BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50572784 Oc1ccc2cc(C(=O)NCCNC(=O)c3cc4ccc(O)c(O)c4oc3=N)c(=N)oc2c1O InChI=1S/C22H18N4O8/c23-19-11(7-9-1-3-13(27)15(29)17(9)33-19)21(31)25-5-6-26-22(32)12-8-10-2-4-14(28)16(30)18(10)34-20(12)24/h1-4,7-8,23-24,27-30H,5-6H2,(H,25,31)(H,26,32) GNUASFZMLHVMHE-UHFFFAOYSA-N 50316539 CHEMBL1094850::N,N'-(Ethane-1,2-diyl)bis(7,8-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 440 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316539&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237149 104150900 CHEMBL1094850 ZINC49070557 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572785 Oc1cccc2cc(C(=O)NCCCNC(=O)c3cc4cccc(O)c4oc3=N)c(=N)oc12 InChI=1S/C23H20N4O6/c24-20-14(10-12-4-1-6-16(28)18(12)32-20)22(30)26-8-3-9-27-23(31)15-11-13-5-2-7-17(29)19(13)33-21(15)25/h1-2,4-7,10-11,24-25,28-29H,3,8-9H2,(H,26,30)(H,27,31) NKEWQXUSKCGFTE-UHFFFAOYSA-N 50316540 CHEMBL1098763::N,N'-(Propane-1,3-diyl)bis(8-hydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 34800 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316540&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237152 104150901 CHEMBL1098763 ZINC49088220 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572786 Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)cc4oc3=N)c(=N)oc2c1 InChI=1S/C23H20N4O6/c24-20-16(8-12-2-4-14(28)10-18(12)32-20)22(30)26-6-1-7-27-23(31)17-9-13-3-5-15(29)11-19(13)33-21(17)25/h2-5,8-11,24-25,28-29H,1,6-7H2,(H,26,30)(H,27,31) VLAVPACPOLPQDN-UHFFFAOYSA-N 50316541 CHEMBL1096801::N,N'-(Propane-1,3-diyl)bis(7-hydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 16700 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316541&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237153 104150902 CHEMBL1096801 ZINC49124605 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572787 Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)c(O)c4oc3=N)c(=N)oc2c1O InChI=1S/C23H20N4O8/c24-20-12(8-10-2-4-14(28)16(30)18(10)34-20)22(32)26-6-1-7-27-23(33)13-9-11-3-5-15(29)17(31)19(11)35-21(13)25/h2-5,8-9,24-25,28-31H,1,6-7H2,(H,26,32)(H,27,33) WOZKPVAKLXHYED-UHFFFAOYSA-N 50316542 CHEMBL1098764::N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 390 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316542&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237289 104150903 CHEMBL1098764 ZINC49088221 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572788 Oc1cc2cc(C(=O)NCCCNC(=O)c3cc4cc(O)c(O)cc4oc3=N)c(=N)oc2cc1O InChI=1S/C23H20N4O8/c24-20-12(4-10-6-14(28)16(30)8-18(10)34-20)22(32)26-2-1-3-27-23(33)13-5-11-7-15(29)17(31)9-19(11)35-21(13)25/h4-9,24-25,28-31H,1-3H2,(H,26,32)(H,27,33) FKOFIPBOYPUDNV-UHFFFAOYSA-N 50316543 CHEMBL1094197::N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 290 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316543&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237290 104150904 CHEMBL1094197 ZINC49070526 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572789 Oc1ccc2cc(C(=O)NCCNC(=O)c3cc4ccc(O)c(O)c4oc3=N)c(=N)oc2c1O InChI=1S/C22H18N4O8/c23-19-11(7-9-1-3-13(27)15(29)17(9)33-19)21(31)25-5-6-26-22(32)12-8-10-2-4-14(28)16(30)18(10)34-20(12)24/h1-4,7-8,23-24,27-30H,5-6H2,(H,25,31)(H,26,32) GNUASFZMLHVMHE-UHFFFAOYSA-N 50316539 CHEMBL1094850::N,N'-(Ethane-1,2-diyl)bis(7,8-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 1300000 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316539&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237149 104150900 CHEMBL1094850 ZINC49070557 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572790 Oc1cccc2cc(C(=O)NCCCNC(=O)c3cc4cccc(O)c4oc3=N)c(=N)oc12 InChI=1S/C23H20N4O6/c24-20-14(10-12-4-1-6-16(28)18(12)32-20)22(30)26-8-3-9-27-23(31)15-11-13-5-2-7-17(29)19(13)33-21(15)25/h1-2,4-7,10-11,24-25,28-29H,3,8-9H2,(H,26,30)(H,27,31) NKEWQXUSKCGFTE-UHFFFAOYSA-N 50316540 CHEMBL1098763::N,N'-(Propane-1,3-diyl)bis(8-hydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 48200 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316540&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237152 104150901 CHEMBL1098763 ZINC49088220 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572791 Oc1ccc2cc(C(=O)NCCCNC(=O)c3cc4ccc(O)c(O)c4oc3=N)c(=N)oc2c1O InChI=1S/C23H20N4O8/c24-20-12(8-10-2-4-14(28)16(30)18(10)34-20)22(32)26-6-1-7-27-23(33)13-9-11-3-5-15(29)17(31)19(11)35-21(13)25/h2-5,8-9,24-25,28-31H,1,6-7H2,(H,26,32)(H,27,33) WOZKPVAKLXHYED-UHFFFAOYSA-N 50316542 CHEMBL1098764::N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 10700 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316542&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237289 104150903 CHEMBL1098764 ZINC49088221 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50572792 Oc1cc2cc(C(=O)NCCCNC(=O)c3cc4cc(O)c(O)cc4oc3=N)c(=N)oc2cc1O InChI=1S/C23H20N4O8/c24-20-12(4-10-6-14(28)16(30)8-18(10)34-20)22(32)26-2-1-3-27-23(33)13-5-11-7-15(29)17(31)9-19(11)35-21(13)25/h4-9,24-25,28-31H,1-3H2,(H,26,32)(H,27,33) FKOFIPBOYPUDNV-UHFFFAOYSA-N 50316543 CHEMBL1094197::N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2H-chromene-3-carboxamide) Dynamin-2 Homo sapiens 74600 ChEMBL 10.1021/jm100119c 10.7270/Q2PZ5903 20426422 Hill, TA; Mariana, A; Gordon, CP; Odell, LR; Robertson, MJ; McGeachie, AB; Chau, N; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316543&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46237290 104150904 CHEMBL1094197 ZINC49070526 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50913271 OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccccc1O InChI=1S/C22H13ClN2O6/c23-12-6-8-14(22(30)31)16(10-12)24-19(27)11-5-7-13-15(9-11)21(29)25(20(13)28)17-3-1-2-4-18(17)26/h1-10,26H,(H,24,27)(H,30,31) YZCGUQOGRSEYPK-UHFFFAOYSA-N 50318674 4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1Hisoindole-5-carbonyl]amino}benzoic Acid::CHEMBL1083969 Dynamin-2 Homo sapiens 71000 ChEMBL 10.1021/jm100442u 10.7270/Q2PV6MBN 20575553 Odell, LR; Howan, D; Gordon, CP; Robertson, MJ; Chau, N; Mariana, A; Whiting, AE; Abagyan, R; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318674&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46868655 104153035 CHEMBL1083969 ZINC49785765 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50913272 OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(O)cc1 InChI=1S/C22H13ClN2O6/c23-12-2-8-16(22(30)31)18(10-12)24-19(27)11-1-7-15-17(9-11)21(29)25(20(15)28)13-3-5-14(26)6-4-13/h1-10,26H,(H,24,27)(H,30,31) SEVZMDZOXGHKNY-UHFFFAOYSA-N 50318677 4-Chloro-2-{[2-(4-hydroxyphenyl)-1,3-dioxo-2,3-dihydro-1Hisoindole-5-carbonyl]amino}benzoic Acid::CHEMBL1084248 Dynamin-2 Homo sapiens 114000 ChEMBL 10.1021/jm100442u 10.7270/Q2PV6MBN 20575553 Odell, LR; Howan, D; Gordon, CP; Robertson, MJ; Chau, N; Mariana, A; Whiting, AE; Abagyan, R; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318677&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46868657 104153038 CHEMBL1084248 ZINC49036185 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50913273 OC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1cccc(c1)[N+]([O-])=O InChI=1S/C22H12ClN3O7/c23-12-5-7-16(22(30)31)18(9-12)24-19(27)11-4-6-15-17(8-11)21(29)25(20(15)28)13-2-1-3-14(10-13)26(32)33/h1-10H,(H,24,27)(H,30,31) PYVCLVFHOSRDCW-UHFFFAOYSA-N 50318675 4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carbonyl]-amino}-benzoic Acid::CHEMBL1084249 Dynamin-2 Homo sapiens 63000 ChEMBL 10.1021/jm100442u 10.7270/Q2PV6MBN 20575553 Odell, LR; Howan, D; Gordon, CP; Robertson, MJ; Chau, N; Mariana, A; Whiting, AE; Abagyan, R; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318675&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46868787 104153036 CHEMBL1084249 ZINC49785743 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50913274 OCc1ccc(cc1)N1C(=O)c2ccc(cc2C1=O)C(=O)Nc1cc(Cl)ccc1C(O)=O InChI=1S/C23H15ClN2O6/c24-14-4-8-17(23(31)32)19(10-14)25-20(28)13-3-7-16-18(9-13)22(30)26(21(16)29)15-5-1-12(11-27)2-6-15/h1-10,27H,11H2,(H,25,28)(H,31,32) SCXJOBPTOYBNRI-UHFFFAOYSA-N 50318676 4-Chloro-2-{[2-(4-hydroxymethylphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carbonyl]amino}benzoic Acid::CHEMBL1084521 Dynamin-2 Homo sapiens 40000 ChEMBL 10.1021/jm100442u 10.7270/Q2PV6MBN 20575553 Odell, LR; Howan, D; Gordon, CP; Robertson, MJ; Chau, N; Mariana, A; Whiting, AE; Abagyan, R; Daniel, JA; Gorgani, NN; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318676&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 46866791 104153037 CHEMBL1084521 ZINC49111614 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038893 CCCCCCCCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12 InChI=1S/C28H49N3/c1-4-5-6-7-8-9-10-11-12-13-14-17-21-29-24-26-25-31(23-18-22-30(2)3)28-20-16-15-19-27(26)28/h15-16,19-20,25,29H,4-14,17-18,21-24H2,1-3H3 FHXHUSJGTRNFBL-UHFFFAOYSA-N 50423884 CHEMBL2312432 Dynamin-2 Homo sapiens 6800 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423884&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71546961 164152759 CHEMBL2312432 ZINC95593324 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038894 CCCCCCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12 InChI=1S/C26H45N3/c1-4-5-6-7-8-9-10-11-12-15-19-27-22-24-23-29(21-16-20-28(2)3)26-18-14-13-17-25(24)26/h13-14,17-18,23,27H,4-12,15-16,19-22H2,1-3H3 VNQPWAKHRCXOLL-UHFFFAOYSA-N 50423885 CHEMBL2312431 Dynamin-2 Homo sapiens 2800 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423885&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71546960 164152760 CHEMBL2312431 ZINC95596323 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038895 CCCCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12 InChI=1S/C24H41N3/c1-4-5-6-7-8-9-10-13-17-25-20-22-21-27(19-14-18-26(2)3)24-16-12-11-15-23(22)24/h11-12,15-16,21,25H,4-10,13-14,17-20H2,1-3H3 ZXKCYZJGHXORKJ-UHFFFAOYSA-N 50423883 CHEMBL2312430 Dynamin-2 Homo sapiens 1900 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423883&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71546959 164152758 CHEMBL2312430 ZINC95595385 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038896 CCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12 InChI=1S/C22H37N3/c1-4-5-6-7-8-11-15-23-18-20-19-25(17-12-16-24(2)3)22-14-10-9-13-21(20)22/h9-10,13-14,19,23H,4-8,11-12,15-18H2,1-3H3 RDRFARHAZRCRNL-UHFFFAOYSA-N 50423886 CHEMBL2312428 Dynamin-2 Homo sapiens 3500 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423886&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71546812 164152761 CHEMBL2312428 ZINC95598147 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038897 CCCCCCCCNC(=O)C(=C\c1c(C)n(CC(O)CN2CCCC2)c2ccccc12)\C#N InChI=1S/C28H40N4O2/c1-3-4-5-6-7-10-15-30-28(34)23(19-29)18-26-22(2)32(27-14-9-8-13-25(26)27)21-24(33)20-31-16-11-12-17-31/h8-9,13-14,18,24,33H,3-7,10-12,15-17,20-21H2,1-2H3,(H,30,34)/b23-18+ DQHIJWOMMVYHCW-PTGBLXJZSA-N 50423887 CHEMBL2312415 Dynamin-2 Homo sapiens 4500 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423887&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71716723 164152762 CHEMBL2312415 ZINC95595145 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038898 CCCCCCCCNC(=O)C(=C\c1cn(CC(O)CN(C)C)c2ccccc12)\C#N InChI=1S/C25H36N4O2/c1-4-5-6-7-8-11-14-27-25(31)20(16-26)15-21-17-29(19-22(30)18-28(2)3)24-13-10-9-12-23(21)24/h9-10,12-13,15,17,22,30H,4-8,11,14,18-19H2,1-3H3,(H,27,31)/b20-15+ HRFWBDGUUMUKRE-HMMYKYKNSA-N 50423888 CHEMBL2312414 Dynamin-2 Homo sapiens 3500 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423888&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 71546501 164152763 CHEMBL2312414 ZINC95593458 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 51038899 CCCCCCCCNC(=O)C(=C\c1cn(CCCN(C)C)c2ccccc12)\C#N InChI=1S/C25H36N4O/c1-4-5-6-7-8-11-15-27-25(30)21(19-26)18-22-20-29(17-12-16-28(2)3)24-14-10-9-13-23(22)24/h9-10,13-14,18,20H,4-8,11-12,15-17H2,1-3H3,(H,27,30)/b21-18+ MYIMRONQBLZJFI-DYTRJAOYSA-N 50268295 2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-indol-3-yl)-acrylamide::CHEMBL483059 Dynamin-2 Homo sapiens 5000 ChEMBL 10.1021/jm300844m 10.7270/Q2DJ5GZ3 23167654 Gordon, CP; Venn-Brown, B; Robertson, MJ; Young, KA; Chau, N; Mariana, A; Whiting, A; Chircop, M; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268295&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 44157463 104114783 CHEMBL483059 ZINC49872225 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701597 CCCCCCCCCCCCNc1ccnc(NCCN(C)C)n1 InChI=1S/C20H39N5/c1-4-5-6-7-8-9-10-11-12-13-15-21-19-14-16-22-20(24-19)23-17-18-25(2)3/h14,16H,4-13,15,17-18H2,1-3H3,(H2,21,22,23,24) WTFJNTNHMJJVIH-UHFFFAOYSA-N 50233976 CHEMBL4094056 Dynamin-2 Homo sapiens 6100 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233976&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137655412 384584171 CHEMBL4094056 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701600 CN(C)CCNc1cc(C)nc(NC2CCCCC2)n1 InChI=1S/C15H27N5/c1-12-11-14(16-9-10-20(2)3)19-15(17-12)18-13-7-5-4-6-8-13/h11,13H,4-10H2,1-3H3,(H2,16,17,18,19) MMOXJTHENHXEFL-UHFFFAOYSA-N 50233975 CHEMBL4064353 Dynamin-2 Homo sapiens 1800 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233975&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 112910508 384584170 CHEMBL4064353 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701601 CCCCCCCCNc1nc(C)cc(NCCN(C)C)n1 InChI=1S/C17H33N5/c1-5-6-7-8-9-10-11-19-17-20-15(2)14-16(21-17)18-12-13-22(3)4/h14H,5-13H2,1-4H3,(H2,18,19,20,21) LVKPOVWZTWVEDD-UHFFFAOYSA-N 50233977 CHEMBL4086288 Dynamin-2 Homo sapiens 10300 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233977&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137644076 384584172 CHEMBL4086288 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701602 CCCCCCNc1nc(C)cc(NCCN(C)C)n1 InChI=1S/C15H29N5/c1-5-6-7-8-9-17-15-18-13(2)12-14(19-15)16-10-11-20(3)4/h12H,5-11H2,1-4H3,(H2,16,17,18,19) ZWDVYAZGJHLPNO-UHFFFAOYSA-N 50234000 CHEMBL4064810 Dynamin-2 Homo sapiens 47400 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50234000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50234000&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137637881 384584194 CHEMBL4064810 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701603 CCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C15H29N5/c1-5-6-7-8-9-16-14-12-13(2)18-15(19-14)17-10-11-20(3)4/h12H,5-11H2,1-4H3,(H2,16,17,18,19) OVFGOHAKFVQYKZ-UHFFFAOYSA-N 50233981 CHEMBL4060114 Dynamin-2 Homo sapiens 31000 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233981&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137635183 384584176 CHEMBL4060114 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701652 CN(C)CCNc1cc(C)nc(NC2CCCCC2)n1 InChI=1S/C15H27N5/c1-12-11-14(16-9-10-20(2)3)19-15(17-12)18-13-7-5-4-6-8-13/h11,13H,4-10H2,1-3H3,(H2,16,17,18,19) MMOXJTHENHXEFL-UHFFFAOYSA-N 50233975 CHEMBL4064353 Dynamin-2 Homo sapiens 65900 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233975&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 112910508 384584170 CHEMBL4064353 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701678 CCCCCCCCCCNc1ccnc(NCCN(C)C)n1 InChI=1S/C18H35N5/c1-4-5-6-7-8-9-10-11-13-19-17-12-14-20-18(22-17)21-15-16-23(2)3/h12,14H,4-11,13,15-16H2,1-3H3,(H2,19,20,21,22) ZUMMABQMAJHRGO-UHFFFAOYSA-N 50233996 CHEMBL4073407 Dynamin-2 Homo sapiens 3700 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233996&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137640657 384584191 CHEMBL4073407 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701679 CCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C15H29N5/c1-5-6-7-8-9-16-14-12-13(2)18-15(19-14)17-10-11-20(3)4/h12H,5-11H2,1-4H3,(H2,16,17,18,19) OVFGOHAKFVQYKZ-UHFFFAOYSA-N 50233981 CHEMBL4060114 Dynamin-2 Homo sapiens 4000 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233981&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137635183 384584176 CHEMBL4060114 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701680 CCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C19H37N5/c1-5-6-7-8-9-10-11-12-13-20-18-16-17(2)22-19(23-18)21-14-15-24(3)4/h16H,5-15H2,1-4H3,(H2,20,21,22,23) YTWXKAWNLYIAPW-UHFFFAOYSA-N 50233972 CHEMBL4098509 Dynamin-2 Homo sapiens 5100 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233972&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137659724 384584167 CHEMBL4098509 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701683 CCCCCCCCCCCCNc1nc(C)cc(n1)N(C)C InChI=1S/C19H36N4/c1-5-6-7-8-9-10-11-12-13-14-15-20-19-21-17(2)16-18(22-19)23(3)4/h16H,5-15H2,1-4H3,(H,20,21,22) AFQMOKGVILAWQH-UHFFFAOYSA-N 50233983 CHEMBL4073116 Dynamin-2 Homo sapiens 37800 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233983&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137640341 384584178 CHEMBL4073116 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701684 CCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C19H37N5/c1-5-6-7-8-9-10-11-12-13-20-18-16-17(2)22-19(23-18)21-14-15-24(3)4/h16H,5-15H2,1-4H3,(H2,20,21,22,23) YTWXKAWNLYIAPW-UHFFFAOYSA-N 50233972 CHEMBL4098509 Dynamin-2 Homo sapiens 1600 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233972&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137659724 384584167 CHEMBL4098509 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701685 CCCCCCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C23H45N5/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-24-22-20-21(2)26-23(27-22)25-18-19-28(3)4/h20H,5-19H2,1-4H3,(H2,24,25,26,27) XMWGFAZZVIVTAF-UHFFFAOYSA-N 50233961 CHEMBL4071476 Dynamin-2 Homo sapiens 12900 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233961&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137638235 384584156 CHEMBL4071476 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701686 CCCCCCCCCCNc1cc(NCCN(C)C)ncn1 InChI=1S/C18H35N5/c1-4-5-6-7-8-9-10-11-12-19-17-15-18(22-16-21-17)20-13-14-23(2)3/h15-16H,4-14H2,1-3H3,(H2,19,20,21,22) VZIJXHSVBOCFHH-UHFFFAOYSA-N 50233969 CHEMBL4083788 Dynamin-2 Homo sapiens 6000 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233969&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137648429 384584164 CHEMBL4083788 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701687 CCCCCCCCCCCCNc1nc(C)cc(n1)N(C)C InChI=1S/C19H36N4/c1-5-6-7-8-9-10-11-12-13-14-15-20-19-21-17(2)16-18(22-19)23(3)4/h16H,5-15H2,1-4H3,(H,20,21,22) AFQMOKGVILAWQH-UHFFFAOYSA-N 50233983 CHEMBL4073116 Dynamin-2 Homo sapiens 1300 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233983&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137640341 384584178 CHEMBL4073116 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701688 CCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 InChI=1S/C17H33N5/c1-5-6-7-8-9-10-11-18-16-14-15(2)20-17(21-16)19-12-13-22(3)4/h14H,5-13H2,1-4H3,(H2,18,19,20,21) KXSDQUGMAMOWPL-UHFFFAOYSA-N 50233989 CHEMBL4090457 Dynamin-2 Homo sapiens 8700 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233989&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137644023 384584184 CHEMBL4090457 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701691 CCCCCCCCCCCCNc1cc(NCCN(C)C)ncn1 InChI=1S/C20H39N5/c1-4-5-6-7-8-9-10-11-12-13-14-21-19-17-20(24-18-23-19)22-15-16-25(2)3/h17-18H,4-16H2,1-3H3,(H2,21,22,23,24) CVKGWEAWSMDVOS-UHFFFAOYSA-N 50233968 CHEMBL4082410 Dynamin-2 Homo sapiens 8500 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233968&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137648134 384584163 CHEMBL4082410 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701700 CCCCCCCCCCNc1cc(NCCN(C)C)ncn1 InChI=1S/C18H35N5/c1-4-5-6-7-8-9-10-11-12-19-17-15-18(22-16-21-17)20-13-14-23(2)3/h15-16H,4-14H2,1-3H3,(H2,19,20,21,22) VZIJXHSVBOCFHH-UHFFFAOYSA-N 50233969 CHEMBL4083788 Dynamin-2 Homo sapiens 1800 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233969&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137648429 384584164 CHEMBL4083788 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4 50701701 CCCCCCCCCCCCNc1cc(NCCN(C)C)ncn1 InChI=1S/C20H39N5/c1-4-5-6-7-8-9-10-11-12-13-14-21-19-17-20(24-18-23-19)22-15-16-25(2)3/h17-18H,4-16H2,1-3H3,(H2,21,22,23,24) CVKGWEAWSMDVOS-UHFFFAOYSA-N 50233968 CHEMBL4082410 Dynamin-2 Homo sapiens 8300 ChEMBL 10.1021/acs.jmedchem.6b01422 10.7270/Q27M0B6T 27997171 Odell, LR; Abdel-Hamid, MK; Hill, TA; Chau, N; Young, KA; Deane, FM; Sakoff, JA; Andersson, S; Daniel, JA; Robinson, PJ; McCluskey, A The University of Newcastle http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004082&target=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233968&enzyme=Dynamin-2&column=ki&startPg=0&Increment=50&submit=Search 137648134 384584163 CHEMBL4082410 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 2YS1,6S9A Dynamin-2 DYN2_HUMAN P50570 A8K1B6 E7EV30 E9PEQ4 K7ESI9 Q5I0Y0 Q7Z5S3 Q9UPH4