BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50236279 Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H QYDURWHTEIUTEI-UHFFFAOYSA-N 50129952 2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one::8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one::Amentoflavone::CHEMBL63354::cid_5281600 5-hydroxytryptamine receptor 1D Sus scrofa 4094 ChEMBL 10.1016/s0960-894x(03)00434-7 10.7270/Q2V987F7 12824018 Hanrahan, JR; Chebib, M; Davucheron, NL; Hall, BJ; Johnston, GA University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129952&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5281600 104021411 2631 CHEMBL63354 ZINC03984030 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50784520 O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27) GFORNYWGPFXWHV-UHFFFAOYSA-N 50056947 CHEMBL354210::N-{2-[4-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-ethyl}-benzamide 5-hydroxytryptamine receptor 1D Sus scrofa 6920 ChEMBL 10.1021/jm950759z 10.7270/Q2HT2Q00 9083484 el Ahmad, Y; Laurent, E; Maillet, P; Talab, A; Teste, JF; Dokhan, R; Tran, G; Ollivier, R Cooperation Pharmaceutique Fran�aise http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056947&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9998826 103953077 CHEMBL354210 ZINC22777670 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50784532 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)C1CCCc2ccccc12 InChI=1S/C23H28FN3O/c24-20-10-8-19(9-11-20)23(28)25-12-13-26-14-16-27(17-15-26)22-7-3-5-18-4-1-2-6-21(18)22/h1-2,4,6,8-11,22H,3,5,7,12-17H2,(H,25,28) POZFPYZCVYTCQZ-UHFFFAOYSA-N 50056944 4-Fluoro-N-{2-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL368061 5-hydroxytryptamine receptor 1D Sus scrofa 9770 ChEMBL 10.1021/jm950759z 10.7270/Q2HT2Q00 9083484 el Ahmad, Y; Laurent, E; Maillet, P; Talab, A; Teste, JF; Dokhan, R; Tran, G; Ollivier, R Cooperation Pharmaceutique Fran�aise http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056944&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10474964 103953074 CHEMBL368061 ZINC22938686 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992974 CN(C)CCc1c[nH]c2ccc(Cc3nnn(C)n3)cc12 InChI=1S/C15H20N6/c1-20(2)7-6-12-10-16-14-5-4-11(8-13(12)14)9-15-17-19-21(3)18-15/h4-5,8,10,16H,6-7,9H2,1-3H3 WJXFCBUMAXNPLG-UHFFFAOYSA-N 50407353 CHEMBL298544 5-hydroxytryptamine receptor 1D Sus scrofa 79.43 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407353&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10265905 163356377 CHEMBL298544 ZINC13741372 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992975 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 19.95 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992980 CN(C)CCc1c[nH]c2ccc(cc12)-n1ccnc1C InChI=1S/C16H20N4/c1-12-17-7-9-20(12)14-4-5-16-15(10-14)13(11-18-16)6-8-19(2)3/h4-5,7,9-11,18H,6,8H2,1-3H3 FKWIKKLASAZVLL-UHFFFAOYSA-N 50407361 CHEMBL53764 5-hydroxytryptamine receptor 1D Sus scrofa 7.94 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407361&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10468253 163356385 CHEMBL53764 ZINC13741365 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992985 CN(C)CCc1c[nH]c2ccc(Cc3nncn3C)cc12 InChI=1S/C16H21N5/c1-20(2)7-6-13-10-17-15-5-4-12(8-14(13)15)9-16-19-18-11-21(16)3/h4-5,8,10-11,17H,6-7,9H2,1-3H3 RDZBVPYGBFNXQE-UHFFFAOYSA-N 50407360 CHEMBL54103 5-hydroxytryptamine receptor 1D Sus scrofa 25.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407360&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10379099 163356384 CHEMBL54103 ZINC13741368 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992992 CN(C)CCc1c[nH]c2ccc(Cn3nccn3)cc12 InChI=1S/C15H19N5/c1-19(2)8-5-13-10-16-15-4-3-12(9-14(13)15)11-20-17-6-7-18-20/h3-4,6-7,9-10,16H,5,8,11H2,1-2H3 JAUITRPOMTVVCM-UHFFFAOYSA-N 50407366 CHEMBL298974 5-hydroxytryptamine receptor 1D Sus scrofa 251.19 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407366&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11777873 163356390 CHEMBL298974 ZINC13741361 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992993 CN(C)CCc1c[nH]c2ccc(Cc3ncnn3C)cc12 InChI=1S/C16H21N5/c1-20(2)7-6-13-10-17-15-5-4-12(8-14(13)15)9-16-18-11-19-21(16)3/h4-5,8,10-11,17H,6-7,9H2,1-3H3 NOKSXBRHWWPFDZ-UHFFFAOYSA-N 50407364 CHEMBL52264 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407364&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10379100 163356388 CHEMBL52264 ZINC13741367 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992994 CN(C)CCc1c[nH]c2ccc(Cn3ncnn3)cc12 InChI=1S/C14H18N6/c1-19(2)6-5-12-8-15-14-4-3-11(7-13(12)14)9-20-17-10-16-18-20/h3-4,7-8,10,15H,5-6,9H2,1-2H3 CCDMZRADLKWXMG-UHFFFAOYSA-N 50407359 CHEMBL53467 5-hydroxytryptamine receptor 1D Sus scrofa 39.81 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407359&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10355779 163356383 CHEMBL53467 ZINC13741363 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992998 CN(C)CCc1c[nH]c2ccc(Cn3ccnc3)cc12 InChI=1S/C16H20N4/c1-19(2)7-5-14-10-18-16-4-3-13(9-15(14)16)11-20-8-6-17-12-20/h3-4,6,8-10,12,18H,5,7,11H2,1-2H3 GXDRKMVYBOOCOD-UHFFFAOYSA-N 50407357 CHEMBL52912 5-hydroxytryptamine receptor 1D Sus scrofa 31.62 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407357&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10400849 163356381 CHEMBL52912 ZINC13741358 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992999 CN(C)CCc1c[nH]c2ccc(Cc3nc(N)no3)cc12 InChI=1S/C15H19N5O/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19) GJLPUJJLZFRDTA-UHFFFAOYSA-N 50406758 CHEMBL39243 5-hydroxytryptamine receptor 1D Sus scrofa 25.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406758&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10401691 163355782 CHEMBL39243 ZINC00014701 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993000 NCCc1c[nH]c2ccc(cc12)C(N)=O InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) WKZLNEWVIAGNAW-UHFFFAOYSA-N 21392 3-(2-aminoethyl)-1H-indole-5-carboxamide::5-CT::5-CT,DP::5-carboxamidotryptamine::CHEMBL1256863::CHEMBL18840::[3H]-5-CT::[3H]-5-Carboxamide tryptamine::[3H]-5-Carboxyamidotryptamine::[3H]-5-carboxamidotryptamine 5-hydroxytryptamine receptor 1D Sus scrofa 3.98 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21392&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 8K3 1809 49689464 48292 CHEMBL1256863CHEMBL18840 4 ZINC02539813 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992972 CN(C)CCc1c[nH]c2ccc(Cn3ccnn3)cc12 InChI=1S/C15H19N5/c1-19(2)7-5-13-10-16-15-4-3-12(9-14(13)15)11-20-8-6-17-18-20/h3-4,6,8-10,16H,5,7,11H2,1-2H3 XXDPCAYANNJRPM-UHFFFAOYSA-N 50407362 CHEMBL50837 5-hydroxytryptamine receptor 1D Sus scrofa 50.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407362&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10333305 163356386 CHEMBL50837 ZINC13741360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991541 COc1ccccc1Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 InChI=1S/C20H20N4O2/c1-25-18-5-3-2-4-13(18)11-19-23-20(26-24-19)14-6-7-17-16(10-14)15(8-9-21)12-22-17/h2-7,10,12,22H,8-9,11,21H2,1H3 TWZLBEKNARALNH-UHFFFAOYSA-N 50406752 CHEMBL290080 5-hydroxytryptamine receptor 1D Sus scrofa 16 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406752&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10043339 163355776 CHEMBL290080 ZINC13827463 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991542 NCCc1c[nH]c2ccc(Cc3nc(N)no3)cc12 InChI=1S/C13H15N5O/c14-4-3-9-7-16-11-2-1-8(5-10(9)11)6-12-17-13(15)18-19-12/h1-2,5,7,16H,3-4,6,14H2,(H2,15,18) MQYFTEBJWOVBLK-UHFFFAOYSA-N 50406753 CHEMBL37317 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406753&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11777228 163355777 CHEMBL37317 ZINC00014696 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991543 NCCc1c[nH]c2ccc(CCCc3nc(Cc4ccccc4)no3)cc12 InChI=1S/C22H24N4O/c23-12-11-18-15-24-20-10-9-17(13-19(18)20)7-4-8-22-25-21(26-27-22)14-16-5-2-1-3-6-16/h1-3,5-6,9-10,13,15,24H,4,7-8,11-12,14,23H2 JTBDYCCVUAQYMO-UHFFFAOYSA-N 50406754 CHEMBL37629 5-hydroxytryptamine receptor 1D Sus scrofa 1.6 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406754&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10067088 163355778 CHEMBL37629 ZINC13827461 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991544 CN(C)CCc1c[nH]c2ccc(cc12)-c1ncc(C)o1 InChI=1S/C16H19N3O/c1-11-9-18-16(20-11)12-4-5-15-14(8-12)13(10-17-15)6-7-19(2)3/h4-5,8-10,17H,6-7H2,1-3H3 PVDKAFLWERYGPI-UHFFFAOYSA-N 50406755 CHEMBL38738 5-hydroxytryptamine receptor 1D Sus scrofa 7.9 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406755&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10445796 163355779 CHEMBL38738 ZINC13827494 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991545 CNC(=O)c1ccc(cc1)-c1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 InChI=1S/C20H19N5O2/c1-22-19(26)13-4-2-12(3-5-13)18-24-20(27-25-18)14-6-7-17-16(10-14)15(8-9-21)11-23-17/h2-7,10-11,23H,8-9,21H2,1H3,(H,22,26) UYWUGXNJCFVCQO-UHFFFAOYSA-N 50406756 CHEMBL288880 5-hydroxytryptamine receptor 1D Sus scrofa 0.794328 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406756&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10383965 163355780 CHEMBL288880 ZINC13827471 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991546 CC(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 InChI=1S/C21H21N5O2/c1-13(27)24-17-5-2-14(3-6-17)10-20-25-21(28-26-20)15-4-7-19-18(11-15)16(8-9-22)12-23-19/h2-7,11-12,23H,8-10,22H2,1H3,(H,24,27) MPSISMSDHLPFGV-UHFFFAOYSA-N 50406757 CHEMBL289489 5-hydroxytryptamine receptor 1D Sus scrofa 0.501187 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406757&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9976750 163355781 CHEMBL289489 ZINC13827469 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991547 CN(C)CCc1c[nH]c2ccc(Cc3nc(N)no3)cc12 InChI=1S/C15H19N5O/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19) GJLPUJJLZFRDTA-UHFFFAOYSA-N 50406758 CHEMBL39243 5-hydroxytryptamine receptor 1D Sus scrofa 25 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406758&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10401691 163355782 CHEMBL39243 ZINC00014701 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991548 COc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 InChI=1S/C20H20N4O2/c1-25-16-5-2-13(3-6-16)10-19-23-20(26-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22H,8-10,21H2,1H3 MLCUFIVGGFREKB-UHFFFAOYSA-N 50406759 CHEMBL39331 5-hydroxytryptamine receptor 1D Sus scrofa 0.794328 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406759&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11725312 163355783 CHEMBL39331 ZINC13827467 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991549 CN(C)CCc1c[nH]c2ccc(Cc3nc(no3)-c3ccc(NS(C)(=O)=O)cc3)cc12 InChI=1S/C22H25N5O3S/c1-27(2)11-10-17-14-23-20-9-4-15(12-19(17)20)13-21-24-22(25-30-21)16-5-7-18(8-6-16)26-31(3,28)29/h4-9,12,14,23,26H,10-11,13H2,1-3H3 YIRZCLCPNKBHHA-UHFFFAOYSA-N 50406760 CHEMBL38671 5-hydroxytryptamine receptor 1D Sus scrofa 10 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406760&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10094731 163355784 CHEMBL38671 ZINC13827485 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991551 CN(C)CCc1c[nH]c2ccc(Cc3nc(N)ns3)cc12 InChI=1S/C15H19N5S/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19) BEDGPDAVDXHRMR-UHFFFAOYSA-N 50406762 CHEMBL37462 5-hydroxytryptamine receptor 1D Sus scrofa 2 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406762&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9995045 163355786 CHEMBL37462 ZINC13827497 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991552 CN(C)CCc1c[nH]c2ccc(Cc3nc(Cc4ccc(NS(C)(=O)=O)cc4)no3)cc12 InChI=1S/C23H27N5O3S/c1-28(2)11-10-18-15-24-21-9-6-17(12-20(18)21)14-23-25-22(26-31-23)13-16-4-7-19(8-5-16)27-32(3,29)30/h4-9,12,15,24,27H,10-11,13-14H2,1-3H3 RLRTXTNPUBQHCW-UHFFFAOYSA-N 50406763 CHEMBL39801 5-hydroxytryptamine receptor 1D Sus scrofa 32 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406763&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10434071 163355787 CHEMBL39801 ZINC13827487 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991555 NCCc1c[nH]c2ccc(cc12)-c1nc(no1)C1CC1 InChI=1S/C15H16N4O/c16-6-5-11-8-17-13-4-3-10(7-12(11)13)15-18-14(19-20-15)9-1-2-9/h3-4,7-9,17H,1-2,5-6,16H2 LSUAPUGYEULDQN-UHFFFAOYSA-N 50406761 CHEMBL38482 5-hydroxytryptamine receptor 1D Sus scrofa 7.9 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406761&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11777810 163355785 CHEMBL38482 ZINC13827453 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991556 NCCc1c[nH]c2ccc(CCc3nc(N)no3)cc12 InChI=1S/C14H17N5O/c15-6-5-10-8-17-12-3-1-9(7-11(10)12)2-4-13-18-14(16)19-20-13/h1,3,7-8,17H,2,4-6,15H2,(H2,16,19) DDIZYNRXZAIGGG-UHFFFAOYSA-N 50406765 CHEMBL39111 5-hydroxytryptamine receptor 1D Sus scrofa 10 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406765&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10355831 163355789 CHEMBL39111 ZINC00014702 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991558 CN(C)CCc1c[nH]c2ccc(CCCc3nc(Cc4ccccc4)no3)cc12 InChI=1S/C24H28N4O/c1-28(2)14-13-20-17-25-22-12-11-19(15-21(20)22)9-6-10-24-26-23(27-29-24)16-18-7-4-3-5-8-18/h3-5,7-8,11-12,15,17,25H,6,9-10,13-14,16H2,1-2H3 AGJHDCCFMOEMSS-UHFFFAOYSA-N 50406767 CHEMBL38503 5-hydroxytryptamine receptor 1D Sus scrofa 13 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406767&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11741003 163355791 CHEMBL38503 ZINC13827491 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991559 NCCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccccc2)no1 InChI=1S/C19H18N4O/c20-9-8-15-12-21-17-7-6-14(11-16(15)17)19-22-18(23-24-19)10-13-4-2-1-3-5-13/h1-7,11-12,21H,8-10,20H2 ODYUGGSOAUEDQI-UHFFFAOYSA-N 50406768 CHEMBL288821 5-hydroxytryptamine receptor 1D Sus scrofa 6.3 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406768&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9927016 163355792 CHEMBL288821 ZINC00005092 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991562 Cc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 InChI=1S/C13H14N4O/c1-8-16-13(18-17-8)9-2-3-12-11(6-9)10(4-5-14)7-15-12/h2-3,6-7,15H,4-5,14H2,1H3 BHZAJXDSABBUCR-UHFFFAOYSA-N 50406766 CHEMBL36497 5-hydroxytryptamine receptor 1D Sus scrofa 10 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406766&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10421850 163355790 CHEMBL36497 ZINC00014692 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991565 CN(C)CCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccccc2)no1 InChI=1S/C21H22N4O/c1-25(2)11-10-17-14-22-19-9-8-16(13-18(17)19)21-23-20(24-26-21)12-15-6-4-3-5-7-15/h3-9,13-14,22H,10-12H2,1-2H3 PGGBQIXTFVYDAU-UHFFFAOYSA-N 50406772 CHEMBL290657 5-hydroxytryptamine receptor 1D Sus scrofa 6.3 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406772&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9974915 163355796 CHEMBL290657 ZINC00014693 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991570 CN(C)CCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccc(NS(C)(=O)=O)cc2)no1 InChI=1S/C22H25N5O3S/c1-27(2)11-10-17-14-23-20-9-6-16(13-19(17)20)22-24-21(25-30-22)12-15-4-7-18(8-5-15)26-31(3,28)29/h4-9,13-14,23,26H,10-12H2,1-3H3 DXMSFKTUXGYHFG-UHFFFAOYSA-N 50406774 CHEMBL262652 5-hydroxytryptamine receptor 1D Sus scrofa 1.3 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406774&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9980618 163355798 CHEMBL262652 ZINC13827479 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991574 Cc1noc(Cc2ccc3[nH]cc(CCN)c3c2)n1 InChI=1S/C14H16N4O/c1-9-17-14(19-18-9)7-10-2-3-13-12(6-10)11(4-5-15)8-16-13/h2-3,6,8,16H,4-5,7,15H2,1H3 QSVBXQZVQGKTQZ-UHFFFAOYSA-N 50406770 CHEMBL39712 5-hydroxytryptamine receptor 1D Sus scrofa 32 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406770&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11777180 163355794 CHEMBL39712 ZINC00014694 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991575 NCCc1c[nH]c2ccc(Cc3nc(no3)-c3ccccc3)cc12 InChI=1S/C19H18N4O/c20-9-8-15-12-21-17-7-6-13(10-16(15)17)11-18-22-19(23-24-18)14-4-2-1-3-5-14/h1-7,10,12,21H,8-9,11,20H2 DUCJXOYLGYOOQB-UHFFFAOYSA-N 50406775 CHEMBL290171 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406775&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9996008 163355799 CHEMBL290171 ZINC00014697 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991577 CS(=O)(=O)Nc1ccc(Cc2noc(Cc3ccc4[nH]cc(CCN)c4c3)n2)cc1 InChI=1S/C21H23N5O3S/c1-30(27,28)26-17-5-2-14(3-6-17)11-20-24-21(29-25-20)12-15-4-7-19-18(10-15)16(8-9-22)13-23-19/h2-7,10,13,23,26H,8-9,11-12,22H2,1H3 SORYYVCYBRVPBK-UHFFFAOYSA-N 50406776 CHEMBL290706 5-hydroxytryptamine receptor 1D Sus scrofa 3.2 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406776&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10251827 163355800 CHEMBL290706 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991578 CN(C)CCc1c[nH]c2ccc(CCc3nc(Cc4ccccc4)no3)cc12 InChI=1S/C23H26N4O/c1-27(2)13-12-19-16-24-21-10-8-18(14-20(19)21)9-11-23-25-22(26-28-23)15-17-6-4-3-5-7-17/h3-8,10,14,16,24H,9,11-13,15H2,1-2H3 KYUWHJMADOFUBT-UHFFFAOYSA-N 50406777 CHEMBL440848 5-hydroxytryptamine receptor 1D Sus scrofa 13 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406777&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10452058 163355801 CHEMBL440848 ZINC00599299 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991579 CC(=O)Nc1ccc(Cc2noc(Cc3ccc4[nH]cc(CCN)c4c3)n2)cc1 InChI=1S/C22H23N5O2/c1-14(28)25-18-5-2-15(3-6-18)11-21-26-22(29-27-21)12-16-4-7-20-19(10-16)17(8-9-23)13-24-20/h2-7,10,13,24H,8-9,11-12,23H2,1H3,(H,25,28) OOLWBBTZIFDOEN-UHFFFAOYSA-N 50406778 CHEMBL39158 5-hydroxytryptamine receptor 1D Sus scrofa 2.5 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406778&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10068921 163355802 CHEMBL39158 ZINC13827473 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991580 CNC(=O)c1ccc(cc1)-c1noc(Cc2ccc3[nH]cc(CCN(C)C)c3c2)n1 InChI=1S/C23H25N5O2/c1-24-23(29)17-7-5-16(6-8-17)22-26-21(30-27-22)13-15-4-9-20-19(12-15)18(14-25-20)10-11-28(2)3/h4-9,12,14,25H,10-11,13H2,1-3H3,(H,24,29) PRTCSIDNPRTJHA-UHFFFAOYSA-N 50406779 CHEMBL38104 5-hydroxytryptamine receptor 1D Sus scrofa 2 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406779&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10431279 163355803 CHEMBL38104 ZINC13827483 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991581 CN(C)CCc1c[nH]c2ccc(CCc3nc(N)no3)cc12 InChI=1S/C16H21N5O/c1-21(2)8-7-12-10-18-14-5-3-11(9-13(12)14)4-6-15-19-16(17)20-22-15/h3,5,9-10,18H,4,6-8H2,1-2H3,(H2,17,20) CVSXIEGQYNXATH-UHFFFAOYSA-N 50406773 CHEMBL290587 5-hydroxytryptamine receptor 1D Sus scrofa 13 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406773&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10380005 163355797 CHEMBL290587 ZINC13827489 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991583 Cc1noc(CCCc2ccc3[nH]cc(CCN)c3c2)n1 InChI=1S/C16H20N4O/c1-11-19-16(21-20-11)4-2-3-12-5-6-15-14(9-12)13(7-8-17)10-18-15/h5-6,9-10,18H,2-4,7-8,17H2,1H3 FZVHHUSZLLUIQC-UHFFFAOYSA-N 50406780 CHEMBL288961 5-hydroxytryptamine receptor 1D Sus scrofa 5 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406780&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10107953 163355804 CHEMBL288961 ZINC00014699 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991584 NCCc1c[nH]c2ccc(cc12)-c1nc(no1)-c1ccccc1 InChI=1S/C18H16N4O/c19-9-8-14-11-20-16-7-6-13(10-15(14)16)18-21-17(22-23-18)12-4-2-1-3-5-12/h1-7,10-11,20H,8-9,19H2 FDPKHZFSVDEEFR-UHFFFAOYSA-N 50406781 CHEMBL434974 5-hydroxytryptamine receptor 1D Sus scrofa 79 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406781&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10425140 163355805 CHEMBL434974 ZINC13827457 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991585 NCCc1c[nH]c2ccc(cc12)-c1nc(N)no1 InChI=1S/C12H13N5O/c13-4-3-8-6-15-10-2-1-7(5-9(8)10)11-16-12(14)17-18-11/h1-2,5-6,15H,3-4,13H2,(H2,14,17) AZPGZTOVCHWLMC-UHFFFAOYSA-N 50406782 CHEMBL289501 5-hydroxytryptamine receptor 1D Sus scrofa 50 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406782&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10377118 163355806 CHEMBL289501 ZINC13827455 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991586 NCCc1c[nH]c2ccc(cc12)C(N)=O InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) WKZLNEWVIAGNAW-UHFFFAOYSA-N 21392 3-(2-aminoethyl)-1H-indole-5-carboxamide::5-CT::5-CT,DP::5-carboxamidotryptamine::CHEMBL1256863::CHEMBL18840::[3H]-5-CT::[3H]-5-Carboxamide tryptamine::[3H]-5-Carboxyamidotryptamine::[3H]-5-carboxamidotryptamine 5-hydroxytryptamine receptor 1D Sus scrofa 4 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21392&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 8K3 1809 49689464 48292 CHEMBL1256863CHEMBL18840 4 ZINC02539813 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991589 NCCc1c[nH]c2ccc(CCc3nc(Cc4ccccc4)no3)cc12 InChI=1S/C21H22N4O/c22-11-10-17-14-23-19-8-6-16(12-18(17)19)7-9-21-24-20(25-26-21)13-15-4-2-1-3-5-15/h1-6,8,12,14,23H,7,9-11,13,22H2 SCFZGOGBRPRNPV-UHFFFAOYSA-N 50406764 CHEMBL39636 5-hydroxytryptamine receptor 1D Sus scrofa 5 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406764&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11725183 163355788 CHEMBL39636 ZINC00014698 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991590 CS(=O)(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3 HKXMQLISPYELRD-UHFFFAOYSA-N 50406771 L-694247 5-hydroxytryptamine receptor 1D Sus scrofa 0.316228 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406771&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 132059 163355795 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991591 CN(C)CCc1c[nH]c2ccc(Cc3nc(C)no3)cc12 InChI=1S/C16H20N4O/c1-11-18-16(21-19-11)9-12-4-5-15-14(8-12)13(10-17-15)6-7-20(2)3/h4-5,8,10,17H,6-7,9H2,1-3H3 PBIQSWDDDJWZKX-UHFFFAOYSA-N 50406769 CHEMBL39296 5-hydroxytryptamine receptor 1D Sus scrofa 50 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406769&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10401626 163355793 CHEMBL39296 ZINC13827481 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991593 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 1D Sus scrofa 10 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search SRO 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991594 CC(=O)NCc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 InChI=1S/C15H17N5O2/c1-9(21)17-8-14-19-15(22-20-14)10-2-3-13-12(6-10)11(4-5-16)7-18-13/h2-3,6-7,18H,4-5,8,16H2,1H3,(H,17,21) IOLHLQDKROZOOC-UHFFFAOYSA-N 50406783 CHEMBL37123 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406783&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10063319 163355807 CHEMBL37123 ZINC13827459 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991595 CCc1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 InChI=1S/C14H16N4O/c1-2-13-17-14(19-18-13)9-3-4-12-11(7-9)10(5-6-15)8-16-12/h3-4,7-8,16H,2,5-6,15H2,1H3 RGZGVSMFNKBYQY-UHFFFAOYSA-N 50406784 CHEMBL289354 5-hydroxytryptamine receptor 1D Sus scrofa 13 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406784&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10332637 163355808 CHEMBL289354 ZINC13827451 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991596 CNS(=O)(=O)c1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 InChI=1S/C20H21N5O3S/c1-22-29(26,27)16-5-2-13(3-6-16)10-19-24-20(28-25-19)14-4-7-18-17(11-14)15(8-9-21)12-23-18/h2-7,11-12,22-23H,8-10,21H2,1H3 RYTUHJYSYWUTTQ-UHFFFAOYSA-N 50406785 CHEMBL39435 5-hydroxytryptamine receptor 1D Sus scrofa 0.251189 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406785&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11742355 163355809 CHEMBL39435 ZINC00599303 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991598 COc1cccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)c1 InChI=1S/C20H20N4O2/c1-25-16-4-2-3-13(9-16)10-19-23-20(26-24-19)14-5-6-18-17(11-14)15(7-8-21)12-22-18/h2-6,9,11-12,22H,7-8,10,21H2,1H3 XYSVDZDGDYOEQP-UHFFFAOYSA-N 50406786 CHEMBL40126 5-hydroxytryptamine receptor 1D Sus scrofa 1.3 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406786&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10247152 163355810 CHEMBL40126 ZINC13827465 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991599 NCCc1c[nH]c2ccc(Cc3nc(Cc4ccccc4)no3)cc12 InChI=1S/C20H20N4O/c21-9-8-16-13-22-18-7-6-15(10-17(16)18)12-20-23-19(24-25-20)11-14-4-2-1-3-5-14/h1-7,10,13,22H,8-9,11-12,21H2 NHIRYTRRCNWYFT-UHFFFAOYSA-N 50406787 CHEMBL289936 5-hydroxytryptamine receptor 1D Sus scrofa 32 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406787&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11724329 163355811 CHEMBL289936 ZINC00014695 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991600 CN(C)CCc1c[nH]c2ccc(cc12)-c1nc(N)no1 InChI=1S/C14H17N5O/c1-19(2)6-5-10-8-16-12-4-3-9(7-11(10)12)13-17-14(15)18-20-13/h3-4,7-8,16H,5-6H2,1-2H3,(H2,15,18) UEGSNYPIMRRODQ-UHFFFAOYSA-N 50406788 CHEMBL35875 5-hydroxytryptamine receptor 1D Sus scrofa 79 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406788&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10265207 163355812 CHEMBL35875 ZINC13827477 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50991605 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00063a003 10.7270/Q22V2HB9 8496922 Street, LJ; Baker, R; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Reeve, AJ; Beer, MS; Middlemiss, DN Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994858 COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21 InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3 ACSDLURGGYXLSE-UHFFFAOYSA-N 50408152 CHEMBL53662 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408152&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10452995 163357176 CHEMBL53662 ZINC52968692 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994861 Fc1ccc(CN2CCN(CC2)c2nc3ccccc3n3cccc23)cc1 InChI=1S/C22H21FN4/c23-18-9-7-17(8-10-18)16-25-12-14-26(15-13-25)22-21-6-3-11-27(21)20-5-2-1-4-19(20)24-22/h1-11H,12-16H2 AASFRXJJHSMTFI-UHFFFAOYSA-N 50408155 CHEMBL54125 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408155&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10546440 163357179 CHEMBL54125 ZINC13762482 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994866 COc1ccc2nc(N3CCN(Cc4ccc(F)cc4)CC3)c3cccn3c2n1 InChI=1S/C22H22FN5O/c1-29-20-9-8-18-21(25-20)28-10-2-3-19(28)22(24-18)27-13-11-26(12-14-27)15-16-4-6-17(23)7-5-16/h2-10H,11-15H2,1H3 ARCIIEQRTPPAQU-UHFFFAOYSA-N 50408156 CHEMBL52800 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408156&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10715484 163357180 CHEMBL52800 ZINC13762468 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994868 C(Oc1ccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2n1)c1ccccc1 InChI=1S/C28H27N5O/c1-3-8-22(9-4-1)20-31-16-18-32(19-17-31)28-25-12-7-15-33(25)27-24(29-28)13-14-26(30-27)34-21-23-10-5-2-6-11-23/h1-15H,16-21H2 TWVWKVHMRMXBRT-UHFFFAOYSA-N 50408153 CHEMBL51675 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408153&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11797762 163357177 CHEMBL51675 ZINC13762460 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994869 Fc1ccc(CN2CCN(CC2)c2nc3sccc3n3cccc23)cc1 InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 YTWMOTHGBHTPOA-UHFFFAOYSA-N 50407789 CHEMBL52772 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407789&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10808909 163356813 CHEMBL52772 ZINC13755965 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994871 C(N1CCN(CC1)c1nc2ccsc2n2cccc12)c1ccccc1 InChI=1S/C20H20N4S/c1-2-5-16(6-3-1)15-22-10-12-23(13-11-22)19-18-7-4-9-24(18)20-17(21-19)8-14-25-20/h1-9,14H,10-13,15H2 QYWDOJXSLBBWLE-UHFFFAOYSA-N 50407786 CHEMBL54720 5-hydroxytryptamine receptor 1D Sus scrofa 14125.38 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407786&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9863146 163356810 CHEMBL54720 ZINC52968850 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994879 Cc1ccnc2c1nc(N1CCN(Cc3ccccc3)CC1)c1cccn21 InChI=1S/C22H23N5/c1-17-9-10-23-22-20(17)24-21(19-8-5-11-27(19)22)26-14-12-25(13-15-26)16-18-6-3-2-4-7-18/h2-11H,12-16H2,1H3 ZHKBEFRQNFTOHD-UHFFFAOYSA-N 50408161 CHEMBL54246 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408161&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10498554 163357185 CHEMBL54246 ZINC13762464 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994883 C(N1CCN(CC1)c1nc2ccc3ncccc3c2n2cccc12)c1ccccc1 InChI=1S/C25H23N5/c1-2-6-19(7-3-1)18-28-14-16-29(17-15-28)25-23-9-5-13-30(23)24-20-8-4-12-26-21(20)10-11-22(24)27-25/h1-13H,14-18H2 VQMVUGKLGFORBP-UHFFFAOYSA-N 50408154 CHEMBL50740 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408154&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10834414 163357178 CHEMBL50740 ZINC13762490 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994892 CN1CCN(CC1)c1nc2cccnc2n2cccc12 InChI=1S/C15H17N5/c1-18-8-10-19(11-9-18)15-13-5-3-7-20(13)14-12(17-15)4-2-6-16-14/h2-7H,8-11H2,1H3 AJVFZHILGGIADJ-UHFFFAOYSA-N 50081975 6-(4-Methyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1,2-a]pyrazine::CHEMBL54914 5-hydroxytryptamine receptor 1D Sus scrofa 954.99 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081975&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 19978038 103981908 CHEMBL54914 ZINC00019265 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994893 Fc1ccc(CN2CCN(CC2)c2nc3cccnc3n3cccc23)cc1 InChI=1S/C21H20FN5/c22-17-7-5-16(6-8-17)15-25-11-13-26(14-12-25)21-19-4-2-10-27(19)20-18(24-21)3-1-9-23-20/h1-10H,11-15H2 HSLUKGWVBNRWNC-UHFFFAOYSA-N 50408164 CHEMBL52625 5-hydroxytryptamine receptor 1D Sus scrofa 83176.38 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408164&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10666301 163357188 CHEMBL52625 ZINC13762466 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994907 C1CN(CCN1)c1nc2ccsc2n2cccc12 InChI=1S/C13H14N4S/c1-2-11-12(16-7-4-14-5-8-16)15-10-3-9-18-13(10)17(11)6-1/h1-3,6,9,14H,4-5,7-8H2 XYOILXJZQNPSEP-UHFFFAOYSA-N 50407769 CHEMBL301765 5-hydroxytryptamine receptor 1D Sus scrofa 602.56 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407769&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 15226949 163356793 CHEMBL301765 ZINC00017124 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994908 C1CN(CCN1)c1ccc2ccccc2n1 InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2 XRXDAJYKGWNHTQ-UHFFFAOYSA-N 50014407 2-(piperazin-1-yl)quinoline::2-Piperazin-1-yl-quinoline::2-Piperazin-1-yl-quinoline (Quipazine)::2-Piperazin-1-yl-quinoline(Quipazine)::CHEMBL18772::QUIPAZINE 5-hydroxytryptamine receptor 1D Sus scrofa 3715.35 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014407&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5011 103926392 CHEMBL18772 173 ZINC19376338 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994913 C1CN(CCN1)c1nc2cccnc2n2cccc12 InChI=1S/C14H15N5/c1-3-11-13(16-5-1)19-8-2-4-12(19)14(17-11)18-9-6-15-7-10-18/h1-5,8,15H,6-7,9-10H2 BBZRRZHQHYRCIA-UHFFFAOYSA-N 50408171 CHEMBL53490 5-hydroxytryptamine receptor 1D Sus scrofa 1698.24 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408171&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10753377 163357195 CHEMBL53490 ZINC00019264 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994914 C1CN(CCN1c1ccccc1)c1nc2cccnc2n2cccc12 InChI=1S/C20H19N5/c1-2-6-16(7-3-1)23-12-14-24(15-13-23)20-18-9-5-11-25(18)19-17(22-20)8-4-10-21-19/h1-11H,12-15H2 OYGFMRULGQRDBW-UHFFFAOYSA-N 50408172 CHEMBL51225 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408172&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10853821 163357196 CHEMBL51225 ZINC13762474 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994915 Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2 PSGBSWDRJJWEDY-UHFFFAOYSA-N 50408151 CHEMBL299524 5-hydroxytryptamine receptor 1D Sus scrofa 85113.8 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408151&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10714457 163357175 CHEMBL299524 ZINC29480316 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994917 C(N1CCN(CC1)c1ncccc1-n1cccc1)c1ccccc1 InChI=1S/C20H22N4/c1-2-7-18(8-3-1)17-22-13-15-24(16-14-22)20-19(9-6-10-21-20)23-11-4-5-12-23/h1-12H,13-17H2 FMWXWOAWFBYPCO-UHFFFAOYSA-N 50408173 CHEMBL52612 5-hydroxytryptamine receptor 1D Sus scrofa 10964.78 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408173&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10519608 163357197 CHEMBL52612 ZINC13762478 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994923 C(N1CCN(CC1)c1nc2cccnc2n2cccc12)c1ccc2OCOc2c1 InChI=1S/C22H21N5O2/c1-3-17-21(23-7-1)27-8-2-4-18(27)22(24-17)26-11-9-25(10-12-26)14-16-5-6-19-20(13-16)29-15-28-19/h1-8,13H,9-12,14-15H2 AZJGEHAZLNOBGW-UHFFFAOYSA-N 50408168 CHEMBL49932 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408168&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10548259 163357192 CHEMBL49932 ZINC01540240 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994927 COc1ccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2n1 InChI=1S/C22H23N5O/c1-28-20-10-9-18-21(24-20)27-11-5-8-19(27)22(23-18)26-14-12-25(13-15-26)16-17-6-3-2-4-7-17/h2-11H,12-16H2,1H3 SXXANLLRNHHDSR-UHFFFAOYSA-N 50408174 CHEMBL300725 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408174&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10667071 163357198 CHEMBL300725 ZINC13762458 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994935 Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1 InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2 BUOWEEIISDGZDM-UHFFFAOYSA-N 50408175 CHEMBL410531 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408175&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10620679 163357199 CHEMBL410531 ZINC13762484 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994940 CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3 LXFHSCDLMBZYKY-UHFFFAOYSA-N 81497 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline::CAS_109028-10-6::CGS 12066B::CHEMBL27403::NSC_123945 5-hydroxytryptamine receptor 1D Sus scrofa 123.03 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81497&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 2689 131342071 CHEMBL27403 ZINC02516018 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994948 C(N1CCN(CC1)c1ccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2n1)c1ccccc1 InChI=1S/C32H35N7/c1-3-8-26(9-4-1)24-35-16-20-37(21-17-35)30-14-13-28-31(34-30)39-15-7-12-29(39)32(33-28)38-22-18-36(19-23-38)25-27-10-5-2-6-11-27/h1-15H,16-25H2 DEMZYMHKNNMIGU-UHFFFAOYSA-N 50408169 CHEMBL53195 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408169&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10553922 163357193 CHEMBL53195 ZINC13762462 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994949 Clc1ccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2c1 InChI=1S/C22H21ClN4/c23-18-8-9-19-21(15-18)27-10-4-7-20(27)22(24-19)26-13-11-25(12-14-26)16-17-5-2-1-3-6-17/h1-10,15H,11-14,16H2 YMQVTFAERCACRG-UHFFFAOYSA-N 50408157 CHEMBL432897 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408157&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10619583 163357181 CHEMBL432897 ZINC13762480 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994952 C(N1CCN(CC1)c1nc2ccc3ncccc3c2n2cccc12)c1ccc2OCOc2c1 InChI=1S/C26H23N5O2/c1-3-19-20(27-9-1)6-7-21-25(19)31-10-2-4-22(31)26(28-21)30-13-11-29(12-14-30)16-18-5-8-23-24(15-18)33-17-32-23/h1-10,15H,11-14,16-17H2 YVTHPCKJOKJJHA-UHFFFAOYSA-N 50408163 CHEMBL52867 5-hydroxytryptamine receptor 1D Sus scrofa 39810.72 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408163&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11797241 163357187 CHEMBL52867 ZINC13762492 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994954 Cc1ccnc2c1nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21 InChI=1S/C22H22FN5/c1-16-8-9-24-22-20(16)25-21(19-3-2-10-28(19)22)27-13-11-26(12-14-27)15-17-4-6-18(23)7-5-17/h2-10H,11-15H2,1H3 AOIREBHOLIZUIV-UHFFFAOYSA-N 50408176 CHEMBL298649 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408176&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10714509 163357200 CHEMBL298649 ZINC13762470 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994971 Clc1ccc2c(c1)nc(N1CCN(Cc3ccccc3)CC1)c1cccn21 InChI=1S/C22H21ClN4/c23-18-8-9-20-19(15-18)24-22(21-7-4-10-27(20)21)26-13-11-25(12-14-26)16-17-5-2-1-3-6-17/h1-10,15H,11-14,16H2 SEYPHWUAVBLMMR-UHFFFAOYSA-N 50408162 CHEMBL299634 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408162&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10738329 163357186 CHEMBL299634 ZINC53113467 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994974 C=CCN1CCN(CC1)c1nc2cccnc2n2cccc12 InChI=1S/C17H19N5/c1-2-8-20-10-12-21(13-11-20)17-15-6-4-9-22(15)16-14(19-17)5-3-7-18-16/h2-7,9H,1,8,10-13H2 WJOCTGQTKHSAJN-UHFFFAOYSA-N 50408165 CHEMBL299231 5-hydroxytryptamine receptor 1D Sus scrofa 954.99 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408165&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10637485 163357189 CHEMBL299231 ZINC13762456 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994979 C(N1CCN(CC1)c1nc2cccnc2n2cccc12)c1ccccc1 InChI=1S/C21H21N5/c1-2-6-17(7-3-1)16-24-12-14-25(15-13-24)21-19-9-5-11-26(19)20-18(23-21)8-4-10-22-20/h1-11H,12-16H2 QMPYBDXJTRQRLN-UHFFFAOYSA-N 50058283 6-(4-Benzyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1,2-a]pyrazine::CHEMBL53573 5-hydroxytryptamine receptor 1D Sus scrofa 29512.09 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058283&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9841032 103954259 CHEMBL53573 ZINC53294322 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994983 Cc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn21 InChI=1S/C23H23FN4/c1-17-4-9-21-20(15-17)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-18-5-7-19(24)8-6-18/h2-10,15H,11-14,16H2,1H3 JUSBDZIBILCYFG-UHFFFAOYSA-N 50408159 CHEMBL300692 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408159&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10571450 163357183 CHEMBL300692 ZINC13762486 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994991 C=CCN1CCN(CC1)c1nc2sccc2n2cccc12 InChI=1S/C16H18N4S/c1-2-6-18-8-10-19(11-9-18)15-13-4-3-7-20(13)14-5-12-21-16(14)17-15/h2-5,7,12H,1,6,8-11H2 RCXDTIWYBMIRHQ-UHFFFAOYSA-N 50407784 CHEMBL51118 5-hydroxytryptamine receptor 1D Sus scrofa 467.74 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407784&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10756517 163356808 CHEMBL51118 ZINC13755960 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994992 Clc1ccc2c(c1)nc(N1CCN(Cc3ccc4OCOc4c3)CC1)c1cccn21 InChI=1S/C23H21ClN4O2/c24-17-4-5-19-18(13-17)25-23(20-2-1-7-28(19)20)27-10-8-26(9-11-27)14-16-3-6-21-22(12-16)30-15-29-21/h1-7,12-13H,8-11,14-15H2 KDCOAGQKBBVYDB-UHFFFAOYSA-N 50408166 CHEMBL416662 5-hydroxytryptamine receptor 1D Sus scrofa 46773.51 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408166&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 19978059 163357190 CHEMBL416662 ZINC01540239 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994993 C=CCN1CCN(CC1)c1nc2ccc3ncccc3c2n2cccc12 InChI=1S/C21H21N5/c1-2-10-24-12-14-25(15-13-24)21-19-6-4-11-26(19)20-16-5-3-9-22-17(16)7-8-18(20)23-21/h2-9,11H,1,10,12-15H2 ILDJOTZORZWBSP-UHFFFAOYSA-N 50408170 CHEMBL299097 5-hydroxytryptamine receptor 1D Sus scrofa 5754.4 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408170&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10569395 163357194 CHEMBL299097 ZINC13762494 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994997 C(N1CCN(CC1)c1nc2ccccc2n2cccc12)c1ccccc1 InChI=1S/C22H22N4/c1-2-7-18(8-3-1)17-24-13-15-25(16-14-24)22-21-11-6-12-26(21)20-10-5-4-9-19(20)23-22/h1-12H,13-17H2 PADMFNVKWGURLR-UHFFFAOYSA-N 50408167 CHEMBL53416 5-hydroxytryptamine receptor 1D Sus scrofa 23988.33 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408167&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10617292 163357191 CHEMBL53416 ZINC53294342 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50995009 CCOC(=O)N1CCN(CC1)c1nc2cccnc2n2cccc12 InChI=1S/C17H19N5O2/c1-2-24-17(23)21-11-9-20(10-12-21)16-14-6-4-8-22(14)15-13(19-16)5-3-7-18-15/h3-8H,2,9-12H2,1H3 URLYEVZCOFLWKV-UHFFFAOYSA-N 50408160 CHEMBL52007 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408160&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10663820 163357184 CHEMBL52007 ZINC13762476 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50995013 Clc1ccc(CN2CCN(CC2)c2nc3cccnc3n3cccc23)c(Cl)c1 InChI=1S/C21H19Cl2N5/c22-16-6-5-15(17(23)13-16)14-26-9-11-27(12-10-26)21-19-4-2-8-28(19)20-18(25-21)3-1-7-24-20/h1-8,13H,9-12,14H2 CKJCINZQXPNLOV-UHFFFAOYSA-N 50408158 CHEMBL50456 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408158&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10645335 163357182 CHEMBL50456 ZINC13762472 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50995019 COc1ccc2c(c1)nc(N1CCN(CCCCn3cccn3)CC1)c1cccn21 InChI=1S/C23H28N6O/c1-30-19-7-8-21-20(18-19)25-23(22-6-4-13-29(21)22)27-16-14-26(15-17-27)10-2-3-11-28-12-5-9-24-28/h4-9,12-13,18H,2-3,10-11,14-17H2,1H3 NOIZELMBLJHYSX-UHFFFAOYSA-N 50408150 CHEMBL415933 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm960501o 10.7270/Q20R9QMC 9191957 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408150&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 44296810 163357174 CHEMBL415933 ZINC13762488 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993795 C(\C=C\c1ccccc1)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C22H22N4S/c1-2-6-18(7-3-1)8-4-11-24-13-15-25(16-14-24)21-20-9-5-12-26(20)22-19(23-21)10-17-27-22/h1-10,12,17H,11,13-16H2/b8-4+ DXTRNUSQQPMWSC-XBXARRHUSA-N 50407750 CHEMBL261977 5-hydroxytryptamine receptor 1D Sus scrofa 104712.85 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407750&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10833258 163356774 CHEMBL261977 ZINC13755944 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993805 FC(F)(F)c1cccc(c1)N1CCN(CC1)c1nc2scc(-c3ccccc3)c2n2cccc12 InChI=1S/C26H21F3N4S/c27-26(28,29)19-8-4-9-20(16-19)31-12-14-32(15-13-31)24-22-10-5-11-33(22)23-21(17-34-25(23)30-24)18-6-2-1-3-7-18/h1-11,16-17H,12-15H2 HEUZTEKWBIBQQP-UHFFFAOYSA-N 50407758 CHEMBL62902 5-hydroxytryptamine receptor 1D Sus scrofa 35481.34 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407758&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10576618 163356782 CHEMBL62902 ZINC13755983 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993808 FC(F)(F)c1cccc(c1)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C20H17F3N4S/c21-20(22,23)14-3-1-4-15(13-14)25-8-10-26(11-9-25)18-17-5-2-7-27(17)19-16(24-18)6-12-28-19/h1-7,12-13H,8-11H2 UOPMUBWAOQBXJF-UHFFFAOYSA-N 50407760 CHEMBL68390 5-hydroxytryptamine receptor 1D Sus scrofa 1258.93 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407760&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10621131 163356784 CHEMBL68390 ZINC13755928 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993809 CCOC(=O)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C16H18N4O2S/c1-2-22-16(21)19-9-7-18(8-10-19)14-13-4-3-6-20(13)15-12(17-14)5-11-23-15/h3-6,11H,2,7-10H2,1H3 DLRDSROWZPGGDS-UHFFFAOYSA-N 50407761 CHEMBL63289 5-hydroxytryptamine receptor 1D Sus scrofa 512861.38 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407761&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10687868 163356785 CHEMBL63289 ZINC13755950 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993814 C1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C14H15N3S/c1-2-7-16(8-3-1)13-12-5-4-9-17(12)14-11(15-13)6-10-18-14/h4-6,9-10H,1-3,7-8H2 AKSHVAMBSAMQEI-UHFFFAOYSA-N 50407759 CHEMBL63114 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407759&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10539093 163356783 CHEMBL63114 ZINC13755930 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993816 CCOC(=O)CN1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C17H20N4O2S/c1-2-23-15(22)12-19-7-9-20(10-8-19)16-14-4-3-6-21(14)17-13(18-16)5-11-24-17/h3-6,11H,2,7-10,12H2,1H3 PQWUNHKJEXFYJI-UHFFFAOYSA-N 50407766 CHEMBL293879 5-hydroxytryptamine receptor 1D Sus scrofa 100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407766&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10569470 163356790 CHEMBL293879 ZINC13755952 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993817 CN1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C14H16N4S/c1-16-6-8-17(9-7-16)13-12-3-2-5-18(12)14-11(15-13)4-10-19-14/h2-5,10H,6-9H2,1H3 OYQJNUJWLVFCPE-UHFFFAOYSA-N 50407767 CHEMBL65974 5-hydroxytryptamine receptor 1D Sus scrofa 398.11 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407767&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10516340 163356791 CHEMBL65974 ZINC00017125 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993818 FC(F)(F)c1cccc(c1)N1CCN(CC1)c1nc2sccc2n2cccc12 InChI=1S/C20H17F3N4S/c21-20(22,23)14-3-1-4-15(13-14)25-8-10-26(11-9-25)18-16-5-2-7-27(16)17-6-12-28-19(17)24-18/h1-7,12-13H,8-11H2 HGYNWZFKHCMJGM-UHFFFAOYSA-N 50407768 CHEMBL63845 5-hydroxytryptamine receptor 1D Sus scrofa 57543.99 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407768&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10573164 163356792 CHEMBL63845 ZINC13755962 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993827 C1CN(CCN1)c1ccc2ccccc2n1 InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2 XRXDAJYKGWNHTQ-UHFFFAOYSA-N 50014407 2-(piperazin-1-yl)quinoline::2-Piperazin-1-yl-quinoline::2-Piperazin-1-yl-quinoline (Quipazine)::2-Piperazin-1-yl-quinoline(Quipazine)::CHEMBL18772::QUIPAZINE 5-hydroxytryptamine receptor 1D Sus scrofa 3715.35 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014407&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5011 103926392 CHEMBL18772 173 ZINC19376338 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993832 Clc1ccc(cc1)C(N1CCN(CC1)c1nc2ccsc2n2cccc12)c1ccccc1 InChI=1S/C26H23ClN4S/c27-21-10-8-20(9-11-21)24(19-5-2-1-3-6-19)29-14-16-30(17-15-29)25-23-7-4-13-31(23)26-22(28-25)12-18-32-26/h1-13,18,24H,14-17H2 DFXLNCRNORESIF-UHFFFAOYSA-N 50407776 CHEMBL66307 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407776&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10718731 163356800 CHEMBL66307 ZINC13755940 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993836 C(N1CCN(CC1)c1nc2sc(cc2n2cccc12)-c1ccccc1)c1ccccc1 InChI=1S/C26H24N4S/c1-3-8-20(9-4-1)19-28-14-16-29(17-15-28)25-22-12-7-13-30(22)23-18-24(31-26(23)27-25)21-10-5-2-6-11-21/h1-13,18H,14-17,19H2 UJCWXFPFFHIOCY-UHFFFAOYSA-N 50407779 CHEMBL66408 5-hydroxytryptamine receptor 1D Sus scrofa 537031.8 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407779&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10526362 163356803 CHEMBL66408 ZINC13755985 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993840 C(N1CCN(CC1)c1nc2sccc2n2cccc12)c1ccc2OCOc2c1 InChI=1S/C21H20N4O2S/c1-2-16-20(22-21-17(5-11-28-21)25(16)6-1)24-9-7-23(8-10-24)13-15-3-4-18-19(12-15)27-14-26-18/h1-6,11-12H,7-10,13-14H2 OUZIPSMKVVNNRW-UHFFFAOYSA-N 50407762 CHEMBL292725 5-hydroxytryptamine receptor 1D Sus scrofa 19952.62 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407762&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10739272 163356786 CHEMBL292725 ZINC13755970 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993841 CN1CCN(CC1)c1nc2sccc2n2cccc12 InChI=1S/C14H16N4S/c1-16-6-8-17(9-7-16)13-11-3-2-5-18(11)12-4-10-19-14(12)15-13/h2-5,10H,6-9H2,1H3 CMBPNOCCPKFOHS-UHFFFAOYSA-N 50407774 CHEMBL302225 5-hydroxytryptamine receptor 1D Sus scrofa 912 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407774&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10826076 163356798 CHEMBL302225 ZINC13755958 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993848 C(C1CC1)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C17H20N4S/c1-2-15-16(18-14-5-11-22-17(14)21(15)6-1)20-9-7-19(8-10-20)12-13-3-4-13/h1-2,5-6,11,13H,3-4,7-10,12H2 CYUNIDFFVZCUDT-UHFFFAOYSA-N 50407773 CHEMBL65736 5-hydroxytryptamine receptor 1D Sus scrofa 2570.4 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407773&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10852612 163356797 CHEMBL65736 ZINC13755946 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993849 FC(F)(F)c1cccc(c1)N1CCN(CC1)c1nc2cc(sc2n2cccc12)-c1ccccc1 InChI=1S/C26H21F3N4S/c27-26(28,29)19-8-4-9-20(16-19)31-12-14-32(15-13-31)24-22-10-5-11-33(22)25-21(30-24)17-23(34-25)18-6-2-1-3-7-18/h1-11,16-17H,12-15H2 LBCCJNLNXBZJDX-UHFFFAOYSA-N 50407775 CHEMBL293219 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407775&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10790813 163356799 CHEMBL293219 ZINC13755975 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993855 C=CCN1CCN(CC1)c1nc2sccc2n2cccc12 InChI=1S/C16H18N4S/c1-2-6-18-8-10-19(11-9-18)15-13-4-3-7-20(13)14-5-12-21-16(14)17-15/h2-5,7,12H,1,6,8-11H2 RCXDTIWYBMIRHQ-UHFFFAOYSA-N 50407784 CHEMBL51118 5-hydroxytryptamine receptor 1D Sus scrofa 467.74 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407784&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10756517 163356808 CHEMBL51118 ZINC13755960 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993856 C=CCN1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C16H18N4S/c1-2-6-18-8-10-19(11-9-18)15-14-4-3-7-20(14)16-13(17-15)5-12-21-16/h2-5,7,12H,1,6,8-11H2 MSVKSHZVXNPCBB-UHFFFAOYSA-N 50407785 CHEMBL62274 5-hydroxytryptamine receptor 1D Sus scrofa 380.19 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407785&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10590206 163356809 CHEMBL62274 ZINC13755925 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993857 C(N1CCN(CC1)c1nc2scc(-c3ccccc3)c2n2cccc12)c1ccccc1 InChI=1S/C26H24N4S/c1-3-8-20(9-4-1)18-28-14-16-29(17-15-28)25-23-12-7-13-30(23)24-22(19-31-26(24)27-25)21-10-5-2-6-11-21/h1-13,19H,14-18H2 RQPNBYPBNQHGRL-UHFFFAOYSA-N 50407780 CHEMBL302447 5-hydroxytryptamine receptor 1D Sus scrofa 30902.95 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407780&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10622257 163356804 CHEMBL302447 ZINC13755987 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993858 C(N1CCN(CC1)c1nc2ccsc2n2cccc12)c1ccccc1 InChI=1S/C20H20N4S/c1-2-5-16(6-3-1)15-22-10-12-23(13-11-22)19-18-7-4-9-24(18)20-17(21-19)8-14-25-20/h1-9,14H,10-13,15H2 QYWDOJXSLBBWLE-UHFFFAOYSA-N 50407786 CHEMBL54720 5-hydroxytryptamine receptor 1D Sus scrofa 14125.38 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407786&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9863146 163356810 CHEMBL54720 ZINC52968850 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993869 C(N1CCN(CC1)c1nc2sccc2n2cccc12)c1ccccc1 InChI=1S/C20H20N4S/c1-2-5-16(6-3-1)15-22-10-12-23(13-11-22)19-17-7-4-9-24(17)18-8-14-25-20(18)21-19/h1-9,14H,10-13,15H2 OYASVWZGKNBLSA-UHFFFAOYSA-N 50407777 CHEMBL65710 5-hydroxytryptamine receptor 1D Sus scrofa 93325.43 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407777&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10247171 163356801 CHEMBL65710 ZINC13755964 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993870 Fc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C20H17FN4OS/c21-15-5-3-14(4-6-15)19(26)24-11-9-23(10-12-24)18-17-2-1-8-25(17)20-16(22-18)7-13-27-20/h1-8,13H,9-12H2 UJBVSJAOMNPPER-UHFFFAOYSA-N 50407764 CHEMBL417570 5-hydroxytryptamine receptor 1D Sus scrofa 128824.96 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407764&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10547809 163356788 CHEMBL417570 ZINC13755955 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993873 Fc1ccc(CN2CCN(CC2)c2nc3sccc3n3cccc23)cc1 InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 YTWMOTHGBHTPOA-UHFFFAOYSA-N 50407789 CHEMBL52772 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407789&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10808909 163356813 CHEMBL52772 ZINC13755965 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993874 C1CN(CCN1)c1nc2cc(sc2n2cccc12)-c1ccccc1 InChI=1S/C19H18N4S/c1-2-5-14(6-3-1)17-13-15-19(24-17)23-10-4-7-16(23)18(21-15)22-11-8-20-9-12-22/h1-7,10,13,20H,8-9,11-12H2 DYFVORIBDGMRNZ-UHFFFAOYSA-N 50407787 CHEMBL62445 5-hydroxytryptamine receptor 1D Sus scrofa 35481.34 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407787&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10568745 163356811 CHEMBL62445 ZINC13755971 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993889 C1CN(CCN1c1ccccc1)c1nc2ccsc2n2cccc12 InChI=1S/C19H18N4S/c1-2-5-15(6-3-1)21-10-12-22(13-11-21)18-17-7-4-9-23(17)19-16(20-18)8-14-24-19/h1-9,14H,10-13H2 ZJCWWTLTVPRANX-UHFFFAOYSA-N 50407793 CHEMBL302104 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407793&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10496957 163356817 CHEMBL302104 ZINC26181408 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993890 Fc1ccc(CN2CCN(Cc3nc4ccsc4n4cccc34)CC2)cc1 InChI=1S/C21H21FN4S/c22-17-5-3-16(4-6-17)14-24-9-11-25(12-10-24)15-19-20-2-1-8-26(20)21-18(23-19)7-13-27-21/h1-8,13H,9-12,14-15H2 QUJXTOCQGXKMEK-UHFFFAOYSA-N 50407792 CHEMBL64903 5-hydroxytryptamine receptor 1D Sus scrofa 38018.94 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407792&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 44305547 163356816 CHEMBL64903 ZINC22938347 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993904 Clc1ccc(CN2CCN(CC2)c2nc3sccc3n3cccc23)c(Cl)c1 InChI=1S/C20H18Cl2N4S/c21-15-4-3-14(16(22)12-15)13-24-7-9-25(10-8-24)19-17-2-1-6-26(17)18-5-11-27-20(18)23-19/h1-6,11-12H,7-10,13H2 MRVXWRYYLBBDQJ-UHFFFAOYSA-N 50407791 CHEMBL64727 5-hydroxytryptamine receptor 1D Sus scrofa 25118.86 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407791&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10598044 163356815 CHEMBL64727 ZINC13755966 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993914 CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F InChI=1S/C17H17F3N4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16/h2-6,11H,7-10H2,1H3 LXFHSCDLMBZYKY-UHFFFAOYSA-N 81497 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline::CAS_109028-10-6::CGS 12066B::CHEMBL27403::NSC_123945 5-hydroxytryptamine receptor 1D Sus scrofa 123.03 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81497&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 2689 131342071 CHEMBL27403 ZINC02516018 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993917 FC(F)(F)c1cccc(c1)N1CCN(CC1)c1nc2sc(cc2n2cccc12)-c1ccccc1 InChI=1S/C26H21F3N4S/c27-26(28,29)19-8-4-9-20(16-19)31-12-14-32(15-13-31)24-21-10-5-11-33(21)22-17-23(34-25(22)30-24)18-6-2-1-3-7-18/h1-11,16-17H,12-15H2 VFBDQDRLYCWTOU-UHFFFAOYSA-N 50407770 CHEMBL64559 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407770&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10814515 163356794 CHEMBL64559 ZINC13755982 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993922 C(N1CCN(CC1)c1nc2ccsc2n2cccc12)c1ccc2OCOc2c1 InChI=1S/C21H20N4O2S/c1-2-17-20(22-16-5-11-28-21(16)25(17)6-1)24-9-7-23(8-10-24)13-15-3-4-18-19(12-15)27-14-26-18/h1-6,11-12H,7-10,13-14H2 IURWVMMKDXJLTR-UHFFFAOYSA-N 50407790 CHEMBL63790 5-hydroxytryptamine receptor 1D Sus scrofa 36307.81 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407790&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11794853 163356814 CHEMBL63790 ZINC13755936 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993924 Fc1ccc(cc1)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C19H17FN4S/c20-14-3-5-15(6-4-14)22-9-11-23(12-10-22)18-17-2-1-8-24(17)19-16(21-18)7-13-25-19/h1-8,13H,9-12H2 JELVCMOTKGSBCH-UHFFFAOYSA-N 50407771 CHEMBL63905 5-hydroxytryptamine receptor 1D Sus scrofa 275422.87 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407771&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10689339 163356795 CHEMBL63905 ZINC13755927 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993926 C1CN(CC=C1)c1nc2ccsc2n2cccc12 InChI=1S/C14H13N3S/c1-2-7-16(8-3-1)13-12-5-4-9-17(12)14-11(15-13)6-10-18-14/h1-2,4-6,9-10H,3,7-8H2 VZWGNPPCNCQGBZ-UHFFFAOYSA-N 50407757 CHEMBL65212 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407757&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 44306007 163356781 CHEMBL65212 ZINC13755931 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993927 FC(F)(F)c1ccccc1CCN1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C22H21F3N4S/c23-22(24,25)17-5-2-1-4-16(17)7-10-27-11-13-28(14-12-27)20-19-6-3-9-29(19)21-18(26-20)8-15-30-21/h1-6,8-9,15H,7,10-14H2 FQHKGSXYDVSJCE-UHFFFAOYSA-N 50407755 CHEMBL63713 5-hydroxytryptamine receptor 1D Sus scrofa 199526.23 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407755&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10717512 163356779 CHEMBL63713 ZINC13755942 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993928 C[N+]1(Cc2ccccc2)CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C21H23N4S/c1-25(16-17-6-3-2-4-7-17)13-11-23(12-14-25)20-19-8-5-10-24(19)21-18(22-20)9-15-26-21/h2-10,15H,11-14,16H2,1H3/q+1 CHXZPUOMGXBHFG-UHFFFAOYSA-N 50407756 CHEMBL62911 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407756&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10719857 163356780 CHEMBL62911 ZINC13755948 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993930 C1CN(CCO1)c1nc2ccsc2n2cccc12 InChI=1S/C13H13N3OS/c1-2-11-12(15-5-7-17-8-6-15)14-10-3-9-18-13(10)16(11)4-1/h1-4,9H,5-8H2 MQRSAESBFCOHPH-UHFFFAOYSA-N 50407765 CHEMBL292293 5-hydroxytryptamine receptor 1D Sus scrofa 93325.43 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407765&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10777682 163356789 CHEMBL292293 ZINC13755929 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993931 CN1CCN(CC1)c1nc2sc(cc2n2cccc12)-c1ccccc1 InChI=1S/C20H20N4S/c1-22-10-12-23(13-11-22)19-16-8-5-9-24(16)17-14-18(25-20(17)21-19)15-6-3-2-4-7-15/h2-9,14H,10-13H2,1H3 DRJDHULKURBTLQ-UHFFFAOYSA-N 50407788 CHEMBL65669 5-hydroxytryptamine receptor 1D Sus scrofa 60255.96 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407788&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10665419 163356812 CHEMBL65669 ZINC13755980 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993947 Clc1ccc(CN2CCN(CC2)c2nc3ccsc3n3cccc23)c(Cl)c1 InChI=1S/C20H18Cl2N4S/c21-15-4-3-14(16(22)12-15)13-24-7-9-25(10-8-24)19-18-2-1-6-26(18)20-17(23-19)5-11-27-20/h1-6,11-12H,7-10,13H2 ZDPNKNSRWQOPMC-UHFFFAOYSA-N 50407752 CHEMBL294368 5-hydroxytryptamine receptor 1D Sus scrofa 3090.3 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407752&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10645615 163356776 CHEMBL294368 ZINC13755933 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993950 O=C(CN1CCN(CC1)c1nc2ccsc2n2cccc12)N1CCCC1 InChI=1S/C19H23N5OS/c25-17(22-6-1-2-7-22)14-21-9-11-23(12-10-21)18-16-4-3-8-24(16)19-15(20-18)5-13-26-19/h3-5,8,13H,1-2,6-7,9-12,14H2 BGPSOKRQZWMDEI-UHFFFAOYSA-N 50407763 CHEMBL303986 5-hydroxytryptamine receptor 1D Sus scrofa 251188.64 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407763&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10737848 163356787 CHEMBL303986 ZINC13755954 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993954 Clc1ccc(CN2CCN(CC2)c2nc3sccc3n3cccc23)cc1Cl InChI=1S/C20H18Cl2N4S/c21-15-4-3-14(12-16(15)22)13-24-7-9-25(10-8-24)19-17-2-1-6-26(17)18-5-11-27-20(18)23-19/h1-6,11-12H,7-10,13H2 WYLPBTJCTUPQGN-UHFFFAOYSA-N 50407794 CHEMBL65413 5-hydroxytryptamine receptor 1D Sus scrofa 257039.58 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407794&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11796209 163356818 CHEMBL65413 ZINC13755968 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993959 Clc1ccc(CN2CCN(CC2)c2nc3ccsc3n3cccc23)cc1Cl InChI=1S/C20H18Cl2N4S/c21-15-4-3-14(12-16(15)22)13-24-7-9-25(10-8-24)19-18-2-1-6-26(18)20-17(23-19)5-11-27-20/h1-6,11-12H,7-10,13H2 GRBRTCUKNIBBOG-UHFFFAOYSA-N 50407753 CHEMBL302431 5-hydroxytryptamine receptor 1D Sus scrofa 44668.36 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407753&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10811876 163356777 CHEMBL302431 ZINC13755934 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993975 Fc1ccc(CN2CCN(CC2)c2nc3ccsc3n3cccc23)cc1 InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-18-2-1-8-25(18)20-17(22-19)7-13-26-20/h1-8,13H,9-12,14H2 ANJGZJUIHVVPCI-UHFFFAOYSA-N 50407772 CHEMBL418678 5-hydroxytryptamine receptor 1D Sus scrofa 138038.43 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407772&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11793287 163356796 CHEMBL418678 ZINC13755932 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993986 Clc1ccc(cc1)N1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C19H17ClN4S/c20-14-3-5-15(6-4-14)22-9-11-23(12-10-22)18-17-2-1-8-24(17)19-16(21-18)7-13-25-19/h1-8,13H,9-12H2 YUTYMOJIEPDZRD-UHFFFAOYSA-N 50407781 CHEMBL66310 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407781&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10523090 163356805 CHEMBL66310 ZINC13755926 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50993992 CN1CCN(CC1)c1nc2cc(sc2n2cccc12)-c1ccccc1 InChI=1S/C20H20N4S/c1-22-10-12-23(13-11-22)19-17-8-5-9-24(17)20-16(21-19)14-18(25-20)15-6-3-2-4-7-15/h2-9,14H,10-13H2,1H3 DGWRAIYRSJRMOF-UHFFFAOYSA-N 50407783 CHEMBL62366 5-hydroxytryptamine receptor 1D Sus scrofa 87096.36 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407783&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11792032 163356807 CHEMBL62366 ZINC13755973 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994004 C1CN(CCC1c1ccccc1)c1nc2ccsc2n2cccc12 InChI=1S/C20H19N3S/c1-2-5-15(6-3-1)16-8-12-22(13-9-16)19-18-7-4-11-23(18)20-17(21-19)10-14-24-20/h1-7,10-11,14,16H,8-9,12-13H2 UIWIIDXHKUCNGB-UHFFFAOYSA-N 50407778 CHEMBL63588 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407778&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10568666 163356802 CHEMBL63588 ZINC26187450 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994008 CCCN1CCN(CC1)c1nc2ccsc2n2cccc12 InChI=1S/C16H20N4S/c1-2-6-18-8-10-19(11-9-18)15-14-4-3-7-20(14)16-13(17-15)5-12-21-16/h3-5,7,12H,2,6,8-11H2,1H3 RGJKRQSHUUKABL-UHFFFAOYSA-N 50407754 CHEMBL64948 5-hydroxytryptamine receptor 1D Sus scrofa 134.9 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407754&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10590360 163356778 CHEMBL64948 ZINC13755924 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994010 C(N1CCN(CC1)c1nc2cc(sc2n2cccc12)-c1ccccc1)c1ccccc1 InChI=1S/C26H24N4S/c1-3-8-20(9-4-1)19-28-14-16-29(17-15-28)25-23-12-7-13-30(23)26-22(27-25)18-24(31-26)21-10-5-2-6-11-21/h1-13,18H,14-17,19H2 XVBNTXFFWWXLMY-UHFFFAOYSA-N 50407782 CHEMBL66540 5-hydroxytryptamine receptor 1D Sus scrofa >100000 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407782&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10502452 163356806 CHEMBL66540 ZINC13755977 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994021 C1CN(CCN1)c1nc2ccsc2n2cccc12 InChI=1S/C13H14N4S/c1-2-11-12(16-7-4-14-5-8-16)15-10-3-9-18-13(10)17(11)6-1/h1-3,6,9,14H,4-5,7-8H2 XYOILXJZQNPSEP-UHFFFAOYSA-N 50407769 CHEMBL301765 5-hydroxytryptamine receptor 1D Sus scrofa 602.56 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407769&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 15226949 163356793 CHEMBL301765 ZINC00017124 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50994023 Cc1sc2c(nc(N3CCN(Cc4ccccc4)CC3)c3cccn23)c1C InChI=1S/C22H24N4S/c1-16-17(2)27-22-20(16)23-21(19-9-6-10-26(19)22)25-13-11-24(12-14-25)15-18-7-4-3-5-8-18/h3-10H,11-15H2,1-2H3 BKNVUCYNQODGLA-UHFFFAOYSA-N 50407751 CHEMBL62612 5-hydroxytryptamine receptor 1D Sus scrofa 524807.46 ChEMBL 10.1021/jm950543x 10.7270/Q2T72JNC 8642566 Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Universit£ de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407751&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10809561 163356775 CHEMBL62612 ZINC13755978 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992930 CN(C)CCc1c[nH]c2ccc(Cc3nnn[nH]3)cc12 InChI=1S/C14H18N6/c1-20(2)6-5-11-9-15-13-4-3-10(7-12(11)13)8-14-16-18-19-17-14/h3-4,7,9,15H,5-6,8H2,1-2H3,(H,16,17,18,19) LMSNSIQAWQSERP-UHFFFAOYSA-N 50407352 CHEMBL300209 5-hydroxytryptamine receptor 1D Sus scrofa 3981.07 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407352&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10061694 163356376 CHEMBL300209 ZINC13741369 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992935 CN(C)CCc1c[nH]c2ccc(cc12)-n1cncn1 InChI=1S/C14H17N5/c1-18(2)6-5-11-8-16-14-4-3-12(7-13(11)14)19-10-15-9-17-19/h3-4,7-10,16H,5-6H2,1-2H3 GKKAQRFMUGUZQS-UHFFFAOYSA-N 50407356 CHEMBL54265 5-hydroxytryptamine receptor 1D Sus scrofa 19.95 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407356&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10106412 163356380 CHEMBL54265 ZINC13741364 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992937 CN(C)CCc1c[nH]c2ccc(Cc3nnnn3C)cc12 InChI=1S/C15H20N6/c1-20(2)7-6-12-10-16-14-5-4-11(8-13(12)14)9-15-17-18-19-21(15)3/h4-5,8,10,16H,6-7,9H2,1-3H3 YOPSWVMUSWBXTO-UHFFFAOYSA-N 50407358 CHEMBL53128 5-hydroxytryptamine receptor 1D Sus scrofa 25.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407358&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10062435 163356382 CHEMBL53128 ZINC13741370 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992945 CN(C)CCc1c[nH]c2ccc(Cn3ccnc3C)cc12 InChI=1S/C17H22N4/c1-13-18-7-9-21(13)12-14-4-5-17-16(10-14)15(11-19-17)6-8-20(2)3/h4-5,7,9-11,19H,6,8,12H2,1-3H3 PQJCUCYJHHAAPI-UHFFFAOYSA-N 50407355 CHEMBL53349 5-hydroxytryptamine receptor 1D Sus scrofa 63.1 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407355&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10379049 163356379 CHEMBL53349 ZINC13741359 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992950 CN(C)CCc1c[nH]c2ccc(Cc3ncn(C)n3)cc12 InChI=1S/C16H21N5/c1-20(2)7-6-13-10-17-15-5-4-12(8-14(13)15)9-16-18-11-21(3)19-16/h4-5,8,10-11,17H,6-7,9H2,1-3H3 VRVUZPDUWIVKCG-UHFFFAOYSA-N 50407363 CHEMBL51108 5-hydroxytryptamine receptor 1D Sus scrofa 200 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407363&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10016692 163356387 CHEMBL51108 ZINC13741366 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992951 CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12 InChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3 ULFRLSNUDGIQQP-UHFFFAOYSA-N 50033437 CHEMBL905::MK 462 free base::N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine::N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine::N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine::RIZATRIPTAN::risatriptan 5-hydroxytryptamine receptor 1D Sus scrofa 50.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033437&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5078 103941727 48273 CHEMBL905 DB00953 51 ZINC00005895 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992954 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 1D Sus scrofa 10 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search SRO 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992961 CN(C)CCc1c[nH]c2ccc(Cn3cnnn3)cc12 InChI=1S/C14H18N6/c1-19(2)6-5-12-8-15-14-4-3-11(7-13(12)14)9-20-10-16-17-18-20/h3-4,7-8,10,15H,5-6,9H2,1-2H3 RKQJZPXMZOPXLB-UHFFFAOYSA-N 50407365 CHEMBL53485 5-hydroxytryptamine receptor 1D Sus scrofa 39.81 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407365&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10445845 163356389 CHEMBL53485 ZINC13741362 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992968 CCn1nnc(Cc2ccc3[nH]cc(CCN(C)C)c3c2)n1 InChI=1S/C16H22N6/c1-4-22-19-16(18-20-22)10-12-5-6-15-14(9-12)13(11-17-15)7-8-21(2)3/h5-6,9,11,17H,4,7-8,10H2,1-3H3 IIYLGSKFTYDEID-UHFFFAOYSA-N 50407354 CHEMBL299213 5-hydroxytryptamine receptor 1D Sus scrofa 125.89 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407354&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10063283 163356378 CHEMBL299213 ZINC13741373 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992969 CS(=O)(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3 HKXMQLISPYELRD-UHFFFAOYSA-N 50406771 L-694247 5-hydroxytryptamine receptor 1D Sus scrofa 0.316 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406771&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 132059 163355795 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50992970 CCn1nnnc1Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C16H22N6/c1-4-22-16(18-19-20-22)10-12-5-6-15-14(9-12)13(11-17-15)7-8-21(2)3/h5-6,9,11,17H,4,7-8,10H2,1-3H3 CJBANWVQVZIEGT-UHFFFAOYSA-N 50407351 CHEMBL50834 5-hydroxytryptamine receptor 1D Sus scrofa 25.12 ChEMBL 10.1021/jm00010a025 10.7270/Q20V8DZS 7752204 Street, LJ; Baker, R; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Watt, AP; Beer, MS Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407351&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10108730 163356375 CHEMBL50834 ZINC13741371 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51029610 CN(C)CCc1c[nH]c2ccc(Cc3nc(N)no3)cc12 InChI=1S/C15H19N5O/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19) GJLPUJJLZFRDTA-UHFFFAOYSA-N 50406758 CHEMBL39243 5-hydroxytryptamine receptor 1D Sus scrofa 25 ChEMBL 10.1016/S0960-894X(00)80274-7 10.7270/Q2Z89DQV Castro, JL; Matassa, VG; Broughton, HB; Mosley, RT; Street, LJ; Baker, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406758&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10401691 163355782 CHEMBL39243 ZINC00014701 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51029611 CN(C)CCc1c[nH]c2ccc(Cc3nc(N)ns3)cc12 InChI=1S/C15H19N5S/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19) BEDGPDAVDXHRMR-UHFFFAOYSA-N 50406762 CHEMBL37462 5-hydroxytryptamine receptor 1D Sus scrofa 2.0 ChEMBL 10.1016/S0960-894X(00)80274-7 10.7270/Q2Z89DQV Castro, JL; Matassa, VG; Broughton, HB; Mosley, RT; Street, LJ; Baker, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406762&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9995045 163355786 CHEMBL37462 ZINC13827497 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51029612 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 1D Sus scrofa 10.0 ChEMBL 10.1016/S0960-894X(00)80274-7 10.7270/Q2Z89DQV Castro, JL; Matassa, VG; Broughton, HB; Mosley, RT; Street, LJ; Baker, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search SRO 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51029613 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1016/S0960-894X(00)80274-7 10.7270/Q2Z89DQV Castro, JL; Matassa, VG; Broughton, HB; Mosley, RT; Street, LJ; Baker, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031817 CN1CCN(Cc2ccc3[nH]cc(CCN)c3c2)S1(=O)=O InChI=1S/C14H20N4O2S/c1-17-6-7-18(21(17,19)20)10-11-2-3-14-13(8-11)12(4-5-15)9-16-14/h2-3,8-9,16H,4-7,10,15H2,1H3 FLHNKTVKQJBVRT-UHFFFAOYSA-N 50422017 CHEMBL103854 5-hydroxytryptamine receptor 1D Sus scrofa 316 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422017&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 11722814 164150892 CHEMBL103854 ZINC00016311 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031820 CN(C)CCc1c[nH]c2ccc(CN3CCN(C)S3(=O)=O)cc12 InChI=1S/C16H24N4O2S/c1-18(2)7-6-14-11-17-16-5-4-13(10-15(14)16)12-20-9-8-19(3)23(20,21)22/h4-5,10-11,17H,6-9,12H2,1-3H3 WZBIUWCSTCPAEF-UHFFFAOYSA-N 50422020 CHEMBL103205 5-hydroxytryptamine receptor 1D Sus scrofa 63 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422020&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9819150 164150895 CHEMBL103205 ZINC00005455 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031824 CN(C)CCc1c[nH]c2ccc(cc12)N1CCN(C)S1(=O)=O InChI=1S/C15H22N4O2S/c1-17(2)7-6-12-11-16-15-5-4-13(10-14(12)15)19-9-8-18(3)22(19,20)21/h4-5,10-11,16H,6-9H2,1-3H3 JHUMJKIZFLOPBI-UHFFFAOYSA-N 50422024 CHEMBL319223 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422024&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10245588 164150899 CHEMBL319223 ZINC13738509 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031825 CN(C)CCc1c[nH]c2ccc(CCN3CCNS3(=O)=O)cc12 InChI=1S/C16H24N4O2S/c1-19(2)8-6-14-12-17-16-4-3-13(11-15(14)16)5-9-20-10-7-18-23(20,21)22/h3-4,11-12,17-18H,5-10H2,1-2H3 MOHPWFHMJJUUSV-UHFFFAOYSA-N 50422021 CHEMBL103549 5-hydroxytryptamine receptor 1D Sus scrofa 40 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422021&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10404770 164150896 CHEMBL103549 ZINC13738517 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031826 CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12 InChI=1S/C17H26N4O2S/c1-19(2)8-7-15-13-18-17-5-4-14(12-16(15)17)6-9-21-11-10-20(3)24(21,22)23/h4-5,12-13,18H,6-11H2,1-3H3 CAYIRJBJYNSWEQ-UHFFFAOYSA-N 50422025 CHEMBL103371 5-hydroxytryptamine receptor 1D Sus scrofa 40 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422025&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10315894 164150900 CHEMBL103371 ZINC00605248 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031827 CC(C)N1CCN(Cc2ccc3[nH]cc(CCN(C)C)c3c2)S1(=O)=O InChI=1S/C18H28N4O2S/c1-14(2)22-10-9-21(25(22,23)24)13-15-5-6-18-17(11-15)16(12-19-18)7-8-20(3)4/h5-6,11-12,14,19H,7-10,13H2,1-4H3 HEFIDNYHXDTDFP-UHFFFAOYSA-N 50422023 CHEMBL318571 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422023&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9998879 164150898 CHEMBL318571 ZINC13738512 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031830 CN(C)CCc1c[nH]c2ccc(CN3CC(C)(C)NS3(=O)=O)cc12 InChI=1S/C17H26N4O2S/c1-17(2)12-21(24(22,23)19-17)11-13-5-6-16-15(9-13)14(10-18-16)7-8-20(3)4/h5-6,9-10,18-19H,7-8,11-12H2,1-4H3 BOFZPIYNCDADLB-UHFFFAOYSA-N 50422026 CHEMBL320412 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422026&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10337965 164150901 CHEMBL320412 ZINC13738515 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031833 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031835 CN(C)CCc1c[nH]c2ccc(CN3CCCN(C)S3(=O)=O)cc12 InChI=1S/C17H26N4O2S/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-21-9-4-8-20(3)24(21,22)23/h5-6,11-12,18H,4,7-10,13H2,1-3H3 QSJGOSBBNCAKJQ-UHFFFAOYSA-N 50422016 CHEMBL323334 5-hydroxytryptamine receptor 1D Sus scrofa 63 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422016&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10043491 164150891 CHEMBL323334 ZINC13738514 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031836 CCN1CCN(CCc2ccc3[nH]cc(CCN(C)C)c3c2)S1(=O)=O InChI=1S/C18H28N4O2S/c1-4-21-11-12-22(25(21,23)24)10-7-15-5-6-18-17(13-15)16(14-19-18)8-9-20(2)3/h5-6,13-14,19H,4,7-12H2,1-3H3 MWQAQKCJKACPMW-UHFFFAOYSA-N 50422019 CHEMBL321963 5-hydroxytryptamine receptor 1D Sus scrofa 40 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422019&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10021702 164150894 CHEMBL321963 ZINC13738518 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031837 CN(C)CCc1c[nH]c2ccc(CN3CCNS3(=O)=O)cc12 InChI=1S/C15H22N4O2S/c1-18(2)7-5-13-10-16-15-4-3-12(9-14(13)15)11-19-8-6-17-22(19,20)21/h3-4,9-10,16-17H,5-8,11H2,1-2H3 UWHVVRIUSATDPT-UHFFFAOYSA-N 50422028 CHEMBL102548 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422028&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10471382 164150903 CHEMBL102548 ZINC13738511 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031838 CN(C)CCc1c[nH]c2ccc(cc12)N1CCN(Cc2ccccc2)S1(=O)=O InChI=1S/C21H26N4O2S/c1-23(2)11-10-18-15-22-21-9-8-19(14-20(18)21)25-13-12-24(28(25,26)27)16-17-6-4-3-5-7-17/h3-9,14-15,22H,10-13,16H2,1-2H3 NFLDDZPDKNUJJZ-UHFFFAOYSA-N 50422022 CHEMBL101138 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422022&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10340828 164150897 CHEMBL101138 ZINC13738510 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031839 CN1CCN(Cc2ccc3scc(CCN)c3c2)S1(=O)=O InChI=1S/C14H19N3O2S2/c1-16-6-7-17(21(16,18)19)9-11-2-3-14-13(8-11)12(4-5-15)10-20-14/h2-3,8,10H,4-7,9,15H2,1H3 QDTMSLOIVPCLDK-UHFFFAOYSA-N 50422027 CHEMBL2111620 5-hydroxytryptamine receptor 1D Sus scrofa 398 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422027&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10404070 164150902 CHEMBL2111620 ZINC13738519 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031840 CN(C)CCc1c[nH]c2ccc(CN3CCN(Cc4ccc(NC(C)=O)cc4)S3(=O)=O)cc12 InChI=1S/C24H31N5O3S/c1-18(30)26-22-7-4-19(5-8-22)16-28-12-13-29(33(28,31)32)17-20-6-9-24-23(14-20)21(15-25-24)10-11-27(2)3/h4-9,14-15,25H,10-13,16-17H2,1-3H3,(H,26,30) HLROMXIAWNSEJU-UHFFFAOYSA-N 50422029 CHEMBL103388 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422029&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10412397 164150904 CHEMBL103388 ZINC00605252 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031841 CN(C)CCc1c[nH]c2ccc(CN3C(C)(C)CNS3(=O)=O)cc12 InChI=1S/C17H26N4O2S/c1-17(2)12-19-24(22,23)21(17)11-13-5-6-16-15(9-13)14(10-18-16)7-8-20(3)4/h5-6,9-10,18-19H,7-8,11-12H2,1-4H3 GNNYKNUIVNJLEO-UHFFFAOYSA-N 50422018 CHEMBL102645 5-hydroxytryptamine receptor 1D Sus scrofa 200 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422018&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10383252 164150893 CHEMBL102645 ZINC13738516 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 51031850 CNCCc1c[nH]c2ccc(CN3CCN(C)S3(=O)=O)cc12 InChI=1S/C15H22N4O2S/c1-16-6-5-13-10-17-15-4-3-12(9-14(13)15)11-19-8-7-18(2)22(19,20)21/h3-4,9-10,16-17H,5-8,11H2,1-2H3 YBKXXWBMSIFLCS-UHFFFAOYSA-N 50422030 CHEMBL102586 5-hydroxytryptamine receptor 1D Sus scrofa 100 ChEMBL 10.1021/jm00045a006 10.7270/Q2V69KWJ 7932524 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Merck Sharp & Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422030&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10471383 164150905 CHEMBL102586 ZINC13738513 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567143 CN(C)CCc1c[nH]c2ccc(cc12)-n1cnnc1 InChI=1S/C14H17N5/c1-18(2)6-5-11-8-15-14-4-3-12(7-13(11)14)19-9-16-17-10-19/h3-4,7-10,15H,5-6H2,1-2H3 IGNXHSPBUUSUHB-UHFFFAOYSA-N 50060426 CHEMBL296161::Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-amine::L-741604 5-hydroxytryptamine receptor 1D Sus scrofa 2 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060426&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9881526 103956189 CHEMBL296161 ZINC00005933 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567156 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 7.7 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567309 CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12 InChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3 ULFRLSNUDGIQQP-UHFFFAOYSA-N 50033437 CHEMBL905::MK 462 free base::N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine::N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine::N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine::RIZATRIPTAN::risatriptan 5-hydroxytryptamine receptor 1D Sus scrofa 16 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033437&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5078 103941727 48273 CHEMBL905 DB00953 51 ZINC00005895 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567339 CN1CCC(CC1)c1c[nH]c2ccc(cc12)-n1cnnc1 InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 VXEWHMQYWRWFDO-UHFFFAOYSA-N 50213961 CHEMBL53739 5-hydroxytryptamine receptor 1D Sus scrofa 8 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213961&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10333932 376071134 CHEMBL53739 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567144 CN1CCC(CC1)c1c[nH]c2ccc(cc12)-n1cnnc1 InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 VXEWHMQYWRWFDO-UHFFFAOYSA-N 50213961 CHEMBL53739 5-hydroxytryptamine receptor 1D Sus scrofa 1.2 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213961&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10333932 376071134 CHEMBL53739 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567148 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 19 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567149 CN(C)CCc1c[nH]c2ccc(cc12)-n1cncn1 InChI=1S/C14H17N5/c1-18(2)6-5-11-8-16-14-4-3-12(7-13(11)14)19-10-15-9-17-19/h3-4,7-10,16H,5-6H2,1-2H3 GKKAQRFMUGUZQS-UHFFFAOYSA-N 50407356 CHEMBL54265 5-hydroxytryptamine receptor 1D Sus scrofa 20 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407356&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 10106412 163356380 CHEMBL54265 ZINC13741364 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567151 CN(C)CCc1c[nH]c2ccc(cc12)-n1cnnc1 InChI=1S/C14H17N5/c1-18(2)6-5-11-8-15-14-4-3-12(7-13(11)14)19-9-16-17-10-19/h3-4,7-10,15H,5-6H2,1-2H3 IGNXHSPBUUSUHB-UHFFFAOYSA-N 50060426 CHEMBL296161::Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-amine::L-741604 5-hydroxytryptamine receptor 1D Sus scrofa 0.430000 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060426&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 9881526 103956189 CHEMBL296161 ZINC00005933 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50567159 CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12 InChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3 ULFRLSNUDGIQQP-UHFFFAOYSA-N 50033437 CHEMBL905::MK 462 free base::N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine::N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine::N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine::RIZATRIPTAN::risatriptan 5-hydroxytryptamine receptor 1D Sus scrofa 49 ChEMBL 10.7270/Q2SX6GDH n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033437&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5078 103941727 48273 CHEMBL905 DB00953 51 ZINC00005895 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50669977 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax 5-hydroxytryptamine receptor 1D Sus scrofa 25 ChEMBL 10.1021/jm00065a015 10.7270/Q2JS9SNZ 8515429 King, FD; Brown, AM; Gaster, LM; Kaumann, AJ; Medhurst, AD; Parker, SG; Parsons, AA; Patch, TL; Raval, P SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400 50670003 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) 5-hydroxytryptamine receptor 1D Sus scrofa 10.0 ChEMBL 10.1021/jm00065a015 10.7270/Q2JS9SNZ 8515429 King, FD; Brown, AM; Gaster, LM; Kaumann, AJ; Medhurst, AD; Parker, SG; Parsons, AA; Patch, TL; Raval, P SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002687&target=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=5-hydroxytryptamine+receptor+1D&column=ki&startPg=0&Increment=50&submit=Search H8G 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV 5-hydroxytryptamine receptor 1D 5HT1D_PIG P79400