BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50388330 CC(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) BZKPWHYZMXOIDC-UHFFFAOYSA-N 10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1 Carbonic anhydrase Saccharomyces cerevisiae 82 ChEMBL 10.1016/j.bmc.2015.05.029 10.7270/Q20V8FK8 26068018 Pinard, MA; Lotlikar, SR; Boone, CD; Vullo, D; Supuran, CT; Patrauchan, MA; McKenna, R University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10880&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search AZM 4YGF,3W6H,3CZV,3V2J,3V2M,4G7A,4X5S,6QEB,1YDB,1YDA,1YDD,4LU3,3UCJ,4UOV,2UY4,4K0S,7COJ,4XIW,3HS4,4G0C,1DMY,1AZM,1JD0,1RJ6,1ZSB,2H4N,5JN8,8DYQ,3IAI,6IM3,5NEK,3DC3,2XTK,6MWJ,3ML5,6YMA 1986 46511450 27690 CHEMBL20 DB00819 6792 C06805 ZINC03813042 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439457 CC(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) BZKPWHYZMXOIDC-UHFFFAOYSA-N 10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1 Carbonic anhydrase Saccharomyces cerevisiae 16000 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10880&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search AZM 4YGF,3W6H,3CZV,3V2J,3V2M,4G7A,4X5S,6QEB,1YDB,1YDA,1YDD,4LU3,3UCJ,4UOV,2UY4,4K0S,7COJ,4XIW,3HS4,4G0C,1DMY,1AZM,1JD0,1RJ6,1ZSB,2H4N,5JN8,8DYQ,3IAI,6IM3,5NEK,3DC3,2XTK,6MWJ,3ML5,6YMA 1986 46511450 27690 CHEMBL20 DB00819 6792 C06805 ZINC03813042 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439458 CCOc1ccc2nc(sc2c1)S(N)(=O)=O InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) OUZWUKMCLIBBOG-UHFFFAOYSA-N 10882 6-ethoxy-1,3-benzothiazole-2-sulfonamide::CHEMBL18::Ethamide::Ethoxazolamide::Ethoxzolamide::Ethoxzolamide (EZA)::Ethoxzolamide, EZM::Sulfonamide, 3::US10172837, Ethoxyzolamide::sulfonamide 3 Carbonic anhydrase Saccharomyces cerevisiae 16000 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10882&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search EZL 3DD0,5JN9,3CAJ,3MDZ,6BCC,3DCW,6QL2,5TT3,6MWI 3295 46511452 101096 CHEMBL18 DB00311 6814 ZINC00056721 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439462 NS(N)(=O)=O InChI=1S/H4N2O2S/c1-5(2,3)4/h(H4,1,2,3,4) NVBFHJWHLNUMCV-UHFFFAOYSA-N 26995 CHEMBL355001::H2NSO2NH2::sulfamamide::sulfamide::sulfamoylamine Carbonic anhydrase Saccharomyces cerevisiae 8700 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26995&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search FUS 6D2N 82267 57298705 48266 CHEMBL355001 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439472 O[As](O)(=O)c1ccccc1 InChI=1S/C6H7AsO3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H,(H2,8,9,10) LVKZSFMYNWRPJX-UHFFFAOYSA-N 26997 CHEMBL364571::PhAsO3H2::benzenarsonic acid::benzenearsonic acid::phenylarsonic acid Carbonic anhydrase Saccharomyces cerevisiae 40000 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26997&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 7365 57298707 29851 CHEMBL364571 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439473 OB(O)c1ccccc1 InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H HXITXNWTGFUOAU-UHFFFAOYSA-N 26996 CHEMBL21485::PhB(OH)2::Phenyl-boronic acid::Phenylboronic acid, 22::benzeneboronic acid::phenylboranediol::phenylboronic acid Carbonic anhydrase Saccharomyces cerevisiae 38200000 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26996&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search PBC 6VIM,1JU3,6UQU,4OB0,2A32 66827 57298706 44923 CHEMBL21485 DB01795 C16200 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50439474 NS(O)(=O)=O InChI=1S/H3NO3S/c1-5(2,3)4/h(H3,1,2,3,4) IIACRCGMVDHOTQ-UHFFFAOYSA-N 26994 CHEMBL68253::H2NSO3H::sulfamic acid Carbonic anhydrase Saccharomyces cerevisiae 840000 ChEMBL 10.1016/j.bmcl.2008.10.100 10.7270/Q26D5SV7 18993072 Isik, S; Kockar, F; Arslan, O; Guler, OO; Innocenti, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26994&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 5987 57298704 48266 CHEMBL68253 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878535 NCc1ccc(cc1)S(N)(=O)=O InChI=1S/C7H10N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,11) TYMRLRRVMHJFTF-UHFFFAOYSA-N 10860 4-(aminomethyl)benzene-1-sulfonamide::CHEMBL419::MAFENIDE::aromatic sulfonamide compound 6::aromatic/heteroaromatic sulfonamide 5::hCA inhibitor, 9 Carbonic anhydrase Saccharomyces cerevisiae 433 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10860&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 6LH 5JNC 3998 46511432 CHEMBL419 DB06795 C07106 ZINC00001644 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878536 NCCc1ccc(cc1)S(N)(=O)=O InChI=1S/C8H12N2O2S/c9-6-5-7-1-3-8(4-2-7)13(10,11)12/h1-4H,5-6,9H2,(H2,10,11,12) FXNSVEQMUYPYJS-UHFFFAOYSA-N 10861 4-(2-aminoethyl)benzene-1-sulfonamide::CHEMBL7087::aromatic sulfonamide compound 7::aromatic/heteroaromatic sulfonamide 6 Carbonic anhydrase Saccharomyces cerevisiae 163 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10861&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search ZYX 2NNG 169682 46511433 CHEMBL7087 DB08782 ZINC00056629 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878537 Nc1ccc(cc1F)S(N)(=O)=O InChI=1S/C6H7FN2O2S/c7-5-3-4(12(9,10)11)1-2-6(5)8/h1-3H,8H2,(H2,9,10,11) HVFBADWBKHAPKV-UHFFFAOYSA-N 10862 4-Amino-3-fluorobenzenesulfonamide::4-amino-3-fluorobenzene-1-sulfonamide::CHEMBL6853::aromatic/heteroaromatic sulfonamide 7::halogenosulfanilamide deriv. 5b Carbonic anhydrase Saccharomyces cerevisiae 389 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10862&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 4687472 46511434 CHEMBL6853 ZINC06925827 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878538 Nc1ccc(cc1Cl)S(N)(=O)=O InChI=1S/C6H7ClN2O2S/c7-5-3-4(12(9,10)11)1-2-6(5)8/h1-3H,8H2,(H2,9,10,11) LFIOFZKZCDMGFG-UHFFFAOYSA-N 10863 4-Amino-3-chlorobenzenesulfonamide::4-amino-3-chlorobenzene-1-sulfonamide::CHEMBL7092::aromatic/heteroaromatic sulfonamide 8::halogenosulfanilamide deriv. 5c Carbonic anhydrase Saccharomyces cerevisiae 457 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10863&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 1502014 46511435 CHEMBL7092 ZINC01420707 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878539 Nc1ccc(cc1Br)S(N)(=O)=O InChI=1S/C6H7BrN2O2S/c7-5-3-4(12(9,10)11)1-2-6(5)8/h1-3H,8H2,(H2,9,10,11) KQEVQYJWCZRLTJ-UHFFFAOYSA-N 10864 4-Amino-3-bromobenzenesulfonamide::4-amino-3-bromobenzene-1-sulfonamide::CHEMBL6724::aromatic/heteroaromatic sulfonamide 9::halogenosulfanilamide deriv. 5d Carbonic anhydrase Saccharomyces cerevisiae 248 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10864&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 3526523 46511436 CHEMBL6724 ZINC12522340 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878540 Nc1ccc(cc1I)S(N)(=O)=O InChI=1S/C6H7IN2O2S/c7-5-3-4(12(9,10)11)1-2-6(5)8/h1-3H,8H2,(H2,9,10,11) HCODCRHNVCTCTR-UHFFFAOYSA-N 10865 4-Amino-3-iodobenzenesulfonamide::4-amino-3-iodobenzene-1-sulfonamide::CHEMBL268177::aromatic/heteroaromatic sulfonamide 10::halogenosulfanilamide deriv. 5e Carbonic anhydrase Saccharomyces cerevisiae 976 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10865&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 9861037 46511437 CHEMBL268177 ZINC13442499 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878541 Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F InChI=1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17) KRVABEGPNKGLOT-UHFFFAOYSA-N 10866 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide::CHEMBL418::aromatic/heteroaromatic sulfonamide 11 Carbonic anhydrase Saccharomyces cerevisiae 223 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10866&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search I7C 2POW 69561 46511438 CHEMBL418 ZINC01676919 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878542 Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14) IHJCXVZDYSXXFT-UHFFFAOYSA-N 10867 4-amino-6-chlorobenzene-1,3-disulfonamide::CHEMBL266240::aromatic/heteroaromatic sulfonamide 12 Carbonic anhydrase Saccharomyces cerevisiae 169 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10867&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search I7B 7NML,2POV,3L14 67136 46511439 CHEMBL266240 C07460 ZINC01530783 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878543 Nc1nnc(s1)S(N)(=O)=O InChI=1S/C2H4N4O2S2/c3-1-5-6-2(9-1)10(4,7)8/h(H2,3,5)(H2,4,7,8) VGMVBPQOACUDRU-UHFFFAOYSA-N 10868 1,3,4-Thiadiazole-2-sulfonamide, 6::1,3,4-thiadiazole-2-sulfonamide 15::5-Amino-1,3,4-thiadiazole-2-sulphonamide (1)::5-amino-1,3,4-thiadiazole-2-sulfonamide::CHEMBL265674::aromatic/heteroaromatic sulfonamide 13 Carbonic anhydrase Saccharomyces cerevisiae 447 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10868&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 1SA 2HNC,5TUO 84724 46509349 CHEMBL265674 ZINC16969869 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878544 Cn1nc(sc1=N)S(N)(=O)=O InChI=1S/C3H6N4O2S2/c1-7-2(4)10-3(6-7)11(5,8)9/h4H,1H3,(H2,5,8,9) BWSMJWLWXNCHHP-UHFFFAOYSA-N 10869 5-imino-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide::CHEMBL6753::aromatic/heteroaromatic sulfonamide 14 Carbonic anhydrase Saccharomyces cerevisiae 360 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10869&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 5172475 46511440 CHEMBL6753 ZINC05423825 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878545 Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C8H9N5O4S3/c9-5-1-3-6(4-2-5)20(16,17)13-7-11-12-8(18-7)19(10,14)15/h1-4H,9H2,(H,11,13)(H2,10,14,15) BDLSLORLEPSOGW-UHFFFAOYSA-N 10870 2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfonamide::Aminobenzolamide 12::CHEMBL268439::aminobenzolamide 17a::aminobenzolamide deriv. 43::aromatic/heteroaromatic sulfonamide 15 Carbonic anhydrase Saccharomyces cerevisiae 124 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10870&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 134560 46511441 CHEMBL268439 ZINC05579307 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878546 Nc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O InChI=1S/C13H15N3O4S2/c14-11-3-7-13(8-4-11)22(19,20)16-9-10-1-5-12(6-2-10)21(15,17)18/h1-8,16H,9,14H2,(H2,15,17,18) HHCXOFYGBAPOJR-UHFFFAOYSA-N 10871 4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide::CHEMBL266026::aromatic/heteroaromatic sulfonamide 16 Carbonic anhydrase Saccharomyces cerevisiae 166 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10871&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 4422372 46511442 CHEMBL266026 ZINC06392199 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878547 Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O InChI=1S/C14H17N3O4S2/c15-12-3-7-14(8-4-12)23(20,21)17-10-9-11-1-5-13(6-2-11)22(16,18)19/h1-8,17H,9-10,15H2,(H2,16,18,19) WODATDPNMUWSHD-UHFFFAOYSA-N 10872 4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide::CHEMBL7146::aromatic/heteroaromatic sulfonamide 17 Carbonic anhydrase Saccharomyces cerevisiae 154 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10872&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 9998322 46511443 CHEMBL7146 ZINC13488273 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878548 Nc1nccc(Nc2ccc(cc2)S(N)(=O)=O)n1 InChI=1S/C10H11N5O2S/c11-10-13-6-5-9(15-10)14-7-1-3-8(4-2-7)18(12,16)17/h1-6H,(H2,12,16,17)(H3,11,13,14,15) QOAXQANKSMHFKJ-UHFFFAOYSA-N 10873 4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide::CHEMBL6633::US9616064, Compound 1aa::aromatic/heteroaromatic sulfonamide 18 Carbonic anhydrase Saccharomyces cerevisiae 15.1 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10873&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 31036 46511444 CHEMBL6633 ZINC00056465 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878549 NS(=O)(=O)c1nnc(s1)-c1ccccc1Cl InChI=1S/C8H6ClN3O2S2/c9-6-4-2-1-3-5(6)7-11-12-8(15-7)16(10,13)14/h1-4H,(H2,10,13,14) PZVGOWIIHCUHAO-UHFFFAOYSA-N 10875 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide::CHEMBL360356::Chlorzolamide, CHL::JMC522226 Compound 19::JMC523116 Compound 19::aromatic/heteroaromatic sulfonamide 20 Carbonic anhydrase Saccharomyces cerevisiae 565 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10875&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search D9Z 4K0T,3D9Z,3DCC 165323 46511446 CHEMBL360356 DB07632 ZINC06095534 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878550 NS(=O)(=O)c1ccc(CO)cc1 InChI=1S/C7H9NO3S/c8-12(10,11)7-3-1-6(5-9)2-4-7/h1-4,9H,5H2,(H2,8,10,11) UULCVOIRJRJPQS-UHFFFAOYSA-N 10876 4-(hydroxymethyl)benzene-1-sulfonamide::CHEMBL6919::JMC522226 Compound 20::JMC523116 Compound 20::aromatic/heteroaromatic sulfonamide 21 Carbonic anhydrase Saccharomyces cerevisiae 8970 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10876&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 10081162 46511447 CHEMBL6919 ZINC13442503 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878551 NS(=O)(=O)c1ccc(CCO)cc1 InChI=1S/C8H11NO3S/c9-13(11,12)8-3-1-7(2-4-8)5-6-10/h1-4,10H,5-6H2,(H2,9,11,12) RYKHXKKLCRPAJP-UHFFFAOYSA-N 10877 4-(2-hydroxyethyl)benzene-1-sulfonamide::CHEMBL6784::JMC522226 Compound 21::JMC523116 Compound 21::aromatic/heteroaromatic sulfonamide 22 Carbonic anhydrase Saccharomyces cerevisiae 7540 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10877&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search S2O 6RG5,4YYT 10375558 46511448 CHEMBL6784 ZINC13442505 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878552 NS(=O)(=O)c1ccc(cc1)C(O)=O InChI=1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) UCAGLBKTLXCODC-UHFFFAOYSA-N 4703 4-carboxybenzenesulfonamide 1::4-sulfamoylbenzoic acid::Benzoic Acid deriv. 31::CHEMBL414::JMC522226 Compound 22::JMC523116 Compound 22::JMC52646 Compound 23::aromatic/heteroaromatic sulfonamide 23 Carbonic anhydrase Saccharomyces cerevisiae 14500 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4703&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 4SO 6RFH,3R4G,5RSM 8739 8034358 CHEMBL414 ZINC00001099 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878553 CC(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) BZKPWHYZMXOIDC-UHFFFAOYSA-N 10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1 Carbonic anhydrase Saccharomyces cerevisiae 82.6 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10880&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search AZM 4YGF,3W6H,3CZV,3V2J,3V2M,4G7A,4X5S,6QEB,1YDB,1YDA,1YDD,4LU3,3UCJ,4UOV,2UY4,4K0S,7COJ,4XIW,3HS4,4G0C,1DMY,1AZM,1JD0,1RJ6,1ZSB,2H4N,5JN8,8DYQ,3IAI,6IM3,5NEK,3DC3,2XTK,6MWJ,3ML5,6YMA 1986 46511450 27690 CHEMBL20 DB00819 6792 C06805 ZINC03813042 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878554 CC(=O)N=c1sc(nn1C)S(N)(=O)=O InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) FLOSMHQXBMRNHR-UHFFFAOYSA-N 10881 CHEMBL288100::MZA3::Methazolamide::Methazolamide (MZA)::Methazolamide, MZA::N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide::Sulfonamide, 2::cid_4100::sulfonamide 2 Carbonic anhydrase Saccharomyces cerevisiae 119 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10881&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search MZM 4K0Z,4YHA,5KU6,1BZM,5C8I,3DAZ,3DCS 4100 46511451 CHEMBL288100 6828 ZINC12503151 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878555 CCOc1ccc2nc(sc2c1)S(N)(=O)=O InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) OUZWUKMCLIBBOG-UHFFFAOYSA-N 10882 6-ethoxy-1,3-benzothiazole-2-sulfonamide::CHEMBL18::Ethamide::Ethoxazolamide::Ethoxzolamide::Ethoxzolamide (EZA)::Ethoxzolamide, EZM::Sulfonamide, 3::US10172837, Ethoxyzolamide::sulfonamide 3 Carbonic anhydrase Saccharomyces cerevisiae 98.4 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10882&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search EZL 3DD0,5JN9,3CAJ,3MDZ,6BCC,3DCW,6QL2,5TT3,6MWI 3295 46511452 101096 CHEMBL18 DB00311 6814 ZINC00056721 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878556 NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) GJQPMPFPNINLKP-UHFFFAOYSA-N 10883 4,5-dichlorobenzene-1,3-disulfonamide::CHEMBL17::Dichlorophenamide::Dichlorophenamide (DCP)::Dichlorophenamide, DCP::Sulfonamide, 4::US10172837, Dichlorphenamide::sulfonamide 4 Carbonic anhydrase Saccharomyces cerevisiae 103 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10883&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search I7A 2POU 3038 46511453 101085 CHEMBL17 DB01144 6807 C07459 ZINC00896918 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878557 CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1 IAVUPMFITXYVAF-XPUUQOCRSA-N 10884 (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1,7-thieno[2,3-b]thiopyran-6-sulfonamide::Dorzolamide (DRZ)::Dorzolamide (DZA) Carbonic anhydrase Saccharomyces cerevisiae 110 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10884&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search ETS 4M2W,4M2U,4K13,3FW3,6BC9,1CIL 5284549 46511454 4702 DB00869 6810 C06969 ZINC01530621 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878558 CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1 HCRKCZRJWPKOAR-JTQLQIEISA-N 10885 (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide::(R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-E)-1,2-thiazine-6-sulfonamide 1,1-dioxide::AL-4862::Azopt::Brinzolamide (BRZ)::brinzolamide Carbonic anhydrase Saccharomyces cerevisiae 114 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10885&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search BZ1 3ZNC,4M2V,4M2R,6BBS 68844 46511455 3176 DB01194 6797 C07760 ZINC03953037 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878559 NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccccc2)s1 InChI=1S/C8H8N4O4S3/c9-18(13,14)8-11-10-7(17-8)12-19(15,16)6-4-2-1-3-5-6/h1-5H,(H,10,12)(H2,9,13,14) PWDGTQXZLNDOKS-UHFFFAOYSA-N 10886 2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide::BZA1::Benzolamide::Benzolamide (BZA)::CHEMBL73962 Carbonic anhydrase Saccharomyces cerevisiae 111 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10886&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 3DB 3D8W,3DBU 18794 46511456 CHEMBL73962 DB07050 6920 ZINC04194731 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878560 CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1 KJADKKWYZYXHBB-XBWDGYHZSA-N 10887 Sulfamate 7::Topiramate (TPM)::US11535599, Example topiramate::[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate Carbonic anhydrase Saccharomyces cerevisiae 110 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10887&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search TOR 3LXE,3HKU,5JNA 5284627 46511457 63631 DB00273 6849 C07502 ZINC01530804 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878561 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride Carbonic anhydrase Saccharomyces cerevisiae 124 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878562 NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) SETFNECMODOHTO-UHFFFAOYSA-N 10890 1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide::CHEMBL77517::Compound 6::E7070::Indisulam (IND)::Sulfonamide, 7 Carbonic anhydrase Saccharomyces cerevisiae 133 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10890&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search EF6 6UD7,6SJ7,6Q0W 216468 46511460 CHEMBL77517 7046 ZINC00600748 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878563 NS(=O)(=O)Cc1noc2ccccc12 InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) UBQNRHZMVUUOMG-UHFFFAOYSA-N 10888 1,2-benzoxazol-3-ylmethanesulfonamide::CHEMBL750::SPR_2::US10172837, Zonisamide::Zonisamide::Zonisamide (ZNA)::Zonisamide (ZNS)::Zonisamide, 1::Zonisamide, ZNS Carbonic anhydrase Saccharomyces cerevisiae 106 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10888&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search ZON 3PO7 5734 46511458 10127 CHEMBL750 DB00909 7047 C07504 ZINC00004321 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878564 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Carbonic anhydrase Saccharomyces cerevisiae 108 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878565 Cc1onc(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20) LNPDTQAFDNKSHK-UHFFFAOYSA-N 13063 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide::Bextra::CHEMBL865::VLX::Valdecoxib::cid_119607 Carbonic anhydrase Saccharomyces cerevisiae 654 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13063&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search COX 2AW1 119607 46513481 63634 CHEMBL865 DB00580 2894 ZINC00006694 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878566 NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16) HMHVCUVYZFYAJI-UHFFFAOYSA-N 26999 4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonamide::CHEMBL328560::Contravul::Ospolot::Sulthiame (SLT)::Sulthiame, 2 Carbonic anhydrase Saccharomyces cerevisiae 1020 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26999&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search OSP 2Q1Q 5356 57298709 CHEMBL328560 DB08329 ZINC00002119 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878567 O=C1NS(=O)(=O)c2ccccc12 InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) CVHZOJJKTDOEJC-UHFFFAOYSA-N 29278 CHEMBL310671::Garantose::SAC::Saccharimide::Saccharin Carbonic anhydrase Saccharomyces cerevisiae 12500 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29278&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search LSA 2Q38,7WJV,5RSP,4RIV,6FJJ,4N1O,3SRK,2Q1B 5143 81054707 32111 CHEMBL310671 5432 C12283 ZINC02560357 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878642 Nc1ccccc1S(N)(=O)=O InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) YAZSBRQTAHVVGE-UHFFFAOYSA-N 10855 2-aminobenzene-1-sulfonamide::CHEMBL6705::US10172837, 2-aminobenzenesulfonamide::aromatic/heteroaromatic sulfonamide 1::orthanilamide 17 Carbonic anhydrase Saccharomyces cerevisiae 82.3 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10855&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 72894 46511428 CHEMBL6705 ZINC00163348 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878643 Nc1ccc(cc1)S(N)(=O)=O InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) FDDDEECHVMSUSB-UHFFFAOYSA-N 10857 4-aminobenzene-1-sulfonamide::CHEMBL21::Sulfanilamide::aromatic sulfonamide compound 5::aromatic/heteroaromatic sulfonamide 2::halogenosulfanilamide deriv. 5a Carbonic anhydrase Saccharomyces cerevisiae 18500 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10857&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search SAN 8BCB,1AJ0,4F93,4F92,4COQ,6RL9 5333 46511429 45373 CHEMBL21 DB00259 C07458 ZINC00002101 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878644 NS(=O)(=O)c1ccc(CCC(O)=O)cc1 InChI=1S/C9H11NO4S/c10-15(13,14)8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5H,3,6H2,(H,11,12)(H2,10,13,14) JUEONDBIBADVGD-UHFFFAOYSA-N 29277 CHEMBL451332::sulfonamide, 3 Carbonic anhydrase Saccharomyces cerevisiae 165 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29277&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search M28 2NN1,2NNO 3161908 81054706 CHEMBL451332 DB08156 ZINC04362893 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 50878645 Cc1ccc(cc1)S(N)(=O)=O InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10) LMYRWZFENFIFIT-UHFFFAOYSA-N 10859 4-methylbenzene-1-sulfonamide::CHEMBL574::aromatic/heteroaromatic sulfonamide 4::hCA inhibitor, 7 Carbonic anhydrase Saccharomyces cerevisiae 16100 ChEMBL 10.1016/j.bmc.2008.12.035 10.7270/Q2FB53WW 19124253 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Balikesir University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10859&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search 4J8 4YXI,6GM9,5RTL,7OYP 6269 46511431 51094 CHEMBL574 C14412 ZINC00388056 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 51085248 CC(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) BZKPWHYZMXOIDC-UHFFFAOYSA-N 10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1 Carbonic anhydrase Saccharomyces cerevisiae 82 ChEMBL 10.1016/j.bmcl.2013.10.037 10.7270/Q2XP76CZ 24210500 Vullo, D; Sai Kumar, RS; Scozzafava, A; Capasso, C; Ferry, JG; Supuran, CT Universit£ degli Studi di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10880&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search AZM 4YGF,3W6H,3CZV,3V2J,3V2M,4G7A,4X5S,6QEB,1YDB,1YDA,1YDD,4LU3,3UCJ,4UOV,2UY4,4K0S,7COJ,4XIW,3HS4,4G0C,1DMY,1AZM,1JD0,1RJ6,1ZSB,2H4N,5JN8,8DYQ,3IAI,6IM3,5NEK,3DC3,2XTK,6MWJ,3ML5,6YMA 1986 46511450 27690 CHEMBL20 DB00819 6792 C06805 ZINC03813042 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3 51054884 CC(=O)Nc1nnc(s1)S(N)(=O)=O InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) BZKPWHYZMXOIDC-UHFFFAOYSA-N 10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1 Carbonic anhydrase Saccharomyces cerevisiae 82 ChEMBL 10.1016/j.bmcl.2013.01.087 10.7270/Q23X8806 23414801 Monti, SM; De Simone, G; Dathan, NA; Ludwig, M; Vullo, D; Scozzafava, A; Capasso, C; Supuran, CT Istituto di Biostrutture e Bioimmagini http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004125&target=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10880&enzyme=Carbonic+anhydrase&column=ki&startPg=0&Increment=50&submit=Search AZM 4YGF,3W6H,3CZV,3V2J,3V2M,4G7A,4X5S,6QEB,1YDB,1YDA,1YDD,4LU3,3UCJ,4UOV,2UY4,4K0S,7COJ,4XIW,3HS4,4G0C,1DMY,1AZM,1JD0,1RJ6,1ZSB,2H4N,5JN8,8DYQ,3IAI,6IM3,5NEK,3DC3,2XTK,6MWJ,3ML5,6YMA 1986 46511450 27690 CHEMBL20 DB00819 6792 C06805 ZINC03813042 1 MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK Carbonic anhydrase CAN_YEAST P53615 D6W1E3