BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50231851 COc1cnc2ccc(=O)n(C[C@H](N)[C@H]3CC[C@@H](CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1 InChI=1S/C25H30N6O4/c1-34-18-10-21-20(28-12-18)7-9-24(33)31(21)13-19(26)15-2-4-16(5-3-15)27-11-17-6-8-22-25(29-17)30-23(32)14-35-22/h6-10,12,15-16,19,27H,2-5,11,13-14,26H2,1H3,(H,29,30,32)/t15-,16-,19-/m0/s1 HXCSDXBLCTUKEB-BXWFABGCSA-N 50023582 CHEMBL3355575 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >333000 ChEMBL 10.1016/j.bmc.2014.07.040 10.7270/Q2VQ3480 25155913 Reck, F; Ehmann, DE; Dougherty, TJ; Newman, JV; Hopkins, S; Stone, G; Agrawal, N; Ciaccio, P; McNulty, J; Barthlow, H; O'Donnell, J; Goteti, K; Breen, J; Comita-Prevoir, J; Cornebise, M; Cronin, M; Eyermann, CJ; Geng, B; Carr, GR; Pandarinathan, L; Tang, X; Cottone, A; Zhao, L; Bezdenejnih-Snyder, N AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023582&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 46205341 313064693 CHEMBL3355575 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50231870 COc1ccc2ncc(=O)n(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1 InChI=1S/C24H28N6O4/c1-33-18-3-4-19-20(12-18)30(23(32)14-26-19)11-10-29-8-6-16(7-9-29)25-13-17-2-5-21-24(27-17)28-22(31)15-34-21/h2-5,12,14,16,25H,6-11,13,15H2,1H3,(H,27,28,31) VQECILSOQQFMKP-UHFFFAOYSA-N 50395399 CHEMBL2165063 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 35000 ChEMBL 10.1016/j.bmc.2014.07.040 10.7270/Q2VQ3480 25155913 Reck, F; Ehmann, DE; Dougherty, TJ; Newman, JV; Hopkins, S; Stone, G; Agrawal, N; Ciaccio, P; McNulty, J; Barthlow, H; O'Donnell, J; Goteti, K; Breen, J; Comita-Prevoir, J; Cornebise, M; Cronin, M; Eyermann, CJ; Geng, B; Carr, GR; Pandarinathan, L; Tang, X; Cottone, A; Zhao, L; Bezdenejnih-Snyder, N AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395399&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 15982534 163344423 CHEMBL2165063 ZINC34844399 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50231884 N[C@@H](Cn1c2cc(F)ccc2ncc1=O)[C@H]1CC[C@@H](CC1)NCc1ncc2OCC(=O)Nc2n1 InChI=1S/C23H26FN7O3/c24-14-3-6-17-18(7-14)31(22(33)10-27-17)11-16(25)13-1-4-15(5-2-13)26-9-20-28-8-19-23(29-20)30-21(32)12-34-19/h3,6-8,10,13,15-16,26H,1-2,4-5,9,11-12,25H2,(H,28,29,30,32)/t13-,15-,16-/m0/s1 PIVJTBXDGKAQQI-BPUTZDHNSA-N 50023589 CHEMBL3355573 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >333000 ChEMBL 10.1016/j.bmc.2014.07.040 10.7270/Q2VQ3480 25155913 Reck, F; Ehmann, DE; Dougherty, TJ; Newman, JV; Hopkins, S; Stone, G; Agrawal, N; Ciaccio, P; McNulty, J; Barthlow, H; O'Donnell, J; Goteti, K; Breen, J; Comita-Prevoir, J; Cornebise, M; Cronin, M; Eyermann, CJ; Geng, B; Carr, GR; Pandarinathan, L; Tang, X; Cottone, A; Zhao, L; Bezdenejnih-Snyder, N AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023589&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 46206000 313064700 CHEMBL3355573 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50628582 Fc1cc(c(Cl)nc1Cl)-c1cc(=O)n2[nH]c(c(-c3ccccc3)c2n1)C(F)(F)F InChI=1S/C18H8Cl2F4N4O/c19-15-9(6-10(21)16(20)26-15)11-7-12(29)28-17(25-11)13(8-4-2-1-3-5-8)14(27-28)18(22,23)24/h1-7,27H ZOLHKPWSDFSDKA-UHFFFAOYSA-N 50339281 5-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL1689654 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 49290 ChEMBL 10.1016/j.ejmech.2011.01.010 10.7270/Q2TM7BDF 21296466 Qi, J; Zhang, F; Mi, Y; Fu, Y; Xu, W; Zhang, D; Wu, Y; Du, X; Jia, Q; Wang, K; Zhang, H Hebei Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339281&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 51351551 125089383 CHEMBL1689654 ZINC66123484 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50803730 COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1 HXTGXYRHXAGCFP-OAQYLSRUSA-N 50095027 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)::(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)::(R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::(R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol::CHEMBL74355::MDL 100907::MDL-100907 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1060 ChEMBL 10.1021/jm0002432 10.7270/Q24Q7VQH 11170639 Rowley, M; Bristow, LJ; Hutson, PH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095027&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 5311271 103992797 CHEMBL74355 185 ZINC00598040 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952411 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(cc2)C(F)(F)F)n1 InChI=1S/C23H22F3N3O4S2/c1-33-17-9-5-15(6-10-17)19-14-34-22(27-19)28-21(30)20-4-2-3-13-29(20)35(31,32)18-11-7-16(8-12-18)23(24,25)26/h5-12,14,20H,2-4,13H2,1H3,(H,27,28,30)/t20-/m1/s1 OYZFDCRKHSVNLX-HXUWFJFHSA-N 50390867 CHEMBL2070959 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1710 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390867&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347906 160869950 CHEMBL2070959 ZINC84690512 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952412 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2OC)n1 InChI=1S/C23H25N3O5S2/c1-30-17-12-10-16(11-13-17)18-15-32-23(24-18)25-22(27)19-7-5-6-14-26(19)33(28,29)21-9-4-3-8-20(21)31-2/h3-4,8-13,15,19H,5-7,14H2,1-2H3,(H,24,25,27)/t19-/m1/s1 YIFQKULQCOOZBS-LJQANCHMSA-N 50390868 CHEMBL2070960 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1780 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390868&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347924 160869951 CHEMBL2070960 ZINC84690513 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952413 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(OC)c2)n1 InChI=1S/C23H25N3O5S2/c1-30-17-11-9-16(10-12-17)20-15-32-23(24-20)25-22(27)21-8-3-4-13-26(21)33(28,29)19-7-5-6-18(14-19)31-2/h5-7,9-12,14-15,21H,3-4,8,13H2,1-2H3,(H,24,25,27)/t21-/m1/s1 IWCFXTOKWYWHGJ-OAQYLSRUSA-N 50390869 CHEMBL2070961 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 810 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390869&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347930 160869952 CHEMBL2070961 ZINC84690514 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952414 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc3OCOc3c2)n1 InChI=1S/C23H23N3O6S2/c1-30-16-7-5-15(6-8-16)18-13-33-23(24-18)25-22(27)19-4-2-3-11-26(19)34(28,29)17-9-10-20-21(12-17)32-14-31-20/h5-10,12-13,19H,2-4,11,14H2,1H3,(H,24,25,27)/t19-/m1/s1 DBBOQJMMLCGLIJ-LJQANCHMSA-N 50390870 CHEMBL2070962 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 780 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390870&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488284 160869953 CHEMBL2070962 ZINC84690515 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952415 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2C#N)n1 InChI=1S/C23H22N4O4S2/c1-31-18-11-9-16(10-12-18)19-15-32-23(25-19)26-22(28)20-7-4-5-13-27(20)33(29,30)21-8-3-2-6-17(21)14-24/h2-3,6,8-12,15,20H,4-5,7,13H2,1H3,(H,25,26,28)/t20-/m1/s1 YSTDPMOQUXAVIL-HXUWFJFHSA-N 50390871 CHEMBL2070963 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390871&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347914 160869954 CHEMBL2070963 ZINC84889633 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952416 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(c2)C#N)n1 InChI=1S/C23H22N4O4S2/c1-31-18-10-8-17(9-11-18)20-15-32-23(25-20)26-22(28)21-7-2-3-12-27(21)33(29,30)19-6-4-5-16(13-19)14-24/h4-6,8-11,13,15,21H,2-3,7,12H2,1H3,(H,25,26,28)/t21-/m1/s1 MFCYHGFONMEMKY-OAQYLSRUSA-N 50390872 CHEMBL2070964 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 880 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390872&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347932 160869955 CHEMBL2070964 ZINC84687105 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952417 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(cc2)C#N)n1 InChI=1S/C23H22N4O4S2/c1-31-18-9-7-17(8-10-18)20-15-32-23(25-20)26-22(28)21-4-2-3-13-27(21)33(29,30)19-11-5-16(14-24)6-12-19/h5-12,15,21H,2-4,13H2,1H3,(H,25,26,28)/t21-/m1/s1 IUQJFYIXPYOHPS-OAQYLSRUSA-N 50390873 CHEMBL2070965 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1630 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390873&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488280 160869956 CHEMBL2070965 ZINC84687106 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952418 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(F)c2)n1 InChI=1S/C22H22FN3O4S2/c1-30-17-10-8-15(9-11-17)19-14-31-22(24-19)25-21(27)20-7-2-3-12-26(20)32(28,29)18-6-4-5-16(23)13-18/h4-6,8-11,13-14,20H,2-3,7,12H2,1H3,(H,24,25,27)/t20-/m1/s1 LGOFGFAWDWWMFQ-HXUWFJFHSA-N 50390874 CHEMBL2070966 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1160 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390874&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347890 160869957 CHEMBL2070966 ZINC84687107 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952419 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(F)cc2)n1 InChI=1S/C22H22FN3O4S2/c1-30-17-9-5-15(6-10-17)19-14-31-22(24-19)25-21(27)20-4-2-3-13-26(20)32(28,29)18-11-7-16(23)8-12-18/h5-12,14,20H,2-4,13H2,1H3,(H,24,25,27)/t20-/m1/s1 BQOBEPWVFRLATF-HXUWFJFHSA-N 50390875 CHEMBL2070967 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1030 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390875&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347916 160869958 CHEMBL2070967 ZINC84687108 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952420 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2Cl)n1 InChI=1S/C22H22ClN3O4S2/c1-30-16-11-9-15(10-12-16)18-14-31-22(24-18)25-21(27)19-7-4-5-13-26(19)32(28,29)20-8-3-2-6-17(20)23/h2-3,6,8-12,14,19H,4-5,7,13H2,1H3,(H,24,25,27)/t19-/m1/s1 BRKBEIHVTHJZIV-LJQANCHMSA-N 50390876 CHEMBL2070968 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 730 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390876&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765382 160869959 CHEMBL2070968 ZINC84672373 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952421 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(Cl)c2)n1 InChI=1S/C22H22ClN3O4S2/c1-30-17-10-8-15(9-11-17)19-14-31-22(24-19)25-21(27)20-7-2-3-12-26(20)32(28,29)18-6-4-5-16(23)13-18/h4-6,8-11,13-14,20H,2-3,7,12H2,1H3,(H,24,25,27)/t20-/m1/s1 IPKMZSHOFPYGGZ-HXUWFJFHSA-N 50390877 CHEMBL2070969 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1410 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390877&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347896 160869960 CHEMBL2070969 ZINC84726880 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952422 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(Cl)cc2)n1 InChI=1S/C22H22ClN3O4S2/c1-30-17-9-5-15(6-10-17)19-14-31-22(24-19)25-21(27)20-4-2-3-13-26(20)32(28,29)18-11-7-16(23)8-12-18/h5-12,14,20H,2-4,13H2,1H3,(H,24,25,27)/t20-/m1/s1 DEOZIKXLNMNPAG-HXUWFJFHSA-N 50390878 CHEMBL2070970 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 420 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390878&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347918 160869961 CHEMBL2070970 ZINC84726885 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952423 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(Cl)c2Cl)n1 InChI=1S/C22H21Cl2N3O4S2/c1-31-15-10-8-14(9-11-15)17-13-32-22(25-17)26-21(28)18-6-2-3-12-27(18)33(29,30)19-7-4-5-16(23)20(19)24/h4-5,7-11,13,18H,2-3,6,12H2,1H3,(H,25,26,28)/t18-/m1/s1 MCTYTYQVRWNKKQ-GOSISDBHSA-N 50390879 CHEMBL2070971 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390879&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765451 160869962 CHEMBL2070971 ZINC84726891 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952424 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(F)cc2Cl)n1 InChI=1S/C22H21ClFN3O4S2/c1-31-16-8-5-14(6-9-16)18-13-32-22(25-18)26-21(28)19-4-2-3-11-27(19)33(29,30)20-10-7-15(24)12-17(20)23/h5-10,12-13,19H,2-4,11H2,1H3,(H,25,26,28)/t19-/m1/s1 ZIYSRDSGXNYWPE-LJQANCHMSA-N 50390880 CHEMBL2070972 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390880&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765450 160869963 CHEMBL2070972 ZINC84910563 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952425 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cc(Cl)ccc2F)n1 InChI=1S/C22H21ClFN3O4S2/c1-31-16-8-5-14(6-9-16)18-13-32-22(25-18)26-21(28)19-4-2-3-11-27(19)33(29,30)20-12-15(23)7-10-17(20)24/h5-10,12-13,19H,2-4,11H2,1H3,(H,25,26,28)/t19-/m1/s1 KTRRTYCMMYVRAA-LJQANCHMSA-N 50390881 CHEMBL2070973 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390881&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347892 160869964 CHEMBL2070973 ZINC84728325 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952426 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(F)c2C)n1 InChI=1S/C23H24FN3O4S2/c1-15-18(24)6-5-8-21(15)33(29,30)27-13-4-3-7-20(27)22(28)26-23-25-19(14-32-23)16-9-11-17(31-2)12-10-16/h5-6,8-12,14,20H,3-4,7,13H2,1-2H3,(H,25,26,28)/t20-/m1/s1 WHOPQTXSWWLKRU-HXUWFJFHSA-N 50390882 CHEMBL2070974 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390882&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347912 160869965 CHEMBL2070974 ZINC84728331 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952427 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)Cc2ccccc2Cl)n1 InChI=1S/C23H24ClN3O4S2/c1-31-18-11-9-16(10-12-18)20-14-32-23(25-20)26-22(28)21-8-4-5-13-27(21)33(29,30)15-17-6-2-3-7-19(17)24/h2-3,6-7,9-12,14,21H,4-5,8,13,15H2,1H3,(H,25,26,28)/t21-/m1/s1 KPLDONHGEUOGJI-OAQYLSRUSA-N 50390883 CHEMBL2070975 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390883&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347908 160869966 CHEMBL2070975 ZINC84671964 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952428 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)Cc2ccc(Cl)cc2)n1 InChI=1S/C23H24ClN3O4S2/c1-31-19-11-7-17(8-12-19)20-14-32-23(25-20)26-22(28)21-4-2-3-13-27(21)33(29,30)15-16-5-9-18(24)10-6-16/h5-12,14,21H,2-4,13,15H2,1H3,(H,25,26,28)/t21-/m1/s1 JPZRKGHLOXQCMD-OAQYLSRUSA-N 50390884 CHEMBL2070976 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390884&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347910 160869967 CHEMBL2070976 ZINC84688506 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952429 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2nccc3ccccc23)n1 InChI=1S/C25H24N4O4S2/c1-33-19-11-9-18(10-12-19)21-16-34-25(27-21)28-23(30)22-8-4-5-15-29(22)35(31,32)24-20-7-3-2-6-17(20)13-14-26-24/h2-3,6-7,9-14,16,22H,4-5,8,15H2,1H3,(H,27,28,30)/t22-/m1/s1 NTOCWVFCKNJPJO-JOCHJYFZSA-N 50390885 CHEMBL2070977 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 7970 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390885&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347898 160869968 CHEMBL2070977 ZINC84688507 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952430 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccnc2)n1 InChI=1S/C21H22N4O4S2/c1-29-16-9-7-15(8-10-16)18-14-30-21(23-18)24-20(26)19-6-2-3-12-25(19)31(27,28)17-5-4-11-22-13-17/h4-5,7-11,13-14,19H,2-3,6,12H2,1H3,(H,23,24,26)/t19-/m1/s1 SDELEDYMMRUSJK-LJQANCHMSA-N 50390886 CHEMBL2070978 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1360 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390886&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347900 160869969 CHEMBL2070978 ZINC84688508 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952431 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cn(C)cn2)n1 InChI=1S/C20H23N5O4S2/c1-24-11-18(21-13-24)31(27,28)25-10-4-3-5-17(25)19(26)23-20-22-16(12-30-20)14-6-8-15(29-2)9-7-14/h6-9,11-13,17H,3-5,10H2,1-2H3,(H,22,23,26)/t17-/m1/s1 SKGWPMOJLSALPR-QGZVFWFLSA-N 50390887 CHEMBL2070979 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390887&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765449 160869970 CHEMBL2070979 ZINC84688509 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952432 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccnc2C)n1 InChI=1S/C22H24N4O4S2/c1-15-20(7-5-12-23-15)32(28,29)26-13-4-3-6-19(26)21(27)25-22-24-18(14-31-22)16-8-10-17(30-2)11-9-16/h5,7-12,14,19H,3-4,6,13H2,1-2H3,(H,24,25,27)/t19-/m1/s1 IEUGVYBSSQJRAK-LJQANCHMSA-N 50390888 CHEMBL2070980 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390888&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765453 160869971 CHEMBL2070980 ZINC84688510 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952433 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2C(=O)c2ccccc2)n1 InChI=1S/C23H23N3O3S/c1-29-18-12-10-16(11-13-18)19-15-30-23(24-19)25-21(27)20-9-5-6-14-26(20)22(28)17-7-3-2-4-8-17/h2-4,7-8,10-13,15,20H,5-6,9,14H2,1H3,(H,24,25,27)/t20-/m1/s1 CBTUUEQSTWLERG-HXUWFJFHSA-N 50390889 CHEMBL2070982 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 8160 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390889&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347922 160869972 CHEMBL2070982 ZINC84689737 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952434 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2C(=O)c2ccccc2OC)n1 InChI=1S/C24H25N3O4S/c1-30-17-12-10-16(11-13-17)19-15-32-24(25-19)26-22(28)20-8-5-6-14-27(20)23(29)18-7-3-4-9-21(18)31-2/h3-4,7,9-13,15,20H,5-6,8,14H2,1-2H3,(H,25,26,28)/t20-/m1/s1 BLXBGGFWFCFTDM-HXUWFJFHSA-N 50390890 CHEMBL2070983 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390890&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347928 160869973 CHEMBL2070983 ZINC84689739 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952435 COc1ccc(cc1)-c1csc(NC(=O)C2CCCCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C24H27N3O4S2/c1-17-7-13-20(14-8-17)33(29,30)27-15-5-3-4-6-22(27)23(28)26-24-25-21(16-32-24)18-9-11-19(31-2)12-10-18/h7-14,16,22H,3-6,15H2,1-2H3,(H,25,26,28) NPKOBKJPUACFER-UHFFFAOYSA-N 50390891 CHEMBL2070984 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390891&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765378 160869974 CHEMBL2070984 ZINC84689220 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952436 COc1ccc(cc1)-c1csc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C22H23N3O4S2/c1-15-5-11-18(12-6-15)31(27,28)25-13-3-4-20(25)21(26)24-22-23-19(14-30-22)16-7-9-17(29-2)10-8-16/h5-12,14,20H,3-4,13H2,1-2H3,(H,23,24,26) VIGTXKQJJRKKOW-UHFFFAOYSA-N 50390892 CHEMBL2070985 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 2860 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390892&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 16827304 160869975 CHEMBL2070985 ZINC08869171 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952437 COc1ccc(cc1)-c1csc(NC(=O)C2CCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C21H21N3O4S2/c1-14-3-9-17(10-4-14)30(26,27)24-12-11-19(24)20(25)23-21-22-18(13-29-21)15-5-7-16(28-2)8-6-15/h3-10,13,19H,11-12H2,1-2H3,(H,22,23,25) VLXGLYHQIPMJHK-UHFFFAOYSA-N 50390893 CHEMBL2070986 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390893&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765379 160869976 CHEMBL2070986 ZINC84689224 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952438 COc1ccc(cc1)-c1csc(NC(=O)C2COCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C22H23N3O5S2/c1-15-3-9-18(10-4-15)32(27,28)25-11-12-30-13-20(25)21(26)24-22-23-19(14-31-22)16-5-7-17(29-2)8-6-16/h3-10,14,20H,11-13H2,1-2H3,(H,23,24,26) HCUSMCNNJXKDQT-UHFFFAOYSA-N 50390894 CHEMBL2070987 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 4380 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390894&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765372 160869977 CHEMBL2070987 ZINC84707246 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952439 COc1ccc(cc1)-c1csc(NC(=O)C2CSCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C22H23N3O4S3/c1-15-3-9-18(10-4-15)32(27,28)25-11-12-30-14-20(25)21(26)24-22-23-19(13-31-22)16-5-7-17(29-2)8-6-16/h3-10,13,20H,11-12,14H2,1-2H3,(H,23,24,26) LCDJDIULAZKOHC-UHFFFAOYSA-N 50390895 CHEMBL2070988 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 600 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390895&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765377 160869978 CHEMBL2070988 ZINC84707254 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952440 COc1ccc(cc1)-c1csc(NC(=O)C2CNCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C22H24N4O4S2/c1-15-3-9-18(10-4-15)32(28,29)26-12-11-23-13-20(26)21(27)25-22-24-19(14-31-22)16-5-7-17(30-2)8-6-16/h3-10,14,20,23H,11-13H2,1-2H3,(H,24,25,27) KOIHPOHJCCHBHO-UHFFFAOYSA-N 50390896 CHEMBL2070989 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390896&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765381 160869979 CHEMBL2070989 ZINC84707263 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952441 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCN(C2)S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C23H25N3O4S2/c1-16-5-11-20(12-6-16)32(28,29)26-13-3-4-18(14-26)22(27)25-23-24-21(15-31-23)17-7-9-19(30-2)10-8-17/h5-12,15,18H,3-4,13-14H2,1-2H3,(H,24,25,27)/t18-/m0/s1 BSPQWRDXTRJYCU-SFHVURJKSA-N 50390897 CHEMBL2070990 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390897&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 25923464 160869980 CHEMBL2070990 ZINC14020618 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952442 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCN(C2)S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C23H25N3O4S2/c1-16-5-11-20(12-6-16)32(28,29)26-13-3-4-18(14-26)22(27)25-23-24-21(15-31-23)17-7-9-19(30-2)10-8-17/h5-12,15,18H,3-4,13-14H2,1-2H3,(H,24,25,27)/t18-/m0/s1 BSPQWRDXTRJYCU-SFHVURJKSA-N 50390897 CHEMBL2070990 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390897&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 25923464 160869980 CHEMBL2070990 ZINC14020618 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952443 COc1ccc(cc1)-c1csc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C20H21N3O4S2/c1-14-3-9-17(10-4-14)29(25,26)21-12-11-19(24)23-20-22-18(13-28-20)15-5-7-16(27-2)8-6-15/h3-10,13,21H,11-12H2,1-2H3,(H,22,23,24) LXALJDUZPWJNTP-UHFFFAOYSA-N 50390898 CHEMBL2070992 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390898&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765373 160869981 CHEMBL2070992 ZINC84708652 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952444 COc1ccc(cc1)-c1csc(NC(=O)[C@H](NS(=O)(=O)c2ccc(C)cc2)C(C)(C)C)n1 InChI=1S/C23H27N3O4S2/c1-15-6-12-18(13-7-15)32(28,29)26-20(23(2,3)4)21(27)25-22-24-19(14-31-22)16-8-10-17(30-5)11-9-16/h6-14,20,26H,1-5H3,(H,24,25,27)/t20-/m0/s1 UANFYVVHKDEOGE-FQEVSTJZSA-N 50390899 CHEMBL2070993 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390899&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765374 160869982 CHEMBL2070993 ZINC84688412 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952445 COc1ccc(cc1)-c1csc(NC(=O)[C@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)n1 InChI=1S/C22H25N3O4S2/c1-14(2)20(25-31(27,28)18-11-5-15(3)6-12-18)21(26)24-22-23-19(13-30-22)16-7-9-17(29-4)10-8-16/h5-14,20,25H,1-4H3,(H,23,24,26)/t20-/m1/s1 NWDOZEFSUBNCRA-HXUWFJFHSA-N 50390900 CHEMBL2070994 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390900&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765375 160869983 CHEMBL2070994 ZINC84688413 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952446 COc1ccc(cc1)-c1csc(NC(=O)[C@@H](C)NS(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C20H21N3O4S2/c1-13-4-10-17(11-5-13)29(25,26)23-14(2)19(24)22-20-21-18(12-28-20)15-6-8-16(27-3)9-7-15/h4-12,14,23H,1-3H3,(H,21,22,24)/t14-/m1/s1 SLDWMTDVBWFVSC-CQSZACIVSA-N 50390901 CHEMBL2070995 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 12900 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390901&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765376 160869984 CHEMBL2070995 ZINC84672427 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952447 CC(C)c1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C25H29N3O3S2/c1-17(2)19-9-11-20(12-10-19)22-16-32-25(26-22)27-24(29)23-6-4-5-15-28(23)33(30,31)21-13-7-18(3)8-14-21/h7-14,16-17,23H,4-6,15H2,1-3H3,(H,26,27,29)/t23-/m1/s1 ADSSVNAXCSTXMN-HSZRJFAPSA-N 50390902 CHEMBL2070996 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390902&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488269 160869985 CHEMBL2070996 ZINC84688730 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952448 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccccc1 InChI=1S/C22H23N3O3S2/c1-16-10-12-18(13-11-16)30(27,28)25-14-6-5-9-20(25)21(26)24-22-23-19(15-29-22)17-7-3-2-4-8-17/h2-4,7-8,10-13,15,20H,5-6,9,14H2,1H3,(H,23,24,26)/t20-/m1/s1 FRSADCNODXSJOA-HXUWFJFHSA-N 50390903 CHEMBL2070997 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390903&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488271 160869986 CHEMBL2070997 ZINC84688731 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952449 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc(F)cc1 InChI=1S/C22H22FN3O3S2/c1-15-5-11-18(12-6-15)31(28,29)26-13-3-2-4-20(26)21(27)25-22-24-19(14-30-22)16-7-9-17(23)10-8-16/h5-12,14,20H,2-4,13H2,1H3,(H,24,25,27)/t20-/m1/s1 ZRUARDUGORUKHB-HXUWFJFHSA-N 50390904 CHEMBL2070998 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390904&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488272 160869987 CHEMBL2070998 ZINC84688732 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952450 Cc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C23H25N3O3S2/c1-16-6-10-18(11-7-16)20-15-30-23(24-20)25-22(27)21-5-3-4-14-26(21)31(28,29)19-12-8-17(2)9-13-19/h6-13,15,21H,3-5,14H2,1-2H3,(H,24,25,27)/t21-/m1/s1 XPAFYOHRMZYTQI-OAQYLSRUSA-N 50390905 CHEMBL2070999 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390905&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488273 160869988 CHEMBL2070999 ZINC84923903 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952451 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc(Cl)cc1 InChI=1S/C22H22ClN3O3S2/c1-15-5-11-18(12-6-15)31(28,29)26-13-3-2-4-20(26)21(27)25-22-24-19(14-30-22)16-7-9-17(23)10-8-16/h5-12,14,20H,2-4,13H2,1H3,(H,24,25,27)/t20-/m1/s1 UEILPNWTGNXVFQ-HXUWFJFHSA-N 50390906 CHEMBL2071001 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390906&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488283 160869989 CHEMBL2071001 ZINC84707389 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952452 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nccs1 InChI=1S/C16H19N3O3S2/c1-12-5-7-13(8-6-12)24(21,22)19-10-3-2-4-14(19)15(20)18-16-17-9-11-23-16/h5-9,11,14H,2-4,10H2,1H3,(H,17,18,20)/t14-/m1/s1 AVJXGTCULQJMMN-CQSZACIVSA-N 50390907 CHEMBL2071002 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390907&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 8762554 160869990 CHEMBL2071002 ZINC07654620 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952453 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc2ccccc2s1 InChI=1S/C20H21N3O3S2/c1-14-9-11-15(12-10-14)28(25,26)23-13-5-4-7-17(23)19(24)22-20-21-16-6-2-3-8-18(16)27-20/h2-3,6,8-12,17H,4-5,7,13H2,1H3,(H,21,22,24)/t17-/m1/s1 MOUXMVWWTHLIRR-QGZVFWFLSA-N 50390908 CHEMBL2071003 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390908&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 8881840 160869991 CHEMBL2071003 ZINC07766914 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952454 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc2occc2c1 InChI=1S/C24H23N3O4S2/c1-16-5-8-19(9-6-16)33(29,30)27-12-3-2-4-21(27)23(28)26-24-25-20(15-32-24)17-7-10-22-18(14-17)11-13-31-22/h5-11,13-15,21H,2-4,12H2,1H3,(H,25,26,28)/t21-/m1/s1 WXMLIBUKUNXGFC-OAQYLSRUSA-N 50390909 CHEMBL2071004 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1320 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390909&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947223 160869992 CHEMBL2071004 ZINC84708745 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952455 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc(OC(F)(F)F)cc1 InChI=1S/C23H22F3N3O4S2/c1-15-5-11-18(12-6-15)35(31,32)29-13-3-2-4-20(29)21(30)28-22-27-19(14-34-22)16-7-9-17(10-8-16)33-23(24,25)26/h5-12,14,20H,2-4,13H2,1H3,(H,27,28,30)/t20-/m1/s1 LVEKCAQUUIXWME-HXUWFJFHSA-N 50390910 CHEMBL2071005 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390910&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947233 160869993 CHEMBL2071005 ZINC84688467 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952456 COc1ccc(cc1)-c1cnc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)s1 InChI=1S/C23H25N3O4S2/c1-16-6-12-19(13-7-16)32(28,29)26-14-4-3-5-20(26)22(27)25-23-24-15-21(31-23)17-8-10-18(30-2)11-9-17/h6-13,15,20H,3-5,14H2,1-2H3,(H,24,25,27)/t20-/m1/s1 UKSXJENCMIVQMU-HXUWFJFHSA-N 50390911 CHEMBL2071006 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 27400 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390911&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947221 160869994 CHEMBL2071006 ZINC84688468 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952457 COc1ccc(cc1)-c1nnc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)s1 InChI=1S/C22H24N4O4S2/c1-15-6-12-18(13-7-15)32(28,29)26-14-4-3-5-19(26)20(27)23-22-25-24-21(31-22)16-8-10-17(30-2)11-9-16/h6-13,19H,3-5,14H2,1-2H3,(H,23,25,27)/t19-/m1/s1 QDVMTZJCMNKDGP-LJQANCHMSA-N 50390912 CHEMBL2071007 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390912&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947228 160869995 CHEMBL2071007 ZINC84672481 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952458 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1ncc(s1)-c1ccc2occc2c1 InChI=1S/C24H23N3O4S2/c1-16-5-8-19(9-6-16)33(29,30)27-12-3-2-4-20(27)23(28)26-24-25-15-22(32-24)18-7-10-21-17(14-18)11-13-31-21/h5-11,13-15,20H,2-4,12H2,1H3,(H,25,26,28)/t20-/m1/s1 XVQJFVHWDUDYPT-HXUWFJFHSA-N 50390913 CHEMBL2071008 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390913&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947229 160869996 CHEMBL2071008 ZINC84672482 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952459 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nnc(s1)-c1ccc2occc2c1 InChI=1S/C23H22N4O4S2/c1-15-5-8-18(9-6-15)33(29,30)27-12-3-2-4-19(27)21(28)24-23-26-25-22(32-23)17-7-10-20-16(14-17)11-13-31-20/h5-11,13-14,19H,2-4,12H2,1H3,(H,24,26,28)/t19-/m1/s1 PNUUEZVTQJSIHD-LJQANCHMSA-N 50390914 CHEMBL2071009 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390914&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947230 160869997 CHEMBL2071009 ZINC84672483 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952460 COc1ccc(cc1)-c1nnc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(Cl)cc2)s1 InChI=1S/C21H21ClN4O4S2/c1-30-16-9-5-14(6-10-16)20-24-25-21(31-20)23-19(27)18-4-2-3-13-26(18)32(28,29)17-11-7-15(22)8-12-17/h5-12,18H,2-4,13H2,1H3,(H,23,25,27)/t18-/m1/s1 FIAYZHOGRGVADF-GOSISDBHSA-N 50390915 CHEMBL2071010 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390915&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 56947232 160869998 CHEMBL2071010 ZINC84672484 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952464 COc1ccc(cc1)-c1csc(NC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)n1 InChI=1S/C22H23N3O4S2/c1-29-17-12-10-16(11-13-17)19-15-30-22(23-19)24-21(26)20-9-5-6-14-25(20)31(27,28)18-7-3-2-4-8-18/h2-4,7-8,10-13,15,20H,5-6,9,14H2,1H3,(H,23,24,26) UUTYPVHYRISWDI-UHFFFAOYSA-N 50390917 CHEMBL1352968 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1690 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390917&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 4880560 160870000 CHEMBL1352968 ZINC03347467 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952465 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2)n1 InChI=1S/C22H23N3O4S2/c1-29-17-12-10-16(11-13-17)19-15-30-22(23-19)24-21(26)20-9-5-6-14-25(20)31(27,28)18-7-3-2-4-8-18/h2-4,7-8,10-13,15,20H,5-6,9,14H2,1H3,(H,23,24,26)/t20-/m1/s1 UUTYPVHYRISWDI-HXUWFJFHSA-N 50390918 CHEMBL2070830 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1470 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390918&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 2464255 160870001 CHEMBL2070830 ZINC03347465 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952466 COc1ccc(cc1)-c1csc(NC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccccc2)n1 InChI=1S/C22H23N3O4S2/c1-29-17-12-10-16(11-13-17)19-15-30-22(23-19)24-21(26)20-9-5-6-14-25(20)31(27,28)18-7-3-2-4-8-18/h2-4,7-8,10-13,15,20H,5-6,9,14H2,1H3,(H,23,24,26)/t20-/m0/s1 UUTYPVHYRISWDI-FQEVSTJZSA-N 50390919 CHEMBL2070831 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390919&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 2464257 160870002 CHEMBL2070831 ZINC03347467 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952467 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2C)n1 InChI=1S/C23H25N3O4S2/c1-16-7-3-4-9-21(16)32(28,29)26-14-6-5-8-20(26)22(27)25-23-24-19(15-31-23)17-10-12-18(30-2)13-11-17/h3-4,7,9-13,15,20H,5-6,8,14H2,1-2H3,(H,24,25,27)/t20-/m1/s1 PHZNXLUFAOGZJS-HXUWFJFHSA-N 50390920 CHEMBL2070832 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1380 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390920&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347926 160870003 CHEMBL2070832 ZINC84711246 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952468 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(C)c2)n1 InChI=1S/C23H25N3O4S2/c1-16-6-5-7-19(14-16)32(28,29)26-13-4-3-8-21(26)22(27)25-23-24-20(15-31-23)17-9-11-18(30-2)12-10-17/h5-7,9-12,14-15,21H,3-4,8,13H2,1-2H3,(H,24,25,27)/t21-/m1/s1 GHFNEDCFRFXUPC-OAQYLSRUSA-N 50390921 CHEMBL2070952 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 890 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390921&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488275 160870004 CHEMBL2070952 ZINC84712888 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952469 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1 InChI=1S/C23H25N3O4S2/c1-16-6-12-19(13-7-16)32(28,29)26-14-4-3-5-21(26)22(27)25-23-24-20(15-31-23)17-8-10-18(30-2)11-9-17/h6-13,15,21H,3-5,14H2,1-2H3,(H,24,25,27)/t21-/m1/s1 OXQNLLVUVDAEHC-OAQYLSRUSA-N 50390916 CHEMBL2070953 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 260 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390916&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search I0S 7TCI,7XNN,7XNL,7XNK 53347902 160869999 CHEMBL2070953 ZINC84712890 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952470 CCCc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc(OC)cc1 InChI=1S/C25H29N3O4S2/c1-3-6-18-8-14-21(15-9-18)34(30,31)28-16-5-4-7-23(28)24(29)27-25-26-22(17-33-25)19-10-12-20(32-2)13-11-19/h8-15,17,23H,3-7,16H2,1-2H3,(H,26,27,29)/t23-/m1/s1 XJYFAQRRMUXSRE-HSZRJFAPSA-N 50390922 CHEMBL2070954 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 700 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390922&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765446 160870005 CHEMBL2070954 ZINC84713725 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952471 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(cc2)C(C)C)n1 InChI=1S/C25H29N3O4S2/c1-17(2)18-9-13-21(14-10-18)34(30,31)28-15-5-4-6-23(28)24(29)27-25-26-22(16-33-25)19-7-11-20(32-3)12-8-19/h7-14,16-17,23H,4-6,15H2,1-3H3,(H,26,27,29)/t23-/m1/s1 ZRVBBUATVKPQGK-HSZRJFAPSA-N 50390923 CHEMBL2070955 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 2590 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390923&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765447 160870006 CHEMBL2070955 ZINC84713729 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952472 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 InChI=1S/C26H31N3O4S2/c1-26(2,3)19-10-14-21(15-11-19)35(31,32)29-16-6-5-7-23(29)24(30)28-25-27-22(17-34-25)18-8-12-20(33-4)13-9-18/h8-15,17,23H,5-7,16H2,1-4H3,(H,27,28,30)/t23-/m1/s1 OQLFDDLSQGEIBA-HSZRJFAPSA-N 50390924 CHEMBL2070956 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390924&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 54765445 160870007 CHEMBL2070956 ZINC84712932 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952473 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccccc2C(F)(F)F)n1 InChI=1S/C23H22F3N3O4S2/c1-33-16-11-9-15(10-12-16)18-14-34-22(27-18)28-21(30)19-7-4-5-13-29(19)35(31,32)20-8-3-2-6-17(20)23(24,25)26/h2-3,6,8-12,14,19H,4-5,7,13H2,1H3,(H,27,28,30)/t19-/m1/s1 UOABDKNXSCKGLJ-LJQANCHMSA-N 50390925 CHEMBL2070957 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 4740 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390925&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347904 160870008 CHEMBL2070957 ZINC84690216 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952474 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2C(=O)c2cccc(F)c2)n1 InChI=1S/C23H22FN3O3S/c1-30-18-10-8-15(9-11-18)19-14-31-23(25-19)26-21(28)20-7-2-3-12-27(20)22(29)16-5-4-6-17(24)13-16/h4-6,8-11,13-14,20H,2-3,7,12H2,1H3,(H,25,26,28)/t20-/m1/s1 RHADGVIDFAHDIJ-HXUWFJFHSA-N 50390926 CHEMBL2070981 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 6130 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390926&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347920 160870009 CHEMBL2070981 ZINC84689736 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952475 Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc(cc1)[N+]([O-])=O InChI=1S/C22H22N4O5S2/c1-15-5-11-18(12-6-15)33(30,31)25-13-3-2-4-20(25)21(27)24-22-23-19(14-32-22)16-7-9-17(10-8-16)26(28)29/h5-12,14,20H,2-4,13H2,1H3,(H,23,24,27)/t20-/m1/s1 KSJPANOFHAQMDD-HXUWFJFHSA-N 50390927 CHEMBL2071000 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390927&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53488282 160870010 CHEMBL2071000 ZINC84707385 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50952476 COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2cccc(c2)C(F)(F)F)n1 InChI=1S/C23H22F3N3O4S2/c1-33-17-10-8-15(9-11-17)19-14-34-22(27-19)28-21(30)20-7-2-3-12-29(20)35(31,32)18-6-4-5-16(13-18)23(24,25)26/h4-6,8-11,13-14,20H,2-3,7,12H2,1H3,(H,27,28,30)/t20-/m1/s1 BWBXOBFPELPHEA-HXUWFJFHSA-N 50390928 CHEMBL2070958 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 1000 ChEMBL 10.1016/j.bmcl.2012.07.060 10.7270/Q25T3MKN 22910039 Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390928&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 53347894 160870011 CHEMBL2070958 ZINC84690217 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50964497 CC[C@H](C(=O)Nc1ccccc1N1CCCC1)c1ccccc1 InChI=1S/C20H24N2O/c1-2-17(16-10-4-3-5-11-16)20(23)21-18-12-6-7-13-19(18)22-14-8-9-15-22/h3-7,10-13,17H,2,8-9,14-15H2,1H3,(H,21,23)/t17-/m0/s1 FROGGFONBYACJB-KRWDZBQOSA-N 50395464 CHEMBL2164048 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 2920 ChEMBL 10.1021/jm300700v 10.7270/Q2KD2017 22793372 Cheung, YY; Yu, H; Xu, K; Zou, B; Wu, M; McManus, OB; Li, M; Lindsley, CW; Hopkins, CR Vanderbilt University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395464&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 26873419 163344488 CHEMBL2164048 ZINC15941024 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51045154 NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24) SCTZUZTYRMOMKT-UHFFFAOYSA-N 50371391 SENICAPOC Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >1000 ChEMBL 10.1021/jm3011433 10.7270/Q23B61GZ 23121096 Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371391&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 216327 160850492 ZINC03816408 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50799187 Fc1ccc(Nc2n[nH]c3cc(OC(F)(F)F)cnc23)cc1F InChI=1S/C13H7F5N4O/c14-8-2-1-6(3-9(8)15)20-12-11-10(21-22-12)4-7(5-19-11)23-13(16,17)18/h1-5H,(H2,20,21,22) QGIXOJCLJSPCPO-UHFFFAOYSA-N 50254387 CHEMBL4062193 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 2640 ChEMBL 10.1021/acsmedchemlett.7b00140 10.7270/Q2C24ZWG 28626530 Pryde, DC; Marron, BE; West, CW; Reister, S; Amato, G; Yoger, K; Antonio, B; Padilla, K; Cox, PJ; Turner, J; Warmus, JS; Swain, NA; Omoto, K; Mahoney, JH; Gerlach, AC Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254387&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 137637559 402359991 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50799188 FC(F)(F)Oc1ccc2c(n[nH]c2c1)-c1ccc(cc1)C#N InChI=1S/C15H8F3N3O/c16-15(17,18)22-11-5-6-12-13(7-11)20-21-14(12)10-3-1-9(8-19)2-4-10/h1-7H,(H,20,21) RIUFXWHYQAUEAO-UHFFFAOYSA-N 50254388 CHEMBL4101680 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >3000 ChEMBL 10.1021/acsmedchemlett.7b00140 10.7270/Q2C24ZWG 28626530 Pryde, DC; Marron, BE; West, CW; Reister, S; Amato, G; Yoger, K; Antonio, B; Padilla, K; Cox, PJ; Turner, J; Warmus, JS; Swain, NA; Omoto, K; Mahoney, JH; Gerlach, AC Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254388&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 137661020 402359992 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 50799262 FC(F)(F)c1ccc2c(Nc3ccc(Cl)nc3)n[nH]c2c1 InChI=1S/C13H8ClF3N4/c14-11-4-2-8(6-18-11)19-12-9-3-1-7(13(15,16)17)5-10(9)20-21-12/h1-6H,(H2,19,20,21) GNYBHKXPQGYGCV-UHFFFAOYSA-N 50254401 CHEMBL4093377 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 2600 ChEMBL 10.1021/acsmedchemlett.7b00140 10.7270/Q2C24ZWG 28626530 Pryde, DC; Marron, BE; West, CW; Reister, S; Amato, G; Yoger, K; Antonio, B; Padilla, K; Cox, PJ; Turner, J; Warmus, JS; Swain, NA; Omoto, K; Mahoney, JH; Gerlach, AC Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254401&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 9883254 402359993 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51241335 C[C@H]([C@H](N)c1nc2ccc(cc2[nH]1)C(C)(C)C)C(N)=O InChI=1S/C15H22N4O/c1-8(13(17)20)12(16)14-18-10-6-5-9(15(2,3)4)7-11(10)19-14/h5-8,12H,16H2,1-4H3,(H2,17,20)(H,18,19)/t8-,12+/m1/s1 APWZIFIAVVFPNT-PELKAZGASA-N 50507839 PF-6305591::Pf-06305591 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >30000 ChEMBL 10.1016/j.bmc.2018.12.002 10.7270/Q2ZK5KZN 30538065 Brown, AD; Bagal, SK; Blackwell, P; Blakemore, DC; Brown, B; Bungay, PJ; Corless, M; Crawforth, J; Fengas, D; Fenwick, DR; Gray, V; Kemp, M; Klute, W; Malet Sanz, L; Miller, D; Murata, Y; Payne, CE; Skerratt, S; Stevens, EB; Warmus, JS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50507839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50507839&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 71666749 440716424 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51285523 Cc1cc([nH]n1)-c1ccc(cc1)C(=O)[C@@H]1CCCC[C@H]1C(=O)Nc1cnn(C)c1C(=O)NOC(C)(C)C InChI=1S/C27H34N6O4/c1-16-14-21(31-30-16)17-10-12-18(13-11-17)24(34)19-8-6-7-9-20(19)25(35)29-22-15-28-33(5)23(22)26(36)32-37-27(2,3)4/h10-15,19-20H,6-9H2,1-5H3,(H,29,35)(H,30,31)(H,32,36)/t19-,20-/m1/s1 BMQWIMXUMVEYAP-WOJBJXKFSA-N 50524103 CHEMBL4563459 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >33000 ChEMBL 10.1021/acs.jmedchem.8b02004 10.7270/Q25T3PXZ 30869888 Pettersen, D; Broddefalk, J; Emtenäs, H; Hayes, MA; Lemurell, M; Swanson, M; Ulander, J; Whatling, C; Amilon, C; Ericsson, H; Westin Eriksson, A; Granberg, K; Plowright, AT; Shamovsky, I; Dellsèn, A; Sundqvist, M; Någård, M; Lindstedt, EL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50524103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50524103&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 155559364 440732685 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51285524 Cc1cc(n[nH]1)-c1ccc(cc1)C(=O)[C@@H]1CCCC[C@H]1C(=O)Nc1cnn2CCNC(=O)c12 InChI=1S/C24H26N6O3/c1-14-12-19(29-28-14)15-6-8-16(9-7-15)22(31)17-4-2-3-5-18(17)23(32)27-20-13-26-30-11-10-25-24(33)21(20)30/h6-9,12-13,17-18H,2-5,10-11H2,1H3,(H,25,33)(H,27,32)(H,28,29)/t17-,18-/m1/s1 ROTWSDMXHVGAHZ-QZTJIDSGSA-N 50524102 CHEMBL4542281 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >33000 ChEMBL 10.1021/acs.jmedchem.8b02004 10.7270/Q25T3PXZ 30869888 Pettersen, D; Broddefalk, J; Emtenäs, H; Hayes, MA; Lemurell, M; Swanson, M; Ulander, J; Whatling, C; Amilon, C; Ericsson, H; Westin Eriksson, A; Granberg, K; Plowright, AT; Shamovsky, I; Dellsèn, A; Sundqvist, M; Någård, M; Lindstedt, EL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50524102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50524102&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 122678117 440732684 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51285544 Cc1cc(n[nH]1)-c1ccc(cc1)C(=O)[C@@H]1CCCC[C@H]1C(=O)Nc1cnn(C)c1S(N)(=O)=O InChI=1S/C22H26N6O4S/c1-13-11-18(27-26-13)14-7-9-15(10-8-14)20(29)16-5-3-4-6-17(16)21(30)25-19-12-24-28(2)22(19)33(23,31)32/h7-12,16-17H,3-6H2,1-2H3,(H,25,30)(H,26,27)(H2,23,31,32)/t16-,17-/m1/s1 IVYACETTWFJKQK-IAGOWNOFSA-N 50524101 CHEMBL4474619 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >33000 ChEMBL 10.1021/acs.jmedchem.8b02004 10.7270/Q25T3PXZ 30869888 Pettersen, D; Broddefalk, J; Emtenäs, H; Hayes, MA; Lemurell, M; Swanson, M; Ulander, J; Whatling, C; Amilon, C; Ericsson, H; Westin Eriksson, A; Granberg, K; Plowright, AT; Shamovsky, I; Dellsèn, A; Sundqvist, M; Någård, M; Lindstedt, EL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50524101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50524101&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 122678192 440732683 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51379305 C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1nc(no1)-c1ccnc(c1)C(F)(F)F InChI=1S/C16H12F6N6O2/c1-7(24-13(29)9-6-11(16(20,21)22)26-28(9)2)14-25-12(27-30-14)8-3-4-23-10(5-8)15(17,18)19/h3-7H,1-2H3,(H,24,29)/t7-/m0/s1 SFSLHKNGLMRBTO-ZETCQYMHSA-N 50557680 CHEMBL4741793 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 18500 ChEMBL 10.1021/acsmedchemlett.0c00675 10.7270/Q2QF8XJ0 33859800 Griffin, AM; Kahlig, KM; Hatch, RJ; Hughes, ZA; Chapman, ML; Antonio, B; Marron, BE; Wittmann, M; Martinez-Botella, G Praxis Precision Medicines http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50557680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50557680&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 155272065 461828072 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51373195 FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1 InChI=1S/C16H16F3N7O/c17-16(18,19)12-8-25-14(26-15-9-22-10(4-20)5-24-15)3-13(12)23-7-11-6-21-1-2-27-11/h3,5,8-9,11,21H,1-2,6-7H2,(H2,23,24,25,26)/t11-/m1/s1 YBYYWUUUGCNAHQ-LLVKDONJSA-N 328993 5-[[4-[[(2R)-morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile::US9663503, Compound 1 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.5b01938 10.7270/Q2MG7T5V 27167172 Osborne, JD; Matthews, TP; McHardy, T; Proisy, N; Cheung, KM; Lainchbury, M; Brown, N; Walton, MI; Eve, PD; Boxall, KJ; Hayes, A; Henley, AT; Valenti, MR; De Haven Brandon, AK; Box, G; Jamin, Y; Robinson, SP; Westwood, IM; van Montfort, RL; Leonard, PM; Lamers, MB; Reader, JC; Aherne, GW; Raynaud, FI; Eccles, SA; Garrett, MD; Collins, I Sareum Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=328993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=328993&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 72165232 384573914 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51526113 CSc1c(C#N)c(=O)c2ccc(F)cc2n1-c1c(Cl)cccc1Cl InChI=1S/C17H9Cl2FN2OS/c1-24-17-11(8-21)16(23)10-6-5-9(20)7-14(10)22(17)15-12(18)3-2-4-13(15)19/h2-7H,1H3 AWQZXHDLUBADMM-UHFFFAOYSA-N 50613992 CHEMBL5282689 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens 33000 ChEMBL 10.7270/Q2MG7TRG 36924945 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613992&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 171353859 494503740 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51526114 Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N InChI=1S/C16H8Cl2FN3O/c1-8-2-14(23)15-12(19)6-21-7-13(15)22(8)16-10(17)3-9(5-20)4-11(16)18/h2-4,6-7H,1H3 MLKRCEWWRVAFRU-UHFFFAOYSA-N 50613993 CHEMBL5286246 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >50000 ChEMBL 10.7270/Q2MG7TRG 36924945 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613993&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 134453147 494503741 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51526115 OC[C@@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl InChI=1S/C18H15Cl3N2O5/c19-11-2-1-3-12(20)16(11)23-9(6-24)4-14(27)15-17(23)13(21)5-22-18(15)28-8-10(26)7-25/h1-5,10,24-26H,6-8H2/t10-/m1/s1 DDDSGZFENQKDDY-SNVBAGLBSA-N 585681 (R)-8-chloro-1-(2,6- dichlorophenyl)-5-(2,3- dihydroxypropoxy)-2- (hydroxymethyl)-1,6-naphthyridin- 4(1H)-one::US11530213, Example 2 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >50000 ChEMBL 10.7270/Q2MG7TRG 36924945 Peukert, S; Gulgeze Efthymiou, HB; Mo, R; Peng, Y; Ma, F; Barbe, G; Bebernitz, G; Fridrich, C; Buono, C; Williams, ET; Daniels, T; Li, L; Zhang, X; Adachi, Y; Abe, M; Taggart, AKP Novartis Institutes For Biomedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=585681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=585681&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 134453154 475955309 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9 51526116 OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl InChI=1S/C18H15Cl3N2O5/c19-11-2-1-3-12(20)16(11)23-9(6-24)4-14(27)15-17(23)13(21)5-22-18(15)28-8-10(26)7-25/h1-5,10,24-26H,6-8H2/t10-/m0/s1 DDDSGZFENQKDDY-JTQLQIEISA-N 585680 US11530213, Example 1 Potassium voltage-gated channel subfamily KQT member 1 Homo sapiens >50000 ChEMBL 10.7270/Q2MG7TRG 36924945 Peukert, S; Gulgeze Efthymiou, HB; Mo, R; Peng, Y; Ma, F; Barbe, G; Bebernitz, G; Fridrich, C; Buono, C; Williams, ET; Daniels, T; Li, L; Zhang, X; Adachi, Y; Abe, M; Taggart, AKP Novartis Institutes For Biomedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=585680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002487&target=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=585680&enzyme=Potassium+voltage-gated+channel+subfamily+KQT+member+1&column=ki&startPg=0&Increment=50&submit=Search 134453155 475955308 1 MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS 3BJ4,6MIE,7XNI,7XNK,7XNL,7XNN Potassium voltage-gated channel subfamily KQT member 1 KCNQ1_HUMAN P51787 O00347 O60607 O94787 Q14D14 Q7Z6G9 Q92960 Q9UMN8 Q9UMN9