BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50046925 Cc1ccccc1Cc1c[nH]c(=O)[nH]c1=O InChI=1S/C12H12N2O2/c1-8-4-2-3-5-9(8)6-10-7-13-12(16)14-11(10)15/h2-5,7H,6H2,1H3,(H2,13,14,15,16) WTJPOYPCNDZAHO-UHFFFAOYSA-N 50030971 5-(2-Methyl-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127393 Uridine phosphorylase 1 Mus musculus 65000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030971&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10376005 103939702 CHEMBL127393 ZINC13743519 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046926 CCC(C)Oc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C18H24N2O5/c1-3-13(2)25-16-6-4-5-14(10-16)9-15-11-20(12-24-8-7-21)18(23)19-17(15)22/h4-6,10-11,13,21H,3,7-9,12H2,1-2H3,(H,19,22,23) QSYHNDCZGFNRHJ-UHFFFAOYSA-N 50030972 5-(3-sec-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL124530 Uridine phosphorylase 1 Mus musculus 27 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030972&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10020654 103939703 CHEMBL124530 ZINC13743506 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046927 COc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1OC InChI=1S/C13H14N2O4/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-14-13(17)15-12(9)16/h3-4,6-7H,5H2,1-2H3,(H2,14,15,16,17) RPPPRGOZIAGTNI-UHFFFAOYSA-N 50030970 5-(3,4-Dimethoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124331 Uridine phosphorylase 1 Mus musculus 129000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030970&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10355328 103939701 CHEMBL124331 ZINC13743524 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046928 Clc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1 InChI=1S/C11H9ClN2O2/c12-9-3-1-7(2-4-9)5-8-6-13-11(16)14-10(8)15/h1-4,6H,5H2,(H2,13,14,15,16) ZAUQWZBGCKEBOG-UHFFFAOYSA-N 50030973 5-(4-Chloro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127127 Uridine phosphorylase 1 Mus musculus 13000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030973&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10105551 103939704 CHEMBL127127 ZINC13743508 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046929 CCCOc1cccc(Cc2cn(COC(CO)CO)c(=O)[nH]c2=O)c1 InChI=1S/C18H24N2O6/c1-2-6-25-15-5-3-4-13(8-15)7-14-9-20(18(24)19-17(14)23)12-26-16(10-21)11-22/h3-5,8-9,16,21-22H,2,6-7,10-12H2,1H3,(H,19,23,24) GFWYTORHRMJMKU-UHFFFAOYSA-N 50030974 1-(2-Hydroxy-1-hydroxymethyl-ethoxymethyl)-5-(3-propoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL125152 Uridine phosphorylase 1 Mus musculus 60 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030974&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 9998846 103939705 CHEMBL125152 ZINC01541373 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046930 OCCOCn1cc(Cc2ccccc2F)c(=O)[nH]c1=O InChI=1S/C14H15FN2O4/c15-12-4-2-1-3-10(12)7-11-8-17(9-21-6-5-18)14(20)16-13(11)19/h1-4,8,18H,5-7,9H2,(H,16,19,20) AITXWLIGNARBHU-UHFFFAOYSA-N 50030975 5-(2-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL128039 Uridine phosphorylase 1 Mus musculus 870.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030975&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10447145 103939706 CHEMBL128039 ZINC13743499 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046931 Cc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1 InChI=1S/C12H12N2O2/c1-8-2-4-9(5-3-8)6-10-7-13-12(16)14-11(10)15/h2-5,7H,6H2,1H3,(H2,13,14,15,16) PIDBIWZWSMEFET-UHFFFAOYSA-N 50030977 5-(4-Methyl-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127467 Uridine phosphorylase 1 Mus musculus 7600 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030977&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10013550 103939708 CHEMBL127467 ZINC13743509 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046932 OCCOCn1cc(Cc2cccc(F)c2)c(=O)[nH]c1=O InChI=1S/C14H15FN2O4/c15-12-3-1-2-10(7-12)6-11-8-17(9-21-5-4-18)14(20)16-13(11)19/h1-3,7-8,18H,4-6,9H2,(H,16,19,20) ZHMNGVLIPCBMMT-UHFFFAOYSA-N 50030976 5-(3-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL125973 Uridine phosphorylase 1 Mus musculus 550 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030976&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10357084 103939707 CHEMBL125973 ZINC13743496 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046933 OCCOCn1cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O InChI=1S/C21H22N2O5/c24-9-10-27-15-23-13-18(20(25)22-21(23)26)11-17-7-4-8-19(12-17)28-14-16-5-2-1-3-6-16/h1-8,12-13,24H,9-11,14-15H2,(H,22,25,26) CSXNPJKDZKLDET-UHFFFAOYSA-N 50030980 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE::5-(3-Benzyloxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL277577 Uridine phosphorylase 1 Mus musculus 84.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030980&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 183 134111 103939711 39579 CHEMBL277577 DB06873 ZINC06096461 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046934 COc1ccccc1Cc1c[nH]c(=O)[nH]c1=O InChI=1S/C12H12N2O3/c1-17-10-5-3-2-4-8(10)6-9-7-13-12(16)14-11(9)15/h2-5,7H,6H2,1H3,(H2,13,14,15,16) NFAGHCRFKVUGGC-UHFFFAOYSA-N 50030978 5-(2-Methoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL434432 Uridine phosphorylase 1 Mus musculus 8200.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030978&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10421443 103939709 CHEMBL434432 ZINC13743520 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046935 COc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1 InChI=1S/C12H12N2O3/c1-17-10-4-2-8(3-5-10)6-9-7-13-12(16)14-11(9)15/h2-5,7H,6H2,1H3,(H2,13,14,15,16) MGBOZHCYSNCCOK-UHFFFAOYSA-N 50030979 5-(4-Methoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124319 Uridine phosphorylase 1 Mus musculus 66500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030979&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 867850 103939710 CHEMBL124319 ZINC05092422 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046936 OCCOCn1cc(Cc2cc(F)cc(F)c2)c(=O)[nH]c1=O InChI=1S/C14H14F2N2O4/c15-11-4-9(5-12(16)6-11)3-10-7-18(8-22-2-1-19)14(21)17-13(10)20/h4-7,19H,1-3,8H2,(H,17,20,21) VBSGPACHJJWZLB-UHFFFAOYSA-N 50030981 5-(3,5-Difluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL340623 Uridine phosphorylase 1 Mus musculus 350 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030981&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10425623 103939712 CHEMBL340623 ZINC13743500 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046937 [O-][N+](=O)c1ccc(Cc2c[n-]c(=[OH+])[nH]c2=O)cc1 InChI=1S/C11H9N3O4/c15-10-8(6-12-11(16)13-10)5-7-1-3-9(4-2-7)14(17)18/h1-4,6H,5H2,(H2,12,13,15,16) BYMQTBCOJXZMED-UHFFFAOYSA-N 50030982 5-(4-Nitro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL340318 Uridine phosphorylase 1 Mus musculus 5900 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030982&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10083298 103939713 CHEMBL340318 ZINC13743510 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046938 OCCOCn1cc(Cc2cccc(OCC=C)c2)c(=O)[nH]c1=O InChI=1S/C17H20N2O5/c1-2-7-24-15-5-3-4-13(10-15)9-14-11-19(12-23-8-6-20)17(22)18-16(14)21/h2-5,10-11,20H,1,6-9,12H2,(H,18,21,22) YKBQQVDSAXEVJT-UHFFFAOYSA-N 50030983 5-(3-Allyloxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL127568 Uridine phosphorylase 1 Mus musculus 130 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030983&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10088126 103939714 CHEMBL127568 ZINC13743503 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046939 OCCOCn1cc(Cc2cccc(Cl)c2)c(=O)[nH]c1=O InChI=1S/C14H15ClN2O4/c15-12-3-1-2-10(7-12)6-11-8-17(9-21-5-4-18)14(20)16-13(11)19/h1-3,7-8,18H,4-6,9H2,(H,16,19,20) NEBAZSCNNDDVJX-UHFFFAOYSA-N 50030984 5-(3-Chloro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL123742 Uridine phosphorylase 1 Mus musculus 300 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030984&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10244911 103939715 CHEMBL123742 ZINC13743497 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046940 C=CCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C14H14N2O3/c1-2-6-19-12-5-3-4-10(8-12)7-11-9-15-14(18)16-13(11)17/h2-5,8-9H,1,6-7H2,(H2,15,16,17,18) FHGWTTHLLPRQKZ-UHFFFAOYSA-N 50030985 5-(3-Allyloxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL125314 Uridine phosphorylase 1 Mus musculus 3600 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030985&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10264482 103939716 CHEMBL125314 ZINC13743528 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046941 Clc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1Cl InChI=1S/C11H8Cl2N2O2/c12-8-2-1-6(4-9(8)13)3-7-5-14-11(17)15-10(7)16/h1-2,4-5H,3H2,(H2,14,15,16,17) TVQFEHRWHVIMSS-UHFFFAOYSA-N 50030986 5-(3,4-Dichloro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL338994 Uridine phosphorylase 1 Mus musculus 15500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030986&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10378466 103939717 CHEMBL338994 ZINC13743523 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046942 CCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C13H14N2O3/c1-2-18-11-5-3-4-9(7-11)6-10-8-14-13(17)15-12(10)16/h3-5,7-8H,2,6H2,1H3,(H2,14,15,16,17) FEOVMWQPLBPEKO-UHFFFAOYSA-N 50030987 5-(3-Ethoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124753 Uridine phosphorylase 1 Mus musculus 2400 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030987&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 309826 103939718 CHEMBL124753 ZINC01750550 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046943 Fc1cc(F)cc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C11H8F2N2O2/c12-8-2-6(3-9(13)4-8)1-7-5-14-11(17)15-10(7)16/h2-5H,1H2,(H2,14,15,16,17) BHDDNVOOBICCPP-UHFFFAOYSA-N 50030988 5-(3,5-Difluoro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL339510 Uridine phosphorylase 1 Mus musculus 7600 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030988&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10037196 103939719 CHEMBL339510 ZINC13743522 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046944 Clc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C11H9ClN2O2/c12-9-3-1-2-7(5-9)4-8-6-13-11(16)14-10(8)15/h1-3,5-6H,4H2,(H2,13,14,15,16) CSWPPKCYKLBTJX-UHFFFAOYSA-N 50030989 5-(3-Chloro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL339101 Uridine phosphorylase 1 Mus musculus 2500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030989&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10399246 103939720 CHEMBL339101 ZINC13743513 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046945 OCCOCn1cc(Cc2cccc(OCCCF)c2)c(=O)[nH]c1=O InChI=1S/C17H21FN2O5/c18-5-2-7-25-15-4-1-3-13(10-15)9-14-11-20(12-24-8-6-21)17(23)19-16(14)22/h1,3-4,10-11,21H,2,5-9,12H2,(H,19,22,23) APGFFBHJDGIFJW-UHFFFAOYSA-N 50030990 5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL126468 Uridine phosphorylase 1 Mus musculus 68.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030990&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10043575 103939721 CHEMBL126468 ZINC01541371 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046946 CC(C)Oc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C14H16N2O3/c1-9(2)19-12-5-3-4-10(7-12)6-11-8-15-14(18)16-13(11)17/h3-5,7-9H,6H2,1-2H3,(H2,15,16,17,18) DIMYXXIOIWXKSG-UHFFFAOYSA-N 50030992 5-(3-Isopropoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127209 Uridine phosphorylase 1 Mus musculus 2000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030992&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10083951 103939723 CHEMBL127209 ZINC13743527 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046947 FC(F)(F)CCCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C15H15F3N2O3/c16-15(17,18)5-2-6-23-12-4-1-3-10(8-12)7-11-9-19-14(22)20-13(11)21/h1,3-4,8-9H,2,5-7H2,(H2,19,20,21,22) NCTCMHSWZNKCME-UHFFFAOYSA-N 50030993 5-[3-(4,4,4-Trifluoro-butoxy)-benzyl]-1H-pyrimidine-2,4-dione::CHEMBL127375 Uridine phosphorylase 1 Mus musculus 13000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030993&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10042132 103939724 CHEMBL127375 ZINC13743534 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046948 Cc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C12H12N2O2/c1-8-3-2-4-9(5-8)6-10-7-13-12(16)14-11(10)15/h2-5,7H,6H2,1H3,(H2,13,14,15,16) IKACPHWNZGKFID-UHFFFAOYSA-N 50030991 5-(3-Methyl-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124641 Uridine phosphorylase 1 Mus musculus 8500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030991&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 11820615 103939722 CHEMBL124641 ZINC13743515 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046949 CCCCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C18H24N2O5/c1-2-3-8-25-16-6-4-5-14(11-16)10-15-12-20(13-24-9-7-21)18(23)19-17(15)22/h4-6,11-12,21H,2-3,7-10,13H2,1H3,(H,19,22,23) XJVHEQVQHPSZGU-UHFFFAOYSA-N 50030995 5-(3-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL123971 Uridine phosphorylase 1 Mus musculus 160 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030995&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10405457 103939726 CHEMBL123971 ZINC13743505 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046950 O=c1[nH]cc(Cc2ccc3OCOc3c2)c(=O)[nH]1 InChI=1S/C12H10N2O4/c15-11-8(5-13-12(16)14-11)3-7-1-2-9-10(4-7)18-6-17-9/h1-2,4-5H,3,6H2,(H2,13,14,15,16) XXHWOENZMHTWGE-UHFFFAOYSA-N 50030994 5-Benzo[1,3]dioxol-5-ylmethyl-1H-pyrimidine-2,4-dione::CHEMBL124537 Uridine phosphorylase 1 Mus musculus 13600 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030994&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10105945 103939725 CHEMBL124537 ZINC13743525 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046951 O=c1[nH]cc(Cc2ccccc2)c(=O)[nH]1 InChI=1S/C11H10N2O2/c14-10-9(7-12-11(15)13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,12,13,14,15) RPZOVLGFKOOIRP-UHFFFAOYSA-N 50030998 5-Benzyl-1H-pyrimidine-2,4-dione::CHEMBL275965 Uridine phosphorylase 1 Mus musculus 5700 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030998&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 236212 103939729 CHEMBL275965 ZINC01670654 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046952 COc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C12H12N2O3/c1-17-10-4-2-3-8(6-10)5-9-7-13-12(16)14-11(9)15/h2-4,6-7H,5H2,1H3,(H2,13,14,15,16) NOFPXZXTKXPRDN-UHFFFAOYSA-N 50030997 5-(3-Methoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL446113 Uridine phosphorylase 1 Mus musculus 3900 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030997&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 309840 103939728 CHEMBL446113 ZINC01750584 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046953 OCC(CO)OCn1cc(Cc2cccc(Cl)c2)c(=O)[nH]c1=O InChI=1S/C15H17ClN2O5/c16-12-3-1-2-10(5-12)4-11-6-18(15(22)17-14(11)21)9-23-13(7-19)8-20/h1-3,5-6,13,19-20H,4,7-9H2,(H,17,21,22) FEOVRKPROCUWHY-UHFFFAOYSA-N 50030999 5-(3-Chloro-benzyl)-1-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL126752 Uridine phosphorylase 1 Mus musculus 110 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030999&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 11724849 103939730 CHEMBL126752 ZINC13743498 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046954 Fc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1 InChI=1S/C11H9FN2O2/c12-9-3-1-7(2-4-9)5-8-6-13-11(16)14-10(8)15/h1-4,6H,5H2,(H2,13,14,15,16) DVYBVUXNBSGNGM-UHFFFAOYSA-N 50030996 5-(4-Fluoro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127536 Uridine phosphorylase 1 Mus musculus 16400 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030996&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10443433 103939727 CHEMBL127536 ZINC13743507 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046955 CCCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C17H22N2O5/c1-2-7-24-15-5-3-4-13(10-15)9-14-11-19(12-23-8-6-20)17(22)18-16(14)21/h3-5,10-11,20H,2,6-9,12H2,1H3,(H,18,21,22) DXUZJGHBPUXUEL-UHFFFAOYSA-N 50031005 1-(2-Hydroxy-ethoxymethyl)-5-(3-propoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL123799 Uridine phosphorylase 1 Mus musculus 47 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031005&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10472053 103939736 CHEMBL123799 ZINC01541372 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046956 CCCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C14H16N2O3/c1-2-6-19-12-5-3-4-10(8-12)7-11-9-15-14(18)16-13(11)17/h3-5,8-9H,2,6-7H2,1H3,(H2,15,16,17,18) DCOWRPQOIGKDAP-UHFFFAOYSA-N 50031001 5-(3-Propoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124639 Uridine phosphorylase 1 Mus musculus 840.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031001&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 9992761 103939732 CHEMBL124639 ZINC13743526 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046957 CC(C)Oc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C17H22N2O5/c1-12(2)24-15-5-3-4-13(9-15)8-14-10-19(11-23-7-6-20)17(22)18-16(14)21/h3-5,9-10,12,20H,6-8,11H2,1-2H3,(H,18,21,22) DCMRPHQMVPBKOO-UHFFFAOYSA-N 50031004 1-(2-Hydroxy-ethoxymethyl)-5-(3-isopropoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL419788 Uridine phosphorylase 1 Mus musculus 160 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031004&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 11724432 103939735 CHEMBL419788 ZINC13743502 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046958 CCC(C)Oc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C15H18N2O3/c1-3-10(2)20-13-6-4-5-11(8-13)7-12-9-16-15(19)17-14(12)18/h4-6,8-10H,3,7H2,1-2H3,(H2,16,17,18,19) VXLKLBJWLOIORX-UHFFFAOYSA-N 50031000 5-(3-sec-Butoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL339247 Uridine phosphorylase 1 Mus musculus 1100 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031000&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10265356 103939731 CHEMBL339247 ZINC13743532 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046959 Fc1ccccc1Cc1c[nH]c(=O)[nH]c1=O InChI=1S/C11H9FN2O2/c12-9-4-2-1-3-7(9)5-8-6-13-11(16)14-10(8)15/h1-4,6H,5H2,(H2,13,14,15,16) VVFCNHBKSYECOR-UHFFFAOYSA-N 50031008 5-(2-Fluoro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124016 Uridine phosphorylase 1 Mus musculus 4000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031008&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10059301 103939739 CHEMBL124016 ZINC13743517 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046960 CC(C)COc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C15H18N2O3/c1-10(2)9-20-13-5-3-4-11(7-13)6-12-8-16-15(19)17-14(12)18/h3-5,7-8,10H,6,9H2,1-2H3,(H2,16,17,18,19) MRCCGIRAFZRCKD-UHFFFAOYSA-N 50031002 5-(3-Isobutoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127247 Uridine phosphorylase 1 Mus musculus 1400 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031002&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10333549 103939733 CHEMBL127247 ZINC13743533 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046961 CCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C16H20N2O5/c1-2-23-14-5-3-4-12(9-14)8-13-10-18(11-22-7-6-19)16(21)17-15(13)20/h3-5,9-10,19H,2,6-8,11H2,1H3,(H,17,20,21) XYDCUDXJNVWIFC-UHFFFAOYSA-N 50031006 5-(3-Ethoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL127250 Uridine phosphorylase 1 Mus musculus 100 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031006&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10041678 103939737 CHEMBL127250 ZINC13743501 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046962 OCC(CO)OCn1cc(Cc2cccc(OCCCF)c2)c(=O)[nH]c1=O InChI=1S/C18H23FN2O6/c19-5-2-6-26-15-4-1-3-13(8-15)7-14-9-21(18(25)20-17(14)24)12-27-16(10-22)11-23/h1,3-4,8-9,16,22-23H,2,5-7,10-12H2,(H,20,24,25) DQDHGOKDAJBXQY-UHFFFAOYSA-N 50031007 5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL125136 Uridine phosphorylase 1 Mus musculus 110 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031007&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10362469 103939738 CHEMBL125136 ZINC13743504 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046963 O=c1[nH]cc(Cc2ccc(cc2)C#N)c(=O)[nH]1 InChI=1S/C12H9N3O2/c13-6-9-3-1-8(2-4-9)5-10-7-14-12(17)15-11(10)16/h1-4,7H,5H2,(H2,14,15,16,17) OEPKHDANZVHOBB-UHFFFAOYSA-N 50031003 4-(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-benzonitrile::CHEMBL124860 Uridine phosphorylase 1 Mus musculus 21100 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031003&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10082445 103939734 CHEMBL124860 ZINC13743511 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046964 O=c1[nH]cc(Cc2cccc(c2)C#N)c(=O)[nH]1 InChI=1S/C12H9N3O2/c13-6-9-3-1-2-8(4-9)5-10-7-14-12(17)15-11(10)16/h1-4,7H,5H2,(H2,14,15,16,17) AGTNEKGESIVZAZ-UHFFFAOYSA-N 50031014 3-(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-benzonitrile::CHEMBL124640 Uridine phosphorylase 1 Mus musculus 13200 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031014&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10082446 103939745 CHEMBL124640 ZINC13743516 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046965 Fc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C11H9FN2O2/c12-9-3-1-2-7(5-9)4-8-6-13-11(16)14-10(8)15/h1-3,5-6H,4H2,(H2,13,14,15,16) CBKNUEKHNYDAGI-UHFFFAOYSA-N 50031013 5-(3-Fluoro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL126531 Uridine phosphorylase 1 Mus musculus 7600 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031013&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10443434 103939744 CHEMBL126531 ZINC13743512 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046966 CC(C)COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C18H24N2O5/c1-13(2)11-25-16-5-3-4-14(9-16)8-15-10-20(12-24-7-6-21)18(23)19-17(15)22/h3-5,9-10,13,21H,6-8,11-12H2,1-2H3,(H,19,22,23) AXDCZCJENGHNOG-UHFFFAOYSA-N 50031009 1-(2-Hydroxy-ethoxymethyl)-5-(3-isobutoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL445839 Uridine phosphorylase 1 Mus musculus 66.0 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031009&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10427831 103939740 CHEMBL445839 ZINC01541374 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046967 COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 InChI=1S/C15H18N2O5/c1-21-13-4-2-3-11(8-13)7-12-9-17(10-22-6-5-18)15(20)16-14(12)19/h2-4,8-9,18H,5-7,10H2,1H3,(H,16,19,20) NATVNSLPKFUVIT-UHFFFAOYSA-N 50031010 1-(2-Hydroxy-ethoxymethyl)-5-(3-methoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL123683 Uridine phosphorylase 1 Mus musculus 1860 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031010&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 15209348 103939741 CHEMBL123683 ZINC27216597 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046968 FCCCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C14H15FN2O3/c15-5-2-6-20-12-4-1-3-10(8-12)7-11-9-16-14(19)17-13(11)18/h1,3-4,8-9H,2,5-7H2,(H2,16,17,18,19) SUWSPAPWGVKBJL-UHFFFAOYSA-N 50031012 5-[3-(3-Fluoro-propoxy)-benzyl]-1H-pyrimidine-2,4-dione::CHEMBL124645 Uridine phosphorylase 1 Mus musculus 1500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031012&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10107578 103939743 CHEMBL124645 ZINC13743529 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046969 OCCOCn1cc(Cc2ccccc2)c(=O)[nH]c1=O InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19) SPJAGILXQBHHSZ-UHFFFAOYSA-N 50026387 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE::5-Benzyl-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL17432 Uridine phosphorylase 1 Mus musculus 460 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026387&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search BAU 54929 103936065 41037 CHEMBL17432 DB07437 ZINC02021810 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046970 CCCCOc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C15H18N2O3/c1-2-3-7-20-13-6-4-5-11(9-13)8-12-10-16-15(19)17-14(12)18/h4-6,9-10H,2-3,7-8H2,1H3,(H2,16,17,18,19) FMQFEFYXQLCFBI-UHFFFAOYSA-N 50031011 5-(3-Butoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL123520 Uridine phosphorylase 1 Mus musculus 8500 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031011&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 11778100 103939742 CHEMBL123520 ZINC13743530 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046971 Fc1ccc(Cc2c[nH]c(=O)[nH]c2=O)cc1F InChI=1S/C11H8F2N2O2/c12-8-2-1-6(4-9(8)13)3-7-5-14-11(17)15-10(7)16/h1-2,4-5H,3H2,(H2,14,15,16,17) BDZPKBIPJPIKBT-UHFFFAOYSA-N 50031016 5-(3,4-Difluoro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127070 Uridine phosphorylase 1 Mus musculus 25000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031016&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10105598 103939747 CHEMBL127070 ZINC13743521 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046972 FC(F)(F)c1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1 InChI=1S/C12H9F3N2O2/c13-12(14,15)9-3-1-2-7(5-9)4-8-6-16-11(19)17-10(8)18/h1-3,5-6H,4H2,(H2,16,17,18,19) XDUHUYVYWKHPRJ-UHFFFAOYSA-N 50031015 5-(3-Trifluoromethyl-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL124397 Uridine phosphorylase 1 Mus musculus 21400 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031015&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10107145 103939746 CHEMBL124397 ZINC13743514 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0 50046973 Clc1ccccc1Cc1c[nH]c(=O)[nH]c1=O InChI=1S/C11H9ClN2O2/c12-9-4-2-1-3-7(9)5-8-6-13-11(16)14-10(8)15/h1-4,6H,5H2,(H2,13,14,15,16) CPQAZTSRWAQRAQ-UHFFFAOYSA-N 50031017 5-(2-Chloro-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127529 Uridine phosphorylase 1 Mus musculus 24000 ChEMBL 10.1021/jm00019a015 10.7270/Q2B27T91 7562916 Orr, GF; Musso, DL; Boswell, GE; Kelley, JL; Joyner, SS; Davis, ST; Baccanari, DP Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002545&target=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031017&enzyme=Uridine+phosphorylase+1&column=ki&startPg=0&Increment=50&submit=Search 10354131 103939748 CHEMBL127529 ZINC13743518 1 MAATGTEAKDLENHHNDCFIQLSNPNIAAMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSSRMNTFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLYHARCSNITIIRIGTSGGIGLEPGSVVITQQAVNECFKPEFEQIVLGKRVIRNTNLDAQLVQELVQCSSDLNEFPMVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQSYLRAAHAAGVRNIEMESSVFATMCSACGLKAAVVCVTLLDRLQGDQINTPHDVLVEYQQRPQRLVGHFIKKSLGRA Uridine phosphorylase 1 UPP1_MOUSE P52624 Q8JZX0