13(15)9(14)5-22(19,20)10(21(16,17)18)6-2-3-7(11)8(12)4-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) HLANOBCZDCGZQO-UHFFFAOYSA-N 50528600 CHEMBL4564404 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 21000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528600&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155559927 440737182 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296941 CN(O)C(=O)CS(=O)(=O)C(c1cc(F)cc(F)c1)P(O)(O)=O InChI=1S/C10H12F2NO7PS/c1-13(15)9(14)5-22(19,20)10(21(16,17)18)6-2-7(11)4-8(12)3-6/h2-4,10,15H,5H2,1H3,(H2,16,17,18) UUQUCESUGTXANS-UHFFFAOYSA-N 50528595 CHEMBL4462089 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 44000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528595&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155528740 440737177 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296942 Cc1ccc(cc1)C(P(O)(O)=O)S(=O)(=O)CC(=O)NO InChI=1S/C10H14NO7PS/c1-7-2-4-8(5-3-7)10(19(14,15)16)20(17,18)6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)(H2,14,15,16) BULHMCQXTNNNEM-UHFFFAOYSA-N 50528596 CHEMBL4578312 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >1000000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528596&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155565062 440737178 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296956 COc1cc(OC)cc(c1)C(P(O)(O)=O)S(=O)(=O)CC(=O)N(C)O InChI=1S/C12H18NO9PS/c1-13(15)11(14)7-24(19,20)12(23(16,17)18)8-4-9(21-2)6-10(5-8)22-3/h4-6,12,15H,7H2,1-3H3,(H2,16,17,18) XELRRDNEFKKXKL-UHFFFAOYSA-N 50528592 CHEMBL4458458 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis >1000000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528592&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155526888 440737174 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296958 ONC(=O)CSC(c1cc(F)cc(F)c1)P(O)(O)=O InChI=1S/C9H10F2NO5PS/c10-6-1-5(2-7(11)3-6)9(18(15,16)17)19-4-8(13)12-14/h1-3,9,14H,4H2,(H,12,13)(H2,15,16,17) CHWZNLZHQNRDMJ-UHFFFAOYSA-N 50528602 CHEMBL4567904 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 320 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528602&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155560634 440737184 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296961 COc1cc(OC)cc(c1)C(SCC(=O)NO)P(O)(O)=O InChI=1S/C11H16NO7PS/c1-18-8-3-7(4-9(5-8)19-2)11(20(15,16)17)21-6-10(13)12-14/h3-5,11,14H,6H2,1-2H3,(H,12,13)(H2,15,16,17) XGGBDHVHUYHYBD-UHFFFAOYSA-N 50528603 CHEMBL4544750 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 44000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528603&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155553015 440737185 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296962 CN(O)C(=O)CS(=O)(=O)C(c1ccc(C)cc1)P(O)(O)=O InChI=1S/C11H16NO7PS/c1-8-3-5-9(6-4-8)11(20(15,16)17)21(18,19)7-10(13)12(2)14/h3-6,11,14H,7H2,1-2H3,(H2,15,16,17) VHPKQQGGKDCFSP-UHFFFAOYSA-N 50528594 CHEMBL4545211 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 143000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528594&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155552963 440737176 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 51296963 COc1cc(OC)cc(c1)C(P(O)(O)=O)S(=O)(=O)CC(=O)NO InChI=1S/C11H16NO9PS/c1-20-8-3-7(4-9(5-8)21-2)11(22(15,16)17)23(18,19)6-10(13)12-14/h3-5,11,14H,6H2,1-2H3,(H,12,13)(H2,15,16,17) SUVNJFICWNSRLX-UHFFFAOYSA-N 50528601 CHEMBL4437978 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 194000 ChEMBL 10.1016/j.ejmech.2019.07.058 10.7270/Q2WW7N4Z 31382119 Lienau, C; Gräwert, T; Alves Avelar, LA; Illarionov, B; Held, J; Knaab, TC; Lungerich, B; van Geelen, L; Meier, D; Geissler, S; Cynis, H; Riederer, U; Buchholz, M; Kalscheuer, R; Bacher, A; Mordmüller, B; Fischer, M; Kurz, T Heinrich Heine University D£sseldorf http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528601&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 155513023 440737183 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50995897 ON(CCCP(O)([O-])=O)C=O InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1 ZZPUYRHMTGOTEU-UHFFFAOYSA-M 50028309 Fosmidomycin Sodium 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 80 ChEMBL 10.7270/Q2417288 33303239 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028309&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search 25245306 313065459 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798 50996114 CC(=O)N(O)CCCP(O)(O)=O InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11) PKMNDDZSIHLLLI-UHFFFAOYSA-N 50181153 3-(N-hydroxyacetamido)propylphosphonic acid::3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL205338::FR-900098::ammonium 3-(N-hydroxyacetamido)propylphosphonate 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mycobacterium tuberculosis 160 ChEMBL 10.7270/Q2417288 33303239 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004227&target=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181153&enzyme=1-deoxy-D-xylulose+5-phosphate+reductoisomerase&column=ki&startPg=0&Increment=50&submit=Search F98 3AUA,7S04,4A03 162204 104065995 CHEMBL205338 C17942 ZINC28475907 1 MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS 2C82,4RCV 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR_MYCTU P9WNS1 L0TDT3 P64012 Q10798