BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51036950 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C151H210N40O35S4/c1-83(2)60-111-140(219)173-99(62-91-44-48-95(194)49-45-91)124(205)146(225)190-57-30-42-109(190)138(217)179-107(128(152)207)79-227-229-150(7,8)126(144(223)181-122(85(5)192)142(221)163-72-115(198)171-105(68-93-70-158-81-167-93)134(213)175-101(64-87-32-20-16-21-33-87)130(209)165-74-118(201)186(12)77-120(203)188(111)14)183-136(215)103(66-89-36-24-18-25-37-89)177-132(211)97(40-28-54-161-148(154)155)169-114(197)53-52-113(196)160-56-59-185(11)76-117(200)170-98(41-29-55-162-149(156)157)133(212)178-104(67-90-38-26-19-27-39-90)137(216)184-127-145(224)182-123(86(6)193)143(222)164-73-116(199)172-106(69-94-71-159-82-168-94)135(214)176-102(65-88-34-22-17-23-35-88)131(210)166-75-119(202)187(13)78-121(204)189(15)112(61-84(3)4)141(220)174-100(63-92-46-50-96(195)51-47-92)125(206)147(226)191-58-31-43-110(191)139(218)180-108(129(153)208)80-228-230-151(127,9)10/h16-27,32-39,44-51,70-71,81-86,97-112,122-123,126-127,192-195H,28-31,40-43,52-69,72-80H2,1-15H3,(H2,152,207)(H2,153,208)(H,158,167)(H,159,168)(H,160,196)(H,163,221)(H,164,222)(H,165,209)(H,166,210)(H,169,197)(H,170,200)(H,171,198)(H,172,199)(H,173,219)(H,174,220)(H,175,213)(H,176,214)(H,177,211)(H,178,212)(H,179,217)(H,180,218)(H,181,223)(H,182,224)(H,183,215)(H,184,216)(H4,154,155,161)(H4,156,157,162)/t85-,86-,97+,98+,99?,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,122+,123+,126-,127-/m1/s1 UAGKVIDRFRKEDI-SMRBASAJSA-N 50314093 CHEMBL1090631 IgG receptor FcRn large subunit p51 Homo sapiens 2.6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314093&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883970 104148454 CHEMBL1090631 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 51036951 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCOCCOCCOCCOCCOCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C156H220N38O39S4/c1-89(2)67-117-145(221)177-105(69-97-43-47-101(197)48-44-97)129(207)151(227)193-55-29-41-115(193)143(219)183-113(133(157)209)85-234-236-155(7,8)131(149(225)185-127(91(5)195)147(223)167-79-121(201)175-111(75-99-77-163-87-171-99)139(215)179-107(71-93-31-19-15-20-32-93)135(211)169-81-123(203)189(11)83-125(205)191(117)13)187-141(217)109(73-95-35-23-17-24-36-95)181-137(213)103(39-27-53-165-153(159)160)173-119(199)51-57-229-59-61-231-63-65-233-66-64-232-62-60-230-58-52-120(200)174-104(40-28-54-166-154(161)162)138(214)182-110(74-96-37-25-18-26-38-96)142(218)188-132-150(226)186-128(92(6)196)148(224)168-80-122(202)176-112(76-100-78-164-88-172-100)140(216)180-108(72-94-33-21-16-22-34-94)136(212)170-82-124(204)190(12)84-126(206)192(14)118(68-90(3)4)146(222)178-106(70-98-45-49-102(198)50-46-98)130(208)152(228)194-56-30-42-116(194)144(220)184-114(134(158)210)86-235-237-156(132,9)10/h15-26,31-38,43-50,77-78,87-92,103-118,127-128,131-132,195-198H,27-30,39-42,51-76,79-86H2,1-14H3,(H2,157,209)(H2,158,210)(H,163,171)(H,164,172)(H,167,223)(H,168,224)(H,169,211)(H,170,212)(H,173,199)(H,174,200)(H,175,201)(H,176,202)(H,177,221)(H,178,222)(H,179,215)(H,180,216)(H,181,213)(H,182,214)(H,183,219)(H,184,220)(H,185,225)(H,186,226)(H,187,217)(H,188,218)(H4,159,160,165)(H4,161,162,166)/t91-,92-,103+,104+,105+,106+,107+,108?,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,127+,128+,131-,132-/m1/s1 RGGXRDUKCFGKPM-WEYJCYFZSA-N 50314096 CHEMBL1090634 IgG receptor FcRn large subunit p51 Homo sapiens 4.8 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314096&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883973 104148457 CHEMBL1090634 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 51036952 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O InChI=1S/C75H104N20O18/c1-42(2)31-58-72(111)88-52(32-47-24-26-49(98)27-25-47)64(103)74(113)95-30-16-23-57(95)71(110)87-50(65(76)104)21-13-14-28-80-59(99)36-56(91-68(107)54(34-46-19-11-8-12-20-46)90-67(106)51(85-44(4)97)22-15-29-81-75(77)78)70(109)92-63(43(3)96)73(112)82-38-60(100)86-55(35-48-37-79-41-84-48)69(108)89-53(33-45-17-9-7-10-18-45)66(105)83-39-61(101)93(5)40-62(102)94(58)6/h7-12,17-20,24-27,37,41-43,50-58,63,96,98H,13-16,21-23,28-36,38-40H2,1-6H3,(H2,76,104)(H,79,84)(H,80,99)(H,82,112)(H,83,105)(H,85,97)(H,86,100)(H,87,110)(H,88,111)(H,89,108)(H,90,106)(H,91,107)(H,92,109)(H4,77,78,81)/t43-,50+,51+,52+,53?,54+,55+,56+,57+,58+,63+/m1/s1 GRUDSXXHTCXYAX-MOVTXUFESA-N 50314083 (3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol-4-yl)methyl)-11-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-23-benzyl-35-(4-hydroxybenzyl)-14-((R)-1-hydroxyethyl)-32-isobutyl-28,31-dimethyl-1,9,12,15,18,21,24,27,30,33,36,37-dodecaoxotetracontahydro-1H-pyrrolo[1,2-z][1,4,7,10,13,16,19,22,26,29,35]undecaazacyclononatriacontine-3-carboxamide::CHEMBL1089951 IgG receptor FcRn large subunit p51 Homo sapiens 1900 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314083&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883960 104148444 CHEMBL1089951 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 51036953 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O InChI=1S/C75H104N20O18/c1-42(2)31-58-72(111)88-52(32-47-24-26-49(98)27-25-47)64(103)74(113)95-30-16-23-57(95)71(110)87-50(65(76)104)21-13-14-28-80-59(99)36-56(91-68(107)54(34-46-19-11-8-12-20-46)90-67(106)51(85-44(4)97)22-15-29-81-75(77)78)70(109)92-63(43(3)96)73(112)82-38-60(100)86-55(35-48-37-79-41-84-48)69(108)89-53(33-45-17-9-7-10-18-45)66(105)83-39-61(101)93(5)40-62(102)94(58)6/h7-12,17-20,24-27,37,41-43,50-58,63,96,98H,13-16,21-23,28-36,38-40H2,1-6H3,(H2,76,104)(H,79,84)(H,80,99)(H,82,112)(H,83,105)(H,85,97)(H,86,100)(H,87,110)(H,88,111)(H,89,108)(H,90,106)(H,91,107)(H,92,109)(H4,77,78,81)/t43-,50+,51+,52+,53?,54+,55+,56+,57+,58+,63+/m1/s1 GRUDSXXHTCXYAX-MOVTXUFESA-N 50314083 (3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol-4-yl)methyl)-11-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-23-benzyl-35-(4-hydroxybenzyl)-14-((R)-1-hydroxyethyl)-32-isobutyl-28,31-dimethyl-1,9,12,15,18,21,24,27,30,33,36,37-dodecaoxotetracontahydro-1H-pyrrolo[1,2-z][1,4,7,10,13,16,19,22,26,29,35]undecaazacyclononatriacontine-3-carboxamide::CHEMBL1089951 IgG receptor FcRn large subunit p51 Homo sapiens 140 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314083&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883960 104148444 CHEMBL1089951 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 51036954 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O InChI=1S/C75H104N20O18/c1-42(2)31-58-72(111)88-52(32-47-24-26-49(98)27-25-47)64(103)74(113)95-30-16-23-57(95)71(110)87-50(65(76)104)21-13-14-28-80-59(99)36-56(91-68(107)54(34-46-19-11-8-12-20-46)90-67(106)51(85-44(4)97)22-15-29-81-75(77)78)70(109)92-63(43(3)96)73(112)82-38-60(100)86-55(35-48-37-79-41-84-48)69(108)89-53(33-45-17-9-7-10-18-45)66(105)83-39-61(101)93(5)40-62(102)94(58)6/h7-12,17-20,24-27,37,41-43,50-58,63,96,98H,13-16,21-23,28-36,38-40H2,1-6H3,(H2,76,104)(H,79,84)(H,80,99)(H,82,112)(H,83,105)(H,85,97)(H,86,100)(H,87,110)(H,88,111)(H,89,108)(H,90,106)(H,91,107)(H,92,109)(H4,77,78,81)/t43-,50+,51+,52+,53?,54+,55+,56+,57+,58+,63+/m1/s1 GRUDSXXHTCXYAX-MOVTXUFESA-N 50314083 (3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol-4-yl)methyl)-11-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-23-benzyl-35-(4-hydroxybenzyl)-14-((R)-1-hydroxyethyl)-32-isobutyl-28,31-dimethyl-1,9,12,15,18,21,24,27,30,33,36,37-dodecaoxotetracontahydro-1H-pyrrolo[1,2-z][1,4,7,10,13,16,19,22,26,29,35]undecaazacyclononatriacontine-3-carboxamide::CHEMBL1089951 IgG receptor FcRn large subunit p51 Homo sapiens 930 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314083&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883960 104148444 CHEMBL1089951 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415529 CC(C)C[C@H](NC(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H98N18O16S2/c1-38(2)27-46(60(95)82-50(30-42-21-23-44(89)24-22-42)66(101)87-26-14-20-52(87)63(98)83-51(36-104)67(102)103)79-54(91)35-86(6)55(92)34-76-59(94)47(28-40-15-9-7-10-16-40)81-61(96)49(31-43-32-73-37-77-43)78-53(90)33-75-64(99)56(39(3)88)84-65(100)57(69(4,5)105)85-62(97)48(29-41-17-11-8-12-18-41)80-58(93)45(70)19-13-25-74-68(71)72/h7-12,15-18,21-24,32,37-39,45-52,56-57,88-89,104-105H,13-14,19-20,25-31,33-36,70H2,1-6H3,(H,73,77)(H,75,99)(H,76,94)(H,78,90)(H,79,91)(H,80,93)(H,81,96)(H,82,95)(H,83,98)(H,84,100)(H,85,97)(H,102,103)(H4,71,72,74)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 GFFSZUTYGTVFIJ-SJGHIIINSA-N 50270831 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL503983 IgG receptor FcRn large subunit p51 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270831&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585722 104115893 CHEMBL503983 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415530 CC(C)C[C@H](N(C)C(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H98N18O16S2/c1-38(2)27-52(63(98)82-49(30-42-21-23-44(89)24-22-42)66(101)87-26-14-20-51(87)62(97)83-50(36-104)67(102)103)86(6)55(92)35-75-53(90)33-76-59(94)46(28-40-15-9-7-10-16-40)81-60(95)48(31-43-32-73-37-78-43)79-54(91)34-77-64(99)56(39(3)88)84-65(100)57(69(4,5)105)85-61(96)47(29-41-17-11-8-12-18-41)80-58(93)45(70)19-13-25-74-68(71)72/h7-12,15-18,21-24,32,37-39,45-52,56-57,88-89,104-105H,13-14,19-20,25-31,33-36,70H2,1-6H3,(H,73,78)(H,75,90)(H,76,94)(H,77,99)(H,79,91)(H,80,93)(H,81,95)(H,82,98)(H,83,97)(H,84,100)(H,85,96)(H,102,103)(H4,71,72,74)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 UQRCNKODMYLDJN-SJGHIIINSA-N 50270830 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504423 IgG receptor FcRn large subunit p51 Homo sapiens 2100 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270830&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585721 104115892 CHEMBL504423 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415531 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N(C)[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-58(81(128)107(6)62(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)77(124)103-57(37-64(88)113)73(120)96-42-68(117)108-30-15-22-61(108)83(130)131)99-66(115)40-93-65(114)39-94-72(119)54(33-47-16-9-7-10-17-47)101-75(122)56(36-50-38-91-44-97-50)98-67(116)41-95-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-76(123)55(34-48-18-11-8-12-19-48)102-74(121)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,126)(H,96,120)(H,98,116)(H,99,115)(H,100,118)(H,101,122)(H,102,121)(H,103,124)(H,104,125)(H,105,127)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 XXXCIDMPGRTGEH-PUBHSFPPSA-N 50270829 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-N,4-dimethylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525782 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270829&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935212 104115891 CHEMBL525782 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415532 CC(C)C[C@H](N(C)C(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-62(79(126)103-58(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)77(124)102-57(37-64(88)113)73(120)96-42-68(117)108-30-15-22-61(108)83(130)131)107(6)67(116)41-93-65(114)39-94-72(119)54(33-47-16-9-7-10-17-47)100-75(122)56(36-50-38-91-44-97-50)98-66(115)40-95-80(127)69(46(3)110)105-81(128)70(85(4,5)133)106-76(123)55(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,118)(H,100,122)(H,101,121)(H,102,124)(H,103,126)(H,104,125)(H,105,128)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 ZEDBZZYGYIFCSI-PUBHSFPPSA-N 50270828 CHEMBL525614 IgG receptor FcRn large subunit p51 Homo sapiens 1600 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270828&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935211 104115890 CHEMBL525614 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415533 CC(C)C[C@H](NC(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(122)103-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)104-60(43-132)78(125)102-58(37-64(88)113)73(120)95-41-68(117)108-30-15-22-62(108)83(130)131)98-66(115)42-107(6)67(116)40-94-72(119)55(33-47-16-9-7-10-17-47)100-76(123)57(36-50-38-91-44-96-50)97-65(114)39-93-80(127)69(46(3)110)105-81(128)70(85(4,5)133)106-77(124)56(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,127)(H,94,119)(H,95,120)(H,97,114)(H,98,115)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,128)(H,106,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 SESMHPMBBHAZKM-PUBHSFPPSA-N 50270827 CHEMBL505899 IgG receptor FcRn large subunit p51 Homo sapiens 900 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270827&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935210 104115889 CHEMBL505899 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415534 CC(C)C[C@H](NC(=O)CNC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(74(121)103-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)78(125)104-60(43-132)77(124)101-57(37-64(88)113)72(119)95-41-68(117)108-30-15-22-62(108)83(130)131)97-65(114)39-93-67(116)42-107(6)81(128)58(34-48-18-11-8-12-19-48)102-75(122)56(36-50-38-91-44-96-50)98-66(115)40-94-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-76(123)55(33-47-16-9-7-10-17-47)100-73(120)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,116)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,118)(H,100,120)(H,101,124)(H,102,122)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 MBHNGANTZSFUGR-PUBHSFPPSA-N 50270826 CHEMBL511030 IgG receptor FcRn large subunit p51 Homo sapiens 27000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270826&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935209 104115888 CHEMBL511030 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415535 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(74(121)103-57(34-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)76(123)102-56(37-64(88)113)72(119)96-42-68(117)108-30-15-22-61(108)83(130)131)98-66(115)40-93-65(114)39-94-77(124)62(35-48-18-11-8-12-19-48)107(6)81(128)58(36-50-38-91-44-97-50)99-67(116)41-95-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-75(122)55(33-47-16-9-7-10-17-47)101-73(120)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,124)(H,95,126)(H,96,119)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,121)(H,104,125)(H,105,127)(H,106,122)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 ABBUWEUHWKXNBZ-PUBHSFPPSA-N 50270825 CHEMBL525587 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270825&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935208 104115887 CHEMBL525587 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415536 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)N(C)C(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H98N18O16S2/c1-38(2)27-46(60(95)82-49(30-42-21-23-44(89)24-22-42)66(101)87-26-14-20-51(87)62(97)83-50(36-104)67(102)103)79-54(91)34-75-53(90)33-76-59(94)47(28-40-15-9-7-10-16-40)81-63(98)52(31-43-32-73-37-78-43)86(6)55(92)35-77-64(99)56(39(3)88)84-65(100)57(69(4,5)105)85-61(96)48(29-41-17-11-8-12-18-41)80-58(93)45(70)19-13-25-74-68(71)72/h7-12,15-18,21-24,32,37-39,45-52,56-57,88-89,104-105H,13-14,19-20,25-31,33-36,70H2,1-6H3,(H,73,78)(H,75,90)(H,76,94)(H,77,99)(H,79,91)(H,80,93)(H,81,98)(H,82,95)(H,83,97)(H,84,100)(H,85,96)(H,102,103)(H4,71,72,74)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 DLKLLAHEYAQCRJ-SJGHIIINSA-N 50270824 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]-N-methylacetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL444490 IgG receptor FcRn large subunit p51 Homo sapiens >250000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270824&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585715 104115886 CHEMBL444490 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415537 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CN(C)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(122)103-59(35-49-23-25-51(111)26-24-49)81(128)109-31-14-21-61(109)79(126)104-60(43-132)78(125)102-58(37-64(88)113)73(120)95-41-68(117)108-30-15-22-62(108)83(130)131)97-66(115)40-93-65(114)39-94-72(119)55(33-47-16-9-7-10-17-47)100-76(123)57(36-50-38-91-44-96-50)98-67(116)42-107(6)82(129)69(46(3)110)105-80(127)70(85(4,5)133)106-77(124)56(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,114)(H,94,119)(H,95,120)(H,97,115)(H,98,116)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,127)(H,106,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 YFMAYOOTAUSJHZ-PUBHSFPPSA-N 50270823 CHEMBL524825 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270823&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935207 104115885 CHEMBL524825 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415538 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O21S2/c1-44(2)30-53(74(119)101-58(33-48-21-23-50(107)24-22-48)80(125)106-29-12-19-61(106)78(123)102-59(41-128)77(122)100-57(35-64(85)109)72(117)93-40-68(113)105-28-13-20-62(105)81(126)127)95-66(111)38-90-65(110)37-92-71(116)54(31-46-14-7-5-8-15-46)98-76(121)56(34-49-36-88-43-94-49)96-67(112)39-91-69(114)45(3)104(4)79(124)60(42-129)103-75(120)55(32-47-16-9-6-10-17-47)99-73(118)52(18-11-27-89-82(86)87)97-70(115)51(83)25-26-63(84)108/h5-10,14-17,21-24,36,43-45,51-62,107,128-129H,11-13,18-20,25-35,37-42,83H2,1-4H3,(H2,84,108)(H2,85,109)(H,88,94)(H,90,110)(H,91,114)(H,92,116)(H,93,117)(H,95,111)(H,96,112)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,123)(H,103,120)(H,126,127)(H4,86,87,89)/t45-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-/m0/s1 ZHNVPKBJRGNGKE-JKGHJVHKSA-N 50270822 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N-methyl-3-sulfanylpropanamido]propanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL502310 IgG receptor FcRn large subunit p51 Homo sapiens 169000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270822&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935206 104115884 CHEMBL502310 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415539 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C68H96N18O16S2/c1-37(2)26-45(59(94)82-49(29-41-20-22-43(88)23-21-41)65(100)86-25-13-19-51(86)62(97)83-50(35-103)66(101)102)78-53(90)33-74-52(89)32-75-58(93)46(27-39-14-8-6-9-15-39)81-60(95)48(30-42-31-72-36-77-42)79-54(91)34-76-63(98)55(38(3)87)84-64(99)56(68(4,5)104)85-61(96)47(28-40-16-10-7-11-17-40)80-57(92)44(69)18-12-24-73-67(70)71/h6-11,14-17,20-23,31,36-38,44-51,55-56,87-88,103-104H,12-13,18-19,24-30,32-35,69H2,1-5H3,(H,72,77)(H,74,89)(H,75,93)(H,76,98)(H,78,90)(H,79,91)(H,80,92)(H,81,95)(H,82,94)(H,83,97)(H,84,99)(H,85,96)(H,101,102)(H4,70,71,73)/t38-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1 JVCZECVFVOVCBB-VSRKBYBNSA-N 50270821 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL446284 IgG receptor FcRn large subunit p51 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270821&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585712 104115883 CHEMBL446284 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415540 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C62H84N14O15S2/c1-34(2)23-42(55(84)72-45(26-38-18-20-40(78)21-19-38)60(89)76-22-12-17-47(76)57(86)73-46(32-92)61(90)91)69-49(80)30-65-48(79)29-66-54(83)43(25-37-15-10-7-11-16-37)71-56(85)44(27-39-28-64-33-68-39)70-50(81)31-67-58(87)51(35(3)77)74-59(88)52(62(4,5)93)75-53(82)41(63)24-36-13-8-6-9-14-36/h6-11,13-16,18-21,28,33-35,41-47,51-52,77-78,92-93H,12,17,22-27,29-32,63H2,1-5H3,(H,64,68)(H,65,79)(H,66,83)(H,67,87)(H,69,80)(H,70,81)(H,71,85)(H,72,84)(H,73,86)(H,74,88)(H,75,82)(H,90,91)/t35-,41+,42+,43+,44+,45+,46+,47+,51+,52-/m1/s1 XXVCSGPXOMEPGM-CGJNYSTESA-N 50270820 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-amino-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL510716 IgG receptor FcRn large subunit p51 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270820&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585711 104115882 CHEMBL510716 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415541 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C85H122N24O22S2/c1-45(2)33-55(76(123)105-60(36-49-22-24-51(111)25-23-49)82(129)109-31-13-20-61(109)79(126)107-70(85(4,5)133)81(128)104-59(38-64(88)113)73(120)96-43-68(117)108-30-14-21-62(108)83(130)131)98-66(115)41-93-65(114)40-94-72(119)56(34-47-15-8-6-9-16-47)102-78(125)58(37-50-39-91-44-97-50)99-67(116)42-95-80(127)69(46(3)110)106-75(122)54(28-32-132)101-77(124)57(35-48-17-10-7-11-18-48)103-74(121)53(19-12-29-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h6-11,15-18,22-25,39,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,26-38,40-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,124)(H,102,125)(H,103,121)(H,104,128)(H,105,123)(H,106,122)(H,107,126)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 MWLRLWROQXIARD-PUBHSFPPSA-N 50270819 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-methyl-3-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504919 IgG receptor FcRn large subunit p51 Homo sapiens 16000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270819&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935205 104115881 CHEMBL504919 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415542 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)33-55(76(123)105-60(36-49-22-24-51(111)25-23-49)82(129)109-31-13-20-61(109)79(126)101-54(28-32-132)75(122)104-59(38-64(88)113)73(120)96-43-68(117)108-30-14-21-62(108)83(130)131)98-66(115)41-93-65(114)40-94-72(119)56(34-47-15-8-6-9-16-47)102-77(124)58(37-50-39-91-44-97-50)99-67(116)42-95-80(127)69(46(3)110)106-81(128)70(85(4,5)133)107-78(125)57(35-48-17-10-7-11-18-48)103-74(121)53(19-12-29-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h6-11,15-18,22-25,39,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,26-38,40-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,126)(H,102,124)(H,103,121)(H,104,122)(H,105,123)(H,106,128)(H,107,125)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 QHXJCRJQOLHTCU-PUBHSFPPSA-N 50270818 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499766 IgG receptor FcRn large subunit p51 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270818&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935204 104115880 CHEMBL499766 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415543 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C86H124N24O22S2/c1-45(2)33-54(75(123)105-59(36-49-24-26-51(112)27-25-49)82(130)110-32-15-22-60(110)78(126)108-69(85(4,5)133)80(128)104-58(38-63(89)114)73(121)97-43-67(118)109-31-16-23-61(109)83(131)132)99-65(116)41-94-64(115)40-95-72(120)55(34-47-17-10-8-11-18-47)102-76(124)57(37-50-39-92-44-98-50)100-66(117)42-96-79(127)68(46(3)111)106-81(129)70(86(6,7)134)107-77(125)56(35-48-19-12-9-13-20-48)103-74(122)53(21-14-30-93-84(90)91)101-71(119)52(87)28-29-62(88)113/h8-13,17-20,24-27,39,44-46,52-61,68-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,120)(H,96,127)(H,97,121)(H,99,116)(H,100,117)(H,101,119)(H,102,124)(H,103,122)(H,104,128)(H,105,123)(H,106,129)(H,107,125)(H,108,126)(H,131,132)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-,70-/m1/s1 RMPKUOUTELFGPQ-ADRXHIGYSA-N 50270817 CHEMBL524659 IgG receptor FcRn large subunit p51 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270817&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935203 104115879 CHEMBL524659 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415544 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)106-69(84(4,5)132)80(127)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-76(123)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-77(124)59(42-131)104-75(122)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,123)(H,101,120)(H,102,127)(H,103,121)(H,104,122)(H,105,124)(H,106,125)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 HFARYWMENZNDHT-JFFCSCEESA-N 50270816 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-methyl-3-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL526861 IgG receptor FcRn large subunit p51 Homo sapiens 18000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270816&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935202 104115878 CHEMBL526861 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415545 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 XMBRKVYGPTUTDQ-JFFCSCEESA-N 50270815 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506647 IgG receptor FcRn large subunit p51 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270815&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935201 104115877 CHEMBL506647 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415546 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59-,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-JQXVWOHMSA-N 50270814 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503890 IgG receptor FcRn large subunit p51 Homo sapiens >500000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270814&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935200 104115876 CHEMBL503890 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415547 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-JIBHXHTASA-N 50270813 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507344 IgG receptor FcRn large subunit p51 Homo sapiens 125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270813&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935199 104115875 CHEMBL507344 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415548 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-UTIIMKRFSA-N 50270812 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525605 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270812&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935198 104115874 CHEMBL525605 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415549 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-54(75(121)103-59(34-48-20-22-50(109)23-21-48)81(127)107-29-11-18-61(107)79(125)104-60(42-131)78(124)102-58(36-64(86)111)72(118)94-41-68(115)106-28-12-19-62(106)82(128)129)96-66(113)39-91-65(112)38-92-71(117)55(32-46-13-6-4-7-14-46)100-77(123)57(35-49-37-89-43-95-49)97-67(114)40-93-80(126)69(45(3)108)105-74(120)53(26-30-130)99-76(122)56(33-47-15-8-5-9-16-47)101-73(119)52(17-10-27-90-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,117)(H,93,126)(H,94,118)(H,96,113)(H,97,114)(H,98,116)(H,99,122)(H,100,123)(H,101,119)(H,102,124)(H,103,121)(H,104,125)(H,105,120)(H,128,129)(H4,87,88,90)/t45-,51+,52+,53-,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 WDRQCHGPEMXUEP-WTYSHWNFSA-N 50270811 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504226 IgG receptor FcRn large subunit p51 Homo sapiens 20000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270811&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935197 104115873 CHEMBL504226 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415550 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-54(75(121)103-59(34-48-20-22-50(109)23-21-48)81(127)107-29-11-18-61(107)79(125)99-53(26-30-130)74(120)102-58(36-64(86)111)72(118)94-41-68(115)106-28-12-19-62(106)82(128)129)96-66(113)39-91-65(112)38-92-71(117)55(32-46-13-6-4-7-14-46)100-77(123)57(35-49-37-89-43-95-49)97-67(114)40-93-80(126)69(45(3)108)105-78(124)60(42-131)104-76(122)56(33-47-15-8-5-9-16-47)101-73(119)52(17-10-27-90-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,117)(H,93,126)(H,94,118)(H,96,113)(H,97,114)(H,98,116)(H,99,125)(H,100,123)(H,101,119)(H,102,120)(H,103,121)(H,104,122)(H,105,124)(H,128,129)(H4,87,88,90)/t45-,51+,52+,53-,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 OOFNNKIMGCCHQM-WTYSHWNFSA-N 50270810 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507004 IgG receptor FcRn large subunit p51 Homo sapiens 21000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270810&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935196 104115872 CHEMBL507004 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415551 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C81H115N23O21S2/c1-43(2)30-53(72(116)99-57(33-48-21-23-50(106)24-22-48)79(123)104-29-12-19-60(104)77(121)101-58(40-126)75(119)93-44(3)68(112)91-39-66(111)103-28-13-20-61(103)80(124)125)94-64(109)37-88-63(108)36-89-70(114)54(31-46-14-7-5-8-15-46)97-74(118)56(34-49-35-86-42-92-49)95-65(110)38-90-78(122)67(45(4)105)102-76(120)59(41-127)100-73(117)55(32-47-16-9-6-10-17-47)98-71(115)52(18-11-27-87-81(84)85)96-69(113)51(82)25-26-62(83)107/h5-10,14-17,21-24,35,42-45,51-61,67,105-106,126-127H,11-13,18-20,25-34,36-41,82H2,1-4H3,(H2,83,107)(H,86,92)(H,88,108)(H,89,114)(H,90,122)(H,91,112)(H,93,119)(H,94,109)(H,95,110)(H,96,113)(H,97,118)(H,98,115)(H,99,116)(H,100,117)(H,101,121)(H,102,120)(H,124,125)(H4,84,85,87)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,67-/m0/s1 PPIIPSJYNJFJCC-RBZKBCOGSA-N 50270809 CHEMBL525060::QRFCTGHFGGLYPCAGP IgG receptor FcRn large subunit p51 Homo sapiens 30000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270809&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935195 104115871 CHEMBL525060 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415552 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C80H114N24O22S2/c1-41(2)27-51(73(119)99-53(30-46-19-21-48(106)22-20-46)72(118)93-42(3)67(113)101-57(38-127)76(122)100-56(32-61(83)108)70(116)91-37-65(112)104-26-12-18-59(104)79(125)126)94-63(110)35-88-62(109)34-89-69(115)52(28-44-13-7-5-8-14-44)97-75(121)55(31-47-33-86-40-92-47)95-64(111)36-90-78(124)66(43(4)105)103-77(123)58(39-128)102-74(120)54(29-45-15-9-6-10-16-45)98-71(117)50(17-11-25-87-80(84)85)96-68(114)49(81)23-24-60(82)107/h5-10,13-16,19-22,33,40-43,49-59,66,105-106,127-128H,11-12,17-18,23-32,34-39,81H2,1-4H3,(H2,82,107)(H2,83,108)(H,86,92)(H,88,109)(H,89,115)(H,90,124)(H,91,116)(H,93,118)(H,94,110)(H,95,111)(H,96,114)(H,97,121)(H,98,117)(H,99,119)(H,100,122)(H,101,113)(H,102,120)(H,103,123)(H,125,126)(H4,84,85,87)/t42-,43+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1 RTSXQTGNHNOUMB-BPXGOGJQSA-N 50270808 CHEMBL524483::QRFCTGHFGGLYACNGP IgG receptor FcRn large subunit p51 Homo sapiens 96000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270808&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935194 104115870 CHEMBL524483 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415553 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O21S2/c1-39(2)26-47(67(112)89-40(3)74(119)100-25-12-19-54(100)72(117)97-52(36-122)70(115)95-51(30-57(79)103)65(110)87-35-61(107)99-24-13-20-55(99)75(120)121)90-59(105)33-84-58(104)32-85-64(109)48(27-42-14-7-5-8-15-42)93-69(114)50(29-44-31-82-38-88-44)91-60(106)34-86-73(118)62(41(4)101)98-71(116)53(37-123)96-68(113)49(28-43-16-9-6-10-17-43)94-66(111)46(18-11-23-83-76(80)81)92-63(108)45(77)21-22-56(78)102/h5-10,14-17,31,38-41,45-55,62,101,122-123H,11-13,18-30,32-37,77H2,1-4H3,(H2,78,102)(H2,79,103)(H,82,88)(H,84,104)(H,85,109)(H,86,118)(H,87,110)(H,89,112)(H,90,105)(H,91,106)(H,92,108)(H,93,114)(H,94,111)(H,95,115)(H,96,113)(H,97,117)(H,98,116)(H,120,121)(H4,80,81,83)/t40-,41+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 AQYIGFNEVYSYMR-CIBQCEIUSA-N 50270807 CHEMBL524301::QRFCTGHFGGLAPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270807&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935193 104115869 CHEMBL524301 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415554 C[C@@H](O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H110N24O22S2/c1-41(66(112)98-54(30-45-19-21-47(105)22-20-45)77(123)103-27-10-17-57(103)75(121)100-55(38-126)73(119)97-53(32-60(82)107)69(115)90-37-64(111)102-26-11-18-58(102)78(124)125)92-62(109)35-87-61(108)34-88-68(114)50(28-43-12-5-3-6-13-43)95-72(118)52(31-46-33-85-40-91-46)93-63(110)36-89-76(122)65(42(2)104)101-74(120)56(39-127)99-71(117)51(29-44-14-7-4-8-15-44)96-70(116)49(16-9-25-86-79(83)84)94-67(113)48(80)23-24-59(81)106/h3-8,12-15,19-22,33,40-42,48-58,65,104-105,126-127H,9-11,16-18,23-32,34-39,80H2,1-2H3,(H2,81,106)(H2,82,107)(H,85,91)(H,87,108)(H,88,114)(H,89,122)(H,90,115)(H,92,109)(H,93,110)(H,94,113)(H,95,118)(H,96,116)(H,97,119)(H,98,112)(H,99,117)(H,100,121)(H,101,120)(H,124,125)(H4,83,84,86)/t41-,42+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,65-/m0/s1 WWJNRJDIESOSSX-PTCAJRAWSA-N 50270806 CHEMBL527054::QRFCTGHFGGAYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 107000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270806&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935192 104115868 CHEMBL527054 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415555 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)98-69(115)44(3)95-65(112)37-91-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)96-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,117)(H,92,126)(H,93,118)(H,95,112)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 NVLFUIQQQXPSCK-ULOXDNNXSA-N 50270805 CHEMBL500525::QRFCTGHFGALYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270805&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935191 104115867 CHEMBL500525 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415556 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)71(117)93-39-67(114)106-28-13-20-62(106)82(128)129)96-65(112)37-91-69(115)44(3)95-73(119)54(31-46-14-7-5-8-15-46)100-76(122)56(34-49-36-89-42-94-49)97-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)99-72(118)52(18-11-27-90-83(87)88)98-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,115)(H,92,126)(H,93,117)(H,95,119)(H,96,112)(H,97,113)(H,98,116)(H,99,118)(H,100,122)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 HROBHVURICMOFT-ULOXDNNXSA-N 50270804 CHEMBL504968::QRFCTGHFAGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270804&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935190 104115866 CHEMBL504968 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415557 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O22S2/c1-38(2)25-47(68(114)95-51(27-42-16-18-44(102)19-17-42)74(120)100-24-9-14-54(100)72(118)97-52(35-123)70(116)94-50(29-57(79)104)65(111)87-34-61(108)99-23-10-15-55(99)75(121)122)90-59(106)32-84-58(105)31-85-63(109)39(3)89-67(113)49(28-43-30-82-37-88-43)91-60(107)33-86-73(119)62(40(4)101)98-71(117)53(36-124)96-69(115)48(26-41-11-6-5-7-12-41)93-66(112)46(13-8-22-83-76(80)81)92-64(110)45(77)20-21-56(78)103/h5-7,11-12,16-19,30,37-40,45-55,62,101-102,123-124H,8-10,13-15,20-29,31-36,77H2,1-4H3,(H2,78,103)(H2,79,104)(H,82,88)(H,84,105)(H,85,109)(H,86,119)(H,87,111)(H,89,113)(H,90,106)(H,91,107)(H,92,110)(H,93,112)(H,94,116)(H,95,114)(H,96,115)(H,97,118)(H,98,117)(H,121,122)(H4,80,81,83)/t39-,40+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 GOKZXJDBZOKFTE-PVLMKORCSA-N 50270803 CHEMBL526348::QRFCTGHAGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270803&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935189 104115865 CHEMBL526348 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415558 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H114N22O22S2/c1-41(2)30-50(71(115)96-54(33-46-21-23-47(103)24-22-46)77(121)101-29-12-19-57(101)75(119)98-55(39-124)73(117)95-53(34-60(82)105)69(113)89-38-64(109)100-28-13-20-58(100)78(122)123)91-63(108)36-86-61(106)35-87-68(112)51(31-44-14-7-5-8-15-44)93-66(110)42(3)90-62(107)37-88-76(120)65(43(4)102)99-74(118)56(40-125)97-72(116)52(32-45-16-9-6-10-17-45)94-70(114)49(18-11-27-85-79(83)84)92-67(111)48(80)25-26-59(81)104/h5-10,14-17,21-24,41-43,48-58,65,102-103,124-125H,11-13,18-20,25-40,80H2,1-4H3,(H2,81,104)(H2,82,105)(H,86,106)(H,87,112)(H,88,120)(H,89,113)(H,90,107)(H,91,108)(H,92,111)(H,93,110)(H,94,114)(H,95,117)(H,96,115)(H,97,116)(H,98,119)(H,99,118)(H,122,123)(H4,83,84,85)/t42-,43+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,65-/m0/s1 KZNISIFFYHJCFV-DCUVTQBESA-N 50270802 CHEMBL501035::QRFCTGAFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270802&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935188 104115864 CHEMBL501035 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415559 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)96-66(113)38-91-65(112)37-92-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)98-69(115)44(3)95-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,112)(H,92,117)(H,93,118)(H,95,126)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 BAXZNYMLTXZPTP-ULOXDNNXSA-N 50270801 CHEMBL524711::QRFCTAHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270801&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935187 104115863 CHEMBL524711 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415560 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C81H114N24O21S2/c1-43(2)29-52(73(118)101-57(32-47-20-22-49(106)23-21-47)79(124)105-28-11-18-60(105)78(123)103-59(41-128)77(122)100-56(34-63(84)108)71(116)92-39-67(112)104-27-12-19-61(104)80(125)126)95-65(110)37-89-64(109)36-91-70(115)53(30-45-13-6-4-7-14-45)98-75(120)55(33-48-35-87-42-93-48)96-66(111)38-90-68(113)44(3)94-76(121)58(40-127)102-74(119)54(31-46-15-8-5-9-16-46)99-72(117)51(17-10-26-88-81(85)86)97-69(114)50(82)24-25-62(83)107/h4-9,13-16,20-23,35,42-44,50-61,106,127-128H,10-12,17-19,24-34,36-41,82H2,1-3H3,(H2,83,107)(H2,84,108)(H,87,93)(H,89,109)(H,90,113)(H,91,115)(H,92,116)(H,94,121)(H,95,110)(H,96,111)(H,97,114)(H,98,120)(H,99,117)(H,100,122)(H,101,118)(H,102,119)(H,103,123)(H,125,126)(H4,85,86,88)/t44-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-/m0/s1 PPQQQQUDHBZTAW-ZUNNVFAGSA-N 50270800 CHEMBL510017::QRFCAGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 30000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270800&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935186 104115862 CHEMBL510017 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415561 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O22S2/c1-38(2)25-47(68(114)95-51(27-42-16-18-44(102)19-17-42)74(120)100-24-9-14-54(100)72(118)97-52(35-123)70(116)94-50(29-57(79)104)66(112)87-34-61(108)99-23-10-15-55(99)75(121)122)90-59(106)32-84-58(105)31-85-65(111)48(26-41-11-6-5-7-12-41)93-69(115)49(28-43-30-82-37-88-43)91-60(107)33-86-73(119)62(40(4)101)98-71(117)53(36-124)96-63(109)39(3)89-67(113)46(13-8-22-83-76(80)81)92-64(110)45(77)20-21-56(78)103/h5-7,11-12,16-19,30,37-40,45-55,62,101-102,123-124H,8-10,13-15,20-29,31-36,77H2,1-4H3,(H2,78,103)(H2,79,104)(H,82,88)(H,84,105)(H,85,111)(H,86,119)(H,87,112)(H,89,113)(H,90,106)(H,91,107)(H,92,110)(H,93,115)(H,94,116)(H,95,114)(H,96,109)(H,97,118)(H,98,117)(H,121,122)(H4,80,81,83)/t39-,40+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 WZFJFPHZIPHUTB-PVLMKORCSA-N 50270799 CHEMBL504145::QRACTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 95000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270799&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935185 104115861 CHEMBL504145 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415562 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H109N21O22S2/c1-41(2)27-50(71(113)95-55(30-46-19-21-48(102)22-20-46)78(120)100-26-11-17-58(100)76(118)97-56(38-123)74(116)94-54(32-61(82)104)70(112)87-37-65(108)99-25-12-18-59(99)79(121)122)90-63(106)35-84-62(105)34-85-69(111)51(28-44-13-7-5-8-14-44)93-73(115)53(31-47-33-83-40-88-47)91-64(107)36-86-77(119)66(43(4)101)98-75(117)57(39-124)96-72(114)52(29-45-15-9-6-10-16-45)92-67(109)42(3)89-68(110)49(80)23-24-60(81)103/h5-10,13-16,19-22,33,40-43,49-59,66,101-102,123-124H,11-12,17-18,23-32,34-39,80H2,1-4H3,(H2,81,103)(H2,82,104)(H,83,88)(H,84,105)(H,85,111)(H,86,119)(H,87,112)(H,89,110)(H,90,106)(H,91,107)(H,92,109)(H,93,115)(H,94,116)(H,95,113)(H,96,114)(H,97,118)(H,98,117)(H,121,122)/t42-,43+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1 JTWFFKOCJDFBHW-BPXGOGJQSA-N 50270798 CHEMBL508486::QAFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 23000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270798&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585689 104115860 CHEMBL508486 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415563 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-53(74(120)102-58(34-48-20-22-50(109)23-21-48)81(127)107-30-11-18-61(107)79(125)104-59(41-130)77(123)101-57(36-64(86)111)72(118)94-40-68(115)106-29-12-19-62(106)82(128)129)97-67(114)39-92-66(113)38-93-71(117)54(32-46-13-6-4-7-14-46)99-76(122)56(35-49-37-89-43-95-49)96-65(112)26-28-90-80(126)69(45(3)108)105-78(124)60(42-131)103-75(121)55(33-47-15-8-5-9-16-47)100-73(119)52(17-10-27-91-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,90,126)(H,92,113)(H,93,117)(H,94,118)(H,96,112)(H,97,114)(H,98,116)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 DAHXZURNAMOGSP-NQDMWGEESA-N 50270837 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{3-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]propanamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508702 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270837&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935218 104115899 CHEMBL508702 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415564 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-43(2)31-54(75(121)103-59(34-49-22-24-51(110)25-23-49)82(128)108-30-13-20-62(108)80(126)105-60(40-131)78(124)102-58(36-65(87)112)72(118)93-39-67(114)107-29-14-21-63(107)83(129)130)99-70(116)45(4)95-69(115)44(3)96-74(120)55(32-47-15-8-6-9-16-47)101-77(123)57(35-50-37-90-42-94-50)97-66(113)38-92-81(127)68(46(5)109)106-79(125)61(41-132)104-76(122)56(33-48-17-10-7-11-18-48)100-73(119)53(19-12-28-91-84(88)89)98-71(117)52(85)26-27-64(86)111/h6-11,15-18,22-25,37,42-46,52-63,68,109-110,131-132H,12-14,19-21,26-36,38-41,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,94)(H,92,127)(H,93,118)(H,95,115)(H,96,120)(H,97,113)(H,98,117)(H,99,116)(H,100,119)(H,101,123)(H,102,124)(H,103,121)(H,104,122)(H,105,126)(H,106,125)(H,129,130)(H4,88,89,91)/t44-,45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,68+/m1/s1 ZBSWPNUTNJHBSC-IILIRIRYSA-N 50270836 CHEMBL499664 IgG receptor FcRn large subunit p51 Homo sapiens 22000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270836&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935217 104115898 CHEMBL499664 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415565 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)98-69(115)44(3)95-65(112)37-91-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)96-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,117)(H,92,126)(H,93,118)(H,95,112)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 NVLFUIQQQXPSCK-QPXGSZJPSA-N 50270835 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2R)-2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}propanamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499402 IgG receptor FcRn large subunit p51 Homo sapiens 12000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270835&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935216 104115897 CHEMBL499402 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415566 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)71(117)93-39-67(114)106-28-13-20-62(106)82(128)129)96-65(112)37-91-69(115)44(3)95-73(119)54(31-46-14-7-5-8-15-46)100-76(122)56(34-49-36-89-42-94-49)97-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)99-72(118)52(18-11-27-90-83(87)88)98-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,115)(H,92,126)(H,93,117)(H,95,119)(H,96,112)(H,97,113)(H,98,116)(H,99,118)(H,100,122)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 HROBHVURICMOFT-QPXGSZJPSA-N 50270834 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]propanamido]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506644 IgG receptor FcRn large subunit p51 Homo sapiens 10000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270834&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935215 104115896 CHEMBL506644 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415567 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)96-66(113)38-91-65(112)37-92-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)98-69(115)44(3)95-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,112)(H,92,117)(H,93,118)(H,95,126)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 BAXZNYMLTXZPTP-QPXGSZJPSA-N 50270833 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]propanamido]-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500533 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270833&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935214 104115895 CHEMBL500533 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415568 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-46(2)33-63(80(127)103-59(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-61(110)79(126)104-60(44-133)78(125)102-58(38-65(89)114)74(121)96-42-68(117)109-31-16-23-62(109)84(131)132)108(7)69(118)43-107(6)67(116)41-95-73(120)55(34-48-17-10-8-11-18-48)100-76(123)57(37-51-39-92-45-97-51)98-66(115)40-94-81(128)70(47(3)111)105-82(129)71(86(4,5)134)106-77(124)56(35-49-19-12-9-13-20-49)101-75(122)54(21-14-30-93-85(90)91)99-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,45-47,53-63,70-71,111-112,133-134H,14-16,21-23,28-38,40-44,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,128)(H,95,120)(H,96,121)(H,98,115)(H,99,119)(H,100,123)(H,101,122)(H,102,125)(H,103,127)(H,104,126)(H,105,129)(H,106,124)(H,131,132)(H4,90,91,93)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 GKJCQNBXNUROBJ-MOZDKIGJSA-N 50270832 CHEMBL525265 IgG receptor FcRn large subunit p51 Homo sapiens 46 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270832&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935213 104115894 CHEMBL525265 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415569 CC(C)C[C@H](NC(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H98N18O16S2/c1-38(2)27-46(60(95)82-50(30-42-21-23-44(89)24-22-42)66(101)87-26-14-20-52(87)63(98)83-51(36-104)67(102)103)79-54(91)35-86(6)55(92)34-76-59(94)47(28-40-15-9-7-10-16-40)81-61(96)49(31-43-32-73-37-77-43)78-53(90)33-75-64(99)56(39(3)88)84-65(100)57(69(4,5)105)85-62(97)48(29-41-17-11-8-12-18-41)80-58(93)45(70)19-13-25-74-68(71)72/h7-12,15-18,21-24,32,37-39,45-52,56-57,88-89,104-105H,13-14,19-20,25-31,33-36,70H2,1-6H3,(H,73,77)(H,75,99)(H,76,94)(H,78,90)(H,79,91)(H,80,93)(H,81,96)(H,82,95)(H,83,98)(H,84,100)(H,85,97)(H,102,103)(H4,71,72,74)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 GFFSZUTYGTVFIJ-SJGHIIINSA-N 50270831 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL503983 IgG receptor FcRn large subunit p51 Homo sapiens 58 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270831&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585722 104115893 CHEMBL503983 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415570 CC(C)C[C@H](N(C)C(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H98N18O16S2/c1-38(2)27-52(63(98)82-49(30-42-21-23-44(89)24-22-42)66(101)87-26-14-20-51(87)62(97)83-50(36-104)67(102)103)86(6)55(92)35-75-53(90)33-76-59(94)46(28-40-15-9-7-10-16-40)81-60(95)48(31-43-32-73-37-78-43)79-54(91)34-77-64(99)56(39(3)88)84-65(100)57(69(4,5)105)85-61(96)47(29-41-17-11-8-12-18-41)80-58(93)45(70)19-13-25-74-68(71)72/h7-12,15-18,21-24,32,37-39,45-52,56-57,88-89,104-105H,13-14,19-20,25-31,33-36,70H2,1-6H3,(H,73,78)(H,75,90)(H,76,94)(H,77,99)(H,79,91)(H,80,93)(H,81,95)(H,82,98)(H,83,97)(H,84,100)(H,85,96)(H,102,103)(H4,71,72,74)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 UQRCNKODMYLDJN-SJGHIIINSA-N 50270830 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504423 IgG receptor FcRn large subunit p51 Homo sapiens 59 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270830&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585721 104115892 CHEMBL504423 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415571 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N(C)[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-58(81(128)107(6)62(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)77(124)103-57(37-64(88)113)73(120)96-42-68(117)108-30-15-22-61(108)83(130)131)99-66(115)40-93-65(114)39-94-72(119)54(33-47-16-9-7-10-17-47)101-75(122)56(36-50-38-91-44-97-50)98-67(116)41-95-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-76(123)55(34-48-18-11-8-12-19-48)102-74(121)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,126)(H,96,120)(H,98,116)(H,99,115)(H,100,118)(H,101,122)(H,102,121)(H,103,124)(H,104,125)(H,105,127)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 XXXCIDMPGRTGEH-PUBHSFPPSA-N 50270829 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-N,4-dimethylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525782 IgG receptor FcRn large subunit p51 Homo sapiens 92000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270829&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935212 104115891 CHEMBL525782 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415572 CC(C)C[C@H](N(C)C(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-62(79(126)103-58(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)77(124)102-57(37-64(88)113)73(120)96-42-68(117)108-30-15-22-61(108)83(130)131)107(6)67(116)41-93-65(114)39-94-72(119)54(33-47-16-9-7-10-17-47)100-75(122)56(36-50-38-91-44-97-50)98-66(115)40-95-80(127)69(46(3)110)105-81(128)70(85(4,5)133)106-76(123)55(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,118)(H,100,122)(H,101,121)(H,102,124)(H,103,126)(H,104,125)(H,105,128)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 ZEDBZZYGYIFCSI-PUBHSFPPSA-N 50270828 CHEMBL525614 IgG receptor FcRn large subunit p51 Homo sapiens 86 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270828&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935211 104115890 CHEMBL525614 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415573 CC(C)C[C@H](NC(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(122)103-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)104-60(43-132)78(125)102-58(37-64(88)113)73(120)95-41-68(117)108-30-15-22-62(108)83(130)131)98-66(115)42-107(6)67(116)40-94-72(119)55(33-47-16-9-7-10-17-47)100-76(123)57(36-50-38-91-44-96-50)97-65(114)39-93-80(127)69(46(3)110)105-81(128)70(85(4,5)133)106-77(124)56(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,127)(H,94,119)(H,95,120)(H,97,114)(H,98,115)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,128)(H,106,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 SESMHPMBBHAZKM-PUBHSFPPSA-N 50270827 CHEMBL505899 IgG receptor FcRn large subunit p51 Homo sapiens 110 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270827&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935210 104115889 CHEMBL505899 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415574 CC(C)C[C@H](NC(=O)CNC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(74(121)103-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)78(125)104-60(43-132)77(124)101-57(37-64(88)113)72(119)95-41-68(117)108-30-15-22-62(108)83(130)131)97-65(114)39-93-67(116)42-107(6)81(128)58(34-48-18-11-8-12-19-48)102-75(122)56(36-50-38-91-44-96-50)98-66(115)40-94-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-76(123)55(33-47-16-9-7-10-17-47)100-73(120)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,116)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,118)(H,100,120)(H,101,124)(H,102,122)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 MBHNGANTZSFUGR-PUBHSFPPSA-N 50270826 CHEMBL511030 IgG receptor FcRn large subunit p51 Homo sapiens 2000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270826&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935209 104115888 CHEMBL511030 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415575 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(74(121)103-57(34-49-23-25-51(111)26-24-49)82(129)109-31-14-21-60(109)78(125)104-59(43-132)76(123)102-56(37-64(88)113)72(119)96-42-68(117)108-30-15-22-61(108)83(130)131)98-66(115)40-93-65(114)39-94-77(124)62(35-48-18-11-8-12-19-48)107(6)81(128)58(36-50-38-91-44-97-50)99-67(116)41-95-79(126)69(46(3)110)105-80(127)70(85(4,5)133)106-75(122)55(33-47-16-9-7-10-17-47)101-73(120)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,124)(H,95,126)(H,96,119)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,121)(H,104,125)(H,105,127)(H,106,122)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 ABBUWEUHWKXNBZ-PUBHSFPPSA-N 50270825 CHEMBL525587 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270825&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935208 104115887 CHEMBL525587 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415576 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CN(C)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(122)103-59(35-49-23-25-51(111)26-24-49)81(128)109-31-14-21-61(109)79(126)104-60(43-132)78(125)102-58(37-64(88)113)73(120)95-41-68(117)108-30-15-22-62(108)83(130)131)97-66(115)40-93-65(114)39-94-72(119)55(33-47-16-9-7-10-17-47)100-76(123)57(36-50-38-91-44-96-50)98-67(116)42-107(6)82(129)69(46(3)110)105-80(127)70(85(4,5)133)106-77(124)56(34-48-18-11-8-12-19-48)101-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,44-46,52-62,69-70,110-111,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,114)(H,94,119)(H,95,120)(H,97,115)(H,98,116)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,127)(H,106,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 YFMAYOOTAUSJHZ-PUBHSFPPSA-N 50270823 CHEMBL524825 IgG receptor FcRn large subunit p51 Homo sapiens 88000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270823&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935207 104115885 CHEMBL524825 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415577 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O21S2/c1-44(2)30-53(74(119)101-58(33-48-21-23-50(107)24-22-48)80(125)106-29-12-19-61(106)78(123)102-59(41-128)77(122)100-57(35-64(85)109)72(117)93-40-68(113)105-28-13-20-62(105)81(126)127)95-66(111)38-90-65(110)37-92-71(116)54(31-46-14-7-5-8-15-46)98-76(121)56(34-49-36-88-43-94-49)96-67(112)39-91-69(114)45(3)104(4)79(124)60(42-129)103-75(120)55(32-47-16-9-6-10-17-47)99-73(118)52(18-11-27-89-82(86)87)97-70(115)51(83)25-26-63(84)108/h5-10,14-17,21-24,36,43-45,51-62,107,128-129H,11-13,18-20,25-35,37-42,83H2,1-4H3,(H2,84,108)(H2,85,109)(H,88,94)(H,90,110)(H,91,114)(H,92,116)(H,93,117)(H,95,111)(H,96,112)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,123)(H,103,120)(H,126,127)(H4,86,87,89)/t45-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-/m0/s1 ZHNVPKBJRGNGKE-JKGHJVHKSA-N 50270822 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N-methyl-3-sulfanylpropanamido]propanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL502310 IgG receptor FcRn large subunit p51 Homo sapiens 18000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270822&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935206 104115884 CHEMBL502310 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415578 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C68H96N18O16S2/c1-37(2)26-45(59(94)82-49(29-41-20-22-43(88)23-21-41)65(100)86-25-13-19-51(86)62(97)83-50(35-103)66(101)102)78-53(90)33-74-52(89)32-75-58(93)46(27-39-14-8-6-9-15-39)81-60(95)48(30-42-31-72-36-77-42)79-54(91)34-76-63(98)55(38(3)87)84-64(99)56(68(4,5)104)85-61(96)47(28-40-16-10-7-11-17-40)80-57(92)44(69)18-12-24-73-67(70)71/h6-11,14-17,20-23,31,36-38,44-51,55-56,87-88,103-104H,12-13,18-19,24-30,32-35,69H2,1-5H3,(H,72,77)(H,74,89)(H,75,93)(H,76,98)(H,78,90)(H,79,91)(H,80,92)(H,81,95)(H,82,94)(H,83,97)(H,84,99)(H,85,96)(H,101,102)(H4,70,71,73)/t38-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1 JVCZECVFVOVCBB-VSRKBYBNSA-N 50270821 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL446284 IgG receptor FcRn large subunit p51 Homo sapiens 170 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270821&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585712 104115883 CHEMBL446284 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415579 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C62H84N14O15S2/c1-34(2)23-42(55(84)72-45(26-38-18-20-40(78)21-19-38)60(89)76-22-12-17-47(76)57(86)73-46(32-92)61(90)91)69-49(80)30-65-48(79)29-66-54(83)43(25-37-15-10-7-11-16-37)71-56(85)44(27-39-28-64-33-68-39)70-50(81)31-67-58(87)51(35(3)77)74-59(88)52(62(4,5)93)75-53(82)41(63)24-36-13-8-6-9-14-36/h6-11,13-16,18-21,28,33-35,41-47,51-52,77-78,92-93H,12,17,22-27,29-32,63H2,1-5H3,(H,64,68)(H,65,79)(H,66,83)(H,67,87)(H,69,80)(H,70,81)(H,71,85)(H,72,84)(H,73,86)(H,74,88)(H,75,82)(H,90,91)/t35-,41+,42+,43+,44+,45+,46+,47+,51+,52-/m1/s1 XXVCSGPXOMEPGM-CGJNYSTESA-N 50270820 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-amino-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL510716 IgG receptor FcRn large subunit p51 Homo sapiens 310 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270820&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585711 104115882 CHEMBL510716 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415580 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C85H122N24O22S2/c1-45(2)33-55(76(123)105-60(36-49-22-24-51(111)25-23-49)82(129)109-31-13-20-61(109)79(126)107-70(85(4,5)133)81(128)104-59(38-64(88)113)73(120)96-43-68(117)108-30-14-21-62(108)83(130)131)98-66(115)41-93-65(114)40-94-72(119)56(34-47-15-8-6-9-16-47)102-78(125)58(37-50-39-91-44-97-50)99-67(116)42-95-80(127)69(46(3)110)106-75(122)54(28-32-132)101-77(124)57(35-48-17-10-7-11-18-48)103-74(121)53(19-12-29-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h6-11,15-18,22-25,39,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,26-38,40-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,124)(H,102,125)(H,103,121)(H,104,128)(H,105,123)(H,106,122)(H,107,126)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 MWLRLWROQXIARD-PUBHSFPPSA-N 50270819 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-methyl-3-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504919 IgG receptor FcRn large subunit p51 Homo sapiens 2100 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270819&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935205 104115881 CHEMBL504919 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415581 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)33-55(76(123)105-60(36-49-22-24-51(111)25-23-49)82(129)109-31-13-20-61(109)79(126)101-54(28-32-132)75(122)104-59(38-64(88)113)73(120)96-43-68(117)108-30-14-21-62(108)83(130)131)98-66(115)41-93-65(114)40-94-72(119)56(34-47-15-8-6-9-16-47)102-77(124)58(37-50-39-91-44-97-50)99-67(116)42-95-80(127)69(46(3)110)106-81(128)70(85(4,5)133)107-78(125)57(35-48-17-10-7-11-18-48)103-74(121)53(19-12-29-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h6-11,15-18,22-25,39,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,26-38,40-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,126)(H,102,124)(H,103,121)(H,104,122)(H,105,123)(H,106,128)(H,107,125)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 QHXJCRJQOLHTCU-PUBHSFPPSA-N 50270818 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499766 IgG receptor FcRn large subunit p51 Homo sapiens 310 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270818&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935204 104115880 CHEMBL499766 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415582 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C86H124N24O22S2/c1-45(2)33-54(75(123)105-59(36-49-24-26-51(112)27-25-49)82(130)110-32-15-22-60(110)78(126)108-69(85(4,5)133)80(128)104-58(38-63(89)114)73(121)97-43-67(118)109-31-16-23-61(109)83(131)132)99-65(116)41-94-64(115)40-95-72(120)55(34-47-17-10-8-11-18-47)102-76(124)57(37-50-39-92-44-98-50)100-66(117)42-96-79(127)68(46(3)111)106-81(129)70(86(6,7)134)107-77(125)56(35-48-19-12-9-13-20-48)103-74(122)53(21-14-30-93-84(90)91)101-71(119)52(87)28-29-62(88)113/h8-13,17-20,24-27,39,44-46,52-61,68-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,120)(H,96,127)(H,97,121)(H,99,116)(H,100,117)(H,101,119)(H,102,124)(H,103,122)(H,104,128)(H,105,123)(H,106,129)(H,107,125)(H,108,126)(H,131,132)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-,70-/m1/s1 RMPKUOUTELFGPQ-ADRXHIGYSA-N 50270817 CHEMBL524659 IgG receptor FcRn large subunit p51 Homo sapiens 370 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270817&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935203 104115879 CHEMBL524659 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415583 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)C(C)(C)S InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)106-69(84(4,5)132)80(127)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-76(123)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-77(124)59(42-131)104-75(122)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,123)(H,101,120)(H,102,127)(H,103,121)(H,104,122)(H,105,124)(H,106,125)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 HFARYWMENZNDHT-JFFCSCEESA-N 50270816 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-methyl-3-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL526861 IgG receptor FcRn large subunit p51 Homo sapiens 2700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270816&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935202 104115878 CHEMBL526861 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415584 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 XMBRKVYGPTUTDQ-JFFCSCEESA-N 50270815 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506647 IgG receptor FcRn large subunit p51 Homo sapiens 250 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270815&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935201 104115877 CHEMBL506647 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415585 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59-,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-JQXVWOHMSA-N 50270814 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503890 IgG receptor FcRn large subunit p51 Homo sapiens 200000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270814&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935200 104115876 CHEMBL503890 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415586 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-JIBHXHTASA-N 50270813 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507344 IgG receptor FcRn large subunit p51 Homo sapiens 31000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270813&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935199 104115875 CHEMBL507344 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415587 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-UTIIMKRFSA-N 50270812 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525605 IgG receptor FcRn large subunit p51 Homo sapiens 150000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270812&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935198 104115874 CHEMBL525605 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415588 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-54(75(121)103-59(34-48-20-22-50(109)23-21-48)81(127)107-29-11-18-61(107)79(125)104-60(42-131)78(124)102-58(36-64(86)111)72(118)94-41-68(115)106-28-12-19-62(106)82(128)129)96-66(113)39-91-65(112)38-92-71(117)55(32-46-13-6-4-7-14-46)100-77(123)57(35-49-37-89-43-95-49)97-67(114)40-93-80(126)69(45(3)108)105-74(120)53(26-30-130)99-76(122)56(33-47-15-8-5-9-16-47)101-73(119)52(17-10-27-90-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,117)(H,93,126)(H,94,118)(H,96,113)(H,97,114)(H,98,116)(H,99,122)(H,100,123)(H,101,119)(H,102,124)(H,103,121)(H,104,125)(H,105,120)(H,128,129)(H4,87,88,90)/t45-,51+,52+,53-,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 WDRQCHGPEMXUEP-WTYSHWNFSA-N 50270811 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504226 IgG receptor FcRn large subunit p51 Homo sapiens 3800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270811&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935197 104115873 CHEMBL504226 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415589 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-54(75(121)103-59(34-48-20-22-50(109)23-21-48)81(127)107-29-11-18-61(107)79(125)99-53(26-30-130)74(120)102-58(36-64(86)111)72(118)94-41-68(115)106-28-12-19-62(106)82(128)129)96-66(113)39-91-65(112)38-92-71(117)55(32-46-13-6-4-7-14-46)100-77(123)57(35-49-37-89-43-95-49)97-67(114)40-93-80(126)69(45(3)108)105-78(124)60(42-131)104-76(122)56(33-47-15-8-5-9-16-47)101-73(119)52(17-10-27-90-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,117)(H,93,126)(H,94,118)(H,96,113)(H,97,114)(H,98,116)(H,99,125)(H,100,123)(H,101,119)(H,102,120)(H,103,121)(H,104,122)(H,105,124)(H,128,129)(H4,87,88,90)/t45-,51+,52+,53-,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 OOFNNKIMGCCHQM-WTYSHWNFSA-N 50270810 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-sulfanylbutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507004 IgG receptor FcRn large subunit p51 Homo sapiens 3900 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270810&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935196 104115872 CHEMBL507004 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415590 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C81H115N23O21S2/c1-43(2)30-53(72(116)99-57(33-48-21-23-50(106)24-22-48)79(123)104-29-12-19-60(104)77(121)101-58(40-126)75(119)93-44(3)68(112)91-39-66(111)103-28-13-20-61(103)80(124)125)94-64(109)37-88-63(108)36-89-70(114)54(31-46-14-7-5-8-15-46)97-74(118)56(34-49-35-86-42-92-49)95-65(110)38-90-78(122)67(45(4)105)102-76(120)59(41-127)100-73(117)55(32-47-16-9-6-10-17-47)98-71(115)52(18-11-27-87-81(84)85)96-69(113)51(82)25-26-62(83)107/h5-10,14-17,21-24,35,42-45,51-61,67,105-106,126-127H,11-13,18-20,25-34,36-41,82H2,1-4H3,(H2,83,107)(H,86,92)(H,88,108)(H,89,114)(H,90,122)(H,91,112)(H,93,119)(H,94,109)(H,95,110)(H,96,113)(H,97,118)(H,98,115)(H,99,116)(H,100,117)(H,101,121)(H,102,120)(H,124,125)(H4,84,85,87)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,67-/m0/s1 PPIIPSJYNJFJCC-RBZKBCOGSA-N 50270809 CHEMBL525060::QRFCTGHFGGLYPCAGP IgG receptor FcRn large subunit p51 Homo sapiens 8000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270809&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935195 104115871 CHEMBL525060 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415591 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C80H114N24O22S2/c1-41(2)27-51(73(119)99-53(30-46-19-21-48(106)22-20-46)72(118)93-42(3)67(113)101-57(38-127)76(122)100-56(32-61(83)108)70(116)91-37-65(112)104-26-12-18-59(104)79(125)126)94-63(110)35-88-62(109)34-89-69(115)52(28-44-13-7-5-8-14-44)97-75(121)55(31-47-33-86-40-92-47)95-64(111)36-90-78(124)66(43(4)105)103-77(123)58(39-128)102-74(120)54(29-45-15-9-6-10-16-45)98-71(117)50(17-11-25-87-80(84)85)96-68(114)49(81)23-24-60(82)107/h5-10,13-16,19-22,33,40-43,49-59,66,105-106,127-128H,11-12,17-18,23-32,34-39,81H2,1-4H3,(H2,82,107)(H2,83,108)(H,86,92)(H,88,109)(H,89,115)(H,90,124)(H,91,116)(H,93,118)(H,94,110)(H,95,111)(H,96,114)(H,97,121)(H,98,117)(H,99,119)(H,100,122)(H,101,113)(H,102,120)(H,103,123)(H,125,126)(H4,84,85,87)/t42-,43+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1 RTSXQTGNHNOUMB-BPXGOGJQSA-N 50270808 CHEMBL524483::QRFCTGHFGGLYACNGP IgG receptor FcRn large subunit p51 Homo sapiens 14000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270808&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935194 104115870 CHEMBL524483 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415592 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O21S2/c1-39(2)26-47(67(112)89-40(3)74(119)100-25-12-19-54(100)72(117)97-52(36-122)70(115)95-51(30-57(79)103)65(110)87-35-61(107)99-24-13-20-55(99)75(120)121)90-59(105)33-84-58(104)32-85-64(109)48(27-42-14-7-5-8-15-42)93-69(114)50(29-44-31-82-38-88-44)91-60(106)34-86-73(118)62(41(4)101)98-71(116)53(37-123)96-68(113)49(28-43-16-9-6-10-17-43)94-66(111)46(18-11-23-83-76(80)81)92-63(108)45(77)21-22-56(78)102/h5-10,14-17,31,38-41,45-55,62,101,122-123H,11-13,18-30,32-37,77H2,1-4H3,(H2,78,102)(H2,79,103)(H,82,88)(H,84,104)(H,85,109)(H,86,118)(H,87,110)(H,89,112)(H,90,105)(H,91,106)(H,92,108)(H,93,114)(H,94,111)(H,95,115)(H,96,113)(H,97,117)(H,98,116)(H,120,121)(H4,80,81,83)/t40-,41+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 AQYIGFNEVYSYMR-CIBQCEIUSA-N 50270807 CHEMBL524301::QRFCTGHFGGLAPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270807&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935193 104115869 CHEMBL524301 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415593 C[C@@H](O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H110N24O22S2/c1-41(66(112)98-54(30-45-19-21-47(105)22-20-45)77(123)103-27-10-17-57(103)75(121)100-55(38-126)73(119)97-53(32-60(82)107)69(115)90-37-64(111)102-26-11-18-58(102)78(124)125)92-62(109)35-87-61(108)34-88-68(114)50(28-43-12-5-3-6-13-43)95-72(118)52(31-46-33-85-40-91-46)93-63(110)36-89-76(122)65(42(2)104)101-74(120)56(39-127)99-71(117)51(29-44-14-7-4-8-15-44)96-70(116)49(16-9-25-86-79(83)84)94-67(113)48(80)23-24-59(81)106/h3-8,12-15,19-22,33,40-42,48-58,65,104-105,126-127H,9-11,16-18,23-32,34-39,80H2,1-2H3,(H2,81,106)(H2,82,107)(H,85,91)(H,87,108)(H,88,114)(H,89,122)(H,90,115)(H,92,109)(H,93,110)(H,94,113)(H,95,118)(H,96,116)(H,97,119)(H,98,112)(H,99,117)(H,100,121)(H,101,120)(H,124,125)(H4,83,84,86)/t41-,42+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,65-/m0/s1 WWJNRJDIESOSSX-PTCAJRAWSA-N 50270806 CHEMBL527054::QRFCTGHFGGAYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 26000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270806&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935192 104115868 CHEMBL527054 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415594 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)98-69(115)44(3)95-65(112)37-91-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)96-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,117)(H,92,126)(H,93,118)(H,95,112)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 NVLFUIQQQXPSCK-ULOXDNNXSA-N 50270805 CHEMBL500525::QRFCTGHFGALYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 120000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270805&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935191 104115867 CHEMBL500525 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415595 CC(C)C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)71(117)93-39-67(114)106-28-13-20-62(106)82(128)129)96-65(112)37-91-69(115)44(3)95-73(119)54(31-46-14-7-5-8-15-46)100-76(122)56(34-49-36-89-42-94-49)97-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)99-72(118)52(18-11-27-90-83(87)88)98-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,115)(H,92,126)(H,93,117)(H,95,119)(H,96,112)(H,97,113)(H,98,116)(H,99,118)(H,100,122)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 HROBHVURICMOFT-ULOXDNNXSA-N 50270804 CHEMBL504968::QRFCTGHFAGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270804&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935190 104115866 CHEMBL504968 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415596 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O22S2/c1-38(2)25-47(68(114)95-51(27-42-16-18-44(102)19-17-42)74(120)100-24-9-14-54(100)72(118)97-52(35-123)70(116)94-50(29-57(79)104)65(111)87-34-61(108)99-23-10-15-55(99)75(121)122)90-59(106)32-84-58(105)31-85-63(109)39(3)89-67(113)49(28-43-30-82-37-88-43)91-60(107)33-86-73(119)62(40(4)101)98-71(117)53(36-124)96-69(115)48(26-41-11-6-5-7-12-41)93-66(112)46(13-8-22-83-76(80)81)92-64(110)45(77)20-21-56(78)103/h5-7,11-12,16-19,30,37-40,45-55,62,101-102,123-124H,8-10,13-15,20-29,31-36,77H2,1-4H3,(H2,78,103)(H2,79,104)(H,82,88)(H,84,105)(H,85,109)(H,86,119)(H,87,111)(H,89,113)(H,90,106)(H,91,107)(H,92,110)(H,93,112)(H,94,116)(H,95,114)(H,96,115)(H,97,118)(H,98,117)(H,121,122)(H4,80,81,83)/t39-,40+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 GOKZXJDBZOKFTE-PVLMKORCSA-N 50270803 CHEMBL526348::QRFCTGHAGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270803&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935189 104115865 CHEMBL526348 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415597 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H114N22O22S2/c1-41(2)30-50(71(115)96-54(33-46-21-23-47(103)24-22-46)77(121)101-29-12-19-57(101)75(119)98-55(39-124)73(117)95-53(34-60(82)105)69(113)89-38-64(109)100-28-13-20-58(100)78(122)123)91-63(108)36-86-61(106)35-87-68(112)51(31-44-14-7-5-8-15-44)93-66(110)42(3)90-62(107)37-88-76(120)65(43(4)102)99-74(118)56(40-125)97-72(116)52(32-45-16-9-6-10-17-45)94-70(114)49(18-11-27-85-79(83)84)92-67(111)48(80)25-26-59(81)104/h5-10,14-17,21-24,41-43,48-58,65,102-103,124-125H,11-13,18-20,25-40,80H2,1-4H3,(H2,81,104)(H2,82,105)(H,86,106)(H,87,112)(H,88,120)(H,89,113)(H,90,107)(H,91,108)(H,92,111)(H,93,110)(H,94,114)(H,95,117)(H,96,115)(H,97,116)(H,98,119)(H,99,118)(H,122,123)(H4,83,84,85)/t42-,43+,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,65-/m0/s1 KZNISIFFYHJCFV-DCUVTQBESA-N 50270802 CHEMBL501035::QRFCTGAFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270802&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935188 104115864 CHEMBL501035 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415598 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)96-66(113)38-91-65(112)37-92-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)98-69(115)44(3)95-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,112)(H,92,117)(H,93,118)(H,95,126)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-/m0/s1 BAXZNYMLTXZPTP-ULOXDNNXSA-N 50270801 CHEMBL524711::QRFCTAHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270801&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935187 104115863 CHEMBL524711 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415599 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C81H114N24O21S2/c1-43(2)29-52(73(118)101-57(32-47-20-22-49(106)23-21-47)79(124)105-28-11-18-60(105)78(123)103-59(41-128)77(122)100-56(34-63(84)108)71(116)92-39-67(112)104-27-12-19-61(104)80(125)126)95-65(110)37-89-64(109)36-91-70(115)53(30-45-13-6-4-7-14-45)98-75(120)55(33-48-35-87-42-93-48)96-66(111)38-90-68(113)44(3)94-76(121)58(40-127)102-74(119)54(31-46-15-8-5-9-16-46)99-72(117)51(17-10-26-88-81(85)86)97-69(114)50(82)24-25-62(83)107/h4-9,13-16,20-23,35,42-44,50-61,106,127-128H,10-12,17-19,24-34,36-41,82H2,1-3H3,(H2,83,107)(H2,84,108)(H,87,93)(H,89,109)(H,90,113)(H,91,115)(H,92,116)(H,94,121)(H,95,110)(H,96,111)(H,97,114)(H,98,120)(H,99,117)(H,100,122)(H,101,118)(H,102,119)(H,103,123)(H,125,126)(H4,85,86,88)/t44-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-/m0/s1 PPQQQQUDHBZTAW-ZUNNVFAGSA-N 50270800 CHEMBL510017::QRFCAGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 4900 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270800&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935186 104115862 CHEMBL510017 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415600 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C76H112N24O22S2/c1-38(2)25-47(68(114)95-51(27-42-16-18-44(102)19-17-42)74(120)100-24-9-14-54(100)72(118)97-52(35-123)70(116)94-50(29-57(79)104)66(112)87-34-61(108)99-23-10-15-55(99)75(121)122)90-59(106)32-84-58(105)31-85-65(111)48(26-41-11-6-5-7-12-41)93-69(115)49(28-43-30-82-37-88-43)91-60(107)33-86-73(119)62(40(4)101)98-71(117)53(36-124)96-63(109)39(3)89-67(113)46(13-8-22-83-76(80)81)92-64(110)45(77)20-21-56(78)103/h5-7,11-12,16-19,30,37-40,45-55,62,101-102,123-124H,8-10,13-15,20-29,31-36,77H2,1-4H3,(H2,78,103)(H2,79,104)(H,82,88)(H,84,105)(H,85,111)(H,86,119)(H,87,112)(H,89,113)(H,90,106)(H,91,107)(H,92,110)(H,93,115)(H,94,116)(H,95,114)(H,96,109)(H,97,118)(H,98,117)(H,121,122)(H4,80,81,83)/t39-,40+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,62-/m0/s1 WZFJFPHZIPHUTB-PVLMKORCSA-N 50270799 CHEMBL504145::QRACTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 28000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270799&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935185 104115861 CHEMBL504145 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415601 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C79H109N21O22S2/c1-41(2)27-50(71(113)95-55(30-46-19-21-48(102)22-20-46)78(120)100-26-11-17-58(100)76(118)97-56(38-123)74(116)94-54(32-61(82)104)70(112)87-37-65(108)99-25-12-18-59(99)79(121)122)90-63(106)35-84-62(105)34-85-69(111)51(28-44-13-7-5-8-14-44)93-73(115)53(31-47-33-83-40-88-47)91-64(107)36-86-77(119)66(43(4)101)98-75(117)57(39-124)96-72(114)52(29-45-15-9-6-10-16-45)92-67(109)42(3)89-68(110)49(80)23-24-60(81)103/h5-10,13-16,19-22,33,40-43,49-59,66,101-102,123-124H,11-12,17-18,23-32,34-39,80H2,1-4H3,(H2,81,103)(H2,82,104)(H,83,88)(H,84,105)(H,85,111)(H,86,119)(H,87,112)(H,89,110)(H,90,106)(H,91,107)(H,92,109)(H,93,115)(H,94,116)(H,95,113)(H,96,114)(H,97,118)(H,98,117)(H,121,122)/t42-,43+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1 JTWFFKOCJDFBHW-BPXGOGJQSA-N 50270798 CHEMBL508486::QAFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 7700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270798&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585689 104115860 CHEMBL508486 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415602 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H124N24O22S2/c1-46(2)34-55(76(123)105-60(37-50-24-26-52(113)27-25-50)84(131)111-33-14-22-63(111)81(128)106-61(44-134)79(126)103-59(39-66(90)115)74(121)97-43-69(118)110-32-15-23-64(110)85(132)133)104-80(127)62-21-13-31-109(62)68(117)42-96-73(120)56(35-48-16-8-6-9-17-48)101-77(124)58(38-51-40-93-45-98-51)99-67(116)41-95-82(129)70(47(3)112)107-83(130)71(87(4,5)135)108-78(125)57(36-49-18-10-7-11-19-49)102-75(122)54(20-12-30-94-86(91)92)100-72(119)53(88)28-29-65(89)114/h6-11,16-19,24-27,40,45-47,53-64,70-71,112-113,134-135H,12-15,20-23,28-39,41-44,88H2,1-5H3,(H2,89,114)(H2,90,115)(H,93,98)(H,95,129)(H,96,120)(H,97,121)(H,99,116)(H,100,119)(H,101,124)(H,102,122)(H,103,126)(H,104,127)(H,105,123)(H,106,128)(H,107,130)(H,108,125)(H,132,133)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62-,63+,64+,70+,71-/m1/s1 GRDKPLKVGVVKJL-QTLAHMFMSA-N 50270838 CHEMBL508564 IgG receptor FcRn large subunit p51 Homo sapiens 230 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270838&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935219 104115900 CHEMBL508564 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415603 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58-,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-CFVPATMLSA-N 50270902 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2R)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL446301 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270902&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935252 104115945 CHEMBL446301 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415604 CC(C)C[C@@H](NC(=O)CNC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53-,54-,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-OARSYXCYSA-N 50270901 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2R)-2-(2-{2-[(2R)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501492 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270901&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935251 104115944 CHEMBL501492 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415605 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54-,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-FSUBTDEOSA-N 50270900 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2R)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503695 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270900&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935250 104115943 CHEMBL503695 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415606 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68-,69+/m1/s1 XMBRKVYGPTUTDQ-REHCMJGESA-N 50270899 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2R,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506091 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270899&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935249 104115942 CHEMBL506091 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415607 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55-,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-JXHPJOSXSA-N 50270898 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506646 IgG receptor FcRn large subunit p51 Homo sapiens 11400 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270898&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935248 104115941 CHEMBL506646 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415608 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52-,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-GXYFPZCESA-N 50270897 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501541 IgG receptor FcRn large subunit p51 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270897&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935247 104115940 CHEMBL501541 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415609 CC(C)C[C@H](NC(=O)CN(C)C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-55(75(122)104-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)79(126)105-61(43-133)78(125)103-59(38-65(89)114)72(119)95-41-68(117)109-31-16-23-63(109)84(131)132)99-67(116)42-108(7)82(129)46(3)97-74(121)56(34-48-17-10-8-11-18-48)102-76(123)58(37-51-39-92-44-96-51)98-66(115)40-94-80(127)69(47(4)111)106-81(128)70(86(5,6)134)107-77(124)57(35-49-19-12-9-13-20-49)101-73(120)54(21-14-30-93-85(90)91)100-71(118)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,127)(H,95,119)(H,97,121)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1 WVVLRGIVQCLOAZ-UODRXTJASA-N 50270896 CHEMBL525636 IgG receptor FcRn large subunit p51 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270896&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935246 104115939 CHEMBL525636 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415610 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69+,70+,71+,76+,77-/m1/s1 WGJHMCNUSNAKEE-RRTVRWFKSA-N 50270895 CHEMBL526337 IgG receptor FcRn large subunit p51 Homo sapiens 22000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270895&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935245 104115938 CHEMBL526337 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415611 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)32-54(75(122)104-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)105-60(42-132)78(125)103-58(37-64(88)113)73(120)95-41-67(116)108-30-15-22-62(108)83(130)131)100-70(117)45(3)97-65(114)39-93-72(119)55(33-47-16-9-7-10-17-47)101-76(123)57(36-50-38-91-43-96-50)98-66(115)40-94-80(127)68(46(4)110)106-81(128)69(85(5,6)133)107-77(124)56(34-48-18-11-8-12-19-48)102-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,43-46,52-62,68-69,110-111,132-133H,13-15,20-22,27-37,39-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,119)(H,94,127)(H,95,120)(H,97,114)(H,98,115)(H,99,118)(H,100,117)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 PODDJIVEEGWXML-LVOPMODUSA-N 50270884 CHEMBL506263 IgG receptor FcRn large subunit p51 Homo sapiens 480 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270884&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935234 104115927 CHEMBL506263 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415612 CC(C)C[C@H](NC(=O)CNC(=O)C(C)(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-54(73(121)104-59(36-49-24-26-51(112)27-25-49)81(129)110-32-15-22-61(110)78(126)105-60(43-133)76(124)103-58(38-64(89)114)71(119)95-42-67(117)109-31-16-23-62(109)82(130)131)98-66(116)41-96-83(132)85(4,5)108-77(125)56(35-48-19-12-9-13-20-48)102-74(122)57(37-50-39-92-44-97-50)99-65(115)40-94-79(127)68(46(3)111)106-80(128)69(86(6,7)134)107-75(123)55(34-47-17-10-8-11-18-47)101-72(120)53(21-14-30-93-84(90)91)100-70(118)52(87)28-29-63(88)113/h8-13,17-20,24-27,39,44-46,52-62,68-69,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,127)(H,95,119)(H,96,132)(H,98,116)(H,99,115)(H,100,118)(H,101,120)(H,102,122)(H,103,124)(H,104,121)(H,105,126)(H,106,128)(H,107,123)(H,108,125)(H,130,131)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 OOZNCZPFBGELNC-OJSMXDMESA-N 50270883 CHEMBL510473 IgG receptor FcRn large subunit p51 Homo sapiens 5200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270883&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935233 104115926 CHEMBL510473 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415613 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O23S2/c1-48(2)35-59(80(128)110-65(39-53-24-28-56(118)29-25-53)88(136)115-34-13-20-67(115)85(133)111-66(46-139)84(132)109-64(41-70(94)120)78(126)101-45-73(123)114-33-14-21-68(114)89(137)138)103-71(121)43-99-77(125)60(38-52-22-26-55(117)27-23-52)106-81(129)61(36-50-15-8-6-9-16-50)108-82(130)63(40-54-42-97-47-102-54)104-72(122)44-100-86(134)74(49(3)116)112-87(135)75(91(4,5)140)113-83(131)62(37-51-17-10-7-11-18-51)107-79(127)58(19-12-32-98-90(95)96)105-76(124)57(92)30-31-69(93)119/h6-11,15-18,22-29,42,47-49,57-68,74-75,116-118,139-140H,12-14,19-21,30-41,43-46,92H2,1-5H3,(H2,93,119)(H2,94,120)(H,97,102)(H,99,125)(H,100,134)(H,101,126)(H,103,121)(H,104,122)(H,105,124)(H,106,129)(H,107,127)(H,108,130)(H,109,132)(H,110,128)(H,111,133)(H,112,135)(H,113,131)(H,137,138)(H4,95,96,98)/t49-,57+,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 HMXZZVMEIUZBHD-QLQLPVARSA-N 50270882 CHEMBL526187 IgG receptor FcRn large subunit p51 Homo sapiens 320 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270882&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935232 104115925 CHEMBL526187 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415614 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O22S2/c1-49(2)36-59(80(127)110-65(40-54-27-29-56(117)30-28-54)88(135)115-35-16-25-67(115)85(132)111-66(47-138)84(131)109-64(42-70(94)119)78(125)101-46-73(122)114-34-17-26-68(114)89(136)137)103-71(120)44-99-77(124)60(37-51-18-9-6-10-19-51)106-81(128)61(38-52-20-11-7-12-21-52)108-82(129)63(41-55-43-97-48-102-55)104-72(121)45-100-86(133)74(50(3)116)112-87(134)75(91(4,5)139)113-83(130)62(39-53-22-13-8-14-23-53)107-79(126)58(24-15-33-98-90(95)96)105-76(123)57(92)31-32-69(93)118/h6-14,18-23,27-30,43,48-50,57-68,74-75,116-117,138-139H,15-17,24-26,31-42,44-47,92H2,1-5H3,(H2,93,118)(H2,94,119)(H,97,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,126)(H,108,129)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,95,96,98)/t50-,57+,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 MOFZVRUXPRVWJW-XVQGAXIUSA-N 50270850 CHEMBL525014 IgG receptor FcRn large subunit p51 Homo sapiens 510 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270850&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935231 104115912 CHEMBL525014 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415615 CC[C@H](C)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H128N24O22S2/c1-8-47(4)70(82(129)96-41-67(117)100-56(34-46(2)3)76(123)106-61(37-51-25-27-53(114)28-26-51)85(132)112-33-16-23-63(112)81(128)107-62(44-135)80(127)105-60(39-66(91)116)74(121)98-43-69(119)111-32-17-24-64(111)86(133)134)108-78(125)57(35-49-18-11-9-12-19-49)104-77(124)59(38-52-40-94-45-99-52)101-68(118)42-97-83(130)71(48(5)113)109-84(131)72(88(6,7)136)110-79(126)58(36-50-20-13-10-14-21-50)103-75(122)55(22-15-31-95-87(92)93)102-73(120)54(89)29-30-65(90)115/h9-14,18-21,25-28,40,45-48,54-64,70-72,113-114,135-136H,8,15-17,22-24,29-39,41-44,89H2,1-7H3,(H2,90,115)(H2,91,116)(H,94,99)(H,96,129)(H,97,130)(H,98,121)(H,100,117)(H,101,118)(H,102,120)(H,103,122)(H,104,124)(H,105,127)(H,106,123)(H,107,128)(H,108,125)(H,109,131)(H,110,126)(H,133,134)(H4,92,93,95)/t47-,48+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,70+,71-,72+/m0/s1 GLRIWGCDNHGJTN-FYGOBARVSA-N 50270849 CHEMBL525045 IgG receptor FcRn large subunit p51 Homo sapiens 2600 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270849&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935230 104115911 CHEMBL525045 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415616 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H124N26O22S2/c1-46(2)31-56(77(126)109-62(34-50-22-24-53(116)25-23-50)85(134)114-30-13-20-64(114)82(131)110-63(43-137)81(130)108-61(37-67(91)118)75(124)99-42-70(121)113-29-14-21-65(113)86(135)136)102-68(119)40-97-74(123)59(35-51-38-94-44-100-51)107-78(127)57(32-48-15-8-6-9-16-48)106-79(128)60(36-52-39-95-45-101-52)103-69(120)41-98-83(132)71(47(3)115)111-84(133)72(88(4,5)138)112-80(129)58(33-49-17-10-7-11-18-49)105-76(125)55(19-12-28-96-87(92)93)104-73(122)54(89)26-27-66(90)117/h6-11,15-18,22-25,38-39,44-47,54-65,71-72,115-116,137-138H,12-14,19-21,26-37,40-43,89H2,1-5H3,(H2,90,117)(H2,91,118)(H,94,100)(H,95,101)(H,97,123)(H,98,132)(H,99,124)(H,102,119)(H,103,120)(H,104,122)(H,105,125)(H,106,128)(H,107,127)(H,108,130)(H,109,126)(H,110,131)(H,111,133)(H,112,129)(H,135,136)(H4,92,93,96)/t47-,54+,55+,56+,57+,58+,59-,60+,61+,62+,63+,64+,65+,71+,72-/m1/s1 SEFGHKFHGKGLFZ-SVYDDRGQSA-N 50270848 CHEMBL504493 IgG receptor FcRn large subunit p51 Homo sapiens 410 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270848&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935229 104115910 CHEMBL504493 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415617 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H129N27O22S2/c1-46(2)34-56(76(127)110-61(37-50-24-26-52(117)27-25-50)84(135)115-33-14-22-63(115)81(132)111-62(44-138)80(131)109-60(39-66(91)119)74(125)101-43-69(122)114-32-15-23-64(114)85(136)137)103-67(120)41-99-73(124)54(20-12-30-97-86(92)93)106-77(128)57(35-48-16-8-6-9-17-48)108-78(129)59(38-51-40-96-45-102-51)104-68(121)42-100-82(133)70(47(3)116)112-83(134)71(88(4,5)139)113-79(130)58(36-49-18-10-7-11-19-49)107-75(126)55(21-13-31-98-87(94)95)105-72(123)53(89)28-29-65(90)118/h6-11,16-19,24-27,40,45-47,53-64,70-71,116-117,138-139H,12-15,20-23,28-39,41-44,89H2,1-5H3,(H2,90,118)(H2,91,119)(H,96,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,126)(H,108,129)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,92,93,97)(H4,94,95,98)/t47-,53+,54-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,70+,71-/m1/s1 KFPQUNOLKHJNOL-VKIHZXIPSA-N 50270847 CHEMBL524856 IgG receptor FcRn large subunit p51 Homo sapiens 310 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270847&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935228 104115909 CHEMBL524856 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415618 CC(C)C[C@H](NC(=O)CNC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H124N24O22S2/c1-46(2)34-55(75(122)104-60(37-50-24-26-52(113)27-25-50)84(131)111-33-14-22-63(111)80(127)106-61(44-134)78(125)103-58(39-66(90)115)73(120)97-43-69(118)109-31-15-23-64(109)85(132)133)99-67(116)41-95-79(126)62-21-13-32-110(62)83(130)59(36-49-18-10-7-11-19-49)105-76(123)57(38-51-40-93-45-98-51)100-68(117)42-96-81(128)70(47(3)112)107-82(129)71(87(4,5)135)108-77(124)56(35-48-16-8-6-9-17-48)102-74(121)54(20-12-30-94-86(91)92)101-72(119)53(88)28-29-65(89)114/h6-11,16-19,24-27,40,45-47,53-64,70-71,112-113,134-135H,12-15,20-23,28-39,41-44,88H2,1-5H3,(H2,89,114)(H2,90,115)(H,93,98)(H,95,126)(H,96,128)(H,97,120)(H,99,116)(H,100,117)(H,101,119)(H,102,121)(H,103,125)(H,104,122)(H,105,123)(H,106,127)(H,107,129)(H,108,124)(H,132,133)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62-,63+,64+,70+,71-/m1/s1 JUTOVPGZTYTSLV-QTLAHMFMSA-N 50270846 CHEMBL510817 IgG receptor FcRn large subunit p51 Homo sapiens 790 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270846&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935227 104115908 CHEMBL510817 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415619 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H122N24O24S2/c1-44(2)31-53(75(124)105-59(34-48-22-24-50(112)25-23-48)83(132)110-30-13-20-61(110)80(129)106-60(42-135)79(128)103-57(36-64(89)114)72(121)96-41-67(117)109-29-14-21-62(109)84(133)134)98-65(115)39-94-73(122)58(37-68(118)119)104-76(125)54(32-46-15-8-6-9-16-46)102-77(126)56(35-49-38-92-43-97-49)99-66(116)40-95-81(130)69(45(3)111)107-82(131)70(86(4,5)136)108-78(127)55(33-47-17-10-7-11-18-47)101-74(123)52(19-12-28-93-85(90)91)100-71(120)51(87)26-27-63(88)113/h6-11,15-18,22-25,38,43-45,51-62,69-70,111-112,135-136H,12-14,19-21,26-37,39-42,87H2,1-5H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,122)(H,95,130)(H,96,121)(H,98,115)(H,99,116)(H,100,120)(H,101,123)(H,102,126)(H,103,128)(H,104,125)(H,105,124)(H,106,129)(H,107,131)(H,108,127)(H,118,119)(H,133,134)(H4,90,91,93)/t45-,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,61+,62+,69+,70-/m1/s1 GAUDEOLZZHYASR-IDWCDBDKSA-N 50270845 CHEMBL451424 IgG receptor FcRn large subunit p51 Homo sapiens 580 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270845&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935226 104115907 CHEMBL451424 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415620 CC(C)C[C@H](NC(=O)C(C)(C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-54(74(122)103-59(36-49-24-26-51(112)27-25-49)81(129)110-32-15-22-61(110)78(126)104-60(43-133)77(125)102-58(38-64(89)114)72(120)96-42-67(117)109-31-16-23-62(109)82(130)131)105-83(132)85(4,5)108-66(116)41-94-71(119)55(34-47-17-10-8-11-18-47)100-75(123)57(37-50-39-92-44-97-50)98-65(115)40-95-79(127)68(46(3)111)106-80(128)69(86(6,7)134)107-76(124)56(35-48-19-12-9-13-20-48)101-73(121)53(21-14-30-93-84(90)91)99-70(118)52(87)28-29-63(88)113/h8-13,17-20,24-27,39,44-46,52-62,68-69,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,132)(H,106,128)(H,107,124)(H,108,116)(H,130,131)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 IBXUOXAWRBNUSK-OJSMXDMESA-N 50270844 CHEMBL504266 IgG receptor FcRn large subunit p51 Homo sapiens 480 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270844&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935225 104115906 CHEMBL504266 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415621 CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O23S2/c1-48(2)35-59(80(128)110-65(39-53-24-28-56(118)29-25-53)88(136)115-34-13-20-67(115)85(133)111-66(46-139)84(132)109-64(41-70(94)120)78(126)101-45-73(123)114-33-14-21-68(114)89(137)138)106-81(129)61(38-52-22-26-55(117)27-23-52)103-71(121)43-99-77(125)60(36-50-15-8-6-9-16-50)107-82(130)63(40-54-42-97-47-102-54)104-72(122)44-100-86(134)74(49(3)116)112-87(135)75(91(4,5)140)113-83(131)62(37-51-17-10-7-11-18-51)108-79(127)58(19-12-32-98-90(95)96)105-76(124)57(92)30-31-69(93)119/h6-11,15-18,22-29,42,47-49,57-68,74-75,116-118,139-140H,12-14,19-21,30-41,43-46,92H2,1-5H3,(H2,93,119)(H2,94,120)(H,97,102)(H,99,125)(H,100,134)(H,101,126)(H,103,121)(H,104,122)(H,105,124)(H,106,129)(H,107,130)(H,108,127)(H,109,132)(H,110,128)(H,111,133)(H,112,135)(H,113,131)(H,137,138)(H4,95,96,98)/t49-,57+,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 FHNANAOGEJSYFI-HQWAHVIOSA-N 50270843 CHEMBL524908 IgG receptor FcRn large subunit p51 Homo sapiens 1500 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270843&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935224 104115905 CHEMBL524908 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415622 CC(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O22S2/c1-49(2)36-59(80(127)110-65(40-54-27-29-56(117)30-28-54)88(135)115-35-16-25-67(115)85(132)111-66(47-138)84(131)109-64(42-70(94)119)78(125)101-46-73(122)114-34-17-26-68(114)89(136)137)106-81(128)61(38-52-20-11-7-12-21-52)103-71(120)44-99-77(124)60(37-51-18-9-6-10-19-51)107-82(129)63(41-55-43-97-48-102-55)104-72(121)45-100-86(133)74(50(3)116)112-87(134)75(91(4,5)139)113-83(130)62(39-53-22-13-8-14-23-53)108-79(126)58(24-15-33-98-90(95)96)105-76(123)57(92)31-32-69(93)118/h6-14,18-23,27-30,43,48-50,57-68,74-75,116-117,138-139H,15-17,24-26,31-42,44-47,92H2,1-5H3,(H2,93,118)(H2,94,119)(H,97,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,129)(H,108,126)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,95,96,98)/t50-,57+,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 ZPJFDXPMNYPTKD-DJTHZEPZSA-N 50270842 CHEMBL508983 IgG receptor FcRn large subunit p51 Homo sapiens 1700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270842&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935223 104115904 CHEMBL508983 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415623 CC[C@H](C)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H128N24O22S2/c1-8-47(4)70(83(130)105-56(34-46(2)3)77(124)106-61(37-51-25-27-53(114)28-26-51)85(132)112-33-16-23-63(112)81(128)107-62(44-135)80(127)104-60(39-66(91)116)75(122)98-43-69(119)111-32-17-24-64(111)86(133)134)108-68(118)42-96-74(121)57(35-49-18-11-9-12-19-49)102-78(125)59(38-52-40-94-45-99-52)100-67(117)41-97-82(129)71(48(5)113)109-84(131)72(88(6,7)136)110-79(126)58(36-50-20-13-10-14-21-50)103-76(123)55(22-15-31-95-87(92)93)101-73(120)54(89)29-30-65(90)115/h9-14,18-21,25-28,40,45-48,54-64,70-72,113-114,135-136H,8,15-17,22-24,29-39,41-44,89H2,1-7H3,(H2,90,115)(H2,91,116)(H,94,99)(H,96,121)(H,97,129)(H,98,122)(H,100,117)(H,101,120)(H,102,125)(H,103,123)(H,104,127)(H,105,130)(H,106,124)(H,107,128)(H,108,118)(H,109,131)(H,110,126)(H,133,134)(H4,92,93,95)/t47-,48+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,70+,71-,72+/m0/s1 UENMCFLPLIZIGA-FYGOBARVSA-N 50270841 CHEMBL454229 IgG receptor FcRn large subunit p51 Homo sapiens 2200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270841&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935222 104115903 CHEMBL454229 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415624 CC(C)C[C@H](NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H124N26O22S2/c1-46(2)31-56(77(126)109-62(34-50-22-24-53(116)25-23-50)85(134)114-30-13-20-64(114)82(131)110-63(43-137)81(130)108-61(37-67(91)118)75(124)99-42-70(121)113-29-14-21-65(113)86(135)136)105-78(127)59(35-51-38-94-44-100-51)102-68(119)40-97-74(123)57(32-48-15-8-6-9-16-48)106-79(128)60(36-52-39-95-45-101-52)103-69(120)41-98-83(132)71(47(3)115)111-84(133)72(88(4,5)138)112-80(129)58(33-49-17-10-7-11-18-49)107-76(125)55(19-12-28-96-87(92)93)104-73(122)54(89)26-27-66(90)117/h6-11,15-18,22-25,38-39,44-47,54-65,71-72,115-116,137-138H,12-14,19-21,26-37,40-43,89H2,1-5H3,(H2,90,117)(H2,91,118)(H,94,100)(H,95,101)(H,97,123)(H,98,132)(H,99,124)(H,102,119)(H,103,120)(H,104,122)(H,105,127)(H,106,128)(H,107,125)(H,108,130)(H,109,126)(H,110,131)(H,111,133)(H,112,129)(H,135,136)(H4,92,93,96)/t47-,54+,55+,56+,57+,58+,59-,60+,61+,62+,63+,64+,65+,71+,72-/m1/s1 XXVWNYAYRJSQGC-SVYDDRGQSA-N 50270840 CHEMBL525040 IgG receptor FcRn large subunit p51 Homo sapiens 2000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270840&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935221 104115902 CHEMBL525040 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415625 CC(C)C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H129N27O22S2/c1-46(2)34-56(77(128)110-61(37-50-24-26-52(117)27-25-50)84(135)115-33-14-22-63(115)81(132)111-62(44-138)80(131)109-60(39-66(91)119)74(125)101-43-69(122)114-32-15-23-64(114)85(136)137)106-75(126)54(20-12-30-97-86(92)93)103-67(120)41-99-73(124)57(35-48-16-8-6-9-17-48)107-78(129)59(38-51-40-96-45-102-51)104-68(121)42-100-82(133)70(47(3)116)112-83(134)71(88(4,5)139)113-79(130)58(36-49-18-10-7-11-19-49)108-76(127)55(21-13-31-98-87(94)95)105-72(123)53(89)28-29-65(90)118/h6-11,16-19,24-27,40,45-47,53-64,70-71,116-117,138-139H,12-15,20-23,28-39,41-44,89H2,1-5H3,(H2,90,118)(H2,91,119)(H,96,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,126)(H,107,129)(H,108,127)(H,109,131)(H,110,128)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,92,93,97)(H4,94,95,98)/t47-,53+,54-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,70+,71-/m1/s1 CMCHQCYGHXEPCM-VKIHZXIPSA-N 50270839 CHEMBL505790 IgG receptor FcRn large subunit p51 Homo sapiens 830 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270839&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935220 104115901 CHEMBL505790 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415626 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H121N25O22S2/c1-44(2)30-55(76(124)106-60(32-47-21-23-50(113)24-22-47)83(131)111-29-12-19-62(111)80(128)107-61(42-134)79(127)105-59(35-65(89)115)74(122)98-41-69(119)110-28-13-20-63(110)84(132)133)100-67(117)39-95-66(116)38-96-73(121)57(33-48-36-94-53-17-10-9-16-51(48)53)104-77(125)58(34-49-37-92-43-99-49)101-68(118)40-97-81(129)70(45(3)112)108-82(130)71(86(4,5)135)109-78(126)56(31-46-14-7-6-8-15-46)103-75(123)54(18-11-27-93-85(90)91)102-72(120)52(87)25-26-64(88)114/h6-10,14-17,21-24,36-37,43-45,52,54-63,70-71,94,112-113,134-135H,11-13,18-20,25-35,38-42,87H2,1-5H3,(H2,88,114)(H2,89,115)(H,92,99)(H,95,116)(H,96,121)(H,97,129)(H,98,122)(H,100,117)(H,101,118)(H,102,120)(H,103,123)(H,104,125)(H,105,127)(H,106,124)(H,107,128)(H,108,130)(H,109,126)(H,132,133)(H4,90,91,93)/t45-,52+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 YCGCFCPNCZJFMK-SQDIJLIXSA-N 50270919 CHEMBL527084 IgG receptor FcRn large subunit p51 Homo sapiens 26000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270919&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935268 104115962 CHEMBL527084 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415627 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)31-52(72(119)101-56(33-46-22-24-49(109)25-23-46)80(127)107-30-13-20-58(107)76(123)102-57(41-130)75(122)100-55(35-61(86)111)70(117)94-40-65(115)106-29-14-21-59(106)81(128)129)96-63(113)38-91-62(112)37-92-78(125)67(47-17-10-7-11-18-47)104-73(120)54(34-48-36-89-42-95-48)97-64(114)39-93-77(124)66(44(3)108)103-79(126)68(83(4,5)131)105-74(121)53(32-45-15-8-6-9-16-45)99-71(118)51(19-12-28-90-82(87)88)98-69(116)50(84)26-27-60(85)110/h6-11,15-18,22-25,36,42-44,50-59,66-68,108-109,130-131H,12-14,19-21,26-35,37-41,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,125)(H,93,124)(H,94,117)(H,96,113)(H,97,114)(H,98,116)(H,99,118)(H,100,122)(H,101,119)(H,102,123)(H,103,126)(H,104,120)(H,105,121)(H,128,129)(H4,87,88,90)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,66+,67+,68-/m1/s1 FSFORDRZUSZFNV-VFPQSOOHSA-N 50270920 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-2-phenylacetamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524692 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270920&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935269 104115963 CHEMBL524692 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415628 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H120N24O22S2/c1-44(2)30-54(74(121)103-57(32-47-21-23-51(111)24-22-47)81(128)108-29-12-19-60(108)78(125)104-59(42-132)76(123)102-56(35-64(88)113)72(119)96-40-68(117)107-28-13-20-61(107)83(130)131)98-66(115)38-93-65(114)37-94-77(124)62-33-48-16-9-10-17-49(48)41-109(62)82(129)58(34-50-36-91-43-97-50)99-67(116)39-95-79(126)69(45(3)110)105-80(127)70(85(4,5)133)106-75(122)55(31-46-14-7-6-8-15-46)101-73(120)53(18-11-27-92-84(89)90)100-71(118)52(86)25-26-63(87)112/h6-10,14-17,21-24,36,43-45,52-62,69-70,110-111,132-133H,11-13,18-20,25-35,37-42,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,124)(H,95,126)(H,96,119)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,121)(H,104,125)(H,105,127)(H,106,122)(H,130,131)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70+/m1/s1 RRTFOICYEPNINN-UXGAPGMISA-N 50270921 CHEMBL498892 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270921&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935270 104115964 CHEMBL498892 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415629 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1Cl)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)27-48(64(104)90-52(29-41-19-21-44(96)22-20-41)70(110)94-26-12-18-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)50(30-42-15-9-10-16-45(42)74)89-65(105)51(31-43-32-79-37-84-43)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)49(28-40-13-7-6-8-14-40)88-63(103)47(17-11-25-80-72(77)78)87-61(101)46(75)23-24-55(76)97/h6-10,13-16,19-22,32,37-39,46-54,59-60,95-96,113-114H,11-12,17-18,23-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,103)(H,89,105)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 DPKBOVLGLVWKOG-YZOWQPKWSA-N 50270922 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(2-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525594 IgG receptor FcRn large subunit p51 Homo sapiens 4000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270922&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935271 104115965 CHEMBL525594 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415630 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)26-48(64(104)90-52(29-41-18-20-45(96)21-19-41)70(110)94-25-11-17-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)49(30-42-14-9-15-43(74)27-42)88-65(105)51(31-44-32-79-37-84-44)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)50(28-40-12-7-6-8-13-40)89-63(103)47(16-10-24-80-72(77)78)87-61(101)46(75)22-23-55(76)97/h6-9,12-15,18-21,27,32,37-39,46-54,59-60,95-96,113-114H,10-11,16-17,22-26,28-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,105)(H,89,103)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 SQAMZKNFJMVLPC-YZOWQPKWSA-N 50270923 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(3-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL508126 IgG receptor FcRn large subunit p51 Homo sapiens 3700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270923&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935272 104115966 CHEMBL508126 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415631 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O23S2/c1-44(2)31-55(76(125)106-60(34-49-20-24-52(114)25-21-49)83(132)111-30-11-16-62(111)80(129)107-61(42-135)79(128)105-59(36-65(89)116)74(123)97-41-69(120)110-29-12-17-63(110)84(133)134)100-67(118)39-94-66(117)38-95-73(122)56(33-48-18-22-50(23-19-48)99-46(4)113)103-77(126)58(35-51-37-92-43-98-51)101-68(119)40-96-81(130)70(45(3)112)108-82(131)71(86(5,6)136)109-78(127)57(32-47-13-8-7-9-14-47)104-75(124)54(15-10-28-93-85(90)91)102-72(121)53(87)26-27-64(88)115/h7-9,13-14,18-25,37,43-45,53-63,70-71,112,114,135-136H,10-12,15-17,26-36,38-42,87H2,1-6H3,(H2,88,115)(H2,89,116)(H,92,98)(H,94,117)(H,95,122)(H,96,130)(H,97,123)(H,99,113)(H,100,118)(H,101,119)(H,102,121)(H,103,126)(H,104,124)(H,105,128)(H,106,125)(H,107,129)(H,108,131)(H,109,127)(H,133,134)(H4,90,91,93)/t45-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 JPKQWCGCSKXPJW-CJDQEJCYSA-N 50270918 CHEMBL444687 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270918&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935267 104115961 CHEMBL444687 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415632 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H126N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h7,10-11,17-18,22-25,37,43-46,51-61,68-69,109-110,131-132H,6,8-9,12-16,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 SMJLMHPTWAXYSF-JFFCSCEESA-N 50270917 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-cyclohexylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL527080 IgG receptor FcRn large subunit p51 Homo sapiens 31000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270917&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935266 104115960 CHEMBL527080 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415633 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)33-55(75(122)104-59(35-49-22-25-51(111)26-23-49)82(129)109-32-13-20-61(109)79(126)105-60(43-132)78(125)103-58(37-64(88)113)73(120)96-42-68(117)108-31-14-21-62(108)83(130)131)98-66(115)40-93-65(114)39-94-72(119)54(28-24-47-15-8-6-9-16-47)101-76(123)57(36-50-38-91-44-97-50)99-67(116)41-95-80(127)69(46(3)110)106-81(128)70(85(4,5)133)107-77(124)56(34-48-17-10-7-11-18-48)102-74(121)53(19-12-30-92-84(89)90)100-71(118)52(86)27-29-63(87)112/h6-11,15-18,22-23,25-26,38,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,24,27-37,39-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 NTNKRJXQUHLQLU-PUBHSFPPSA-N 50270915 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-4-phenylbutanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL510233 IgG receptor FcRn large subunit p51 Homo sapiens 80000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270915&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935265 104115958 CHEMBL510233 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415634 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)31-54(75(122)104-59(34-49-22-24-51(111)25-23-49)82(129)109-30-11-16-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-12-17-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(33-48-20-18-45(3)19-21-48)101-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)56(32-47-13-8-7-9-14-47)102-74(121)53(15-10-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-9,13-14,18-25,37,43-44,46,52-62,69-70,110-111,132-133H,10-12,15-17,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 GMHAMPACXMVUAV-YLCXNRQGSA-N 50270914 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL504855 IgG receptor FcRn large subunit p51 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270914&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935264 104115957 CHEMBL504855 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415635 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc(C)c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)30-54(75(122)104-59(33-48-21-23-51(111)24-22-48)82(129)109-29-12-19-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-28-13-20-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(34-49-17-10-14-45(3)31-49)101-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)56(32-47-15-8-7-9-16-47)102-74(121)53(18-11-27-92-84(89)90)100-71(118)52(86)25-26-63(87)112/h7-10,14-17,21-24,31,37,43-44,46,52-62,69-70,110-111,132-133H,11-13,18-20,25-30,32-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 VGPJSXNTTDRJGV-YLCXNRQGSA-N 50270913 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(3-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL507649 IgG receptor FcRn large subunit p51 Homo sapiens 4100 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270913&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935263 104115956 CHEMBL507649 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415636 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,66-,67+,72+,73-/m1/s1 UTPJTGHEPBWTPW-PKYKMDOQSA-N 50270894 CHEMBL524722 IgG receptor FcRn large subunit p51 Homo sapiens >250000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270894&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935244 104115937 CHEMBL524722 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415637 C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H122N24O22S2/c1-49(115)73(110-86(133)74(90(2,3)138)111-81(128)60(39-52-21-11-6-12-22-52)105-78(125)57(23-13-33-97-89(94)95)103-75(122)56(91)31-32-68(92)117)85(132)98-44-70(119)102-61(41-54-43-96-48-101-54)80(127)106-59(38-51-19-9-5-10-20-51)79(126)104-58(37-50-17-7-4-8-18-50)76(123)99-45-71(120)112-34-14-24-65(112)83(130)108-63(40-53-27-29-55(116)30-28-53)87(134)114-36-15-25-66(114)84(131)109-64(47-137)82(129)107-62(42-69(93)118)77(124)100-46-72(121)113-35-16-26-67(113)88(135)136/h4-12,17-22,27-30,43,48-49,56-67,73-74,115-116,137-138H,13-16,23-26,31-42,44-47,91H2,1-3H3,(H2,92,117)(H2,93,118)(H,96,101)(H,98,132)(H,99,123)(H,100,124)(H,102,119)(H,103,122)(H,104,126)(H,105,125)(H,106,127)(H,107,129)(H,108,130)(H,109,131)(H,110,133)(H,111,128)(H,135,136)(H4,94,95,97)/t49-,56+,57+,58-,59+,60+,61+,62+,63+,64+,65+,66+,67+,73+,74-/m1/s1 LVFLHSQXNCISLS-ZOJJRNATSA-N 50270893 CHEMBL524476 IgG receptor FcRn large subunit p51 Homo sapiens 39000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270893&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935243 104115936 CHEMBL524476 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415638 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-63(80(127)104-59(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-61(110)79(126)105-60(43-133)78(125)103-58(38-65(89)114)73(120)96-42-68(117)109-31-16-23-62(109)84(131)132)108(7)67(116)41-95-71(118)46(3)98-75(122)55(34-48-17-10-8-11-18-48)102-76(123)57(37-51-39-92-44-97-51)99-66(115)40-94-81(128)69(47(4)111)106-82(129)70(86(5,6)134)107-77(124)56(35-49-19-12-9-13-20-49)101-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,128)(H,95,118)(H,96,120)(H,98,122)(H,99,115)(H,100,119)(H,101,121)(H,102,123)(H,103,125)(H,104,127)(H,105,126)(H,106,129)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1 LNXBOPHNGVFQHY-UODRXTJASA-N 50270892 CHEMBL503489 IgG receptor FcRn large subunit p51 Homo sapiens 3200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270892&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935242 104115935 CHEMBL503489 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415639 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C92H128N24O22S2/c1-50(2)37-69(86(133)110-65(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-67(116)85(132)111-66(48-139)84(131)109-64(43-71(95)120)79(126)102-47-74(123)115-35-18-27-68(115)90(137)138)114(6)73(122)46-101-78(125)60(38-52-19-10-7-11-20-52)106-81(128)61(39-53-21-12-8-13-22-53)108-82(129)63(42-56-44-98-49-103-56)104-72(121)45-100-87(134)75(51(3)117)112-88(135)76(92(4,5)140)113-83(130)62(40-54-23-14-9-15-24-54)107-80(127)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,49-51,58-69,75-76,117-118,139-140H,16-18,25-27,32-43,45-48,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,103)(H,100,134)(H,101,125)(H,102,126)(H,104,121)(H,105,124)(H,106,128)(H,107,127)(H,108,129)(H,109,131)(H,110,133)(H,111,132)(H,112,135)(H,113,130)(H,137,138)(H4,96,97,99)/t51-,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,69+,75+,76-/m1/s1 MVFXXJMBTVTRQG-CQVWQLNPSA-N 50270891 CHEMBL506623 IgG receptor FcRn large subunit p51 Homo sapiens 1300 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270891&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935241 104115934 CHEMBL506623 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415640 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65-,66-,67+,72+,73-/m1/s1 UTPJTGHEPBWTPW-QQIZBGRFSA-N 50270890 CHEMBL524691 IgG receptor FcRn large subunit p51 Homo sapiens 21000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270890&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935240 104115933 CHEMBL524691 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415641 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C92H128N24O22S2/c1-49(2)37-60(81(128)111-66(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-68(116)86(133)112-67(47-139)85(132)110-65(43-71(95)120)78(125)101-46-73(122)115-35-18-27-69(115)90(137)138)106-76(123)50(3)103-80(127)61(38-52-19-10-7-11-20-52)108-82(129)62(39-53-21-12-8-13-22-53)109-83(130)64(42-56-44-98-48-102-56)104-72(121)45-100-87(134)74(51(4)117)113-88(135)75(92(5,6)140)114-84(131)63(40-54-23-14-9-15-24-54)107-79(126)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,48-51,58-69,74-75,117-118,139-140H,16-18,25-27,32-43,45-47,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,102)(H,100,134)(H,101,125)(H,103,127)(H,104,121)(H,105,124)(H,106,123)(H,107,126)(H,108,129)(H,109,130)(H,110,132)(H,111,128)(H,112,133)(H,113,135)(H,114,131)(H,137,138)(H4,96,97,99)/t50-,51-,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,69+,74+,75-/m1/s1 QQLDJXYHCLHAJS-KNFMPVJXSA-N 50270889 CHEMBL525635 IgG receptor FcRn large subunit p51 Homo sapiens 4300 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270889&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935239 104115932 CHEMBL525635 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415642 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69-,70+,71+,76+,77-/m1/s1 WGJHMCNUSNAKEE-AGTNEKHFSA-N 50270888 CHEMBL525201 IgG receptor FcRn large subunit p51 Homo sapiens 5900 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270888&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935238 104115931 CHEMBL525201 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415643 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H126N24O22S2/c1-46(2)35-56(76(123)106-61(38-51-25-27-53(114)28-26-51)85(132)112-34-15-23-64(112)81(128)107-62(44-135)79(126)104-60(40-67(91)116)73(120)97-43-69(118)110-32-16-24-65(110)86(133)134)105-80(127)63-22-14-33-111(63)84(131)47(3)99-75(122)57(36-49-17-9-7-10-18-49)103-77(124)59(39-52-41-94-45-98-52)100-68(117)42-96-82(129)70(48(4)113)108-83(130)71(88(5,6)136)109-78(125)58(37-50-19-11-8-12-20-50)102-74(121)55(21-13-31-95-87(92)93)101-72(119)54(89)29-30-66(90)115/h7-12,17-20,25-28,41,45-48,54-65,70-71,113-114,135-136H,13-16,21-24,29-40,42-44,89H2,1-6H3,(H2,90,115)(H2,91,116)(H,94,98)(H,96,129)(H,97,120)(H,99,122)(H,100,117)(H,101,119)(H,102,121)(H,103,124)(H,104,126)(H,105,127)(H,106,123)(H,107,128)(H,108,130)(H,109,125)(H,133,134)(H4,92,93,95)/t47-,48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,70+,71-/m1/s1 XKKMTYJKVIWWPI-KKCYLYMESA-N 50270887 CHEMBL505622 IgG receptor FcRn large subunit p51 Homo sapiens 3700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270887&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935237 104115930 CHEMBL505622 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415644 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-44(2)33-55(76(123)105-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)80(127)106-61(42-133)79(126)104-59(38-65(89)114)73(120)95-41-67(116)109-31-16-23-63(109)84(131)132)101-71(118)46(4)97-70(117)45(3)98-75(122)56(34-48-17-10-8-11-18-48)103-77(124)58(37-51-39-92-43-96-51)99-66(115)40-94-81(128)68(47(5)111)107-82(129)69(86(6,7)134)108-78(125)57(35-49-19-12-9-13-20-49)102-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,43-47,53-63,68-69,111-112,133-134H,14-16,21-23,28-38,40-42,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,128)(H,95,120)(H,97,117)(H,98,122)(H,99,115)(H,100,119)(H,101,118)(H,102,121)(H,103,124)(H,104,126)(H,105,123)(H,106,127)(H,107,129)(H,108,125)(H,131,132)(H4,90,91,93)/t45-,46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,68+,69-/m1/s1 DXFHHMMOGGSCIW-RSVHAWIGSA-N 50270886 CHEMBL525018 IgG receptor FcRn large subunit p51 Homo sapiens 4500 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270886&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935236 104115929 CHEMBL525018 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415645 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)32-54(75(122)104-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)105-60(42-132)78(125)103-58(37-64(88)113)72(119)95-41-67(116)108-30-15-22-62(108)83(130)131)98-65(114)39-93-70(117)45(3)97-74(121)55(33-47-16-9-7-10-17-47)102-76(123)57(36-50-38-91-43-96-50)99-66(115)40-94-80(127)68(46(4)110)106-81(128)69(85(5,6)133)107-77(124)56(34-48-18-11-8-12-19-48)101-73(120)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,43-46,52-62,68-69,110-111,132-133H,13-15,20-22,27-37,39-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,117)(H,94,127)(H,95,119)(H,97,121)(H,98,114)(H,99,115)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 AURKCJKHUJBTOW-LVOPMODUSA-N 50270885 CHEMBL508377 IgG receptor FcRn large subunit p51 Homo sapiens 4500 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270885&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935235 104115928 CHEMBL508377 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415646 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)32-54(75(122)104-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)105-60(42-132)78(125)103-58(37-64(88)113)73(120)95-41-67(116)108-30-15-22-62(108)83(130)131)100-70(117)45(3)97-65(114)39-93-72(119)55(33-47-16-9-7-10-17-47)101-76(123)57(36-50-38-91-43-96-50)98-66(115)40-94-80(127)68(46(4)110)106-81(128)69(85(5,6)133)107-77(124)56(34-48-18-11-8-12-19-48)102-74(121)53(20-13-29-92-84(89)90)99-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,43-46,52-62,68-69,110-111,132-133H,13-15,20-22,27-37,39-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,119)(H,94,127)(H,95,120)(H,97,114)(H,98,115)(H,99,118)(H,100,117)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 PODDJIVEEGWXML-LVOPMODUSA-N 50270884 CHEMBL506263 IgG receptor FcRn large subunit p51 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270884&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935234 104115927 CHEMBL506263 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415647 CC(C)C[C@H](NC(=O)CNC(=O)C(C)(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-54(73(121)104-59(36-49-24-26-51(112)27-25-49)81(129)110-32-15-22-61(110)78(126)105-60(43-133)76(124)103-58(38-64(89)114)71(119)95-42-67(117)109-31-16-23-62(109)82(130)131)98-66(116)41-96-83(132)85(4,5)108-77(125)56(35-48-19-12-9-13-20-48)102-74(122)57(37-50-39-92-44-97-50)99-65(115)40-94-79(127)68(46(3)111)106-80(128)69(86(6,7)134)107-75(123)55(34-47-17-10-8-11-18-47)101-72(120)53(21-14-30-93-84(90)91)100-70(118)52(87)28-29-63(88)113/h8-13,17-20,24-27,39,44-46,52-62,68-69,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,127)(H,95,119)(H,96,132)(H,98,116)(H,99,115)(H,100,118)(H,101,120)(H,102,122)(H,103,124)(H,104,121)(H,105,126)(H,106,128)(H,107,123)(H,108,125)(H,130,131)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 OOZNCZPFBGELNC-OJSMXDMESA-N 50270883 CHEMBL510473 IgG receptor FcRn large subunit p51 Homo sapiens 17000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270883&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935233 104115926 CHEMBL510473 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415648 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O23S2/c1-48(2)35-59(80(128)110-65(39-53-24-28-56(118)29-25-53)88(136)115-34-13-20-67(115)85(133)111-66(46-139)84(132)109-64(41-70(94)120)78(126)101-45-73(123)114-33-14-21-68(114)89(137)138)103-71(121)43-99-77(125)60(38-52-22-26-55(117)27-23-52)106-81(129)61(36-50-15-8-6-9-16-50)108-82(130)63(40-54-42-97-47-102-54)104-72(122)44-100-86(134)74(49(3)116)112-87(135)75(91(4,5)140)113-83(131)62(37-51-17-10-7-11-18-51)107-79(127)58(19-12-32-98-90(95)96)105-76(124)57(92)30-31-69(93)119/h6-11,15-18,22-29,42,47-49,57-68,74-75,116-118,139-140H,12-14,19-21,30-41,43-46,92H2,1-5H3,(H2,93,119)(H2,94,120)(H,97,102)(H,99,125)(H,100,134)(H,101,126)(H,103,121)(H,104,122)(H,105,124)(H,106,129)(H,107,127)(H,108,130)(H,109,132)(H,110,128)(H,111,133)(H,112,135)(H,113,131)(H,137,138)(H4,95,96,98)/t49-,57+,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 HMXZZVMEIUZBHD-QLQLPVARSA-N 50270882 CHEMBL526187 IgG receptor FcRn large subunit p51 Homo sapiens 3200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270882&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935232 104115925 CHEMBL526187 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415649 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O22S2/c1-49(2)36-59(80(127)110-65(40-54-27-29-56(117)30-28-54)88(135)115-35-16-25-67(115)85(132)111-66(47-138)84(131)109-64(42-70(94)119)78(125)101-46-73(122)114-34-17-26-68(114)89(136)137)103-71(120)44-99-77(124)60(37-51-18-9-6-10-19-51)106-81(128)61(38-52-20-11-7-12-21-52)108-82(129)63(41-55-43-97-48-102-55)104-72(121)45-100-86(133)74(50(3)116)112-87(134)75(91(4,5)139)113-83(130)62(39-53-22-13-8-14-23-53)107-79(126)58(24-15-33-98-90(95)96)105-76(123)57(92)31-32-69(93)118/h6-14,18-23,27-30,43,48-50,57-68,74-75,116-117,138-139H,15-17,24-26,31-42,44-47,92H2,1-5H3,(H2,93,118)(H2,94,119)(H,97,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,126)(H,108,129)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,95,96,98)/t50-,57+,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 MOFZVRUXPRVWJW-XVQGAXIUSA-N 50270850 CHEMBL525014 IgG receptor FcRn large subunit p51 Homo sapiens 2800 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270850&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935231 104115912 CHEMBL525014 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415650 CC[C@H](C)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H128N24O22S2/c1-8-47(4)70(82(129)96-41-67(117)100-56(34-46(2)3)76(123)106-61(37-51-25-27-53(114)28-26-51)85(132)112-33-16-23-63(112)81(128)107-62(44-135)80(127)105-60(39-66(91)116)74(121)98-43-69(119)111-32-17-24-64(111)86(133)134)108-78(125)57(35-49-18-11-9-12-19-49)104-77(124)59(38-52-40-94-45-99-52)101-68(118)42-97-83(130)71(48(5)113)109-84(131)72(88(6,7)136)110-79(126)58(36-50-20-13-10-14-21-50)103-75(122)55(22-15-31-95-87(92)93)102-73(120)54(89)29-30-65(90)115/h9-14,18-21,25-28,40,45-48,54-64,70-72,113-114,135-136H,8,15-17,22-24,29-39,41-44,89H2,1-7H3,(H2,90,115)(H2,91,116)(H,94,99)(H,96,129)(H,97,130)(H,98,121)(H,100,117)(H,101,118)(H,102,120)(H,103,122)(H,104,124)(H,105,127)(H,106,123)(H,107,128)(H,108,125)(H,109,131)(H,110,126)(H,133,134)(H4,92,93,95)/t47-,48+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,70+,71-,72+/m0/s1 GLRIWGCDNHGJTN-FYGOBARVSA-N 50270849 CHEMBL525045 IgG receptor FcRn large subunit p51 Homo sapiens 9400 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270849&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935230 104115911 CHEMBL525045 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415651 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H124N26O22S2/c1-46(2)31-56(77(126)109-62(34-50-22-24-53(116)25-23-50)85(134)114-30-13-20-64(114)82(131)110-63(43-137)81(130)108-61(37-67(91)118)75(124)99-42-70(121)113-29-14-21-65(113)86(135)136)102-68(119)40-97-74(123)59(35-51-38-94-44-100-51)107-78(127)57(32-48-15-8-6-9-16-48)106-79(128)60(36-52-39-95-45-101-52)103-69(120)41-98-83(132)71(47(3)115)111-84(133)72(88(4,5)138)112-80(129)58(33-49-17-10-7-11-18-49)105-76(125)55(19-12-28-96-87(92)93)104-73(122)54(89)26-27-66(90)117/h6-11,15-18,22-25,38-39,44-47,54-65,71-72,115-116,137-138H,12-14,19-21,26-37,40-43,89H2,1-5H3,(H2,90,117)(H2,91,118)(H,94,100)(H,95,101)(H,97,123)(H,98,132)(H,99,124)(H,102,119)(H,103,120)(H,104,122)(H,105,125)(H,106,128)(H,107,127)(H,108,130)(H,109,126)(H,110,131)(H,111,133)(H,112,129)(H,135,136)(H4,92,93,96)/t47-,54+,55+,56+,57+,58+,59-,60+,61+,62+,63+,64+,65+,71+,72-/m1/s1 SEFGHKFHGKGLFZ-SVYDDRGQSA-N 50270848 CHEMBL504493 IgG receptor FcRn large subunit p51 Homo sapiens 3600 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270848&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935229 104115910 CHEMBL504493 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415652 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H129N27O22S2/c1-46(2)34-56(76(127)110-61(37-50-24-26-52(117)27-25-50)84(135)115-33-14-22-63(115)81(132)111-62(44-138)80(131)109-60(39-66(91)119)74(125)101-43-69(122)114-32-15-23-64(114)85(136)137)103-67(120)41-99-73(124)54(20-12-30-97-86(92)93)106-77(128)57(35-48-16-8-6-9-17-48)108-78(129)59(38-51-40-96-45-102-51)104-68(121)42-100-82(133)70(47(3)116)112-83(134)71(88(4,5)139)113-79(130)58(36-49-18-10-7-11-19-49)107-75(126)55(21-13-31-98-87(94)95)105-72(123)53(89)28-29-65(90)118/h6-11,16-19,24-27,40,45-47,53-64,70-71,116-117,138-139H,12-15,20-23,28-39,41-44,89H2,1-5H3,(H2,90,118)(H2,91,119)(H,96,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,126)(H,108,129)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,92,93,97)(H4,94,95,98)/t47-,53+,54-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,70+,71-/m1/s1 KFPQUNOLKHJNOL-VKIHZXIPSA-N 50270847 CHEMBL524856 IgG receptor FcRn large subunit p51 Homo sapiens 4100 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270847&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935228 104115909 CHEMBL524856 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415653 CC(C)C[C@H](NC(=O)CNC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H124N24O22S2/c1-46(2)34-55(75(122)104-60(37-50-24-26-52(113)27-25-50)84(131)111-33-14-22-63(111)80(127)106-61(44-134)78(125)103-58(39-66(90)115)73(120)97-43-69(118)109-31-15-23-64(109)85(132)133)99-67(116)41-95-79(126)62-21-13-32-110(62)83(130)59(36-49-18-10-7-11-19-49)105-76(123)57(38-51-40-93-45-98-51)100-68(117)42-96-81(128)70(47(3)112)107-82(129)71(87(4,5)135)108-77(124)56(35-48-16-8-6-9-17-48)102-74(121)54(20-12-30-94-86(91)92)101-72(119)53(88)28-29-65(89)114/h6-11,16-19,24-27,40,45-47,53-64,70-71,112-113,134-135H,12-15,20-23,28-39,41-44,88H2,1-5H3,(H2,89,114)(H2,90,115)(H,93,98)(H,95,126)(H,96,128)(H,97,120)(H,99,116)(H,100,117)(H,101,119)(H,102,121)(H,103,125)(H,104,122)(H,105,123)(H,106,127)(H,107,129)(H,108,124)(H,132,133)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62-,63+,64+,70+,71-/m1/s1 JUTOVPGZTYTSLV-QTLAHMFMSA-N 50270846 CHEMBL510817 IgG receptor FcRn large subunit p51 Homo sapiens 5000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270846&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935227 104115908 CHEMBL510817 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415654 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H122N24O24S2/c1-44(2)31-53(75(124)105-59(34-48-22-24-50(112)25-23-48)83(132)110-30-13-20-61(110)80(129)106-60(42-135)79(128)103-57(36-64(89)114)72(121)96-41-67(117)109-29-14-21-62(109)84(133)134)98-65(115)39-94-73(122)58(37-68(118)119)104-76(125)54(32-46-15-8-6-9-16-46)102-77(126)56(35-49-38-92-43-97-49)99-66(116)40-95-81(130)69(45(3)111)107-82(131)70(86(4,5)136)108-78(127)55(33-47-17-10-7-11-18-47)101-74(123)52(19-12-28-93-85(90)91)100-71(120)51(87)26-27-63(88)113/h6-11,15-18,22-25,38,43-45,51-62,69-70,111-112,135-136H,12-14,19-21,26-37,39-42,87H2,1-5H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,122)(H,95,130)(H,96,121)(H,98,115)(H,99,116)(H,100,120)(H,101,123)(H,102,126)(H,103,128)(H,104,125)(H,105,124)(H,106,129)(H,107,131)(H,108,127)(H,118,119)(H,133,134)(H4,90,91,93)/t45-,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,61+,62+,69+,70-/m1/s1 GAUDEOLZZHYASR-IDWCDBDKSA-N 50270845 CHEMBL451424 IgG receptor FcRn large subunit p51 Homo sapiens 3100 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270845&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935226 104115907 CHEMBL451424 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415655 CC(C)C[C@H](NC(=O)C(C)(C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-54(74(122)103-59(36-49-24-26-51(112)27-25-49)81(129)110-32-15-22-61(110)78(126)104-60(43-133)77(125)102-58(38-64(89)114)72(120)96-42-67(117)109-31-16-23-62(109)82(130)131)105-83(132)85(4,5)108-66(116)41-94-71(119)55(34-47-17-10-8-11-18-47)100-75(123)57(37-50-39-92-44-97-50)98-65(115)40-95-79(127)68(46(3)111)106-80(128)69(86(6,7)134)107-76(124)56(35-48-19-12-9-13-20-48)101-73(121)53(21-14-30-93-84(90)91)99-70(118)52(87)28-29-63(88)113/h8-13,17-20,24-27,39,44-46,52-62,68-69,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,132)(H,106,128)(H,107,124)(H,108,116)(H,130,131)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 IBXUOXAWRBNUSK-OJSMXDMESA-N 50270844 CHEMBL504266 IgG receptor FcRn large subunit p51 Homo sapiens 2400 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270844&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935225 104115906 CHEMBL504266 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415656 CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O23S2/c1-48(2)35-59(80(128)110-65(39-53-24-28-56(118)29-25-53)88(136)115-34-13-20-67(115)85(133)111-66(46-139)84(132)109-64(41-70(94)120)78(126)101-45-73(123)114-33-14-21-68(114)89(137)138)106-81(129)61(38-52-22-26-55(117)27-23-52)103-71(121)43-99-77(125)60(36-50-15-8-6-9-16-50)107-82(130)63(40-54-42-97-47-102-54)104-72(122)44-100-86(134)74(49(3)116)112-87(135)75(91(4,5)140)113-83(131)62(37-51-17-10-7-11-18-51)108-79(127)58(19-12-32-98-90(95)96)105-76(124)57(92)30-31-69(93)119/h6-11,15-18,22-29,42,47-49,57-68,74-75,116-118,139-140H,12-14,19-21,30-41,43-46,92H2,1-5H3,(H2,93,119)(H2,94,120)(H,97,102)(H,99,125)(H,100,134)(H,101,126)(H,103,121)(H,104,122)(H,105,124)(H,106,129)(H,107,130)(H,108,127)(H,109,132)(H,110,128)(H,111,133)(H,112,135)(H,113,131)(H,137,138)(H4,95,96,98)/t49-,57+,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 FHNANAOGEJSYFI-HQWAHVIOSA-N 50270843 CHEMBL524908 IgG receptor FcRn large subunit p51 Homo sapiens 13000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270843&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935224 104115905 CHEMBL524908 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415657 CC(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C91H126N24O22S2/c1-49(2)36-59(80(127)110-65(40-54-27-29-56(117)30-28-54)88(135)115-35-16-25-67(115)85(132)111-66(47-138)84(131)109-64(42-70(94)119)78(125)101-46-73(122)114-34-17-26-68(114)89(136)137)106-81(128)61(38-52-20-11-7-12-21-52)103-71(120)44-99-77(124)60(37-51-18-9-6-10-19-51)107-82(129)63(41-55-43-97-48-102-55)104-72(121)45-100-86(133)74(50(3)116)112-87(134)75(91(4,5)139)113-83(130)62(39-53-22-13-8-14-23-53)108-79(126)58(24-15-33-98-90(95)96)105-76(123)57(92)31-32-69(93)118/h6-14,18-23,27-30,43,48-50,57-68,74-75,116-117,138-139H,15-17,24-26,31-42,44-47,92H2,1-5H3,(H2,93,118)(H2,94,119)(H,97,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,128)(H,107,129)(H,108,126)(H,109,131)(H,110,127)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,95,96,98)/t50-,57+,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,74+,75-/m1/s1 ZPJFDXPMNYPTKD-DJTHZEPZSA-N 50270842 CHEMBL508983 IgG receptor FcRn large subunit p51 Homo sapiens 13000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270842&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935223 104115904 CHEMBL508983 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415658 CC[C@H](C)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H128N24O22S2/c1-8-47(4)70(83(130)105-56(34-46(2)3)77(124)106-61(37-51-25-27-53(114)28-26-51)85(132)112-33-16-23-63(112)81(128)107-62(44-135)80(127)104-60(39-66(91)116)75(122)98-43-69(119)111-32-17-24-64(111)86(133)134)108-68(118)42-96-74(121)57(35-49-18-11-9-12-19-49)102-78(125)59(38-52-40-94-45-99-52)100-67(117)41-97-82(129)71(48(5)113)109-84(131)72(88(6,7)136)110-79(126)58(36-50-20-13-10-14-21-50)103-76(123)55(22-15-31-95-87(92)93)101-73(120)54(89)29-30-65(90)115/h9-14,18-21,25-28,40,45-48,54-64,70-72,113-114,135-136H,8,15-17,22-24,29-39,41-44,89H2,1-7H3,(H2,90,115)(H2,91,116)(H,94,99)(H,96,121)(H,97,129)(H,98,122)(H,100,117)(H,101,120)(H,102,125)(H,103,123)(H,104,127)(H,105,130)(H,106,124)(H,107,128)(H,108,118)(H,109,131)(H,110,126)(H,133,134)(H4,92,93,95)/t47-,48+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,70+,71-,72+/m0/s1 UENMCFLPLIZIGA-FYGOBARVSA-N 50270841 CHEMBL454229 IgG receptor FcRn large subunit p51 Homo sapiens 18000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270841&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935222 104115903 CHEMBL454229 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415659 CC(C)C[C@H](NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H124N26O22S2/c1-46(2)31-56(77(126)109-62(34-50-22-24-53(116)25-23-50)85(134)114-30-13-20-64(114)82(131)110-63(43-137)81(130)108-61(37-67(91)118)75(124)99-42-70(121)113-29-14-21-65(113)86(135)136)105-78(127)59(35-51-38-94-44-100-51)102-68(119)40-97-74(123)57(32-48-15-8-6-9-16-48)106-79(128)60(36-52-39-95-45-101-52)103-69(120)41-98-83(132)71(47(3)115)111-84(133)72(88(4,5)138)112-80(129)58(33-49-17-10-7-11-18-49)107-76(125)55(19-12-28-96-87(92)93)104-73(122)54(89)26-27-66(90)117/h6-11,15-18,22-25,38-39,44-47,54-65,71-72,115-116,137-138H,12-14,19-21,26-37,40-43,89H2,1-5H3,(H2,90,117)(H2,91,118)(H,94,100)(H,95,101)(H,97,123)(H,98,132)(H,99,124)(H,102,119)(H,103,120)(H,104,122)(H,105,127)(H,106,128)(H,107,125)(H,108,130)(H,109,126)(H,110,131)(H,111,133)(H,112,129)(H,135,136)(H4,92,93,96)/t47-,54+,55+,56+,57+,58+,59-,60+,61+,62+,63+,64+,65+,71+,72-/m1/s1 XXVWNYAYRJSQGC-SVYDDRGQSA-N 50270840 CHEMBL525040 IgG receptor FcRn large subunit p51 Homo sapiens 12000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270840&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935221 104115902 CHEMBL525040 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415660 CC(C)C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H129N27O22S2/c1-46(2)34-56(77(128)110-61(37-50-24-26-52(117)27-25-50)84(135)115-33-14-22-63(115)81(132)111-62(44-138)80(131)109-60(39-66(91)119)74(125)101-43-69(122)114-32-15-23-64(114)85(136)137)106-75(126)54(20-12-30-97-86(92)93)103-67(120)41-99-73(124)57(35-48-16-8-6-9-17-48)107-78(129)59(38-51-40-96-45-102-51)104-68(121)42-100-82(133)70(47(3)116)112-83(134)71(88(4,5)139)113-79(130)58(36-49-18-10-7-11-19-49)108-76(127)55(21-13-31-98-87(94)95)105-72(123)53(89)28-29-65(90)118/h6-11,16-19,24-27,40,45-47,53-64,70-71,116-117,138-139H,12-15,20-23,28-39,41-44,89H2,1-5H3,(H2,90,118)(H2,91,119)(H,96,102)(H,99,124)(H,100,133)(H,101,125)(H,103,120)(H,104,121)(H,105,123)(H,106,126)(H,107,129)(H,108,127)(H,109,131)(H,110,128)(H,111,132)(H,112,134)(H,113,130)(H,136,137)(H4,92,93,97)(H4,94,95,98)/t47-,53+,54-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,70+,71-/m1/s1 CMCHQCYGHXEPCM-VKIHZXIPSA-N 50270839 CHEMBL505790 IgG receptor FcRn large subunit p51 Homo sapiens 8100 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270839&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935220 104115901 CHEMBL505790 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415661 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60-,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-PNQCIWQISA-N 50270903 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2R)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524487 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270903&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935253 104115946 CHEMBL524487 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415662 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58-,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-CFVPATMLSA-N 50270902 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2R)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL446301 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270902&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935252 104115945 CHEMBL446301 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415663 CC(C)C[C@@H](NC(=O)CNC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53-,54-,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-OARSYXCYSA-N 50270901 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2R)-2-(2-{2-[(2R)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501492 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270901&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935251 104115944 CHEMBL501492 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415664 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54-,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-FSUBTDEOSA-N 50270900 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2R)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503695 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270900&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935250 104115943 CHEMBL503695 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415665 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68-,69+/m1/s1 XMBRKVYGPTUTDQ-REHCMJGESA-N 50270899 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2R,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506091 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270899&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935249 104115942 CHEMBL506091 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415666 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55-,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-JXHPJOSXSA-N 50270898 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506646 IgG receptor FcRn large subunit p51 Homo sapiens 1800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270898&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935248 104115941 CHEMBL506646 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415667 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52-,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-GXYFPZCESA-N 50270897 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501541 IgG receptor FcRn large subunit p51 Homo sapiens 280 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270897&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935247 104115940 CHEMBL501541 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415668 CC(C)C[C@H](NC(=O)CN(C)C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-55(75(122)104-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)79(126)105-61(43-133)78(125)103-59(38-65(89)114)72(119)95-41-68(117)109-31-16-23-63(109)84(131)132)99-67(116)42-108(7)82(129)46(3)97-74(121)56(34-48-17-10-8-11-18-48)102-76(123)58(37-51-39-92-44-96-51)98-66(115)40-94-80(127)69(47(4)111)106-81(128)70(86(5,6)134)107-77(124)57(35-49-19-12-9-13-20-49)101-73(120)54(21-14-30-93-85(90)91)100-71(118)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,127)(H,95,119)(H,97,121)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1 WVVLRGIVQCLOAZ-UODRXTJASA-N 50270896 CHEMBL525636 IgG receptor FcRn large subunit p51 Homo sapiens 190 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270896&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935246 104115939 CHEMBL525636 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415669 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69+,70+,71+,76+,77-/m1/s1 WGJHMCNUSNAKEE-RRTVRWFKSA-N 50270895 CHEMBL526337 IgG receptor FcRn large subunit p51 Homo sapiens 3800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270895&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935245 104115938 CHEMBL526337 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415670 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,66-,67+,72+,73-/m1/s1 UTPJTGHEPBWTPW-PKYKMDOQSA-N 50270894 CHEMBL524722 IgG receptor FcRn large subunit p51 Homo sapiens >100000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270894&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935244 104115937 CHEMBL524722 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415671 C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H122N24O22S2/c1-49(115)73(110-86(133)74(90(2,3)138)111-81(128)60(39-52-21-11-6-12-22-52)105-78(125)57(23-13-33-97-89(94)95)103-75(122)56(91)31-32-68(92)117)85(132)98-44-70(119)102-61(41-54-43-96-48-101-54)80(127)106-59(38-51-19-9-5-10-20-51)79(126)104-58(37-50-17-7-4-8-18-50)76(123)99-45-71(120)112-34-14-24-65(112)83(130)108-63(40-53-27-29-55(116)30-28-53)87(134)114-36-15-25-66(114)84(131)109-64(47-137)82(129)107-62(42-69(93)118)77(124)100-46-72(121)113-35-16-26-67(113)88(135)136/h4-12,17-22,27-30,43,48-49,56-67,73-74,115-116,137-138H,13-16,23-26,31-42,44-47,91H2,1-3H3,(H2,92,117)(H2,93,118)(H,96,101)(H,98,132)(H,99,123)(H,100,124)(H,102,119)(H,103,122)(H,104,126)(H,105,125)(H,106,127)(H,107,129)(H,108,130)(H,109,131)(H,110,133)(H,111,128)(H,135,136)(H4,94,95,97)/t49-,56+,57+,58-,59+,60+,61+,62+,63+,64+,65+,66+,67+,73+,74-/m1/s1 LVFLHSQXNCISLS-ZOJJRNATSA-N 50270893 CHEMBL524476 IgG receptor FcRn large subunit p51 Homo sapiens 18300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270893&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935243 104115936 CHEMBL524476 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415672 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)31-54(75(122)104-59(33-48-22-24-51(111)25-23-48)82(129)109-30-13-20-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-14-21-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)56(34-49-18-11-10-15-45(49)3)102-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)55(32-47-16-8-7-9-17-47)101-74(121)53(19-12-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-11,15-18,22-25,37,43-44,46,52-62,69-70,110-111,132-133H,12-14,19-21,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,121)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 FOVBJJGWGDWTDE-YLCXNRQGSA-N 50270912 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(2-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL509409 IgG receptor FcRn large subunit p51 Homo sapiens 1000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270912&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935262 104115955 CHEMBL509409 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415673 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H122N24O22S2/c1-46(2)32-57(78(125)107-62(35-49-22-25-54(114)26-23-49)85(132)112-31-12-19-64(112)82(129)108-63(44-135)81(128)106-61(38-67(91)116)76(123)99-43-71(120)111-30-13-20-65(111)86(133)134)101-69(118)41-96-68(117)40-97-75(122)58(36-50-21-24-51-16-9-10-17-52(51)33-50)104-79(126)60(37-53-39-94-45-100-53)102-70(119)42-98-83(130)72(47(3)113)109-84(131)73(88(4,5)136)110-80(127)59(34-48-14-7-6-8-15-48)105-77(124)56(18-11-29-95-87(92)93)103-74(121)55(89)27-28-66(90)115/h6-10,14-17,21-26,33,39,45-47,55-65,72-73,113-114,135-136H,11-13,18-20,27-32,34-38,40-44,89H2,1-5H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,122)(H,98,130)(H,99,123)(H,101,118)(H,102,119)(H,103,121)(H,104,126)(H,105,124)(H,106,128)(H,107,125)(H,108,129)(H,109,131)(H,110,127)(H,133,134)(H4,92,93,95)/t47-,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,72+,73+/m1/s1 WQMRXUZTNLLGCS-LHPJQMSHSA-N 50270911 CHEMBL501031 IgG receptor FcRn large subunit p51 Homo sapiens 90000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270911&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935261 104115954 CHEMBL501031 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415674 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H122N24O22S2/c1-46(2)33-57(78(125)107-62(35-49-24-26-53(114)27-25-49)85(132)112-32-13-22-64(112)82(129)108-63(44-135)81(128)106-61(38-67(91)116)76(123)99-43-71(120)111-31-14-23-65(111)86(133)134)101-69(118)41-96-68(117)40-97-75(122)59(36-51-19-11-18-50-17-9-10-20-54(50)51)105-79(126)60(37-52-39-94-45-100-52)102-70(119)42-98-83(130)72(47(3)113)109-84(131)73(88(4,5)136)110-80(127)58(34-48-15-7-6-8-16-48)104-77(124)56(21-12-30-95-87(92)93)103-74(121)55(89)28-29-66(90)115/h6-11,15-20,24-27,39,45-47,55-65,72-73,113-114,135-136H,12-14,21-23,28-38,40-44,89H2,1-5H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,122)(H,98,130)(H,99,123)(H,101,118)(H,102,119)(H,103,121)(H,104,124)(H,105,126)(H,106,128)(H,107,125)(H,108,129)(H,109,131)(H,110,127)(H,133,134)(H4,92,93,95)/t47-,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,72+,73+/m1/s1 VRIWDRAXOYSVID-LHPJQMSHSA-N 50270910 CHEMBL505501 IgG receptor FcRn large subunit p51 Homo sapiens 13000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270910&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935260 104115953 CHEMBL505501 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415675 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24S2/c1-43(2)30-53(74(122)103-58(33-47-19-23-50(111)24-20-47)81(129)108-29-10-15-60(108)78(126)104-59(41-134)77(125)102-57(35-63(87)113)72(120)95-40-67(117)107-28-11-16-61(107)82(130)131)97-65(115)38-92-64(114)37-93-71(119)54(32-46-17-21-49(22-18-46)109(132)133)100-75(123)56(34-48-36-90-42-96-48)98-66(116)39-94-79(127)68(44(3)110)105-80(128)69(84(4,5)135)106-76(124)55(31-45-12-7-6-8-13-45)101-73(121)52(14-9-27-91-83(88)89)99-70(118)51(85)25-26-62(86)112/h6-8,12-13,17-24,36,42-44,51-61,68-69,110-111,134-135H,9-11,14-16,25-35,37-41,85H2,1-5H3,(H2,86,112)(H2,87,113)(H,90,96)(H,92,114)(H,93,119)(H,94,127)(H,95,120)(H,97,115)(H,98,116)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,128)(H,106,124)(H,130,131)(H4,88,89,91)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 VOFXLGXZLUJZHN-FSOLOWAYSA-N 50270909 CHEMBL502045 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270909&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935259 104115952 CHEMBL502045 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415676 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccnc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O22S2/c1-43(2)29-52(73(121)103-57(31-46-19-21-49(110)22-20-46)80(128)108-28-11-17-59(108)77(125)104-58(41-131)76(124)102-56(34-62(86)112)71(119)95-40-66(116)107-27-12-18-60(107)81(129)130)97-64(114)38-92-63(113)37-93-70(118)53(32-47-15-9-25-89-35-47)100-74(122)55(33-48-36-90-42-96-48)98-65(115)39-94-78(126)67(44(3)109)105-79(127)68(83(4,5)132)106-75(123)54(30-45-13-7-6-8-14-45)101-72(120)51(16-10-26-91-82(87)88)99-69(117)50(84)23-24-61(85)111/h6-9,13-15,19-22,25,35-36,42-44,50-60,67-68,109-110,131-132H,10-12,16-18,23-24,26-34,37-41,84H2,1-5H3,(H2,85,111)(H2,86,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,87,88,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,67+,68+/m1/s1 RRDRVDPPAULRFT-ZHJKNKPASA-N 50270908 CHEMBL505603 IgG receptor FcRn large subunit p51 Homo sapiens 60000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270908&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935258 104115951 CHEMBL505603 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415677 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccn1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O22S2/c1-43(2)30-52(73(121)103-57(32-46-20-22-49(110)23-21-46)80(128)108-29-12-18-59(108)77(125)104-58(41-131)76(124)102-56(35-62(86)112)71(119)95-40-66(116)107-28-13-19-60(107)81(129)130)97-64(114)38-92-63(113)37-93-70(118)54(33-47-16-9-10-26-90-47)101-74(122)55(34-48-36-89-42-96-48)98-65(115)39-94-78(126)67(44(3)109)105-79(127)68(83(4,5)132)106-75(123)53(31-45-14-7-6-8-15-45)100-72(120)51(17-11-27-91-82(87)88)99-69(117)50(84)24-25-61(85)111/h6-10,14-16,20-23,26,36,42-44,50-60,67-68,109-110,131-132H,11-13,17-19,24-25,27-35,37-41,84H2,1-5H3,(H2,85,111)(H2,86,112)(H,89,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,120)(H,101,122)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,87,88,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,67+,68+/m1/s1 RSINYEGNQRXSBV-ZHJKNKPASA-N 50270907 CHEMBL526336 IgG receptor FcRn large subunit p51 Homo sapiens 90000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270907&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935257 104115950 CHEMBL526336 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415678 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H115F5N24O22S2/c1-39(2)26-48(74(126)108-53(28-42-17-19-44(115)20-18-42)81(133)113-25-10-15-55(113)78(130)109-54(37-136)77(129)107-52(31-58(92)117)72(124)100-36-62(121)112-24-11-16-56(112)82(134)135)102-60(119)34-97-59(118)33-98-71(123)51(30-45-63(85)65(87)67(89)66(88)64(45)86)106-75(127)50(29-43-32-95-38-101-43)103-61(120)35-99-79(131)68(40(3)114)110-80(132)69(84(4,5)137)111-76(128)49(27-41-12-7-6-8-13-41)105-73(125)47(14-9-23-96-83(93)94)104-70(122)46(90)21-22-57(91)116/h6-8,12-13,17-20,32,38-40,46-56,68-69,114-115,136-137H,9-11,14-16,21-31,33-37,90H2,1-5H3,(H2,91,116)(H2,92,117)(H,95,101)(H,97,118)(H,98,123)(H,99,131)(H,100,124)(H,102,119)(H,103,120)(H,104,122)(H,105,125)(H,106,127)(H,107,129)(H,108,126)(H,109,130)(H,110,132)(H,111,128)(H,134,135)(H4,93,94,96)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54-,55+,56+,68+,69+/m1/s1 FZFPNCVNLIHAHI-APCXSTTPSA-N 50270906 CHEMBL524517 IgG receptor FcRn large subunit p51 Homo sapiens 120000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270906&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935256 104115949 CHEMBL524517 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415679 COc1ccc(C[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N2CCC[C@H]2C(O)=O)cc1 InChI=1S/C85H122N24O23S2/c1-44(2)31-54(75(122)104-59(34-47-18-22-50(111)23-19-47)82(129)109-30-11-16-61(109)79(126)105-60(42-133)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-12-17-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(33-48-20-24-51(132-6)25-21-48)101-76(123)57(35-49-37-91-43-97-49)99-67(116)40-95-80(127)69(45(3)110)106-81(128)70(85(4,5)134)107-77(124)56(32-46-13-8-7-9-14-46)102-74(121)53(15-10-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-9,13-14,18-25,37,43-45,52-62,69-70,110-111,133-134H,10-12,15-17,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 BXTLWSSWVCMERS-QVSLJBRWSA-N 50270905 CHEMBL506836 IgG receptor FcRn large subunit p51 Homo sapiens 100000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270905&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935255 104115948 CHEMBL506836 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415680 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H121N25O22S2/c1-43(2)30-53(74(122)104-58(33-47-19-23-50(111)24-20-47)81(129)109-29-10-15-60(109)78(126)105-59(41-132)77(125)103-57(35-63(88)113)72(120)96-40-67(117)108-28-11-16-61(108)82(130)131)98-65(115)38-93-64(114)37-94-71(119)54(32-46-17-21-48(85)22-18-46)101-75(123)56(34-49-36-91-42-97-49)99-66(116)39-95-79(127)68(44(3)110)106-80(128)69(84(4,5)133)107-76(124)55(31-45-12-7-6-8-13-45)102-73(121)52(14-9-27-92-83(89)90)100-70(118)51(86)25-26-62(87)112/h6-8,12-13,17-24,36,42-44,51-61,68-69,110-111,132-133H,9-11,14-16,25-35,37-41,85-86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 CBEDAKGJOZPSSM-FSOLOWAYSA-N 50270904 CHEMBL509666 IgG receptor FcRn large subunit p51 Homo sapiens 13000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270904&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935254 104115947 CHEMBL509666 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415681 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H120N24O22S2/c1-44(2)30-54(74(121)103-57(32-47-21-23-51(111)24-22-47)81(128)108-29-12-19-60(108)78(125)104-59(42-132)76(123)102-56(35-64(88)113)72(119)96-40-68(117)107-28-13-20-61(107)83(130)131)98-66(115)38-93-65(114)37-94-77(124)62-33-48-16-9-10-17-49(48)41-109(62)82(129)58(34-50-36-91-43-97-50)99-67(116)39-95-79(126)69(45(3)110)105-80(127)70(85(4,5)133)106-75(122)55(31-46-14-7-6-8-15-46)101-73(120)53(18-11-27-92-84(89)90)100-71(118)52(86)25-26-63(87)112/h6-10,14-17,21-24,36,43-45,52-62,69-70,110-111,132-133H,11-13,18-20,25-35,37-42,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,124)(H,95,126)(H,96,119)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,121)(H,104,125)(H,105,127)(H,106,122)(H,130,131)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70+/m1/s1 RRTFOICYEPNINN-UXGAPGMISA-N 50270921 CHEMBL498892 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270921&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935270 104115964 CHEMBL498892 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415682 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)31-52(72(119)101-56(33-46-22-24-49(109)25-23-46)80(127)107-30-13-20-58(107)76(123)102-57(41-130)75(122)100-55(35-61(86)111)70(117)94-40-65(115)106-29-14-21-59(106)81(128)129)96-63(113)38-91-62(112)37-92-78(125)67(47-17-10-7-11-18-47)104-73(120)54(34-48-36-89-42-95-48)97-64(114)39-93-77(124)66(44(3)108)103-79(126)68(83(4,5)131)105-74(121)53(32-45-15-8-6-9-16-45)99-71(118)51(19-12-28-90-82(87)88)98-69(116)50(84)26-27-60(85)110/h6-11,15-18,22-25,36,42-44,50-59,66-68,108-109,130-131H,12-14,19-21,26-35,37-41,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,89,95)(H,91,112)(H,92,125)(H,93,124)(H,94,117)(H,96,113)(H,97,114)(H,98,116)(H,99,118)(H,100,122)(H,101,119)(H,102,123)(H,103,126)(H,104,120)(H,105,121)(H,128,129)(H4,87,88,90)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,66+,67+,68-/m1/s1 FSFORDRZUSZFNV-VFPQSOOHSA-N 50270920 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-2-phenylacetamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524692 IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270920&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935269 104115963 CHEMBL524692 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415683 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H121N25O22S2/c1-44(2)30-55(76(124)106-60(32-47-21-23-50(113)24-22-47)83(131)111-29-12-19-62(111)80(128)107-61(42-134)79(127)105-59(35-65(89)115)74(122)98-41-69(119)110-28-13-20-63(110)84(132)133)100-67(117)39-95-66(116)38-96-73(121)57(33-48-36-94-53-17-10-9-16-51(48)53)104-77(125)58(34-49-37-92-43-99-49)101-68(118)40-97-81(129)70(45(3)112)108-82(130)71(86(4,5)135)109-78(126)56(31-46-14-7-6-8-15-46)103-75(123)54(18-11-27-93-85(90)91)102-72(120)52(87)25-26-64(88)114/h6-10,14-17,21-24,36-37,43-45,52,54-63,70-71,94,112-113,134-135H,11-13,18-20,25-35,38-42,87H2,1-5H3,(H2,88,114)(H2,89,115)(H,92,99)(H,95,116)(H,96,121)(H,97,129)(H,98,122)(H,100,117)(H,101,118)(H,102,120)(H,103,123)(H,104,125)(H,105,127)(H,106,124)(H,107,128)(H,108,130)(H,109,126)(H,132,133)(H4,90,91,93)/t45-,52+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 YCGCFCPNCZJFMK-SQDIJLIXSA-N 50270919 CHEMBL527084 IgG receptor FcRn large subunit p51 Homo sapiens 2700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270919&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935268 104115962 CHEMBL527084 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415684 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O23S2/c1-44(2)31-55(76(125)106-60(34-49-20-24-52(114)25-21-49)83(132)111-30-11-16-62(111)80(129)107-61(42-135)79(128)105-59(36-65(89)116)74(123)97-41-69(120)110-29-12-17-63(110)84(133)134)100-67(118)39-94-66(117)38-95-73(122)56(33-48-18-22-50(23-19-48)99-46(4)113)103-77(126)58(35-51-37-92-43-98-51)101-68(119)40-96-81(130)70(45(3)112)108-82(131)71(86(5,6)136)109-78(127)57(32-47-13-8-7-9-14-47)104-75(124)54(15-10-28-93-85(90)91)102-72(121)53(87)26-27-64(88)115/h7-9,13-14,18-25,37,43-45,53-63,70-71,112,114,135-136H,10-12,15-17,26-36,38-42,87H2,1-6H3,(H2,88,115)(H2,89,116)(H,92,98)(H,94,117)(H,95,122)(H,96,130)(H,97,123)(H,99,113)(H,100,118)(H,101,119)(H,102,121)(H,103,126)(H,104,124)(H,105,128)(H,106,125)(H,107,129)(H,108,131)(H,109,127)(H,133,134)(H4,90,91,93)/t45-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 JPKQWCGCSKXPJW-CJDQEJCYSA-N 50270918 CHEMBL444687 IgG receptor FcRn large subunit p51 Homo sapiens 270000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270918&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935267 104115961 CHEMBL444687 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415685 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H126N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h7,10-11,17-18,22-25,37,43-46,51-61,68-69,109-110,131-132H,6,8-9,12-16,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 SMJLMHPTWAXYSF-JFFCSCEESA-N 50270917 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-cyclohexylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL527080 IgG receptor FcRn large subunit p51 Homo sapiens 4500 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270917&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935266 104115960 CHEMBL527080 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415686 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-45(2)33-55(75(122)104-59(35-49-22-25-51(111)26-23-49)82(129)109-32-13-20-61(109)79(126)105-60(43-132)78(125)103-58(37-64(88)113)73(120)96-42-68(117)108-31-14-21-62(108)83(130)131)98-66(115)40-93-65(114)39-94-72(119)54(28-24-47-15-8-6-9-16-47)101-76(123)57(36-50-38-91-44-97-50)99-67(116)41-95-80(127)69(46(3)110)106-81(128)70(85(4,5)133)107-77(124)56(34-48-17-10-7-11-18-48)102-74(121)53(19-12-30-92-84(89)90)100-71(118)52(86)27-29-63(87)112/h6-11,15-18,22-23,25-26,38,44-46,52-62,69-70,110-111,132-133H,12-14,19-21,24,27-37,39-43,86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 NTNKRJXQUHLQLU-PUBHSFPPSA-N 50270915 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-4-phenylbutanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL510233 IgG receptor FcRn large subunit p51 Homo sapiens 7800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270915&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935265 104115958 CHEMBL510233 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415687 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)31-54(75(122)104-59(34-49-22-24-51(111)25-23-49)82(129)109-30-11-16-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-12-17-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(33-48-20-18-45(3)19-21-48)101-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)56(32-47-13-8-7-9-14-47)102-74(121)53(15-10-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-9,13-14,18-25,37,43-44,46,52-62,69-70,110-111,132-133H,10-12,15-17,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 GMHAMPACXMVUAV-YLCXNRQGSA-N 50270914 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL504855 IgG receptor FcRn large subunit p51 Homo sapiens 200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270914&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935264 104115957 CHEMBL504855 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415688 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc(C)c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)30-54(75(122)104-59(33-48-21-23-51(111)24-22-48)82(129)109-29-12-19-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-28-13-20-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(34-49-17-10-14-45(3)31-49)101-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)56(32-47-15-8-7-9-16-47)102-74(121)53(18-11-27-92-84(89)90)100-71(118)52(86)25-26-63(87)112/h7-10,14-17,21-24,31,37,43-44,46,52-62,69-70,110-111,132-133H,11-13,18-20,25-30,32-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 VGPJSXNTTDRJGV-YLCXNRQGSA-N 50270913 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(3-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL507649 IgG receptor FcRn large subunit p51 Homo sapiens 670 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270913&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935263 104115956 CHEMBL507649 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415689 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)31-54(75(122)104-59(33-48-22-24-51(111)25-23-48)82(129)109-30-13-20-61(109)79(126)105-60(42-132)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-14-21-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)56(34-49-18-11-10-15-45(49)3)102-76(123)57(35-50-37-91-43-97-50)99-67(116)40-95-80(127)69(46(4)110)106-81(128)70(85(5,6)133)107-77(124)55(32-47-16-8-7-9-17-47)101-74(121)53(19-12-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-11,15-18,22-25,37,43-44,46,52-62,69-70,110-111,132-133H,12-14,19-21,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,121)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 FOVBJJGWGDWTDE-YLCXNRQGSA-N 50270912 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(2-methylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic::CHEMBL509409 IgG receptor FcRn large subunit p51 Homo sapiens 200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270912&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935262 104115955 CHEMBL509409 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415690 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H122N24O22S2/c1-46(2)32-57(78(125)107-62(35-49-22-25-54(114)26-23-49)85(132)112-31-12-19-64(112)82(129)108-63(44-135)81(128)106-61(38-67(91)116)76(123)99-43-71(120)111-30-13-20-65(111)86(133)134)101-69(118)41-96-68(117)40-97-75(122)58(36-50-21-24-51-16-9-10-17-52(51)33-50)104-79(126)60(37-53-39-94-45-100-53)102-70(119)42-98-83(130)72(47(3)113)109-84(131)73(88(4,5)136)110-80(127)59(34-48-14-7-6-8-15-48)105-77(124)56(18-11-29-95-87(92)93)103-74(121)55(89)27-28-66(90)115/h6-10,14-17,21-26,33,39,45-47,55-65,72-73,113-114,135-136H,11-13,18-20,27-32,34-38,40-44,89H2,1-5H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,122)(H,98,130)(H,99,123)(H,101,118)(H,102,119)(H,103,121)(H,104,126)(H,105,124)(H,106,128)(H,107,125)(H,108,129)(H,109,131)(H,110,127)(H,133,134)(H4,92,93,95)/t47-,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,72+,73+/m1/s1 WQMRXUZTNLLGCS-LHPJQMSHSA-N 50270911 CHEMBL501031 IgG receptor FcRn large subunit p51 Homo sapiens 11000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270911&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935261 104115954 CHEMBL501031 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415691 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H122N24O22S2/c1-46(2)33-57(78(125)107-62(35-49-24-26-53(114)27-25-49)85(132)112-32-13-22-64(112)82(129)108-63(44-135)81(128)106-61(38-67(91)116)76(123)99-43-71(120)111-31-14-23-65(111)86(133)134)101-69(118)41-96-68(117)40-97-75(122)59(36-51-19-11-18-50-17-9-10-20-54(50)51)105-79(126)60(37-52-39-94-45-100-52)102-70(119)42-98-83(130)72(47(3)113)109-84(131)73(88(4,5)136)110-80(127)58(34-48-15-7-6-8-16-48)104-77(124)56(21-12-30-95-87(92)93)103-74(121)55(89)28-29-66(90)115/h6-11,15-20,24-27,39,45-47,55-65,72-73,113-114,135-136H,12-14,21-23,28-38,40-44,89H2,1-5H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,122)(H,98,130)(H,99,123)(H,101,118)(H,102,119)(H,103,121)(H,104,124)(H,105,126)(H,106,128)(H,107,125)(H,108,129)(H,109,131)(H,110,127)(H,133,134)(H4,92,93,95)/t47-,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,72+,73+/m1/s1 VRIWDRAXOYSVID-LHPJQMSHSA-N 50270910 CHEMBL505501 IgG receptor FcRn large subunit p51 Homo sapiens 2200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270910&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935260 104115953 CHEMBL505501 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415692 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24S2/c1-43(2)30-53(74(122)103-58(33-47-19-23-50(111)24-20-47)81(129)108-29-10-15-60(108)78(126)104-59(41-134)77(125)102-57(35-63(87)113)72(120)95-40-67(117)107-28-11-16-61(107)82(130)131)97-65(115)38-92-64(114)37-93-71(119)54(32-46-17-21-49(22-18-46)109(132)133)100-75(123)56(34-48-36-90-42-96-48)98-66(116)39-94-79(127)68(44(3)110)105-80(128)69(84(4,5)135)106-76(124)55(31-45-12-7-6-8-13-45)101-73(121)52(14-9-27-91-83(88)89)99-70(118)51(85)25-26-62(86)112/h6-8,12-13,17-24,36,42-44,51-61,68-69,110-111,134-135H,9-11,14-16,25-35,37-41,85H2,1-5H3,(H2,86,112)(H2,87,113)(H,90,96)(H,92,114)(H,93,119)(H,94,127)(H,95,120)(H,97,115)(H,98,116)(H,99,118)(H,100,123)(H,101,121)(H,102,125)(H,103,122)(H,104,126)(H,105,128)(H,106,124)(H,130,131)(H4,88,89,91)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 VOFXLGXZLUJZHN-FSOLOWAYSA-N 50270909 CHEMBL502045 IgG receptor FcRn large subunit p51 Homo sapiens 84000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270909&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935259 104115952 CHEMBL502045 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415693 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccnc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O22S2/c1-43(2)29-52(73(121)103-57(31-46-19-21-49(110)22-20-46)80(128)108-28-11-17-59(108)77(125)104-58(41-131)76(124)102-56(34-62(86)112)71(119)95-40-66(116)107-27-12-18-60(107)81(129)130)97-64(114)38-92-63(113)37-93-70(118)53(32-47-15-9-25-89-35-47)100-74(122)55(33-48-36-90-42-96-48)98-65(115)39-94-78(126)67(44(3)109)105-79(127)68(83(4,5)132)106-75(123)54(30-45-13-7-6-8-14-45)101-72(120)51(16-10-26-91-82(87)88)99-69(117)50(84)23-24-61(85)111/h6-9,13-15,19-22,25,35-36,42-44,50-60,67-68,109-110,131-132H,10-12,16-18,23-24,26-34,37-41,84H2,1-5H3,(H2,85,111)(H2,86,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,87,88,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,67+,68+/m1/s1 RRDRVDPPAULRFT-ZHJKNKPASA-N 50270908 CHEMBL505603 IgG receptor FcRn large subunit p51 Homo sapiens 19000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270908&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935258 104115951 CHEMBL505603 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415694 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccn1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O22S2/c1-43(2)30-52(73(121)103-57(32-46-20-22-49(110)23-21-46)80(128)108-29-12-18-59(108)77(125)104-58(41-131)76(124)102-56(35-62(86)112)71(119)95-40-66(116)107-28-13-19-60(107)81(129)130)97-64(114)38-92-63(113)37-93-70(118)54(33-47-16-9-10-26-90-47)101-74(122)55(34-48-36-89-42-96-48)98-65(115)39-94-78(126)67(44(3)109)105-79(127)68(83(4,5)132)106-75(123)53(31-45-14-7-6-8-15-45)100-72(120)51(17-11-27-91-82(87)88)99-69(117)50(84)24-25-61(85)111/h6-10,14-16,20-23,26,36,42-44,50-60,67-68,109-110,131-132H,11-13,17-19,24-25,27-35,37-41,84H2,1-5H3,(H2,85,111)(H2,86,112)(H,89,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,120)(H,101,122)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,87,88,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58-,59+,60+,67+,68+/m1/s1 RSINYEGNQRXSBV-ZHJKNKPASA-N 50270907 CHEMBL526336 IgG receptor FcRn large subunit p51 Homo sapiens 1200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270907&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935257 104115950 CHEMBL526336 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415695 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H115F5N24O22S2/c1-39(2)26-48(74(126)108-53(28-42-17-19-44(115)20-18-42)81(133)113-25-10-15-55(113)78(130)109-54(37-136)77(129)107-52(31-58(92)117)72(124)100-36-62(121)112-24-11-16-56(112)82(134)135)102-60(119)34-97-59(118)33-98-71(123)51(30-45-63(85)65(87)67(89)66(88)64(45)86)106-75(127)50(29-43-32-95-38-101-43)103-61(120)35-99-79(131)68(40(3)114)110-80(132)69(84(4,5)137)111-76(128)49(27-41-12-7-6-8-13-41)105-73(125)47(14-9-23-96-83(93)94)104-70(122)46(90)21-22-57(91)116/h6-8,12-13,17-20,32,38-40,46-56,68-69,114-115,136-137H,9-11,14-16,21-31,33-37,90H2,1-5H3,(H2,91,116)(H2,92,117)(H,95,101)(H,97,118)(H,98,123)(H,99,131)(H,100,124)(H,102,119)(H,103,120)(H,104,122)(H,105,125)(H,106,127)(H,107,129)(H,108,126)(H,109,130)(H,110,132)(H,111,128)(H,134,135)(H4,93,94,96)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54-,55+,56+,68+,69+/m1/s1 FZFPNCVNLIHAHI-APCXSTTPSA-N 50270906 CHEMBL524517 IgG receptor FcRn large subunit p51 Homo sapiens 70000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270906&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935256 104115949 CHEMBL524517 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415696 COc1ccc(C[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N2CCC[C@H]2C(O)=O)cc1 InChI=1S/C85H122N24O23S2/c1-44(2)31-54(75(122)104-59(34-47-18-22-50(111)23-19-47)82(129)109-30-11-16-61(109)79(126)105-60(42-133)78(125)103-58(36-64(88)113)73(120)96-41-68(117)108-29-12-17-62(108)83(130)131)98-66(115)39-93-65(114)38-94-72(119)55(33-48-20-24-51(132-6)25-21-48)101-76(123)57(35-49-37-91-43-97-49)99-67(116)40-95-80(127)69(45(3)110)106-81(128)70(85(4,5)134)107-77(124)56(32-46-13-8-7-9-14-46)102-74(121)53(15-10-28-92-84(89)90)100-71(118)52(86)26-27-63(87)112/h7-9,13-14,18-25,37,43-45,52-62,69-70,110-111,133-134H,10-12,15-17,26-36,38-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60-,61+,62+,69+,70+/m1/s1 BXTLWSSWVCMERS-QVSLJBRWSA-N 50270905 CHEMBL506836 IgG receptor FcRn large subunit p51 Homo sapiens 18000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270905&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935255 104115948 CHEMBL506836 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415697 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H121N25O22S2/c1-43(2)30-53(74(122)104-58(33-47-19-23-50(111)24-20-47)81(129)109-29-10-15-60(109)78(126)105-59(41-132)77(125)103-57(35-63(88)113)72(120)96-40-67(117)108-28-11-16-61(108)82(130)131)98-65(115)38-93-64(114)37-94-71(119)54(32-46-17-21-48(85)22-18-46)101-75(123)56(34-49-36-91-42-97-49)99-66(116)39-95-79(127)68(44(3)110)106-80(128)69(84(4,5)133)107-76(124)55(31-45-12-7-6-8-13-45)102-73(121)52(14-9-27-92-83(89)90)100-70(118)51(86)25-26-62(87)112/h6-8,12-13,17-24,36,42-44,51-61,68-69,110-111,132-133H,9-11,14-16,25-35,37-41,85-86H2,1-5H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,123)(H,102,121)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60+,61+,68+,69+/m1/s1 CBEDAKGJOZPSSM-FSOLOWAYSA-N 50270904 CHEMBL509666 IgG receptor FcRn large subunit p51 Homo sapiens 1000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270904&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935254 104115947 CHEMBL509666 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415698 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)C(CCc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C76H110N20O18S2/c1-42(2)32-57(70(109)90-54(34-46-22-25-48(98)26-23-46)73(112)96-31-15-21-56(96)69(108)91-55(40-115)74(113)114)95(7)61(102)39-94(6)60(101)38-84-65(104)51(28-24-44-16-10-8-11-17-44)88-67(106)53(35-47-36-81-41-85-47)86-59(100)37-83-71(110)62(43(3)97)92-72(111)63(76(4,5)116)93-68(107)52(33-45-18-12-9-13-19-45)89-66(105)50(20-14-30-82-75(79)80)87-64(103)49(77)27-29-58(78)99/h8-13,16-19,22-23,25-26,36,41-43,49-57,62-63,97-98,115-116H,14-15,20-21,24,27-35,37-40,77H2,1-7H3,(H2,78,99)(H,81,85)(H,83,110)(H,84,104)(H,86,100)(H,87,103)(H,88,106)(H,89,105)(H,90,109)(H,91,108)(H,92,111)(H,93,107)(H,113,114)(H4,79,80,82)/t43-,49+,50+,51?,52+,53+,54+,55+,56+,57+,62+,63-/m1/s1 DILTVLYZGRXBLZ-HZYRTUFBSA-N 50270928 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[2-(2-{2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-4-phenylbutanamido}-N-methylacetamido)-N-methylacetamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL506482 IgG receptor FcRn large subunit p51 Homo sapiens 16000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270928&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935277 104115971 CHEMBL506482 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415699 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)C(C)(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C77H112N20O18S2/c1-41(2)30-51(67(107)93-55(33-45-20-24-48(99)25-21-45)73(113)97-29-13-17-57(97)70(110)94-56(39-116)74(114)115)88-60(102)37-84-59(101)36-85-65(105)52(32-44-18-22-46(23-19-44)76(4,5)6)91-68(108)54(34-47-35-82-40-87-47)89-61(103)38-86-71(111)62(42(3)98)95-72(112)63(77(7,8)117)96-69(109)53(31-43-14-10-9-11-15-43)92-66(106)50(16-12-28-83-75(80)81)90-64(104)49(78)26-27-58(79)100/h9-11,14-15,18-25,35,40-42,49-57,62-63,98-99,116-117H,12-13,16-17,26-34,36-39,78H2,1-8H3,(H2,79,100)(H,82,87)(H,84,101)(H,85,105)(H,86,111)(H,88,102)(H,89,103)(H,90,104)(H,91,108)(H,92,106)(H,93,107)(H,94,110)(H,95,112)(H,96,109)(H,114,115)(H4,80,81,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,62+,63-/m1/s1 QDYUXSPFOKZBRS-GAYZGZAASA-N 50270927 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-tert-butylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL442891 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270927&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935276 104115970 CHEMBL442891 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415700 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C79H108N20O18S2/c1-43(2)32-54(70(109)95-58(35-47-22-26-51(101)27-23-47)76(115)99-31-13-19-60(99)73(112)96-59(41-118)77(116)117)90-63(104)39-86-62(103)38-87-68(107)55(34-46-20-24-49(25-21-46)48-16-10-7-11-17-48)93-71(110)57(36-50-37-84-42-89-50)91-64(105)40-88-74(113)65(44(3)100)97-75(114)66(79(4,5)119)98-72(111)56(33-45-14-8-6-9-15-45)94-69(108)53(18-12-30-85-78(82)83)92-67(106)52(80)28-29-61(81)102/h6-11,14-17,20-27,37,42-44,52-60,65-66,100-101,118-119H,12-13,18-19,28-36,38-41,80H2,1-5H3,(H2,81,102)(H,84,89)(H,86,103)(H,87,107)(H,88,113)(H,90,104)(H,91,105)(H,92,106)(H,93,110)(H,94,108)(H,95,109)(H,96,112)(H,97,114)(H,98,111)(H,116,117)(H4,82,83,85)/t44-,52+,53+,54+,55+,56+,57+,58+,59+,60+,65+,66-/m1/s1 XGBIBVHZENYNNO-MXEFWCKWSA-N 50270926 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-phenylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501266 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270926&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935275 104115969 CHEMBL501266 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415701 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C79H108N20O18S2/c1-43(2)33-53(69(108)94-56(35-46-25-27-50(101)28-26-46)76(115)99-32-16-24-58(99)72(111)95-57(41-118)77(116)117)90-61(104)39-86-60(103)38-87-74(113)65(63(47-19-11-7-12-20-47)48-21-13-8-14-22-48)97-70(109)55(36-49-37-84-42-89-49)91-62(105)40-88-73(112)64(44(3)100)96-75(114)66(79(4,5)119)98-71(110)54(34-45-17-9-6-10-18-45)93-68(107)52(23-15-31-85-78(82)83)92-67(106)51(80)29-30-59(81)102/h6-14,17-22,25-28,37,42-44,51-58,63-66,100-101,118-119H,15-16,23-24,29-36,38-41,80H2,1-5H3,(H2,81,102)(H,84,89)(H,86,103)(H,87,113)(H,88,112)(H,90,104)(H,91,105)(H,92,106)(H,93,107)(H,94,108)(H,95,111)(H,96,114)(H,97,109)(H,98,110)(H,116,117)(H4,82,83,85)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,64+,65+,66-/m1/s1 DLTYRVBTJOGPLH-CXXFWUFESA-N 50270925 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3,3-diphenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL505681 IgG receptor FcRn large subunit p51 Homo sapiens 32000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270925&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935274 104115968 CHEMBL505681 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415702 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)27-48(64(104)90-52(30-42-17-21-45(96)22-18-42)70(110)94-26-10-14-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)49(29-41-15-19-43(74)20-16-41)88-65(105)51(31-44-32-79-37-84-44)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)50(28-40-11-7-6-8-12-40)89-63(103)47(13-9-25-80-72(77)78)87-61(101)46(75)23-24-55(76)97/h6-8,11-12,15-22,32,37-39,46-54,59-60,95-96,113-114H,9-10,13-14,23-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,105)(H,89,103)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 ZURRGFWMZVAYQR-YZOWQPKWSA-N 50270924 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504095 IgG receptor FcRn large subunit p51 Homo sapiens 43000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270924&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935273 104115967 CHEMBL504095 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415703 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O21S2/c1-44(2)30-52(73(118)101-57(33-48-20-11-6-12-21-48)80(125)106-29-14-23-60(106)78(123)103-58(41-128)76(121)100-56(35-63(85)109)71(116)93-40-67(113)105-28-15-24-61(105)81(126)127)95-65(111)38-90-64(110)37-91-70(115)53(31-46-16-7-4-8-17-46)98-75(120)55(34-49-36-88-43-94-49)96-66(112)39-92-79(124)68(45(3)107)104-77(122)59(42-129)102-74(119)54(32-47-18-9-5-10-19-47)99-72(117)51(22-13-27-89-82(86)87)97-69(114)50(83)25-26-62(84)108/h4-12,16-21,36,43-45,50-61,68,107,128-129H,13-15,22-35,37-42,83H2,1-3H3,(H2,84,108)(H2,85,109)(H,88,94)(H,90,110)(H,91,115)(H,92,124)(H,93,116)(H,95,111)(H,96,112)(H,97,114)(H,98,120)(H,99,117)(H,100,121)(H,101,118)(H,102,119)(H,103,123)(H,104,122)(H,126,127)(H4,86,87,89)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 WUNGGYWKLJHQSR-NNQBFYBFSA-N 50270929 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524661 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270929&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935278 104115972 CHEMBL524661 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415704 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O21S2/c1-44(2)30-52(73(118)101-57(33-48-20-11-6-12-21-48)80(125)106-29-14-23-60(106)78(123)103-58(41-128)76(121)100-56(35-63(85)109)71(116)93-40-67(113)105-28-15-24-61(105)81(126)127)95-65(111)38-90-64(110)37-91-70(115)53(31-46-16-7-4-8-17-46)98-75(120)55(34-49-36-88-43-94-49)96-66(112)39-92-79(124)68(45(3)107)104-77(122)59(42-129)102-74(119)54(32-47-18-9-5-10-19-47)99-72(117)51(22-13-27-89-82(86)87)97-69(114)50(83)25-26-62(84)108/h4-12,16-21,36,43-45,50-61,68,107,128-129H,13-15,22-35,37-42,83H2,1-3H3,(H2,84,108)(H2,85,109)(H,88,94)(H,90,110)(H,91,115)(H,92,124)(H,93,116)(H,95,111)(H,96,112)(H,97,114)(H,98,120)(H,99,117)(H,100,121)(H,101,118)(H,102,119)(H,103,123)(H,104,122)(H,126,127)(H4,86,87,89)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 WUNGGYWKLJHQSR-NNQBFYBFSA-N 50270929 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524661 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270929&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935278 104115972 CHEMBL524661 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415705 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC[NH+]=C(N)[NH-])NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1[N+]([O-])=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24S2/c1-43(2)29-52(74(122)103-57(32-47-22-23-49(111)34-61(47)109(132)133)81(129)108-28-13-20-59(108)78(126)104-58(41-134)77(125)102-56(35-63(87)113)72(120)95-40-67(117)107-27-14-21-60(107)82(130)131)97-65(115)38-92-64(114)37-93-71(119)53(30-45-15-8-6-9-16-45)100-75(123)55(33-48-36-90-42-96-48)98-66(116)39-94-79(127)68(44(3)110)105-80(128)69(84(4,5)135)106-76(124)54(31-46-17-10-7-11-18-46)101-73(121)51(19-12-26-91-83(88)89)99-70(118)50(85)24-25-62(86)112/h6-11,15-18,22-23,34,36,42-44,50-60,68-69,110H,12-14,19-21,24-33,35,37-41,85H2,1-5H3,(H27,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,111,112,113,114,115,116,118,119,120,121,122,123,124,125,126,127,128,130,131,134,135)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,68+,69-/m1/s1 FQRXDVNTJGLXPV-NUXZCYAQSA-N 50270936 CHEMBL499946 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270936&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585816 104115979 CHEMBL499946 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415706 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O21S2/c1-44(2)31-52(73(120)103-57(34-48-21-12-13-27-90-48)80(127)108-30-15-23-59(108)77(124)104-58(42-130)76(123)102-56(36-62(86)111)71(118)95-41-66(115)107-29-16-24-60(107)81(128)129)97-64(113)39-92-63(112)38-93-70(117)53(32-46-17-8-6-9-18-46)100-74(121)55(35-49-37-89-43-96-49)98-65(114)40-94-78(125)67(45(3)109)105-79(126)68(83(4,5)131)106-75(122)54(33-47-19-10-7-11-20-47)101-72(119)51(22-14-28-91-82(87)88)99-69(116)50(84)25-26-61(85)110/h6-13,17-21,27,37,43-45,50-60,67-68,109,130-131H,14-16,22-26,28-36,38-42,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,89,96)(H,92,112)(H,93,117)(H,94,125)(H,95,118)(H,97,113)(H,98,114)(H,99,116)(H,100,121)(H,101,119)(H,102,123)(H,103,120)(H,104,124)(H,105,126)(H,106,122)(H,128,129)(H4,87,88,91)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,67+,68-/m1/s1 FEQFSZIRWSWSPI-VTYKBERMSA-N 50270933 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(pyridin-2-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499501 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270933&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935282 104115976 CHEMBL499501 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415707 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H115F5N24O21S2/c1-40(2)27-48(74(125)108-53(31-45-63(85)65(87)67(89)66(88)64(45)86)81(132)113-26-13-20-55(113)78(129)109-54(38-135)77(128)107-52(32-58(92)116)72(123)100-37-62(120)112-25-14-21-56(112)82(133)134)102-60(118)35-97-59(117)34-98-71(122)49(28-42-15-8-6-9-16-42)105-75(126)51(30-44-33-95-39-101-44)103-61(119)36-99-79(130)68(41(3)114)110-80(131)69(84(4,5)136)111-76(127)50(29-43-17-10-7-11-18-43)106-73(124)47(19-12-24-96-83(93)94)104-70(121)46(90)22-23-57(91)115/h6-11,15-18,33,39-41,46-56,68-69,114,135-136H,12-14,19-32,34-38,90H2,1-5H3,(H2,91,115)(H2,92,116)(H,95,101)(H,97,117)(H,98,122)(H,99,130)(H,100,123)(H,102,118)(H,103,119)(H,104,121)(H,105,126)(H,106,124)(H,107,128)(H,108,125)(H,109,129)(H,110,131)(H,111,127)(H,133,134)(H4,93,94,96)/t41-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,68+,69-/m1/s1 BPWYCEIDCXOGLC-UOFYIZQISA-N 50270932 CHEMBL524877 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270932&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935281 104115975 CHEMBL524877 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415708 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119FN24O21S2/c1-44(2)31-53(74(121)104-58(34-48-22-24-49(85)25-23-48)81(128)109-30-13-20-60(109)78(125)105-59(42-131)77(124)103-57(36-63(88)112)72(119)96-41-67(116)108-29-14-21-61(108)82(129)130)98-65(114)39-93-64(113)38-94-71(118)54(32-46-15-8-6-9-16-46)101-75(122)56(35-50-37-91-43-97-50)99-66(115)40-95-79(126)68(45(3)110)106-80(127)69(84(4,5)132)107-76(123)55(33-47-17-10-7-11-18-47)102-73(120)52(19-12-28-92-83(89)90)100-70(117)51(86)26-27-62(87)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110,131-132H,12-14,19-21,26-36,38-42,86H2,1-5H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 JRGYKMAKLGWOAS-JFFCSCEESA-N 50270782 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-fluorophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500788 IgG receptor FcRn large subunit p51 Homo sapiens 2200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270782&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935177 104115844 CHEMBL500788 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415709 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC[NH+]=C(N)[NH-])NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1[N+]([O-])=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24S2/c1-43(2)29-52(74(122)103-57(32-47-22-23-49(111)34-61(47)109(132)133)81(129)108-28-13-20-59(108)78(126)104-58(41-134)77(125)102-56(35-63(87)113)72(120)95-40-67(117)107-27-14-21-60(107)82(130)131)97-65(115)38-92-64(114)37-93-71(119)53(30-45-15-8-6-9-16-45)100-75(123)55(33-48-36-90-42-96-48)98-66(116)39-94-79(127)68(44(3)110)105-80(128)69(84(4,5)135)106-76(124)54(31-46-17-10-7-11-18-46)101-73(121)51(19-12-26-91-83(88)89)99-70(118)50(85)24-25-62(86)112/h6-11,15-18,22-23,34,36,42-44,50-60,68-69,110H,12-14,19-21,24-33,35,37-41,85H2,1-5H3,(H27,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,111,112,113,114,115,116,118,119,120,121,122,123,124,125,126,127,128,130,131,134,135)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,68+,69-/m1/s1 FQRXDVNTJGLXPV-NUXZCYAQSA-N 50270936 CHEMBL499946 IgG receptor FcRn large subunit p51 Homo sapiens 290000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270936&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585816 104115979 CHEMBL499946 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415710 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC[NH+]=C(N)[NH-])NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(cc1)[N+]([O-])=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O23S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(25-23-48)109(131)132)81(128)108-30-13-20-60(108)78(125)104-59(42-133)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)110)105-80(127)69(84(4,5)134)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H26,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,111,112,113,114,115,117,118,119,120,121,122,123,124,125,126,127,129,130,133,134)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 VTMMFSPOIPIMCJ-JFFCSCEESA-N 50270935 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-nitrophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL502881 IgG receptor FcRn large subunit p51 Homo sapiens 180000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270935&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585815 104115978 CHEMBL502881 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415711 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1cccnc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O21S2/c1-44(2)30-52(73(120)103-57(33-48-20-12-26-89-36-48)80(127)108-29-14-22-59(108)77(124)104-58(42-130)76(123)102-56(35-62(86)111)71(118)95-41-66(115)107-28-15-23-60(107)81(128)129)97-64(113)39-92-63(112)38-93-70(117)53(31-46-16-8-6-9-17-46)100-74(121)55(34-49-37-90-43-96-49)98-65(114)40-94-78(125)67(45(3)109)105-79(126)68(83(4,5)131)106-75(122)54(32-47-18-10-7-11-19-47)101-72(119)51(21-13-27-91-82(87)88)99-69(116)50(84)24-25-61(85)110/h6-12,16-20,26,36-37,43-45,50-60,67-68,109,130-131H,13-15,21-25,27-35,38-42,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,90,96)(H,92,112)(H,93,117)(H,94,125)(H,95,118)(H,97,113)(H,98,114)(H,99,116)(H,100,121)(H,101,119)(H,102,123)(H,103,120)(H,104,124)(H,105,126)(H,106,122)(H,128,129)(H4,87,88,91)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,67+,68-/m1/s1 QLTRONHDULIURH-VTYKBERMSA-N 50270934 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(pyridin-3-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500995 IgG receptor FcRn large subunit p51 Homo sapiens 34000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270934&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935283 104115977 CHEMBL500995 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415712 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O21S2/c1-44(2)31-52(73(120)103-57(34-48-21-12-13-27-90-48)80(127)108-30-15-23-59(108)77(124)104-58(42-130)76(123)102-56(36-62(86)111)71(118)95-41-66(115)107-29-16-24-60(107)81(128)129)97-64(113)39-92-63(112)38-93-70(117)53(32-46-17-8-6-9-18-46)100-74(121)55(35-49-37-89-43-96-49)98-65(114)40-94-78(125)67(45(3)109)105-79(126)68(83(4,5)131)106-75(122)54(33-47-19-10-7-11-20-47)101-72(119)51(22-14-28-91-82(87)88)99-69(116)50(84)25-26-61(85)110/h6-13,17-21,27,37,43-45,50-60,67-68,109,130-131H,14-16,22-26,28-36,38-42,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,89,96)(H,92,112)(H,93,117)(H,94,125)(H,95,118)(H,97,113)(H,98,114)(H,99,116)(H,100,121)(H,101,119)(H,102,123)(H,103,120)(H,104,124)(H,105,126)(H,106,122)(H,128,129)(H4,87,88,91)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,67+,68-/m1/s1 FEQFSZIRWSWSPI-VTYKBERMSA-N 50270933 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(pyridin-2-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499501 IgG receptor FcRn large subunit p51 Homo sapiens 120000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270933&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935282 104115976 CHEMBL499501 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415713 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H115F5N24O21S2/c1-40(2)27-48(74(125)108-53(31-45-63(85)65(87)67(89)66(88)64(45)86)81(132)113-26-13-20-55(113)78(129)109-54(38-135)77(128)107-52(32-58(92)116)72(123)100-37-62(120)112-25-14-21-56(112)82(133)134)102-60(118)35-97-59(117)34-98-71(122)49(28-42-15-8-6-9-16-42)105-75(126)51(30-44-33-95-39-101-44)103-61(119)36-99-79(130)68(41(3)114)110-80(131)69(84(4,5)136)111-76(127)50(29-43-17-10-7-11-18-43)106-73(124)47(19-12-24-96-83(93)94)104-70(121)46(90)22-23-57(91)115/h6-11,15-18,33,39-41,46-56,68-69,114,135-136H,12-14,19-32,34-38,90H2,1-5H3,(H2,91,115)(H2,92,116)(H,95,101)(H,97,117)(H,98,122)(H,99,130)(H,100,123)(H,102,118)(H,103,119)(H,104,121)(H,105,126)(H,106,124)(H,107,128)(H,108,125)(H,109,129)(H,110,131)(H,111,127)(H,133,134)(H4,93,94,96)/t41-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,68+,69-/m1/s1 BPWYCEIDCXOGLC-UOFYIZQISA-N 50270932 CHEMBL524877 IgG receptor FcRn large subunit p51 Homo sapiens 72000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270932&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935281 104115975 CHEMBL524877 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415714 COc1ccc(C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N2CCC[C@H]2C(O)=O)cc1 InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(121)104-59(35-49-23-25-51(131-6)26-24-49)82(128)109-31-14-21-61(109)79(125)105-60(43-132)78(124)103-58(37-64(88)112)73(119)96-42-68(116)108-30-15-22-62(108)83(129)130)98-66(114)40-93-65(113)39-94-72(118)55(33-47-16-9-7-10-17-47)101-76(122)57(36-50-38-91-44-97-50)99-67(115)41-95-80(126)69(46(3)110)106-81(127)70(85(4,5)133)107-77(123)56(34-48-18-11-8-12-19-48)102-74(120)53(20-13-29-92-84(89)90)100-71(117)52(86)27-28-63(87)111/h7-12,16-19,23-26,38,44-46,52-62,69-70,110,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 DEAKTGBWRKXUKD-PUBHSFPPSA-N 50270931 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-methoxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507073 IgG receptor FcRn large subunit p51 Homo sapiens 31000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270931&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935280 104115974 CHEMBL507073 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415715 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H121N25O21S2/c1-44(2)31-53(74(121)104-58(34-48-22-24-49(85)25-23-48)81(128)109-30-13-20-60(109)78(125)105-59(42-131)77(124)103-57(36-63(88)112)72(119)96-41-67(116)108-29-14-21-61(108)82(129)130)98-65(114)39-93-64(113)38-94-71(118)54(32-46-15-8-6-9-16-46)101-75(122)56(35-50-37-91-43-97-50)99-66(115)40-95-79(126)68(45(3)110)106-80(127)69(84(4,5)132)107-76(123)55(33-47-17-10-7-11-18-47)102-73(120)52(19-12-28-92-83(89)90)100-70(117)51(86)26-27-62(87)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110,131-132H,12-14,19-21,26-36,38-42,85-86H2,1-5H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 OTLQEWPRYYQTPS-JFFCSCEESA-N 50270930 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-aminophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504269 IgG receptor FcRn large subunit p51 Homo sapiens 34000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270930&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935279 104115973 CHEMBL504269 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415716 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)C(CCc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C76H110N20O18S2/c1-42(2)32-57(70(109)90-54(34-46-22-25-48(98)26-23-46)73(112)96-31-15-21-56(96)69(108)91-55(40-115)74(113)114)95(7)61(102)39-94(6)60(101)38-84-65(104)51(28-24-44-16-10-8-11-17-44)88-67(106)53(35-47-36-81-41-85-47)86-59(100)37-83-71(110)62(43(3)97)92-72(111)63(76(4,5)116)93-68(107)52(33-45-18-12-9-13-19-45)89-66(105)50(20-14-30-82-75(79)80)87-64(103)49(77)27-29-58(78)99/h8-13,16-19,22-23,25-26,36,41-43,49-57,62-63,97-98,115-116H,14-15,20-21,24,27-35,37-40,77H2,1-7H3,(H2,78,99)(H,81,85)(H,83,110)(H,84,104)(H,86,100)(H,87,103)(H,88,106)(H,89,105)(H,90,109)(H,91,108)(H,92,111)(H,93,107)(H,113,114)(H4,79,80,82)/t43-,49+,50+,51?,52+,53+,54+,55+,56+,57+,62+,63-/m1/s1 DILTVLYZGRXBLZ-HZYRTUFBSA-N 50270928 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[2-(2-{2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-4-phenylbutanamido}-N-methylacetamido)-N-methylacetamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL506482 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270928&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935277 104115971 CHEMBL506482 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415717 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)C(C)(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C77H112N20O18S2/c1-41(2)30-51(67(107)93-55(33-45-20-24-48(99)25-21-45)73(113)97-29-13-17-57(97)70(110)94-56(39-116)74(114)115)88-60(102)37-84-59(101)36-85-65(105)52(32-44-18-22-46(23-19-44)76(4,5)6)91-68(108)54(34-47-35-82-40-87-47)89-61(103)38-86-71(111)62(42(3)98)95-72(112)63(77(7,8)117)96-69(109)53(31-43-14-10-9-11-15-43)92-66(106)50(16-12-28-83-75(80)81)90-64(104)49(78)26-27-58(79)100/h9-11,14-15,18-25,35,40-42,49-57,62-63,98-99,116-117H,12-13,16-17,26-34,36-39,78H2,1-8H3,(H2,79,100)(H,82,87)(H,84,101)(H,85,105)(H,86,111)(H,88,102)(H,89,103)(H,90,104)(H,91,108)(H,92,106)(H,93,107)(H,94,110)(H,95,112)(H,96,109)(H,114,115)(H4,80,81,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,62+,63-/m1/s1 QDYUXSPFOKZBRS-GAYZGZAASA-N 50270927 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-tert-butylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL442891 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270927&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935276 104115970 CHEMBL442891 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415718 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C79H108N20O18S2/c1-43(2)32-54(70(109)95-58(35-47-22-26-51(101)27-23-47)76(115)99-31-13-19-60(99)73(112)96-59(41-118)77(116)117)90-63(104)39-86-62(103)38-87-68(107)55(34-46-20-24-49(25-21-46)48-16-10-7-11-17-48)93-71(110)57(36-50-37-84-42-89-50)91-64(105)40-88-74(113)65(44(3)100)97-75(114)66(79(4,5)119)98-72(111)56(33-45-14-8-6-9-15-45)94-69(108)53(18-12-30-85-78(82)83)92-67(106)52(80)28-29-61(81)102/h6-11,14-17,20-27,37,42-44,52-60,65-66,100-101,118-119H,12-13,18-19,28-36,38-41,80H2,1-5H3,(H2,81,102)(H,84,89)(H,86,103)(H,87,107)(H,88,113)(H,90,104)(H,91,105)(H,92,106)(H,93,110)(H,94,108)(H,95,109)(H,96,112)(H,97,114)(H,98,111)(H,116,117)(H4,82,83,85)/t44-,52+,53+,54+,55+,56+,57+,58+,59+,60+,65+,66-/m1/s1 XGBIBVHZENYNNO-MXEFWCKWSA-N 50270926 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-phenylphenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501266 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270926&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935275 104115969 CHEMBL501266 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415719 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C79H108N20O18S2/c1-43(2)33-53(69(108)94-56(35-46-25-27-50(101)28-26-46)76(115)99-32-16-24-58(99)72(111)95-57(41-118)77(116)117)90-61(104)39-86-60(103)38-87-74(113)65(63(47-19-11-7-12-20-47)48-21-13-8-14-22-48)97-70(109)55(36-49-37-84-42-89-49)91-62(105)40-88-73(112)64(44(3)100)96-75(114)66(79(4,5)119)98-71(110)54(34-45-17-9-6-10-18-45)93-68(107)52(23-15-31-85-78(82)83)92-67(106)51(80)29-30-59(81)102/h6-14,17-22,25-28,37,42-44,51-58,63-66,100-101,118-119H,15-16,23-24,29-36,38-41,80H2,1-5H3,(H2,81,102)(H,84,89)(H,86,103)(H,87,113)(H,88,112)(H,90,104)(H,91,105)(H,92,106)(H,93,107)(H,94,108)(H,95,111)(H,96,114)(H,97,109)(H,98,110)(H,116,117)(H4,82,83,85)/t44-,51+,52+,53+,54+,55+,56+,57+,58+,64+,65+,66-/m1/s1 DLTYRVBTJOGPLH-CXXFWUFESA-N 50270925 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3,3-diphenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL505681 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270925&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935274 104115968 CHEMBL505681 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415720 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)27-48(64(104)90-52(30-42-17-21-45(96)22-18-42)70(110)94-26-10-14-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)49(29-41-15-19-43(74)20-16-41)88-65(105)51(31-44-32-79-37-84-44)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)50(28-40-11-7-6-8-12-40)89-63(103)47(13-9-25-80-72(77)78)87-61(101)46(75)23-24-55(76)97/h6-8,11-12,15-22,32,37-39,46-54,59-60,95-96,113-114H,9-10,13-14,23-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,105)(H,89,103)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 ZURRGFWMZVAYQR-YZOWQPKWSA-N 50270924 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(4-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504095 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270924&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935273 104115967 CHEMBL504095 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415721 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)26-48(64(104)90-52(29-41-18-20-45(96)21-19-41)70(110)94-25-11-17-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)49(30-42-14-9-15-43(74)27-42)88-65(105)51(31-44-32-79-37-84-44)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)50(28-40-12-7-6-8-13-40)89-63(103)47(16-10-24-80-72(77)78)87-61(101)46(75)22-23-55(76)97/h6-9,12-15,18-21,27,32,37-39,46-54,59-60,95-96,113-114H,10-11,16-17,22-26,28-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,105)(H,89,103)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 SQAMZKNFJMVLPC-YZOWQPKWSA-N 50270923 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(3-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL508126 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270923&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935272 104115966 CHEMBL508126 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415722 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1Cl)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103ClN20O18S2/c1-38(2)27-48(64(104)90-52(29-41-19-21-44(96)22-20-41)70(110)94-26-12-18-54(94)67(107)91-53(36-113)71(111)112)85-57(99)34-81-56(98)33-82-62(102)50(30-42-15-9-10-16-45(42)74)89-65(105)51(31-43-32-79-37-84-43)86-58(100)35-83-68(108)59(39(3)95)92-69(109)60(73(4,5)114)93-66(106)49(28-40-13-7-6-8-14-40)88-63(103)47(17-11-25-80-72(77)78)87-61(101)46(75)23-24-55(76)97/h6-10,13-16,19-22,32,37-39,46-54,59-60,95-96,113-114H,11-12,17-18,23-31,33-36,75H2,1-5H3,(H2,76,97)(H,79,84)(H,81,98)(H,82,102)(H,83,108)(H,85,99)(H,86,100)(H,87,101)(H,88,103)(H,89,105)(H,90,104)(H,91,107)(H,92,109)(H,93,106)(H,111,112)(H4,77,78,80)/t39-,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+,60-/m1/s1 DPKBOVLGLVWKOG-YZOWQPKWSA-N 50270922 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-(2-chlorophenyl)propanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525594 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270922&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935271 104115965 CHEMBL525594 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415723 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119FN24O21S2/c1-44(2)31-53(74(121)104-58(34-48-22-24-49(85)25-23-48)81(128)109-30-13-20-60(109)78(125)105-59(42-131)77(124)103-57(36-63(88)112)72(119)96-41-67(116)108-29-14-21-61(108)82(129)130)98-65(114)39-93-64(113)38-94-71(118)54(32-46-15-8-6-9-16-46)101-75(122)56(35-50-37-91-43-97-50)99-66(115)40-95-79(126)68(45(3)110)106-80(127)69(84(4,5)132)107-76(123)55(33-47-17-10-7-11-18-47)102-73(120)52(19-12-28-92-83(89)90)100-70(117)51(86)26-27-62(87)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110,131-132H,12-14,19-21,26-36,38-42,86H2,1-5H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 JRGYKMAKLGWOAS-JFFCSCEESA-N 50270782 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-fluorophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500788 IgG receptor FcRn large subunit p51 Homo sapiens 26000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270782&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935177 104115844 CHEMBL500788 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415724 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC[NH+]=C(N)[NH-])NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(cc1)[N+]([O-])=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O23S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(25-23-48)109(131)132)81(128)108-30-13-20-60(108)78(125)104-59(42-133)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)110)105-80(127)69(84(4,5)134)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H26,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,111,112,113,114,115,117,118,119,120,121,122,123,124,125,126,127,129,130,133,134)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 VTMMFSPOIPIMCJ-JFFCSCEESA-N 50270935 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-nitrophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL502881 IgG receptor FcRn large subunit p51 Homo sapiens 122000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270935&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585815 104115978 CHEMBL502881 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415725 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1cccnc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H119N25O21S2/c1-44(2)30-52(73(120)103-57(33-48-20-12-26-89-36-48)80(127)108-29-14-22-59(108)77(124)104-58(42-130)76(123)102-56(35-62(86)111)71(118)95-41-66(115)107-28-15-23-60(107)81(128)129)97-64(113)39-92-63(112)38-93-70(117)53(31-46-16-8-6-9-17-46)100-74(121)55(34-49-37-90-43-96-49)98-65(114)40-94-78(125)67(45(3)109)105-79(126)68(83(4,5)131)106-75(122)54(32-47-18-10-7-11-19-47)101-72(119)51(21-13-27-91-82(87)88)99-69(116)50(84)24-25-61(85)110/h6-12,16-20,26,36-37,43-45,50-60,67-68,109,130-131H,13-15,21-25,27-35,38-42,84H2,1-5H3,(H2,85,110)(H2,86,111)(H,90,96)(H,92,112)(H,93,117)(H,94,125)(H,95,118)(H,97,113)(H,98,114)(H,99,116)(H,100,121)(H,101,119)(H,102,123)(H,103,120)(H,104,124)(H,105,126)(H,106,122)(H,128,129)(H4,87,88,91)/t45-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,67+,68-/m1/s1 QLTRONHDULIURH-VTYKBERMSA-N 50270934 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(pyridin-3-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500995 IgG receptor FcRn large subunit p51 Homo sapiens 92000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270934&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935283 104115977 CHEMBL500995 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415726 COc1ccc(C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N2CCC[C@H]2C(O)=O)cc1 InChI=1S/C85H122N24O22S2/c1-45(2)32-54(75(121)104-59(35-49-23-25-51(131-6)26-24-49)82(128)109-31-14-21-61(109)79(125)105-60(43-132)78(124)103-58(37-64(88)112)73(119)96-42-68(116)108-30-15-22-62(108)83(129)130)98-66(114)40-93-65(113)39-94-72(118)55(33-47-16-9-7-10-17-47)101-76(122)57(36-50-38-91-44-97-50)99-67(115)41-95-80(126)69(46(3)110)106-81(127)70(85(4,5)133)107-77(123)56(34-48-18-11-8-12-19-48)102-74(120)53(20-13-29-92-84(89)90)100-71(117)52(86)27-28-63(87)111/h7-12,16-19,23-26,38,44-46,52-62,69-70,110,132-133H,13-15,20-22,27-37,39-43,86H2,1-6H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+,70-/m1/s1 DEAKTGBWRKXUKD-PUBHSFPPSA-N 50270931 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-methoxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507073 IgG receptor FcRn large subunit p51 Homo sapiens 120000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270931&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935280 104115974 CHEMBL507073 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415727 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H121N25O21S2/c1-44(2)31-53(74(121)104-58(34-48-22-24-49(85)25-23-48)81(128)109-30-13-20-60(109)78(125)105-59(42-131)77(124)103-57(36-63(88)112)72(119)96-41-67(116)108-29-14-21-61(108)82(129)130)98-65(114)39-93-64(113)38-94-71(118)54(32-46-15-8-6-9-16-46)101-75(122)56(35-50-37-91-43-97-50)99-66(115)40-95-79(126)68(45(3)110)106-80(127)69(84(4,5)132)107-76(123)55(33-47-17-10-7-11-18-47)102-73(120)52(19-12-28-92-83(89)90)100-70(117)51(86)26-27-62(87)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,110,131-132H,12-14,19-21,26-36,38-42,85-86H2,1-5H3,(H2,87,111)(H2,88,112)(H,91,97)(H,93,113)(H,94,118)(H,95,126)(H,96,119)(H,98,114)(H,99,115)(H,100,117)(H,101,122)(H,102,120)(H,103,124)(H,104,121)(H,105,125)(H,106,127)(H,107,123)(H,129,130)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+,69-/m1/s1 OTLQEWPRYYQTPS-JFFCSCEESA-N 50270930 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-aminophenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL504269 IgG receptor FcRn large subunit p51 Homo sapiens 110000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270930&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935279 104115973 CHEMBL504269 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415728 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C67H98N16O16S2/c1-37(2)29-50(61(94)77-47(32-42-23-25-43(85)26-24-42)64(97)83-28-16-22-49(83)60(93)78-48(36-100)65(98)99)82(8)53(88)35-81(7)52(87)34-73-58(91)45(30-40-17-11-9-12-18-40)75-56(89)38(3)74-51(86)33-72-62(95)54(39(4)84)79-63(96)55(67(5,6)101)80-59(92)46(31-41-19-13-10-14-20-41)76-57(90)44(68)21-15-27-71-66(69)70/h9-14,17-20,23-26,37-39,44-50,54-55,84-85,100-101H,15-16,21-22,27-36,68H2,1-8H3,(H,72,95)(H,73,91)(H,74,86)(H,75,89)(H,76,90)(H,77,94)(H,78,93)(H,79,96)(H,80,92)(H,98,99)(H4,69,70,71)/t38-,39+,44-,45-,46-,47-,48-,49-,50-,54-,55+/m0/s1 PLTHUPZHFFCLIW-SFICEKSFSA-N 50270953 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525232 IgG receptor FcRn large subunit p51 Homo sapiens >100000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270953&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585833 104115996 CHEMBL525232 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415729 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H102N16O16S2/c1-42(2)33-56(67(100)83-53(37-47-27-29-48(91)30-28-47)70(103)89-32-18-26-55(89)66(99)84-54(41-106)71(104)105)88(7)59(94)40-87(6)58(93)39-79-63(96)50(34-44-19-11-8-12-20-44)82-64(97)51(35-45-21-13-9-14-22-45)80-57(92)38-78-68(101)60(43(3)90)85-69(102)61(73(4,5)107)86-65(98)52(36-46-23-15-10-16-24-46)81-62(95)49(74)25-17-31-77-72(75)76/h8-16,19-24,27-30,42-43,49-56,60-61,90-91,106-107H,17-18,25-26,31-41,74H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,75,76,77)/t43-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 XPNACTKSNQJUKY-IQKMKRTQSA-N 50270952 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-phenylpropanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524718 IgG receptor FcRn large subunit p51 Homo sapiens 27000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270952&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585832 104115995 CHEMBL524718 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415730 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCNCC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-25,41-42,46,48-55,59-60,76,90-91,106-107H,14-15,20-21,26-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 BMLIWXUJOHYWPK-OFRDJWLHSA-N 50270951 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525431 IgG receptor FcRn large subunit p51 Homo sapiens 85000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270951&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585831 104115994 CHEMBL525431 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415731 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCNC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-13,17-20,24-27,41-42,46,48-55,59-60,76,90-91,106-107H,14-16,21-23,28-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,46?,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 SDEOUMVKASFBFG-SQUBLMHESA-N 50270950 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526499 IgG receptor FcRn large subunit p51 Homo sapiens 6300 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270950&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585830 104115993 CHEMBL526499 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415732 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cc[nH]c1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H101N17O16S2/c1-40(2)30-54(65(99)82-51(33-44-22-24-46(90)25-23-44)68(102)88-29-15-21-53(88)64(98)83-52(39-105)69(103)104)87(7)57(93)38-86(6)56(92)37-78-61(95)48(31-42-16-10-8-11-17-42)81-62(96)49(34-45-26-28-75-35-45)79-55(91)36-77-66(100)58(41(3)89)84-67(101)59(71(4,5)106)85-63(97)50(32-43-18-12-9-13-19-43)80-60(94)47(72)20-14-27-76-70(73)74/h8-13,16-19,22-26,28,35,40-41,47-54,58-59,75,89-90,105-106H,14-15,20-21,27,29-34,36-39,72H2,1-7H3,(H,77,100)(H,78,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,73,74,76)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 NGAVDNSZVZELRG-PMHNZZKJSA-N 50270949 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-pyrrol-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL510720 IgG receptor FcRn large subunit p51 Homo sapiens 150000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270949&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585829 104115992 CHEMBL510720 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415733 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 VDTFZUDODVYEAQ-GAIGFMGPSA-N 50270948 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-aminophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504837 IgG receptor FcRn large subunit p51 Homo sapiens 4600 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270948&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585828 104115991 CHEMBL504837 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415734 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 LTJSIONUIYPBNM-GAIGFMGPSA-N 50270947 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-carbamimidamidophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504003 IgG receptor FcRn large subunit p51 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270947&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935284 104115990 CHEMBL504003 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415735 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N19O16S2/c1-39(2)31-52(63(100)83-49(34-43-24-26-44(91)27-25-43)66(103)89-30-16-23-51(89)62(99)84-50(38-106)67(104)105)88(7)55(94)37-87(6)54(93)36-79-59(96)47(32-41-17-10-8-11-18-41)82-60(97)46(22-15-29-77-69(74)75)80-53(92)35-78-64(101)56(40(3)90)85-65(102)57(70(4,5)107)86-61(98)48(33-42-19-12-9-13-20-42)81-58(95)45(71)21-14-28-76-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,90-91,106-107H,14-16,21-23,28-38,71H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,72,73,76)(H4,74,75,77)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 UYTJXNOKSSRZIA-ZTUWISBESA-N 50270946 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL509335 IgG receptor FcRn large subunit p51 Homo sapiens 5500 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270946&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585826 104115989 CHEMBL509335 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415736 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N17O16S2/c1-40(2)32-53(64(98)81-50(35-44-25-27-45(89)28-26-44)67(101)87-31-17-24-52(87)63(97)82-51(39-104)68(102)103)86(7)56(92)38-85(6)55(91)37-77-60(94)48(33-42-18-10-8-11-19-42)80-61(95)47(23-14-15-29-71)78-54(90)36-76-65(99)57(41(3)88)83-66(100)58(70(4,5)105)84-62(96)49(34-43-20-12-9-13-21-43)79-59(93)46(72)22-16-30-75-69(73)74/h8-13,18-21,25-28,40-41,46-53,57-58,88-89,104-105H,14-17,22-24,29-39,71-72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 ZWGRTIDGLKIEMS-XMFJQSQOSA-N 50270945 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-6-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}hexanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524297 IgG receptor FcRn large subunit p51 Homo sapiens 40000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270945&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585825 104115988 CHEMBL524297 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415737 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H103N17O16S2/c1-39(2)31-52(63(97)80-49(34-43-24-26-44(88)27-25-43)66(100)86-30-16-23-51(86)62(96)81-50(38-103)67(101)102)85(7)55(91)37-84(6)54(90)36-76-59(93)47(32-41-17-10-8-11-18-41)79-60(94)46(22-14-28-70)77-53(89)35-75-64(98)56(40(3)87)82-65(99)57(69(4,5)104)83-61(95)48(33-42-19-12-9-13-20-42)78-58(92)45(71)21-15-29-74-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,87-88,103-104H,14-16,21-23,28-38,70-71H2,1-7H3,(H,75,98)(H,76,93)(H,77,89)(H,78,92)(H,79,94)(H,80,97)(H,81,96)(H,82,99)(H,83,95)(H,101,102)(H4,72,73,74)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 BSBUVESIVQAPEC-ZTUWISBESA-N 50270944 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-5-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}pentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504336 IgG receptor FcRn large subunit p51 Homo sapiens 12000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270944&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585824 104115987 CHEMBL504336 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415738 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C68H101N17O16S2/c1-38(2)30-51(62(96)79-48(33-42-22-24-43(87)25-23-42)65(99)85-29-15-21-50(85)61(95)80-49(37-102)66(100)101)84(7)54(90)36-83(6)53(89)35-75-58(92)46(31-40-16-10-8-11-17-40)78-59(93)45(26-27-69)76-52(88)34-74-63(97)55(39(3)86)81-64(98)56(68(4,5)103)82-60(94)47(32-41-18-12-9-13-19-41)77-57(91)44(70)20-14-28-73-67(71)72/h8-13,16-19,22-25,38-39,44-51,55-56,86-87,102-103H,14-15,20-21,26-37,69-70H2,1-7H3,(H,74,97)(H,75,92)(H,76,88)(H,77,91)(H,78,93)(H,79,96)(H,80,95)(H,81,98)(H,82,94)(H,100,101)(H4,71,72,73)/t39-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1 VDVYPUQKQQZAQP-VDKARCBXSA-N 50270916 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-4-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}butanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526300 IgG receptor FcRn large subunit p51 Homo sapiens 16000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270916&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585796 104115959 CHEMBL526300 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415739 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccsc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N16O16S3/c1-40(2)30-54(65(98)81-51(33-44-22-24-46(89)25-23-44)68(101)87-28-15-21-53(87)64(97)82-52(38-104)69(102)103)86(7)57(92)37-85(6)56(91)36-77-61(94)48(31-42-16-10-8-11-17-42)80-62(95)49(34-45-26-29-106-39-45)78-55(90)35-76-66(99)58(41(3)88)83-67(100)59(71(4,5)105)84-63(96)50(32-43-18-12-9-13-19-43)79-60(93)47(72)20-14-27-75-70(73)74/h8-13,16-19,22-26,29,39-41,47-54,58-59,88-89,104-105H,14-15,20-21,27-28,30-38,72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 BFALDNZBLNDWMU-PMHNZZKJSA-N 50270943 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(thiophen-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501094 IgG receptor FcRn large subunit p51 Homo sapiens 45000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270943&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585823 104115986 CHEMBL501094 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415740 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccncc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-27,29-30,41-42,48-55,59-60,90-91,106-107H,14-15,20-21,28,31-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 RBGABFZURPEVTF-OFRDJWLHSA-N 50270942 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL503673 IgG receptor FcRn large subunit p51 Homo sapiens 1300 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270942&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585822 104115985 CHEMBL503673 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415741 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccnc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-14,17-21,24-28,36,41-42,48-55,59-60,90-91,106-107H,15-16,22-23,29-35,37-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 HXAVKIDMUJTIEM-OFRDJWLHSA-N 50270941 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501395 IgG receptor FcRn large subunit p51 Homo sapiens 1200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270941&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585821 104115984 CHEMBL501395 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415742 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(35-45-25-27-47(91)28-26-45)69(103)89-31-17-24-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-18-10-8-11-19-43)82-63(97)51(36-46-22-14-15-29-76-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)50(34-44-20-12-9-13-21-44)81-61(95)48(73)23-16-30-77-71(74)75/h8-15,18-22,25-29,41-42,48-55,59-60,90-91,106-107H,16-17,23-24,30-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 VXNSUGHXYUJKAG-OFRDJWLHSA-N 50270940 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-2-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL507807 IgG receptor FcRn large subunit p51 Homo sapiens 6200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270940&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585820 104115983 CHEMBL507807 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415743 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnn[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H99N19O16S2/c1-38(2)28-52(63(99)80-49(31-42-22-24-44(90)25-23-42)66(102)88-27-15-21-51(88)62(98)81-50(37-105)67(103)104)87(7)55(93)36-86(6)54(92)35-75-59(95)46(29-40-16-10-8-11-17-40)79-60(96)48(32-43-33-76-85-84-43)77-53(91)34-74-64(100)56(39(3)89)82-65(101)57(69(4,5)106)83-61(97)47(30-41-18-12-9-13-19-41)78-58(94)45(70)20-14-26-73-68(71)72/h8-13,16-19,22-25,33,38-39,45-52,56-57,89-90,105-106H,14-15,20-21,26-32,34-37,70H2,1-7H3,(H,74,100)(H,75,95)(H,77,91)(H,78,94)(H,79,96)(H,80,99)(H,81,98)(H,82,101)(H,83,97)(H,103,104)(H4,71,72,73)(H,76,84,85)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 SIPWBDDMNAUTNG-SJGHIIINSA-N 50270939 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-1,2,3-triazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL505609 IgG receptor FcRn large subunit p51 Homo sapiens 5700 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270939&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585819 104115982 CHEMBL505609 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415744 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1csc[n+]1C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(N)=O InChI=1S/C71H102N18O15S3/c1-40(2)29-54(66(101)82-51(32-44-23-25-46(91)26-24-44)69(104)89-28-16-22-53(89)65(100)83-52(37-105)60(73)95)88(8)57(94)36-86(6)56(93)35-78-62(97)48(30-42-17-11-9-12-18-42)81-63(98)50(33-45-38-107-39-87(45)7)79-55(92)34-77-67(102)58(41(3)90)84-68(103)59(71(4,5)106)85-64(99)49(31-43-19-13-10-14-20-43)80-61(96)47(72)21-15-27-76-70(74)75/h9-14,17-20,23-26,38-41,47-54,58-59,90H,15-16,21-22,27-37,72H2,1-8H3,(H17-,73,74,75,76,77,78,79,80,81,82,83,84,85,91,92,95,96,97,98,99,100,101,102,103,105,106)/p+1/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 UUUMCMHCHPLAPZ-PMHNZZKJSA-O 50270938 4-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-2-{[(1S)-1-({[({[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}pyrrolidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl}-3-methylbutyl](methyl)carbamoyl}methyl)(methyl)carbamoyl]methyl}carbamoyl)-2-phenylethyl]carbamoyl}ethyl]-3-methyl-1,3-thiazol-3-ium::CHEMBL506195 IgG receptor FcRn large subunit p51 Homo sapiens 2400 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270938&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585818 104115981 CHEMBL506195 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415745 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cscn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H99N17O16S3/c1-39(2)28-53(64(98)81-50(31-43-22-24-45(89)25-23-43)67(101)87-27-15-21-52(87)63(97)82-51(36-104)68(102)103)86(7)56(92)35-85(6)55(91)34-76-60(94)47(29-41-16-10-8-11-17-41)80-61(95)49(32-44-37-106-38-77-44)78-54(90)33-75-65(99)57(40(3)88)83-66(100)58(70(4,5)105)84-62(96)48(30-42-18-12-9-13-19-42)79-59(93)46(71)20-14-26-74-69(72)73/h8-13,16-19,22-25,37-40,46-53,57-58,88-89,104-105H,14-15,20-21,26-36,71H2,1-7H3,(H,75,99)(H,76,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,72,73,74)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 GYWQUYXIOMIUSN-SCOIVGQKSA-N 50270937 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1,3-thiazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526373 IgG receptor FcRn large subunit p51 Homo sapiens 1600 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270937&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585817 104115980 CHEMBL526373 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415746 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C67H98N16O16S2/c1-37(2)29-50(61(94)77-47(32-42-23-25-43(85)26-24-42)64(97)83-28-16-22-49(83)60(93)78-48(36-100)65(98)99)82(8)53(88)35-81(7)52(87)34-73-58(91)45(30-40-17-11-9-12-18-40)75-56(89)38(3)74-51(86)33-72-62(95)54(39(4)84)79-63(96)55(67(5,6)101)80-59(92)46(31-41-19-13-10-14-20-41)76-57(90)44(68)21-15-27-71-66(69)70/h9-14,17-20,23-26,37-39,44-50,54-55,84-85,100-101H,15-16,21-22,27-36,68H2,1-8H3,(H,72,95)(H,73,91)(H,74,86)(H,75,89)(H,76,90)(H,77,94)(H,78,93)(H,79,96)(H,80,92)(H,98,99)(H4,69,70,71)/t38-,39+,44-,45-,46-,47-,48-,49-,50-,54-,55+/m0/s1 PLTHUPZHFFCLIW-SFICEKSFSA-N 50270953 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525232 IgG receptor FcRn large subunit p51 Homo sapiens 9900 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270953&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585833 104115996 CHEMBL525232 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415747 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H102N16O16S2/c1-42(2)33-56(67(100)83-53(37-47-27-29-48(91)30-28-47)70(103)89-32-18-26-55(89)66(99)84-54(41-106)71(104)105)88(7)59(94)40-87(6)58(93)39-79-63(96)50(34-44-19-11-8-12-20-44)82-64(97)51(35-45-21-13-9-14-22-45)80-57(92)38-78-68(101)60(43(3)90)85-69(102)61(73(4,5)107)86-65(98)52(36-46-23-15-10-16-24-46)81-62(95)49(74)25-17-31-77-72(75)76/h8-16,19-24,27-30,42-43,49-56,60-61,90-91,106-107H,17-18,25-26,31-41,74H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,75,76,77)/t43-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 XPNACTKSNQJUKY-IQKMKRTQSA-N 50270952 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-phenylpropanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524718 IgG receptor FcRn large subunit p51 Homo sapiens 3300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270952&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585832 104115995 CHEMBL524718 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415748 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCNCC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-25,41-42,46,48-55,59-60,76,90-91,106-107H,14-15,20-21,26-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 BMLIWXUJOHYWPK-OFRDJWLHSA-N 50270951 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525431 IgG receptor FcRn large subunit p51 Homo sapiens 5200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270951&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585831 104115994 CHEMBL525431 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415749 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCNC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-13,17-20,24-27,41-42,46,48-55,59-60,76,90-91,106-107H,14-16,21-23,28-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,46?,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 SDEOUMVKASFBFG-SQUBLMHESA-N 50270950 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526499 IgG receptor FcRn large subunit p51 Homo sapiens 660 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270950&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585830 104115993 CHEMBL526499 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415750 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cc[nH]c1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H101N17O16S2/c1-40(2)30-54(65(99)82-51(33-44-22-24-46(90)25-23-44)68(102)88-29-15-21-53(88)64(98)83-52(39-105)69(103)104)87(7)57(93)38-86(6)56(92)37-78-61(95)48(31-42-16-10-8-11-17-42)81-62(96)49(34-45-26-28-75-35-45)79-55(91)36-77-66(100)58(41(3)89)84-67(101)59(71(4,5)106)85-63(97)50(32-43-18-12-9-13-19-43)80-60(94)47(72)20-14-27-76-70(73)74/h8-13,16-19,22-26,28,35,40-41,47-54,58-59,75,89-90,105-106H,14-15,20-21,27,29-34,36-39,72H2,1-7H3,(H,77,100)(H,78,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,73,74,76)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 NGAVDNSZVZELRG-PMHNZZKJSA-N 50270949 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-pyrrol-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL510720 IgG receptor FcRn large subunit p51 Homo sapiens 8400 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270949&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585829 104115992 CHEMBL510720 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415751 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 VDTFZUDODVYEAQ-GAIGFMGPSA-N 50270948 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-aminophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504837 IgG receptor FcRn large subunit p51 Homo sapiens 220 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270948&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585828 104115991 CHEMBL504837 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415752 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 LTJSIONUIYPBNM-GAIGFMGPSA-N 50270947 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-carbamimidamidophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504003 IgG receptor FcRn large subunit p51 Homo sapiens 74 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270947&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935284 104115990 CHEMBL504003 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415753 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N19O16S2/c1-39(2)31-52(63(100)83-49(34-43-24-26-44(91)27-25-43)66(103)89-30-16-23-51(89)62(99)84-50(38-106)67(104)105)88(7)55(94)37-87(6)54(93)36-79-59(96)47(32-41-17-10-8-11-18-41)82-60(97)46(22-15-29-77-69(74)75)80-53(92)35-78-64(101)56(40(3)90)85-65(102)57(70(4,5)107)86-61(98)48(33-42-19-12-9-13-20-42)81-58(95)45(71)21-14-28-76-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,90-91,106-107H,14-16,21-23,28-38,71H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,72,73,76)(H4,74,75,77)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 UYTJXNOKSSRZIA-ZTUWISBESA-N 50270946 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL509335 IgG receptor FcRn large subunit p51 Homo sapiens 500 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270946&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585826 104115989 CHEMBL509335 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415754 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N17O16S2/c1-40(2)32-53(64(98)81-50(35-44-25-27-45(89)28-26-44)67(101)87-31-17-24-52(87)63(97)82-51(39-104)68(102)103)86(7)56(92)38-85(6)55(91)37-77-60(94)48(33-42-18-10-8-11-19-42)80-61(95)47(23-14-15-29-71)78-54(90)36-76-65(99)57(41(3)88)83-66(100)58(70(4,5)105)84-62(96)49(34-43-20-12-9-13-21-43)79-59(93)46(72)22-16-30-75-69(73)74/h8-13,18-21,25-28,40-41,46-53,57-58,88-89,104-105H,14-17,22-24,29-39,71-72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 ZWGRTIDGLKIEMS-XMFJQSQOSA-N 50270945 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-6-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}hexanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524297 IgG receptor FcRn large subunit p51 Homo sapiens 1300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270945&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585825 104115988 CHEMBL524297 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415755 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H103N17O16S2/c1-39(2)31-52(63(97)80-49(34-43-24-26-44(88)27-25-43)66(100)86-30-16-23-51(86)62(96)81-50(38-103)67(101)102)85(7)55(91)37-84(6)54(90)36-76-59(93)47(32-41-17-10-8-11-18-41)79-60(94)46(22-14-28-70)77-53(89)35-75-64(98)56(40(3)87)82-65(99)57(69(4,5)104)83-61(95)48(33-42-19-12-9-13-20-42)78-58(92)45(71)21-15-29-74-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,87-88,103-104H,14-16,21-23,28-38,70-71H2,1-7H3,(H,75,98)(H,76,93)(H,77,89)(H,78,92)(H,79,94)(H,80,97)(H,81,96)(H,82,99)(H,83,95)(H,101,102)(H4,72,73,74)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 BSBUVESIVQAPEC-ZTUWISBESA-N 50270944 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-5-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}pentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504336 IgG receptor FcRn large subunit p51 Homo sapiens 1300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270944&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585824 104115987 CHEMBL504336 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415756 CC(C)C[C@H](NC(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H102N18O16S2/c1-40(2)30-49(61(96)85-53(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-55(90)65(100)86-54(38-107)70(105)106)81-57(94)37-89-28-13-12-21-48(68(89)103)82-62(97)50(31-42-16-8-6-9-17-42)84-63(98)52(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)87-67(102)59(72(4,5)108)88-64(99)51(32-43-18-10-7-11-19-43)83-60(95)47(73)20-14-27-77-71(74)75/h6-11,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,12-15,20-22,27-34,36-38,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,94)(H,82,97)(H,83,95)(H,84,98)(H,85,96)(H,86,100)(H,87,102)(H,88,99)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1 WYKYRXRDTYKWKS-MDOMHRAVSA-N 50270961 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL486090 IgG receptor FcRn large subunit p51 Homo sapiens 640 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270961&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585841 104116004 CHEMBL486090 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415757 CC(C)C[C@H](NC(=O)CN1CCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,57+,58+/m1/s1 YNUAWVMAHNXUNN-FTNKEKBBSA-N 50270960 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3S)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL499749 IgG receptor FcRn large subunit p51 Homo sapiens 7200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270960&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585840 104116003 CHEMBL499749 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415758 CC(C)C[C@H](NC(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47-,48+,49+,50+,51+,52+,53+,54+,57+,58-/m1/s1 YNUAWVMAHNXUNN-LEXWUHMVSA-N 50270959 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524887 IgG receptor FcRn large subunit p51 Homo sapiens 660 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270959&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585839 104116002 CHEMBL524887 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415759 CC(C)C[C@H](NC(=O)CN1CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H98N18O16S2/c1-38(2)28-47(59(94)83-51(31-42-20-22-44(90)23-21-42)67(102)88-26-13-19-53(88)63(98)84-52(36-105)68(103)104)79-55(92)35-87-27-24-46(66(87)101)80-60(95)48(29-40-14-8-6-9-15-40)82-61(96)50(32-43-33-74-37-77-43)78-54(91)34-76-64(99)56(39(3)89)85-65(100)57(70(4,5)106)86-62(97)49(30-41-16-10-7-11-17-41)81-58(93)45(71)18-12-25-75-69(72)73/h6-11,14-17,20-23,33,37-39,45-53,56-57,89-90,105-106H,12-13,18-19,24-32,34-36,71H2,1-5H3,(H,74,77)(H,76,99)(H,78,91)(H,79,92)(H,80,95)(H,81,93)(H,82,96)(H,83,94)(H,84,98)(H,85,100)(H,86,97)(H,103,104)(H4,72,73,75)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,56+,57-/m1/s1 MRHLBESBKBPMGO-QAAZBOMKSA-N 50270958 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopyrrolidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526381 IgG receptor FcRn large subunit p51 Homo sapiens 2300 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270958&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585838 104116001 CHEMBL526381 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415760 CC(C)C[C@H](NC(=O)Cc1cccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)c1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H97N17O15S2/c1-40(2)29-50(63(96)85-54(33-44-23-25-48(91)26-24-44)69(102)89-28-14-22-56(89)66(99)86-55(38-105)70(103)104)81-57(92)34-45-19-12-20-46(30-45)80-62(95)51(31-42-15-8-6-9-16-42)84-64(97)53(35-47-36-76-39-79-47)82-58(93)37-78-67(100)59(41(3)90)87-68(101)60(72(4,5)106)88-65(98)52(32-43-17-10-7-11-18-43)83-61(94)49(73)21-13-27-77-71(74)75/h6-12,15-20,23-26,30,36,39-41,49-56,59-60,90-91,105-106H,13-14,21-22,27-29,31-35,37-38,73H2,1-5H3,(H,76,79)(H,78,100)(H,80,95)(H,81,92)(H,82,93)(H,83,94)(H,84,97)(H,85,96)(H,86,99)(H,87,101)(H,88,98)(H,103,104)(H4,74,75,77)/t41-,49+,50+,51+,52+,53+,54+,55+,56+,59+,60-/m1/s1 LTQRRZMXMVNGAT-YNESVYEZSA-N 50270957 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]phenyl}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504543 IgG receptor FcRn large subunit p51 Homo sapiens 14000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270957&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585837 104116000 CHEMBL504543 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415761 CC(C)C[C@H](NC(=O)Cc1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H97N17O15S2/c1-40(2)30-50(63(96)85-54(33-44-22-26-48(91)27-23-44)69(102)89-29-13-19-56(89)66(99)86-55(38-105)70(103)104)81-57(92)34-45-20-24-46(25-21-45)80-62(95)51(31-42-14-8-6-9-15-42)84-64(97)53(35-47-36-76-39-79-47)82-58(93)37-78-67(100)59(41(3)90)87-68(101)60(72(4,5)106)88-65(98)52(32-43-16-10-7-11-17-43)83-61(94)49(73)18-12-28-77-71(74)75/h6-11,14-17,20-27,36,39-41,49-56,59-60,90-91,105-106H,12-13,18-19,28-35,37-38,73H2,1-5H3,(H,76,79)(H,78,100)(H,80,95)(H,81,92)(H,82,93)(H,83,94)(H,84,97)(H,85,96)(H,86,99)(H,87,101)(H,88,98)(H,103,104)(H4,74,75,77)/t41-,49+,50+,51+,52+,53+,54+,55+,56+,59+,60-/m1/s1 NDAIQYAGFBBXJJ-YNESVYEZSA-N 50270956 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{4-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]phenyl}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL508454 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270956&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585836 104115999 CHEMBL508454 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415762 CC(C)C[C@H](NC(=O)c1ccc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H97N17O15S2/c1-40(2)30-50(63(96)85-54(33-44-22-26-48(91)27-23-44)69(102)89-29-13-19-56(89)66(99)86-55(38-105)70(103)104)82-60(93)46-24-20-45(21-25-46)35-78-62(95)51(31-42-14-8-6-9-15-42)84-64(97)53(34-47-36-76-39-80-47)81-57(92)37-79-67(100)58(41(3)90)87-68(101)59(72(4,5)106)88-65(98)52(32-43-16-10-7-11-17-43)83-61(94)49(73)18-12-28-77-71(74)75/h6-11,14-17,20-27,36,39-41,49-56,58-59,90-91,105-106H,12-13,18-19,28-35,37-38,73H2,1-5H3,(H,76,80)(H,78,95)(H,79,100)(H,81,92)(H,82,93)(H,83,94)(H,84,97)(H,85,96)(H,86,99)(H,87,101)(H,88,98)(H,103,104)(H4,74,75,77)/t41-,49+,50+,51+,52+,53+,54+,55+,56+,58+,59-/m1/s1 NHFOGEAKXWFGBP-JEBYBPICSA-N 50270954 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(4-{[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]methyl}phenyl)formamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL506848 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270954&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585834 104115997 CHEMBL506848 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415763 CC(C)C[C@H](NC(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C72H102N18O16/c1-40(2)31-51(62(96)86-55(34-46-24-26-48(92)27-25-46)70(104)90-30-16-23-56(90)66(100)80-42(5)71(105)106)82-58(94)38-89-29-14-13-22-50(69(89)103)83-63(97)52(32-44-17-9-7-10-18-44)85-64(98)54(35-47-36-76-39-79-47)81-57(93)37-78-67(101)60(43(6)91)88-68(102)59(41(3)4)87-65(99)53(33-45-19-11-8-12-20-45)84-61(95)49(73)21-15-28-77-72(74)75/h7-12,17-20,24-27,36,39-43,49-56,59-60,91-92H,13-16,21-23,28-35,37-38,73H2,1-6H3,(H,76,79)(H,78,101)(H,80,100)(H,81,93)(H,82,94)(H,83,97)(H,84,95)(H,85,98)(H,86,96)(H,87,99)(H,88,102)(H,105,106)(H4,74,75,77)/t42-,43+,49-,50+,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 BYQYPTXOMZUXOR-OYXZUBOTSA-N 50270986 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL500441 IgG receptor FcRn large subunit p51 Homo sapiens 2300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270986&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585866 104116029 CHEMBL500441 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415764 CC(C)C[C@H](NC(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C71H100N18O16/c1-39(2)30-50(61(95)85-54(33-45-23-25-47(91)26-24-45)69(103)89-29-15-22-55(89)65(99)79-41(5)70(104)105)81-57(93)37-88-28-14-21-49(68(88)102)82-62(96)51(31-43-16-9-7-10-17-43)84-63(97)53(34-46-35-75-38-78-46)80-56(92)36-77-66(100)59(42(6)90)87-67(101)58(40(3)4)86-64(98)52(32-44-18-11-8-12-19-44)83-60(94)48(72)20-13-27-76-71(73)74/h7-12,16-19,23-26,35,38-42,48-55,58-59,90-91H,13-15,20-22,27-34,36-37,72H2,1-6H3,(H,75,78)(H,77,100)(H,79,99)(H,80,92)(H,81,93)(H,82,96)(H,83,94)(H,84,97)(H,85,95)(H,86,98)(H,87,101)(H,104,105)(H4,73,74,76)/t41-,42+,48-,49+,50-,51-,52-,53-,54-,55-,58-,59-/m0/s1 CHCLMWAHFABHFZ-KEACGAIKSA-N 50270985 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL508902 IgG receptor FcRn large subunit p51 Homo sapiens 3300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270985&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585865 104116028 CHEMBL508902 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415765 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C70H100N18O16/c1-39(2)29-54(65(99)83-52(32-45-23-25-47(90)26-24-45)68(102)88-28-16-22-53(88)64(98)79-41(5)69(103)104)87(8)57(93)37-86(7)56(92)36-77-61(95)49(30-43-17-11-9-12-18-43)82-62(96)51(33-46-34-74-38-78-46)80-55(91)35-76-66(100)59(42(6)89)85-67(101)58(40(3)4)84-63(97)50(31-44-19-13-10-14-20-44)81-60(94)48(71)21-15-27-75-70(72)73/h9-14,17-20,23-26,34,38-42,48-54,58-59,89-90H,15-16,21-22,27-33,35-37,71H2,1-8H3,(H,74,78)(H,76,100)(H,77,95)(H,79,98)(H,80,91)(H,81,94)(H,82,96)(H,83,99)(H,84,97)(H,85,101)(H,103,104)(H4,72,73,75)/t41-,42+,48-,49-,50-,51-,52-,53-,54-,58-,59-/m0/s1 GBPJUAXDJHWEIX-QCRZSQONSA-N 50270984 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL499121 IgG receptor FcRn large subunit p51 Homo sapiens 1850 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270984&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585864 104116027 CHEMBL499121 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415766 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O24/c1-43(2)29-52(73(121)101-57(32-47-20-22-49(110)23-21-47)80(128)106-28-11-18-60(106)78(126)103-58(40-107)76(124)100-56(34-63(85)112)71(119)93-39-67(116)105-27-12-19-61(105)81(129)130)95-65(114)37-90-64(113)36-91-70(118)53(30-45-13-6-4-7-14-45)98-75(123)55(33-48-35-88-42-94-48)96-66(115)38-92-79(127)68(44(3)109)104-77(125)59(41-108)102-74(122)54(31-46-15-8-5-9-16-46)99-72(120)51(17-10-26-89-82(86)87)97-69(117)50(83)24-25-62(84)111/h4-9,13-16,20-23,35,42-44,50-61,68,107-110H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,111)(H2,85,112)(H,88,94)(H,90,113)(H,91,118)(H,92,127)(H,93,119)(H,95,114)(H,96,115)(H,97,117)(H,98,123)(H,99,120)(H,100,124)(H,101,121)(H,102,122)(H,103,126)(H,104,125)(H,129,130)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 AUSBKGPHCIVTPH-YNALCKGOSA-N 50270983 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506645 IgG receptor FcRn large subunit p51 Homo sapiens 230000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270983&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935301 104116026 CHEMBL506645 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415767 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H125N25O24/c1-47(2)35-58(80(129)109-63(38-51-23-25-53(114)26-24-51)85(134)112-34-13-21-64(112)83(132)105-57(28-30-72(121)122)78(127)108-62(40-67(91)116)76(125)99-45-71(120)111-33-14-22-65(111)86(135)136)101-69(118)43-96-68(117)42-97-75(124)59(36-49-15-6-4-7-16-49)106-82(131)61(39-52-41-94-46-100-52)102-70(119)44-98-84(133)73(48(3)113)110-79(128)55(19-10-11-31-88)104-81(130)60(37-50-17-8-5-9-18-50)107-77(126)56(20-12-32-95-87(92)93)103-74(123)54(89)27-29-66(90)115/h4-9,15-18,23-26,41,46-48,54-65,73,113-114H,10-14,19-22,27-40,42-45,88-89H2,1-3H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,124)(H,98,133)(H,99,125)(H,101,118)(H,102,119)(H,103,123)(H,104,130)(H,105,132)(H,106,131)(H,107,126)(H,108,127)(H,109,129)(H,110,128)(H,121,122)(H,135,136)(H4,92,93,95)/t48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,73+/m1/s1 ZLPUHJRLIMHCEO-YNSMZBETSA-N 50270982 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]hexanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL510066 IgG receptor FcRn large subunit p51 Homo sapiens 1200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270982&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935300 104116025 CHEMBL510066 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415768 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)33-56(78(127)107-61(36-49-20-22-51(112)23-21-49)83(132)110-32-11-18-62(110)81(130)103-54(25-27-70(119)120)76(125)106-60(38-65(89)114)74(123)97-43-69(118)109-31-12-19-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)57(34-47-13-6-4-7-14-47)104-80(129)59(37-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-77(126)55(28-29-86)102-79(128)58(35-48-15-8-5-9-16-48)105-75(124)53(17-10-30-93-85(90)91)101-72(121)52(87)24-26-64(88)113/h4-9,13-16,20-23,39,44-46,52-63,71,111-112H,10-12,17-19,24-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,128)(H,103,130)(H,104,129)(H,105,124)(H,106,125)(H,107,127)(H,108,126)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 AWRLMOAKWKXHJL-QZSPZITESA-N 50270980 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-4-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]butanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508398 IgG receptor FcRn large subunit p51 Homo sapiens 4800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270980&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935298 104116023 CHEMBL508398 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415769 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)33-56(78(127)108-62(36-50-23-25-52(113)26-24-50)84(133)111-32-13-21-63(111)82(131)107-61(39-71(120)121)81(130)106-60(38-66(90)115)75(124)98-44-70(119)110-31-14-22-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)57(34-48-15-6-4-7-16-48)104-80(129)59(37-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-77(126)54(19-10-11-29-87)103-79(128)58(35-49-17-8-5-9-18-49)105-76(125)55(20-12-30-94-86(91)92)102-73(122)53(88)27-28-65(89)114/h4-9,15-18,23-26,40,45-47,53-64,72,112-113H,10-14,19-22,27-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,128)(H,104,129)(H,105,125)(H,106,130)(H,107,131)(H,108,127)(H,109,126)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 BMVSGWJINAYAQP-JQYWQRDCSA-N 50270978 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]hexanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL527072 IgG receptor FcRn large subunit p51 Homo sapiens 10000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270978&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935296 104116021 CHEMBL527072 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415770 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)106-60(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)105-59(37-69(118)119)79(128)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-75(124)53(26-27-85)101-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-25-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,126)(H,102,127)(H,103,123)(H,104,128)(H,105,129)(H,106,125)(H,107,124)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 YLGGPWMPBOKPRB-AZARTFGISA-N 50270976 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-4-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]butanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503191 IgG receptor FcRn large subunit p51 Homo sapiens 8400 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270976&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935294 104116019 CHEMBL503191 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415771 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H125N25O24/c1-47(2)35-58(80(129)109-63(38-51-23-25-53(114)26-24-51)85(134)112-34-13-21-64(112)83(132)105-55(19-10-11-31-88)77(126)108-62(40-67(91)116)76(125)99-45-71(120)111-33-14-22-65(111)86(135)136)101-69(118)43-96-68(117)42-97-75(124)59(36-49-15-6-4-7-16-49)106-82(131)61(39-52-41-94-46-100-52)102-70(119)44-98-84(133)73(48(3)113)110-79(128)57(28-30-72(121)122)104-81(130)60(37-50-17-8-5-9-18-50)107-78(127)56(20-12-32-95-87(92)93)103-74(123)54(89)27-29-66(90)115/h4-9,15-18,23-26,41,46-48,54-65,73,113-114H,10-14,19-22,27-40,42-45,88-89H2,1-3H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,124)(H,98,133)(H,99,125)(H,101,118)(H,102,119)(H,103,123)(H,104,130)(H,105,132)(H,106,131)(H,107,127)(H,108,126)(H,109,129)(H,110,128)(H,121,122)(H,135,136)(H4,92,93,95)/t48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,73+/m1/s1 ACHPFSSODZFULV-YNSMZBETSA-N 50270974 (2S)-1-{2-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508704 IgG receptor FcRn large subunit p51 Homo sapiens 27000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270974&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935292 104116017 CHEMBL508704 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415772 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)34-57(79(128)108-62(37-50-22-24-52(113)25-23-50)84(133)111-33-12-20-63(111)82(131)104-54(18-10-30-87)76(125)107-61(39-66(90)115)75(124)98-44-70(119)110-32-13-21-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)58(35-48-14-6-4-7-15-48)105-81(130)60(38-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-78(127)56(27-29-71(120)121)103-80(129)59(36-49-16-8-5-9-17-49)106-77(126)55(19-11-31-94-86(91)92)102-73(122)53(88)26-28-65(89)114/h4-9,14-17,22-25,40,45-47,53-64,72,112-113H,10-13,18-21,26-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,129)(H,104,131)(H,105,130)(H,106,126)(H,107,125)(H,108,128)(H,109,127)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 QYCUXBLVBNBTGZ-JQYWQRDCSA-N 50270973 (2S)-1-{2-[(2S)-2-[(2S)-5-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501283 IgG receptor FcRn large subunit p51 Homo sapiens 15000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270973&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935291 104116016 CHEMBL501283 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415773 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)33-56(78(127)107-61(36-49-20-22-51(112)23-21-49)83(132)110-32-11-18-62(110)81(130)103-55(28-29-86)76(125)106-60(38-65(89)114)74(123)97-43-69(118)109-31-12-19-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)57(34-47-13-6-4-7-14-47)104-80(129)59(37-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-77(126)54(25-27-70(119)120)102-79(128)58(35-48-15-8-5-9-16-48)105-75(124)53(17-10-30-93-85(90)91)101-72(121)52(87)24-26-64(88)113/h4-9,13-16,20-23,39,44-46,52-63,71,111-112H,10-12,17-19,24-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,128)(H,103,130)(H,104,129)(H,105,124)(H,106,125)(H,107,127)(H,108,126)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 DNGHQZAJUQMBNF-QZSPZITESA-N 50270972 (2S)-1-{2-[(2S)-2-[(2S)-4-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}butanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503205 IgG receptor FcRn large subunit p51 Homo sapiens 22000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270972&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935290 104116015 CHEMBL503205 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415774 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)105-59(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)106-60(37-85)79(128)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-75(124)53(25-27-69(118)119)101-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-26-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,126)(H,102,127)(H,103,123)(H,104,128)(H,105,125)(H,106,129)(H,107,124)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 KBIMFOIIGNJKLI-AZARTFGISA-N 50270971 (2S)-1-{2-[(2S)-2-[(2S)-3-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508491 IgG receptor FcRn large subunit p51 Homo sapiens 9600 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270971&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935289 104116014 CHEMBL508491 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415775 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)33-56(78(127)108-62(36-50-23-25-52(113)26-24-50)84(133)111-32-13-21-63(111)82(131)103-54(19-10-11-29-87)76(125)106-60(38-66(90)115)75(124)98-44-70(119)110-31-14-22-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)57(34-48-15-6-4-7-16-48)104-80(129)59(37-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-81(130)61(39-71(120)121)107-79(128)58(35-49-17-8-5-9-18-49)105-77(126)55(20-12-30-94-86(91)92)102-73(122)53(88)27-28-65(89)114/h4-9,15-18,23-26,40,45-47,53-64,72,112-113H,10-14,19-22,27-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,131)(H,104,129)(H,105,126)(H,106,125)(H,107,128)(H,108,127)(H,109,130)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 LWGWSFVMTWVAKK-JQYWQRDCSA-N 50270970 (2S)-1-{2-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525624 IgG receptor FcRn large subunit p51 Homo sapiens 1200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270970&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935288 104116013 CHEMBL525624 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415776 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)32-55(77(126)107-61(35-49-22-24-51(112)25-23-49)83(132)110-31-12-20-62(110)81(130)102-53(18-10-28-86)75(124)105-59(37-65(89)114)74(123)97-43-69(118)109-30-13-21-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)56(33-47-14-6-4-7-15-47)103-79(128)58(36-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-80(129)60(38-70(119)120)106-78(127)57(34-48-16-8-5-9-17-48)104-76(125)54(19-11-29-93-85(90)91)101-72(121)52(87)26-27-64(88)113/h4-9,14-17,22-25,39,44-46,52-63,71,111-112H,10-13,18-21,26-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,130)(H,103,128)(H,104,125)(H,105,124)(H,106,127)(H,107,126)(H,108,129)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 CVZXHGRAETXFEG-QZSPZITESA-N 50270969 (2S)-1-{2-[(2S)-2-[(2S)-5-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL450322 IgG receptor FcRn large subunit p51 Homo sapiens 2700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270969&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935287 104116012 CHEMBL450322 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415777 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)106-60(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)101-53(26-27-85)75(124)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-79(128)59(37-69(118)119)105-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-25-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,129)(H,102,127)(H,103,123)(H,104,124)(H,105,126)(H,106,125)(H,107,128)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 JSQQGMJNNNMSPR-AZARTFGISA-N 50270968 (2S)-1-{2-[(2S)-2-[(2S)-4-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}butanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL526130 IgG receptor FcRn large subunit p51 Homo sapiens 17000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270968&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935286 104116011 CHEMBL526130 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415778 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H117N25O24/c1-43(2)29-52(74(123)104-58(32-47-20-22-49(110)23-21-47)81(130)108-28-11-18-60(108)79(128)105-59(36-84)78(127)102-56(34-63(87)112)72(121)95-41-67(116)107-27-12-19-61(107)82(131)132)97-65(114)39-92-64(113)38-93-71(120)53(30-45-13-6-4-7-14-45)100-76(125)55(33-48-37-90-42-96-48)98-66(115)40-94-80(129)69(44(3)109)106-77(126)57(35-68(117)118)103-75(124)54(31-46-15-8-5-9-16-46)101-73(122)51(17-10-26-91-83(88)89)99-70(119)50(85)24-25-62(86)111/h4-9,13-16,20-23,37,42-44,50-61,69,109-110H,10-12,17-19,24-36,38-41,84-85H2,1-3H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,120)(H,94,129)(H,95,121)(H,97,114)(H,98,115)(H,99,119)(H,100,125)(H,101,122)(H,102,127)(H,103,124)(H,104,123)(H,105,128)(H,106,126)(H,117,118)(H,131,132)(H4,88,89,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,69+/m1/s1 IWVVFRAGJKNOTJ-YHTHZICESA-N 50270967 (2S)-1-{2-[(2S)-2-[(2S)-3-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506740 IgG receptor FcRn large subunit p51 Homo sapiens 4500 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270967&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935285 104116010 CHEMBL506740 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415779 CC(C)C[C@H](N(C)C(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H104N18O16S2/c1-41(2)31-56(66(101)85-53(34-45-24-26-47(93)27-25-45)70(105)91-30-16-23-55(91)65(100)86-54(39-108)71(106)107)89(6)58(95)38-90-29-14-13-22-49(69(90)104)82-62(97)50(32-43-17-9-7-10-18-43)84-63(98)52(35-46-36-77-40-80-46)81-57(94)37-79-67(102)59(42(3)92)87-68(103)60(73(4,5)109)88-64(99)51(33-44-19-11-8-12-20-44)83-61(96)48(74)21-15-28-78-72(75)76/h7-12,17-20,24-27,36,40-42,48-56,59-60,92-93,108-109H,13-16,21-23,28-35,37-39,74H2,1-6H3,(H,77,80)(H,79,102)(H,81,94)(H,82,97)(H,83,96)(H,84,98)(H,85,101)(H,86,100)(H,87,103)(H,88,99)(H,106,107)(H4,75,76,78)/t42-,48+,49-,50+,51+,52+,53+,54+,55+,56+,59+,60+/m1/s1 FWVGXRFGTDNWQB-NBXYRGRJSA-N 50270966 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]-N-methylacetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526174 IgG receptor FcRn large subunit p51 Homo sapiens 44 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270966&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585846 104116009 CHEMBL526174 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415780 CC(C)C[C@H](N(C)C(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H102N18O16S2/c1-40(2)30-55(65(100)84-52(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-54(90)64(99)85-53(38-107)70(105)106)88(6)57(94)37-89-28-14-21-48(68(89)103)81-61(96)49(31-42-16-9-7-10-17-42)83-62(97)51(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)86-67(102)59(72(4,5)108)87-63(98)50(32-43-18-11-8-12-19-43)82-60(95)47(73)20-13-27-77-71(74)75/h7-12,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,13-15,20-22,27-34,36-38,73H2,1-6H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,95)(H,83,97)(H,84,100)(H,85,99)(H,86,102)(H,87,98)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1 ISEDOUIWHCJEGY-MDOMHRAVSA-N 50270965 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]-N-methylacetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL500475 IgG receptor FcRn large subunit p51 Homo sapiens 43 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270965&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585845 104116008 CHEMBL500475 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415781 CC(C)C[C@H](NC(=O)[C@H]1CS[C@@H]2CC[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H100N18O16S3/c1-38(2)28-47(60(95)85-51(31-42-20-22-44(92)23-21-42)68(103)89-27-13-19-53(89)64(99)86-52(35-107)70(105)106)84-65(100)54-36-109-56-25-24-46(69(104)90(54)56)81-61(96)48(29-40-14-8-6-9-15-40)83-62(97)50(32-43-33-76-37-79-43)80-55(93)34-78-66(101)57(39(3)91)87-67(102)58(72(4,5)108)88-63(98)49(30-41-16-10-7-11-17-41)82-59(94)45(73)18-12-26-77-71(74)75/h6-11,14-17,20-23,33,37-39,45-54,56-58,91-92,107-108H,12-13,18-19,24-32,34-36,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,100)(H,85,95)(H,86,99)(H,87,102)(H,88,98)(H,105,106)(H4,74,75,77)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,54-,56-,57+,58+/m1/s1 ORMBSNDOGYKGRZ-PLGXUIQYSA-N 50270964 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R,8aR)-6-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-5-oxo-hexahydro-2H-pyrido[2,1-b][1,3]thiazol-3-yl]formamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525583 IgG receptor FcRn large subunit p51 Homo sapiens 320 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270964&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585844 104116007 CHEMBL525583 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415782 CC(C)C[C@H](NC(=O)[C@H]1CSC2C[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H98N18O16S3/c1-37(2)26-45(59(94)83-49(29-41-20-22-43(91)23-21-41)67(102)88-25-13-19-52(88)63(98)85-51(34-106)69(104)105)82-64(99)53-35-108-55-31-50(68(103)89(53)55)84-60(95)46(27-39-14-8-6-9-15-39)81-61(96)48(30-42-32-75-36-78-42)79-54(92)33-77-65(100)56(38(3)90)86-66(101)57(71(4,5)107)87-62(97)47(28-40-16-10-7-11-17-40)80-58(93)44(72)18-12-24-76-70(73)74/h6-11,14-17,20-23,32,36-38,44-53,55-57,90-91,106-107H,12-13,18-19,24-31,33-35,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,99)(H,83,94)(H,84,95)(H,85,98)(H,86,101)(H,87,97)(H,104,105)(H4,73,74,76)/t38-,44+,45+,46+,47+,48+,49+,50-,51+,52+,53-,55?,56+,57+/m1/s1 FEZKMFDXZVPPPA-VIMAYOAJSA-N 50270962 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R)-6-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazol-3-yl]formamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504539 IgG receptor FcRn large subunit p51 Homo sapiens 990 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270962&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585842 104116005 CHEMBL504539 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415783 CC(C)C[C@H](NC(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H102N18O16S2/c1-40(2)30-49(61(96)85-53(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-55(90)65(100)86-54(38-107)70(105)106)81-57(94)37-89-28-13-12-21-48(68(89)103)82-62(97)50(31-42-16-8-6-9-17-42)84-63(98)52(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)87-67(102)59(72(4,5)108)88-64(99)51(32-43-18-10-7-11-19-43)83-60(95)47(73)20-14-27-77-71(74)75/h6-11,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,12-15,20-22,27-34,36-38,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,94)(H,82,97)(H,83,95)(H,84,98)(H,85,96)(H,86,100)(H,87,102)(H,88,99)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1 WYKYRXRDTYKWKS-MDOMHRAVSA-N 50270961 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL486090 IgG receptor FcRn large subunit p51 Homo sapiens 103 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270961&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585841 104116004 CHEMBL486090 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415784 CC(C)C[C@H](NC(=O)CN1CCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,57+,58+/m1/s1 YNUAWVMAHNXUNN-FTNKEKBBSA-N 50270960 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3S)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL499749 IgG receptor FcRn large subunit p51 Homo sapiens 670 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270960&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585840 104116003 CHEMBL499749 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415785 CC(C)C[C@H](NC(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47-,48+,49+,50+,51+,52+,53+,54+,57+,58-/m1/s1 YNUAWVMAHNXUNN-LEXWUHMVSA-N 50270959 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524887 IgG receptor FcRn large subunit p51 Homo sapiens 160 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270959&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585839 104116002 CHEMBL524887 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415786 CC(C)C[C@H](NC(=O)CN1CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H98N18O16S2/c1-38(2)28-47(59(94)83-51(31-42-20-22-44(90)23-21-42)67(102)88-26-13-19-53(88)63(98)84-52(36-105)68(103)104)79-55(92)35-87-27-24-46(66(87)101)80-60(95)48(29-40-14-8-6-9-15-40)82-61(96)50(32-43-33-74-37-77-43)78-54(91)34-76-64(99)56(39(3)89)85-65(100)57(70(4,5)106)86-62(97)49(30-41-16-10-7-11-17-41)81-58(93)45(71)18-12-25-75-69(72)73/h6-11,14-17,20-23,33,37-39,45-53,56-57,89-90,105-106H,12-13,18-19,24-32,34-36,71H2,1-5H3,(H,74,77)(H,76,99)(H,78,91)(H,79,92)(H,80,95)(H,81,93)(H,82,96)(H,83,94)(H,84,98)(H,85,100)(H,86,97)(H,103,104)(H4,72,73,75)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,56+,57-/m1/s1 MRHLBESBKBPMGO-QAAZBOMKSA-N 50270958 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopyrrolidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526381 IgG receptor FcRn large subunit p51 Homo sapiens 280 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270958&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585838 104116001 CHEMBL526381 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415787 CC(C)C[C@H](NC(=O)c1cccc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)c1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H97N17O15S2/c1-40(2)29-50(63(96)85-54(33-44-23-25-48(91)26-24-44)69(102)89-28-14-22-56(89)66(99)86-55(38-105)70(103)104)82-60(93)46-20-12-19-45(30-46)35-78-62(95)51(31-42-15-8-6-9-16-42)84-64(97)53(34-47-36-76-39-80-47)81-57(92)37-79-67(100)58(41(3)90)87-68(101)59(72(4,5)106)88-65(98)52(32-43-17-10-7-11-18-43)83-61(94)49(73)21-13-27-77-71(74)75/h6-12,15-20,23-26,30,36,39-41,49-56,58-59,90-91,105-106H,13-14,21-22,27-29,31-35,37-38,73H2,1-5H3,(H,76,80)(H,78,95)(H,79,100)(H,81,92)(H,82,93)(H,83,94)(H,84,97)(H,85,96)(H,86,99)(H,87,101)(H,88,98)(H,103,104)(H4,74,75,77)/t41-,49+,50+,51+,52+,53+,54+,55+,56+,58+,59-/m1/s1 CSNCLACSJOSJAW-JEBYBPICSA-N 50270955 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(3-{[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]methyl}phenyl)formamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525088 IgG receptor FcRn large subunit p51 Homo sapiens 57000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270955&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585835 104115998 CHEMBL525088 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415788 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H100N18O16S2/c1-39(2)28-53(64(99)82-50(31-43-22-24-45(90)25-23-43)67(102)88-27-15-21-52(88)63(98)83-51(37-105)68(103)104)87(7)56(93)36-86(6)55(92)35-77-60(95)47(29-41-16-10-8-11-17-41)81-61(96)49(32-44-33-74-38-78-44)79-54(91)34-76-65(100)57(40(3)89)84-66(101)58(70(4,5)106)85-62(97)48(30-42-18-12-9-13-19-42)80-59(94)46(71)20-14-26-75-69(72)73/h8-13,16-19,22-25,33,38-40,46-53,57-58,89-90,105-106H,14-15,20-21,26-32,34-37,71H2,1-7H3,(H,74,78)(H,76,100)(H,77,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,72,73,75)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 AJONUWHGRIXLLX-SCOIVGQKSA-N 50270987 CHEMBL443697::SYN-1327 IgG receptor FcRn large subunit p51 Homo sapiens 570 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270987&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 25090771 104116030 CHEMBL443697 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415789 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H100N18O16S2/c1-39(2)28-53(64(99)82-50(31-43-22-24-45(90)25-23-43)67(102)88-27-15-21-52(88)63(98)83-51(37-105)68(103)104)87(7)56(93)36-86(6)55(92)35-77-60(95)47(29-41-16-10-8-11-17-41)81-61(96)49(32-44-33-74-38-78-44)79-54(91)34-76-65(100)57(40(3)89)84-66(101)58(70(4,5)106)85-62(97)48(30-42-18-12-9-13-19-42)80-59(94)46(71)20-14-26-75-69(72)73/h8-13,16-19,22-25,33,38-40,46-53,57-58,89-90,105-106H,14-15,20-21,26-32,34-37,71H2,1-7H3,(H,74,78)(H,76,100)(H,77,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,72,73,75)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 AJONUWHGRIXLLX-SCOIVGQKSA-N 50270987 CHEMBL443697::SYN-1327 IgG receptor FcRn large subunit p51 Homo sapiens 31 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270987&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 25090771 104116030 CHEMBL443697 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415790 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H100N18O15S2/c1-39(2)29-54(65(99)83-51(32-44-23-25-46(89)26-24-44)66(100)88-28-16-22-53(88)64(98)84-52(37-104)68(102)103)87(8)56(91)36-77-58(92)40(3)79-61(95)48(30-42-17-11-9-12-18-42)82-62(96)50(33-45-34-74-38-78-45)80-55(90)35-76-59(93)41(4)86(7)67(101)57(70(5,6)105)85-63(97)49(31-43-19-13-10-14-20-43)81-60(94)47(71)21-15-27-75-69(72)73/h9-14,17-20,23-26,34,38-41,47-54,57,89,104-105H,15-16,21-22,27-33,35-37,71H2,1-8H3,(H,74,78)(H,76,93)(H,77,92)(H,79,95)(H,80,90)(H,81,94)(H,82,96)(H,83,99)(H,84,98)(H,85,97)(H,102,103)(H4,72,73,75)/t40-,41-,47+,48+,49+,50+,51+,52+,53+,54+,57-/m1/s1 CXQJLYCTZFIOIF-IVGQHFSYSA-N 50270988 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N,3-dimethyl-3-sulfanylbutanamido]propanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]propanamido]-N-methylacetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL506261 IgG receptor FcRn large subunit p51 Homo sapiens 8000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270988&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585867 104116031 CHEMBL506261 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415791 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H100N18O16S2/c1-39(2)28-53(64(99)82-50(31-43-22-24-45(90)25-23-43)67(102)88-27-15-21-52(88)63(98)83-51(37-105)68(103)104)87(7)56(93)36-86(6)55(92)35-77-60(95)47(29-41-16-10-8-11-17-41)81-61(96)49(32-44-33-74-38-78-44)79-54(91)34-76-65(100)57(40(3)89)84-66(101)58(70(4,5)106)85-62(97)48(30-42-18-12-9-13-19-42)80-59(94)46(71)20-14-26-75-69(72)73/h8-13,16-19,22-25,33,38-40,46-53,57-58,89-90,105-106H,14-15,20-21,26-32,34-37,71H2,1-7H3,(H,74,78)(H,76,100)(H,77,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,72,73,75)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 AJONUWHGRIXLLX-SCOIVGQKSA-N 50270987 CHEMBL443697::SYN-1327 IgG receptor FcRn large subunit p51 Homo sapiens 170 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270987&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 25090771 104116030 CHEMBL443697 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415792 CC(C)C[C@H](N1CC[C@H](C1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O21S2/c1-46(2)33-64(80(126)104-60(36-50-22-24-53(112)25-23-50)83(129)110-31-13-20-62(110)79(125)105-61(44-132)78(124)103-59(38-66(89)114)74(120)96-42-69(117)109-30-14-21-63(109)84(130)131)108-32-28-51(43-108)98-67(115)40-94-73(119)56(34-48-15-8-6-9-16-48)101-76(122)58(37-52-39-92-45-97-52)99-68(116)41-95-81(127)70(47(3)111)106-82(128)71(86(4,5)133)107-77(123)57(35-49-17-10-7-11-18-49)102-75(121)55(19-12-29-93-85(90)91)100-72(118)54(87)26-27-65(88)113/h6-11,15-18,22-25,39,45-47,51,54-64,70-71,111-112,132-133H,12-14,19-21,26-38,40-44,87H2,1-5H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,119)(H,95,127)(H,96,120)(H,98,115)(H,99,116)(H,100,118)(H,101,122)(H,102,121)(H,103,124)(H,104,126)(H,105,125)(H,106,128)(H,107,123)(H,130,131)(H4,90,91,93)/t47-,51-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,70+,71-/m1/s1 TXPBKTGAPCSSJN-ZTRGSPMTSA-N 50270990 CHEMBL525263 IgG receptor FcRn large subunit p51 Homo sapiens 4900 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270990&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935302 104116033 CHEMBL525263 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415793 CC(C)C[C@H](N1CC[C@H](NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H98N18O16S2/c1-38(2)28-53(63(98)83-50(31-42-20-22-44(90)23-21-42)67(102)87-26-13-19-52(87)62(97)84-51(36-105)68(103)104)88-27-24-46(66(88)101)79-54(91)34-76-59(94)47(29-40-14-8-6-9-15-40)82-60(95)49(32-43-33-74-37-78-43)80-55(92)35-77-64(99)56(39(3)89)85-65(100)57(70(4,5)106)86-61(96)48(30-41-16-10-7-11-17-41)81-58(93)45(71)18-12-25-75-69(72)73/h6-11,14-17,20-23,33,37-39,45-53,56-57,89-90,105-106H,12-13,18-19,24-32,34-36,71H2,1-5H3,(H,74,78)(H,76,94)(H,77,99)(H,79,91)(H,80,92)(H,81,93)(H,82,95)(H,83,98)(H,84,97)(H,85,100)(H,86,96)(H,103,104)(H4,72,73,75)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,56+,57-/m1/s1 BZLGZSVSBLSGHW-WTHXZABOSA-N 50270989 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(3S)-3-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}-2-oxopyrrolidin-1-yl]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL500258 IgG receptor FcRn large subunit p51 Homo sapiens 19000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270989&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585868 104116032 CHEMBL500258 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415427 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-45(2)33-63(80(127)104-59(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-61(110)79(126)105-60(43-133)78(125)103-58(38-65(89)114)73(120)96-42-68(117)109-31-16-23-62(109)84(131)132)108(7)67(116)41-95-71(118)46(3)98-75(122)55(34-48-17-10-8-11-18-48)102-76(123)57(37-51-39-92-44-97-51)99-66(115)40-94-81(128)69(47(4)111)106-82(129)70(86(5,6)134)107-77(124)56(35-49-19-12-9-13-20-49)101-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,128)(H,95,118)(H,96,120)(H,98,122)(H,99,115)(H,100,119)(H,101,121)(H,102,123)(H,103,125)(H,104,127)(H,105,126)(H,106,129)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1 LNXBOPHNGVFQHY-UODRXTJASA-N 50270892 CHEMBL503489 IgG receptor FcRn large subunit p51 Homo sapiens 230 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270892&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935242 104115935 CHEMBL503489 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415428 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C92H128N24O22S2/c1-50(2)37-69(86(133)110-65(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-67(116)85(132)111-66(48-139)84(131)109-64(43-71(95)120)79(126)102-47-74(123)115-35-18-27-68(115)90(137)138)114(6)73(122)46-101-78(125)60(38-52-19-10-7-11-20-52)106-81(128)61(39-53-21-12-8-13-22-53)108-82(129)63(42-56-44-98-49-103-56)104-72(121)45-100-87(134)75(51(3)117)112-88(135)76(92(4,5)140)113-83(130)62(40-54-23-14-9-15-24-54)107-80(127)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,49-51,58-69,75-76,117-118,139-140H,16-18,25-27,32-43,45-48,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,103)(H,100,134)(H,101,125)(H,102,126)(H,104,121)(H,105,124)(H,106,128)(H,107,127)(H,108,129)(H,109,131)(H,110,133)(H,111,132)(H,112,135)(H,113,130)(H,137,138)(H4,96,97,99)/t51-,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,69+,75+,76-/m1/s1 MVFXXJMBTVTRQG-CQVWQLNPSA-N 50270891 CHEMBL506623 IgG receptor FcRn large subunit p51 Homo sapiens 240 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270891&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935241 104115934 CHEMBL506623 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415429 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65-,66-,67+,72+,73-/m1/s1 UTPJTGHEPBWTPW-QQIZBGRFSA-N 50270890 CHEMBL524691 IgG receptor FcRn large subunit p51 Homo sapiens 3300 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270890&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935240 104115933 CHEMBL524691 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415430 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C92H128N24O22S2/c1-49(2)37-60(81(128)111-66(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-68(116)86(133)112-67(47-139)85(132)110-65(43-71(95)120)78(125)101-46-73(122)115-35-18-27-69(115)90(137)138)106-76(123)50(3)103-80(127)61(38-52-19-10-7-11-20-52)108-82(129)62(39-53-21-12-8-13-22-53)109-83(130)64(42-56-44-98-48-102-56)104-72(121)45-100-87(134)74(51(4)117)113-88(135)75(92(5,6)140)114-84(131)63(40-54-23-14-9-15-24-54)107-79(126)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,48-51,58-69,74-75,117-118,139-140H,16-18,25-27,32-43,45-47,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,102)(H,100,134)(H,101,125)(H,103,127)(H,104,121)(H,105,124)(H,106,123)(H,107,126)(H,108,129)(H,109,130)(H,110,132)(H,111,128)(H,112,133)(H,113,135)(H,114,131)(H,137,138)(H4,96,97,99)/t50-,51-,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,69+,74+,75-/m1/s1 QQLDJXYHCLHAJS-KNFMPVJXSA-N 50270889 CHEMBL525635 IgG receptor FcRn large subunit p51 Homo sapiens 410 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270889&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935239 104115932 CHEMBL525635 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415431 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69-,70+,71+,76+,77-/m1/s1 WGJHMCNUSNAKEE-AGTNEKHFSA-N 50270888 CHEMBL525201 IgG receptor FcRn large subunit p51 Homo sapiens 720 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270888&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935238 104115931 CHEMBL525201 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415432 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C88H126N24O22S2/c1-46(2)35-56(76(123)106-61(38-51-25-27-53(114)28-26-51)85(132)112-34-15-23-64(112)81(128)107-62(44-135)79(126)104-60(40-67(91)116)73(120)97-43-69(118)110-32-16-24-65(110)86(133)134)105-80(127)63-22-14-33-111(63)84(131)47(3)99-75(122)57(36-49-17-9-7-10-18-49)103-77(124)59(39-52-41-94-45-98-52)100-68(117)42-96-82(129)70(48(4)113)108-83(130)71(88(5,6)136)109-78(125)58(37-50-19-11-8-12-20-50)102-74(121)55(21-13-31-95-87(92)93)101-72(119)54(89)29-30-66(90)115/h7-12,17-20,25-28,41,45-48,54-65,70-71,113-114,135-136H,13-16,21-24,29-40,42-44,89H2,1-6H3,(H2,90,115)(H2,91,116)(H,94,98)(H,96,129)(H,97,120)(H,99,122)(H,100,117)(H,101,119)(H,102,121)(H,103,124)(H,104,126)(H,105,127)(H,106,123)(H,107,128)(H,108,130)(H,109,125)(H,133,134)(H4,92,93,95)/t47-,48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,70+,71-/m1/s1 XKKMTYJKVIWWPI-KKCYLYMESA-N 50270887 CHEMBL505622 IgG receptor FcRn large subunit p51 Homo sapiens 430 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270887&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935237 104115930 CHEMBL505622 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415433 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-44(2)33-55(76(123)105-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)80(127)106-61(42-133)79(126)104-59(38-65(89)114)73(120)95-41-67(116)109-31-16-23-63(109)84(131)132)101-71(118)46(4)97-70(117)45(3)98-75(122)56(34-48-17-10-8-11-18-48)103-77(124)58(37-51-39-92-43-96-51)99-66(115)40-94-81(128)68(47(5)111)107-82(129)69(86(6,7)134)108-78(125)57(35-49-19-12-9-13-20-49)102-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,43-47,53-63,68-69,111-112,133-134H,14-16,21-23,28-38,40-42,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,128)(H,95,120)(H,97,117)(H,98,122)(H,99,115)(H,100,119)(H,101,118)(H,102,121)(H,103,124)(H,104,126)(H,105,123)(H,106,127)(H,107,129)(H,108,125)(H,131,132)(H4,90,91,93)/t45-,46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,68+,69-/m1/s1 DXFHHMMOGGSCIW-RSVHAWIGSA-N 50270886 CHEMBL525018 IgG receptor FcRn large subunit p51 Homo sapiens 450 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270886&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935236 104115929 CHEMBL525018 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415434 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H122N24O22S2/c1-44(2)32-54(75(122)104-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)105-60(42-132)78(125)103-58(37-64(88)113)72(119)95-41-67(116)108-30-15-22-62(108)83(130)131)98-65(114)39-93-70(117)45(3)97-74(121)55(33-47-16-9-7-10-17-47)102-76(123)57(36-50-38-91-43-96-50)99-66(115)40-94-80(127)68(46(4)110)106-81(128)69(85(5,6)133)107-77(124)56(34-48-18-11-8-12-19-48)101-73(120)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,43-46,52-62,68-69,110-111,132-133H,13-15,20-22,27-37,39-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,117)(H,94,127)(H,95,119)(H,97,121)(H,98,114)(H,99,115)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1 AURKCJKHUJBTOW-LVOPMODUSA-N 50270885 CHEMBL508377 IgG receptor FcRn large subunit p51 Homo sapiens 490 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270885&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935235 104115928 CHEMBL508377 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415435 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C68H101N17O16S2/c1-38(2)30-51(62(96)79-48(33-42-22-24-43(87)25-23-42)65(99)85-29-15-21-50(85)61(95)80-49(37-102)66(100)101)84(7)54(90)36-83(6)53(89)35-75-58(92)46(31-40-16-10-8-11-17-40)78-59(93)45(26-27-69)76-52(88)34-74-63(97)55(39(3)86)81-64(98)56(68(4,5)103)82-60(94)47(32-41-18-12-9-13-19-41)77-57(91)44(70)20-14-28-73-67(71)72/h8-13,16-19,22-25,38-39,44-51,55-56,86-87,102-103H,14-15,20-21,26-37,69-70H2,1-7H3,(H,74,97)(H,75,92)(H,76,88)(H,77,91)(H,78,93)(H,79,96)(H,80,95)(H,81,98)(H,82,94)(H,100,101)(H4,71,72,73)/t39-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1 VDVYPUQKQQZAQP-VDKARCBXSA-N 50270916 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-4-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}butanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526300 IgG receptor FcRn large subunit p51 Homo sapiens 1200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270916&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585796 104115959 CHEMBL526300 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415436 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccsc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N16O16S3/c1-40(2)30-54(65(98)81-51(33-44-22-24-46(89)25-23-44)68(101)87-28-15-21-53(87)64(97)82-52(38-104)69(102)103)86(7)57(92)37-85(6)56(91)36-77-61(94)48(31-42-16-10-8-11-17-42)80-62(95)49(34-45-26-29-106-39-45)78-55(90)35-76-66(99)58(41(3)88)83-67(100)59(71(4,5)105)84-63(96)50(32-43-18-12-9-13-19-43)79-60(93)47(72)20-14-27-75-70(73)74/h8-13,16-19,22-26,29,39-41,47-54,58-59,88-89,104-105H,14-15,20-21,27-28,30-38,72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 BFALDNZBLNDWMU-PMHNZZKJSA-N 50270943 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(thiophen-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501094 IgG receptor FcRn large subunit p51 Homo sapiens 2000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270943&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585823 104115986 CHEMBL501094 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415437 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccncc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-27,29-30,41-42,48-55,59-60,90-91,106-107H,14-15,20-21,28,31-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 RBGABFZURPEVTF-OFRDJWLHSA-N 50270942 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL503673 IgG receptor FcRn large subunit p51 Homo sapiens 67 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270942&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585822 104115985 CHEMBL503673 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415438 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccnc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-14,17-21,24-28,36,41-42,48-55,59-60,90-91,106-107H,15-16,22-23,29-35,37-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 HXAVKIDMUJTIEM-OFRDJWLHSA-N 50270941 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501395 IgG receptor FcRn large subunit p51 Homo sapiens 640 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270941&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585821 104115984 CHEMBL501395 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415439 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(35-45-25-27-47(91)28-26-45)69(103)89-31-17-24-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-18-10-8-11-19-43)82-63(97)51(36-46-22-14-15-29-76-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)50(34-44-20-12-9-13-21-44)81-61(95)48(73)23-16-30-77-71(74)75/h8-15,18-22,25-29,41-42,48-55,59-60,90-91,106-107H,16-17,23-24,30-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 VXNSUGHXYUJKAG-OFRDJWLHSA-N 50270940 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-2-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL507807 IgG receptor FcRn large subunit p51 Homo sapiens 330 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270940&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585820 104115983 CHEMBL507807 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415440 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnn[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H99N19O16S2/c1-38(2)28-52(63(99)80-49(31-42-22-24-44(90)25-23-42)66(102)88-27-15-21-51(88)62(98)81-50(37-105)67(103)104)87(7)55(93)36-86(6)54(92)35-75-59(95)46(29-40-16-10-8-11-17-40)79-60(96)48(32-43-33-76-85-84-43)77-53(91)34-74-64(100)56(39(3)89)82-65(101)57(69(4,5)106)83-61(97)47(30-41-18-12-9-13-19-41)78-58(94)45(70)20-14-26-73-68(71)72/h8-13,16-19,22-25,33,38-39,45-52,56-57,89-90,105-106H,14-15,20-21,26-32,34-37,70H2,1-7H3,(H,74,100)(H,75,95)(H,77,91)(H,78,94)(H,79,96)(H,80,99)(H,81,98)(H,82,101)(H,83,97)(H,103,104)(H4,71,72,73)(H,76,84,85)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 SIPWBDDMNAUTNG-SJGHIIINSA-N 50270939 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-1,2,3-triazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL505609 IgG receptor FcRn large subunit p51 Homo sapiens 320 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270939&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585819 104115982 CHEMBL505609 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415441 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1csc[n+]1C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(N)=O InChI=1S/C71H102N18O15S3/c1-40(2)29-54(66(101)82-51(32-44-23-25-46(91)26-24-44)69(104)89-28-16-22-53(89)65(100)83-52(37-105)60(73)95)88(8)57(94)36-86(6)56(93)35-78-62(97)48(30-42-17-11-9-12-18-42)81-63(98)50(33-45-38-107-39-87(45)7)79-55(92)34-77-67(102)58(41(3)90)84-68(103)59(71(4,5)106)85-64(99)49(31-43-19-13-10-14-20-43)80-61(96)47(72)21-15-27-76-70(74)75/h9-14,17-20,23-26,38-41,47-54,58-59,90H,15-16,21-22,27-37,72H2,1-8H3,(H17-,73,74,75,76,77,78,79,80,81,82,83,84,85,91,92,95,96,97,98,99,100,101,102,103,105,106)/p+1/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 UUUMCMHCHPLAPZ-PMHNZZKJSA-O 50270938 4-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-2-{[(1S)-1-({[({[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}pyrrolidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl}-3-methylbutyl](methyl)carbamoyl}methyl)(methyl)carbamoyl]methyl}carbamoyl)-2-phenylethyl]carbamoyl}ethyl]-3-methyl-1,3-thiazol-3-ium::CHEMBL506195 IgG receptor FcRn large subunit p51 Homo sapiens 110 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270938&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585818 104115981 CHEMBL506195 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415442 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cscn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H99N17O16S3/c1-39(2)28-53(64(98)81-50(31-43-22-24-45(89)25-23-43)67(101)87-27-15-21-52(87)63(97)82-51(36-104)68(102)103)86(7)56(92)35-85(6)55(91)34-76-60(94)47(29-41-16-10-8-11-17-41)80-61(95)49(32-44-37-106-38-77-44)78-54(90)33-75-65(99)57(40(3)88)83-66(100)58(70(4,5)105)84-62(96)48(30-42-18-12-9-13-19-42)79-59(93)46(71)20-14-26-74-69(72)73/h8-13,16-19,22-25,37-40,46-53,57-58,88-89,104-105H,14-15,20-21,26-36,71H2,1-7H3,(H,75,99)(H,76,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,72,73,74)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 GYWQUYXIOMIUSN-SCOIVGQKSA-N 50270937 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1,3-thiazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526373 IgG receptor FcRn large subunit p51 Homo sapiens 840 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270937&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585817 104115980 CHEMBL526373 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415443 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C67H98N16O16S2/c1-37(2)29-50(61(94)77-47(32-42-23-25-43(85)26-24-42)64(97)83-28-16-22-49(83)60(93)78-48(36-100)65(98)99)82(8)53(88)35-81(7)52(87)34-73-58(91)45(30-40-17-11-9-12-18-40)75-56(89)38(3)74-51(86)33-72-62(95)54(39(4)84)79-63(96)55(67(5,6)101)80-59(92)46(31-41-19-13-10-14-20-41)76-57(90)44(68)21-15-27-71-66(69)70/h9-14,17-20,23-26,37-39,44-50,54-55,84-85,100-101H,15-16,21-22,27-36,68H2,1-8H3,(H,72,95)(H,73,91)(H,74,86)(H,75,89)(H,76,90)(H,77,94)(H,78,93)(H,79,96)(H,80,92)(H,98,99)(H4,69,70,71)/t38-,39+,44-,45-,46-,47-,48-,49-,50-,54-,55+/m0/s1 PLTHUPZHFFCLIW-SFICEKSFSA-N 50270953 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525232 IgG receptor FcRn large subunit p51 Homo sapiens 13000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270953&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585833 104115996 CHEMBL525232 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415444 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H102N16O16S2/c1-42(2)33-56(67(100)83-53(37-47-27-29-48(91)30-28-47)70(103)89-32-18-26-55(89)66(99)84-54(41-106)71(104)105)88(7)59(94)40-87(6)58(93)39-79-63(96)50(34-44-19-11-8-12-20-44)82-64(97)51(35-45-21-13-9-14-22-45)80-57(92)38-78-68(101)60(43(3)90)85-69(102)61(73(4,5)107)86-65(98)52(36-46-23-15-10-16-24-46)81-62(95)49(74)25-17-31-77-72(75)76/h8-16,19-24,27-30,42-43,49-56,60-61,90-91,106-107H,17-18,25-26,31-41,74H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,75,76,77)/t43-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 XPNACTKSNQJUKY-IQKMKRTQSA-N 50270952 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-phenylpropanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524718 IgG receptor FcRn large subunit p51 Homo sapiens 4200 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270952&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585832 104115995 CHEMBL524718 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415445 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCNCC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-25,41-42,46,48-55,59-60,76,90-91,106-107H,14-15,20-21,26-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 BMLIWXUJOHYWPK-OFRDJWLHSA-N 50270951 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525431 IgG receptor FcRn large subunit p51 Homo sapiens 6400 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270951&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585831 104115994 CHEMBL525431 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415446 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCNC1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H107N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-13,17-20,24-27,41-42,46,48-55,59-60,76,90-91,106-107H,14-16,21-23,28-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,46?,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 SDEOUMVKASFBFG-SQUBLMHESA-N 50270950 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(piperidin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526499 IgG receptor FcRn large subunit p51 Homo sapiens 860 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270950&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585830 104115993 CHEMBL526499 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415447 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cc[nH]c1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H101N17O16S2/c1-40(2)30-54(65(99)82-51(33-44-22-24-46(90)25-23-44)68(102)88-29-15-21-53(88)64(98)83-52(39-105)69(103)104)87(7)57(93)38-86(6)56(92)37-78-61(95)48(31-42-16-10-8-11-17-42)81-62(96)49(34-45-26-28-75-35-45)79-55(91)36-77-66(100)58(41(3)89)84-67(101)59(71(4,5)106)85-63(97)50(32-43-18-12-9-13-19-43)80-60(94)47(72)20-14-27-76-70(73)74/h8-13,16-19,22-26,28,35,40-41,47-54,58-59,75,89-90,105-106H,14-15,20-21,27,29-34,36-39,72H2,1-7H3,(H,77,100)(H,78,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,73,74,76)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 NGAVDNSZVZELRG-PMHNZZKJSA-N 50270949 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-pyrrol-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL510720 IgG receptor FcRn large subunit p51 Homo sapiens 13000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270949&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585829 104115992 CHEMBL510720 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415448 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H103N17O16S2/c1-41(2)32-56(67(101)84-53(36-46-24-28-48(92)29-25-46)70(104)90-31-15-21-55(90)66(100)85-54(40-107)71(105)106)89(7)59(95)39-88(6)58(94)38-80-63(97)50(33-43-16-10-8-11-17-43)83-64(98)51(35-45-22-26-47(74)27-23-45)81-57(93)37-79-68(102)60(42(3)91)86-69(103)61(73(4,5)108)87-65(99)52(34-44-18-12-9-13-19-44)82-62(96)49(75)20-14-30-78-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,91-92,107-108H,14-15,20-21,30-40,74-75H2,1-7H3,(H,79,102)(H,80,97)(H,81,93)(H,82,96)(H,83,98)(H,84,101)(H,85,100)(H,86,103)(H,87,99)(H,105,106)(H4,76,77,78)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 VDTFZUDODVYEAQ-GAIGFMGPSA-N 50270948 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-aminophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504837 IgG receptor FcRn large subunit p51 Homo sapiens 1100 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270948&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585828 104115991 CHEMBL504837 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415449 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C74H105N19O16S2/c1-41(2)32-56(67(104)87-53(36-46-24-28-48(95)29-25-46)70(107)93-31-15-21-55(93)66(103)88-54(40-110)71(108)109)92(7)59(98)39-91(6)58(97)38-82-63(100)50(33-43-16-10-8-11-17-43)86-64(101)51(35-45-22-26-47(27-23-45)83-73(78)79)84-57(96)37-81-68(105)60(42(3)94)89-69(106)61(74(4,5)111)90-65(102)52(34-44-18-12-9-13-19-44)85-62(99)49(75)20-14-30-80-72(76)77/h8-13,16-19,22-29,41-42,49-56,60-61,94-95,110-111H,14-15,20-21,30-40,75H2,1-7H3,(H,81,105)(H,82,100)(H,84,96)(H,85,99)(H,86,101)(H,87,104)(H,88,103)(H,89,106)(H,90,102)(H,108,109)(H4,76,77,80)(H4,78,79,83)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,60+,61-/m1/s1 LTJSIONUIYPBNM-GAIGFMGPSA-N 50270947 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-carbamimidamidophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504003 IgG receptor FcRn large subunit p51 Homo sapiens 73 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270947&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935284 104115990 CHEMBL504003 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415450 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N19O16S2/c1-39(2)31-52(63(100)83-49(34-43-24-26-44(91)27-25-43)66(103)89-30-16-23-51(89)62(99)84-50(38-106)67(104)105)88(7)55(94)37-87(6)54(93)36-79-59(96)47(32-41-17-10-8-11-18-41)82-60(97)46(22-15-29-77-69(74)75)80-53(92)35-78-64(101)56(40(3)90)85-65(102)57(70(4,5)107)86-61(98)48(33-42-19-12-9-13-20-42)81-58(95)45(71)21-14-28-76-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,90-91,106-107H,14-16,21-23,28-38,71H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,72,73,76)(H4,74,75,77)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 UYTJXNOKSSRZIA-ZTUWISBESA-N 50270946 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-5-carbamimidamidopentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL509335 IgG receptor FcRn large subunit p51 Homo sapiens 500 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270946&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585826 104115989 CHEMBL509335 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415451 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H105N17O16S2/c1-40(2)32-53(64(98)81-50(35-44-25-27-45(89)28-26-44)67(101)87-31-17-24-52(87)63(97)82-51(39-104)68(102)103)86(7)56(92)38-85(6)55(91)37-77-60(94)48(33-42-18-10-8-11-19-42)80-61(95)47(23-14-15-29-71)78-54(90)36-76-65(99)57(41(3)88)83-66(100)58(70(4,5)105)84-62(96)49(34-43-20-12-9-13-21-43)79-59(93)46(72)22-16-30-75-69(73)74/h8-13,18-21,25-28,40-41,46-53,57-58,88-89,104-105H,14-17,22-24,29-39,71-72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 ZWGRTIDGLKIEMS-XMFJQSQOSA-N 50270945 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-6-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}hexanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL524297 IgG receptor FcRn large subunit p51 Homo sapiens 1100 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270945&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585825 104115988 CHEMBL524297 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415452 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H103N17O16S2/c1-39(2)31-52(63(97)80-49(34-43-24-26-44(88)27-25-43)66(100)86-30-16-23-51(86)62(96)81-50(38-103)67(101)102)85(7)55(91)37-84(6)54(90)36-76-59(93)47(32-41-17-10-8-11-18-41)79-60(94)46(22-14-28-70)77-53(89)35-75-64(98)56(40(3)87)82-65(99)57(69(4,5)104)83-61(95)48(33-42-19-12-9-13-20-42)78-58(92)45(71)21-15-29-74-68(72)73/h8-13,17-20,24-27,39-40,45-52,56-57,87-88,103-104H,14-16,21-23,28-38,70-71H2,1-7H3,(H,75,98)(H,76,93)(H,77,89)(H,78,92)(H,79,94)(H,80,97)(H,81,96)(H,82,99)(H,83,95)(H,101,102)(H4,72,73,74)/t40-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 BSBUVESIVQAPEC-ZTUWISBESA-N 50270944 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-5-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}pentanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504336 IgG receptor FcRn large subunit p51 Homo sapiens 1200 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270944&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585824 104115987 CHEMBL504336 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415453 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C68H101N17O16S2/c1-38(2)30-51(62(96)79-48(33-42-22-24-43(87)25-23-42)65(99)85-29-15-21-50(85)61(95)80-49(37-102)66(100)101)84(7)54(90)36-83(6)53(89)35-75-58(92)46(31-40-16-10-8-11-17-40)78-59(93)45(26-27-69)76-52(88)34-74-63(97)55(39(3)86)81-64(98)56(68(4,5)103)82-60(94)47(32-41-18-12-9-13-19-41)77-57(91)44(70)20-14-28-73-67(71)72/h8-13,16-19,22-25,38-39,44-51,55-56,86-87,102-103H,14-15,20-21,26-37,69-70H2,1-7H3,(H,74,97)(H,75,92)(H,76,88)(H,77,91)(H,78,93)(H,79,96)(H,80,95)(H,81,98)(H,82,94)(H,100,101)(H4,71,72,73)/t39-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1 VDVYPUQKQQZAQP-VDKARCBXSA-N 50270916 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-4-amino-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}butanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526300 IgG receptor FcRn large subunit p51 Homo sapiens 1200 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270916&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585796 104115959 CHEMBL526300 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415454 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccsc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N16O16S3/c1-40(2)30-54(65(98)81-51(33-44-22-24-46(89)25-23-44)68(101)87-28-15-21-53(87)64(97)82-52(38-104)69(102)103)86(7)57(92)37-85(6)56(91)36-77-61(94)48(31-42-16-10-8-11-17-42)80-62(95)49(34-45-26-29-106-39-45)78-55(90)35-76-66(99)58(41(3)88)83-67(100)59(71(4,5)105)84-63(96)50(32-43-18-12-9-13-19-43)79-60(93)47(72)20-14-27-75-70(73)74/h8-13,16-19,22-26,29,39-41,47-54,58-59,88-89,104-105H,14-15,20-21,27-28,30-38,72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 BFALDNZBLNDWMU-PMHNZZKJSA-N 50270943 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(thiophen-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501094 IgG receptor FcRn large subunit p51 Homo sapiens 3000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270943&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585823 104115986 CHEMBL501094 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415455 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccncc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-27,29-30,41-42,48-55,59-60,90-91,106-107H,14-15,20-21,28,31-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 RBGABFZURPEVTF-OFRDJWLHSA-N 50270942 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL503673 IgG receptor FcRn large subunit p51 Homo sapiens 280 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270942&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585822 104115985 CHEMBL503673 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415456 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccnc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-14,17-21,24-28,36,41-42,48-55,59-60,90-91,106-107H,15-16,22-23,29-35,37-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 HXAVKIDMUJTIEM-OFRDJWLHSA-N 50270941 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-3-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL501395 IgG receptor FcRn large subunit p51 Homo sapiens 260 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270941&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585821 104115984 CHEMBL501395 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415457 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(35-45-25-27-47(91)28-26-45)69(103)89-31-17-24-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-18-10-8-11-19-43)82-63(97)51(36-46-22-14-15-29-76-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)50(34-44-20-12-9-13-21-44)81-61(95)48(73)23-16-30-77-71(74)75/h8-15,18-22,25-29,41-42,48-55,59-60,90-91,106-107H,16-17,23-24,30-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1 VXNSUGHXYUJKAG-OFRDJWLHSA-N 50270940 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(pyridin-2-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL507807 IgG receptor FcRn large subunit p51 Homo sapiens 410 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270940&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585820 104115983 CHEMBL507807 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415458 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnn[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C69H99N19O16S2/c1-38(2)28-52(63(99)80-49(31-42-22-24-44(90)25-23-42)66(102)88-27-15-21-51(88)62(98)81-50(37-105)67(103)104)87(7)55(93)36-86(6)54(92)35-75-59(95)46(29-40-16-10-8-11-17-40)79-60(96)48(32-43-33-76-85-84-43)77-53(91)34-74-64(100)56(39(3)89)82-65(101)57(69(4,5)106)83-61(97)47(30-41-18-12-9-13-19-41)78-58(94)45(70)20-14-26-73-68(71)72/h8-13,16-19,22-25,33,38-39,45-52,56-57,89-90,105-106H,14-15,20-21,26-32,34-37,70H2,1-7H3,(H,74,100)(H,75,95)(H,77,91)(H,78,94)(H,79,96)(H,80,99)(H,81,98)(H,82,101)(H,83,97)(H,103,104)(H4,71,72,73)(H,76,84,85)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1 SIPWBDDMNAUTNG-SJGHIIINSA-N 50270939 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-1,2,3-triazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL505609 IgG receptor FcRn large subunit p51 Homo sapiens 360 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270939&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585819 104115982 CHEMBL505609 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415459 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1csc[n+]1C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(N)=O InChI=1S/C71H102N18O15S3/c1-40(2)29-54(66(101)82-51(32-44-23-25-46(91)26-24-44)69(104)89-28-16-22-53(89)65(100)83-52(37-105)60(73)95)88(8)57(94)36-86(6)56(93)35-78-62(97)48(30-42-17-11-9-12-18-42)81-63(98)50(33-45-38-107-39-87(45)7)79-55(92)34-77-67(102)58(41(3)90)84-68(103)59(71(4,5)106)85-64(99)49(31-43-19-13-10-14-20-43)80-61(96)47(72)21-15-27-76-70(74)75/h9-14,17-20,23-26,38-41,47-54,58-59,90H,15-16,21-22,27-37,72H2,1-8H3,(H17-,73,74,75,76,77,78,79,80,81,82,83,84,85,91,92,95,96,97,98,99,100,101,102,103,105,106)/p+1/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1 UUUMCMHCHPLAPZ-PMHNZZKJSA-O 50270938 4-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-2-{[(1S)-1-({[({[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}pyrrolidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl}-3-methylbutyl](methyl)carbamoyl}methyl)(methyl)carbamoyl]methyl}carbamoyl)-2-phenylethyl]carbamoyl}ethyl]-3-methyl-1,3-thiazol-3-ium::CHEMBL506195 IgG receptor FcRn large subunit p51 Homo sapiens 110 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270938&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585818 104115981 CHEMBL506195 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415460 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cscn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C70H99N17O16S3/c1-39(2)28-53(64(98)81-50(31-43-22-24-45(89)25-23-43)67(101)87-27-15-21-52(87)63(97)82-51(36-104)68(102)103)86(7)56(92)35-85(6)55(91)34-76-60(94)47(29-41-16-10-8-11-17-41)80-61(95)49(32-44-37-106-38-77-44)78-54(90)33-75-65(99)57(40(3)88)83-66(100)58(70(4,5)105)84-62(96)48(30-42-18-12-9-13-19-42)79-59(93)46(71)20-14-26-74-69(72)73/h8-13,16-19,22-25,37-40,46-53,57-58,88-89,104-105H,14-15,20-21,26-36,71H2,1-7H3,(H,75,99)(H,76,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,72,73,74)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1 GYWQUYXIOMIUSN-SCOIVGQKSA-N 50270937 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1,3-thiazol-4-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526373 IgG receptor FcRn large subunit p51 Homo sapiens 1100 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270937&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585817 104115980 CHEMBL526373 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415461 CC(C)C[C@H](NC(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C72H102N18O16/c1-40(2)31-51(62(96)86-55(34-46-24-26-48(92)27-25-46)70(104)90-30-16-23-56(90)66(100)80-42(5)71(105)106)82-58(94)38-89-29-14-13-22-50(69(89)103)83-63(97)52(32-44-17-9-7-10-18-44)85-64(98)54(35-47-36-76-39-79-47)81-57(93)37-78-67(101)60(43(6)91)88-68(102)59(41(3)4)87-65(99)53(33-45-19-11-8-12-20-45)84-61(95)49(73)21-15-28-77-72(74)75/h7-12,17-20,24-27,36,39-43,49-56,59-60,91-92H,13-16,21-23,28-35,37-38,73H2,1-6H3,(H,76,79)(H,78,101)(H,80,100)(H,81,93)(H,82,94)(H,83,97)(H,84,95)(H,85,98)(H,86,96)(H,87,99)(H,88,102)(H,105,106)(H4,74,75,77)/t42-,43+,49-,50+,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 BYQYPTXOMZUXOR-OYXZUBOTSA-N 50270986 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL500441 IgG receptor FcRn large subunit p51 Homo sapiens 23000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270986&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585866 104116029 CHEMBL500441 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415462 CC(C)C[C@H](NC(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C71H100N18O16/c1-39(2)30-50(61(95)85-54(33-45-23-25-47(91)26-24-45)69(103)89-29-15-22-55(89)65(99)79-41(5)70(104)105)81-57(93)37-88-28-14-21-49(68(88)102)82-62(96)51(31-43-16-9-7-10-17-43)84-63(97)53(34-46-35-75-38-78-46)80-56(92)36-77-66(100)59(42(6)90)87-67(101)58(40(3)4)86-64(98)52(32-44-18-11-8-12-19-44)83-60(94)48(72)20-13-27-76-71(73)74/h7-12,16-19,23-26,35,38-42,48-55,58-59,90-91H,13-15,20-22,27-34,36-37,72H2,1-6H3,(H,75,78)(H,77,100)(H,79,99)(H,80,92)(H,81,93)(H,82,96)(H,83,94)(H,84,97)(H,85,95)(H,86,98)(H,87,101)(H,104,105)(H4,73,74,76)/t41-,42+,48-,49+,50-,51-,52-,53-,54-,55-,58-,59-/m0/s1 CHCLMWAHFABHFZ-KEACGAIKSA-N 50270985 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL508902 IgG receptor FcRn large subunit p51 Homo sapiens 38000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270985&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585865 104116028 CHEMBL508902 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415463 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C70H100N18O16/c1-39(2)29-54(65(99)83-52(32-45-23-25-47(90)26-24-45)68(102)88-28-16-22-53(88)64(98)79-41(5)69(103)104)87(8)57(93)37-86(7)56(92)36-77-61(95)49(30-43-17-11-9-12-18-43)82-62(96)51(33-46-34-74-38-78-46)80-55(91)35-76-66(100)59(42(6)89)85-67(101)58(40(3)4)84-63(97)50(31-44-19-13-10-14-20-44)81-60(94)48(71)21-15-27-75-70(72)73/h9-14,17-20,23-26,34,38-42,48-54,58-59,89-90H,15-16,21-22,27-33,35-37,71H2,1-8H3,(H,74,78)(H,76,100)(H,77,95)(H,79,98)(H,80,91)(H,81,94)(H,82,96)(H,83,99)(H,84,97)(H,85,101)(H,103,104)(H4,72,73,75)/t41-,42+,48-,49-,50-,51-,52-,53-,54-,58-,59-/m0/s1 GBPJUAXDJHWEIX-QCRZSQONSA-N 50270984 (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid::CHEMBL499121 IgG receptor FcRn large subunit p51 Homo sapiens 37000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270984&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585864 104116027 CHEMBL499121 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415464 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O24/c1-43(2)29-52(73(121)101-57(32-47-20-22-49(110)23-21-47)80(128)106-28-11-18-60(106)78(126)103-58(40-107)76(124)100-56(34-63(85)112)71(119)93-39-67(116)105-27-12-19-61(105)81(129)130)95-65(114)37-90-64(113)36-91-70(118)53(30-45-13-6-4-7-14-45)98-75(123)55(33-48-35-88-42-94-48)96-66(115)38-92-79(127)68(44(3)109)104-77(125)59(41-108)102-74(122)54(31-46-15-8-5-9-16-46)99-72(120)51(17-10-26-89-82(86)87)97-69(117)50(83)24-25-62(84)111/h4-9,13-16,20-23,35,42-44,50-61,68,107-110H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,111)(H2,85,112)(H,88,94)(H,90,113)(H,91,118)(H,92,127)(H,93,119)(H,95,114)(H,96,115)(H,97,117)(H,98,123)(H,99,120)(H,100,124)(H,101,121)(H,102,122)(H,103,126)(H,104,125)(H,129,130)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 AUSBKGPHCIVTPH-YNALCKGOSA-N 50270983 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506645 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270983&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935301 104116026 CHEMBL506645 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415465 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H125N25O24/c1-47(2)35-58(80(129)109-63(38-51-23-25-53(114)26-24-51)85(134)112-34-13-21-64(112)83(132)105-57(28-30-72(121)122)78(127)108-62(40-67(91)116)76(125)99-45-71(120)111-33-14-22-65(111)86(135)136)101-69(118)43-96-68(117)42-97-75(124)59(36-49-15-6-4-7-16-49)106-82(131)61(39-52-41-94-46-100-52)102-70(119)44-98-84(133)73(48(3)113)110-79(128)55(19-10-11-31-88)104-81(130)60(37-50-17-8-5-9-18-50)107-77(126)56(20-12-32-95-87(92)93)103-74(123)54(89)27-29-66(90)115/h4-9,15-18,23-26,41,46-48,54-65,73,113-114H,10-14,19-22,27-40,42-45,88-89H2,1-3H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,124)(H,98,133)(H,99,125)(H,101,118)(H,102,119)(H,103,123)(H,104,130)(H,105,132)(H,106,131)(H,107,126)(H,108,127)(H,109,129)(H,110,128)(H,121,122)(H,135,136)(H4,92,93,95)/t48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,73+/m1/s1 ZLPUHJRLIMHCEO-YNSMZBETSA-N 50270982 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]hexanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL510066 IgG receptor FcRn large subunit p51 Homo sapiens 33000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270982&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935300 104116025 CHEMBL510066 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415466 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)34-57(79(128)108-62(37-50-22-24-52(113)25-23-50)84(133)111-33-12-20-63(111)82(131)104-56(27-29-71(120)121)77(126)107-61(39-66(90)115)75(124)98-44-70(119)110-32-13-21-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)58(35-48-14-6-4-7-15-48)105-81(130)60(38-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-78(127)54(18-10-30-87)103-80(129)59(36-49-16-8-5-9-17-49)106-76(125)55(19-11-31-94-86(91)92)102-73(122)53(88)26-28-65(89)114/h4-9,14-17,22-25,40,45-47,53-64,72,112-113H,10-13,18-21,26-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,129)(H,104,131)(H,105,130)(H,106,125)(H,107,126)(H,108,128)(H,109,127)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 PNSFCJCYFWJUQB-JQYWQRDCSA-N 50270981 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-5-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]pentanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508221 IgG receptor FcRn large subunit p51 Homo sapiens 30000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270981&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935299 104116024 CHEMBL508221 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415467 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)33-56(78(127)107-61(36-49-20-22-51(112)23-21-49)83(132)110-32-11-18-62(110)81(130)103-54(25-27-70(119)120)76(125)106-60(38-65(89)114)74(123)97-43-69(118)109-31-12-19-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)57(34-47-13-6-4-7-14-47)104-80(129)59(37-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-77(126)55(28-29-86)102-79(128)58(35-48-15-8-5-9-16-48)105-75(124)53(17-10-30-93-85(90)91)101-72(121)52(87)24-26-64(88)113/h4-9,13-16,20-23,39,44-46,52-63,71,111-112H,10-12,17-19,24-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,128)(H,103,130)(H,104,129)(H,105,124)(H,106,125)(H,107,127)(H,108,126)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 AWRLMOAKWKXHJL-QZSPZITESA-N 50270980 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-4-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]butanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508398 IgG receptor FcRn large subunit p51 Homo sapiens 81000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270980&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935298 104116023 CHEMBL508398 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415468 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)105-59(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)101-53(25-27-69(118)119)75(124)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-79(128)60(37-85)106-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-26-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,129)(H,102,127)(H,103,123)(H,104,124)(H,105,125)(H,106,126)(H,107,128)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 BDJLVBQVOYHCRD-AZARTFGISA-N 50270979 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-3-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]propanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-4-carboxybutanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524345 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270979&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935297 104116022 CHEMBL524345 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415469 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)33-56(78(127)108-62(36-50-23-25-52(113)26-24-50)84(133)111-32-13-21-63(111)82(131)107-61(39-71(120)121)81(130)106-60(38-66(90)115)75(124)98-44-70(119)110-31-14-22-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)57(34-48-15-6-4-7-16-48)104-80(129)59(37-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-77(126)54(19-10-11-29-87)103-79(128)58(35-49-17-8-5-9-18-49)105-76(125)55(20-12-30-94-86(91)92)102-73(122)53(88)27-28-65(89)114/h4-9,15-18,23-26,40,45-47,53-64,72,112-113H,10-14,19-22,27-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,128)(H,104,129)(H,105,125)(H,106,130)(H,107,131)(H,108,127)(H,109,126)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 BMVSGWJINAYAQP-JQYWQRDCSA-N 50270978 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]hexanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL527072 IgG receptor FcRn large subunit p51 Homo sapiens 60000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270978&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935296 104116021 CHEMBL527072 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415470 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)32-55(77(126)107-61(35-49-22-24-51(112)25-23-49)83(132)110-31-12-20-62(110)81(130)106-60(38-70(119)120)80(129)105-59(37-65(89)114)74(123)97-43-69(118)109-30-13-21-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)56(33-47-14-6-4-7-15-47)103-79(128)58(36-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-76(125)53(18-10-28-86)102-78(127)57(34-48-16-8-5-9-17-48)104-75(124)54(19-11-29-93-85(90)91)101-72(121)52(87)26-27-64(88)113/h4-9,14-17,22-25,39,44-46,52-63,71,111-112H,10-13,18-21,26-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,127)(H,103,128)(H,104,124)(H,105,129)(H,106,130)(H,107,126)(H,108,125)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 FFEZZIFVIJJQRY-QZSPZITESA-N 50270977 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-5-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]pentanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL510674 IgG receptor FcRn large subunit p51 Homo sapiens 120000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270977&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935295 104116020 CHEMBL510674 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415471 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)106-60(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)105-59(37-69(118)119)79(128)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-75(124)53(26-27-85)101-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-25-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,126)(H,102,127)(H,103,123)(H,104,128)(H,105,129)(H,106,125)(H,107,124)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 YLGGPWMPBOKPRB-AZARTFGISA-N 50270976 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-4-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]butanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503191 IgG receptor FcRn large subunit p51 Homo sapiens 31000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270976&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935294 104116019 CHEMBL503191 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415472 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H117N25O24/c1-43(2)29-52(74(123)104-58(32-47-20-22-49(110)23-21-47)81(130)108-28-11-18-60(108)79(128)103-57(35-68(117)118)77(126)102-56(34-63(87)112)72(121)95-41-67(116)107-27-12-19-61(107)82(131)132)97-65(114)39-92-64(113)38-93-71(120)53(30-45-13-6-4-7-14-45)100-76(125)55(33-48-37-90-42-96-48)98-66(115)40-94-80(129)69(44(3)109)106-78(127)59(36-84)105-75(124)54(31-46-15-8-5-9-16-46)101-73(122)51(17-10-26-91-83(88)89)99-70(119)50(85)24-25-62(86)111/h4-9,13-16,20-23,37,42-44,50-61,69,109-110H,10-12,17-19,24-36,38-41,84-85H2,1-3H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,120)(H,94,129)(H,95,121)(H,97,114)(H,98,115)(H,99,119)(H,100,125)(H,101,122)(H,102,126)(H,103,128)(H,104,123)(H,105,124)(H,106,127)(H,117,118)(H,131,132)(H4,88,89,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,69+/m1/s1 MTEDFSGETUDNLM-YHTHZICESA-N 50270975 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-3-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]propanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL507848 IgG receptor FcRn large subunit p51 Homo sapiens 120000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270975&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935293 104116018 CHEMBL507848 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415473 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H125N25O24/c1-47(2)35-58(80(129)109-63(38-51-23-25-53(114)26-24-51)85(134)112-34-13-21-64(112)83(132)105-55(19-10-11-31-88)77(126)108-62(40-67(91)116)76(125)99-45-71(120)111-33-14-22-65(111)86(135)136)101-69(118)43-96-68(117)42-97-75(124)59(36-49-15-6-4-7-16-49)106-82(131)61(39-52-41-94-46-100-52)102-70(119)44-98-84(133)73(48(3)113)110-79(128)57(28-30-72(121)122)104-81(130)60(37-50-17-8-5-9-18-50)107-78(127)56(20-12-32-95-87(92)93)103-74(123)54(89)27-29-66(90)115/h4-9,15-18,23-26,41,46-48,54-65,73,113-114H,10-14,19-22,27-40,42-45,88-89H2,1-3H3,(H2,90,115)(H2,91,116)(H,94,100)(H,96,117)(H,97,124)(H,98,133)(H,99,125)(H,101,118)(H,102,119)(H,103,123)(H,104,130)(H,105,132)(H,106,131)(H,107,127)(H,108,126)(H,109,129)(H,110,128)(H,121,122)(H,135,136)(H4,92,93,95)/t48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,73+/m1/s1 ACHPFSSODZFULV-YNSMZBETSA-N 50270974 (2S)-1-{2-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508704 IgG receptor FcRn large subunit p51 Homo sapiens 100000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270974&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935292 104116017 CHEMBL508704 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415474 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)34-57(79(128)108-62(37-50-22-24-52(113)25-23-50)84(133)111-33-12-20-63(111)82(131)104-54(18-10-30-87)76(125)107-61(39-66(90)115)75(124)98-44-70(119)110-32-13-21-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)58(35-48-14-6-4-7-15-48)105-81(130)60(38-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-78(127)56(27-29-71(120)121)103-80(129)59(36-49-16-8-5-9-17-49)106-77(126)55(19-11-31-94-86(91)92)102-73(122)53(88)26-28-65(89)114/h4-9,14-17,22-25,40,45-47,53-64,72,112-113H,10-13,18-21,26-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,129)(H,104,131)(H,105,130)(H,106,126)(H,107,125)(H,108,128)(H,109,127)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 QYCUXBLVBNBTGZ-JQYWQRDCSA-N 50270973 (2S)-1-{2-[(2S)-2-[(2S)-5-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL501283 IgG receptor FcRn large subunit p51 Homo sapiens 80000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270973&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935291 104116016 CHEMBL501283 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415475 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)33-56(78(127)107-61(36-49-20-22-51(112)23-21-49)83(132)110-32-11-18-62(110)81(130)103-55(28-29-86)76(125)106-60(38-65(89)114)74(123)97-43-69(118)109-31-12-19-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)57(34-47-13-6-4-7-14-47)104-80(129)59(37-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-77(126)54(25-27-70(119)120)102-79(128)58(35-48-15-8-5-9-16-48)105-75(124)53(17-10-30-93-85(90)91)101-72(121)52(87)24-26-64(88)113/h4-9,13-16,20-23,39,44-46,52-63,71,111-112H,10-12,17-19,24-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,128)(H,103,130)(H,104,129)(H,105,124)(H,106,125)(H,107,127)(H,108,126)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 DNGHQZAJUQMBNF-QZSPZITESA-N 50270972 (2S)-1-{2-[(2S)-2-[(2S)-4-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}butanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL503205 IgG receptor FcRn large subunit p51 Homo sapiens 86000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270972&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935290 104116015 CHEMBL503205 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415476 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)105-59(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)106-60(37-85)79(128)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-75(124)53(25-27-69(118)119)101-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-26-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,126)(H,102,127)(H,103,123)(H,104,128)(H,105,125)(H,106,129)(H,107,124)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 KBIMFOIIGNJKLI-AZARTFGISA-N 50270971 (2S)-1-{2-[(2S)-2-[(2S)-3-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-4-carboxybutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508491 IgG receptor FcRn large subunit p51 Homo sapiens 71000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270971&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935289 104116014 CHEMBL508491 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415477 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H123N25O24/c1-46(2)33-56(78(127)108-62(36-50-23-25-52(113)26-24-50)84(133)111-32-13-21-63(111)82(131)103-54(19-10-11-29-87)76(125)106-60(38-66(90)115)75(124)98-44-70(119)110-31-14-22-64(110)85(134)135)100-68(117)42-95-67(116)41-96-74(123)57(34-48-15-6-4-7-16-48)104-80(129)59(37-51-40-93-45-99-51)101-69(118)43-97-83(132)72(47(3)112)109-81(130)61(39-71(120)121)107-79(128)58(35-49-17-8-5-9-18-49)105-77(126)55(20-12-30-94-86(91)92)102-73(122)53(88)27-28-65(89)114/h4-9,15-18,23-26,40,45-47,53-64,72,112-113H,10-14,19-22,27-39,41-44,87-88H2,1-3H3,(H2,89,114)(H2,90,115)(H,93,99)(H,95,116)(H,96,123)(H,97,132)(H,98,124)(H,100,117)(H,101,118)(H,102,122)(H,103,131)(H,104,129)(H,105,126)(H,106,125)(H,107,128)(H,108,127)(H,109,130)(H,120,121)(H,134,135)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,72+/m1/s1 LWGWSFVMTWVAKK-JQYWQRDCSA-N 50270970 (2S)-1-{2-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL525624 IgG receptor FcRn large subunit p51 Homo sapiens 10000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270970&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935288 104116013 CHEMBL525624 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415478 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C85H121N25O24/c1-45(2)32-55(77(126)107-61(35-49-22-24-51(112)25-23-49)83(132)110-31-12-20-62(110)81(130)102-53(18-10-28-86)75(124)105-59(37-65(89)114)74(123)97-43-69(118)109-30-13-21-63(109)84(133)134)99-67(116)41-94-66(115)40-95-73(122)56(33-47-14-6-4-7-15-47)103-79(128)58(36-50-39-92-44-98-50)100-68(117)42-96-82(131)71(46(3)111)108-80(129)60(38-70(119)120)106-78(127)57(34-48-16-8-5-9-17-48)104-76(125)54(19-11-29-93-85(90)91)101-72(121)52(87)26-27-64(88)113/h4-9,14-17,22-25,39,44-46,52-63,71,111-112H,10-13,18-21,26-38,40-43,86-87H2,1-3H3,(H2,88,113)(H2,89,114)(H,92,98)(H,94,115)(H,95,122)(H,96,131)(H,97,123)(H,99,116)(H,100,117)(H,101,121)(H,102,130)(H,103,128)(H,104,125)(H,105,124)(H,106,127)(H,107,126)(H,108,129)(H,119,120)(H,133,134)(H4,90,91,93)/t46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,71+/m1/s1 CVZXHGRAETXFEG-QZSPZITESA-N 50270969 (2S)-1-{2-[(2S)-2-[(2S)-5-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL450322 IgG receptor FcRn large subunit p51 Homo sapiens 16000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270969&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935287 104116012 CHEMBL450322 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415479 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H119N25O24/c1-44(2)31-54(76(125)106-60(34-48-20-22-50(111)23-21-48)82(131)109-30-11-18-61(109)80(129)101-53(26-27-85)75(124)104-58(36-64(88)113)73(122)96-42-68(117)108-29-12-19-62(108)83(132)133)98-66(115)40-93-65(114)39-94-72(121)55(32-46-13-6-4-7-14-46)102-78(127)57(35-49-38-91-43-97-49)99-67(116)41-95-81(130)70(45(3)110)107-79(128)59(37-69(118)119)105-77(126)56(33-47-15-8-5-9-16-47)103-74(123)52(17-10-28-92-84(89)90)100-71(120)51(86)24-25-63(87)112/h4-9,13-16,20-23,38,43-45,51-62,70,110-111H,10-12,17-19,24-37,39-42,85-86H2,1-3H3,(H2,87,112)(H2,88,113)(H,91,97)(H,93,114)(H,94,121)(H,95,130)(H,96,122)(H,98,115)(H,99,116)(H,100,120)(H,101,129)(H,102,127)(H,103,123)(H,104,124)(H,105,126)(H,106,125)(H,107,128)(H,118,119)(H,132,133)(H4,89,90,92)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,70+/m1/s1 JSQQGMJNNNMSPR-AZARTFGISA-N 50270968 (2S)-1-{2-[(2S)-2-[(2S)-4-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}butanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL526130 IgG receptor FcRn large subunit p51 Homo sapiens 68000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270968&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935286 104116011 CHEMBL526130 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415480 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H117N25O24/c1-43(2)29-52(74(123)104-58(32-47-20-22-49(110)23-21-47)81(130)108-28-11-18-60(108)79(128)105-59(36-84)78(127)102-56(34-63(87)112)72(121)95-41-67(116)107-27-12-19-61(107)82(131)132)97-65(114)39-92-64(113)38-93-71(120)53(30-45-13-6-4-7-14-45)100-76(125)55(33-48-37-90-42-96-48)98-66(115)40-94-80(129)69(44(3)109)106-77(126)57(35-68(117)118)103-75(124)54(31-46-15-8-5-9-16-46)101-73(122)51(17-10-26-91-83(88)89)99-70(119)50(85)24-25-62(86)111/h4-9,13-16,20-23,37,42-44,50-61,69,109-110H,10-12,17-19,24-36,38-41,84-85H2,1-3H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,120)(H,94,129)(H,95,121)(H,97,114)(H,98,115)(H,99,119)(H,100,125)(H,101,122)(H,102,127)(H,103,124)(H,104,123)(H,105,128)(H,106,126)(H,117,118)(H,131,132)(H4,88,89,91)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,69+/m1/s1 IWVVFRAGJKNOTJ-YHTHZICESA-N 50270967 (2S)-1-{2-[(2S)-2-[(2S)-3-amino-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506740 IgG receptor FcRn large subunit p51 Homo sapiens 32000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270967&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935285 104116010 CHEMBL506740 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415481 CC(C)C[C@H](N(C)C(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C73H104N18O16S2/c1-41(2)31-56(66(101)85-53(34-45-24-26-47(93)27-25-45)70(105)91-30-16-23-55(91)65(100)86-54(39-108)71(106)107)89(6)58(95)38-90-29-14-13-22-49(69(90)104)82-62(97)50(32-43-17-9-7-10-18-43)84-63(98)52(35-46-36-77-40-80-46)81-57(94)37-79-67(102)59(42(3)92)87-68(103)60(73(4,5)109)88-64(99)51(33-44-19-11-8-12-20-44)83-61(96)48(74)21-15-28-78-72(75)76/h7-12,17-20,24-27,36,40-42,48-56,59-60,92-93,108-109H,13-16,21-23,28-35,37-39,74H2,1-6H3,(H,77,80)(H,79,102)(H,81,94)(H,82,97)(H,83,96)(H,84,98)(H,85,101)(H,86,100)(H,87,103)(H,88,99)(H,106,107)(H4,75,76,78)/t42-,48+,49-,50+,51+,52+,53+,54+,55+,56+,59+,60+/m1/s1 FWVGXRFGTDNWQB-NBXYRGRJSA-N 50270966 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxoazepan-1-yl]-N-methylacetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL526174 IgG receptor FcRn large subunit p51 Homo sapiens 620 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270966&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585846 104116009 CHEMBL526174 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415482 CC(C)C[C@H](N(C)C(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H102N18O16S2/c1-40(2)30-55(65(100)84-52(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-54(90)64(99)85-53(38-107)70(105)106)88(6)57(94)37-89-28-14-21-48(68(89)103)81-61(96)49(31-42-16-9-7-10-17-42)83-62(97)51(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)86-67(102)59(72(4,5)108)87-63(98)50(32-43-18-11-8-12-19-43)82-60(95)47(73)20-13-27-77-71(74)75/h7-12,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,13-15,20-22,27-34,36-38,73H2,1-6H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,95)(H,83,97)(H,84,100)(H,85,99)(H,86,102)(H,87,98)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1 ISEDOUIWHCJEGY-MDOMHRAVSA-N 50270965 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-2-oxopiperidin-1-yl]-N-methylacetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL500475 IgG receptor FcRn large subunit p51 Homo sapiens 530 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270965&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585845 104116008 CHEMBL500475 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415483 CC(C)C[C@H](NC(=O)[C@H]1CS[C@@H]2CC[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C72H100N18O16S3/c1-38(2)28-47(60(95)85-51(31-42-20-22-44(92)23-21-42)68(103)89-27-13-19-53(89)64(99)86-52(35-107)70(105)106)84-65(100)54-36-109-56-25-24-46(69(104)90(54)56)81-61(96)48(29-40-14-8-6-9-15-40)83-62(97)50(32-43-33-76-37-79-43)80-55(93)34-78-66(101)57(39(3)91)87-67(102)58(72(4,5)108)88-63(98)49(30-41-16-10-7-11-17-41)82-59(94)45(73)18-12-26-77-71(74)75/h6-11,14-17,20-23,33,37-39,45-54,56-58,91-92,107-108H,12-13,18-19,24-32,34-36,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,100)(H,85,95)(H,86,99)(H,87,102)(H,88,98)(H,105,106)(H4,74,75,77)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,54-,56-,57+,58+/m1/s1 ORMBSNDOGYKGRZ-PLGXUIQYSA-N 50270964 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R,8aR)-6-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-5-oxo-hexahydro-2H-pyrido[2,1-b][1,3]thiazol-3-yl]formamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL525583 IgG receptor FcRn large subunit p51 Homo sapiens 2200 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270964&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585844 104116007 CHEMBL525583 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415484 CC(C)C[C@H](NC(=O)[C@H]1CSC2C[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H98N18O16S3/c1-37(2)26-45(59(94)83-49(29-41-20-22-43(91)23-21-41)67(102)88-25-13-19-52(88)63(98)85-51(34-106)69(104)105)82-64(99)53-35-108-55-31-50(68(103)89(53)55)84-60(95)46(27-39-14-8-6-9-15-39)81-61(96)48(30-42-32-75-36-78-42)79-54(92)33-77-65(100)56(38(3)90)86-66(101)57(71(4,5)107)87-62(97)47(28-40-16-10-7-11-17-40)80-58(93)44(72)18-12-24-76-70(73)74/h6-11,14-17,20-23,32,36-38,44-53,55-57,90-91,106-107H,12-13,18-19,24-31,33-35,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,99)(H,83,94)(H,84,95)(H,85,98)(H,86,101)(H,87,97)(H,104,105)(H4,73,74,76)/t38-,44+,45+,46+,47+,48+,49+,50-,51+,52+,53-,55?,56+,57+/m1/s1 FEZKMFDXZVPPPA-VIMAYOAJSA-N 50270963 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R)-6-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazol-3-yl]formamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid hydrochloride::CHEMBL520698 IgG receptor FcRn large subunit p51 Homo sapiens 23000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270963&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585842 104116006 CHEMBL520698 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415485 CC(C)C[C@H](NC(=O)[C@H]1CSC2C[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H98N18O16S3/c1-37(2)26-45(59(94)83-49(29-41-20-22-43(91)23-21-41)67(102)88-25-13-19-52(88)63(98)85-51(34-106)69(104)105)82-64(99)53-35-108-55-31-50(68(103)89(53)55)84-60(95)46(27-39-14-8-6-9-15-39)81-61(96)48(30-42-32-75-36-78-42)79-54(92)33-77-65(100)56(38(3)90)86-66(101)57(71(4,5)107)87-62(97)47(28-40-16-10-7-11-17-40)80-58(93)44(72)18-12-24-76-70(73)74/h6-11,14-17,20-23,32,36-38,44-53,55-57,90-91,106-107H,12-13,18-19,24-31,33-35,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,99)(H,83,94)(H,84,95)(H,85,98)(H,86,101)(H,87,97)(H,104,105)(H4,73,74,76)/t38-,44+,45+,46+,47+,48+,49+,50-,51+,52+,53-,55?,56+,57+/m1/s1 FEZKMFDXZVPPPA-VIMAYOAJSA-N 50270962 (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R)-6-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]-5-oxo-hexahydropyrrolo[2,1-b][1,3]thiazol-3-yl]formamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid::CHEMBL504539 IgG receptor FcRn large subunit p51 Homo sapiens 13000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270962&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585842 104116005 CHEMBL504539 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415486 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-44(2)31-53(74(121)103-58(34-48-22-24-50(110)25-23-48)81(128)108-30-13-20-60(108)78(125)104-59(42-131)77(124)102-57(36-63(87)112)72(119)95-41-67(116)107-29-14-21-61(107)82(129)130)97-65(114)39-92-64(113)38-93-71(118)54(32-46-15-8-6-9-16-46)100-75(122)56(35-49-37-90-43-96-49)98-66(115)40-94-79(126)68(45(3)109)105-80(127)69(84(4,5)132)106-76(123)55(33-47-17-10-7-11-18-47)101-73(120)52(19-12-28-91-83(88)89)99-70(117)51(85)26-27-62(86)111/h6-11,15-18,22-25,37,43-45,51-61,68-69,109-110,131-132H,12-14,19-21,26-36,38-42,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,96)(H,92,113)(H,93,118)(H,94,126)(H,95,119)(H,97,114)(H,98,115)(H,99,117)(H,100,122)(H,101,120)(H,102,124)(H,103,121)(H,104,125)(H,105,127)(H,106,123)(H,129,130)(H4,88,89,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59-,60-,61+,68+,69+/m1/s1 XMBRKVYGPTUTDQ-PNQCIWQISA-N 50270903 (2S)-1-{2-[(2S)-2-[(2S)-2-{[(2R)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL524487 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270903&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935253 104115946 CHEMBL524487 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415487 CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C87H124N24O22S2/c1-46(2)34-55(76(123)105-60(37-50-24-26-52(113)27-25-50)84(131)111-33-14-22-63(111)81(128)106-61(44-134)79(126)103-59(39-66(90)115)74(121)97-43-69(118)110-32-15-23-64(110)85(132)133)104-80(127)62-21-13-31-109(62)68(117)42-96-73(120)56(35-48-16-8-6-9-17-48)101-77(124)58(38-51-40-93-45-98-51)99-67(116)41-95-82(129)70(47(3)112)107-83(130)71(87(4,5)135)108-78(125)57(36-49-18-10-7-11-19-49)102-75(122)54(20-12-30-94-86(91)92)100-72(119)53(88)28-29-65(89)114/h6-11,16-19,24-27,40,45-47,53-64,70-71,112-113,134-135H,12-15,20-23,28-39,41-44,88H2,1-5H3,(H2,89,114)(H2,90,115)(H,93,98)(H,95,129)(H,96,120)(H,97,121)(H,99,116)(H,100,119)(H,101,124)(H,102,122)(H,103,126)(H,104,127)(H,105,123)(H,106,128)(H,107,130)(H,108,125)(H,132,133)(H4,91,92,94)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62-,63+,64+,70+,71-/m1/s1 GRDKPLKVGVVKJL-QTLAHMFMSA-N 50270838 CHEMBL508564 IgG receptor FcRn large subunit p51 Homo sapiens 1400 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270838&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935219 104115900 CHEMBL508564 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415488 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O InChI=1S/C82H114N24O22S2/c1-43(2)29-52-73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)40-129-130-41-59(102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109)77(123)104-68(44(3)107)79(125)92-38-66(113)96-55(33-48-35-88-42-94-48)75(121)98-53(30-45-13-6-4-7-14-45)70(116)91-36-64(111)90-37-65(112)95-52/h4-9,13-16,20-23,35,42-44,50-61,68,107-108H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 BEWHODOAEGZIDE-YNALCKGOSA-N 50270783 CHEMBL508411::QRFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 36000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270783&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935178 104115845 CHEMBL508411 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415489 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O InChI=1S/C82H114N24O22S2/c1-43(2)29-52-73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)40-129-130-41-59(102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109)77(123)104-68(44(3)107)79(125)92-38-66(113)96-55(33-48-35-88-42-94-48)75(121)98-53(30-45-13-6-4-7-14-45)70(116)91-36-64(111)90-37-65(112)95-52/h4-9,13-16,20-23,35,42-44,50-61,68,107-108H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 BEWHODOAEGZIDE-YNALCKGOSA-N 50270783 CHEMBL508411::QRFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 5700 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270783&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935178 104115845 CHEMBL508411 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415490 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O InChI=1S/C82H114N24O22S2/c1-43(2)29-52-73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)40-129-130-41-59(102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109)77(123)104-68(44(3)107)79(125)92-38-66(113)96-55(33-48-35-88-42-94-48)75(121)98-53(30-45-13-6-4-7-14-45)70(116)91-36-64(111)90-37-65(112)95-52/h4-9,13-16,20-23,35,42-44,50-61,68,107-108H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 BEWHODOAEGZIDE-YNALCKGOSA-N 50270783 CHEMBL508411::QRFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 45000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270783&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935178 104115845 CHEMBL508411 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415491 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C66H92N18O16S2/c1-36(2)24-44(58(92)80-48(27-40-18-20-42(86)21-19-40)64(98)84-23-11-17-51(84)62(96)82-50(34-102)65(99)100)76-53(88)31-72-52(87)30-73-57(91)45(25-38-12-6-4-7-13-38)79-60(94)47(28-41-29-70-35-75-41)77-54(89)32-74-63(97)55(37(3)85)83-61(95)49(33-101)81-59(93)46(26-39-14-8-5-9-15-39)78-56(90)43(67)16-10-22-71-66(68)69/h4-9,12-15,18-21,29,35-37,43-51,55,85-86,101-102H,10-11,16-17,22-28,30-34,67H2,1-3H3,(H,70,75)(H,72,87)(H,73,91)(H,74,97)(H,76,88)(H,77,89)(H,78,90)(H,79,94)(H,80,92)(H,81,93)(H,82,96)(H,83,95)(H,99,100)(H4,68,69,71)/t37-,43+,44+,45+,46+,47+,48+,49+,50+,51+,55+/m1/s1 DXMDDJABZSEOKI-BUXVGQQFSA-N 50270797 CHEMBL505689::RFCTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 87000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270797&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585688 104115859 CHEMBL505689 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415492 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C75H107N23O19S2/c1-39(2)26-49(67(110)94-53(29-43-18-20-45(100)21-19-43)74(117)98-25-11-17-56(98)72(115)96-54(36-118)70(113)91-48(63(79)106)31-58(78)102)88-60(104)34-84-59(103)33-85-65(108)50(27-41-12-6-4-7-13-41)92-69(112)52(30-44-32-82-38-87-44)89-61(105)35-86-73(116)62(40(3)99)97-71(114)55(37-119)95-68(111)51(28-42-14-8-5-9-15-42)93-66(109)47(16-10-24-83-75(80)81)90-64(107)46(76)22-23-57(77)101/h4-9,12-15,18-21,32,38-40,46-56,62,99-100,118-119H,10-11,16-17,22-31,33-37,76H2,1-3H3,(H2,77,101)(H2,78,102)(H2,79,106)(H,82,87)(H,84,103)(H,85,108)(H,86,116)(H,88,104)(H,89,105)(H,90,107)(H,91,113)(H,92,112)(H,93,109)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H4,80,81,83)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,62+/m1/s1 KGWSPAXUBOZHGD-UDZGLHSYSA-N 50270796 CHEMBL524509::QRFCTGHFGGLYPCN IgG receptor FcRn large subunit p51 Homo sapiens 31000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270796&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935184 104115858 CHEMBL524509 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415493 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(O)=O InChI=1S/C77H109N23O21S2/c1-40(2)26-49(69(114)96-54(29-44-18-20-46(102)21-19-44)76(121)100-25-11-17-57(100)74(119)98-55(37-122)72(117)95-53(31-59(80)104)67(112)88-36-63(108)109)90-61(106)34-85-60(105)33-86-66(111)50(27-42-12-6-4-7-13-42)93-71(116)52(30-45-32-83-39-89-45)91-62(107)35-87-75(120)64(41(3)101)99-73(118)56(38-123)97-70(115)51(28-43-14-8-5-9-15-43)94-68(113)48(16-10-24-84-77(81)82)92-65(110)47(78)22-23-58(79)103/h4-9,12-15,18-21,32,39-41,47-57,64,101-102,122-123H,10-11,16-17,22-31,33-38,78H2,1-3H3,(H2,79,103)(H2,80,104)(H,83,89)(H,85,105)(H,86,111)(H,87,120)(H,88,112)(H,90,106)(H,91,107)(H,92,110)(H,93,116)(H,94,113)(H,95,117)(H,96,114)(H,97,115)(H,98,119)(H,99,118)(H,108,109)(H4,81,82,84)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,64+/m1/s1 LRHRRCBDEMECGP-MHJZOWPKSA-N 50270795 CHEMBL503730::QRFCTGHFGGLYPCNG IgG receptor FcRn large subunit p51 Homo sapiens 34000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270795&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935183 104115857 CHEMBL503730 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415494 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C71H96N18O19S2/c1-38(2)24-46(64(100)84-50(27-42-18-20-44(91)21-19-42)70(106)89-23-10-16-53(89)68(104)86-51(35-109)66(102)83-49(29-55(73)92)63(99)78-34-59(96)88-22-11-17-54(88)71(107)108)80-57(94)32-75-56(93)31-76-62(98)47(26-41-14-8-5-9-15-41)82-65(101)48(28-43-30-74-37-79-43)81-58(95)33-77-69(105)60(39(3)90)87-67(103)52(36-110)85-61(97)45(72)25-40-12-6-4-7-13-40/h4-9,12-15,18-21,30,37-39,45-54,60,90-91,109-110H,10-11,16-17,22-29,31-36,72H2,1-3H3,(H2,73,92)(H,74,79)(H,75,93)(H,76,98)(H,77,105)(H,78,99)(H,80,94)(H,81,95)(H,82,101)(H,83,102)(H,84,100)(H,85,97)(H,86,104)(H,87,103)(H,107,108)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,60+/m1/s1 APVKOCLSIOQKDG-HHJBWFGZSA-N 50270794 CHEMBL526683::FCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 67000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270794&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585685 104115856 CHEMBL526683 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415495 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C77H108N22O20S2/c1-41(2)27-49(68(110)94-54(30-45-20-22-47(101)23-21-45)75(117)99-26-11-18-57(99)73(115)96-55(38-120)71(113)93-53(32-59(79)102)67(109)87-37-63(106)98-25-12-19-58(98)76(118)119)89-61(104)35-84-60(103)34-85-66(108)50(28-43-13-6-4-7-14-43)92-70(112)52(31-46-33-82-40-88-46)90-62(105)36-86-74(116)64(42(3)100)97-72(114)56(39-121)95-69(111)51(29-44-15-8-5-9-16-44)91-65(107)48(78)17-10-24-83-77(80)81/h4-9,13-16,20-23,33,40-42,48-58,64,100-101,120-121H,10-12,17-19,24-32,34-39,78H2,1-3H3,(H2,79,102)(H,82,88)(H,84,103)(H,85,108)(H,86,116)(H,87,109)(H,89,104)(H,90,105)(H,91,107)(H,92,112)(H,93,113)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H,118,119)(H4,80,81,83)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,64+/m1/s1 ROKRSOUEQCXSBS-KRWRJSNHSA-N 50270793 CHEMBL207341::RFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 24000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270793&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935182 104115855 CHEMBL207341 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415496 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C45H61N11O12/c1-25(2)16-31(41(63)55-34(18-28-11-13-30(58)14-12-28)44(66)56-15-7-10-35(56)45(67)68)52-37(60)22-48-36(59)21-49-40(62)32(17-27-8-5-4-6-9-27)54-42(64)33(19-29-20-47-24-51-29)53-38(61)23-50-43(65)39(46)26(3)57/h4-6,8-9,11-14,20,24-26,31-35,39,57-58H,7,10,15-19,21-23,46H2,1-3H3,(H,47,51)(H,48,59)(H,49,62)(H,50,65)(H,52,60)(H,53,61)(H,54,64)(H,55,63)(H,67,68)/t26-,31+,32+,33+,34+,35+,39+/m1/s1 IWERDNJEWHQVRC-WZVNFFMFSA-N 50270792 CHEMBL498954::TGHFGGLYP IgG receptor FcRn large subunit p51 Homo sapiens >250000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270792&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585683 104115854 CHEMBL498954 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415497 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C51H71N13O14S2/c1-27(2)16-34(46(72)61-37(18-30-11-13-32(66)14-12-30)50(76)64-15-7-10-39(64)48(74)62-38(25-80)51(77)78)58-41(68)22-54-40(67)21-55-45(71)35(17-29-8-5-4-6-9-29)60-47(73)36(19-31-20-53-26-57-31)59-42(69)23-56-49(75)43(28(3)65)63-44(70)33(52)24-79/h4-6,8-9,11-14,20,26-28,33-39,43,65-66,79-80H,7,10,15-19,21-25,52H2,1-3H3,(H,53,57)(H,54,67)(H,55,71)(H,56,75)(H,58,68)(H,59,69)(H,60,73)(H,61,72)(H,62,74)(H,63,70)(H,77,78)/t28-,33+,34+,35+,36+,37+,38+,39+,43+/m1/s1 AKRMQAGRXYORLC-VIVXVWMSSA-N 50270791 CHEMBL444514::CTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 110000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270791&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585682 104115853 CHEMBL444514 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415498 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N20O18S2/c1-38(2)26-47(63(101)87-51(29-42-18-20-44(93)21-19-42)69(107)91-25-11-17-54(91)67(105)89-53(36-111)70(108)109)82-57(96)33-78-56(95)32-79-61(99)48(27-40-12-6-4-7-13-40)85-65(103)50(30-43-31-76-37-81-43)83-58(97)34-80-68(106)59(39(3)92)90-66(104)52(35-110)88-64(102)49(28-41-14-8-5-9-15-41)86-62(100)46(16-10-24-77-71(74)75)84-60(98)45(72)22-23-55(73)94/h4-9,12-15,18-21,31,37-39,45-54,59,92-93,110-111H,10-11,16-17,22-30,32-36,72H2,1-3H3,(H2,73,94)(H,76,81)(H,78,95)(H,79,99)(H,80,106)(H,82,96)(H,83,97)(H,84,98)(H,85,103)(H,86,100)(H,87,101)(H,88,102)(H,89,105)(H,90,104)(H,108,109)(H4,74,75,77)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+/m1/s1 XFKSGNARKLOKSR-GVCIWFFJSA-N 50270790 CHEMBL451944::QRFCTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 27000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270790&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935181 104115852 CHEMBL451944 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415499 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C62H87N17O18S2/c1-32(2)19-39(71-49(84)26-66-48(83)25-67-54(88)40(20-34-9-5-4-6-10-34)73-57(91)41(22-36-24-65-31-70-36)72-50(85)27-68-60(94)52(33(3)80)77-53(87)38(63)29-98)56(90)75-43(21-35-13-15-37(81)16-14-35)61(95)79-18-7-11-45(79)59(93)76-44(30-99)58(92)74-42(23-47(64)82)55(89)69-28-51(86)78-17-8-12-46(78)62(96)97/h4-6,9-10,13-16,24,31-33,38-46,52,80-81,98-99H,7-8,11-12,17-23,25-30,63H2,1-3H3,(H2,64,82)(H,65,70)(H,66,83)(H,67,88)(H,68,94)(H,69,89)(H,71,84)(H,72,85)(H,73,91)(H,74,92)(H,75,90)(H,76,93)(H,77,87)(H,96,97)/t33-,38+,39+,40+,41+,42+,43+,44+,45+,46+,52+/m1/s1 UPRUYQIHZLOAQI-RMCLFBFUSA-N 50270789 CHEMBL525216::CTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 239000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270789&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585680 104115851 CHEMBL525216 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415500 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-YNALCKGOSA-N 50270788 CHEMBL506507::QRFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 40000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270788&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935180 104115850 CHEMBL506507 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415501 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)NCC(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C86H118N26O21S2/c1-47(2)31-57(75(123)109-62(84(132)133)35-50-19-10-5-11-20-50)105-76(124)60(34-51-24-26-53(114)27-25-51)108-80(128)64-44-134-135-45-65(111-77(125)59(33-49-17-8-4-9-18-49)107-79(127)63(43-113)110-72(120)54(87)37-67(88)115)81(129)104-55(21-12-28-94-85(89)90)73(121)98-41-70(118)101-56(22-13-29-95-86(91)92)83(131)112-30-14-23-66(112)82(130)99-42-71(119)102-61(36-52-38-93-46-100-52)78(126)106-58(32-48-15-6-3-7-16-48)74(122)97-39-68(116)96-40-69(117)103-64/h3-11,15-20,24-27,38,46-47,54-66,113-114H,12-14,21-23,28-37,39-45,87H2,1-2H3,(H2,88,115)(H,93,100)(H,96,116)(H,97,122)(H,98,121)(H,99,130)(H,101,118)(H,102,119)(H,103,117)(H,104,129)(H,105,124)(H,106,126)(H,107,127)(H,108,128)(H,109,123)(H,110,120)(H,111,125)(H,132,133)(H4,89,90,94)(H4,91,92,95)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m0/s1 DXRJJIPQJUARAV-SZMGYULJSA-N 50270787 CHEMBL509774::NSFCRGRPGHFGGCYLF IgG receptor FcRn large subunit p51 Homo sapiens 33000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270787&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935179 104115849 CHEMBL509774 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415502 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)[C@@H](C)CC InChI=1S/C85H118N20O26S2/c1-8-42(4)68-82(127)98-56(31-48-20-24-51(108)25-21-48)77(122)101-61(80(125)96-54(29-46-15-12-11-13-16-46)75(120)97-58(33-63(86)109)74(119)92-45(7)85(130)131)39-132-133-40-62(102-76(121)55(30-47-18-22-50(107)23-19-47)95-79(124)60(38-106)100-73(118)52-17-14-28-88-52)81(126)105-69(43(5)9-2)83(128)94-53(26-27-66(112)113)71(116)89-36-64(110)93-57(32-49-35-87-41-91-49)78(123)104-70(44(6)10-3)84(129)99-59(34-67(114)115)72(117)90-37-65(111)103-68/h11-13,15-16,18-25,35,41-45,52-62,68-70,88,106-108H,8-10,14,17,26-34,36-40H2,1-7H3,(H2,86,109)(H,87,91)(H,89,116)(H,90,117)(H,92,119)(H,93,110)(H,94,128)(H,95,124)(H,96,125)(H,97,120)(H,98,127)(H,99,129)(H,100,118)(H,101,122)(H,102,121)(H,103,111)(H,104,123)(H,105,126)(H,112,113)(H,114,115)(H,130,131)/t42-,43-,44-,45-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-,69-,70-/m0/s1 IQARFOIQUSLJBV-HFVQQTQISA-N 50270786 CHEMBL501558::PSYCIEGHIDGIYCFNA IgG receptor FcRn large subunit p51 Homo sapiens 49000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270786&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585677 104115848 CHEMBL501558 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415503 CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C80H122N22O21S3/c1-6-44(3)66(101-78(120)67(45(4)7-2)100-68(110)50(83)18-11-13-28-81)77(119)99-59-42-126-125-41-58(74(116)94-51(25-26-61(84)105)69(111)88-38-64(108)92-53(80(122)123)19-12-14-29-82)98-72(114)55(33-47-21-23-49(104)24-22-47)96-71(113)52(27-31-124-5)91-63(107)37-86-62(106)36-87-70(112)54(32-46-16-9-8-10-17-46)95-73(115)56(34-48-35-85-43-90-48)93-65(109)39-89-76(118)60-20-15-30-102(60)79(121)57(40-103)97-75(59)117/h8-10,16-17,21-24,35,43-45,50-60,66-67,103-104H,6-7,11-15,18-20,25-34,36-42,81-83H2,1-5H3,(H2,84,105)(H,85,90)(H,86,106)(H,87,112)(H,88,111)(H,89,118)(H,91,107)(H,92,108)(H,93,109)(H,94,116)(H,95,115)(H,96,113)(H,97,117)(H,98,114)(H,99,119)(H,100,110)(H,101,120)(H,122,123)/t44-,45-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,66-,67-/m0/s1 PTIKFFAQESKEGS-RLYKKVSASA-N 50270785 CHEMBL503219::KIICSPGHFGGMYCQGK IgG receptor FcRn large subunit p51 Homo sapiens 64000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270785&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585676 104115847 CHEMBL503219 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415504 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@H](C)O InChI=1S/C75H103N21O23S2/c1-6-38(4)63-74(117)92-49(24-42-14-18-45(99)19-15-42)67(110)93-53(70(113)91-51(26-55(78)101)69(112)90-48(23-41-12-16-44(98)17-13-41)66(109)88-46(75(118)119)20-21-54(77)100)35-121-120-34-52(87-59(105)31-81-57(103)29-80-56(102)27-76)71(114)95-62(37(2)3)73(116)96-64(39(5)97)72(115)84-33-60(106)86-50(25-43-28-79-36-85-43)68(111)89-47(22-40-10-8-7-9-11-40)65(108)83-30-58(104)82-32-61(107)94-63/h7-19,28,36-39,46-53,62-64,97-99H,6,20-27,29-35,76H2,1-5H3,(H2,77,100)(H2,78,101)(H,79,85)(H,80,102)(H,81,103)(H,82,104)(H,83,108)(H,84,115)(H,86,106)(H,87,105)(H,88,109)(H,89,111)(H,90,112)(H,91,113)(H,92,117)(H,93,110)(H,94,107)(H,95,114)(H,96,116)(H,118,119)/t38-,39-,46-,47-,48-,49-,50-,51-,52-,53-,62-,63-,64-/m0/s1 RNDLHDADENIYQB-PYKOPHRNSA-N 50270784 CHEMBL499790::GGGCVTGHFGGIYCNYQ IgG receptor FcRn large subunit p51 Homo sapiens 33000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270784&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585675 104115846 CHEMBL499790 C02716 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415505 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C66H92N18O16S2/c1-36(2)24-44(58(92)80-48(27-40-18-20-42(86)21-19-40)64(98)84-23-11-17-51(84)62(96)82-50(34-102)65(99)100)76-53(88)31-72-52(87)30-73-57(91)45(25-38-12-6-4-7-13-38)79-60(94)47(28-41-29-70-35-75-41)77-54(89)32-74-63(97)55(37(3)85)83-61(95)49(33-101)81-59(93)46(26-39-14-8-5-9-15-39)78-56(90)43(67)16-10-22-71-66(68)69/h4-9,12-15,18-21,29,35-37,43-51,55,85-86,101-102H,10-11,16-17,22-28,30-34,67H2,1-3H3,(H,70,75)(H,72,87)(H,73,91)(H,74,97)(H,76,88)(H,77,89)(H,78,90)(H,79,94)(H,80,92)(H,81,93)(H,82,96)(H,83,95)(H,99,100)(H4,68,69,71)/t37-,43+,44+,45+,46+,47+,48+,49+,50+,51+,55+/m1/s1 DXMDDJABZSEOKI-BUXVGQQFSA-N 50270797 CHEMBL505689::RFCTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 10000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270797&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585688 104115859 CHEMBL505689 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415506 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C75H107N23O19S2/c1-39(2)26-49(67(110)94-53(29-43-18-20-45(100)21-19-43)74(117)98-25-11-17-56(98)72(115)96-54(36-118)70(113)91-48(63(79)106)31-58(78)102)88-60(104)34-84-59(103)33-85-65(108)50(27-41-12-6-4-7-13-41)92-69(112)52(30-44-32-82-38-87-44)89-61(105)35-86-73(116)62(40(3)99)97-71(114)55(37-119)95-68(111)51(28-42-14-8-5-9-15-42)93-66(109)47(16-10-24-83-75(80)81)90-64(107)46(76)22-23-57(77)101/h4-9,12-15,18-21,32,38-40,46-56,62,99-100,118-119H,10-11,16-17,22-31,33-37,76H2,1-3H3,(H2,77,101)(H2,78,102)(H2,79,106)(H,82,87)(H,84,103)(H,85,108)(H,86,116)(H,88,104)(H,89,105)(H,90,107)(H,91,113)(H,92,112)(H,93,109)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H4,80,81,83)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,62+/m1/s1 KGWSPAXUBOZHGD-UDZGLHSYSA-N 50270796 CHEMBL524509::QRFCTGHFGGLYPCN IgG receptor FcRn large subunit p51 Homo sapiens 6100 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270796&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935184 104115858 CHEMBL524509 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415507 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(O)=O InChI=1S/C77H109N23O21S2/c1-40(2)26-49(69(114)96-54(29-44-18-20-46(102)21-19-44)76(121)100-25-11-17-57(100)74(119)98-55(37-122)72(117)95-53(31-59(80)104)67(112)88-36-63(108)109)90-61(106)34-85-60(105)33-86-66(111)50(27-42-12-6-4-7-13-42)93-71(116)52(30-45-32-83-39-89-45)91-62(107)35-87-75(120)64(41(3)101)99-73(118)56(38-123)97-70(115)51(28-43-14-8-5-9-15-43)94-68(113)48(16-10-24-84-77(81)82)92-65(110)47(78)22-23-58(79)103/h4-9,12-15,18-21,32,39-41,47-57,64,101-102,122-123H,10-11,16-17,22-31,33-38,78H2,1-3H3,(H2,79,103)(H2,80,104)(H,83,89)(H,85,105)(H,86,111)(H,87,120)(H,88,112)(H,90,106)(H,91,107)(H,92,110)(H,93,116)(H,94,113)(H,95,117)(H,96,114)(H,97,115)(H,98,119)(H,99,118)(H,108,109)(H4,81,82,84)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,64+/m1/s1 LRHRRCBDEMECGP-MHJZOWPKSA-N 50270795 CHEMBL503730::QRFCTGHFGGLYPCNG IgG receptor FcRn large subunit p51 Homo sapiens 4600 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270795&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935183 104115857 CHEMBL503730 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415508 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C71H96N18O19S2/c1-38(2)24-46(64(100)84-50(27-42-18-20-44(91)21-19-42)70(106)89-23-10-16-53(89)68(104)86-51(35-109)66(102)83-49(29-55(73)92)63(99)78-34-59(96)88-22-11-17-54(88)71(107)108)80-57(94)32-75-56(93)31-76-62(98)47(26-41-14-8-5-9-15-41)82-65(101)48(28-43-30-74-37-79-43)81-58(95)33-77-69(105)60(39(3)90)87-67(103)52(36-110)85-61(97)45(72)25-40-12-6-4-7-13-40/h4-9,12-15,18-21,30,37-39,45-54,60,90-91,109-110H,10-11,16-17,22-29,31-36,72H2,1-3H3,(H2,73,92)(H,74,79)(H,75,93)(H,76,98)(H,77,105)(H,78,99)(H,80,94)(H,81,95)(H,82,101)(H,83,102)(H,84,100)(H,85,97)(H,86,104)(H,87,103)(H,107,108)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,60+/m1/s1 APVKOCLSIOQKDG-HHJBWFGZSA-N 50270794 CHEMBL526683::FCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 11000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270794&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585685 104115856 CHEMBL526683 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415509 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C77H108N22O20S2/c1-41(2)27-49(68(110)94-54(30-45-20-22-47(101)23-21-45)75(117)99-26-11-18-57(99)73(115)96-55(38-120)71(113)93-53(32-59(79)102)67(109)87-37-63(106)98-25-12-19-58(98)76(118)119)89-61(104)35-84-60(103)34-85-66(108)50(28-43-13-6-4-7-14-43)92-70(112)52(31-46-33-82-40-88-46)90-62(105)36-86-74(116)64(42(3)100)97-72(114)56(39-121)95-69(111)51(29-44-15-8-5-9-16-44)91-65(107)48(78)17-10-24-83-77(80)81/h4-9,13-16,20-23,33,40-42,48-58,64,100-101,120-121H,10-12,17-19,24-32,34-39,78H2,1-3H3,(H2,79,102)(H,82,88)(H,84,103)(H,85,108)(H,86,116)(H,87,109)(H,89,104)(H,90,105)(H,91,107)(H,92,112)(H,93,113)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H,118,119)(H4,80,81,83)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,64+/m1/s1 ROKRSOUEQCXSBS-KRWRJSNHSA-N 50270793 CHEMBL207341::RFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 2900 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270793&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935182 104115855 CHEMBL207341 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415510 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C45H61N11O12/c1-25(2)16-31(41(63)55-34(18-28-11-13-30(58)14-12-28)44(66)56-15-7-10-35(56)45(67)68)52-37(60)22-48-36(59)21-49-40(62)32(17-27-8-5-4-6-9-27)54-42(64)33(19-29-20-47-24-51-29)53-38(61)23-50-43(65)39(46)26(3)57/h4-6,8-9,11-14,20,24-26,31-35,39,57-58H,7,10,15-19,21-23,46H2,1-3H3,(H,47,51)(H,48,59)(H,49,62)(H,50,65)(H,52,60)(H,53,61)(H,54,64)(H,55,63)(H,67,68)/t26-,31+,32+,33+,34+,35+,39+/m1/s1 IWERDNJEWHQVRC-WZVNFFMFSA-N 50270792 CHEMBL498954::TGHFGGLYP IgG receptor FcRn large subunit p51 Homo sapiens >250000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270792&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585683 104115854 CHEMBL498954 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415511 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C51H71N13O14S2/c1-27(2)16-34(46(72)61-37(18-30-11-13-32(66)14-12-30)50(76)64-15-7-10-39(64)48(74)62-38(25-80)51(77)78)58-41(68)22-54-40(67)21-55-45(71)35(17-29-8-5-4-6-9-29)60-47(73)36(19-31-20-53-26-57-31)59-42(69)23-56-49(75)43(28(3)65)63-44(70)33(52)24-79/h4-6,8-9,11-14,20,26-28,33-39,43,65-66,79-80H,7,10,15-19,21-25,52H2,1-3H3,(H,53,57)(H,54,67)(H,55,71)(H,56,75)(H,58,68)(H,59,69)(H,60,73)(H,61,72)(H,62,74)(H,63,70)(H,77,78)/t28-,33+,34+,35+,36+,37+,38+,39+,43+/m1/s1 AKRMQAGRXYORLC-VIVXVWMSSA-N 50270791 CHEMBL444514::CTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 20000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270791&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585682 104115853 CHEMBL444514 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415512 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O InChI=1S/C71H100N20O18S2/c1-38(2)26-47(63(101)87-51(29-42-18-20-44(93)21-19-42)69(107)91-25-11-17-54(91)67(105)89-53(36-111)70(108)109)82-57(96)33-78-56(95)32-79-61(99)48(27-40-12-6-4-7-13-40)85-65(103)50(30-43-31-76-37-81-43)83-58(97)34-80-68(106)59(39(3)92)90-66(104)52(35-110)88-64(102)49(28-41-14-8-5-9-15-41)86-62(100)46(16-10-24-77-71(74)75)84-60(98)45(72)22-23-55(73)94/h4-9,12-15,18-21,31,37-39,45-54,59,92-93,110-111H,10-11,16-17,22-30,32-36,72H2,1-3H3,(H2,73,94)(H,76,81)(H,78,95)(H,79,99)(H,80,106)(H,82,96)(H,83,97)(H,84,98)(H,85,103)(H,86,100)(H,87,101)(H,88,102)(H,89,105)(H,90,104)(H,108,109)(H4,74,75,77)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+/m1/s1 XFKSGNARKLOKSR-GVCIWFFJSA-N 50270790 CHEMBL451944::QRFCTGHFGGLYPC IgG receptor FcRn large subunit p51 Homo sapiens 4200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270790&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935181 104115852 CHEMBL451944 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415513 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C62H87N17O18S2/c1-32(2)19-39(71-49(84)26-66-48(83)25-67-54(88)40(20-34-9-5-4-6-10-34)73-57(91)41(22-36-24-65-31-70-36)72-50(85)27-68-60(94)52(33(3)80)77-53(87)38(63)29-98)56(90)75-43(21-35-13-15-37(81)16-14-35)61(95)79-18-7-11-45(79)59(93)76-44(30-99)58(92)74-42(23-47(64)82)55(89)69-28-51(86)78-17-8-12-46(78)62(96)97/h4-6,9-10,13-16,24,31-33,38-46,52,80-81,98-99H,7-8,11-12,17-23,25-30,63H2,1-3H3,(H2,64,82)(H,65,70)(H,66,83)(H,67,88)(H,68,94)(H,69,89)(H,71,84)(H,72,85)(H,73,91)(H,74,92)(H,75,90)(H,76,93)(H,77,87)(H,96,97)/t33-,38+,39+,40+,41+,42+,43+,44+,45+,46+,52+/m1/s1 UPRUYQIHZLOAQI-RMCLFBFUSA-N 50270789 CHEMBL525216::CTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 34000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270789&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585680 104115851 CHEMBL525216 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415514 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1 HXEMPVGWOUNUGN-YNALCKGOSA-N 50270788 CHEMBL506507::QRFCTGHFGGLYPCNGP IgG receptor FcRn large subunit p51 Homo sapiens 5100 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270788&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935180 104115850 CHEMBL506507 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415515 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)NCC(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C86H118N26O21S2/c1-47(2)31-57(75(123)109-62(84(132)133)35-50-19-10-5-11-20-50)105-76(124)60(34-51-24-26-53(114)27-25-51)108-80(128)64-44-134-135-45-65(111-77(125)59(33-49-17-8-4-9-18-49)107-79(127)63(43-113)110-72(120)54(87)37-67(88)115)81(129)104-55(21-12-28-94-85(89)90)73(121)98-41-70(118)101-56(22-13-29-95-86(91)92)83(131)112-30-14-23-66(112)82(130)99-42-71(119)102-61(36-52-38-93-46-100-52)78(126)106-58(32-48-15-6-3-7-16-48)74(122)97-39-68(116)96-40-69(117)103-64/h3-11,15-20,24-27,38,46-47,54-66,113-114H,12-14,21-23,28-37,39-45,87H2,1-2H3,(H2,88,115)(H,93,100)(H,96,116)(H,97,122)(H,98,121)(H,99,130)(H,101,118)(H,102,119)(H,103,117)(H,104,129)(H,105,124)(H,106,126)(H,107,127)(H,108,128)(H,109,123)(H,110,120)(H,111,125)(H,132,133)(H4,89,90,94)(H4,91,92,95)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m0/s1 DXRJJIPQJUARAV-SZMGYULJSA-N 50270787 CHEMBL509774::NSFCRGRPGHFGGCYLF IgG receptor FcRn large subunit p51 Homo sapiens 9400 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270787&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935179 104115849 CHEMBL509774 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415516 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)[C@@H](C)CC InChI=1S/C85H118N20O26S2/c1-8-42(4)68-82(127)98-56(31-48-20-24-51(108)25-21-48)77(122)101-61(80(125)96-54(29-46-15-12-11-13-16-46)75(120)97-58(33-63(86)109)74(119)92-45(7)85(130)131)39-132-133-40-62(102-76(121)55(30-47-18-22-50(107)23-19-47)95-79(124)60(38-106)100-73(118)52-17-14-28-88-52)81(126)105-69(43(5)9-2)83(128)94-53(26-27-66(112)113)71(116)89-36-64(110)93-57(32-49-35-87-41-91-49)78(123)104-70(44(6)10-3)84(129)99-59(34-67(114)115)72(117)90-37-65(111)103-68/h11-13,15-16,18-25,35,41-45,52-62,68-70,88,106-108H,8-10,14,17,26-34,36-40H2,1-7H3,(H2,86,109)(H,87,91)(H,89,116)(H,90,117)(H,92,119)(H,93,110)(H,94,128)(H,95,124)(H,96,125)(H,97,120)(H,98,127)(H,99,129)(H,100,118)(H,101,122)(H,102,121)(H,103,111)(H,104,123)(H,105,126)(H,112,113)(H,114,115)(H,130,131)/t42-,43-,44-,45-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-,69-,70-/m0/s1 IQARFOIQUSLJBV-HFVQQTQISA-N 50270786 CHEMBL501558::PSYCIEGHIDGIYCFNA IgG receptor FcRn large subunit p51 Homo sapiens 8800 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270786&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585677 104115848 CHEMBL501558 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415517 CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C80H122N22O21S3/c1-6-44(3)66(101-78(120)67(45(4)7-2)100-68(110)50(83)18-11-13-28-81)77(119)99-59-42-126-125-41-58(74(116)94-51(25-26-61(84)105)69(111)88-38-64(108)92-53(80(122)123)19-12-14-29-82)98-72(114)55(33-47-21-23-49(104)24-22-47)96-71(113)52(27-31-124-5)91-63(107)37-86-62(106)36-87-70(112)54(32-46-16-9-8-10-17-46)95-73(115)56(34-48-35-85-43-90-48)93-65(109)39-89-76(118)60-20-15-30-102(60)79(121)57(40-103)97-75(59)117/h8-10,16-17,21-24,35,43-45,50-60,66-67,103-104H,6-7,11-15,18-20,25-34,36-42,81-83H2,1-5H3,(H2,84,105)(H,85,90)(H,86,106)(H,87,112)(H,88,111)(H,89,118)(H,91,107)(H,92,108)(H,93,109)(H,94,116)(H,95,115)(H,96,113)(H,97,117)(H,98,114)(H,99,119)(H,100,110)(H,101,120)(H,122,123)/t44-,45-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,66-,67-/m0/s1 PTIKFFAQESKEGS-RLYKKVSASA-N 50270785 CHEMBL503219::KIICSPGHFGGMYCQGK IgG receptor FcRn large subunit p51 Homo sapiens 22000 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270785&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585676 104115847 CHEMBL503219 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415518 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@H](C)O InChI=1S/C75H103N21O23S2/c1-6-38(4)63-74(117)92-49(24-42-14-18-45(99)19-15-42)67(110)93-53(70(113)91-51(26-55(78)101)69(112)90-48(23-41-12-16-44(98)17-13-41)66(109)88-46(75(118)119)20-21-54(77)100)35-121-120-34-52(87-59(105)31-81-57(103)29-80-56(102)27-76)71(114)95-62(37(2)3)73(116)96-64(39(5)97)72(115)84-33-60(106)86-50(25-43-28-79-36-85-43)68(111)89-47(22-40-10-8-7-9-11-40)65(108)83-30-58(104)82-32-61(107)94-63/h7-19,28,36-39,46-53,62-64,97-99H,6,20-27,29-35,76H2,1-5H3,(H2,77,100)(H2,78,101)(H,79,85)(H,80,102)(H,81,103)(H,82,104)(H,83,108)(H,84,115)(H,86,106)(H,87,105)(H,88,109)(H,89,111)(H,90,112)(H,91,113)(H,92,117)(H,93,110)(H,94,107)(H,95,114)(H,96,116)(H,118,119)/t38-,39-,46-,47-,48-,49-,50-,51-,52-,53-,62-,63-,64-/m0/s1 RNDLHDADENIYQB-PYKOPHRNSA-N 50270784 CHEMBL499790::GGGCVTGHFGGIYCNYQ IgG receptor FcRn large subunit p51 Homo sapiens 5200 6 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270784&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585675 104115846 CHEMBL499790 C02716 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415519 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)NCC(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C86H118N26O21S2/c1-47(2)31-57(75(123)109-62(84(132)133)35-50-19-10-5-11-20-50)105-76(124)60(34-51-24-26-53(114)27-25-51)108-80(128)64-44-134-135-45-65(111-77(125)59(33-49-17-8-4-9-18-49)107-79(127)63(43-113)110-72(120)54(87)37-67(88)115)81(129)104-55(21-12-28-94-85(89)90)73(121)98-41-70(118)101-56(22-13-29-95-86(91)92)83(131)112-30-14-23-66(112)82(130)99-42-71(119)102-61(36-52-38-93-46-100-52)78(126)106-58(32-48-15-6-3-7-16-48)74(122)97-39-68(116)96-40-69(117)103-64/h3-11,15-20,24-27,38,46-47,54-66,113-114H,12-14,21-23,28-37,39-45,87H2,1-2H3,(H2,88,115)(H,93,100)(H,96,116)(H,97,122)(H,98,121)(H,99,130)(H,101,118)(H,102,119)(H,103,117)(H,104,129)(H,105,124)(H,106,126)(H,107,127)(H,108,128)(H,109,123)(H,110,120)(H,111,125)(H,132,133)(H4,89,90,94)(H4,91,92,95)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m0/s1 DXRJJIPQJUARAV-SZMGYULJSA-N 50270787 CHEMBL509774::NSFCRGRPGHFGGCYLF IgG receptor FcRn large subunit p51 Homo sapiens 93000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270787&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935179 104115849 CHEMBL509774 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415520 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)[C@@H](C)CC InChI=1S/C85H118N20O26S2/c1-8-42(4)68-82(127)98-56(31-48-20-24-51(108)25-21-48)77(122)101-61(80(125)96-54(29-46-15-12-11-13-16-46)75(120)97-58(33-63(86)109)74(119)92-45(7)85(130)131)39-132-133-40-62(102-76(121)55(30-47-18-22-50(107)23-19-47)95-79(124)60(38-106)100-73(118)52-17-14-28-88-52)81(126)105-69(43(5)9-2)83(128)94-53(26-27-66(112)113)71(116)89-36-64(110)93-57(32-49-35-87-41-91-49)78(123)104-70(44(6)10-3)84(129)99-59(34-67(114)115)72(117)90-37-65(111)103-68/h11-13,15-16,18-25,35,41-45,52-62,68-70,88,106-108H,8-10,14,17,26-34,36-40H2,1-7H3,(H2,86,109)(H,87,91)(H,89,116)(H,90,117)(H,92,119)(H,93,110)(H,94,128)(H,95,124)(H,96,125)(H,97,120)(H,98,127)(H,99,129)(H,100,118)(H,101,122)(H,102,121)(H,103,111)(H,104,123)(H,105,126)(H,112,113)(H,114,115)(H,130,131)/t42-,43-,44-,45-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-,69-,70-/m0/s1 IQARFOIQUSLJBV-HFVQQTQISA-N 50270786 CHEMBL501558::PSYCIEGHIDGIYCFNA IgG receptor FcRn large subunit p51 Homo sapiens 76000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270786&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585677 104115848 CHEMBL501558 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415521 CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C80H122N22O21S3/c1-6-44(3)66(101-78(120)67(45(4)7-2)100-68(110)50(83)18-11-13-28-81)77(119)99-59-42-126-125-41-58(74(116)94-51(25-26-61(84)105)69(111)88-38-64(108)92-53(80(122)123)19-12-14-29-82)98-72(114)55(33-47-21-23-49(104)24-22-47)96-71(113)52(27-31-124-5)91-63(107)37-86-62(106)36-87-70(112)54(32-46-16-9-8-10-17-46)95-73(115)56(34-48-35-85-43-90-48)93-65(109)39-89-76(118)60-20-15-30-102(60)79(121)57(40-103)97-75(59)117/h8-10,16-17,21-24,35,43-45,50-60,66-67,103-104H,6-7,11-15,18-20,25-34,36-42,81-83H2,1-5H3,(H2,84,105)(H,85,90)(H,86,106)(H,87,112)(H,88,111)(H,89,118)(H,91,107)(H,92,108)(H,93,109)(H,94,116)(H,95,115)(H,96,113)(H,97,117)(H,98,114)(H,99,119)(H,100,110)(H,101,120)(H,122,123)/t44-,45-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,66-,67-/m0/s1 PTIKFFAQESKEGS-RLYKKVSASA-N 50270785 CHEMBL503219::KIICSPGHFGGMYCQGK IgG receptor FcRn large subunit p51 Homo sapiens 78000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270785&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585676 104115847 CHEMBL503219 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415522 CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@H](C)O InChI=1S/C75H103N21O23S2/c1-6-38(4)63-74(117)92-49(24-42-14-18-45(99)19-15-42)67(110)93-53(70(113)91-51(26-55(78)101)69(112)90-48(23-41-12-16-44(98)17-13-41)66(109)88-46(75(118)119)20-21-54(77)100)35-121-120-34-52(87-59(105)31-81-57(103)29-80-56(102)27-76)71(114)95-62(37(2)3)73(116)96-64(39(5)97)72(115)84-33-60(106)86-50(25-43-28-79-36-85-43)68(111)89-47(22-40-10-8-7-9-11-40)65(108)83-30-58(104)82-32-61(107)94-63/h7-19,28,36-39,46-53,62-64,97-99H,6,20-27,29-35,76H2,1-5H3,(H2,77,100)(H2,78,101)(H,79,85)(H,80,102)(H,81,103)(H,82,104)(H,83,108)(H,84,115)(H,86,106)(H,87,105)(H,88,109)(H,89,111)(H,90,112)(H,91,113)(H,92,117)(H,93,110)(H,94,107)(H,95,114)(H,96,116)(H,118,119)/t38-,39-,46-,47-,48-,49-,50-,51-,52-,53-,62-,63-,64-/m0/s1 RNDLHDADENIYQB-PYKOPHRNSA-N 50270784 CHEMBL499790::GGGCVTGHFGGIYCNYQ IgG receptor FcRn large subunit p51 Homo sapiens 35000 7.4 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270784&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 44585675 104115846 CHEMBL499790 C02716 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415523 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-44(2)31-53(74(120)102-58(34-48-20-22-50(109)23-21-48)81(127)107-30-11-18-61(107)79(125)104-59(41-130)77(123)101-57(36-64(86)111)72(118)94-40-68(115)106-29-12-19-62(106)82(128)129)97-67(114)39-92-66(113)38-93-71(117)54(32-46-13-6-4-7-14-46)99-76(122)56(35-49-37-89-43-95-49)96-65(112)26-28-90-80(126)69(45(3)108)105-78(124)60(42-131)103-75(121)55(33-47-15-8-5-9-16-47)100-73(119)52(17-10-27-91-83(87)88)98-70(116)51(84)24-25-63(85)110/h4-9,13-16,20-23,37,43-45,51-62,69,108-109,130-131H,10-12,17-19,24-36,38-42,84H2,1-3H3,(H2,85,110)(H2,86,111)(H,89,95)(H,90,126)(H,92,113)(H,93,117)(H,94,118)(H,96,112)(H,97,114)(H,98,116)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,91)/t45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,69+/m1/s1 DAHXZURNAMOGSP-NQDMWGEESA-N 50270837 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{3-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]propanamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL508702 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270837&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935218 104115899 CHEMBL508702 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415524 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C84H120N24O22S2/c1-43(2)31-54(75(121)103-59(34-49-22-24-51(110)25-23-49)82(128)108-30-13-20-62(108)80(126)105-60(40-131)78(124)102-58(36-65(87)112)72(118)93-39-67(114)107-29-14-21-63(107)83(129)130)99-70(116)45(4)95-69(115)44(3)96-74(120)55(32-47-15-8-6-9-16-47)101-77(123)57(35-50-37-90-42-94-50)97-66(113)38-92-81(127)68(46(5)109)106-79(125)61(41-132)104-76(122)56(33-48-17-10-7-11-18-48)100-73(119)53(19-12-28-91-84(88)89)98-71(117)52(85)26-27-64(86)111/h6-11,15-18,22-25,37,42-46,52-63,68,109-110,131-132H,12-14,19-21,26-36,38-41,85H2,1-5H3,(H2,86,111)(H2,87,112)(H,90,94)(H,92,127)(H,93,118)(H,95,115)(H,96,120)(H,97,113)(H,98,117)(H,99,116)(H,100,119)(H,101,123)(H,102,124)(H,103,121)(H,104,122)(H,105,126)(H,106,125)(H,129,130)(H4,88,89,91)/t44-,45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,68+/m1/s1 ZBSWPNUTNJHBSC-IILIRIRYSA-N 50270836 CHEMBL499664 IgG receptor FcRn large subunit p51 Homo sapiens 69000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270836&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935217 104115898 CHEMBL499664 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415525 CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)98-69(115)44(3)95-65(112)37-91-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)96-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,117)(H,92,126)(H,93,118)(H,95,112)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 NVLFUIQQQXPSCK-QPXGSZJPSA-N 50270835 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2R)-2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}propanamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL499402 IgG receptor FcRn large subunit p51 Homo sapiens 57000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270835&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935216 104115897 CHEMBL499402 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415526 CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)71(117)93-39-67(114)106-28-13-20-62(106)82(128)129)96-65(112)37-91-69(115)44(3)95-73(119)54(31-46-14-7-5-8-15-46)100-76(122)56(34-49-36-89-42-94-49)97-66(113)38-92-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)99-72(118)52(18-11-27-90-83(87)88)98-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,115)(H,92,126)(H,93,117)(H,95,119)(H,96,112)(H,97,113)(H,98,116)(H,99,118)(H,100,122)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 HROBHVURICMOFT-QPXGSZJPSA-N 50270834 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]acetamido}-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]propanamido]acetamido}-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL506644 IgG receptor FcRn large subunit p51 Homo sapiens 48000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270834&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935215 104115896 CHEMBL506644 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415527 CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C83H118N24O22S2/c1-43(2)30-53(74(120)102-58(33-48-21-23-50(109)24-22-48)81(127)107-29-12-19-61(107)79(125)104-59(40-130)77(123)101-57(35-64(86)111)72(118)93-39-67(114)106-28-13-20-62(106)82(128)129)96-66(113)38-91-65(112)37-92-71(117)54(31-46-14-7-5-8-15-46)99-76(122)56(34-49-36-89-42-94-49)98-69(115)44(3)95-80(126)68(45(4)108)105-78(124)60(41-131)103-75(121)55(32-47-16-9-6-10-17-47)100-73(119)52(18-11-27-90-83(87)88)97-70(116)51(84)25-26-63(85)110/h5-10,14-17,21-24,36,42-45,51-62,68,108-109,130-131H,11-13,18-20,25-35,37-41,84H2,1-4H3,(H2,85,110)(H2,86,111)(H,89,94)(H,91,112)(H,92,117)(H,93,118)(H,95,126)(H,96,113)(H,97,116)(H,98,115)(H,99,122)(H,100,119)(H,101,123)(H,102,120)(H,103,121)(H,104,125)(H,105,124)(H,128,129)(H4,87,88,90)/t44-,45-,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+/m1/s1 BAXZNYMLTXZPTP-QPXGSZJPSA-N 50270833 (2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-[(2R)-2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]propanamido]-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanamido]acetamido}acetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetyl}pyrrolidine-2-carboxylic acid::CHEMBL500533 IgG receptor FcRn large subunit p51 Homo sapiens >125000 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270833&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935214 104115895 CHEMBL500533 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50415528 CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O InChI=1S/C86H124N24O22S2/c1-46(2)33-63(80(127)103-59(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-61(110)79(126)104-60(44-133)78(125)102-58(38-65(89)114)74(121)96-42-68(117)109-31-16-23-62(109)84(131)132)108(7)69(118)43-107(6)67(116)41-95-73(120)55(34-48-17-10-8-11-18-48)100-76(123)57(37-51-39-92-45-97-51)98-66(115)40-94-81(128)70(47(3)111)105-82(129)71(86(4,5)134)106-77(124)56(35-49-19-12-9-13-20-49)101-75(122)54(21-14-30-93-85(90)91)99-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,45-47,53-63,70-71,111-112,133-134H,14-16,21-23,28-38,40-44,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,128)(H,95,120)(H,96,121)(H,98,115)(H,99,119)(H,100,123)(H,101,122)(H,102,125)(H,103,127)(H,104,126)(H,105,129)(H,106,124)(H,131,132)(H4,90,91,93)/t47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+,71-/m1/s1 GKJCQNBXNUROBJ-MOZDKIGJSA-N 50270832 CHEMBL525265 IgG receptor FcRn large subunit p51 Homo sapiens 420 ChEMBL 10.1016/j.bmc.2008.05.004 10.7270/Q2QV3M9C 18501614 Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270832&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 91935213 104115894 CHEMBL525265 C02248 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566560 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)[C@@H](C)O)C2=O InChI=1S/C75H103N19O17S2/c1-41(2)31-57-69(107)86-51(32-46-24-26-48(97)27-25-46)61(100)73(111)94-30-16-23-56(94)68(106)89-55(63(76)101)39-112-113-75(5,6)62(91-67(105)53(34-45-19-12-9-13-20-45)87-64(102)49(83-43(4)96)21-14-28-80-74(77)78)71(109)90-60(42(3)95)70(108)81-37-58(98)84-54(35-47-36-79-40-82-47)66(104)88-52(33-44-17-10-8-11-18-44)65(103)85-50-22-15-29-93(72(50)110)38-59(99)92(57)7/h8-13,17-20,24-27,36,40-42,49-57,60,62,95,97H,14-16,21-23,28-35,37-39H2,1-7H3,(H2,76,101)(H,79,82)(H,81,108)(H,83,96)(H,84,98)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,109)(H,91,105)(H4,77,78,80)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,60+,62-/m1/s1 VQKDVUMXEKQBRJ-BHTBMSJOSA-N 50314078 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-26-[(1R)-1-hydroxyethyl]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22-trimethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089946 IgG receptor FcRn large subunit p51 Homo sapiens 430 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314078&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883955 104148439 CHEMBL1089946 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566561 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)[C@@H](C)O)C2=O InChI=1S/C75H103N19O17S2/c1-41(2)31-57-69(107)86-51(32-46-24-26-48(97)27-25-46)61(100)73(111)94-30-16-23-56(94)68(106)89-55(63(76)101)39-112-113-75(5,6)62(91-67(105)53(34-45-19-12-9-13-20-45)87-64(102)49(83-43(4)96)21-14-28-80-74(77)78)71(109)90-60(42(3)95)70(108)81-37-58(98)84-54(35-47-36-79-40-82-47)66(104)88-52(33-44-17-10-8-11-18-44)65(103)85-50-22-15-29-93(72(50)110)38-59(99)92(57)7/h8-13,17-20,24-27,36,40-42,49-57,60,62,95,97H,14-16,21-23,28-35,37-39H2,1-7H3,(H2,76,101)(H,79,82)(H,81,108)(H,83,96)(H,84,98)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,109)(H,91,105)(H4,77,78,80)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,60+,62-/m1/s1 VQKDVUMXEKQBRJ-BHTBMSJOSA-N 50314078 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-26-[(1R)-1-hydroxyethyl]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22-trimethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089946 IgG receptor FcRn large subunit p51 Homo sapiens 43 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314078&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883955 104148439 CHEMBL1089946 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566562 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)[C@@H](C)O)C2=O InChI=1S/C75H103N19O17S2/c1-41(2)31-57-69(107)86-51(32-46-24-26-48(97)27-25-46)61(100)73(111)94-30-16-23-56(94)68(106)89-55(63(76)101)39-112-113-75(5,6)62(91-67(105)53(34-45-19-12-9-13-20-45)87-64(102)49(83-43(4)96)21-14-28-80-74(77)78)71(109)90-60(42(3)95)70(108)81-37-58(98)84-54(35-47-36-79-40-82-47)66(104)88-52(33-44-17-10-8-11-18-44)65(103)85-50-22-15-29-93(72(50)110)38-59(99)92(57)7/h8-13,17-20,24-27,36,40-42,49-57,60,62,95,97H,14-16,21-23,28-35,37-39H2,1-7H3,(H2,76,101)(H,79,82)(H,81,108)(H,83,96)(H,84,98)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,109)(H,91,105)(H4,77,78,80)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,60+,62-/m1/s1 VQKDVUMXEKQBRJ-BHTBMSJOSA-N 50314078 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-26-[(1R)-1-hydroxyethyl]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22-trimethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089946 IgG receptor FcRn large subunit p51 Homo sapiens 260 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314078&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883955 104148439 CHEMBL1089946 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566563 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O InChI=1S/C75H103N19O16S2/c1-42(2)32-58-70(107)86-52(33-47-25-27-49(96)28-26-47)61(99)72(109)94-31-17-24-57(94)69(106)89-56(63(76)100)40-111-112-75(5,6)62(90-68(105)54(35-46-20-13-10-14-21-46)87-65(102)50(83-44(4)95)22-15-29-80-74(77)78)73(110)91(7)43(3)64(101)81-38-59(97)84-55(36-48-37-79-41-82-48)67(104)88-53(34-45-18-11-9-12-19-45)66(103)85-51-23-16-30-93(71(51)108)39-60(98)92(58)8/h9-14,18-21,25-28,37,41-43,50-58,62,96H,15-17,22-24,29-36,38-40H2,1-8H3,(H2,76,100)(H,79,82)(H,81,101)(H,83,95)(H,84,97)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,105)(H4,77,78,80)/t43-,50-,51-,52-,53-,54-,55-,56-,57-,58-,62+/m0/s1 WGYWJJXNJFPTML-JHZPGZIOSA-N 50314079 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22,25,26-pentamethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089947 IgG receptor FcRn large subunit p51 Homo sapiens 1100 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314079&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883956 104148440 CHEMBL1089947 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566564 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O InChI=1S/C75H103N19O16S2/c1-42(2)32-58-70(107)86-52(33-47-25-27-49(96)28-26-47)61(99)72(109)94-31-17-24-57(94)69(106)89-56(63(76)100)40-111-112-75(5,6)62(90-68(105)54(35-46-20-13-10-14-21-46)87-65(102)50(83-44(4)95)22-15-29-80-74(77)78)73(110)91(7)43(3)64(101)81-38-59(97)84-55(36-48-37-79-41-82-48)67(104)88-53(34-45-18-11-9-12-19-45)66(103)85-51-23-16-30-93(71(51)108)39-60(98)92(58)8/h9-14,18-21,25-28,37,41-43,50-58,62,96H,15-17,22-24,29-36,38-40H2,1-8H3,(H2,76,100)(H,79,82)(H,81,101)(H,83,95)(H,84,97)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,105)(H4,77,78,80)/t43-,50-,51-,52-,53-,54-,55-,56-,57-,58-,62+/m0/s1 WGYWJJXNJFPTML-JHZPGZIOSA-N 50314079 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22,25,26-pentamethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089947 IgG receptor FcRn large subunit p51 Homo sapiens 150 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314079&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883956 104148440 CHEMBL1089947 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566565 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O InChI=1S/C75H103N19O16S2/c1-42(2)32-58-70(107)86-52(33-47-25-27-49(96)28-26-47)61(99)72(109)94-31-17-24-57(94)69(106)89-56(63(76)100)40-111-112-75(5,6)62(90-68(105)54(35-46-20-13-10-14-21-46)87-65(102)50(83-44(4)95)22-15-29-80-74(77)78)73(110)91(7)43(3)64(101)81-38-59(97)84-55(36-48-37-79-41-82-48)67(104)88-53(34-45-18-11-9-12-19-45)66(103)85-51-23-16-30-93(71(51)108)39-60(98)92(58)8/h9-14,18-21,25-28,37,41-43,50-58,62,96H,15-17,22-24,29-36,38-40H2,1-8H3,(H2,76,100)(H,79,82)(H,81,101)(H,83,95)(H,84,97)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,105)(H4,77,78,80)/t43-,50-,51-,52-,53-,54-,55-,56-,57-,58-,62+/m0/s1 WGYWJJXNJFPTML-JHZPGZIOSA-N 50314079 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22,25,26-pentamethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089947 IgG receptor FcRn large subunit p51 Homo sapiens 950 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314079&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883956 104148440 CHEMBL1089947 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566566 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C73H101N19O17S2/c1-40(2)29-55-68(106)84-49(30-45-23-25-47(95)26-24-45)60(99)71(109)92-28-16-22-54(92)67(105)87-53(62(74)100)38-110-111-73(5,6)61(89-66(104)51(32-44-19-13-10-14-20-44)86-64(102)48(82-42(4)94)21-15-27-78-72(75)76)70(108)88-59(41(3)93)69(107)79-35-56(96)83-52(33-46-34-77-39-81-46)65(103)85-50(31-43-17-11-9-12-18-43)63(101)80-36-57(97)90(7)37-58(98)91(55)8/h9-14,17-20,23-26,34,39-41,48-55,59,61,93,95H,15-16,21-22,27-33,35-38H2,1-8H3,(H2,74,100)(H,77,81)(H,79,107)(H,80,101)(H,82,94)(H,83,96)(H,84,106)(H,85,103)(H,86,102)(H,87,105)(H,88,108)(H,89,104)(H4,75,76,78)/t41-,48+,49+,50+,51+,52+,53+,54+,55+,59+,61-/m1/s1 XVQSPNCSNCKCMI-PCQLJHSASA-N 50314080 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089948 IgG receptor FcRn large subunit p51 Homo sapiens 520 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314080&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883957 104148441 CHEMBL1089948 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566567 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C73H101N19O17S2/c1-40(2)29-55-68(106)84-49(30-45-23-25-47(95)26-24-45)60(99)71(109)92-28-16-22-54(92)67(105)87-53(62(74)100)38-110-111-73(5,6)61(89-66(104)51(32-44-19-13-10-14-20-44)86-64(102)48(82-42(4)94)21-15-27-78-72(75)76)70(108)88-59(41(3)93)69(107)79-35-56(96)83-52(33-46-34-77-39-81-46)65(103)85-50(31-43-17-11-9-12-18-43)63(101)80-36-57(97)90(7)37-58(98)91(55)8/h9-14,17-20,23-26,34,39-41,48-55,59,61,93,95H,15-16,21-22,27-33,35-38H2,1-8H3,(H2,74,100)(H,77,81)(H,79,107)(H,80,101)(H,82,94)(H,83,96)(H,84,106)(H,85,103)(H,86,102)(H,87,105)(H,88,108)(H,89,104)(H4,75,76,78)/t41-,48+,49+,50+,51+,52+,53+,54+,55+,59+,61-/m1/s1 XVQSPNCSNCKCMI-PCQLJHSASA-N 50314080 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089948 IgG receptor FcRn large subunit p51 Homo sapiens 31 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314080&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883957 104148441 CHEMBL1089948 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566568 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C73H101N19O17S2/c1-40(2)29-55-68(106)84-49(30-45-23-25-47(95)26-24-45)60(99)71(109)92-28-16-22-54(92)67(105)87-53(62(74)100)38-110-111-73(5,6)61(89-66(104)51(32-44-19-13-10-14-20-44)86-64(102)48(82-42(4)94)21-15-27-78-72(75)76)70(108)88-59(41(3)93)69(107)79-35-56(96)83-52(33-46-34-77-39-81-46)65(103)85-50(31-43-17-11-9-12-18-43)63(101)80-36-57(97)90(7)37-58(98)91(55)8/h9-14,17-20,23-26,34,39-41,48-55,59,61,93,95H,15-16,21-22,27-33,35-38H2,1-8H3,(H2,74,100)(H,77,81)(H,79,107)(H,80,101)(H,82,94)(H,83,96)(H,84,106)(H,85,103)(H,86,102)(H,87,105)(H,88,108)(H,89,104)(H4,75,76,78)/t41-,48+,49+,50+,51+,52+,53+,54+,55+,59+,61-/m1/s1 XVQSPNCSNCKCMI-PCQLJHSASA-N 50314080 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089948 IgG receptor FcRn large subunit p51 Homo sapiens 170 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314080&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883957 104148441 CHEMBL1089948 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566569 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccc(cc2)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C68H97N19O16S2/c1-36(2)28-50-62(100)80-45(29-41-20-24-43(90)25-21-41)55(94)65(103)87-27-13-17-49(87)61(99)82-48(57(69)95)35-104-105-68(5,6)56(84-60(98)47(30-39-14-10-9-11-15-39)81-59(97)44(77-38(4)89)16-12-26-74-66(70)71)64(102)83-54(37(3)88)63(101)75-32-51(91)79-46(31-40-18-22-42(23-19-40)78-67(72)73)58(96)76-33-52(92)85(7)34-53(93)86(50)8/h9-11,14-15,18-25,36-37,44-50,54,56,88,90H,12-13,16-17,26-35H2,1-8H3,(H2,69,95)(H,75,101)(H,76,96)(H,77,89)(H,79,91)(H,80,100)(H,81,97)(H,82,99)(H,83,102)(H,84,98)(H4,70,71,74)(H4,72,73,78)/t37-,44+,45+,46+,47+,48+,49+,50+,54+,56-/m1/s1 DFZNYFWFCYPCIR-RTUTXIKTSA-N 50314081 (3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-17-(4-guanidinobenzyl)-29-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-26-isobutyl-7,7,22,25-tetramethyl-1,9,12,15,18,21,24,27,30,31-decaoxodotriacontahydro-1H-pyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30]dithianonaazacyclotritriacontine-3-carboxamide::CHEMBL1089949 IgG receptor FcRn large subunit p51 Homo sapiens 1000 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314081&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883958 104148442 CHEMBL1089949 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566570 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccc(cc2)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C68H97N19O16S2/c1-36(2)28-50-62(100)80-45(29-41-20-24-43(90)25-21-41)55(94)65(103)87-27-13-17-49(87)61(99)82-48(57(69)95)35-104-105-68(5,6)56(84-60(98)47(30-39-14-10-9-11-15-39)81-59(97)44(77-38(4)89)16-12-26-74-66(70)71)64(102)83-54(37(3)88)63(101)75-32-51(91)79-46(31-40-18-22-42(23-19-40)78-67(72)73)58(96)76-33-52(92)85(7)34-53(93)86(50)8/h9-11,14-15,18-25,36-37,44-50,54,56,88,90H,12-13,16-17,26-35H2,1-8H3,(H2,69,95)(H,75,101)(H,76,96)(H,77,89)(H,79,91)(H,80,100)(H,81,97)(H,82,99)(H,83,102)(H,84,98)(H4,70,71,74)(H4,72,73,78)/t37-,44+,45+,46+,47+,48+,49+,50+,54+,56-/m1/s1 DFZNYFWFCYPCIR-RTUTXIKTSA-N 50314081 (3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-17-(4-guanidinobenzyl)-29-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-26-isobutyl-7,7,22,25-tetramethyl-1,9,12,15,18,21,24,27,30,31-decaoxodotriacontahydro-1H-pyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30]dithianonaazacyclotritriacontine-3-carboxamide::CHEMBL1089949 IgG receptor FcRn large subunit p51 Homo sapiens 62 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314081&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883958 104148442 CHEMBL1089949 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566571 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccc(cc2)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C68H97N19O16S2/c1-36(2)28-50-62(100)80-45(29-41-20-24-43(90)25-21-41)55(94)65(103)87-27-13-17-49(87)61(99)82-48(57(69)95)35-104-105-68(5,6)56(84-60(98)47(30-39-14-10-9-11-15-39)81-59(97)44(77-38(4)89)16-12-26-74-66(70)71)64(102)83-54(37(3)88)63(101)75-32-51(91)79-46(31-40-18-22-42(23-19-40)78-67(72)73)58(96)76-33-52(92)85(7)34-53(93)86(50)8/h9-11,14-15,18-25,36-37,44-50,54,56,88,90H,12-13,16-17,26-35H2,1-8H3,(H2,69,95)(H,75,101)(H,76,96)(H,77,89)(H,79,91)(H,80,100)(H,81,97)(H,82,99)(H,83,102)(H,84,98)(H4,70,71,74)(H4,72,73,78)/t37-,44+,45+,46+,47+,48+,49+,50+,54+,56-/m1/s1 DFZNYFWFCYPCIR-RTUTXIKTSA-N 50314081 (3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-17-(4-guanidinobenzyl)-29-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-26-isobutyl-7,7,22,25-tetramethyl-1,9,12,15,18,21,24,27,30,31-decaoxodotriacontahydro-1H-pyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30]dithianonaazacyclotritriacontine-3-carboxamide::CHEMBL1089949 IgG receptor FcRn large subunit p51 Homo sapiens 74 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314081&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883958 104148442 CHEMBL1089949 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566572 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1 GRNGOJKQKRCTFF-BGGXCMKMSA-N 50314082 CHEMBL1089950 IgG receptor FcRn large subunit p51 Homo sapiens 22000 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314082&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883959 104148443 CHEMBL1089950 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566573 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1 GRNGOJKQKRCTFF-BGGXCMKMSA-N 50314082 CHEMBL1089950 IgG receptor FcRn large subunit p51 Homo sapiens 2600 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314082&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883959 104148443 CHEMBL1089950 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566574 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1 GRNGOJKQKRCTFF-BGGXCMKMSA-N 50314082 CHEMBL1089950 IgG receptor FcRn large subunit p51 Homo sapiens 18000 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314082&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883959 104148443 CHEMBL1089950 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566578 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CSCCC(=O)NCCCN(CCCNC(=O)CCSCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)CC(=O)NCC(O)=O)[C@@H](C)O InChI=1S/C187H262N50O50S2/c1-104(2)74-138-181(282)218-122(76-112-49-53-116(240)54-50-112)161(262)185(286)236-70-30-47-136(236)179(280)216-118(169(270)223-130(84-141(189)243)167(268)207-94-154(256)234-68-28-45-134(234)163(191)264)42-23-25-61-199-145(247)86-132(177(278)227-159(106(5)238)183(284)203-90-147(249)212-128(82-114-88-195-102-209-114)175(276)220-124(78-108-34-15-11-16-35-108)165(266)205-92-152(254)229(7)98-156(258)231(138)9)225-173(274)126(80-110-38-19-13-20-39-110)214-151(253)101-289-73-60-144(246)198-65-33-67-233(97-149(251)202-96-158(260)261)66-32-64-197-143(245)59-72-288-100-150(252)211-121(57-58-140(188)242)172(273)215-120(44-27-63-201-187(193)194)171(272)222-127(81-111-40-21-14-22-41-111)174(275)226-133-87-146(248)200-62-26-24-43-119(170(271)224-131(85-142(190)244)168(269)208-95-155(257)235-69-29-46-135(235)164(192)265)217-180(281)137-48-31-71-237(137)186(287)162(263)123(77-113-51-55-117(241)56-52-113)219-182(283)139(75-105(3)4)232(10)157(259)99-230(8)153(255)93-206-166(267)125(79-109-36-17-12-18-37-109)221-176(277)129(83-115-89-196-103-210-115)213-148(250)91-204-184(285)160(107(6)239)228-178(133)279/h11-22,34-41,49-56,88-89,102-107,118-139,159-160,238-241H,23-33,42-48,57-87,90-101H2,1-10H3,(H2,188,242)(H2,189,243)(H2,190,244)(H2,191,264)(H2,192,265)(H,195,209)(H,196,210)(H,197,245)(H,198,246)(H,199,247)(H,200,248)(H,202,251)(H,203,284)(H,204,285)(H,205,266)(H,206,267)(H,207,268)(H,208,269)(H,211,252)(H,212,249)(H,213,250)(H,214,253)(H,215,273)(H,216,280)(H,217,281)(H,218,282)(H,219,283)(H,220,276)(H,221,277)(H,222,272)(H,223,270)(H,224,271)(H,225,274)(H,226,275)(H,227,278)(H,228,279)(H,260,261)(H4,193,194,201)/t106-,107-,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,131+,132+,133+,134+,135+,136+,137+,138+,139+,159+,160+/m1/s1 KDMOSSJUYPQAQO-WXMHCLMHSA-N 50314084 CHEMBL1089952 IgG receptor FcRn large subunit p51 Homo sapiens 600 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314084&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883961 104148445 CHEMBL1089952 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566579 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CSCCC(=O)NCCC(=O)NCCCN(C)CCCNC(=O)CCNC(=O)CCSCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)[C@@H](C)O InChI=1S/C190H269N51O49S2/c1-107(2)79-141-184(285)222-125(81-115-50-54-119(244)55-51-115)164(265)188(289)240-75-31-48-139(240)182(283)220-121(172(273)227-133(89-144(192)247)170(271)211-99-158(261)238-73-29-46-137(238)166(194)267)43-24-26-64-202-150(253)91-135(180(281)231-162(109(5)242)186(287)207-95-152(255)216-131(87-117-93-198-105-213-117)178(279)224-127(83-111-35-16-12-17-36-111)168(269)209-97-156(259)234(8)101-160(263)236(141)10)229-176(277)129(85-113-39-20-14-21-40-113)218-155(258)104-292-78-63-149(252)205-70-61-147(250)201-68-34-72-233(7)71-33-67-200-146(249)60-69-204-148(251)62-77-291-103-154(257)215-124(58-59-143(191)246)175(276)219-123(45-28-66-206-190(196)197)174(275)226-130(86-114-41-22-15-23-42-114)177(278)230-136-92-151(254)203-65-27-25-44-122(173(274)228-134(90-145(193)248)171(272)212-100-159(262)239-74-30-47-138(239)167(195)268)221-183(284)140-49-32-76-241(140)189(290)165(266)126(82-116-52-56-120(245)57-53-116)223-185(286)142(80-108(3)4)237(11)161(264)102-235(9)157(260)98-210-169(270)128(84-112-37-18-13-19-38-112)225-179(280)132(88-118-94-199-106-214-118)217-153(256)96-208-187(288)163(110(6)243)232-181(136)282/h12-23,35-42,50-57,93-94,105-110,121-142,162-163,242-245H,24-34,43-49,58-92,95-104H2,1-11H3,(H2,191,246)(H2,192,247)(H2,193,248)(H2,194,267)(H2,195,268)(H,198,213)(H,199,214)(H,200,249)(H,201,250)(H,202,253)(H,203,254)(H,204,251)(H,205,252)(H,207,287)(H,208,288)(H,209,269)(H,210,270)(H,211,271)(H,212,272)(H,215,257)(H,216,255)(H,217,256)(H,218,258)(H,219,276)(H,220,283)(H,221,284)(H,222,285)(H,223,286)(H,224,279)(H,225,280)(H,226,275)(H,227,273)(H,228,274)(H,229,277)(H,230,278)(H,231,281)(H,232,282)(H4,196,197,206)/t109-,110-,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,131+,132+,133+,134+,135+,136+,137+,138+,139+,140+,141+,142+,162+,163+/m1/s1 HTNXRINFIAYTFL-LNCVCUNLSA-N 50314085 CHEMBL1090273 IgG receptor FcRn large subunit p51 Homo sapiens 2400 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314085&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883962 104148446 CHEMBL1090273 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566580 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CSCCC(=O)NCCC(=O)NCCC(=O)NCCCN(CCCNC(=O)CCNC(=O)CCSCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)CC(=O)NCC(O)=O)[C@@H](C)O InChI=1S/C196H277N53O53S2/c1-110(2)80-144-190(297)230-128(82-118-49-53-122(252)54-50-118)170(277)194(301)248-76-30-47-142(248)188(295)228-124(178(285)235-136(90-147(198)255)176(283)219-100-163(271)246-74-28-45-140(246)172(200)279)42-23-25-64-208-154(262)92-138(186(293)239-168(112(5)250)192(299)215-96-156(264)224-134(88-120-94-204-108-221-120)184(291)232-130(84-114-34-15-11-16-35-114)174(281)217-98-161(269)241(7)104-165(273)243(144)9)237-182(289)132(86-116-38-19-13-20-39-116)226-160(268)107-304-79-63-153(261)212-71-61-151(259)210-69-59-149(257)206-67-32-72-245(103-158(266)214-102-167(275)276)73-33-68-207-150(258)60-70-211-152(260)62-78-303-106-159(267)223-127(57-58-146(197)254)181(288)227-126(44-27-66-213-196(202)203)180(287)234-133(87-117-40-21-14-22-41-117)183(290)238-139-93-155(263)209-65-26-24-43-125(179(286)236-137(91-148(199)256)177(284)220-101-164(272)247-75-29-46-141(247)173(201)280)229-189(296)143-48-31-77-249(143)195(302)171(278)129(83-119-51-55-123(253)56-52-119)231-191(298)145(81-111(3)4)244(10)166(274)105-242(8)162(270)99-218-175(282)131(85-115-36-17-12-18-37-115)233-185(292)135(89-121-95-205-109-222-121)225-157(265)97-216-193(300)169(113(6)251)240-187(139)294/h11-22,34-41,49-56,94-95,108-113,124-145,168-169,250-253H,23-33,42-48,57-93,96-107H2,1-10H3,(H2,197,254)(H2,198,255)(H2,199,256)(H2,200,279)(H2,201,280)(H,204,221)(H,205,222)(H,206,257)(H,207,258)(H,208,262)(H,209,263)(H,210,259)(H,211,260)(H,212,261)(H,214,266)(H,215,299)(H,216,300)(H,217,281)(H,218,282)(H,219,283)(H,220,284)(H,223,267)(H,224,264)(H,225,265)(H,226,268)(H,227,288)(H,228,295)(H,229,296)(H,230,297)(H,231,298)(H,232,291)(H,233,292)(H,234,287)(H,235,285)(H,236,286)(H,237,289)(H,238,290)(H,239,293)(H,240,294)(H,275,276)(H4,202,203,213)/t112-,113-,124+,125+,126+,127+,128+,129+,130+,131+,132+,133+,134+,135+,136+,137+,138+,139+,140+,141+,142+,143+,144+,145+,168+,169+/m1/s1 BBJSUWWFBXTQQF-MGSQAVGYSA-N 50314086 CHEMBL1090274 IgG receptor FcRn large subunit p51 Homo sapiens 1100 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314086&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883963 104148447 CHEMBL1090274 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566581 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CSCCC(=O)NCCC(=O)NCCC(=O)NCCNCCCN(CCCNC(=O)CCNC(=O)CCNC(=O)CCNC(=O)CCSC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)CC(=O)NCC(O)=O)[C@@H](C)O InChI=1S/C203H290N56O55S2/c1-115(2)86-149-196(308)239-133(88-123-49-53-127(262)54-50-123)176(288)200(312)258-82-30-47-147(258)194(306)237-129(184(296)244-141(96-152(205)265)182(294)229-106-169(282)256-80-28-45-145(256)178(207)290)42-23-25-67-215-161(274)98-143(192(304)249-174(117(5)260)198(310)225-102-163(276)233-139(94-125-100-212-113-231-125)190(302)241-135(90-119-34-15-11-16-35-119)180(292)227-104-167(280)251(7)110-171(284)253(149)9)246-188(300)137(92-121-38-19-13-20-39-121)235-166(279)112-315-84-64-159(272)220-74-61-156(269)219-73-63-158(271)222-77-76-211-66-32-78-255(109-165(278)224-108-173(286)287)79-33-70-214-154(267)59-71-217-155(268)60-72-218-157(270)62-75-221-160(273)65-85-316-203(314)248-132(57-58-151(204)264)187(299)236-131(44-27-69-223-202(209)210)186(298)243-138(93-122-40-21-14-22-41-122)189(301)247-144-99-162(275)216-68-26-24-43-130(185(297)245-142(97-153(206)266)183(295)230-107-170(283)257-81-29-46-146(257)179(208)291)238-195(307)148-48-31-83-259(148)201(313)177(289)134(89-124-51-55-128(263)56-52-124)240-197(309)150(87-116(3)4)254(10)172(285)111-252(8)168(281)105-228-181(293)136(91-120-36-17-12-18-37-120)242-191(303)140(95-126-101-213-114-232-126)234-164(277)103-226-199(311)175(118(6)261)250-193(144)305/h11-22,34-41,49-56,100-101,113-118,129-150,174-175,211,260-263H,23-33,42-48,57-99,102-112H2,1-10H3,(H2,204,264)(H2,205,265)(H2,206,266)(H2,207,290)(H2,208,291)(H,212,231)(H,213,232)(H,214,267)(H,215,274)(H,216,275)(H,217,268)(H,218,270)(H,219,269)(H,220,272)(H,221,273)(H,222,271)(H,224,278)(H,225,310)(H,226,311)(H,227,292)(H,228,293)(H,229,294)(H,230,295)(H,233,276)(H,234,277)(H,235,279)(H,236,299)(H,237,306)(H,238,307)(H,239,308)(H,240,309)(H,241,302)(H,242,303)(H,243,298)(H,244,296)(H,245,297)(H,246,300)(H,247,301)(H,248,314)(H,249,304)(H,250,305)(H,286,287)(H4,209,210,223)/t117-,118-,129+,130+,131+,132+,133+,134+,135+,136+,137+,138+,139+,140+,141+,142+,143+,144+,145+,146+,147+,148+,149+,150+,174+,175+/m1/s1 YAVIMENCSPKIEW-CEQWYFBNSA-N 50314087 CHEMBL1090275 IgG receptor FcRn large subunit p51 Homo sapiens 710 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314087&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883964 104148448 CHEMBL1090275 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566582 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CSCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)[C@@H](C)O InChI=1S/C171H234N46O45S/c1-92(2)64-126-165(257)199-110(66-100-47-51-104(220)52-48-100)145(237)169(261)216-62-30-45-124(216)163(255)197-106(153(245)204-118(74-129(173)223)151(243)188-84-139(233)214-60-28-43-122(214)147(175)239)40-23-25-57-181-131(225)76-120(161(253)208-143(94(5)218)167(259)184-80-133(227)193-116(72-102-78-179-90-190-102)159(251)201-112(68-96-32-15-11-16-33-96)149(241)186-82-137(231)210(7)86-141(235)212(126)9)206-157(249)114(70-98-36-19-13-20-37-98)195-136(230)89-263-88-135(229)192-109(55-56-128(172)222)156(248)196-108(42-27-59-183-171(177)178)155(247)203-115(71-99-38-21-14-22-39-99)158(250)207-121-77-132(226)182-58-26-24-41-107(154(246)205-119(75-130(174)224)152(244)189-85-140(234)215-61-29-44-123(215)148(176)240)198-164(256)125-46-31-63-217(125)170(262)146(238)111(67-101-49-53-105(221)54-50-101)200-166(258)127(65-93(3)4)213(10)142(236)87-211(8)138(232)83-187-150(242)113(69-97-34-17-12-18-35-97)202-160(252)117(73-103-79-180-91-191-103)194-134(228)81-185-168(260)144(95(6)219)209-162(121)254/h11-22,32-39,47-54,78-79,90-95,106-127,143-144,218-221H,23-31,40-46,55-77,80-89H2,1-10H3,(H2,172,222)(H2,173,223)(H2,174,224)(H2,175,239)(H2,176,240)(H,179,190)(H,180,191)(H,181,225)(H,182,226)(H,184,259)(H,185,260)(H,186,241)(H,187,242)(H,188,243)(H,189,244)(H,192,229)(H,193,227)(H,194,228)(H,195,230)(H,196,248)(H,197,255)(H,198,256)(H,199,257)(H,200,258)(H,201,251)(H,202,252)(H,203,247)(H,204,245)(H,205,246)(H,206,249)(H,207,250)(H,208,253)(H,209,254)(H4,177,178,183)/t94-,95-,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,143+,144+/m1/s1 AWJZCTWSNSTNSL-XEHZEODUSA-N 50314088 CHEMBL1090276 IgG receptor FcRn large subunit p51 Homo sapiens 580 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314088&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883965 104148449 CHEMBL1090276 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566583 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(N)=O)[C@@H](C)O InChI=1S/C143H194N40O35S4/c1-77(2)52-95-128(205)169-93(54-85-36-40-89(186)41-37-85)120(197)140(217)182-49-22-34-107(182)136(213)175-103(122(144)199)71-219-221-73-105(134(211)179-118(79(5)184)138(215)159-68-115(194)167-101(60-87-62-150-75-161-87)132(209)171-97(56-81-24-12-8-13-25-81)124(201)157-64-111(190)155-66-113(192)165-95)177-130(207)99(58-83-28-16-10-17-29-83)173-126(203)91(32-20-46-153-142(146)147)163-110(189)45-44-109(188)152-48-51-181(7)70-117(196)164-92(33-21-47-154-143(148)149)127(204)174-100(59-84-30-18-11-19-31-84)131(208)178-106-74-222-220-72-104(123(145)200)176-137(214)108-35-23-50-183(108)141(218)121(198)94(55-86-38-42-90(187)43-39-86)170-129(206)96(53-78(3)4)166-114(193)67-156-112(191)65-158-125(202)98(57-82-26-14-9-15-27-82)172-133(210)102(61-88-63-151-76-162-88)168-116(195)69-160-139(216)119(80(6)185)180-135(106)212/h8-19,24-31,36-43,62-63,75-80,91-108,118-119,184-187H,20-23,32-35,44-61,64-74H2,1-7H3,(H2,144,199)(H2,145,200)(H,150,161)(H,151,162)(H,152,188)(H,155,190)(H,156,191)(H,157,201)(H,158,202)(H,159,215)(H,160,216)(H,163,189)(H,164,196)(H,165,192)(H,166,193)(H,167,194)(H,168,195)(H,169,205)(H,170,206)(H,171,209)(H,172,210)(H,173,203)(H,174,204)(H,175,213)(H,176,214)(H,177,207)(H,178,208)(H,179,211)(H,180,212)(H4,146,147,153)(H4,148,149,154)/t79-,80-,91+,92+,93+,94+,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,118+,119+/m1/s1 OQGNHKRLHPPYED-CCMNPPPMSA-N 50314089 CHEMBL1090277 IgG receptor FcRn large subunit p51 Homo sapiens 3000 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314089&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883966 104148450 CHEMBL1090277 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566584 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H]3C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc4cnc[nH]4)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@H]4CCCN(CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc5ccc(O)cc5)C(=O)C(=O)N5CCC[C@H]5C(=O)N[C@@H](CSSC3(C)C)C(N)=O)C4=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)[C@@H](C)O)C2=O InChI=1S/C155H214N40O35S4/c1-85(2)64-115-142(221)177-103(66-93-46-50-97(198)51-47-93)126(207)150(229)194-61-30-44-113(194)140(219)183-111(130(156)209)81-231-233-154(7,8)128(146(225)185-124(87(5)196)144(223)167-76-119(202)173-109(72-95-74-162-83-169-95)136(215)181-105(68-89-32-18-14-19-33-89)134(213)175-101-42-28-59-192(148(101)227)79-122(205)190(115)12)187-138(217)107(70-91-36-22-16-23-37-91)179-132(211)99(40-26-56-165-152(158)159)171-118(201)55-54-117(200)164-58-63-189(11)78-121(204)172-100(41-27-57-166-153(160)161)133(212)180-108(71-92-38-24-17-25-39-92)139(218)188-129-147(226)186-125(88(6)197)145(224)168-77-120(203)174-110(73-96-75-163-84-170-96)137(216)182-106(69-90-34-20-15-21-35-90)135(214)176-102-43-29-60-193(149(102)228)80-123(206)191(13)116(65-86(3)4)143(222)178-104(67-94-48-52-98(199)53-49-94)127(208)151(230)195-62-31-45-114(195)141(220)184-112(131(157)210)82-232-234-155(129,9)10/h14-25,32-39,46-53,74-75,83-88,99-116,124-125,128-129,196-199H,26-31,40-45,54-73,76-82H2,1-13H3,(H2,156,209)(H2,157,210)(H,162,169)(H,163,170)(H,164,200)(H,167,223)(H,168,224)(H,171,201)(H,172,204)(H,173,202)(H,174,203)(H,175,213)(H,176,214)(H,177,221)(H,178,222)(H,179,211)(H,180,212)(H,181,215)(H,182,216)(H,183,219)(H,184,220)(H,185,225)(H,186,226)(H,187,217)(H,188,218)(H4,158,159,165)(H4,160,161,166)/t87-,88-,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,124+,125+,128-,129-/m1/s1 JEIMZUGCWUMMDE-IOHXCNKMSA-N 50314090 CHEMBL1090278::N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-18-carbamoyl-26-[(1R)-1-hydroxyethyl]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22-trimethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontan-23-yl]carbamoyl}-2-phenylethyl]carbamoyl}-4-carbamimidamidobutyl]-N'-{2-[({[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-18-carbamoyl-26-[(1R)-1-hydroxyeth IgG receptor FcRn large subunit p51 Homo sapiens 3.9 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314090&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883967 104148451 CHEMBL1090278 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566585 CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H]3C(=O)N(C)[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc4cnc[nH]4)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@H]4CCCN(CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc5ccc(O)cc5)C(=O)C(=O)N5CCC[C@H]5C(=O)N[C@@H](CSSC3(C)C)C(N)=O)C4=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O InChI=1S/C155H214N40O33S4/c1-87(2)66-117-144(221)177-105(68-95-48-52-99(196)53-49-95)126(205)148(225)194-63-32-46-115(194)142(219)183-113(130(156)207)83-229-231-154(7,8)128(150(227)188(12)89(5)132(209)167-78-121(200)173-111(74-97-76-162-85-169-97)138(215)181-107(70-91-34-20-16-21-35-91)136(213)175-103-44-30-61-192(146(103)223)81-124(203)190(117)14)185-140(217)109(72-93-38-24-18-25-39-93)179-134(211)101(42-28-58-165-152(158)159)171-120(199)57-56-119(198)164-60-65-187(11)80-123(202)172-102(43-29-59-166-153(160)161)135(212)180-110(73-94-40-26-19-27-41-94)141(218)186-129-151(228)189(13)90(6)133(210)168-79-122(201)174-112(75-98-77-163-86-170-98)139(216)182-108(71-92-36-22-17-23-37-92)137(214)176-104-45-31-62-193(147(104)224)82-125(204)191(15)118(67-88(3)4)145(222)178-106(69-96-50-54-100(197)55-51-96)127(206)149(226)195-64-33-47-116(195)143(220)184-114(131(157)208)84-230-232-155(129,9)10/h16-27,34-41,48-55,76-77,85-90,101-118,128-129,196-197H,28-33,42-47,56-75,78-84H2,1-15H3,(H2,156,207)(H2,157,208)(H,162,169)(H,163,170)(H,164,198)(H,167,209)(H,168,210)(H,171,199)(H,172,202)(H,173,200)(H,174,201)(H,175,213)(H,176,214)(H,177,221)(H,178,222)(H,179,211)(H,180,212)(H,181,215)(H,182,216)(H,183,219)(H,184,220)(H,185,217)(H,186,218)(H4,158,159,165)(H4,160,161,166)/t89-,90-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,128+,129+/m0/s1 BFRWCVKBSPHHQE-QZVFHPQMSA-N 50314091 CHEMBL1090279::N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-18-carbamoyl-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22,25,26-pentamethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontan-23-yl]carbamoyl}-2-phenylethyl]carbamoyl}-4-carbamimidamidobutyl]-N'-{2-[({[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-18-carbamoyl-8-[(4-hydroxyphenyl)methyl]-32-(1H-imi IgG receptor FcRn large subunit p51 Homo sapiens 18 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314091&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883968 104148452 CHEMBL1090279 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566586 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)NCCN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(N)=O)[C@@H](C)O InChI=1S/C155H216N42O37/c1-87(2)64-117-148(229)181-105(66-95-46-50-99(200)51-47-95)132(213)152(233)196-61-30-44-115(196)146(227)179-101(134(156)215)40-24-26-56-164-121(204)74-113(144(225)189-130(89(5)198)150(231)169-78-123(206)177-111(72-97-76-162-85-173-97)142(223)183-107(68-91-32-16-12-17-33-91)136(217)171-80-126(209)192(8)83-128(211)194(117)10)187-140(221)109(70-93-36-20-14-21-37-93)185-138(219)103(42-28-58-167-154(158)159)175-120(203)55-54-119(202)166-60-63-191(7)82-125(208)176-104(43-29-59-168-155(160)161)139(220)186-110(71-94-38-22-15-23-39-94)141(222)188-114-75-122(205)165-57-27-25-41-102(135(157)216)180-147(228)116-45-31-62-197(116)153(234)133(214)106(67-96-48-52-100(201)53-49-96)182-149(230)118(65-88(3)4)195(11)129(212)84-193(9)127(210)81-172-137(218)108(69-92-34-18-13-19-35-92)184-143(224)112(73-98-77-163-86-174-98)178-124(207)79-170-151(232)131(90(6)199)190-145(114)226/h12-23,32-39,46-53,76-77,85-90,101-118,130-131,198-201H,24-31,40-45,54-75,78-84H2,1-11H3,(H2,156,215)(H2,157,216)(H,162,173)(H,163,174)(H,164,204)(H,165,205)(H,166,202)(H,169,231)(H,170,232)(H,171,217)(H,172,218)(H,175,203)(H,176,208)(H,177,206)(H,178,207)(H,179,227)(H,180,228)(H,181,229)(H,182,230)(H,183,223)(H,184,224)(H,185,219)(H,186,220)(H,187,221)(H,188,222)(H,189,225)(H,190,226)(H4,158,159,167)(H4,160,161,168)/t89-,90-,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,130+,131+/m1/s1 YUSUJMUGYDVKGK-XLCKGBBFSA-N 50314092 CHEMBL1090280 IgG receptor FcRn large subunit p51 Homo sapiens 50 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314092&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883969 104148453 CHEMBL1090280 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566588 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCNC(=O)CCNC(=O)CCNC(=O)CN(C)CCNC(=O)CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C160H225N43O38S4/c1-89(2)66-117-149(234)185-105(68-97-44-48-101(206)49-45-97)133(220)155(240)202-63-30-42-115(202)147(232)191-113(137(161)222)85-242-244-159(7,8)135(153(238)193-131(91(5)204)151(236)175-78-124(213)183-111(74-99-76-167-87-179-99)143(228)187-107(70-93-32-20-16-21-33-93)139(224)177-80-127(216)198(12)83-129(218)200(117)14)195-145(230)109(72-95-36-24-18-25-37-95)189-141(226)103(40-28-57-173-157(163)164)181-122(211)53-52-119(208)172-62-65-197(11)82-126(215)171-60-55-121(210)169-59-54-120(209)170-61-56-123(212)182-104(41-29-58-174-158(165)166)142(227)190-110(73-96-38-26-19-27-39-96)146(231)196-136-154(239)194-132(92(6)205)152(237)176-79-125(214)184-112(75-100-77-168-88-180-100)144(229)188-108(71-94-34-22-17-23-35-94)140(225)178-81-128(217)199(13)84-130(219)201(15)118(67-90(3)4)150(235)186-106(69-98-46-50-102(207)51-47-98)134(221)156(241)203-64-31-43-116(203)148(233)192-114(138(162)223)86-243-245-160(136,9)10/h16-27,32-39,44-51,76-77,87-92,103-118,131-132,135-136,204-207H,28-31,40-43,52-75,78-86H2,1-15H3,(H2,161,222)(H2,162,223)(H,167,179)(H,168,180)(H,169,210)(H,170,209)(H,171,215)(H,172,208)(H,175,236)(H,176,237)(H,177,224)(H,178,225)(H,181,211)(H,182,212)(H,183,213)(H,184,214)(H,185,234)(H,186,235)(H,187,228)(H,188,229)(H,189,226)(H,190,227)(H,191,232)(H,192,233)(H,193,238)(H,194,239)(H,195,230)(H,196,231)(H4,163,164,173)(H4,165,166,174)/t91-,92-,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,131+,132+,135-,136-/m1/s1 CWOOKRFILFLASV-MTGNCUGXSA-N 50314094 CHEMBL1090632 IgG receptor FcRn large subunit p51 Homo sapiens 2.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314094&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883971 104148455 CHEMBL1090632 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566589 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NCCNC(=O)CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C148H205N39O34S4/c1-81(2)59-109-137(214)170-97(61-89-43-47-93(190)48-44-89)121(200)143(220)186-57-29-41-107(186)135(212)176-105(125(149)202)77-222-224-147(7,8)123(141(218)178-119(83(5)188)139(216)161-71-113(194)168-103(67-91-69-155-79-165-91)131(208)172-99(63-85-31-19-15-20-32-85)127(204)163-73-115(196)182(11)75-117(198)184(109)13)180-133(210)101(65-87-35-23-17-24-36-87)174-129(206)95(39-27-53-159-145(151)152)157-55-56-158-111(192)51-52-112(193)167-96(40-28-54-160-146(153)154)130(207)175-102(66-88-37-25-18-26-38-88)134(211)181-124-142(219)179-120(84(6)189)140(217)162-72-114(195)169-104(68-92-70-156-80-166-92)132(209)173-100(64-86-33-21-16-22-34-86)128(205)164-74-116(197)183(12)76-118(199)185(14)110(60-82(3)4)138(215)171-98(62-90-45-49-94(191)50-46-90)122(201)144(221)187-58-30-42-108(187)136(213)177-106(126(150)203)78-223-225-148(124,9)10/h15-26,31-38,43-50,69-70,79-84,95-110,119-120,123-124,157,188-191H,27-30,39-42,51-68,71-78H2,1-14H3,(H2,149,202)(H2,150,203)(H,155,165)(H,156,166)(H,158,192)(H,161,216)(H,162,217)(H,163,204)(H,164,205)(H,167,193)(H,168,194)(H,169,195)(H,170,214)(H,171,215)(H,172,208)(H,173,209)(H,174,206)(H,175,207)(H,176,212)(H,177,213)(H,178,218)(H,179,219)(H,180,210)(H,181,211)(H4,151,152,159)(H4,153,154,160)/t83-,84-,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,119+,120+,123-,124-/m1/s1 LXQNZMOUNDTJSQ-DDYKXYLHSA-N 50314095 CHEMBL1090633 IgG receptor FcRn large subunit p51 Homo sapiens 1.6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314095&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883972 104148456 CHEMBL1090633 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566591 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)N(C)CCN(C)C(=O)CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C154H214N40O36S4/c1-85(2)63-113-143(223)175-101(65-93-45-49-97(197)50-46-93)127(209)149(229)193-59-31-43-111(193)141(221)181-109(131(155)211)81-231-233-153(7,8)129(147(227)183-125(87(5)195)145(225)165-75-117(201)173-107(71-95-73-161-83-169-95)137(217)177-103(67-89-33-21-17-22-34-89)133(213)167-77-121(205)189(13)79-123(207)191(113)15)185-139(219)105(69-91-37-25-19-26-38-91)179-135(215)99(41-29-57-163-151(157)158)171-115(199)53-55-119(203)187(11)61-62-188(12)120(204)56-54-116(200)172-100(42-30-58-164-152(159)160)136(216)180-106(70-92-39-27-20-28-40-92)140(220)186-130-148(228)184-126(88(6)196)146(226)166-76-118(202)174-108(72-96-74-162-84-170-96)138(218)178-104(68-90-35-23-18-24-36-90)134(214)168-78-122(206)190(14)80-124(208)192(16)114(64-86(3)4)144(224)176-102(66-94-47-51-98(198)52-48-94)128(210)150(230)194-60-32-44-112(194)142(222)182-110(132(156)212)82-232-234-154(130,9)10/h17-28,33-40,45-52,73-74,83-88,99-114,125-126,129-130,195-198H,29-32,41-44,53-72,75-82H2,1-16H3,(H2,155,211)(H2,156,212)(H,161,169)(H,162,170)(H,165,225)(H,166,226)(H,167,213)(H,168,214)(H,171,199)(H,172,200)(H,173,201)(H,174,202)(H,175,223)(H,176,224)(H,177,217)(H,178,218)(H,179,215)(H,180,216)(H,181,221)(H,182,222)(H,183,227)(H,184,228)(H,185,219)(H,186,220)(H4,157,158,163)(H4,159,160,164)/t87-,88-,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,125+,126+,129-,130-/m1/s1 PVIYYNJGDLWYSH-YUZQCPTASA-N 50314097 CHEMBL1090635::N1,N1'-(ethane-1,2-diyl)bis(N4-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-20-benzyl-3-carbamoyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-N1-methylsuccinamide) IgG receptor FcRn large subunit p51 Homo sapiens 5.2 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314097&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883974 104148458 CHEMBL1090635 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566592 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CN(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C147H203N39O34S4/c1-80(2)56-108-136(213)168-96(58-88-44-48-92(189)49-45-88)120(199)142(219)185-54-30-42-106(185)134(211)174-104(124(148)201)76-221-223-146(7,8)122(140(217)176-118(82(5)187)138(215)158-68-110(191)166-102(64-90-66-154-78-162-90)130(207)170-98(60-84-32-20-16-21-33-84)126(203)160-70-114(195)181(12)74-116(197)183(108)14)178-132(209)100(62-86-36-24-18-25-37-86)172-128(205)94(40-28-52-156-144(150)151)164-112(193)72-180(11)73-113(194)165-95(41-29-53-157-145(152)153)129(206)173-101(63-87-38-26-19-27-39-87)133(210)179-123-141(218)177-119(83(6)188)139(216)159-69-111(192)167-103(65-91-67-155-79-163-91)131(208)171-99(61-85-34-22-17-23-35-85)127(204)161-71-115(196)182(13)75-117(198)184(15)109(57-81(3)4)137(214)169-97(59-89-46-50-93(190)51-47-89)121(200)143(220)186-55-31-43-107(186)135(212)175-105(125(149)202)77-222-224-147(123,9)10/h16-27,32-39,44-51,66-67,78-83,94-109,118-119,122-123,187-190H,28-31,40-43,52-65,68-77H2,1-15H3,(H2,148,201)(H2,149,202)(H,154,162)(H,155,163)(H,158,215)(H,159,216)(H,160,203)(H,161,204)(H,164,193)(H,165,194)(H,166,191)(H,167,192)(H,168,213)(H,169,214)(H,170,207)(H,171,208)(H,172,205)(H,173,206)(H,174,211)(H,175,212)(H,176,217)(H,177,218)(H,178,209)(H,179,210)(H4,150,151,156)(H4,152,153,157)/t82-,83-,94+,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,118+,119+,122-,123-/m1/s1 FYNRYPLZXPBKDJ-MRJVFGEUSA-N 50314098 CHEMBL1090636 IgG receptor FcRn large subunit p51 Homo sapiens 4.7 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314098&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883975 104148459 CHEMBL1090636 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566593 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CC(C)(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C149H206N38O34S4/c1-81(2)57-109-137(214)170-97(59-89-45-49-93(190)50-46-89)121(200)143(220)186-55-31-43-107(186)135(212)176-105(125(150)202)77-222-224-148(9,10)123(141(218)178-119(83(5)188)139(216)160-71-113(194)168-103(65-91-69-156-79-164-91)131(208)172-99(61-85-33-21-17-22-34-85)127(204)162-73-115(196)182(13)75-117(198)184(109)15)180-133(210)101(63-87-37-25-19-26-38-87)174-129(206)95(41-29-53-158-145(152)153)166-111(192)67-147(7,8)68-112(193)167-96(42-30-54-159-146(154)155)130(207)175-102(64-88-39-27-20-28-40-88)134(211)181-124-142(219)179-120(84(6)189)140(217)161-72-114(195)169-104(66-92-70-157-80-165-92)132(209)173-100(62-86-35-23-18-24-36-86)128(205)163-74-116(197)183(14)76-118(199)185(16)110(58-82(3)4)138(215)171-98(60-90-47-51-94(191)52-48-90)122(201)144(221)187-56-32-44-108(187)136(213)177-106(126(151)203)78-223-225-149(124,11)12/h17-28,33-40,45-52,69-70,79-84,95-110,119-120,123-124,188-191H,29-32,41-44,53-68,71-78H2,1-16H3,(H2,150,202)(H2,151,203)(H,156,164)(H,157,165)(H,160,216)(H,161,217)(H,162,204)(H,163,205)(H,166,192)(H,167,193)(H,168,194)(H,169,195)(H,170,214)(H,171,215)(H,172,208)(H,173,209)(H,174,206)(H,175,207)(H,176,212)(H,177,213)(H,178,218)(H,179,219)(H,180,210)(H,181,211)(H4,152,153,158)(H4,154,155,159)/t83-,84-,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,119+,120+,123-,124-/m1/s1 SCSQJZGLKUSLQN-DDYKXYLHSA-N 50314099 CHEMBL1090637::N1,N5-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-20-benzyl-3-carbamoyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-3,3-dimethylpentanediamide IgG receptor FcRn large subunit p51 Homo sapiens 5 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314099&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883976 104148460 CHEMBL1090637 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566594 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)C[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C147H202N38O34S4/c1-79(2)56-108-136(212)168-96(59-88-44-48-92(188)49-45-88)119(197)142(218)184-54-30-42-106(184)134(210)174-104(123(148)199)75-220-222-146(8,9)121(140(216)176-117(82(6)186)138(214)158-69-111(191)165-102(65-90-67-154-77-162-90)130(206)170-98(61-84-32-20-16-21-33-84)126(202)160-71-113(193)180(12)73-115(195)182(108)14)178-132(208)100(63-86-36-24-18-25-37-86)172-128(204)94(40-28-52-156-144(150)151)164-110(190)58-81(5)125(201)167-95(41-29-53-157-145(152)153)129(205)173-101(64-87-38-26-19-27-39-87)133(209)179-122-141(217)177-118(83(7)187)139(215)159-70-112(192)166-103(66-91-68-155-78-163-91)131(207)171-99(62-85-34-22-17-23-35-85)127(203)161-72-114(194)181(13)74-116(196)183(15)109(57-80(3)4)137(213)169-97(60-89-46-50-93(189)51-47-89)120(198)143(219)185-55-31-43-107(185)135(211)175-105(124(149)200)76-221-223-147(122,10)11/h16-27,32-39,44-51,67-68,77-83,94-109,117-118,121-122,186-189H,28-31,40-43,52-66,69-76H2,1-15H3,(H2,148,199)(H2,149,200)(H,154,162)(H,155,163)(H,158,214)(H,159,215)(H,160,202)(H,161,203)(H,164,190)(H,165,191)(H,166,192)(H,167,201)(H,168,212)(H,169,213)(H,170,206)(H,171,207)(H,172,204)(H,173,205)(H,174,210)(H,175,211)(H,176,216)(H,177,217)(H,178,208)(H,179,209)(H4,150,151,156)(H4,152,153,157)/t81-,82+,83+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,117-,118-,121+,122+/m0/s1 VAIDAYMHHSPUQQ-YKLLJAJXSA-N 50314100 (S)-N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-20-benzyl-3-carbamoyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-methylsuccinamide::CHEMBL1090638 IgG receptor FcRn large subunit p51 Homo sapiens 4.6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314100&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883977 104148461 CHEMBL1090638 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566595 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CC[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C148H204N38O34S4/c1-80(2)58-109-137(213)169-97(60-89-45-49-93(189)50-46-89)120(198)143(219)185-56-30-42-107(185)135(211)175-105(124(149)200)76-221-223-147(8,9)122(141(217)177-118(83(6)187)139(215)159-70-112(192)166-103(66-91-68-155-78-163-91)131(207)171-99(62-85-32-20-16-21-33-85)127(203)161-72-114(194)181(12)74-116(196)183(109)14)179-133(209)101(64-87-36-24-18-25-37-87)173-129(205)95(40-28-54-157-145(151)152)165-111(191)53-44-82(5)126(202)168-96(41-29-55-158-146(153)154)130(206)174-102(65-88-38-26-19-27-39-88)134(210)180-123-142(218)178-119(84(7)188)140(216)160-71-113(193)167-104(67-92-69-156-79-164-92)132(208)172-100(63-86-34-22-17-23-35-86)128(204)162-73-115(195)182(13)75-117(197)184(15)110(59-81(3)4)138(214)170-98(61-90-47-51-94(190)52-48-90)121(199)144(220)186-57-31-43-108(186)136(212)176-106(125(150)201)77-222-224-148(123,10)11/h16-27,32-39,45-52,68-69,78-84,95-110,118-119,122-123,187-190H,28-31,40-44,53-67,70-77H2,1-15H3,(H2,149,200)(H2,150,201)(H,155,163)(H,156,164)(H,159,215)(H,160,216)(H,161,203)(H,162,204)(H,165,191)(H,166,192)(H,167,193)(H,168,202)(H,169,213)(H,170,214)(H,171,207)(H,172,208)(H,173,205)(H,174,206)(H,175,211)(H,176,212)(H,177,217)(H,178,218)(H,179,209)(H,180,210)(H4,151,152,157)(H4,153,154,158)/t82-,83+,84+,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,122+,123+/m0/s1 YKZSQGCXTZLZOS-DSRPWJRPSA-N 50314101 (S)-N1,N5-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-20-benzyl-3-carbamoyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-methylpentanediamide::CHEMBL1090639 IgG receptor FcRn large subunit p51 Homo sapiens 5.6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314101&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883978 104148462 CHEMBL1090639 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566596 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CN(C)CCNC(=O)CNC(=O)[C@@H]2CSSC(C)(C)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N2)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C149H208N40O34S4/c1-82(2)58-110-138(216)171-98(60-90-44-48-94(192)49-45-90)122(202)144(222)188-55-30-42-108(188)136(214)177-106(126(151)204)78-224-226-148(7,8)124(142(220)179-120(84(5)190)140(218)162-71-113(195)169-104(66-92-68-156-80-166-92)132(210)174-100(62-86-32-20-16-21-33-86)128(206)164-73-116(198)184(12)76-118(200)186(110)14)182-135(213)103(65-89-38-26-19-27-39-89)176-131(209)97(41-29-53-160-147(154)155)168-115(197)75-183(11)57-54-158-112(194)70-161-130(208)107-79-225-227-149(9,10)125(181-134(212)102(64-88-36-24-18-25-37-88)173-127(205)96(150)40-28-52-159-146(152)153)143(221)180-121(85(6)191)141(219)163-72-114(196)170-105(67-93-69-157-81-167-93)133(211)175-101(63-87-34-22-17-23-35-87)129(207)165-74-117(199)185(13)77-119(201)187(15)111(59-83(3)4)139(217)172-99(61-91-46-50-95(193)51-47-91)123(203)145(223)189-56-31-43-109(189)137(215)178-107/h16-27,32-39,44-51,68-69,80-85,96-111,120-121,124-125,190-193H,28-31,40-43,52-67,70-79,150H2,1-15H3,(H2,151,204)(H,156,166)(H,157,167)(H,158,194)(H,161,208)(H,162,218)(H,163,219)(H,164,206)(H,165,207)(H,168,197)(H,169,195)(H,170,196)(H,171,216)(H,172,217)(H,173,205)(H,174,210)(H,175,211)(H,176,209)(H,177,214)(H,178,215)(H,179,220)(H,180,221)(H,181,212)(H,182,213)(H4,152,153,159)(H4,154,155,160)/t84-,85-,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,120+,121+,124-,125-/m1/s1 LKBLHJOWLIGXFE-VVYPNXECSA-N 50314102 CHEMBL1090640 IgG receptor FcRn large subunit p51 Homo sapiens 3.9 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314102&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883979 104148463 CHEMBL1090640 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566597 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCNC(N)=N)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCC(=O)NCCNCCNC(=O)CNC(=O)[C@@H]1CSSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)C(=O)N2CCC[C@H]2C(=O)N1)[C@@H](C)O InChI=1S/C150H211N41O34S4/c1-83(2)59-111-139(218)174-99(61-91-43-47-95(194)48-44-91)123(204)145(224)190-57-29-41-109(190)137(216)180-107(79-226-228-149(7,8)125(184-135(214)103(65-89-35-23-17-24-36-89)176-127(206)97(151)39-27-51-162-147(153)154)143(222)182-121(85(5)192)141(220)166-73-115(198)172-105(67-93-69-158-81-170-93)133(212)178-101(63-87-31-19-15-20-32-87)129(208)168-75-117(200)186(11)77-119(202)188(111)13)131(210)164-71-113(196)160-55-53-157-54-56-161-114(197)72-165-132(211)108-80-227-229-150(9,10)126(185-136(215)104(66-90-37-25-18-26-38-90)177-128(207)98(152)40-28-52-163-148(155)156)144(223)183-122(86(6)193)142(221)167-74-116(199)173-106(68-94-70-159-82-171-94)134(213)179-102(64-88-33-21-16-22-34-88)130(209)169-76-118(201)187(12)78-120(203)189(14)112(60-84(3)4)140(219)175-100(62-92-45-49-96(195)50-46-92)124(205)146(225)191-58-30-42-110(191)138(217)181-108/h15-26,31-38,43-50,69-70,81-86,97-112,121-122,125-126,157,192-195H,27-30,39-42,51-68,71-80,151-152H2,1-14H3,(H,158,170)(H,159,171)(H,160,196)(H,161,197)(H,164,210)(H,165,211)(H,166,220)(H,167,221)(H,168,208)(H,169,209)(H,172,198)(H,173,199)(H,174,218)(H,175,219)(H,176,206)(H,177,207)(H,178,212)(H,179,213)(H,180,216)(H,181,217)(H,182,222)(H,183,223)(H,184,214)(H,185,215)(H4,153,154,162)(H4,155,156,163)/t85-,86-,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,121+,122+,125-,126-/m1/s1 GKCNAQLLJFDJQV-FSXZOGRCSA-N 50314103 (R,S,S,3R,3'R,8R,8'R,11S,11'S,17S,17'S,20S,20'S,29S,29'S,32S,32'S,38aS,38a'S)-N,N'-(2,2'-(2,2'-azanediylbis(ethane-2,1-diyl)bis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-amino-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacon::CHEMBL1090968 IgG receptor FcRn large subunit p51 Homo sapiens 4.2 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314103&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883980 104148464 CHEMBL1090968 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566598 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccc(cc2)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3ccc(cc3)N=C(N)N)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C136H192N38O32S4/c1-71(2)55-97-123(199)159-87(57-79-37-45-83(177)46-38-79)109(187)129(205)173-53-23-31-95(173)121(197)163-93(113(137)189)69-207-209-135(7,8)111(127(203)165-107(73(5)175)125(201)149-63-101(181)157-89(61-77-33-41-81(42-34-77)153-133(143)144)115(191)151-65-103(183)169(11)67-105(185)171(97)13)167-119(195)91(59-75-25-17-15-18-26-75)161-117(193)85(29-21-51-147-131(139)140)155-99(179)49-50-100(180)156-86(30-22-52-148-132(141)142)118(194)162-92(60-76-27-19-16-20-28-76)120(196)168-112-128(204)166-108(74(6)176)126(202)150-64-102(182)158-90(62-78-35-43-82(44-36-78)154-134(145)146)116(192)152-66-104(184)170(12)68-106(186)172(14)98(56-72(3)4)124(200)160-88(58-80-39-47-84(178)48-40-80)110(188)130(206)174-54-24-32-96(174)122(198)164-94(114(138)190)70-208-210-136(112,9)10/h15-20,25-28,33-48,71-74,85-98,107-108,111-112,175-178H,21-24,29-32,49-70H2,1-14H3,(H2,137,189)(H2,138,190)(H,149,201)(H,150,202)(H,151,191)(H,152,192)(H,155,179)(H,156,180)(H,157,181)(H,158,182)(H,159,199)(H,160,200)(H,161,193)(H,162,194)(H,163,197)(H,164,198)(H,165,203)(H,166,204)(H,167,195)(H,168,196)(H4,139,140,147)(H4,141,142,148)(H4,143,144,153)(H4,145,146,154)/t73-,74-,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,107+,108+,111-,112-/m1/s1 OOPGUWBDBVXBMU-MCJNUYKLSA-N 50314104 CHEMBL1090969::N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,26S,29S,35aS)-3-carbamoyl-17-(4-guanidinobenzyl)-29-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-26-isobutyl-7,7,22,25-tetramethyl-1,9,12,15,18,21,24,27,30,31-decaoxodotriacontahydro-1H-pyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30]dithianonaazacyclotritriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)succinamide IgG receptor FcRn large subunit p51 Homo sapiens 20 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314104&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883981 104148465 CHEMBL1090969 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566599 CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CSSC2(C)C)C(N)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O InChI=1S/C146H200N38O34S4/c1-79(2)57-107-135(211)167-95(59-87-43-47-91(187)48-44-87)119(197)141(217)183-55-29-41-105(183)133(209)173-103(123(147)199)75-219-221-145(7,8)121(139(215)175-117(81(5)185)137(213)157-69-111(191)165-101(65-89-67-153-77-161-89)129(205)169-97(61-83-31-19-15-20-32-83)125(201)159-71-113(193)179(11)73-115(195)181(107)13)177-131(207)99(63-85-35-23-17-24-36-85)171-127(203)93(39-27-53-155-143(149)150)163-109(189)51-52-110(190)164-94(40-28-54-156-144(151)152)128(204)172-100(64-86-37-25-18-26-38-86)132(208)178-122-140(216)176-118(82(6)186)138(214)158-70-112(192)166-102(66-90-68-154-78-162-90)130(206)170-98(62-84-33-21-16-22-34-84)126(202)160-72-114(194)180(12)74-116(196)182(14)108(58-80(3)4)136(212)168-96(60-88-45-49-92(188)50-46-88)120(198)142(218)184-56-30-42-106(184)134(210)174-104(124(148)200)76-220-222-146(122,9)10/h15-26,31-38,43-50,67-68,77-82,93-108,117-118,121-122,185-188H,27-30,39-42,51-66,69-76H2,1-14H3,(H2,147,199)(H2,148,200)(H,153,161)(H,154,162)(H,157,213)(H,158,214)(H,159,201)(H,160,202)(H,163,189)(H,164,190)(H,165,191)(H,166,192)(H,167,211)(H,168,212)(H,169,205)(H,170,206)(H,171,203)(H,172,204)(H,173,209)(H,174,210)(H,175,215)(H,176,216)(H,177,207)(H,178,208)(H4,149,150,155)(H4,151,152,156)/t81-,82-,93+,94+,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,105+,106+,107+,108+,117+,118+,121-,122-/m1/s1 XJMSSJXEWKKJAD-UBJADOFFSA-N 50314105 CHEMBL1090970::N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-20-benzyl-3-carbamoyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)succinamide IgG receptor FcRn large subunit p51 Homo sapiens 2.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314105&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883982 104148466 CHEMBL1090970 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566600 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C85H117N25O23S2/c1-44(2)30-55-77(126)102-54(31-49-21-23-51(113)24-22-49)71(120)84(133)110-29-13-20-63(110)82(131)107-60(80(129)105-59(35-65(87)115)74(123)96-40-69(119)109-28-12-19-62(109)72(88)121)41-134-135-42-61(106-78(127)57(33-48-16-9-6-10-17-48)104-75(124)52(18-11-27-92-85(89)90)101-76(125)53(98-46(4)112)25-26-64(86)114)81(130)108-70(45(3)111)83(132)95-39-68(118)100-58(34-50-36-91-43-97-50)79(128)103-56(32-47-14-7-5-8-15-47)73(122)94-37-66(116)93-38-67(117)99-55/h5-10,14-17,21-24,36,43-45,52-63,70,111,113H,11-13,18-20,25-35,37-42H2,1-4H3,(H2,86,114)(H2,87,115)(H2,88,121)(H,91,97)(H,93,116)(H,94,122)(H,95,132)(H,96,123)(H,98,112)(H,99,117)(H,100,118)(H,101,125)(H,102,126)(H,103,128)(H,104,124)(H,105,129)(H,106,127)(H,107,131)(H,108,130)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+/m1/s1 ZSZFDFFMKORUQF-GWPUDWGZSA-N 50314106 (S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-3-((S)-4-amino-1-(2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethylamino)-1,4-dioxobutan-2-ylcarbamoyl)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-acetamidopentanediamide::CHEMBL1089944 IgG receptor FcRn large subunit p51 Homo sapiens 40000 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314106&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883953 104148467 CHEMBL1089944 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566601 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C85H117N25O23S2/c1-44(2)30-55-77(126)102-54(31-49-21-23-51(113)24-22-49)71(120)84(133)110-29-13-20-63(110)82(131)107-60(80(129)105-59(35-65(87)115)74(123)96-40-69(119)109-28-12-19-62(109)72(88)121)41-134-135-42-61(106-78(127)57(33-48-16-9-6-10-17-48)104-75(124)52(18-11-27-92-85(89)90)101-76(125)53(98-46(4)112)25-26-64(86)114)81(130)108-70(45(3)111)83(132)95-39-68(118)100-58(34-50-36-91-43-97-50)79(128)103-56(32-47-14-7-5-8-15-47)73(122)94-37-66(116)93-38-67(117)99-55/h5-10,14-17,21-24,36,43-45,52-63,70,111,113H,11-13,18-20,25-35,37-42H2,1-4H3,(H2,86,114)(H2,87,115)(H2,88,121)(H,91,97)(H,93,116)(H,94,122)(H,95,132)(H,96,123)(H,98,112)(H,99,117)(H,100,118)(H,101,125)(H,102,126)(H,103,128)(H,104,124)(H,105,129)(H,106,127)(H,107,131)(H,108,130)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+/m1/s1 ZSZFDFFMKORUQF-GWPUDWGZSA-N 50314106 (S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-3-((S)-4-amino-1-(2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethylamino)-1,4-dioxobutan-2-ylcarbamoyl)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-acetamidopentanediamide::CHEMBL1089944 IgG receptor FcRn large subunit p51 Homo sapiens 5300 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314106&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883953 104148467 CHEMBL1089944 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566602 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O InChI=1S/C85H117N25O23S2/c1-44(2)30-55-77(126)102-54(31-49-21-23-51(113)24-22-49)71(120)84(133)110-29-13-20-63(110)82(131)107-60(80(129)105-59(35-65(87)115)74(123)96-40-69(119)109-28-12-19-62(109)72(88)121)41-134-135-42-61(106-78(127)57(33-48-16-9-6-10-17-48)104-75(124)52(18-11-27-92-85(89)90)101-76(125)53(98-46(4)112)25-26-64(86)114)81(130)108-70(45(3)111)83(132)95-39-68(118)100-58(34-50-36-91-43-97-50)79(128)103-56(32-47-14-7-5-8-15-47)73(122)94-37-66(116)93-38-67(117)99-55/h5-10,14-17,21-24,36,43-45,52-63,70,111,113H,11-13,18-20,25-35,37-42H2,1-4H3,(H2,86,114)(H2,87,115)(H2,88,121)(H,91,97)(H,93,116)(H,94,122)(H,95,132)(H,96,123)(H,98,112)(H,99,117)(H,100,118)(H,101,125)(H,102,126)(H,103,128)(H,104,124)(H,105,129)(H,106,127)(H,107,131)(H,108,130)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+/m1/s1 ZSZFDFFMKORUQF-GWPUDWGZSA-N 50314106 (S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-3-((S)-4-amino-1-(2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethylamino)-1,4-dioxobutan-2-ylcarbamoyl)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontin-8-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-acetamidopentanediamide::CHEMBL1089944 IgG receptor FcRn large subunit p51 Homo sapiens 37000 7.4 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314106&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883953 104148467 CHEMBL1089944 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566603 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O InChI=1S/C69H93N19O17S2/c1-37(2)25-47-62(99)82-46(26-42-19-21-44(91)22-20-42)58(95)68(105)88-24-12-18-53(88)66(103)85-51(59(70)96)34-106-107-35-52(86-63(100)49(28-41-15-9-6-10-16-41)84-61(98)45(79-39(4)90)17-11-23-74-69(71)72)65(102)87-57(38(3)89)67(104)77-33-56(94)81-50(29-43-30-73-36-78-43)64(101)83-48(27-40-13-7-5-8-14-40)60(97)76-31-54(92)75-32-55(93)80-47/h5-10,13-16,19-22,30,36-38,45-53,57,89,91H,11-12,17-18,23-29,31-35H2,1-4H3,(H2,70,96)(H,73,78)(H,75,92)(H,76,97)(H,77,104)(H,79,90)(H,80,93)(H,81,94)(H,82,99)(H,83,101)(H,84,98)(H,85,103)(H,86,100)(H,87,102)(H4,71,72,74)/t38-,45+,46+,47+,48+,49+,50+,51+,52+,53+,57+/m1/s1 KCRCHIPXFWUNGB-XMQMWVRNSA-N 50314107 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089945 IgG receptor FcRn large subunit p51 Homo sapiens 37000 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314107&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883954 104148468 CHEMBL1089945 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19 50566604 CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O InChI=1S/C69H93N19O17S2/c1-37(2)25-47-62(99)82-46(26-42-19-21-44(91)22-20-42)58(95)68(105)88-24-12-18-53(88)66(103)85-51(59(70)96)34-106-107-35-52(86-63(100)49(28-41-15-9-6-10-16-41)84-61(98)45(79-39(4)90)17-11-23-74-69(71)72)65(102)87-57(38(3)89)67(104)77-33-56(94)81-50(29-43-30-73-36-78-43)64(101)83-48(27-40-13-7-5-8-14-40)60(97)76-31-54(92)75-32-55(93)80-47/h5-10,13-16,19-22,30,36-38,45-53,57,89,91H,11-12,17-18,23-29,31-35H2,1-4H3,(H2,70,96)(H,73,78)(H,75,92)(H,76,97)(H,77,104)(H,79,90)(H,80,93)(H,81,94)(H,82,99)(H,83,101)(H,84,98)(H,85,103)(H,86,100)(H,87,102)(H4,71,72,74)/t38-,45+,46+,47+,48+,49+,50+,51+,52+,53+,57+/m1/s1 KCRCHIPXFWUNGB-XMQMWVRNSA-N 50314107 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089945 IgG receptor FcRn large subunit p51 Homo sapiens 5900 6 ChEMBL 10.1021/jm901128z 10.7270/Q23R0T1H 20092334 McDonnell, KA; Low, SC; Hoehn, T; Donnelly, R; Palmieri, H; Fraley, C; Sakorafas, P; Mezo, AR Syntonix Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004135&target=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314107&enzyme=IgG+receptor+FcRn+large+subunit+p51&column=ki&startPg=0&Increment=50&submit=Search 46883954 104148468 CHEMBL1089945 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA 1EXU,3M17,3M1B,4K71,4N0F,4N0U,5BJT,5BXF,5WHK,6C97,6C98,6C99,6FGB,6ILM,6LA6,6LA7,6QIO,6QIP,6WNA,6WOL,7B5F,7C9V,7Q15,7XXA IgG receptor FcRn large subunit p51 FCGRN_HUMAN P55899 Q5HYM5 Q9HBV7 Q9NZ19