BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51034762 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(C)c(C)c5)CC4)C(=O)O3)c2c1 InChI=1S/C27H31N3O3/c1-18-4-5-20(14-19(18)2)16-29-12-9-21(10-13-29)30-17-26(33-27(30)31)23-8-11-28-25-7-6-22(32-3)15-24(23)25/h4-8,11,14-15,21,26H,9-10,12-13,16-17H2,1-3H3 DBMAUWVASVSMOE-UHFFFAOYSA-N 50423244 CHEMBL397395 C-C chemokine receptor type 8 Homo sapiens 40 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423244&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10003657 164152119 CHEMBL397395 ZINC28893724 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034763 COc1ccc2nccc(C3CN(CCCN(C)Cc4cc5ccccc5[nH]4)C(=O)O3)c2c1 InChI=1S/C26H28N4O3/c1-29(16-19-14-18-6-3-4-7-23(18)28-19)12-5-13-30-17-25(33-26(30)31)21-10-11-27-24-9-8-20(32-2)15-22(21)24/h3-4,6-11,14-15,25,28H,5,12-13,16-17H2,1-2H3 AEAOMQAWGDKZCV-UHFFFAOYSA-N 50423245 CHEMBL240249 C-C chemokine receptor type 8 Homo sapiens 6310 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423245&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439838 164152120 CHEMBL240249 ZINC28892369 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034764 COc1ccc2nccc([C@@H]3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2c1 InChI=1S/C27H28N4O3/c1-33-21-6-7-25-23(15-21)22(8-11-28-25)26-17-31(27(32)34-26)20-9-12-30(13-10-20)16-19-14-18-4-2-3-5-24(18)29-19/h2-8,11,14-15,20,26,29H,9-10,12-13,16-17H2,1H3/t26-/m0/s1 CUWYXEKZVGDQDJ-SANMLTNESA-N 50423246 CHEMBL245568::SB-649701 C-C chemokine receptor type 8 Homo sapiens 501 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423246&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16112836 164152121 CHEMBL245568 ZINC14020727 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034766 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(cc5)C#N)CC4)C(=O)O3)c2c1 InChI=1S/C26H26N4O3/c1-32-21-6-7-24-23(14-21)22(8-11-28-24)25-17-30(26(31)33-25)20-9-12-29(13-10-20)16-19-4-2-18(15-27)3-5-19/h2-8,11,14,20,25H,9-10,12-13,16-17H2,1H3 LZRXJGYRQJPRJM-UHFFFAOYSA-N 50423247 CHEMBL395423 C-C chemokine receptor type 8 Homo sapiens 12589 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423247&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439895 164152122 CHEMBL395423 ZINC28893622 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034767 COc1ccc2nccc(C3CN(C4CCN(CCCc5ccccc5)CC4)C(=O)O3)c2c1 InChI=1S/C27H31N3O3/c1-32-22-9-10-25-24(18-22)23(11-14-28-25)26-19-30(27(31)33-26)21-12-16-29(17-13-21)15-5-8-20-6-3-2-4-7-20/h2-4,6-7,9-11,14,18,21,26H,5,8,12-13,15-17,19H2,1H3 IIODDFVDNAPMCZ-UHFFFAOYSA-N 50423248 CHEMBL247965 C-C chemokine receptor type 8 Homo sapiens 251 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423248&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10433657 164152123 CHEMBL247965 ZINC13976089 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034768 COc1ccc2nccc(C3CN(C4CCN(Cc5cc6ccccc6n5C)CC4)C(=O)O3)c2c1 InChI=1S/C28H30N4O3/c1-30-21(15-19-5-3-4-6-26(19)30)17-31-13-10-20(11-14-31)32-18-27(35-28(32)33)23-9-12-29-25-8-7-22(34-2)16-24(23)25/h3-9,12,15-16,20,27H,10-11,13-14,17-18H2,1-2H3 BMPKSWZOAVAYOT-UHFFFAOYSA-N 50423249 CHEMBL396102 C-C chemokine receptor type 8 Homo sapiens 3162 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423249&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10412437 164152124 CHEMBL396102 ZINC13976088 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034769 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(Br)cc5)CC4)C(=O)O3)c2c1 InChI=1S/C25H26BrN3O3/c1-31-20-6-7-23-22(14-20)21(8-11-27-23)24-16-29(25(30)32-24)19-9-12-28(13-10-19)15-17-2-4-18(26)5-3-17/h2-8,11,14,19,24H,9-10,12-13,15-16H2,1H3 HWCDHOIKZOMDSX-UHFFFAOYSA-N 50423250 CHEMBL395424 C-C chemokine receptor type 8 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423250&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10255258 164152125 CHEMBL395424 ZINC28893653 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034770 COc1ccc2nccc([C@@H]3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2c1 InChI=1S/C27H28N4O3/c1-33-21-6-7-25-23(15-21)22(8-11-28-25)26-17-31(27(32)34-26)20-9-12-30(13-10-20)16-19-14-18-4-2-3-5-24(18)29-19/h2-8,11,14-15,20,26,29H,9-10,12-13,16-17H2,1H3/t26-/m0/s1 CUWYXEKZVGDQDJ-SANMLTNESA-N 50423246 CHEMBL245568::SB-649701 C-C chemokine receptor type 8 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423246&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16112836 164152121 CHEMBL245568 ZINC14020727 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034771 COc1ccc2nccc(C3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2n1 InChI=1S/C26H27N5O3/c1-33-24-7-6-22-25(29-24)20(8-11-27-22)23-16-31(26(32)34-23)19-9-12-30(13-10-19)15-18-14-17-4-2-3-5-21(17)28-18/h2-8,11,14,19,23,28H,9-10,12-13,15-16H2,1H3 SRUSMBPQXNKIIG-UHFFFAOYSA-N 50423251 CHEMBL240461 C-C chemokine receptor type 8 Homo sapiens 32 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423251&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10479253 164152126 CHEMBL240461 ZINC13976090 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034772 COc1ccc(CN2CCC(CC2)N2CC(OC2=O)c2ccnc3ccc(OC)cc23)cc1 InChI=1S/C26H29N3O4/c1-31-20-5-3-18(4-6-20)16-28-13-10-19(11-14-28)29-17-25(33-26(29)30)22-9-12-27-24-8-7-21(32-2)15-23(22)24/h3-9,12,15,19,25H,10-11,13-14,16-17H2,1-2H3 QPSAYNQDLOGFNA-UHFFFAOYSA-N 50423252 CHEMBL248171 C-C chemokine receptor type 8 Homo sapiens 1259 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423252&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439890 164152127 CHEMBL248171 ZINC28893585 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034773 COc1ccc2nccc(C3CN(C4CCN(Cc5ccccc5)CC4)C(=O)O3)c2c1 InChI=1S/C25H27N3O3/c1-30-20-7-8-23-22(15-20)21(9-12-26-23)24-17-28(25(29)31-24)19-10-13-27(14-11-19)16-18-5-3-2-4-6-18/h2-9,12,15,19,24H,10-11,13-14,16-17H2,1H3 LLIDEMDMIYDCFB-UHFFFAOYSA-N 50423253 CHEMBL247964 C-C chemokine receptor type 8 Homo sapiens 12589 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423253&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439886 164152128 CHEMBL247964 ZINC28893534 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034774 COc1ccc2nccc(C3CN(C4CCN(Cc5cc6ccccc6s5)CC4)C(=O)O3)c2c1 InChI=1S/C27H27N3O3S/c1-32-20-6-7-24-23(15-20)22(8-11-28-24)25-17-30(27(31)33-25)19-9-12-29(13-10-19)16-21-14-18-4-2-3-5-26(18)34-21/h2-8,11,14-15,19,25H,9-10,12-13,16-17H2,1H3 OMCPFDYSAAARCE-UHFFFAOYSA-N 50423254 CHEMBL247564 C-C chemokine receptor type 8 Homo sapiens 794 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423254&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10412573 164152129 CHEMBL247564 ZINC28893404 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034776 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc6ccccc6n5)CC4)C(=O)O3)c2c1 InChI=1S/C28H28N4O3/c1-34-22-8-9-26-24(16-22)23(10-13-29-26)27-18-32(28(33)35-27)21-11-14-31(15-12-21)17-20-7-6-19-4-2-3-5-25(19)30-20/h2-10,13,16,21,27H,11-12,14-15,17-18H2,1H3 WRUAHFQBYNBLLM-UHFFFAOYSA-N 50423255 CHEMBL247761 C-C chemokine receptor type 8 Homo sapiens 3162 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423255&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439883 164152130 CHEMBL247761 ZINC28893419 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034777 CCCCCCN1CCC(CC1)N1CC(OC1=O)c1ccnc2ccc(OC)cc12 InChI=1S/C24H33N3O3/c1-3-4-5-6-13-26-14-10-18(11-15-26)27-17-23(30-24(27)28)20-9-12-25-22-8-7-19(29-2)16-21(20)22/h7-9,12,16,18,23H,3-6,10-11,13-15,17H2,1-2H3 PSSYDOSVEYFXCT-UHFFFAOYSA-N 50423256 CHEMBL443315 C-C chemokine receptor type 8 Homo sapiens 501 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423256&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10409369 164152131 CHEMBL443315 ZINC28893501 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034778 COc1ccc2nccc(C3CN(CCCNCc4cc5ccccc5[nH]4)C(=O)O3)c2c1 InChI=1S/C25H26N4O3/c1-31-19-7-8-23-21(14-19)20(9-11-27-23)24-16-29(25(30)32-24)12-4-10-26-15-18-13-17-5-2-3-6-22(17)28-18/h2-3,5-9,11,13-14,24,26,28H,4,10,12,15-16H2,1H3 AQOIKSICNYLNIQ-UHFFFAOYSA-N 50423257 CHEMBL393411 C-C chemokine receptor type 8 Homo sapiens 1585 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423257&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439837 164152132 CHEMBL393411 ZINC28892356 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034779 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(Cl)cc5)CC4)C(=O)O3)c2c1 InChI=1S/C25H26ClN3O3/c1-31-20-6-7-23-22(14-20)21(8-11-27-23)24-16-29(25(30)32-24)19-9-12-28(13-10-19)15-17-2-4-18(26)5-3-17/h2-8,11,14,19,24H,9-10,12-13,15-16H2,1H3 PYKMCNKQAJEMGI-UHFFFAOYSA-N 50423258 CHEMBL396124 C-C chemokine receptor type 8 Homo sapiens 631 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423258&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10343818 164152133 CHEMBL396124 ZINC28893544 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034780 COc1ccc2nccc([C@@H]3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2c1 InChI=1S/C27H28N4O3/c1-33-21-6-7-25-23(15-21)22(8-11-28-25)26-17-31(27(32)34-26)20-9-12-30(13-10-20)16-19-14-18-4-2-3-5-24(18)29-19/h2-8,11,14-15,20,26,29H,9-10,12-13,16-17H2,1H3/t26-/m0/s1 CUWYXEKZVGDQDJ-SANMLTNESA-N 50423246 CHEMBL245568::SB-649701 C-C chemokine receptor type 8 Homo sapiens 25 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423246&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16112836 164152121 CHEMBL245568 ZINC14020727 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034781 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(Cl)c(Cl)c5)CC4)C(=O)O3)c2c1 InChI=1S/C25H25Cl2N3O3/c1-32-18-3-5-23-20(13-18)19(6-9-28-23)24-15-30(25(31)33-24)17-7-10-29(11-8-17)14-16-2-4-21(26)22(27)12-16/h2-6,9,12-13,17,24H,7-8,10-11,14-15H2,1H3 UPBONKUQKKQLND-UHFFFAOYSA-N 50423259 CHEMBL395211 C-C chemokine receptor type 8 Homo sapiens 126 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423259&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10480554 164152134 CHEMBL395211 ZINC28893738 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034782 COc1ccc2nccc(C3CN(C4CCN(Cc5cc6ccccc6o5)CC4)C(=O)O3)c2c1 InChI=1S/C27H27N3O4/c1-32-20-6-7-24-23(15-20)22(8-11-28-24)26-17-30(27(31)34-26)19-9-12-29(13-10-19)16-21-14-18-4-2-3-5-25(18)33-21/h2-8,11,14-15,19,26H,9-10,12-13,16-17H2,1H3 NEBVJGRFYWCFPT-UHFFFAOYSA-N 50423260 CHEMBL247563 C-C chemokine receptor type 8 Homo sapiens 1259 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423260&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439881 164152135 CHEMBL247563 ZINC28893393 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034783 COc1ccc2nccc(C3CN(C4CCN(Cc5cccc(Cl)c5)CC4)C(=O)O3)c2c1 InChI=1S/C25H26ClN3O3/c1-31-20-5-6-23-22(14-20)21(7-10-27-23)24-16-29(25(30)32-24)19-8-11-28(12-9-19)15-17-3-2-4-18(26)13-17/h2-7,10,13-14,19,24H,8-9,11-12,15-16H2,1H3 ZBEZRCJKLIAIJX-UHFFFAOYSA-N 50423261 CHEMBL248169 C-C chemokine receptor type 8 Homo sapiens 6310 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423261&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439887 164152136 CHEMBL248169 ZINC28893557 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034784 O=C1OC(CN1C1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccnc2ccccc12 InChI=1S/C26H26N4O2/c31-26-30(17-25(32-26)22-9-12-27-24-8-4-2-6-21(22)24)20-10-13-29(14-11-20)16-19-15-18-5-1-3-7-23(18)28-19/h1-9,12,15,20,25,28H,10-11,13-14,16-17H2 CPIBHOSTAJXYKE-UHFFFAOYSA-N 50423262 CHEMBL240462 C-C chemokine receptor type 8 Homo sapiens 1000 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423262&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439843 164152137 CHEMBL240462 ZINC28892465 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034785 COc1ccc2nccc(C3CN(C4CCN(Cc5ccc6ccccc6c5)CC4)C(=O)O3)c2c1 InChI=1S/C29H29N3O3/c1-34-24-8-9-27-26(17-24)25(10-13-30-27)28-19-32(29(33)35-28)23-11-14-31(15-12-23)18-20-6-7-21-4-2-3-5-22(21)16-20/h2-10,13,16-17,23,28H,11-12,14-15,18-19H2,1H3 CXPWIZLGIZBSFJ-UHFFFAOYSA-N 50423263 CHEMBL247762 C-C chemokine receptor type 8 Homo sapiens 1259 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423263&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10004785 164152138 CHEMBL247762 ZINC28893429 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034786 COc1ccc2nccc(C3CN(C4CCN(CC5CCCCC5)CC4)C(=O)O3)c2c1 InChI=1S/C25H33N3O3/c1-30-20-7-8-23-22(15-20)21(9-12-26-23)24-17-28(25(29)31-24)19-10-13-27(14-11-19)16-18-5-3-2-4-6-18/h7-9,12,15,18-19,24H,2-6,10-11,13-14,16-17H2,1H3 QYDKOWROHHZSPY-UHFFFAOYSA-N 50423264 CHEMBL247963 C-C chemokine receptor type 8 Homo sapiens 7943 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423264&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439885 164152139 CHEMBL247963 ZINC28893523 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034787 COc1ccc2nccc([C@@H]3CN(C4CCN(Cc5cc6ccccc6[nH]5)CC4)C(=O)O3)c2c1 InChI=1S/C27H28N4O3/c1-33-21-6-7-25-23(15-21)22(8-11-28-25)26-17-31(27(32)34-26)20-9-12-30(13-10-20)16-19-14-18-4-2-3-5-24(18)29-19/h2-8,11,14-15,20,26,29H,9-10,12-13,16-17H2,1H3/t26-/m0/s1 CUWYXEKZVGDQDJ-SANMLTNESA-N 50423246 CHEMBL245568::SB-649701 C-C chemokine receptor type 8 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423246&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16112836 164152121 CHEMBL245568 ZINC14020727 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51034788 COc1ccc2nccc(C3CN(C4CCN(CC4)C(=O)c4ccc(Cl)c(Cl)c4)C(=O)O3)c2c1 InChI=1S/C25H23Cl2N3O4/c1-33-17-3-5-22-19(13-17)18(6-9-28-22)23-14-30(25(32)34-23)16-7-10-29(11-8-16)24(31)15-2-4-20(26)21(27)12-15/h2-6,9,12-13,16,23H,7-8,10-11,14H2,1H3 XINSEQKDTJNMSQ-UHFFFAOYSA-N 50423265 CHEMBL430012 C-C chemokine receptor type 8 Homo sapiens 6310 ChEMBL 10.1016/j.bmcl.2006.12.076 10.7270/Q2668FG7 17267215 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423265&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44439909 164152140 CHEMBL430012 ZINC28893759 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035863 COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2cc[n+]([O-])cc2)c1 InChI=1S/C29H33N3O4/c1-35-26-7-2-3-8-27(26)36-25-6-4-5-23(21-25)22-30-17-11-29(12-18-30)13-19-31(20-14-29)28(33)24-9-15-32(34)16-10-24/h2-10,15-16,21H,11-14,17-20,22H2,1H3 UEDWHHXUOBFTMS-UHFFFAOYSA-N 50414969 CHEMBL272022 C-C chemokine receptor type 8 Homo sapiens 33 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414969&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11951000 163363993 CHEMBL272022 ZINC29133063 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035864 COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccc(Cl)cc2)c1 InChI=1S/C30H33ClN2O3/c1-35-27-7-2-3-8-28(27)36-26-6-4-5-23(21-26)22-32-17-13-30(14-18-32)15-19-33(20-16-30)29(34)24-9-11-25(31)12-10-24/h2-12,21H,13-20,22H2,1H3 WUCNLBAXCJABQR-UHFFFAOYSA-N 50423492 CHEMBL409648 C-C chemokine receptor type 8 Homo sapiens 12 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423492&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457009 164152367 CHEMBL409648 ZINC29133367 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035865 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C29H33N3O3/c1-34-26-8-4-5-9-27(26)35-25-7-3-2-6-24(25)22-31-18-12-29(13-19-31)14-20-32(21-15-29)28(33)23-10-16-30-17-11-23/h2-11,16-17H,12-15,18-22H2,1H3 WWTXVMIWFBVHQA-UHFFFAOYSA-N 50414964 CHEMBL271128 C-C chemokine receptor type 8 Homo sapiens 12 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414964&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457090 163363988 CHEMBL271128 ZINC29133668 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035866 COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2cccc[n+]2[O-])c1 InChI=1S/C29H33N3O4/c1-35-26-10-2-3-11-27(26)36-24-8-6-7-23(21-24)22-30-17-12-29(13-18-30)14-19-31(20-15-29)28(33)25-9-4-5-16-32(25)34/h2-11,16,21H,12-15,17-20,22H2,1H3 SELXSHINISBLTM-UHFFFAOYSA-N 50423493 CHEMBL411651 C-C chemokine receptor type 8 Homo sapiens 27 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423493&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11842667 164152368 CHEMBL411651 ZINC29133055 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035867 Clc1ccc(cc1)C(=O)N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1 InChI=1S/C29H31ClN2O2/c30-25-12-10-23(11-13-25)28(33)32-20-16-29(17-21-32)14-18-31(19-15-29)22-24-6-4-5-9-27(24)34-26-7-2-1-3-8-26/h1-13H,14-22H2 CSMSBZWRUZAKQB-UHFFFAOYSA-N 50414958 CHEMBL259243 C-C chemokine receptor type 8 Homo sapiens 81 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414958&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11273324 163363982 CHEMBL259243 ZINC13981733 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035868 [O-][n+]1ccc(cc1)C(=O)N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1 InChI=1S/C28H31N3O3/c32-27(24-9-15-31(33)16-10-24)30-19-13-28(14-20-30)11-17-29(18-12-28)22-23-5-4-8-26(21-23)34-25-6-2-1-3-7-25/h1-10,15-16,21H,11-14,17-20,22H2 UVYDBEOMZNPYJF-UHFFFAOYSA-N 50423494 CHEMBL409849 C-C chemokine receptor type 8 Homo sapiens 166 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423494&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11950826 164152369 CHEMBL409849 ZINC29133060 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035869 O=C(N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1)c1ccncn1 InChI=1S/C27H30N4O2/c32-26(25-9-14-28-21-29-25)31-17-12-27(13-18-31)10-15-30(16-11-27)20-22-5-4-8-24(19-22)33-23-6-2-1-3-7-23/h1-9,14,19,21H,10-13,15-18,20H2 GDZWYFZOGVMUEB-UHFFFAOYSA-N 50414968 CHEMBL410885 C-C chemokine receptor type 8 Homo sapiens 28 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414968&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44456948 163363992 CHEMBL410885 ZINC29133131 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035870 O=C(N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1)c1ccncc1 InChI=1S/C28H31N3O2/c32-27(24-9-15-29-16-10-24)31-19-13-28(14-20-31)11-17-30(18-12-28)22-23-5-4-8-26(21-23)33-25-6-2-1-3-7-25/h1-10,15-16,21H,11-14,17-20,22H2 KHWFDRKDQCSBEW-UHFFFAOYSA-N 50414967 CHEMBL271801 C-C chemokine receptor type 8 Homo sapiens 18 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414967&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44456993 163363991 CHEMBL271801 ZINC29133289 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035871 Clc1ccc(cc1)C(=O)N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1 InChI=1S/C29H31ClN2O2/c30-25-11-9-24(10-12-25)28(33)32-19-15-29(16-20-32)13-17-31(18-14-29)22-23-5-4-8-27(21-23)34-26-6-2-1-3-7-26/h1-12,21H,13-20,22H2 RGZNEXHZUKHBNS-UHFFFAOYSA-N 50414957 CHEMBL429436 C-C chemokine receptor type 8 Homo sapiens 19 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414957&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457046 163363981 CHEMBL429436 ZINC29133518 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035872 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1cccc[n+]1[O-] InChI=1S/C29H33N3O4/c1-35-26-11-4-5-12-27(26)36-25-10-3-2-8-23(25)22-30-18-13-29(14-19-30)15-20-31(21-16-29)28(33)24-9-6-7-17-32(24)34/h2-12,17H,13-16,18-22H2,1H3 BEWXCKHNNXXEFC-UHFFFAOYSA-N 50423495 CHEMBL270969 C-C chemokine receptor type 8 Homo sapiens 79 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423495&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11950827 164152370 CHEMBL270969 ZINC29133609 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035873 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1cc[n+]([O-])cc1 InChI=1S/C29H33N3O4/c1-35-26-8-4-5-9-27(26)36-25-7-3-2-6-24(25)22-30-18-12-29(13-19-30)14-20-31(21-15-29)28(33)23-10-16-32(34)17-11-23/h2-11,16-17H,12-15,18-22H2,1H3 DVQXAHGZSWJSQT-UHFFFAOYSA-N 50414965 CHEMBL270971 C-C chemokine receptor type 8 Homo sapiens 115 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414965&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11950828 163363989 CHEMBL270971 ZINC29133611 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035874 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccccn1 InChI=1S/C29H33N3O3/c1-34-26-11-4-5-12-27(26)35-25-10-3-2-8-23(25)22-31-18-13-29(14-19-31)15-20-32(21-16-29)28(33)24-9-6-7-17-30-24/h2-12,17H,13-16,18-22H2,1H3 ALWYLDGQXRIBHM-UHFFFAOYSA-N 50411749 CHEMBL271127 C-C chemokine receptor type 8 Homo sapiens 16 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411749&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457089 163360773 CHEMBL271127 ZINC29133666 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035875 O=C(N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1)c1ccncc1 InChI=1S/C28H31N3O2/c32-27(23-10-16-29-17-11-23)31-20-14-28(15-21-31)12-18-30(19-13-28)22-24-6-4-5-9-26(24)33-25-7-2-1-3-8-25/h1-11,16-17H,12-15,18-22H2 IRDUJBOZWQOVPG-UHFFFAOYSA-N 50423496 CHEMBL271768 C-C chemokine receptor type 8 Homo sapiens 33 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50423496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50423496&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457093 164152371 CHEMBL271768 ZINC29133670 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51035876 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc(Cl)cc1 InChI=1S/C30H33ClN2O3/c1-35-27-8-4-5-9-28(27)36-26-7-3-2-6-24(26)22-32-18-14-30(15-19-32)16-20-33(21-17-30)29(34)23-10-12-25(31)13-11-23/h2-13H,14-22H2,1H3 FVIRTVGXWNRAMY-UHFFFAOYSA-N 50414959 CHEMBL409224 C-C chemokine receptor type 8 Homo sapiens 35 ChEMBL 10.1021/jm070543k 10.7270/Q2C24XMG 18257512 Shamovsky, I; Connolly, S; David, L; Ivanova, S; Norden, B; Springthorpe, B; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414959&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457105 163363983 CHEMBL409224 ZINC29133717 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344311 CCOC(=O)C1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C21H25NO3/c1-2-24-21(23)18-11-13-22(14-12-18)16-17-7-6-10-20(15-17)25-19-8-4-3-5-9-19/h3-10,15,18H,2,11-14,16H2,1H3 TVFMBJYYWFCDRX-UHFFFAOYSA-N 50185903 1-(3-phenoxy-benzyl)-piperidine-4-carboxylic acid ethyl ester::CHEMBL205808 C-C chemokine receptor type 8 Homo sapiens 2600 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185903&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 792361 104069974 CHEMBL205808 ZINC04978046 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344314 CCN1CCC(CC1)(C(=O)NC1(CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)C(O)=O)c1ccccc1 InChI=1S/C33H38ClN3O4/c1-2-36-19-15-32(16-20-36,26-10-4-3-5-11-26)30(38)35-33(31(39)40)17-21-37(22-18-33)24-25-9-8-12-27(23-25)41-29-14-7-6-13-28(29)34/h3-14,23H,2,15-22,24H2,1H3,(H,35,38)(H,39,40) YGYLUOKAHBFLCH-UHFFFAOYSA-N 50185906 1-[3-(2-chlorophenoxy)benzyl]-4-{[(1-ethyl-4-phenylpiperidin-4-yl)carbonyl]amino} piperidine-4-carboxylic acid::CHEMBL436753 C-C chemokine receptor type 8 Homo sapiens 23 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185906&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11563243 104069977 CHEMBL436753 ZINC25422036 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344315 Clc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)C2(CCNC2)c2ccccc2)c1 InChI=1S/C29H32ClN3O2/c30-26-11-4-5-12-27(26)35-25-10-6-7-22(19-25)20-33-17-13-24(14-18-33)32-28(34)29(15-16-31-21-29)23-8-2-1-3-9-23/h1-12,19,24,31H,13-18,20-21H2,(H,32,34) XZSLPXJGQLDVET-UHFFFAOYSA-N 50185904 (+/-) 3-phenyl-pyrrolidine-3-carboxylic acid {1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL381619 C-C chemokine receptor type 8 Homo sapiens 27 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185904&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11584004 104069975 CHEMBL381619 ZINC13686247 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344317 COc1ccccc1Oc1cccc(CN2CCC(CC2)(NC(=O)C2(CCNCC2)c2ccccc2)C(O)=O)c1 InChI=1S/C32H37N3O5/c1-39-27-12-5-6-13-28(27)40-26-11-7-8-24(22-26)23-35-20-16-32(17-21-35,30(37)38)34-29(36)31(14-18-33-19-15-31)25-9-3-2-4-10-25/h2-13,22,33H,14-21,23H2,1H3,(H,34,36)(H,37,38) TUFFUEHRXNGQLP-UHFFFAOYSA-N 50185902 1-[3-(2-methoxy-phenoxy)-benzyl]-4-[(4-phenyl-piperidine-4-carbonyl)-amino]-piperidine-4-carboxylic acid::CHEMBL379834 C-C chemokine receptor type 8 Homo sapiens 60 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185902&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11706579 104069973 CHEMBL379834 ZINC36184916 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344318 CC(C)(N1CCC(C1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O InChI=1S/C33H38ClN3O4/c1-32(2,31(39)40)37-20-17-33(23-37,25-10-4-3-5-11-25)30(38)35-26-15-18-36(19-16-26)22-24-9-8-12-27(21-24)41-29-14-7-6-13-28(29)34/h3-14,21,26H,15-20,22-23H2,1-2H3,(H,35,38)(H,39,40) QIDWKMNIWOOQON-UHFFFAOYSA-N 50185909 2-(3-((1-(3-(2-chlorophenoxy)benzyl)piperidin-4-yl)carbamoyl)-3-phenylpyrrolidin-1-yl)-2-methylpropanoic acid::CHEMBL205993 C-C chemokine receptor type 8 Homo sapiens 6 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185909&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11541506 104069980 CHEMBL205993 ZINC36184915 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344319 CCN1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3OC)c2)CC1)c1ccccc1 InChI=1S/C33H41N3O3/c1-3-35-22-18-33(19-23-35,27-11-5-4-6-12-27)32(37)34-28-16-20-36(21-17-28)25-26-10-9-13-29(24-26)39-31-15-8-7-14-30(31)38-2/h4-15,24,28H,3,16-23,25H2,1-2H3,(H,34,37) OIZAFWVARZBXFK-UHFFFAOYSA-N 50185908 1-ethyl-4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL209350 C-C chemokine receptor type 8 Homo sapiens 56 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185908&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11519336 104069979 CHEMBL209350 ZINC13686231 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344321 COc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)c1 InChI=1S/C27H30N2O3/c1-31-25-12-5-6-13-26(25)32-24-11-7-10-22(18-24)20-29-16-14-23(15-17-29)28-27(30)19-21-8-3-2-4-9-21/h2-13,18,23H,14-17,19-20H2,1H3,(H,28,30) BABAHNGGVSLMEF-UHFFFAOYSA-N 50185907 CHEMBL210322::N-{1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-2-phenyl-acetamide C-C chemokine receptor type 8 Homo sapiens 55 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185907&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11539239 104069978 CHEMBL210322 ZINC13686221 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344322 CC(C)(N1CCC(C1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O InChI=1S/C33H38ClN3O4/c1-32(2,31(39)40)37-20-17-33(23-37,25-10-4-3-5-11-25)30(38)35-26-15-18-36(19-16-26)22-24-9-8-12-27(21-24)41-29-14-7-6-13-28(29)34/h3-14,21,26H,15-20,22-23H2,1-2H3,(H,35,38)(H,39,40) QIDWKMNIWOOQON-UHFFFAOYSA-N 50185909 2-(3-((1-(3-(2-chlorophenoxy)benzyl)piperidin-4-yl)carbamoyl)-3-phenylpyrrolidin-1-yl)-2-methylpropanoic acid::CHEMBL205993 C-C chemokine receptor type 8 Homo sapiens 1 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185909&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11541506 104069980 CHEMBL205993 ZINC36184915 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344323 CCN1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1 InChI=1S/C32H38ClN3O2/c1-2-35-21-17-32(18-22-35,26-10-4-3-5-11-26)31(37)34-27-15-19-36(20-16-27)24-25-9-8-12-28(23-25)38-30-14-7-6-13-29(30)33/h3-14,23,27H,2,15-22,24H2,1H3,(H,34,37) VACZJUIZGZSWET-UHFFFAOYSA-N 50185910 1-ethyl-4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL204419 C-C chemokine receptor type 8 Homo sapiens 43 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185910&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11526626 104069981 CHEMBL204419 ZINC13686236 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344324 CC(C)(N1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O InChI=1S/C34H40ClN3O4/c1-33(2,32(40)41)38-21-17-34(18-22-38,26-10-4-3-5-11-26)31(39)36-27-15-19-37(20-16-27)24-25-9-8-12-28(23-25)42-30-14-7-6-13-29(30)35/h3-14,23,27H,15-22,24H2,1-2H3,(H,36,39)(H,40,41) TXEFMFGXKKPZEW-UHFFFAOYSA-N 50185912 2-(4-{1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-ylcarbamoyl}-4-phenyl-piperidin-1-yl)-2-methyl-propionic acid::CHEMBL380492 C-C chemokine receptor type 8 Homo sapiens 4 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185912&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11685733 104069983 CHEMBL380492 ZINC25422030 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344326 O=C(Cc1ccccc1)NC1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C26H28N2O2/c29-26(19-21-8-3-1-4-9-21)27-23-14-16-28(17-15-23)20-22-10-7-13-25(18-22)30-24-11-5-2-6-12-24/h1-13,18,23H,14-17,19-20H2,(H,27,29) NUWCFGTWEDHTKQ-UHFFFAOYSA-N 50185911 CHEMBL205692::N-[1-(3-phenoxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide C-C chemokine receptor type 8 Homo sapiens 1400 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185911&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11502217 104069982 CHEMBL205692 ZINC13686216 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344331 OC(=O)C1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C19H21NO3/c21-19(22)16-9-11-20(12-10-16)14-15-5-4-8-18(13-15)23-17-6-2-1-3-7-17/h1-8,13,16H,9-12,14H2,(H,21,22) VHHPNELKVATLRV-UHFFFAOYSA-N 50185914 1-(3-phenoxybenzyl)piperidine-4-carboxylic acid::CHEMBL377931 C-C chemokine receptor type 8 Homo sapiens >30000 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185914&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 3989497 104069985 CHEMBL377931 ZINC03747642 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344332 CC(C)(N1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O InChI=1S/C34H40ClN3O4/c1-33(2,32(40)41)38-21-17-34(18-22-38,26-10-4-3-5-11-26)31(39)36-27-15-19-37(20-16-27)24-25-9-8-12-28(23-25)42-30-14-7-6-13-29(30)35/h3-14,23,27H,15-22,24H2,1-2H3,(H,36,39)(H,40,41) TXEFMFGXKKPZEW-UHFFFAOYSA-N 50185912 2-(4-{1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-ylcarbamoyl}-4-phenyl-piperidin-1-yl)-2-methyl-propionic acid::CHEMBL380492 C-C chemokine receptor type 8 Homo sapiens 9 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185912&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11685733 104069983 CHEMBL380492 ZINC25422030 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344336 CCNC(=O)C1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C21H26N2O2/c1-2-22-21(24)18-11-13-23(14-12-18)16-17-7-6-10-20(15-17)25-19-8-4-3-5-9-19/h3-10,15,18H,2,11-14,16H2,1H3,(H,22,24) YYYKGWKTHWSOEJ-UHFFFAOYSA-N 50185916 1-(3-phenoxy-benzyl)-piperidine-4-carboxylic acid ethylamide::CHEMBL205304 C-C chemokine receptor type 8 Homo sapiens 9100 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185916&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11530171 104069987 CHEMBL205304 ZINC13686206 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344337 COc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)C2(CCNCC2)c2ccccc2)c1 InChI=1S/C31H37N3O3/c1-36-28-12-5-6-13-29(28)37-27-11-7-8-24(22-27)23-34-20-14-26(15-21-34)33-30(35)31(16-18-32-19-17-31)25-9-3-2-4-10-25/h2-13,22,26,32H,14-21,23H2,1H3,(H,33,35) DWMQJCAMZAGHHZ-UHFFFAOYSA-N 50185905 4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL205447 C-C chemokine receptor type 8 Homo sapiens 62 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185905&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11533398 104069976 CHEMBL205447 ZINC13686227 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344338 CCN1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1 InChI=1S/C32H38ClN3O2/c1-2-35-21-17-32(18-22-35,26-10-4-3-5-11-26)31(37)34-27-15-19-36(20-16-27)24-25-9-8-12-28(23-25)38-30-14-7-6-13-29(30)33/h3-14,23,27H,2,15-22,24H2,1H3,(H,34,37) VACZJUIZGZSWET-UHFFFAOYSA-N 50185910 1-ethyl-4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL204419 C-C chemokine receptor type 8 Homo sapiens 15 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185910&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11526626 104069981 CHEMBL204419 ZINC13686236 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344339 COc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)c1 InChI=1S/C27H30N2O3/c1-31-25-12-5-6-13-26(25)32-24-11-7-10-22(18-24)20-29-16-14-23(15-17-29)28-27(30)19-21-8-3-2-4-9-21/h2-13,18,23H,14-17,19-20H2,1H3,(H,28,30) BABAHNGGVSLMEF-UHFFFAOYSA-N 50185907 CHEMBL210322::N-{1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-2-phenyl-acetamide C-C chemokine receptor type 8 Homo sapiens 250 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185907&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11539239 104069978 CHEMBL210322 ZINC13686221 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344340 COc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)C2(CCCCC2)c2ccc(Cl)cc2)c1 InChI=1S/C32H37ClN2O3/c1-37-29-10-3-4-11-30(29)38-28-9-7-8-24(22-28)23-35-20-16-27(17-21-35)34-31(36)32(18-5-2-6-19-32)25-12-14-26(33)15-13-25/h3-4,7-15,22,27H,2,5-6,16-21,23H2,1H3,(H,34,36) HEILLZBUQBOKMO-UHFFFAOYSA-N 50185915 1-(4-chloro-phenyl)-cyclohexanecarboxylic acid {1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL205457 C-C chemokine receptor type 8 Homo sapiens 250 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185915&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11541073 104069986 CHEMBL205457 ZINC13686223 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344341 COc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)C2(CCNCC2)c2ccccc2)c1 InChI=1S/C31H37N3O3/c1-36-28-12-5-6-13-29(28)37-27-11-7-8-24(22-27)23-34-20-14-26(15-21-34)33-30(35)31(16-18-32-19-17-31)25-9-3-2-4-10-25/h2-13,22,26,32H,14-21,23H2,1H3,(H,33,35) DWMQJCAMZAGHHZ-UHFFFAOYSA-N 50185905 4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL205447 C-C chemokine receptor type 8 Homo sapiens 11 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185905&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11533398 104069976 CHEMBL205447 ZINC13686227 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344342 CCN1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3OC)c2)CC1)c1ccccc1 InChI=1S/C33H41N3O3/c1-3-35-22-18-33(19-23-35,27-11-5-4-6-12-27)32(37)34-28-16-20-36(21-17-28)25-26-10-9-13-29(24-26)39-31-15-8-7-14-30(31)38-2/h4-15,24,28H,3,16-23,25H2,1-2H3,(H,34,37) OIZAFWVARZBXFK-UHFFFAOYSA-N 50185908 1-ethyl-4-phenyl-piperidine-4-carboxylic acid {1-[3-(2-methoxy-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL209350 C-C chemokine receptor type 8 Homo sapiens 11 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185908&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11519336 104069979 CHEMBL209350 ZINC13686231 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344349 CCC(=O)NC1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C21H26N2O2/c1-2-21(24)22-18-11-13-23(14-12-18)16-17-7-6-10-20(15-17)25-19-8-4-3-5-9-19/h3-10,15,18H,2,11-14,16H2,1H3,(H,22,24) IKJHFSQVBUKKHY-UHFFFAOYSA-N 50185913 CHEMBL381354::N-[1-(3-phenoxy-benzyl)-piperidin-4-yl]-propionamide C-C chemokine receptor type 8 Homo sapiens 9200 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185913&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11681610 104069984 CHEMBL381354 ZINC13686211 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50344350 Clc1ccccc1Oc1cccc(CN2CCC(CC2)NC(=O)C2(CCNC2)c2ccccc2)c1 InChI=1S/C29H32ClN3O2/c30-26-11-4-5-12-27(26)35-25-10-6-7-22(19-25)20-33-17-13-24(14-18-33)32-28(34)29(15-16-31-21-29)23-8-2-1-3-9-23/h1-12,19,24,31H,13-18,20-21H2,(H,32,34) XZSLPXJGQLDVET-UHFFFAOYSA-N 50185904 (+/-) 3-phenyl-pyrrolidine-3-carboxylic acid {1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-yl}-amide::CHEMBL381619 C-C chemokine receptor type 8 Homo sapiens 22 ChEMBL 10.1021/jm050965z 10.7270/Q2GH9HJX 16640325 Ghosh, S; Elder, A; Guo, J; Mani, U; Patane, M; Carson, K; Ye, Q; Bennett, R; Chi, S; Jenkins, T; Guan, B; Kolbeck, R; Smith, S; Zhang, C; LaRosa, G; Jaffee, B; Yang, H; Eddy, P; Lu, C; Uttamsingh, V; Horlick, R; Harriman, G; Flynn, D Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185904&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11584004 104069975 CHEMBL381619 ZINC13686247 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50346485 FC(F)(F)c1cc(CNC(=O)[C@@H](NCCN2CCCCC2)c2ccsc2)cc(c1)C(F)(F)F InChI=1S/C22H25F6N3OS/c23-21(24,25)17-10-15(11-18(12-17)22(26,27)28)13-30-20(32)19(16-4-9-33-14-16)29-5-8-31-6-2-1-3-7-31/h4,9-12,14,19,29H,1-3,5-8,13H2,(H,30,32)/t19-/m0/s1 NLWNSKCTNYPJQF-IBGZPJMESA-N 50187033 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piperidin-1-yl)ethylamino)-2-(thiophen-3-yl)acetamide::CHEMBL211775 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1016/j.bmcl.2006.04.045 10.7270/Q2N01645 16698264 Yang, L; Zhou, C; Guo, L; Morriello, G; Butora, G; Pasternak, A; Parsons, WH; Mills, SG; MacCoss, M; Vicario, PP; Zweerink, H; Ayala, JM; Goyal, S; Hanlon, WA; Cascieri, MA; Springer, MS Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187033&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10323427 104071072 CHEMBL211775 ZINC34804147 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373132 CCCCCc1ccc(cc1)C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCC InChI=1S/C31H39N3O4S/c1-3-5-6-10-23-13-15-24(16-14-23)31(36)32-28-17-18-29(27-12-8-7-11-26(27)28)39(37,38)33-25-19-21-34(22-20-25)30(35)9-4-2/h7-8,11-18,25,33H,3-6,9-10,19-22H2,1-2H3,(H,32,36) ZGKUKXPHLCLKQW-UHFFFAOYSA-N 50203830 CHEMBL219431::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-4-pentylbenzamide C-C chemokine receptor type 8 Homo sapiens 36.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203830&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105775 104082788 CHEMBL219431 ZINC38151318 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373133 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C27H31N3O4S/c1-3-8-26(31)30-17-15-20(16-18-30)29-35(33,34)25-14-13-24(22-11-6-7-12-23(22)25)28-27(32)21-10-5-4-9-19(21)2/h4-7,9-14,20,29H,3,8,15-18H2,1-2H3,(H,28,32) LOBUISIPHBRTPI-UHFFFAOYSA-N 50203831 CHEMBL374939::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 0.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203831&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10391001 104082789 CHEMBL374939 ZINC36184921 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373134 CNC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C25H28N4O4S/c1-17-7-3-4-8-19(17)24(30)27-22-11-12-23(21-10-6-5-9-20(21)22)34(32,33)28-18-13-15-29(16-14-18)25(31)26-2/h3-12,18,28H,13-16H2,1-2H3,(H,26,31)(H,27,30) SYWOHCXHUUSVLW-UHFFFAOYSA-N 50203832 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid methylamide::CHEMBL221865 C-C chemokine receptor type 8 Homo sapiens 0.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203832&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11754900 104082790 CHEMBL221865 ZINC36184920 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373135 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CCOCC2)c2ccccc12 InChI=1S/C25H33N3O5S/c1-2-5-24(29)28-14-10-19(11-15-28)27-34(31,32)23-9-8-22(20-6-3-4-7-21(20)23)26-25(30)18-12-16-33-17-13-18/h3-4,6-9,18-19,27H,2,5,10-17H2,1H3,(H,26,30) UOMKWROAWZKZLC-UHFFFAOYSA-N 50203833 CHEMBL218209::tetrahydro-pyran-4-carboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide C-C chemokine receptor type 8 Homo sapiens 205.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203833&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105855 104082791 CHEMBL218209 ZINC35242632 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373136 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)[C@@H]1CCCN1 InChI=1S/C28H32N4O4S/c1-19-7-2-3-8-21(19)27(33)30-24-12-13-26(23-10-5-4-9-22(23)24)37(35,36)31-20-14-17-32(18-15-20)28(34)25-11-6-16-29-25/h2-5,7-10,12-13,20,25,29,31H,6,11,14-18H2,1H3,(H,30,33)/t25-/m0/s1 GKEJTJFRAKDFAV-VWLOTQADSA-N 50203834 2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]piperidin-4-yl}amino)sulfonyl]-1-naphthyl}benzamide::2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]piperidin-4-yl}amino)sulfonyl]-1-naphthyl}benzamide)::CHEMBL386308 C-C chemokine receptor type 8 Homo sapiens 0.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203834&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10006907 104082792 CHEMBL386308 ZINC35242682 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373137 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCCCN InChI=1S/C28H34N4O4S/c1-20-8-2-3-9-22(20)28(34)30-25-13-14-26(24-11-5-4-10-23(24)25)37(35,36)31-21-15-18-32(19-16-21)27(33)12-6-7-17-29/h2-5,8-11,13-14,21,31H,6-7,12,15-19,29H2,1H3,(H,30,34) SAAGNUZHTSXRHL-UHFFFAOYSA-N 50203835 CHEMBL221638::N-[4-({[1-(5-aminopentanoyl)piperidin-4-yl]amino}sulfonyl)-1-naphthyl]-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 199 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203835&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105809 104082793 CHEMBL221638 ZINC35242582 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373138 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)N2CCCCC2)c2ccccc12 InChI=1S/C24H32N4O5S/c1-2-33-24(30)28-16-12-18(13-17-28)26-34(31,32)22-11-10-21(19-8-4-5-9-20(19)22)25-23(29)27-14-6-3-7-15-27/h4-5,8-11,18,26H,2-3,6-7,12-17H2,1H3,(H,25,29) PASQPRKTBYZODX-UHFFFAOYSA-N 50203836 CHEMBL219589::ethyl 4-[({4-[(piperidin-1-ylcarbonyl)amino]-1-naphthyl}-sulfonyl)amino]piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens 125.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203836&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105831 104082794 CHEMBL219589 ZINC35242592 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373139 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccoc2)c2ccccc12 InChI=1S/C24H27N3O5S/c1-2-5-23(28)27-13-10-18(11-14-27)26-33(30,31)22-9-8-21(19-6-3-4-7-20(19)22)25-24(29)17-12-15-32-16-17/h3-4,6-9,12,15-16,18,26H,2,5,10-11,13-14H2,1H3,(H,25,29) KQHCOEKQMDCNLY-UHFFFAOYSA-N 50203839 CHEMBL219432::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3-furamide C-C chemokine receptor type 8 Homo sapiens 1519 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203839&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105862 104082797 CHEMBL219432 ZINC35242649 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373140 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCCCC1)c1ccccc1 InChI=1S/C23H24N2O3S/c26-23(17-9-3-1-4-10-17)24-21-15-16-22(20-14-8-7-13-19(20)21)29(27,28)25-18-11-5-2-6-12-18/h1,3-4,7-10,13-16,18,25H,2,5-6,11-12H2,(H,24,26) KLDPHAYIIULOBY-UHFFFAOYSA-N 50203837 CHEMBL218503::N-(4-cyclohexylsulfamoyl-naphthalen-1-yl)-benzamide C-C chemokine receptor type 8 Homo sapiens 4.4 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203837&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11452569 104082795 CHEMBL218503 ZINC38151312 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373141 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CCN(C)CC2)c2ccccc12 InChI=1S/C26H36N4O4S/c1-3-6-25(31)30-17-13-20(14-18-30)28-35(33,34)24-10-9-23(21-7-4-5-8-22(21)24)27-26(32)19-11-15-29(2)16-12-19/h4-5,7-10,19-20,28H,3,6,11-18H2,1-2H3,(H,27,32) PDIBBCTZVFJGTC-UHFFFAOYSA-N 50203838 1-methyl-piperidine-4-carboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide::CHEMBL376070 C-C chemokine receptor type 8 Homo sapiens >1900 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203838&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105785 104082796 CHEMBL376070 ZINC35242550 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373142 CN(C)c1ccc(cc1)C(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C32H34N4O4S/c1-22-8-4-5-9-26(22)31(37)33-29-16-17-30(28-11-7-6-10-27(28)29)41(39,40)34-24-18-20-36(21-19-24)32(38)23-12-14-25(15-13-23)35(2)3/h4-17,24,34H,18-21H2,1-3H3,(H,33,37) BHZXLKKDUQLDFB-UHFFFAOYSA-N 50203840 CHEMBL221078::N-{4-[({1-[4-(dimethylamino)benzoyl]piperidin-4-yl}amino)-sulfonyl]-1-naphthyl}-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 114 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203840&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105813 104082798 CHEMBL221078 ZINC36184928 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373143 CCCNC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C27H32N4O4S/c1-3-16-28-27(33)31-17-14-20(15-18-31)30-36(34,35)25-13-12-24(22-10-6-7-11-23(22)25)29-26(32)21-9-5-4-8-19(21)2/h4-13,20,30H,3,14-18H2,1-2H3,(H,28,33)(H,29,32) GWEPMKCQULHTKT-UHFFFAOYSA-N 50203841 4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]-N-propylpiperidine-1-carboxamide::CHEMBL385288 C-C chemokine receptor type 8 Homo sapiens 77.4 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203841&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105820 104082799 CHEMBL385288 ZINC03962053 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373144 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(C)cc2)c2ccccc12 InChI=1S/C27H31N3O4S/c1-3-6-26(31)30-17-15-21(16-18-30)29-35(33,34)25-14-13-24(22-7-4-5-8-23(22)25)28-27(32)20-11-9-19(2)10-12-20/h4-5,7-14,21,29H,3,6,15-18H2,1-2H3,(H,28,32) AIXNEOOSDYSRAM-UHFFFAOYSA-N 50203842 CHEMBL222062::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-4-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 9.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203842&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105771 104082800 CHEMBL222062 ZINC35242529 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373145 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(N)c2ccccc12 InChI=1S/C18H23N3O4S/c1-2-25-18(22)21-11-9-13(10-12-21)20-26(23,24)17-8-7-16(19)14-5-3-4-6-15(14)17/h3-8,13,20H,2,9-12,19H2,1H3 FQJWVYWTOPOBBF-UHFFFAOYSA-N 50203843 CHEMBL374916::ethyl 4-(1-aminonaphthalene-4-sulfonamido)piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens >5000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203843&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105843 104082801 CHEMBL374916 ZINC35242617 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373146 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)Nc1ccccc1)c1ccccc1 InChI=1S/C23H18N2O3S/c26-23(17-9-3-1-4-10-17)24-21-15-16-22(20-14-8-7-13-19(20)21)29(27,28)25-18-11-5-2-6-12-18/h1-16,25H,(H,24,26) WLKYPFNFQJMVGH-UHFFFAOYSA-N 50203847 CHEMBL222110::N-(4-phenylsulfamoyl-naphthalen-1-yl)-benzamide C-C chemokine receptor type 8 Homo sapiens 1760 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203847&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11774008 104082805 CHEMBL222110 ZINC36184924 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373147 CCCC(=O)N1CC(C1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C25H27N3O4S/c1-3-8-24(29)28-15-18(16-28)27-33(31,32)23-14-13-22(20-11-6-7-12-21(20)23)26-25(30)19-10-5-4-9-17(19)2/h4-7,9-14,18,27H,3,8,15-16H2,1-2H3,(H,26,30) GTSAXRXSYRUOES-UHFFFAOYSA-N 50203848 CHEMBL217979::N-(4-{[(1-butyrylazetidin-3-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 50.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203848&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105844 104082806 CHEMBL217979 ZINC35242619 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373148 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CN InChI=1S/C25H28N4O4S/c1-17-6-2-3-7-19(17)25(31)27-22-10-11-23(21-9-5-4-8-20(21)22)34(32,33)28-18-12-14-29(15-13-18)24(30)16-26/h2-11,18,28H,12-16,26H2,1H3,(H,27,31) UJTIDXNZRJUKLM-UHFFFAOYSA-N 50203849 CHEMBL221904::N-{4-[1-(2-amino-acetyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 4.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203849&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10254576 104082807 CHEMBL221904 ZINC35242678 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373149 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C(CC)CC)c2ccccc12 InChI=1S/C25H35N3O4S/c1-4-9-24(29)28-16-14-19(15-17-28)27-33(31,32)23-13-12-22(20-10-7-8-11-21(20)23)26-25(30)18(5-2)6-3/h7-8,10-13,18-19,27H,4-6,9,14-17H2,1-3H3,(H,26,30) FQDIUMUUJRYNSD-UHFFFAOYSA-N 50203844 CHEMBL385654::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-ethylbutanamide C-C chemokine receptor type 8 Homo sapiens 638.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203844&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105786 104082802 CHEMBL385654 ZINC35242552 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373150 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CCC2)c2ccccc12 InChI=1S/C24H31N3O4S/c1-2-6-23(28)27-15-13-18(14-16-27)26-32(30,31)22-12-11-21(19-9-3-4-10-20(19)22)25-24(29)17-7-5-8-17/h3-4,9-12,17-18,26H,2,5-8,13-16H2,1H3,(H,25,29) LJMULFZNNMBUQL-UHFFFAOYSA-N 50203845 CHEMBL218554::cyclobutanecarboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide C-C chemokine receptor type 8 Homo sapiens 57.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203845&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105783 104082803 CHEMBL218554 ZINC35242546 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373151 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NCc2ccccc2)c2ccccc12 InChI=1S/C25H29N3O4S/c1-2-32-25(29)28-16-14-20(15-17-28)27-33(30,31)24-13-12-23(21-10-6-7-11-22(21)24)26-18-19-8-4-3-5-9-19/h3-13,20,26-27H,2,14-18H2,1H3 UMUZDXSYISWZQG-UHFFFAOYSA-N 50203846 4-[4-(benzylamino-methyl)-naphthalene-1-sulfonylamino]piperidine-1-carboxylic acid ethyl ester::CHEMBL375880 C-C chemokine receptor type 8 Homo sapiens 45.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203846&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44419031 104082804 CHEMBL375880 ZINC36184922 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373152 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)N1CCCCC1 InChI=1S/C29H34N4O4S/c1-21-9-3-4-10-23(21)28(34)30-26-13-14-27(25-12-6-5-11-24(25)26)38(36,37)31-22-15-19-33(20-16-22)29(35)32-17-7-2-8-18-32/h3-6,9-14,22,31H,2,7-8,15-20H2,1H3,(H,30,34) XBNXUTMILCXSPR-UHFFFAOYSA-N 50203850 2-methyl-N-{4-[1-(piperidine-1-carbonyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-benzamide::CHEMBL385108 C-C chemokine receptor type 8 Homo sapiens 4.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203850&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105892 104082808 CHEMBL385108 ZINC36184930 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373153 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccnc2C)c2ccccc12 InChI=1S/C26H30N4O4S/c1-3-7-25(31)30-16-13-19(14-17-30)29-35(33,34)24-12-11-23(21-8-4-5-9-22(21)24)28-26(32)20-10-6-15-27-18(20)2/h4-6,8-12,15,19,29H,3,7,13-14,16-17H2,1-2H3,(H,28,32) WXEBVBGVMONLKG-UHFFFAOYSA-N 50203851 CHEMBL441870::N-[4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-2-methyl-nicotinamide C-C chemokine receptor type 8 Homo sapiens 280 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203851&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105865 104082809 CHEMBL441870 ZINC35242653 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373154 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2)c2ccccc12 InChI=1S/C26H28FN3O4S/c1-2-6-25(31)30-15-13-20(14-16-30)29-35(33,34)24-12-11-23(21-9-3-4-10-22(21)24)28-26(32)18-7-5-8-19(27)17-18/h3-5,7-12,17,20,29H,2,6,13-16H2,1H3,(H,28,32) IWDRXZJZYMGZJF-UHFFFAOYSA-N 50203852 CHEMBL221639::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3-fluorobenzamide C-C chemokine receptor type 8 Homo sapiens 20 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203852&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105859 104082810 CHEMBL221639 ZINC35242642 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373155 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)N1CCC1 InChI=1S/C27H30N4O4S/c1-19-7-2-3-8-21(19)26(32)28-24-11-12-25(23-10-5-4-9-22(23)24)36(34,35)29-20-13-17-31(18-14-20)27(33)30-15-6-16-30/h2-5,7-12,20,29H,6,13-18H2,1H3,(H,28,32) BSLPBMWANSWIEK-UHFFFAOYSA-N 50203853 CHEMBL221130::N-{4-[1-(azetidine-1-carbonyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 3.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203853&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105891 104082811 CHEMBL221130 ZINC35242691 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373156 COCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H29N3O5S/c1-18-7-3-4-8-20(18)26(31)27-23-11-12-24(22-10-6-5-9-21(22)23)35(32,33)28-19-13-15-29(16-14-19)25(30)17-34-2/h3-12,19,28H,13-17H2,1-2H3,(H,27,31) JTGCWCQODLRAMB-UHFFFAOYSA-N 50203855 CHEMBL221961::N-{4-[1-(2-methoxy-acetyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 15.8 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203855&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105805 104082813 CHEMBL221961 ZINC35242577 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373157 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cnccn2)c2ccccc12 InChI=1S/C24H27N5O4S/c1-2-5-23(30)29-14-10-17(11-15-29)28-34(32,33)22-9-8-20(18-6-3-4-7-19(18)22)27-24(31)21-16-25-12-13-26-21/h3-4,6-9,12-13,16-17,28H,2,5,10-11,14-15H2,1H3,(H,27,31) KDESTDXLUHNRIR-UHFFFAOYSA-N 50203854 CHEMBL222112::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-pyrazine-2-carboxamide C-C chemokine receptor type 8 Homo sapiens 1004 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203854&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105780 104082812 CHEMBL222112 ZINC35242540 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373158 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc2cccc(NC(=O)c3ccccc3)c2c1 InChI=1S/C25H27N3O5S/c1-2-33-25(30)28-15-13-20(14-16-28)27-34(31,32)21-12-11-18-9-6-10-23(22(18)17-21)26-24(29)19-7-4-3-5-8-19/h3-12,17,20,27H,2,13-16H2,1H3,(H,26,29) RVSORAYPURWCNM-UHFFFAOYSA-N 50203856 4-(8-benzoylamino-naphthalene-2-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL386987 C-C chemokine receptor type 8 Homo sapiens 2033 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203856&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105895 104082814 CHEMBL386987 ZINC35242696 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373159 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1cccc2c(NC(=O)c3ccccc3)cccc12 InChI=1S/C25H27N3O5S/c1-2-33-25(30)28-16-14-19(15-17-28)27-34(31,32)23-13-7-10-20-21(23)11-6-12-22(20)26-24(29)18-8-4-3-5-9-18/h3-13,19,27H,2,14-17H2,1H3,(H,26,29) JFSHHWXYMOFROK-UHFFFAOYSA-N 50203857 CHEMBL218037::ethyl 4-({[5-(benzoylamino)-1-naphthyl]sulfonyl}amino)-piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens 2.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203857&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 9982672 104082815 CHEMBL218037 ZINC36184934 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373160 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cc(C)nc(Cl)c2)c2ccccc12 InChI=1S/C26H29ClN4O4S/c1-3-6-25(32)31-13-11-19(12-14-31)30-36(34,35)23-10-9-22(20-7-4-5-8-21(20)23)29-26(33)18-15-17(2)28-24(27)16-18/h4-5,7-10,15-16,19,30H,3,6,11-14H2,1-2H3,(H,29,33) RWDVQSILOAYKQI-UHFFFAOYSA-N 50203858 CHEMBL374964::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-chloro-6-methylisonicotinamide C-C chemokine receptor type 8 Homo sapiens 43.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203858&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105779 104082816 CHEMBL374964 ZINC35242538 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373161 CCCC(=O)N1CCC(C1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H29N3O4S/c1-3-8-25(30)29-16-15-19(17-29)28-34(32,33)24-14-13-23(21-11-6-7-12-22(21)24)27-26(31)20-10-5-4-9-18(20)2/h4-7,9-14,19,28H,3,8,15-17H2,1-2H3,(H,27,31) LSBLBSMFNCZRSR-UHFFFAOYSA-N 50203860 ((+/-)-N-(4-{[(1-butyrylpyrrolidin-3-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide::CHEMBL219327 C-C chemokine receptor type 8 Homo sapiens 34.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203860&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105832 104082818 CHEMBL219327 ZINC35242596 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373162 CCNC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H30N4O4S/c1-3-27-26(32)30-16-14-19(15-17-30)29-35(33,34)24-13-12-23(21-10-6-7-11-22(21)24)28-25(31)20-9-5-4-8-18(20)2/h4-13,19,29H,3,14-17H2,1-2H3,(H,27,32)(H,28,31) RXVHXNRLCGBOHY-UHFFFAOYSA-N 50203859 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid ethylamide::CHEMBL220701 C-C chemokine receptor type 8 Homo sapiens 2.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203859&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105889 104082817 CHEMBL220701 ZINC35242690 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373163 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccnc2)c2ccccc12 InChI=1S/C25H28N4O4S/c1-2-6-24(30)29-15-12-19(13-16-29)28-34(32,33)23-11-10-22(20-8-3-4-9-21(20)23)27-25(31)18-7-5-14-26-17-18/h3-5,7-11,14,17,19,28H,2,6,12-13,15-16H2,1H3,(H,27,31) GZQRNMNMUFHNJZ-UHFFFAOYSA-N 50203861 CHEMBL218555::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-nicotinamide C-C chemokine receptor type 8 Homo sapiens 885.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203861&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105866 104082819 CHEMBL218555 ZINC35242655 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373164 CN(c1ccccc1)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C24H20N2O3S/c1-26(19-12-6-3-7-13-19)30(28,29)23-17-16-22(20-14-8-9-15-21(20)23)25-24(27)18-10-4-2-5-11-18/h2-17H,1H3,(H,25,27) CVBPCHAWPDLWBY-UHFFFAOYSA-N 50203862 CHEMBL218502::N-[4-(methyl-phenyl-sulfamoyl)-naphthalen-1-yl]-benzamide C-C chemokine receptor type 8 Homo sapiens >44000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203862&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105759 104082820 CHEMBL218502 ZINC35242510 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373165 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2C)c2ccccc12 InChI=1S/C26H29N3O5S/c1-3-34-26(31)29-16-14-19(15-17-29)28-35(32,33)24-13-12-22(20-9-5-6-10-21(20)24)25(30)27-23-11-7-4-8-18(23)2/h4-13,19,28H,3,14-17H2,1-2H3,(H,27,30) LITJWFBBLZHRQM-UHFFFAOYSA-N 50203866 4-(4-o-tolylcarbamoyl-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL375315 C-C chemokine receptor type 8 Homo sapiens 5.21 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203866&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10391077 104082824 CHEMBL375315 ZINC36184918 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373166 CC(C)(C)OC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C27H31N3O5S/c1-27(2,3)35-26(32)30-17-15-20(16-18-30)29-36(33,34)24-14-13-23(21-11-7-8-12-22(21)24)28-25(31)19-9-5-4-6-10-19/h4-14,20,29H,15-18H2,1-3H3,(H,28,31) OEOQILOGGZQWPK-UHFFFAOYSA-N 50203865 4-(4-benzoylamino-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid tert-butyl ester::CHEMBL376076 C-C chemokine receptor type 8 Homo sapiens 15.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203865&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105760 104082823 CHEMBL376076 ZINC35242512 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373167 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)CC(C)(C)C)c2ccccc12 InChI=1S/C25H35N3O4S/c1-5-8-24(30)28-15-13-18(14-16-28)27-33(31,32)22-12-11-21(19-9-6-7-10-20(19)22)26-23(29)17-25(2,3)4/h6-7,9-12,18,27H,5,8,13-17H2,1-4H3,(H,26,29) UYKCFWHTXFILEK-UHFFFAOYSA-N 50203863 CHEMBL220651::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3,3-dimethylbutanamide C-C chemokine receptor type 8 Homo sapiens 612.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203863&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105787 104082821 CHEMBL220651 ZINC35242554 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373168 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C26H29N3O4S/c1-2-8-25(30)29-17-15-20(16-18-29)28-34(32,33)24-14-13-23(21-11-6-7-12-22(21)24)27-26(31)19-9-4-3-5-10-19/h3-7,9-14,20,28H,2,8,15-18H2,1H3,(H,27,31) LJGJTODNHSXQOA-UHFFFAOYSA-N 50203864 CHEMBL426551::N-(4-{[(1-butyrylpiperidin-4-yl)amino]-sulfonyl}-1-naphthyl)benzamide C-C chemokine receptor type 8 Homo sapiens 12.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203864&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105857 104082822 CHEMBL426551 ZINC35242638 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373169 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc2cc(NC(=O)c3ccccc3C)ccc2c1 InChI=1S/C26H29N3O5S/c1-3-34-26(31)29-14-12-21(13-15-29)28-35(32,33)23-11-9-19-16-22(10-8-20(19)17-23)27-25(30)24-7-5-4-6-18(24)2/h4-11,16-17,21,28H,3,12-15H2,1-2H3,(H,27,30) LGFZGHXHUBICGF-UHFFFAOYSA-N 50203867 4-[6-(2-methyl-benzoylamino)-naphthalene-2-sulfonylamino]-piperidine-1-carboxylic acid ethyl ester::CHEMBL373893 C-C chemokine receptor type 8 Homo sapiens >44000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203867&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44419086 104082825 CHEMBL373893 ZINC40754013 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373170 CN(C)C(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H30N4O4S/c1-18-8-4-5-9-20(18)25(31)27-23-12-13-24(22-11-7-6-10-21(22)23)35(33,34)28-19-14-16-30(17-15-19)26(32)29(2)3/h4-13,19,28H,14-17H2,1-3H3,(H,27,31) FUHOZCXIEPHKEL-UHFFFAOYSA-N 50203871 4-({[4-(benzoylamino)-1-naphthyl]sulfonyl}amino)-N,N-dimethylpiperidine-1-carboxamide::CHEMBL376910 C-C chemokine receptor type 8 Homo sapiens 1.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203871&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105822 104082829 CHEMBL376910 ZINC35242590 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373171 CN1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C22H23N3O3S/c1-24-13-15-25(16-14-24)29(27,28)21-12-11-20(18-9-5-6-10-19(18)21)23-22(26)17-7-3-2-4-8-17/h2-12H,13-16H2,1H3,(H,23,26) CJEPAZIABMNFAY-UHFFFAOYSA-N 50203872 CHEMBL384534::N-[4-(4-methyl-piperazine-1-sulfonyl)-naphthalen-1-yl]benzamide C-C chemokine receptor type 8 Homo sapiens >30000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203872&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11212011 104082830 CHEMBL384534 ZINC40764354 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373172 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(O)c2ccccc12 InChI=1S/C18H22N2O5S/c1-2-25-18(22)20-11-9-13(10-12-20)19-26(23,24)17-8-7-16(21)14-5-3-4-6-15(14)17/h3-8,13,19,21H,2,9-12H2,1H3 OAORSCIBDHUGSH-UHFFFAOYSA-N 50203873 CHEMBL218640::ethyl 4-(1-hydroxynaphthalene-4-sulfonamido)piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens >5000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203873&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105798 104082831 CHEMBL218640 ZINC35242569 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373173 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)c3ccccc23)cc1 InChI=1S/C24H20N2O4S/c1-30-19-13-11-18(12-14-19)26-31(28,29)23-16-15-22(20-9-5-6-10-21(20)23)25-24(27)17-7-3-2-4-8-17/h2-16,26H,1H3,(H,25,27) WRPLZERXEQKXIY-UHFFFAOYSA-N 50203868 CHEMBL412116::N-[4-(4-methoxy-phenylsulfamoyl)-naphthalen-1-yl]-benzamide C-C chemokine receptor type 8 Homo sapiens 42.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203868&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 3384970 104082826 CHEMBL412116 ZINC03146695 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373174 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)OCCCN1CCCC1 InChI=1S/C31H38N4O5S/c1-23-9-2-3-10-25(23)30(36)32-28-13-14-29(27-12-5-4-11-26(27)28)41(38,39)33-24-15-20-35(21-16-24)31(37)40-22-8-19-34-17-6-7-18-34/h2-5,9-14,24,33H,6-8,15-22H2,1H3,(H,32,36) BRFSLLFZOHATFX-UHFFFAOYSA-N 50203869 3-pyrrolidin-1-ylpropyl 4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate::CHEMBL374527 C-C chemokine receptor type 8 Homo sapiens 4.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203869&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105817 104082827 CHEMBL374527 ZINC38151319 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373175 CN(C)CCCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C29H36N4O5S/c1-21-9-4-5-10-23(21)28(34)30-26-13-14-27(25-12-7-6-11-24(25)26)39(36,37)31-22-15-18-33(19-16-22)29(35)38-20-8-17-32(2)3/h4-7,9-14,22,31H,8,15-20H2,1-3H3,(H,30,34) NNTFZCYXELBMNG-UHFFFAOYSA-N 50203870 3-(dimethylamino)propyl 4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate::CHEMBL218369 C-C chemokine receptor type 8 Homo sapiens 9.8 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203870&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105815 104082828 CHEMBL218369 ZINC38151322 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373176 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)NCc1ccncc1)c1ccccc1 InChI=1S/C23H19N3O3S/c27-23(18-6-2-1-3-7-18)26-21-10-11-22(20-9-5-4-8-19(20)21)30(28,29)25-16-17-12-14-24-15-13-17/h1-15,25H,16H2,(H,26,27) IEOQBNYYSAIFCL-UHFFFAOYSA-N 50203874 CHEMBL385287::N-{4-[(pyridin-4-ylmethyl)-sulfamoyl]-naphthalen-1-yl}-benzamide C-C chemokine receptor type 8 Homo sapiens 3277 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203874&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11384528 104082832 CHEMBL385287 ZINC36184926 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373177 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)[C@@H]1CCCN1 InChI=1S/C28H32N4O4S/c1-19-7-2-3-8-21(19)27(33)30-24-12-13-26(23-10-5-4-9-22(23)24)37(35,36)31-20-14-17-32(18-15-20)28(34)25-11-6-16-29-25/h2-5,7-10,12-13,20,25,29,31H,6,11,14-18H2,1H3,(H,30,33)/t25-/m0/s1 GKEJTJFRAKDFAV-VWLOTQADSA-N 50203834 2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]piperidin-4-yl}amino)sulfonyl]-1-naphthyl}benzamide::2-methyl-N-{4-[({1-[(2S)-pyrrolidin-2-ylcarbonyl]piperidin-4-yl}amino)sulfonyl]-1-naphthyl}benzamide)::CHEMBL386308 C-C chemokine receptor type 8 Homo sapiens 0.700 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203834&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10006907 104082792 CHEMBL386308 ZINC35242682 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373178 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CO InChI=1S/C25H27N3O5S/c1-17-6-2-3-7-19(17)25(31)26-22-10-11-23(21-9-5-4-8-20(21)22)34(32,33)27-18-12-14-28(15-13-18)24(30)16-29/h2-11,18,27,29H,12-16H2,1H3,(H,26,31) DOACUNOCKVLWFV-UHFFFAOYSA-N 50203878 CHEMBL218036::N-{4-[1-(2-hydroxy-acetyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 5.4 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203878&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105877 104082836 CHEMBL218036 ZINC35242676 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373179 CCN(CC)CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C31H40N4O4S/c1-4-34(5-2)20-10-15-30(36)35-21-18-24(19-22-35)33-40(38,39)29-17-16-28(26-13-8-9-14-27(26)29)32-31(37)25-12-7-6-11-23(25)3/h6-9,11-14,16-17,24,33H,4-5,10,15,18-22H2,1-3H3,(H,32,37) XFRHBBPDPCGXOJ-UHFFFAOYSA-N 50203879 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid (3-diethylamino-propyl)-amide::CHEMBL219487 C-C chemokine receptor type 8 Homo sapiens 566.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203879&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105830 104082837 CHEMBL219487 ZINC36184932 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373180 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)Nc1ccccc1 InChI=1S/C30H30N4O4S/c1-21-9-5-6-12-24(21)29(35)32-27-15-16-28(26-14-8-7-13-25(26)27)39(37,38)33-23-17-19-34(20-18-23)30(36)31-22-10-3-2-4-11-22/h2-16,23,33H,17-20H2,1H3,(H,31,36)(H,32,35) KHXFJRHIHZXAEQ-UHFFFAOYSA-N 50203880 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid phenylamide::CHEMBL387161 C-C chemokine receptor type 8 Homo sapiens 108 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203880&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105890 104082838 CHEMBL387161 ZINC36184927 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373181 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H29N3O5S/c1-3-34-26(31)29-16-14-19(15-17-29)28-35(32,33)24-13-12-23(21-10-6-7-11-22(21)24)27-25(30)20-9-5-4-8-18(20)2/h4-13,19,28H,3,14-17H2,1-2H3,(H,27,30) LGJRRERRFSZFTJ-UHFFFAOYSA-N 50203881 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid ethyl ester::CHEMBL218375 C-C chemokine receptor type 8 Homo sapiens 1.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203881&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105788 104082839 CHEMBL218375 ZINC35242556 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373182 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)OCCCN1CCc2ccccc2C1 InChI=1S/C36H40N4O5S/c1-26-9-2-5-12-30(26)35(41)37-33-15-16-34(32-14-7-6-13-31(32)33)46(43,44)38-29-18-22-40(23-19-29)36(42)45-24-8-20-39-21-17-27-10-3-4-11-28(27)25-39/h2-7,9-16,29,38H,8,17-25H2,1H3,(H,37,41) NBPJPRSOJNEFIA-UHFFFAOYSA-N 50203886 3-(3,4-dihydroisoquinolin-2(1H)-yl)propyl 4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate::CHEMBL221712 C-C chemokine receptor type 8 Homo sapiens 28.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203886&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105887 104082844 CHEMBL221712 ZINC49942503 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373183 CCN(CC)CCCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C31H40N4O5S/c1-4-34(5-2)19-10-22-40-31(37)35-20-17-24(18-21-35)33-41(38,39)29-16-15-28(26-13-8-9-14-27(26)29)32-30(36)25-12-7-6-11-23(25)3/h6-9,11-16,24,33H,4-5,10,17-22H2,1-3H3,(H,32,36) OUUXOBPMSJBDDF-UHFFFAOYSA-N 50203887 3-(diethylamino)propyl 4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate::CHEMBL217984 C-C chemokine receptor type 8 Homo sapiens 14.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203887&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105885 104082845 CHEMBL217984 ZINC38151320 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373184 COc1ccc(NS(=O)(=O)c2ccc(N(C)C(=O)c3ccccc3)c3ccccc23)cc1 InChI=1S/C25H22N2O4S/c1-27(25(28)18-8-4-3-5-9-18)23-16-17-24(22-11-7-6-10-21(22)23)32(29,30)26-19-12-14-20(31-2)15-13-19/h3-17,26H,1-2H3 XKAVKXPPGUXLFR-UHFFFAOYSA-N 50203888 CHEMBL221396::N-(4-{[(4-methoxyphenyl)amino]sulfonyl}-1-naphthyl)-N-methylbenzamide C-C chemokine receptor type 8 Homo sapiens >15000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203888&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105834 104082846 CHEMBL221396 ZINC35242601 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373185 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(OC(=O)c2ccccc2)c2ccccc12 InChI=1S/C25H26N2O6S/c1-2-32-25(29)27-16-14-19(15-17-27)26-34(30,31)23-13-12-22(20-10-6-7-11-21(20)23)33-24(28)18-8-4-3-5-9-18/h3-13,19,26H,2,14-17H2,1H3 CZNQUIPMFXMQEZ-UHFFFAOYSA-N 50203889 CHEMBL426207::ethyl 4-({[4-(benzoyloxy)-1-naphthyl]sulfonyl}amino)-piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens 16.4 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203889&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105799 104082847 CHEMBL426207 ZINC35242571 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373186 CN1CCN(CC1)C(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C29H35N5O4S/c1-21-7-3-4-8-23(21)28(35)30-26-11-12-27(25-10-6-5-9-24(25)26)39(37,38)31-22-13-15-33(16-14-22)29(36)34-19-17-32(2)18-20-34/h3-12,22,31H,13-20H2,1-2H3,(H,30,35) OHPIAISBTHGTMM-UHFFFAOYSA-N 50203882 2-methyl-N-{4-[1-(4-methyl-piperazine-1-carbonyl)-piperidin-4-ylsulfamoyl]-aphthalen-1-yl}-benzamide::CHEMBL221251 C-C chemokine receptor type 8 Homo sapiens 4.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203882&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105824 104082840 CHEMBL221251 ZINC28604049 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373187 CCCC(=O)N1CCC(CC1)NC(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C28H31N3O3/c1-3-8-26(32)31-17-15-20(16-18-31)29-28(34)24-13-14-25(23-12-7-6-11-22(23)24)30-27(33)21-10-5-4-9-19(21)2/h4-7,9-14,20H,3,8,15-18H2,1-2H3,(H,29,34)(H,30,33) UELPQLUPMUEUAK-UHFFFAOYSA-N 50203883 CHEMBL374963::N-(1-butyrylpiperidin-4-yl)-4-[(2-methylbenzoyl)amino]-1-naphthamide C-C chemokine receptor type 8 Homo sapiens >3300 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203883&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105836 104082841 CHEMBL374963 ZINC35242604 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373188 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CCCC2)c2ccccc12 InChI=1S/C25H33N3O4S/c1-2-7-24(29)28-16-14-19(15-17-28)27-33(31,32)23-13-12-22(20-10-5-6-11-21(20)23)26-25(30)18-8-3-4-9-18/h5-6,10-13,18-19,27H,2-4,7-9,14-17H2,1H3,(H,26,30) UEPSIVUUIZKFBU-UHFFFAOYSA-N 50203884 CHEMBL376517::cyclopentanecarboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide C-C chemokine receptor type 8 Homo sapiens 365 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203884&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105868 104082842 CHEMBL376517 ZINC35242660 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373189 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccncc2)c2ccccc12 InChI=1S/C24H26N4O5S/c1-2-33-24(30)28-15-11-18(12-16-28)27-34(31,32)22-8-7-21(19-5-3-4-6-20(19)22)26-23(29)17-9-13-25-14-10-17/h3-10,13-14,18,27H,2,11-12,15-16H2,1H3,(H,26,29) ZPGHKHDPDWADMY-UHFFFAOYSA-N 50203885 CHEMBL217965::ethyl 4-({[4-(Isonicotinoylamino)-1-naphthyl]sulfonyl}amino)-piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens 100 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203885&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105782 104082843 CHEMBL217965 ZINC35242544 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373190 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)N1CCOCC1)c1ccccc1 InChI=1S/C21H20N2O4S/c24-21(16-6-2-1-3-7-16)22-19-10-11-20(18-9-5-4-8-17(18)19)28(25,26)23-12-14-27-15-13-23/h1-11H,12-15H2,(H,22,24) NBPMEEITQYFENA-UHFFFAOYSA-N 50203890 CHEMBL218207::N-(4-(morpholinosulfonyl)naphthalen-1-yl)benzamide C-C chemokine receptor type 8 Homo sapiens 7745 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203890&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1099153 104082848 CHEMBL218207 ZINC00823152 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373191 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)c3ccccc23)cc1 InChI=1S/C24H20N2O4S/c1-30-19-13-11-18(12-14-19)26-31(28,29)23-16-15-22(20-9-5-6-10-21(20)23)25-24(27)17-7-3-2-4-8-17/h2-16,26H,1H3,(H,25,27) WRPLZERXEQKXIY-UHFFFAOYSA-N 50203868 CHEMBL412116::N-[4-(4-methoxy-phenylsulfamoyl)-naphthalen-1-yl]-benzamide C-C chemokine receptor type 8 Homo sapiens 150 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203868&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 3384970 104082826 CHEMBL412116 ZINC03146695 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373192 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)NCc1ccccc1)c1ccccc1 InChI=1S/C24H20N2O3S/c27-24(19-11-5-2-6-12-19)26-22-15-16-23(21-14-8-7-13-20(21)22)30(28,29)25-17-18-9-3-1-4-10-18/h1-16,25H,17H2,(H,26,27) QPJKMKVTEJYYGG-UHFFFAOYSA-N 50203892 CHEMBL222111::N-{4-[(benzylamino)sulfonyl]-1-naphthyl}benzamide C-C chemokine receptor type 8 Homo sapiens 233.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203892&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11270007 104082850 CHEMBL222111 ZINC03962051 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373193 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2nccn2C)c2ccccc12 InChI=1S/C24H29N5O4S/c1-3-6-22(30)29-14-11-17(12-15-29)27-34(32,33)21-10-9-20(18-7-4-5-8-19(18)21)26-24(31)23-25-13-16-28(23)2/h4-5,7-10,13,16-17,27H,3,6,11-12,14-15H2,1-2H3,(H,26,31) LMPSLVRKFHZXLL-UHFFFAOYSA-N 50203891 CHEMBL221842::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-1-methyl-1H-imidazole-2-carboxamide C-C chemokine receptor type 8 Homo sapiens 20.4 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203891&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105864 104082849 CHEMBL221842 ZINC35242651 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373194 CC1CN(CCCOC(=O)N2CCC(CC2)NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC(C)O1 InChI=1S/C33H42N4O6S/c1-23-9-4-5-10-27(23)32(38)34-30-13-14-31(29-12-7-6-11-28(29)30)44(40,41)35-26-15-18-37(19-16-26)33(39)42-20-8-17-36-21-24(2)43-25(3)22-36/h4-7,9-14,24-26,35H,8,15-22H2,1-3H3,(H,34,38) RCSMPRZXADOTLA-UHFFFAOYSA-N 50203893 3-(2,6-dimethylmorpholin-4-yl)propyl-4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}sulfonyl)amino]piperidine-1-carboxylate::CHEMBL222020 C-C chemokine receptor type 8 Homo sapiens 19.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203893&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105819 104082851 CHEMBL222020 ZINC28604002 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373195 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)N1CCOCC1 InChI=1S/C28H32N4O5S/c1-20-6-2-3-7-22(20)27(33)29-25-10-11-26(24-9-5-4-8-23(24)25)38(35,36)30-21-12-14-31(15-13-21)28(34)32-16-18-37-19-17-32/h2-11,21,30H,12-19H2,1H3,(H,29,33) ATGATFNTNVKEJF-UHFFFAOYSA-N 50203875 2-methyl-N-[4-({[1-(morpholin-4-ylcarbonyl)piperidin-4-yl]-amino}sulfonyl)-1-naphthyl]benzamide::CHEMBL218218 C-C chemokine receptor type 8 Homo sapiens 6.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203875&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105893 104082833 CHEMBL218218 ZINC36184931 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373196 CC(C)NC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C27H32N4O4S/c1-18(2)28-27(33)31-16-14-20(15-17-31)30-36(34,35)25-13-12-24(22-10-6-7-11-23(22)25)29-26(32)21-9-5-4-8-19(21)3/h4-13,18,20,30H,14-17H2,1-3H3,(H,28,33)(H,29,32) BCPVJZZVPJKYEL-UHFFFAOYSA-N 50203876 CHEMBL218350::N-isopropyl-4-[({4-[(2-methylbenzoyl)amino]-1-naphthyl}-sulfonyl)amino]piperidine-1-carboxamide C-C chemokine receptor type 8 Homo sapiens 77.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203876&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105821 104082834 CHEMBL218350 ZINC35242588 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373197 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C(CC)c2ccccc2)c2ccccc12 InChI=1S/C29H35N3O4S/c1-3-10-28(33)32-19-17-22(18-20-32)31-37(35,36)27-16-15-26(24-13-8-9-14-25(24)27)30-29(34)23(4-2)21-11-6-5-7-12-21/h5-9,11-16,22-23,31H,3-4,10,17-20H2,1-2H3,(H,30,34) QAELIZCZGHKYIN-UHFFFAOYSA-N 50203877 CHEMBL220652::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-phenylbutanamide C-C chemokine receptor type 8 Homo sapiens 7.65 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203877&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105856 104082835 CHEMBL220652 ZINC35242636 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373199 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)N1CCCCC1)c1ccccc1 InChI=1S/C22H22N2O3S/c25-22(17-9-3-1-4-10-17)23-20-13-14-21(19-12-6-5-11-18(19)20)28(26,27)24-15-7-2-8-16-24/h1,3-6,9-14H,2,7-8,15-16H2,(H,23,25) NUDZBBIFFZEAEK-UHFFFAOYSA-N 50203898 CHEMBL217908::N-(4-(piperidin-1-ylsulfonyl)naphthalen-1-yl)benzamide C-C chemokine receptor type 8 Homo sapiens >30000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203898&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 3594744 104082856 CHEMBL217908 ZINC03109416 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373200 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NCCCc2ccccc2)c2ccccc12 InChI=1S/C27H33N3O4S/c1-2-34-27(31)30-19-16-22(17-20-30)29-35(32,33)26-15-14-25(23-12-6-7-13-24(23)26)28-18-8-11-21-9-4-3-5-10-21/h3-7,9-10,12-15,22,28-29H,2,8,11,16-20H2,1H3 ZVACMLUWMNXCQQ-UHFFFAOYSA-N 50203895 4-{4-[(3-phenyl-propylamino)-methyl]-naphthalene-1-sulfonylamino}-piperidine-1-carboxylic acid ethyl ester::CHEMBL221345 C-C chemokine receptor type 8 Homo sapiens 32.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203895&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44419035 104082853 CHEMBL221345 ZINC36184925 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373201 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cc3ccccc3s2)c2ccccc12 InChI=1S/C28H29N3O4S2/c1-2-7-27(32)31-16-14-20(15-17-31)30-37(34,35)26-13-12-23(21-9-4-5-10-22(21)26)29-28(33)25-18-19-8-3-6-11-24(19)36-25/h3-6,8-13,18,20,30H,2,7,14-17H2,1H3,(H,29,33) UHFNHULJUGPBJO-UHFFFAOYSA-N 50203894 CHEMBL374414::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-1-benzothiophene-2-carboxamide C-C chemokine receptor type 8 Homo sapiens 23.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203894&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105777 104082852 CHEMBL374414 ZINC38151315 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373202 CCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H29N3O4S/c1-3-25(30)29-16-14-19(15-17-29)28-34(32,33)24-13-12-23(21-10-6-7-11-22(21)24)27-26(31)20-9-5-4-8-18(20)2/h4-13,19,28H,3,14-17H2,1-2H3,(H,27,31) NDVJSFPFTHADQY-UHFFFAOYSA-N 50203900 2-methyl-N-[4-(1-propionyl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-benzamide::CHEMBL220753 C-C chemokine receptor type 8 Homo sapiens 2.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203900&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105802 104082858 CHEMBL220753 ZINC03962061 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373203 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)c2ccccc12 InChI=1S/C30H37N3O4S/c1-5-8-28(34)33-19-17-23(18-20-33)32-38(36,37)27-16-15-26(24-9-6-7-10-25(24)27)31-29(35)21-11-13-22(14-12-21)30(2,3)4/h6-7,9-16,23,32H,5,8,17-20H2,1-4H3,(H,31,35) NFULGCSRYNEYAI-UHFFFAOYSA-N 50203899 4-tert-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)benzamide::CHEMBL218297 C-C chemokine receptor type 8 Homo sapiens 6.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203899&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105861 104082857 CHEMBL218297 ZINC35242647 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373204 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(CC)cc2)c2ccccc12 InChI=1S/C28H33N3O4S/c1-3-7-27(32)31-18-16-22(17-19-31)30-36(34,35)26-15-14-25(23-8-5-6-9-24(23)26)29-28(33)21-12-10-20(4-2)11-13-21/h5-6,8-15,22,30H,3-4,7,16-19H2,1-2H3,(H,29,33) CWZVZOMPFAPIDY-UHFFFAOYSA-N 50203896 CHEMBL374978::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-4-ethylbenzamide C-C chemokine receptor type 8 Homo sapiens 10.8 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203896&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105860 104082854 CHEMBL374978 ZINC35242645 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373205 CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C21H22N2O3S/c1-3-23(4-2)27(25,26)20-15-14-19(17-12-8-9-13-18(17)20)22-21(24)16-10-6-5-7-11-16/h5-15H,3-4H2,1-2H3,(H,22,24) HOPPMXHUKFSUEE-UHFFFAOYSA-N 50203897 CHEMBL376846::N-(4-diethylsulfamoyl-naphthalen-1-yl)-benzamide C-C chemokine receptor type 8 Homo sapiens >30000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203897&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105847 104082855 CHEMBL376846 ZINC35242623 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373206 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(OCc3ccccc3)cc2)c2ccccc12 InChI=1S/C33H35N3O5S/c1-2-8-32(37)36-21-19-26(20-22-36)35-42(39,40)31-18-17-30(28-11-6-7-12-29(28)31)34-33(38)25-13-15-27(16-14-25)41-23-24-9-4-3-5-10-24/h3-7,9-18,26,35H,2,8,19-23H2,1H3,(H,34,38) YDOYYIGKVCDFOT-UHFFFAOYSA-N 50203906 4-(benzyloxy)-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)benzamide::CHEMBL374274 C-C chemokine receptor type 8 Homo sapiens 24.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203906&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105776 104082864 CHEMBL374274 ZINC38151316 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373207 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2F)c2ccccc12 InChI=1S/C26H28FN3O4S/c1-2-7-25(31)30-16-14-18(15-17-30)29-35(33,34)24-13-12-23(19-8-3-4-9-20(19)24)28-26(32)21-10-5-6-11-22(21)27/h3-6,8-13,18,29H,2,7,14-17H2,1H3,(H,28,32) OFYIKZOBJLDBHO-UHFFFAOYSA-N 50203907 CHEMBL219380::N-[4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-2-fluoro-benzamide C-C chemokine receptor type 8 Homo sapiens 19.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203907&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105772 104082865 CHEMBL219380 ZINC35242532 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373208 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)c2ccccc12 InChI=1S/C25H27N3O5S/c1-2-33-25(30)28-16-14-19(15-17-28)27-34(31,32)23-13-12-22(20-10-6-7-11-21(20)23)26-24(29)18-8-4-3-5-9-18/h3-13,19,27H,2,14-17H2,1H3,(H,26,29) VPSUMVGLQZVOCZ-UHFFFAOYSA-N 50203905 4-(4-benzoylamino-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL218374 C-C chemokine receptor type 8 Homo sapiens 0.17 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203905&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10367938 104082863 CHEMBL218374 ZINC36184919 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373209 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCCN1CCOCC1 InChI=1S/C31H38N4O5S/c1-23-7-2-3-8-25(23)31(37)32-28-12-13-29(27-10-5-4-9-26(27)28)41(38,39)33-24-14-17-35(18-15-24)30(36)11-6-16-34-19-21-40-22-20-34/h2-5,7-10,12-13,24,33H,6,11,14-22H2,1H3,(H,32,37) PEXVJRSYTQCVFU-UHFFFAOYSA-N 50203909 4-[4-(2-methyl-benzoylamino)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid (3-morpholin-4-yl-propyl)-amide::CHEMBL218366 C-C chemokine receptor type 8 Homo sapiens 71 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203909&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105826 104082867 CHEMBL218366 ZINC36184933 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373210 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(C)c2)c2ccccc12 InChI=1S/C27H31N3O4S/c1-3-7-26(31)30-16-14-21(15-17-30)29-35(33,34)25-13-12-24(22-10-4-5-11-23(22)25)28-27(32)20-9-6-8-19(2)18-20/h4-6,8-13,18,21,29H,3,7,14-17H2,1-2H3,(H,28,32) QSNIDHPXWJGJKF-UHFFFAOYSA-N 50203908 CHEMBL221790::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 5.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203908&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105858 104082866 CHEMBL221790 ZINC35242640 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373212 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)c2ccccc12 InChI=1S/C26H28FN3O4S/c1-2-5-25(31)30-16-14-20(15-17-30)29-35(33,34)24-13-12-23(21-6-3-4-7-22(21)24)28-26(32)18-8-10-19(27)11-9-18/h3-4,6-13,20,29H,2,5,14-17H2,1H3,(H,28,32) LLEHETDEZNVDGI-UHFFFAOYSA-N 50203903 CHEMBL221978::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-4-fluorobenzamide C-C chemokine receptor type 8 Homo sapiens 59.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203903&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105773 104082861 CHEMBL221978 ZINC35242534 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373213 COc1ccc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)c3ccccc23)cc1 InChI=1S/C25H18N2O5S/c1-32-17-12-10-16(11-13-17)26-33(30,31)23-15-14-22(18-6-2-3-7-19(18)23)27-24(28)20-8-4-5-9-21(20)25(27)29/h2-15,26H,1H3 CAJQUHISZZKNRC-UHFFFAOYSA-N 50203901 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-naphthalene-1-sulfonic acid (4-methoxy phenyl)-amide::CHEMBL376069 C-C chemokine receptor type 8 Homo sapiens >44000 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203901&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 5335896 104082859 CHEMBL376069 ZINC16675741 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373214 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccn2)c2ccccc12 InChI=1S/C25H28N4O4S/c1-2-7-24(30)29-16-13-18(14-17-29)28-34(32,33)23-12-11-21(19-8-3-4-9-20(19)23)27-25(31)22-10-5-6-15-26-22/h3-6,8-12,15,18,28H,2,7,13-14,16-17H2,1H3,(H,27,31) QRBRZQLDYOKWNP-UHFFFAOYSA-N 50203912 CHEMBL218298::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-pyridine-2-carboxamide C-C chemokine receptor type 8 Homo sapiens 41.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203912&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105781 104082870 CHEMBL218298 ZINC35242542 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373215 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cc(C)oc2C(F)(F)F)c2ccccc12 InChI=1S/C26H28F3N3O5S/c1-3-6-23(33)32-13-11-17(12-14-32)31-38(35,36)22-10-9-21(18-7-4-5-8-19(18)22)30-25(34)20-15-16(2)37-24(20)26(27,28)29/h4-5,7-10,15,17,31H,3,6,11-14H2,1-2H3,(H,30,34) OTFMNYKFCVGZCQ-UHFFFAOYSA-N 50203913 CHEMBL217909::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-5-methyl-2-(trifluoromethyl)-3-furamide C-C chemokine receptor type 8 Homo sapiens 46.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203913&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105778 104082871 CHEMBL217909 ZINC38151313 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373216 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CC2)c2ccccc12 InChI=1S/C23H29N3O4S/c1-2-5-22(27)26-14-12-17(13-15-26)25-31(29,30)21-11-10-20(24-23(28)16-8-9-16)18-6-3-4-7-19(18)21/h3-4,6-7,10-11,16-17,25H,2,5,8-9,12-15H2,1H3,(H,24,28) RDDQQXWHCVOCBG-UHFFFAOYSA-N 50203904 CHEMBL376071::cyclopropanecarboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide C-C chemokine receptor type 8 Homo sapiens 367.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203904&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105867 104082862 CHEMBL376071 ZINC35242658 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373217 CC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C25H27N3O4S/c1-17-7-3-4-8-20(17)25(30)26-23-11-12-24(22-10-6-5-9-21(22)23)33(31,32)27-19-13-15-28(16-14-19)18(2)29/h3-12,19,27H,13-16H2,1-2H3,(H,26,30) NRPIUJMCMZZSCD-UHFFFAOYSA-N 50203910 CHEMBL221977::N-(4-{[(1-acetylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 6.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203910&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105803 104082868 CHEMBL221977 ZINC35242574 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373218 CCCC(=O)N1CCC(CC1)NCc1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C28H33N3O2/c1-3-8-27(32)31-17-15-22(16-18-31)29-19-21-13-14-26(25-12-7-6-11-24(21)25)30-28(33)23-10-5-4-9-20(23)2/h4-7,9-14,22,29H,3,8,15-19H2,1-2H3,(H,30,33) ICGHIKITHSJYDX-UHFFFAOYSA-N 50203902 CHEMBL221841::N-(4-{[(1-butyrylpiperidin-4-yl)amino]methyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens >3300 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203902&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105765 104082860 CHEMBL221841 ZINC35242522 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373219 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)c1ccccc1 InChI=1S/C30H29N3O4S/c1-21-9-5-6-12-24(21)29(34)31-27-15-16-28(26-14-8-7-13-25(26)27)38(36,37)32-23-17-19-33(20-18-23)30(35)22-10-3-2-4-11-22/h2-16,23,32H,17-20H2,1H3,(H,31,34) BGAJBPXTYAWRIL-UHFFFAOYSA-N 50203918 CHEMBL387451::N-(4-{[(1-benzoylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 81.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203918&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105882 104082876 CHEMBL387451 ZINC35242685 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373220 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)N1CCCC1 InChI=1S/C28H32N4O4S/c1-20-8-2-3-9-22(20)27(33)29-25-12-13-26(24-11-5-4-10-23(24)25)37(35,36)30-21-14-18-32(19-15-21)28(34)31-16-6-7-17-31/h2-5,8-13,21,30H,6-7,14-19H2,1H3,(H,29,33) XVLLKCMFVWAZFA-UHFFFAOYSA-N 50203919 2-methyl-N-[4-({[1-(pyrrolidin-1-ylcarbonyl)piperidin-4-yl]-amino}sulfonyl)-1-naphthyl]benzamide::CHEMBL373739 C-C chemokine receptor type 8 Homo sapiens 1.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203919&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 9984180 104082877 CHEMBL373739 ZINC36184929 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373221 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCN InChI=1S/C26H30N4O4S/c1-18-6-2-3-7-20(18)26(32)28-23-10-11-24(22-9-5-4-8-21(22)23)35(33,34)29-19-13-16-30(17-14-19)25(31)12-15-27/h2-11,19,29H,12-17,27H2,1H3,(H,28,32) IMVIBXUOEUWVME-UHFFFAOYSA-N 50203911 CHEMBL220703::N-{4-[1-(3-amino-propionyl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 11.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203911&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105807 104082869 CHEMBL220703 ZINC35242579 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373222 CCCCc1ccc(cc1)C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCC InChI=1S/C30H37N3O4S/c1-3-5-9-22-12-14-23(15-13-22)30(35)31-27-16-17-28(26-11-7-6-10-25(26)27)38(36,37)32-24-18-20-33(21-19-24)29(34)8-4-2/h6-7,10-17,24,32H,3-5,8-9,18-21H2,1-2H3,(H,31,35) NVAASLCBIDYYCA-UHFFFAOYSA-N 50203915 4-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)benzamide::CHEMBL221601 C-C chemokine receptor type 8 Homo sapiens 15.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203915&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105774 104082873 CHEMBL221601 ZINC35242536 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373223 O=C(Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCNCC1)c1ccccc1 InChI=1S/C22H23N3O3S/c26-22(16-6-2-1-3-7-16)24-20-10-11-21(19-9-5-4-8-18(19)20)29(27,28)25-17-12-14-23-15-13-17/h1-11,17,23,25H,12-15H2,(H,24,26) SGKRQGYZQYKRAK-UHFFFAOYSA-N 50203924 CHEMBL219588::N-[4-(piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-benzamide C-C chemokine receptor type 8 Homo sapiens 578 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203924&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11235229 104082882 CHEMBL219588 ZINC35242624 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373224 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)C1CCCC1 InChI=1S/C29H33N3O4S/c1-20-8-2-5-11-23(20)28(33)30-26-14-15-27(25-13-7-6-12-24(25)26)37(35,36)31-22-16-18-32(19-17-22)29(34)21-9-3-4-10-21/h2,5-8,11-15,21-22,31H,3-4,9-10,16-19H2,1H3,(H,30,33) HZDJKINTDOPCKB-UHFFFAOYSA-N 50203921 CHEMBL219433::N-[4-(1-cyclopentanecarbonyl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 9.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203921&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105804 104082879 CHEMBL219433 ZINC35242575 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373225 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C2CCCCC2)c2ccccc12 InChI=1S/C26H35N3O4S/c1-2-8-25(30)29-17-15-20(16-18-29)28-34(32,33)24-14-13-23(21-11-6-7-12-22(21)24)27-26(31)19-9-4-3-5-10-19/h6-7,11-14,19-20,28H,2-5,8-10,15-18H2,1H3,(H,27,31) NIAGNOINZWTBJX-UHFFFAOYSA-N 50203922 CHEMBL221586::cyclohexanecarboxylic acid [4-(1-butyryl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-amide C-C chemokine receptor type 8 Homo sapiens 6.1 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203922&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105784 104082880 CHEMBL221586 ZINC35242548 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373226 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(C(=O)NC2CCCCC2)c2ccccc12 InChI=1S/C25H33N3O5S/c1-2-33-25(30)28-16-14-19(15-17-28)27-34(31,32)23-13-12-22(20-10-6-7-11-21(20)23)24(29)26-18-8-4-3-5-9-18/h6-7,10-13,18-19,27H,2-5,8-9,14-17H2,1H3,(H,26,29) WNAQDGAJYADFFI-UHFFFAOYSA-N 50203917 4-(4-cyclohexylcarbamoyl-naphthalene-1-sulfonylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL221021 C-C chemokine receptor type 8 Homo sapiens 9.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203917&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11329260 104082875 CHEMBL221021 ZINC36184917 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373227 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C27H31N3O4S/c1-3-8-26(31)30-17-15-20(16-18-30)29-35(33,34)25-14-13-24(22-11-6-7-12-23(22)25)28-27(32)21-10-5-4-9-19(21)2/h4-7,9-14,20,29H,3,8,15-18H2,1-2H3,(H,28,32) LOBUISIPHBRTPI-UHFFFAOYSA-N 50203831 CHEMBL374939::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-methylbenzamide C-C chemokine receptor type 8 Homo sapiens 0.3 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203831&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 10391001 104082789 CHEMBL374939 ZINC36184921 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373228 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCCN InChI=1S/C27H32N4O4S/c1-19-7-2-3-8-21(19)27(33)29-24-12-13-25(23-10-5-4-9-22(23)24)36(34,35)30-20-14-17-31(18-15-20)26(32)11-6-16-28/h2-5,7-10,12-13,20,30H,6,11,14-18,28H2,1H3,(H,29,33) BIHPECKMBHQEHU-UHFFFAOYSA-N 50203920 CHEMBL221867::N-{4-[1-(4-amino-butyryl)-piperidin-4-ylsulfamoyl]-naphthalen-1-yl}-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 1.6 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203920&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105880 104082878 CHEMBL221867 ZINC35242680 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373229 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(OCc2ccccc2)c2ccccc12 InChI=1S/C25H28N2O5S/c1-2-31-25(28)27-16-14-20(15-17-27)26-33(29,30)24-13-12-23(21-10-6-7-11-22(21)24)32-18-19-8-4-3-5-9-19/h3-13,20,26H,2,14-18H2,1H3 LWQBKOSBMCBUHQ-UHFFFAOYSA-N 50203928 CHEMBL221789::ethyl 4-(1-(benzyloxy)naphthalene-4-sulfonamido)piperidine-1-carboxylate C-C chemokine receptor type 8 Homo sapiens 37.9 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203928&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105840 104082886 CHEMBL221789 ZINC35242613 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373230 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)C1CC1 InChI=1S/C27H29N3O4S/c1-18-6-2-3-7-21(18)26(31)28-24-12-13-25(23-9-5-4-8-22(23)24)35(33,34)29-20-14-16-30(17-15-20)27(32)19-10-11-19/h2-9,12-13,19-20,29H,10-11,14-17H2,1H3,(H,28,31) IXUDWCMFQZXPGK-UHFFFAOYSA-N 50203925 CHEMBL374979::N-[4-(1-cyclopropanecarbonyl-piperidin-4-ylsulfamoyl)-naphthalen-1-yl]-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 7.2 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203925&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105876 104082883 CHEMBL374979 ZINC35242673 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373231 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(N)=O InChI=1S/C24H26N4O4S/c1-16-6-2-3-7-18(16)23(29)26-21-10-11-22(20-9-5-4-8-19(20)21)33(31,32)27-17-12-14-28(15-13-17)24(25)30/h2-11,17,27H,12-15H2,1H3,(H2,25,30)(H,26,29) UCZAFPIJTHEDCJ-UHFFFAOYSA-N 50203926 4-(1-(2-methylbenzamido)naphthalene-4-sulfonamido)piperidine-1-carboxamide::CHEMBL373504 C-C chemokine receptor type 8 Homo sapiens 243 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203926&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105888 104082884 CHEMBL373504 ZINC35242688 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373232 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cc(nn2C)C(C)(C)C)c2ccccc12 InChI=1S/C28H37N5O4S/c1-6-9-26(34)33-16-14-19(15-17-33)31-38(36,37)24-13-12-22(20-10-7-8-11-21(20)24)29-27(35)23-18-25(28(2,3)4)30-32(23)5/h7-8,10-13,18-19,31H,6,9,14-17H2,1-5H3,(H,29,35) PIKFRYPVXAWEDT-UHFFFAOYSA-N 50203927 3-tert-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-1-methyl-1H-pyrazole-5-carboxamide::CHEMBL221650 C-C chemokine receptor type 8 Homo sapiens 37 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203927&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105863 104082885 CHEMBL221650 ZINC38151314 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373233 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NCCc2ccccc2)c2ccccc12 InChI=1S/C26H31N3O4S/c1-2-33-26(30)29-18-15-21(16-19-29)28-34(31,32)25-13-12-24(22-10-6-7-11-23(22)25)27-17-14-20-8-4-3-5-9-20/h3-13,21,27-28H,2,14-19H2,1H3 OZXMILCMXGZYIW-UHFFFAOYSA-N 50203916 4-[4-(phenethylamino-methyl)-naphthalene-1-sulfonylamino]-piperidine-1-carboxylic acid ethyl ester::CHEMBL222058 C-C chemokine receptor type 8 Homo sapiens 35.7 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203916&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44419032 104082874 CHEMBL222058 ZINC36184923 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373234 CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)CC2CCCC2)c2ccccc12 InChI=1S/C26H35N3O4S/c1-2-7-26(31)29-16-14-20(15-17-29)28-34(32,33)24-13-12-23(21-10-5-6-11-22(21)24)27-25(30)18-19-8-3-4-9-19/h5-6,10-13,19-20,28H,2-4,7-9,14-18H2,1H3,(H,27,30) LMALLKDAYQZLAW-UHFFFAOYSA-N 50203923 CHEMBL220650::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-cyclopentylacetamide C-C chemokine receptor type 8 Homo sapiens 144.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203923&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105854 104082881 CHEMBL220650 ZINC35242630 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50373235 Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)C1CNC1 InChI=1S/C27H30N4O4S/c1-18-6-2-3-7-21(18)26(32)29-24-10-11-25(23-9-5-4-8-22(23)24)36(34,35)30-20-12-14-31(15-13-20)27(33)19-16-28-17-19/h2-11,19-20,28,30H,12-17H2,1H3,(H,29,32) LQLWJFXSTXSXHY-UHFFFAOYSA-N 50203914 CHEMBL375854::N-[4-({[1-(azetidin-3-ylcarbonyl)piperidin-4-yl]amino}sulfonyl)-1-naphthyl]-2-methyl-benzamide C-C chemokine receptor type 8 Homo sapiens 1.5 ChEMBL 10.1021/jm061118e 10.7270/Q24J0DSN 17266208 Jenkins, TJ; Guan, B; Dai, M; Li, G; Lightburn, TE; Huang, S; Freeze, BS; Burdi, DF; Jacutin-Porte, S; Bennett, R; Chen, W; Minor, C; Ghosh, S; Blackburn, C; Gigstad, KM; Jones, M; Kolbeck, R; Yin, W; Smith, S; Cardillo, D; Ocain, TD; Harriman, GC Millennium Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203914&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105811 104082872 CHEMBL375854 ZINC35242584 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978886 Clc1cc(nc(c1)-c1ccccn1)-c1ccccn1 InChI=1S/C15H10ClN3/c16-11-9-14(12-5-1-3-7-17-12)19-15(10-11)13-6-2-4-8-18-13/h1-10H AHEMFMCEBIJRMU-UHFFFAOYSA-N 50401354 CHEMBL2205805 C-C chemokine receptor type 8 Homo sapiens 390 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401354&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 667748 163350378 CHEMBL2205805 ZINC00027093 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978887 Oc1cc(nc(c1)-c1ccccn1)-c1ccccn1 InChI=1S/C15H11N3O/c19-11-9-14(12-5-1-3-7-16-12)18-15(10-11)13-6-2-4-8-17-13/h1-10H,(H,18,19) HRORSVNZQWCZTD-UHFFFAOYSA-N 50401356 CHEMBL2205804 C-C chemokine receptor type 8 Homo sapiens >1000000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401356&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 619353 163350380 CHEMBL2205804 ZINC00403259 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978888 c1ccc(nc1)-c1cccc(n1)-c1ccccn1 InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H DRGAZIDRYFYHIJ-UHFFFAOYSA-N 38924 2,6-bis(2-pyridinyl)pyridine::2,6-bis(2-pyridyl)pyridine::2,6-dipyridin-2-ylpyridine::MLS000048666::SMR000060049::cid_70848 C-C chemokine receptor type 8 Homo sapiens 4900 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38924&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 70848 252619825 245199 ZINC00009065 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978889 BrCc1ccc2ccc3ccc(CBr)nc3c2n1 InChI=1S/C14H10Br2N2/c15-7-11-5-3-9-1-2-10-4-6-12(8-16)18-14(10)13(9)17-11/h1-6H,7-8H2 DGDBWGQSYCEWHT-UHFFFAOYSA-N 50401340 CHEMBL1976682 C-C chemokine receptor type 8 Homo sapiens >1000000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401340&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 353741 163350364 CHEMBL1976682 ZINC01608162 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978890 O=Cc1ccc2ccc3ccc(C=O)nc3c2n1 InChI=1S/C14H8N2O2/c17-7-11-5-3-9-1-2-10-4-6-12(8-18)16-14(10)13(9)15-11/h1-8H RHXOPVFYZBGQGA-UHFFFAOYSA-N 50401341 CHEMBL2205803 C-C chemokine receptor type 8 Homo sapiens >1000000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401341&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 602123 163350365 CHEMBL2205803 ZINC00218307 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978891 OCc1ccc2ccc3ccc(CO)nc3c2n1 InChI=1S/C14H12N2O2/c17-7-11-5-3-9-1-2-10-4-6-12(8-18)16-14(10)13(9)15-11/h1-6,17-18H,7-8H2 IEPOQNOTFLXUPQ-UHFFFAOYSA-N 50401342 CHEMBL2205802 C-C chemokine receptor type 8 Homo sapiens >1000000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401342&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 336912 163350366 CHEMBL2205802 ZINC00391500 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978892 O=Cc1ccnc2c1ccc1c(C=O)ccnc21 InChI=1S/C14H8N2O2/c17-7-9-3-5-15-13-11(9)1-2-12-10(8-18)4-6-16-14(12)13/h1-8H HCJOBZLFARGFLG-UHFFFAOYSA-N 50401343 CHEMBL2205801 C-C chemokine receptor type 8 Homo sapiens 15000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401343&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 14434082 163350367 CHEMBL2205801 ZINC95558531 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978893 Oc1ccnc2c1ccc1c(O)ccnc21 InChI=1S/C12H8N2O2/c15-9-3-5-13-11-7(9)1-2-8-10(16)4-6-14-12(8)11/h1-6H,(H,13,15)(H,14,16) SLIBCJURSADKPV-UHFFFAOYSA-N 50401357 CHEMBL1623498 C-C chemokine receptor type 8 Homo sapiens 86000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401357&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 77524 163350381 CHEMBL1623498 ZINC12341711 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978894 Clc1cc2cccnc2c2ncccc12 InChI=1S/C12H7ClN2/c13-10-7-8-3-1-5-14-11(8)12-9(10)4-2-6-15-12/h1-7H XDUUQOQFSWSZSM-UHFFFAOYSA-N 50401344 CHEMBL317115 C-C chemokine receptor type 8 Homo sapiens 3000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401344&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 77865 163350368 CHEMBL317115 ZINC00120457 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978895 Cc1cc2cccnc2c2ncccc12 InChI=1S/C13H10N2/c1-9-8-10-4-2-6-14-12(10)13-11(9)5-3-7-15-13/h2-8H,1H3 UJAQYOZROIFQHO-UHFFFAOYSA-N 50401345 CHEMBL98682 C-C chemokine receptor type 8 Homo sapiens 2000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401345&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 72791 163350369 CHEMBL98682 ZINC00120047 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978896 Cc1ccnc2c1ccc1cccnc21 InChI=1S/C13H10N2/c1-9-6-8-15-13-11(9)5-4-10-3-2-7-14-12(10)13/h2-8H,1H3 NAZZKEZTSOOCSZ-UHFFFAOYSA-N 50401346 CHEMBL316589::cid_93149 C-C chemokine receptor type 8 Homo sapiens 670 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401346&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 93149 163350370 CHEMBL316589 ZINC00120467 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978897 Cc1cnc2c(ccc3cccnc23)c1 InChI=1S/C13H10N2/c1-9-7-11-5-4-10-3-2-6-14-12(10)13(11)15-8-9/h2-8H,1H3 PBIOPYCIDCAUBZ-UHFFFAOYSA-N 50401352 CHEMBL2205810 C-C chemokine receptor type 8 Homo sapiens 670 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401352&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 15783796 163350376 CHEMBL2205810 ZINC34743784 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978898 Cc1cnc2c(ccc3c(C)c(C)cnc23)c1C InChI=1S/C16H16N2/c1-9-7-17-15-13(11(9)3)5-6-14-12(4)10(2)8-18-16(14)15/h5-8H,1-4H3 NPAXPTHCUCUHPT-UHFFFAOYSA-N 50401347 CHEMBL99384 C-C chemokine receptor type 8 Homo sapiens 480 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401347&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 74265 163350371 CHEMBL99384 ZINC00119661 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978899 Cc1ccnc2c1ccc1c(C)ccnc21 InChI=1S/C14H12N2/c1-9-5-7-15-13-11(9)3-4-12-10(2)6-8-16-14(12)13/h3-8H,1-2H3 JIVLDFFWTQYGSR-UHFFFAOYSA-N 50401348 CHEMBL593442 C-C chemokine receptor type 8 Homo sapiens 520 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401348&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search DPT 72792 163350372 CHEMBL593442 DB02586 ZINC00120461 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978900 Cc1cnc2c(ccc3cc(C)cnc23)c1 InChI=1S/C14H12N2/c1-9-5-11-3-4-12-6-10(2)8-16-14(12)13(11)15-7-9/h3-8H,1-2H3 KSACKJIWQPGKMJ-UHFFFAOYSA-N 50401353 CHEMBL2205809 C-C chemokine receptor type 8 Homo sapiens 7000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401353&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 12987698 163350377 CHEMBL2205809 ZINC39365566 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978901 Cc1ccc2ccc3ccc(C)nc3c2n1 InChI=1S/C14H12N2/c1-9-3-5-11-7-8-12-6-4-10(2)16-14(12)13(11)15-9/h3-8H,1-2H3 IYRGXJIJGHOCFS-UHFFFAOYSA-N 64740 2,9-dimethyl-1,10-phenanthroline::MLS001194484::SMR000555011::cid_65237 C-C chemokine receptor type 8 Homo sapiens >1000000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64740&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 65237 252643719 ZINC00119332 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978902 COc1ccnc(c1)-c1cc(OC)ccn1 InChI=1S/C12H12N2O2/c1-15-9-3-5-13-11(7-9)12-8-10(16-2)4-6-14-12/h3-8H,1-2H3 IMEVSAIFJKKDAP-UHFFFAOYSA-N 50401349 CHEMBL2205808 C-C chemokine receptor type 8 Homo sapiens 5400 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401349&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 2733927 163350373 CHEMBL2205808 ZINC00403962 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978903 Cc1ccnc(c1)-c1cc(C)ccn1 InChI=1S/C12H12N2/c1-9-3-5-13-11(7-9)12-8-10(2)4-6-14-12/h3-8H,1-2H3 NBPGPQJFYXNFKN-UHFFFAOYSA-N 50401350 CHEMBL101165 C-C chemokine receptor type 8 Homo sapiens 3300 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401350&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 14338 163350374 CHEMBL101165 ZINC00120136 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978904 Cc1ccc(nc1)-c1ccc(C)cn1 InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3 PTRATZCAGVBFIQ-UHFFFAOYSA-N 50401351 CHEMBL2205807 C-C chemokine receptor type 8 Homo sapiens 7500 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401351&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search EI3 15664 163350375 CHEMBL2205807 ZINC00403335 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978905 Cc1cccc(n1)-c1cccc(C)n1 InChI=1S/C12H12N2/c1-9-5-3-7-11(13-9)12-8-4-6-10(2)14-12/h3-8H,1-2H3 OHJPGUSXUGHOGE-UHFFFAOYSA-N 50401355 CHEMBL2205806 C-C chemokine receptor type 8 Homo sapiens 4800 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401355&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 20445 163350379 CHEMBL2205806 ZINC00403297 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978906 c1cnc2c(c1)ccc1cccnc21 InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H DGEZNRSVGBDHLK-UHFFFAOYSA-N 50092158 1,10-phenanthroline::CHEMBL415879::US10669227, Compound 1,10-phenanthroline::US11608309, Compound 1,10-phenanthroline::US9187406, 1,10-phenanthroline::cid_1318 C-C chemokine receptor type 8 Homo sapiens 3900 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092158&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search PHN 1318 103990358 44975 CHEMBL415879 DB02365 C00604 ZINC00164363 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978907 c1ccc(nc1)-c1ccccn1 InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H ROFVEXUMMXZLPA-UHFFFAOYSA-N 50042874 2,2'-Bipyridin::2,2'-bipyridine::2,2'-bipyridyl::2,2'-dipyridine::2,2'-dipyridyl::2-(2-pyridyl)pyridine::CHEMBL39879::US10196346, Bipyridine::alpha,alpha'-bipyridine::alpha,alpha'-bipyridyl::alpha,alpha'-dipyridine::alpha,alpha'-dipyridyl::bpy C-C chemokine receptor type 8 Homo sapiens 42000 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042874&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 0BP 1474 103974406 30351 CHEMBL39879 ZINC00105227 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978995 Clc1cc(nc(c1)-c1ccccn1)-c1ccccn1 InChI=1S/C15H10ClN3/c16-11-9-14(12-5-1-3-7-17-12)19-15(10-11)13-6-2-4-8-18-13/h1-10H AHEMFMCEBIJRMU-UHFFFAOYSA-N 50401354 CHEMBL2205805 C-C chemokine receptor type 8 Homo sapiens 398.11 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401354&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 667748 163350378 CHEMBL2205805 ZINC00027093 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978996 c1ccc(nc1)-c1cccc(n1)-c1ccccn1 InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H DRGAZIDRYFYHIJ-UHFFFAOYSA-N 38924 2,6-bis(2-pyridinyl)pyridine::2,6-bis(2-pyridyl)pyridine::2,6-dipyridin-2-ylpyridine::MLS000048666::SMR000060049::cid_70848 C-C chemokine receptor type 8 Homo sapiens 5011.87 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38924&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 70848 252619825 245199 ZINC00009065 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978997 O=Cc1ccnc2c1ccc1c(C=O)ccnc21 InChI=1S/C14H8N2O2/c17-7-9-3-5-15-13-11(9)1-2-12-10(8-18)4-6-16-14(12)13/h1-8H HCJOBZLFARGFLG-UHFFFAOYSA-N 50401343 CHEMBL2205801 C-C chemokine receptor type 8 Homo sapiens 15848.93 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401343&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 14434082 163350367 CHEMBL2205801 ZINC95558531 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978998 Oc1ccnc2c1ccc1c(O)ccnc21 InChI=1S/C12H8N2O2/c15-9-3-5-13-11-7(9)1-2-8-10(16)4-6-14-12(8)11/h1-6H,(H,13,15)(H,14,16) SLIBCJURSADKPV-UHFFFAOYSA-N 50401357 CHEMBL1623498 C-C chemokine receptor type 8 Homo sapiens 79432.82 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401357&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 77524 163350381 CHEMBL1623498 ZINC12341711 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50978999 Clc1cc2cccnc2c2ncccc12 InChI=1S/C12H7ClN2/c13-10-7-8-3-1-5-14-11(8)12-9(10)4-2-6-15-12/h1-7H XDUUQOQFSWSZSM-UHFFFAOYSA-N 50401344 CHEMBL317115 C-C chemokine receptor type 8 Homo sapiens 3162.28 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401344&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 77865 163350368 CHEMBL317115 ZINC00120457 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979000 Cc1cc2cccnc2c2ncccc12 InChI=1S/C13H10N2/c1-9-8-10-4-2-6-14-12(10)13-11(9)5-3-7-15-13/h2-8H,1H3 UJAQYOZROIFQHO-UHFFFAOYSA-N 50401345 CHEMBL98682 C-C chemokine receptor type 8 Homo sapiens 1995.26 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401345&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 72791 163350369 CHEMBL98682 ZINC00120047 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979001 Cc1ccnc2c1ccc1cccnc21 InChI=1S/C13H10N2/c1-9-6-8-15-13-11(9)5-4-10-3-2-7-14-12(10)13/h2-8H,1H3 NAZZKEZTSOOCSZ-UHFFFAOYSA-N 50401346 CHEMBL316589::cid_93149 C-C chemokine receptor type 8 Homo sapiens 630.96 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401346&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 93149 163350370 CHEMBL316589 ZINC00120467 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979002 Cc1cnc2c(ccc3cccnc23)c1 InChI=1S/C13H10N2/c1-9-7-11-5-4-10-3-2-6-14-12(10)13(11)15-8-9/h2-8H,1H3 PBIOPYCIDCAUBZ-UHFFFAOYSA-N 50401352 CHEMBL2205810 C-C chemokine receptor type 8 Homo sapiens 630.96 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401352&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 15783796 163350376 CHEMBL2205810 ZINC34743784 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979003 Cc1cnc2c(ccc3c(C)c(C)cnc23)c1C InChI=1S/C16H16N2/c1-9-7-17-15-13(11(9)3)5-6-14-12(4)10(2)8-18-16(14)15/h5-8H,1-4H3 NPAXPTHCUCUHPT-UHFFFAOYSA-N 50401347 CHEMBL99384 C-C chemokine receptor type 8 Homo sapiens 501.19 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401347&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 74265 163350371 CHEMBL99384 ZINC00119661 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979004 Cc1ccnc2c1ccc1c(C)ccnc21 InChI=1S/C14H12N2/c1-9-5-7-15-13-11(9)3-4-12-10(2)6-8-16-14(12)13/h3-8H,1-2H3 JIVLDFFWTQYGSR-UHFFFAOYSA-N 50401348 CHEMBL593442 C-C chemokine receptor type 8 Homo sapiens 501.19 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401348&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search DPT 72792 163350372 CHEMBL593442 DB02586 ZINC00120461 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979005 Cc1cnc2c(ccc3cc(C)cnc23)c1 InChI=1S/C14H12N2/c1-9-5-11-3-4-12-6-10(2)8-16-14(12)13(11)15-7-9/h3-8H,1-2H3 KSACKJIWQPGKMJ-UHFFFAOYSA-N 50401353 CHEMBL2205809 C-C chemokine receptor type 8 Homo sapiens 6309.57 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401353&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 12987698 163350377 CHEMBL2205809 ZINC39365566 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979006 COc1ccnc(c1)-c1cc(OC)ccn1 InChI=1S/C12H12N2O2/c1-15-9-3-5-13-11(7-9)12-8-10(16-2)4-6-14-12/h3-8H,1-2H3 IMEVSAIFJKKDAP-UHFFFAOYSA-N 50401349 CHEMBL2205808 C-C chemokine receptor type 8 Homo sapiens 5011.87 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401349&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 2733927 163350373 CHEMBL2205808 ZINC00403962 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979007 Cc1ccnc(c1)-c1cc(C)ccn1 InChI=1S/C12H12N2/c1-9-3-5-13-11(7-9)12-8-10(2)4-6-14-12/h3-8H,1-2H3 NBPGPQJFYXNFKN-UHFFFAOYSA-N 50401350 CHEMBL101165 C-C chemokine receptor type 8 Homo sapiens 3162.28 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401350&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 14338 163350374 CHEMBL101165 ZINC00120136 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979008 Cc1ccc(nc1)-c1ccc(C)cn1 InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3 PTRATZCAGVBFIQ-UHFFFAOYSA-N 50401351 CHEMBL2205807 C-C chemokine receptor type 8 Homo sapiens 7943.28 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401351&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search EI3 15664 163350375 CHEMBL2205807 ZINC00403335 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979009 Cc1cccc(n1)-c1cccc(C)n1 InChI=1S/C12H12N2/c1-9-5-3-7-11(13-9)12-8-4-6-10(2)14-12/h3-8H,1-2H3 OHJPGUSXUGHOGE-UHFFFAOYSA-N 50401355 CHEMBL2205806 C-C chemokine receptor type 8 Homo sapiens 5011.87 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401355&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 20445 163350379 CHEMBL2205806 ZINC00403297 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979010 c1cnc2c(c1)ccc1cccnc21 InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H DGEZNRSVGBDHLK-UHFFFAOYSA-N 50092158 1,10-phenanthroline::CHEMBL415879::US10669227, Compound 1,10-phenanthroline::US11608309, Compound 1,10-phenanthroline::US9187406, 1,10-phenanthroline::cid_1318 C-C chemokine receptor type 8 Homo sapiens 3981.07 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092158&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search PHN 1318 103990358 44975 CHEMBL415879 DB02365 C00604 ZINC00164363 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50979011 c1ccc(nc1)-c1ccccn1 InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H ROFVEXUMMXZLPA-UHFFFAOYSA-N 50042874 2,2'-Bipyridin::2,2'-bipyridine::2,2'-bipyridyl::2,2'-dipyridine::2,2'-dipyridyl::2-(2-pyridyl)pyridine::CHEMBL39879::US10196346, Bipyridine::alpha,alpha'-bipyridine::alpha,alpha'-bipyridyl::alpha,alpha'-dipyridine::alpha,alpha'-dipyridyl::bpy C-C chemokine receptor type 8 Homo sapiens 39810.72 ChEMBL 10.1021/jm301121j 10.7270/Q2Q81F7S 22957890 Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM University of Copenhagen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042874&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 0BP 1474 103974406 30351 CHEMBL39879 ZINC00105227 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013159 Clc1ccc(cc1)C(=O)N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1 InChI=1S/C29H31ClN2O2/c30-25-11-9-24(10-12-25)28(33)32-19-15-29(16-20-32)13-17-31(18-14-29)22-23-5-4-8-27(21-23)34-26-6-2-1-3-7-26/h1-12,21H,13-20,22H2 RGZNEXHZUKHBNS-UHFFFAOYSA-N 50414957 CHEMBL429436 C-C chemokine receptor type 8 Homo sapiens 19.05 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414957&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457046 163363981 CHEMBL429436 ZINC29133518 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013160 Clc1ccc(cc1)C(=O)N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1 InChI=1S/C29H31ClN2O2/c30-25-12-10-23(11-13-25)28(33)32-20-16-29(17-21-32)14-18-31(19-15-29)22-24-6-4-5-9-27(24)34-26-7-2-1-3-8-26/h1-13H,14-22H2 CSMSBZWRUZAKQB-UHFFFAOYSA-N 50414958 CHEMBL259243 C-C chemokine receptor type 8 Homo sapiens 81.28 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414958&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11273324 163363982 CHEMBL259243 ZINC13981733 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013161 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc(Cl)cc1 InChI=1S/C30H33ClN2O3/c1-35-27-8-4-5-9-28(27)36-26-7-3-2-6-24(26)22-32-18-14-30(15-19-32)16-20-33(21-17-30)29(34)23-10-12-25(31)13-11-23/h2-13H,14-22H2,1H3 FVIRTVGXWNRAMY-UHFFFAOYSA-N 50414959 CHEMBL409224 C-C chemokine receptor type 8 Homo sapiens 34.67 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414959&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457105 163363983 CHEMBL409224 ZINC29133717 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013162 CC(C)COc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncn1 InChI=1S/C25H34N4O2/c1-20(2)18-31-23-6-4-3-5-21(23)17-28-13-8-25(9-14-28)10-15-29(16-11-25)24(30)22-7-12-26-19-27-22/h3-7,12,19-20H,8-11,13-18H2,1-2H3 XHYHAGAWIQDXFU-UHFFFAOYSA-N 50414960 CHEMBL567620 C-C chemokine receptor type 8 Homo sapiens 141.25 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414960&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598769 163363984 CHEMBL567620 ZINC45245518 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013163 CC(C)COc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C26H35N3O2/c1-21(2)20-31-24-6-4-3-5-23(24)19-28-15-9-26(10-16-28)11-17-29(18-12-26)25(30)22-7-13-27-14-8-22/h3-8,13-14,21H,9-12,15-20H2,1-2H3 GLKFHODDQQHCAX-UHFFFAOYSA-N 50414961 CHEMBL567419 C-C chemokine receptor type 8 Homo sapiens 107.15 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414961&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598057 163363985 CHEMBL567419 ZINC45253628 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013164 CC(=C)COc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C26H33N3O2/c1-21(2)20-31-24-6-4-3-5-23(24)19-28-15-9-26(10-16-28)11-17-29(18-12-26)25(30)22-7-13-27-14-8-22/h3-8,13-14H,1,9-12,15-20H2,2H3 DHSWMQRDIKTONS-UHFFFAOYSA-N 50414962 CHEMBL566759 C-C chemokine receptor type 8 Homo sapiens 70.79 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414962&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598819 163363986 CHEMBL566759 ZINC45253324 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013165 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C29H33N3O3/c1-34-26-8-4-5-9-27(26)35-25-7-3-2-6-24(25)22-31-18-12-29(13-19-31)14-20-32(21-15-29)28(33)23-10-16-30-17-11-23/h2-11,16-17H,12-15,18-22H2,1H3 WWTXVMIWFBVHQA-UHFFFAOYSA-N 50414964 CHEMBL271128 C-C chemokine receptor type 8 Homo sapiens 11.48 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414964&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44457090 163363988 CHEMBL271128 ZINC29133668 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013166 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1cc[n+]([O-])cc1 InChI=1S/C29H33N3O4/c1-35-26-8-4-5-9-27(26)36-25-7-3-2-6-24(25)22-30-18-12-29(13-19-30)14-20-31(21-15-29)28(33)23-10-16-32(34)17-11-23/h2-11,16-17H,12-15,18-22H2,1H3 DVQXAHGZSWJSQT-UHFFFAOYSA-N 50414965 CHEMBL270971 C-C chemokine receptor type 8 Homo sapiens 114.82 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414965&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11950828 163363989 CHEMBL270971 ZINC29133611 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013167 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncn1 InChI=1S/C28H32N4O3/c1-34-25-8-4-5-9-26(25)35-24-7-3-2-6-22(24)20-31-16-11-28(12-17-31)13-18-32(19-14-28)27(33)23-10-15-29-21-30-23/h2-10,15,21H,11-14,16-20H2,1H3 GMCICJZIANWTML-UHFFFAOYSA-N 50414966 CHEMBL573216 C-C chemokine receptor type 8 Homo sapiens 14.79 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414966&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598821 163363990 CHEMBL573216 ZINC45285526 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013168 O=C(N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1)c1ccncc1 InChI=1S/C28H31N3O2/c32-27(24-9-15-29-16-10-24)31-19-13-28(14-20-31)11-17-30(18-12-28)22-23-5-4-8-26(21-23)33-25-6-2-1-3-7-25/h1-10,15-16,21H,11-14,17-20,22H2 KHWFDRKDQCSBEW-UHFFFAOYSA-N 50414967 CHEMBL271801 C-C chemokine receptor type 8 Homo sapiens 17.38 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414967&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44456993 163363991 CHEMBL271801 ZINC29133289 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013169 O=C(N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1)c1ccncn1 InChI=1S/C27H30N4O2/c32-26(25-9-14-28-21-29-25)31-17-12-27(13-18-31)10-15-30(16-11-27)20-22-5-4-8-24(19-22)33-23-6-2-1-3-7-23/h1-9,14,19,21H,10-13,15-18,20H2 GDZWYFZOGVMUEB-UHFFFAOYSA-N 50414968 CHEMBL410885 C-C chemokine receptor type 8 Homo sapiens 27.54 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414968&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44456948 163363992 CHEMBL410885 ZINC29133131 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013170 COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccncn2)c1 InChI=1S/C28H32N4O3/c1-34-25-7-2-3-8-26(25)35-23-6-4-5-22(19-23)20-31-15-10-28(11-16-31)12-17-32(18-13-28)27(33)24-9-14-29-21-30-24/h2-9,14,19,21H,10-13,15-18,20H2,1H3 DDUAZQDCAKMWPF-UHFFFAOYSA-N 50414983 CHEMBL574655 C-C chemokine receptor type 8 Homo sapiens 4.9 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414983&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598058 163364007 CHEMBL574655 ZINC45287152 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013171 COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2cc[n+]([O-])cc2)c1 InChI=1S/C29H33N3O4/c1-35-26-7-2-3-8-27(26)36-25-6-4-5-23(21-25)22-30-17-11-29(12-18-30)13-19-31(20-14-29)28(33)24-9-15-32(34)16-10-24/h2-10,15-16,21H,11-14,17-20,22H2,1H3 UEDWHHXUOBFTMS-UHFFFAOYSA-N 50414969 CHEMBL272022 C-C chemokine receptor type 8 Homo sapiens 32.36 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414969&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11951000 163363993 CHEMBL272022 ZINC29133063 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013172 O=C(N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1)c1ccncn1 InChI=1S/C27H30N4O2/c32-26(24-10-15-28-21-29-24)31-18-13-27(14-19-31)11-16-30(17-12-27)20-22-6-4-5-9-25(22)33-23-7-2-1-3-8-23/h1-10,15,21H,11-14,16-20H2 XYXAYUQJAMPEPZ-UHFFFAOYSA-N 50414984 CHEMBL566974 C-C chemokine receptor type 8 Homo sapiens 141.25 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414984&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598059 163364008 CHEMBL566974 ZINC45245498 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013173 COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc[nH]c1=O InChI=1S/C29H33N3O4/c1-35-25-10-4-5-11-26(25)36-24-9-3-2-7-22(24)21-31-17-12-29(13-18-31)14-19-32(20-15-29)28(34)23-8-6-16-30-27(23)33/h2-11,16H,12-15,17-21H2,1H3,(H,30,33) AQTZHUHBIRXOHR-UHFFFAOYSA-N 50414970 CHEMBL583843 C-C chemokine receptor type 8 Homo sapiens 54.95 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414970&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 11965686 163363994 CHEMBL583843 ZINC43132640 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013174 CC1(C)CCc2cc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncn3)ccc2O1 InChI=1S/C26H34N4O2/c1-25(2)7-5-21-17-20(3-4-23(21)32-25)18-29-13-8-26(9-14-29)10-15-30(16-11-26)24(31)22-6-12-27-19-28-22/h3-4,6,12,17,19H,5,7-11,13-16,18H2,1-2H3 NEHPVKVKVDQPOY-UHFFFAOYSA-N 50414985 CHEMBL568503 C-C chemokine receptor type 8 Homo sapiens 1819.7 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414985&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598060 163364009 CHEMBL568503 ZINC45257130 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013175 CC1(C)CCc2cc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccc(N)cn3)ccc2O1 InChI=1S/C27H36N4O2/c1-26(2)8-7-21-17-20(3-6-24(21)33-26)19-30-13-9-27(10-14-30)11-15-31(16-12-27)25(32)23-5-4-22(28)18-29-23/h3-6,17-18H,7-16,19,28H2,1-2H3 NQHYTSQZQHHSNR-UHFFFAOYSA-N 50414971 CHEMBL567202 C-C chemokine receptor type 8 Homo sapiens 95.5 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414971&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598061 163363995 CHEMBL567202 ZINC45245869 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013176 CC1Cc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncc3)c2O1 InChI=1S/C25H31N3O2/c1-19-17-21-3-2-4-22(23(21)30-19)18-27-13-7-25(8-14-27)9-15-28(16-10-25)24(29)20-5-11-26-12-6-20/h2-6,11-12,19H,7-10,13-18H2,1H3 JQIOFPJNEBMYKB-UHFFFAOYSA-N 50414972 CHEMBL568296 C-C chemokine receptor type 8 Homo sapiens 128.82 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414972&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16065425 163363996 CHEMBL568296 ZINC34984685 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013177 O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1 InChI=1S/C24H29N3O2/c28-23(20-4-11-25-12-5-20)27-15-9-24(10-16-27)7-13-26(14-8-24)18-21-3-1-2-19-6-17-29-22(19)21/h1-5,11-12H,6-10,13-18H2 IZCXWLUHLXSGCA-UHFFFAOYSA-N 50414973 CHEMBL572537 C-C chemokine receptor type 8 Homo sapiens 1479.11 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414973&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16065428 163363997 CHEMBL572537 ZINC34984690 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013178 CC1(C)Oc2c(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccnc(N)c3)cccc2C=C1 InChI=1S/C27H34N4O2/c1-26(2)8-6-20-4-3-5-22(24(20)33-26)19-30-14-9-27(10-15-30)11-16-31(17-12-27)25(32)21-7-13-29-23(28)18-21/h3-8,13,18H,9-12,14-17,19H2,1-2H3,(H2,28,29) QCIHJSOOSHZRET-UHFFFAOYSA-N 50414986 CHEMBL568522 C-C chemokine receptor type 8 Homo sapiens 5.62 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414986&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598062 163364010 CHEMBL568522 ZINC45260392 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013179 CC1(C)Cc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccc(N)cn3)c2O1 InChI=1S/C26H34N4O2/c1-25(2)16-19-4-3-5-20(23(19)32-25)18-29-12-8-26(9-13-29)10-14-30(15-11-26)24(31)22-7-6-21(27)17-28-22/h3-7,17H,8-16,18,27H2,1-2H3 CVDJZICOCOGFGC-UHFFFAOYSA-N 50414974 CHEMBL568523 C-C chemokine receptor type 8 Homo sapiens 2.63 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414974&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16064872 163363998 CHEMBL568523 ZINC34984142 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013180 CC1(C)Oc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccnc(N)c3)c2O1 InChI=1S/C25H32N4O3/c1-24(2)31-20-5-3-4-19(22(20)32-24)17-28-12-7-25(8-13-28)9-14-29(15-10-25)23(30)18-6-11-27-21(26)16-18/h3-6,11,16H,7-10,12-15,17H2,1-2H3,(H2,26,27) CSPRWLXCNMAWKC-UHFFFAOYSA-N 50414975 CHEMBL584087 C-C chemokine receptor type 8 Homo sapiens 6.61 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414975&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16065704 163363999 CHEMBL584087 ZINC34984929 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013181 CC1(C)Cc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ncccc3N)c2O1 InChI=1S/C26H34N4O2/c1-25(2)17-19-5-3-6-20(23(19)32-25)18-29-13-8-26(9-14-29)10-15-30(16-11-26)24(31)22-21(27)7-4-12-28-22/h3-7,12H,8-11,13-18,27H2,1-2H3 QYNQDAFXODBCAX-UHFFFAOYSA-N 50414976 CHEMBL566324 C-C chemokine receptor type 8 Homo sapiens 22.39 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414976&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 45483913 163364000 CHEMBL566324 ZINC45246069 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013182 CC1(C)Cc2c(O1)cccc2CN1CCC2(CC1)CCN(CC2)C(=O)c1ccnc(N)c1 InChI=1S/C26H34N4O2/c1-25(2)17-21-20(4-3-5-22(21)32-25)18-29-12-7-26(8-13-29)9-14-30(15-10-26)24(31)19-6-11-28-23(27)16-19/h3-6,11,16H,7-10,12-15,17-18H2,1-2H3,(H2,27,28) RWGFKKGYHOTXRZ-UHFFFAOYSA-N 50414977 CHEMBL567627 C-C chemokine receptor type 8 Homo sapiens 22.39 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414977&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598121 163364001 CHEMBL567627 ZINC45245622 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013183 CC1(C)Cc2c(O1)cccc2CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc(N)cn1 InChI=1S/C26H34N4O2/c1-25(2)16-21-19(4-3-5-23(21)32-25)18-29-12-8-26(9-13-29)10-14-30(15-11-26)24(31)22-7-6-20(27)17-28-22/h3-7,17H,8-16,18,27H2,1-2H3 WIGFMKMFRGRSDE-UHFFFAOYSA-N 50414978 CHEMBL566543 C-C chemokine receptor type 8 Homo sapiens 8.13 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414978&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16065569 163364002 CHEMBL566543 ZINC34984816 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013184 CC1(C)Cc2c(O1)cccc2CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C26H33N3O2/c1-25(2)18-22-21(4-3-5-23(22)31-25)19-28-14-8-26(9-15-28)10-16-29(17-11-26)24(30)20-6-12-27-13-7-20/h3-7,12-13H,8-11,14-19H2,1-2H3 IRHNBISUJFEBRF-UHFFFAOYSA-N 50414979 CHEMBL583621 C-C chemokine receptor type 8 Homo sapiens 30.9 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414979&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16065567 163364003 CHEMBL583621 ZINC34984814 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013185 CC(C)(C)C1(C)Cc2c(O1)cccc2CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc(N)cn1 InChI=1S/C29H40N4O2/c1-27(2,3)28(4)18-23-21(6-5-7-25(23)35-28)20-32-14-10-29(11-15-32)12-16-33(17-13-29)26(34)24-9-8-22(30)19-31-24/h5-9,19H,10-18,20,30H2,1-4H3 FURLYCMNDIFIIK-UHFFFAOYSA-N 50414980 CHEMBL568294 C-C chemokine receptor type 8 Homo sapiens 2.82 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414980&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 45483880 163364004 CHEMBL568294 ZINC45258504 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013186 CCCC1(CC)Cc2c(O1)cccc2CN1CCC2(CC1)CCN(CC2)C(=O)c1ccc(N)cn1 InChI=1S/C29H40N4O2/c1-3-10-29(4-2)19-24-22(6-5-7-26(24)35-29)21-32-15-11-28(12-16-32)13-17-33(18-14-28)27(34)25-9-8-23(30)20-31-25/h5-9,20H,3-4,10-19,21,30H2,1-2H3 KXLSNWXEEUBBQQ-UHFFFAOYSA-N 50414981 CHEMBL567417 C-C chemokine receptor type 8 Homo sapiens 2.4 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414981&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 45483901 163364005 CHEMBL567417 ZINC45253624 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013187 CC1(C)Oc2c(cccc2CN2CCC3(CC2)CCN(CC3)C(=O)c2ccc(N)cn2)C1(F)F InChI=1S/C26H32F2N4O2/c1-24(2)26(27,28)20-5-3-4-18(22(20)34-24)17-31-12-8-25(9-13-31)10-14-32(15-11-25)23(33)21-7-6-19(29)16-30-21/h3-7,16H,8-15,17,29H2,1-2H3 BWHTVWPCTVOLNL-UHFFFAOYSA-N 50414982 CHEMBL579072 C-C chemokine receptor type 8 Homo sapiens 2.63 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414982&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598124 163364006 CHEMBL579072 ZINC45302236 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51013197 FC(F)C(F)(F)Oc1ccccc1CN1CCC2(CC1)CCN(CC2)C(=O)c1ccncc1 InChI=1S/C24H27F4N3O2/c25-22(26)24(27,28)33-20-4-2-1-3-19(20)17-30-13-7-23(8-14-30)9-15-31(16-10-23)21(32)18-5-11-29-12-6-18/h1-6,11-12,22H,7-10,13-17H2 ZQYTURKIACTXPU-UHFFFAOYSA-N 50414963 CHEMBL583212 C-C chemokine receptor type 8 Homo sapiens 524.81 ChEMBL 10.1021/jm900713y 10.7270/Q2TH8NZP 19954248 Shamovsky, I; de Graaf, C; Alderin, L; Bengtsson, M; Bladh, H; Borjesson, L; Connolly, S; Dyke, HJ; van den Heuvel, M; Johansson, H; Josefsson, BG; Kristoffersson, A; Linnanen, T; Lisius, A; Mannikko, R; Norden, B; Price, S; Ripa, L; Rognan, D; Rosendahl, A; Skrinjar, M; Urbahns, K AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50414963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50414963&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 44598820 163363987 CHEMBL583212 ZINC45318879 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50804279 CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@@]1(C)CCOC1 InChI=1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,18+/m1/s1 DNXKACKCTLURQN-ACJLOTCBSA-N 50255479 CHEMBL4067429 C-C chemokine receptor type 8 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b01854 10.7270/Q2959M1F 29406702 Lu, H; Yang, T; Xu, Z; Lin, X; Ding, Q; Zhang, Y; Cai, X; Dong, K; Gong, S; Zhang, W; Patel, M; Copley, RCB; Xiang, J; Guan, X; Wren, P; Ren, F GSK Pharmaceuticals R & D http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255479&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 100951623 402360319 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 50803696 CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@@]1(C)CCOC1 InChI=1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,18+/m1/s1 DNXKACKCTLURQN-ACJLOTCBSA-N 50255479 CHEMBL4067429 C-C chemokine receptor type 8 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b01854 10.7270/Q2959M1F 29406702 Lu, H; Yang, T; Xu, Z; Lin, X; Ding, Q; Zhang, Y; Cai, X; Dong, K; Gong, S; Zhang, W; Patel, M; Copley, RCB; Xiang, J; Guan, X; Wren, P; Ren, F GSK Pharmaceuticals R & D http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255479&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 100951623 402360319 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51191753 COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12 InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28) YTEVTHHGQMUPHC-UHFFFAOYSA-N 50380880 CHEMBL2018969 C-C chemokine receptor type 8 Homo sapiens <10000 ChEMBL 10.1021/jm301572h 10.7270/Q26W9F07 23409871 Procopiou, PA; Barrett, JW; Barton, NP; Begg, M; Clapham, D; Copley, RC; Ford, AJ; Graves, RH; Hall, DA; Hancock, AP; Hill, AP; Hobbs, H; Hodgson, ST; Jumeaux, C; Lacroix, YM; Miah, AH; Morriss, KM; Needham, D; Sheriff, EB; Slack, RJ; Smith, CE; Sollis, SL; Staton, H GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380880&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 46861584 160859963 CHEMBL2018969 ZINC84618892 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51249566 CC[C@@]12CCCN(C#N)[C@@H]1c1c(CCNC(=O)c3ccc(Br)cc3)c3ccccc3n1C(=C2)C(=O)OC InChI=1S/C29H29BrN4O3/c1-3-29-14-6-16-33(18-31)26(29)25-22(13-15-32-27(35)19-9-11-20(30)12-10-19)21-7-4-5-8-23(21)34(25)24(17-29)28(36)37-2/h4-5,7-12,17,26H,3,6,13-16H2,1-2H3,(H,32,35)/t26-,29+/m1/s1 IUXSPRUXYTWDEG-UHSQPCAPSA-N 50511108 CHEMBL4558185 C-C chemokine receptor type 8 Homo sapiens 5200 ChEMBL 10.1021/acs.jmedchem.9b01924 10.7270/Q2J969PN 31913038 Norwood, VM; Brice-Tutt, AC; Eans, SO; Stacy, HM; Shi, G; Ratnayake, R; Rocca, JR; Abboud, KA; Li, C; Luesch, H; McLaughlin, JP; Huigens, RW University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50511108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50511108&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 155557362 440719690 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51385884 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN(C#N)[C@@H](C[C@H]12)c1[nH]c2ccccc2c1CCn1cc(nn1)-c1cccc(Cl)c1 50559936 CHEMBL4744046 C-C chemokine receptor type 8 Homo sapiens 7290 ChEMBL 10.1016/j.bmc.2020.115546 10.7270/Q2F193D1 32616180 Paciaroni, NG; Norwood, VM; Ratnayake, R; Luesch, H; Huigens, RW University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50559936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50559936&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 132072454 461830328 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573048 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H31N3O3S/c1-16-7-5-6-8-21(16)23(27)24-22-10-9-20(15-17(22)2)30(28,29)25-18(3)19-11-13-26(4)14-12-19/h5-10,15,18-19,25H,11-14H2,1-4H3,(H,24,27)/t18-/m1/s1 PDAOEKSLYKFTKF-GOSISDBHSA-N 50632674 CHEMBL5407071 C-C chemokine receptor type 8 Homo sapiens 24 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632674&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573049 CCCN1CCN(CC1)c1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)ccc1OC InChI=1S/C32H36N4O4S/c1-4-17-35-18-20-36(21-19-35)29-22-24(13-15-30(29)40-3)34-41(38,39)31-16-14-28(26-11-7-8-12-27(26)31)33-32(37)25-10-6-5-9-23(25)2/h5-16,22,34H,4,17-21H2,1-3H3,(H,33,37) RKLYMSWVGGEUKH-UHFFFAOYSA-N 50632675 CHEMBL5405169 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632675&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573050 CCCN1CCN(CC1)c1ccc(OC)c(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)c1 InChI=1S/C32H36N4O4S/c1-4-17-35-18-20-36(21-19-35)24-13-15-30(40-3)29(22-24)34-41(38,39)31-16-14-28(26-11-7-8-12-27(26)31)33-32(37)25-10-6-5-9-23(25)2/h5-16,22,34H,4,17-21H2,1-3H3,(H,33,37) DBCSRXRQIONWJD-UHFFFAOYSA-N 50632676 CHEMBL5420573 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632676&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573051 CCCN1CCN(CC1)c1cccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)c1C InChI=1S/C32H36N4O3S/c1-4-18-35-19-21-36(22-20-35)30-15-9-14-28(24(30)3)34-40(38,39)31-17-16-29(26-12-7-8-13-27(26)31)33-32(37)25-11-6-5-10-23(25)2/h5-17,34H,4,18-22H2,1-3H3,(H,33,37) JDANLNNEJAOTKB-UHFFFAOYSA-N 50632677 CHEMBL5422913 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632677&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573052 CCCN1CCN(CC1)c1ccc(C)c(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)c1 InChI=1S/C32H36N4O3S/c1-4-17-35-18-20-36(21-19-35)25-14-13-24(3)30(22-25)34-40(38,39)31-16-15-29(27-11-7-8-12-28(27)31)33-32(37)26-10-6-5-9-23(26)2/h5-16,22,34H,4,17-21H2,1-3H3,(H,33,37) WCZLWYHDROABHC-UHFFFAOYSA-N 50632678 CHEMBL5434367 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632678&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573053 CCCN1CCCN(CC1)c1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)ccc1OC InChI=1S/C33H38N4O4S/c1-4-18-36-19-9-20-37(22-21-36)30-23-25(14-16-31(30)41-3)35-42(39,40)32-17-15-29(27-12-7-8-13-28(27)32)34-33(38)26-11-6-5-10-24(26)2/h5-8,10-17,23,35H,4,9,18-22H2,1-3H3,(H,34,38) OVPXDDIIODUZHA-UHFFFAOYSA-N 50632679 CHEMBL5420476 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632679&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573054 CN(C)CCn1ccc2cccc(NS(=O)(=O)c3ccc(NC(=O)c4ccccc4C)c4ccccc34)c12 InChI=1S/C30H30N4O3S/c1-21-9-4-5-11-23(21)30(35)31-26-15-16-28(25-13-7-6-12-24(25)26)38(36,37)32-27-14-8-10-22-17-18-34(29(22)27)20-19-33(2)3/h4-18,32H,19-20H2,1-3H3,(H,31,35) WTBTYGXICUROOW-UHFFFAOYSA-N 50632680 CHEMBL5399791 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632680&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573055 CN(C)CCN1C(=O)COc2cccc(NS(=O)(=O)c3ccc(NC(=O)c4ccccc4C)c4ccccc34)c12 InChI=1S/C30H30N4O5S/c1-20-9-4-5-10-21(20)30(36)31-24-15-16-27(23-12-7-6-11-22(23)24)40(37,38)32-25-13-8-14-26-29(25)34(18-17-33(2)3)28(35)19-39-26/h4-16,32H,17-19H2,1-3H3,(H,31,36) FZUOKWOLJGXZRP-UHFFFAOYSA-N 50632681 CHEMBL5417132 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632681&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573056 CCCC(=O)N1CCC(CC1)C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C28H31N3O5S/c1-3-8-26(32)31-17-15-20(16-18-31)27(33)30-37(35,36)25-14-13-24(22-11-6-7-12-23(22)25)29-28(34)21-10-5-4-9-19(21)2/h4-7,9-14,20H,3,8,15-18H2,1-2H3,(H,29,34)(H,30,33) MWEPRMWYSQSNCG-UHFFFAOYSA-N 50632682 CHEMBL5406553 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632682&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573057 CCCC(=O)N1CC[C@H](C1)C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C27H29N3O5S/c1-3-8-25(31)30-16-15-19(17-30)26(32)29-36(34,35)24-14-13-23(21-11-6-7-12-22(21)24)28-27(33)20-10-5-4-9-18(20)2/h4-7,9-14,19H,3,8,15-17H2,1-2H3,(H,28,33)(H,29,32)/t19-/m1/s1 LQMBILFVRRIRRJ-LJQANCHMSA-N 50632683 CHEMBL5423271 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632683&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573058 CCCC(=O)N1CC(C1)C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C26H27N3O5S/c1-3-8-24(30)29-15-18(16-29)25(31)28-35(33,34)23-14-13-22(20-11-6-7-12-21(20)23)27-26(32)19-10-5-4-9-17(19)2/h4-7,9-14,18H,3,8,15-16H2,1-2H3,(H,27,32)(H,28,31) XIGXKUOCBFPDGG-UHFFFAOYSA-N 50632684 CHEMBL5425376 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632684&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573059 CCCC(=O)N1CCCC(C1)C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C28H31N3O5S/c1-3-9-26(32)31-17-8-11-20(18-31)27(33)30-37(35,36)25-16-15-24(22-13-6-7-14-23(22)25)29-28(34)21-12-5-4-10-19(21)2/h4-7,10,12-16,20H,3,8-9,11,17-18H2,1-2H3,(H,29,34)(H,30,33) PWCRLOZAYZXJKB-UHFFFAOYSA-N 50632685 CHEMBL5418858 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632685&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573060 CCCC(=O)N1CCCC(CNS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)C1 InChI=1S/C28H33N3O4S/c1-3-9-27(32)31-17-8-11-21(19-31)18-29-36(34,35)26-16-15-25(23-13-6-7-14-24(23)26)30-28(33)22-12-5-4-10-20(22)2/h4-7,10,12-16,21,29H,3,8-9,11,17-19H2,1-2H3,(H,30,33) MBHLMALVPHBJJZ-UHFFFAOYSA-N 50632686 CHEMBL5437965 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632686&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573061 CCCC(=O)N1CCCC(C1)C(C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C29H35N3O4S/c1-4-10-28(33)32-18-9-12-22(19-32)21(3)31-37(35,36)27-17-16-26(24-14-7-8-15-25(24)27)30-29(34)23-13-6-5-11-20(23)2/h5-8,11,13-17,21-22,31H,4,9-10,12,18-19H2,1-3H3,(H,30,34) RHECULCAGFUPGT-UHFFFAOYSA-N 50632687 CHEMBL5415778 C-C chemokine receptor type 8 Homo sapiens 500 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632687&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573062 CC(NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCCNC1 InChI=1S/C25H29N3O3S/c1-17-8-3-4-10-20(17)25(29)27-23-13-14-24(22-12-6-5-11-21(22)23)32(30,31)28-18(2)19-9-7-15-26-16-19/h3-6,8,10-14,18-19,26,28H,7,9,15-16H2,1-2H3,(H,27,29) AOAMSPIUGBXLIS-UHFFFAOYSA-N 50632688 CHEMBL5432566 C-C chemokine receptor type 8 Homo sapiens 112 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632688&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573063 CC(NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCCCN1 InChI=1S/C25H29N3O3S/c1-17-9-3-4-10-19(17)25(29)27-23-14-15-24(21-12-6-5-11-20(21)23)32(30,31)28-18(2)22-13-7-8-16-26-22/h3-6,9-12,14-15,18,22,26,28H,7-8,13,16H2,1-2H3,(H,27,29) FPUMELQVSQNXRM-UHFFFAOYSA-N 50632689 CHEMBL5409668 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632689&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573064 CC(NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCNCC1 InChI=1S/C25H29N3O3S/c1-17-7-3-4-8-20(17)25(29)27-23-11-12-24(22-10-6-5-9-21(22)23)32(30,31)28-18(2)19-13-15-26-16-14-19/h3-12,18-19,26,28H,13-16H2,1-2H3,(H,27,29) FZGNNJULCOVMFP-UHFFFAOYSA-N 50632690 CHEMBL5399315 C-C chemokine receptor type 8 Homo sapiens 29 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632690&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573065 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C12CCN(CC1)CC2 InChI=1S/C27H31N3O3S/c1-19-7-3-4-8-21(19)26(31)28-24-11-12-25(23-10-6-5-9-22(23)24)34(32,33)29-20(2)27-13-16-30(17-14-27)18-15-27/h3-12,20,29H,13-18H2,1-2H3,(H,28,31)/t20-/m1/s1 HQAVYRTVKXSYHH-HXUWFJFHSA-N 50632691 CHEMBL5424675 C-C chemokine receptor type 8 Homo sapiens 303 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632691&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573066 CC(NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCNC1 InChI=1S/C24H27N3O3S/c1-16-7-3-4-8-19(16)24(28)26-22-11-12-23(21-10-6-5-9-20(21)22)31(29,30)27-17(2)18-13-14-25-15-18/h3-12,17-18,25,27H,13-15H2,1-2H3,(H,26,28) HPEBWNUVJZJWMI-UHFFFAOYSA-N 50632692 CHEMBL5395905 C-C chemokine receptor type 8 Homo sapiens 85 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632692&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573067 C[C@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCNCC1 InChI=1S/C25H29N3O3S/c1-17-7-3-4-8-20(17)25(29)27-23-11-12-24(22-10-6-5-9-21(22)23)32(30,31)28-18(2)19-13-15-26-16-14-19/h3-12,18-19,26,28H,13-16H2,1-2H3,(H,27,29)/t18-/m0/s1 FZGNNJULCOVMFP-SFHVURJKSA-N 50632693 CHEMBL5418685 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632693&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573068 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCNCC1 InChI=1S/C25H29N3O3S/c1-17-7-3-4-8-20(17)25(29)27-23-11-12-24(22-10-6-5-9-21(22)23)32(30,31)28-18(2)19-13-15-26-16-14-19/h3-12,18-19,26,28H,13-16H2,1-2H3,(H,27,29)/t18-/m1/s1 FZGNNJULCOVMFP-GOSISDBHSA-N 50632694 CHEMBL5400852 C-C chemokine receptor type 8 Homo sapiens 14 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632694&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573069 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12)C1CCN(C)CC1 InChI=1S/C26H31N3O3S/c1-18-8-4-5-9-21(18)26(30)27-24-12-13-25(23-11-7-6-10-22(23)24)33(31,32)28-19(2)20-14-16-29(3)17-15-20/h4-13,19-20,28H,14-17H2,1-3H3,(H,27,30)/t19-/m1/s1 QPUSPMLCFPBBAJ-LJQANCHMSA-N 50632695 CHEMBL5404620 C-C chemokine receptor type 8 Homo sapiens 1.2 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632695&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573070 CCc1cc(ccc1NC(=O)c1ccccc1C)S(=O)(=O)N[C@H](C)C1CCN(C)CC1 InChI=1S/C24H33N3O3S/c1-5-19-16-21(31(29,30)26-18(3)20-12-14-27(4)15-13-20)10-11-23(19)25-24(28)22-9-7-6-8-17(22)2/h6-11,16,18,20,26H,5,12-15H2,1-4H3,(H,25,28)/t18-/m1/s1 ZAWRXMPUGMBIEH-GOSISDBHSA-N 50632696 CHEMBL5400674 C-C chemokine receptor type 8 Homo sapiens 13 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632696&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573071 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(c1)C#N)C1CCN(C)CC1 InChI=1S/C23H28N4O3S/c1-16-6-4-5-7-21(16)23(28)25-22-9-8-20(14-19(22)15-24)31(29,30)26-17(2)18-10-12-27(3)13-11-18/h4-9,14,17-18,26H,10-13H2,1-3H3,(H,25,28)/t17-/m1/s1 VRGCCZKLCYARQU-QGZVFWFLSA-N 50632697 CHEMBL5437244 C-C chemokine receptor type 8 Homo sapiens 33 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632697&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573072 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(Cl)c1)C1CCN(C)CC1 InChI=1S/C22H28ClN3O3S/c1-15-6-4-5-7-19(15)22(27)24-21-9-8-18(14-20(21)23)30(28,29)25-16(2)17-10-12-26(3)13-11-17/h4-9,14,16-17,25H,10-13H2,1-3H3,(H,24,27)/t16-/m1/s1 WVHFHVWRXLSXJR-MRXNPFEDSA-N 50632698 CHEMBL5400080 C-C chemokine receptor type 8 Homo sapiens 27 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632698&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573073 C[C@@H](NS(=O)(=O)c1cc(C)c(NC(=O)c2ccccc2C)cc1F)C1CCN(C)CC1 InChI=1S/C23H30FN3O3S/c1-15-7-5-6-8-19(15)23(28)25-21-14-20(24)22(13-16(21)2)31(29,30)26-17(3)18-9-11-27(4)12-10-18/h5-8,13-14,17-18,26H,9-12H2,1-4H3,(H,25,28)/t17-/m1/s1 JJGXKVOJJIZPOS-QGZVFWFLSA-N 50632699 CHEMBL5404280 C-C chemokine receptor type 8 Homo sapiens 6.0 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632699&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573074 C[C@@H](NS(=O)(=O)c1cc(C)c(NC(=O)c2ccccc2C)cc1C)C1CCN(C)CC1 InChI=1S/C24H33N3O3S/c1-16-8-6-7-9-21(16)24(28)25-22-14-18(3)23(15-17(22)2)31(29,30)26-19(4)20-10-12-27(5)13-11-20/h6-9,14-15,19-20,26H,10-13H2,1-5H3,(H,25,28)/t19-/m1/s1 ZEITUEUSXWSLTN-LJQANCHMSA-N 50632700 CHEMBL5399936 C-C chemokine receptor type 8 Homo sapiens 4.0 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632700&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573075 C[C@@H](NS(=O)(=O)c1cc(C)c(NC(=O)c2ccccc2C)cc1Cl)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-7-5-6-8-19(15)23(28)25-21-14-20(24)22(13-16(21)2)31(29,30)26-17(3)18-9-11-27(4)12-10-18/h5-8,13-14,17-18,26H,9-12H2,1-4H3,(H,25,28)/t17-/m1/s1 VUSNWNTWQCLKQM-QGZVFWFLSA-N 50632701 CHEMBL5412094 C-C chemokine receptor type 8 Homo sapiens 6.0 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632701&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573076 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1Cl)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-7-5-6-8-19(15)23(28)25-20-9-10-21(22(24)16(20)2)31(29,30)26-17(3)18-11-13-27(4)14-12-18/h5-10,17-18,26H,11-14H2,1-4H3,(H,25,28)/t17-/m1/s1 WJMCYRWWUTXNJY-QGZVFWFLSA-N 50632702 CHEMBL5435573 C-C chemokine receptor type 8 Homo sapiens 158 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632702&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573077 C[C@@H](NS(=O)(=O)c1cc(C)c(NC(=O)c2ccccc2C)c(Cl)c1)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-7-5-6-8-20(15)23(28)25-22-16(2)13-19(14-21(22)24)31(29,30)26-17(3)18-9-11-27(4)12-10-18/h5-8,13-14,17-18,26H,9-12H2,1-4H3,(H,25,28)/t17-/m1/s1 ZEDJVOTUUKLHRW-QGZVFWFLSA-N 50632703 CHEMBL5424187 C-C chemokine receptor type 8 Homo sapiens 1.000000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632703&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573078 CC(C)c1ccccc1C(=O)Nc1ccc(cc1C)S(=O)(=O)N[C@H](C)C1CCN(C)CC1 InChI=1S/C25H35N3O3S/c1-17(2)22-8-6-7-9-23(22)25(29)26-24-11-10-21(16-18(24)3)32(30,31)27-19(4)20-12-14-28(5)15-13-20/h6-11,16-17,19-20,27H,12-15H2,1-5H3,(H,26,29)/t19-/m1/s1 SKNMYKJQZYECBI-LJQANCHMSA-N 50632704 CHEMBL5428200 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632704&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573079 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C(F)(F)F)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H28F3N3O3S/c1-15-14-18(33(31,32)28-16(2)17-10-12-29(3)13-11-17)8-9-21(15)27-22(30)19-6-4-5-7-20(19)23(24,25)26/h4-9,14,16-17,28H,10-13H2,1-3H3,(H,27,30)/t16-/m1/s1 LQZBVXGFXOFUTO-MRXNPFEDSA-N 50632705 CHEMBL5397155 C-C chemokine receptor type 8 Homo sapiens 46 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632705&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573080 COc1ccccc1C(=O)Nc1ccc(cc1C)S(=O)(=O)N[C@H](C)C1CCNCC1 InChI=1S/C22H29N3O4S/c1-15-14-18(30(27,28)25-16(2)17-10-12-23-13-11-17)8-9-20(15)24-22(26)19-6-4-5-7-21(19)29-3/h4-9,14,16-17,23,25H,10-13H2,1-3H3,(H,24,26)/t16-/m1/s1 HSRWDJDZWGVKOZ-MRXNPFEDSA-N 50632706 CHEMBL5415309 C-C chemokine receptor type 8 Homo sapiens 735 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632706&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573081 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2cccc(Cl)c2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-14-19(31(29,30)26-17(3)18-10-12-27(4)13-11-18)8-9-22(15)25-23(28)20-6-5-7-21(24)16(20)2/h5-9,14,17-18,26H,10-13H2,1-4H3,(H,25,28)/t17-/m1/s1 BAVBVYZHFALFJB-QGZVFWFLSA-N 50632707 CHEMBL5397693 C-C chemokine receptor type 8 Homo sapiens 1.3 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632707&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573082 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-13-19(24)5-7-21(15)23(28)25-22-8-6-20(14-16(22)2)31(29,30)26-17(3)18-9-11-27(4)12-10-18/h5-8,13-14,17-18,26H,9-12H2,1-4H3,(H,25,28)/t17-/m1/s1 FKQQCQXMXMBPKV-QGZVFWFLSA-N 50632708 CHEMBL5411391 C-C chemokine receptor type 8 Homo sapiens 1.7 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632708&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573083 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2cc(Cl)ccc2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-5-6-19(24)14-21(15)23(28)25-22-8-7-20(13-16(22)2)31(29,30)26-17(3)18-9-11-27(4)12-10-18/h5-8,13-14,17-18,26H,9-12H2,1-4H3,(H,25,28)/t17-/m1/s1 ZJPVBCZDLWQLPE-QGZVFWFLSA-N 50632709 CHEMBL5412884 C-C chemokine receptor type 8 Homo sapiens 1.7 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632709&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573084 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2c(C)cccc2Cl)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H30ClN3O3S/c1-15-6-5-7-20(24)22(15)23(28)25-21-9-8-19(14-16(21)2)31(29,30)26-17(3)18-10-12-27(4)13-11-18/h5-9,14,17-18,26H,10-13H2,1-4H3,(H,25,28)/t17-/m1/s1 BXXLMWYCUIMHKI-QGZVFWFLSA-N 50632710 CHEMBL5402712 C-C chemokine receptor type 8 Homo sapiens 37 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632710&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573085 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)C2CCCCCC2)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H37N3O3S/c1-17-16-21(30(28,29)25-18(2)19-12-14-26(3)15-13-19)10-11-22(17)24-23(27)20-8-6-4-5-7-9-20/h10-11,16,18-20,25H,4-9,12-15H2,1-3H3,(H,24,27)/t18-/m1/s1 YMXGGZBLZCJYIK-GOSISDBHSA-N 50632711 CHEMBL5412408 C-C chemokine receptor type 8 Homo sapiens 28 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632711&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573086 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccsc2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C21H29N3O3S2/c1-14-13-18(5-6-20(14)22-21(25)19-9-12-28-16(19)3)29(26,27)23-15(2)17-7-10-24(4)11-8-17/h5-6,9,12-13,15,17,23H,7-8,10-11H2,1-4H3,(H,22,25)/t15-/m1/s1 WJDOIQXRVHSNCC-OAHLLOKOSA-N 50632712 CHEMBL5410064 C-C chemokine receptor type 8 Homo sapiens 33 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632712&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573087 CCCN1CCC(CC1)[C@@H](C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1 InChI=1S/C25H35N3O3S/c1-5-14-28-15-12-21(13-16-28)20(4)27-32(30,31)22-10-11-24(19(3)17-22)26-25(29)23-9-7-6-8-18(23)2/h6-11,17,20-21,27H,5,12-16H2,1-4H3,(H,26,29)/t20-/m1/s1 KEOXMRLFRBVDBK-HXUWFJFHSA-N 50632713 CHEMBL5434812 C-C chemokine receptor type 8 Homo sapiens 26 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632713&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573088 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(CC1)C1COC1 InChI=1S/C25H33N3O4S/c1-17-6-4-5-7-23(17)25(29)26-24-9-8-22(14-18(24)2)33(30,31)27-19(3)20-10-12-28(13-11-20)21-15-32-16-21/h4-9,14,19-21,27H,10-13,15-16H2,1-3H3,(H,26,29)/t19-/m1/s1 UTXPFZUQJBWFAY-LJQANCHMSA-N 50632714 CHEMBL5438933 C-C chemokine receptor type 8 Homo sapiens 90 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632714&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573089 COCCN1CCC(CC1)[C@@H](C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1 InChI=1S/C25H35N3O4S/c1-18-7-5-6-8-23(18)25(29)26-24-10-9-22(17-19(24)2)33(30,31)27-20(3)21-11-13-28(14-12-21)15-16-32-4/h5-10,17,20-21,27H,11-16H2,1-4H3,(H,26,29)/t20-/m1/s1 VEYIHSISAIXMAC-HXUWFJFHSA-N 50632715 CHEMBL5434069 C-C chemokine receptor type 8 Homo sapiens 79 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632715&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573090 CNC(=O)CN1CCC(CC1)[C@@H](C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1 InChI=1S/C25H34N4O4S/c1-17-7-5-6-8-22(17)25(31)27-23-10-9-21(15-18(23)2)34(32,33)28-19(3)20-11-13-29(14-12-20)16-24(30)26-4/h5-10,15,19-20,28H,11-14,16H2,1-4H3,(H,26,30)(H,27,31)/t19-/m1/s1 MDQLADPSFLENGF-LJQANCHMSA-N 50632716 CHEMBL5394357 C-C chemokine receptor type 8 Homo sapiens 200 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632716&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573091 COC(=O)CN1CCC(CC1)[C@@H](C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1 InChI=1S/C25H33N3O5S/c1-17-7-5-6-8-22(17)25(30)26-23-10-9-21(15-18(23)2)34(31,32)27-19(3)20-11-13-28(14-12-20)16-24(29)33-4/h5-10,15,19-20,27H,11-14,16H2,1-4H3,(H,26,30)/t19-/m1/s1 MHGPRWSOWYEIGO-LJQANCHMSA-N 50632717 CHEMBL5437230 C-C chemokine receptor type 8 Homo sapiens 129 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632717&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573092 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(CC(=O)N(C)C)CC1 InChI=1S/C26H36N4O4S/c1-18-8-6-7-9-23(18)26(32)27-24-11-10-22(16-19(24)2)35(33,34)28-20(3)21-12-14-30(15-13-21)17-25(31)29(4)5/h6-11,16,20-21,28H,12-15,17H2,1-5H3,(H,27,32)/t20-/m1/s1 IDCCWNOEFCYEDL-HXUWFJFHSA-N 50632718 CHEMBL5437085 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632718&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573093 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(CC1)C(C)=O InChI=1S/C24H31N3O4S/c1-16-7-5-6-8-22(16)24(29)25-23-10-9-21(15-17(23)2)32(30,31)26-18(3)20-11-13-27(14-12-20)19(4)28/h5-10,15,18,20,26H,11-14H2,1-4H3,(H,25,29)/t18-/m1/s1 JLKBQMBHZPBMHS-GOSISDBHSA-N 50632719 CHEMBL5398519 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632719&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573094 CN1CCC(CC1)[C@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CC1 InChI=1S/C25H33N3O3S/c1-17-6-4-5-7-22(17)25(29)26-23-11-10-21(16-18(23)2)32(30,31)27-24(19-8-9-19)20-12-14-28(3)15-13-20/h4-7,10-11,16,19-20,24,27H,8-9,12-15H2,1-3H3,(H,26,29)/t24-/m1/s1 NQPBKDNHVUUSGD-XMMPIXPASA-N 50632720 CHEMBL5432261 C-C chemokine receptor type 8 Homo sapiens 85 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632720&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573095 CN1CCC(CNS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c(C)c2)CC1 InChI=1S/C22H29N3O3S/c1-16-6-4-5-7-20(16)22(26)24-21-9-8-19(14-17(21)2)29(27,28)23-15-18-10-12-25(3)13-11-18/h4-9,14,18,23H,10-13,15H2,1-3H3,(H,24,26) UVEZMPCACAEEPC-UHFFFAOYSA-N 50632721 CHEMBL5432453 C-C chemokine receptor type 8 Homo sapiens 251 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632721&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573096 CN1CCC(CC1)[C@@H](CO)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1 InChI=1S/C23H31N3O4S/c1-16-6-4-5-7-20(16)23(28)24-21-9-8-19(14-17(21)2)31(29,30)25-22(15-27)18-10-12-26(3)13-11-18/h4-9,14,18,22,25,27H,10-13,15H2,1-3H3,(H,24,28)/t22-/m1/s1 LLBYYBOITNWZRN-JOCHJYFZSA-N 50632722 CHEMBL5422825 C-C chemokine receptor type 8 Homo sapiens >1000 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632722&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573097 CN1CCN(CC1)C(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c2ccccc12 InChI=1S/C29H35N5O4S/c1-21-7-3-4-8-23(21)28(35)30-26-11-12-27(25-10-6-5-9-24(25)26)39(37,38)31-22-13-15-33(16-14-22)29(36)34-19-17-32(2)18-20-34/h3-12,22,31H,13-20H2,1-2H3,(H,30,35) OHPIAISBTHGTMM-UHFFFAOYSA-N 50203882 2-methyl-N-{4-[1-(4-methyl-piperazine-1-carbonyl)-piperidin-4-ylsulfamoyl]-aphthalen-1-yl}-benzamide::CHEMBL221251 C-C chemokine receptor type 8 Homo sapiens 4.0 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203882&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 16105824 104082840 CHEMBL221251 ZINC28604049 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5 51573098 C[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)c(C)c1)C1CCN(C)CC1 InChI=1S/C23H31N3O3S/c1-16-7-5-6-8-21(16)23(27)24-22-10-9-20(15-17(22)2)30(28,29)25-18(3)19-11-13-26(4)14-12-19/h5-10,15,18-19,25H,11-14H2,1-4H3,(H,24,27)/t18-/m1/s1 PDAOEKSLYKFTKF-GOSISDBHSA-N 50632674 CHEMBL5407071 C-C chemokine receptor type 8 Homo sapiens 34 ChEMBL 10.1021/acs.jmedchem.3c00030 10.7270/Q29P364Q 36988587 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003362&target=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632674&enzyme=C-C+chemokine+receptor+type+8&column=ki&startPg=0&Increment=50&submit=Search 1 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL 8TLM,8KFZ,8KFY,8KFX,8U1U C-C chemokine receptor type 8 CCR8_HUMAN P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5