BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50003258 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCC1CNCCN1c1ccccc1 InChI=1S/C19H24N4O3S/c1-27(25,26)22-16-9-7-15(8-10-16)19(24)21-14-18-13-20-11-12-23(18)17-5-3-2-4-6-17/h2-10,18,20,22H,11-14H2,1H3,(H,21,24) YZCHWNNPTWRQKX-UHFFFAOYSA-N 50001902 4-Methanesulfonylamino-N-(1-phenyl-piperazin-2-ylmethyl)-benzamide::CHEMBL162095 Beta-2 adrenergic receptor Canis familiaris 31000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001902&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998847 103916269 CHEMBL162095 ZINC49925387 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003260 Cc1ccc(cc1)N1CCNCC1 InChI=1S/C11H16N2/c1-10-2-4-11(5-3-10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 ONEYFZXGNFNRJH-UHFFFAOYSA-N 50001911 1-p-Tolyl-piperazine::CHEMBL165462 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001911&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 83113 103916278 CHEMBL165462 ZINC04707825 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003261 CS(=O)(=O)Nc1ccc(CNCC2CN(CCN2)c2ccccc2)cc1 InChI=1S/C19H26N4O2S/c1-26(24,25)22-17-9-7-16(8-10-17)13-20-14-18-15-23(12-11-21-18)19-5-3-2-4-6-19/h2-10,18,20-22H,11-15H2,1H3 UZPZDTUIIXEVNN-UHFFFAOYSA-N 50001909 CHEMBL163153::N-(4-{[(4-Phenyl-piperazin-2-ylmethyl)-amino]-methyl}-phenyl)-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 4600 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001909&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998846 103916276 CHEMBL163153 ZINC22442866 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003263 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCC1CN(CCN1)c1cccc(Cl)c1 InChI=1S/C19H23ClN4O3S/c1-28(26,27)23-16-7-5-14(6-8-16)19(25)22-12-17-13-24(10-9-21-17)18-4-2-3-15(20)11-18/h2-8,11,17,21,23H,9-10,12-13H2,1H3,(H,22,25) YQIGZMOUSYESEY-UHFFFAOYSA-N 50001914 CHEMBL350432::N-[4-(3-Chloro-phenyl)-piperazin-2-ylmethyl]-4-methanesulfonylamino-benzamide Beta-2 adrenergic receptor Canis familiaris 3800 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001914&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998858 103916281 CHEMBL350432 ZINC49759799 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003264 COc1ccc(cc1)N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-4-2-10(3-5-11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 MRDGZSKYFPGAKP-UHFFFAOYSA-N 50001913 1-(4-Methoxy-phenyl)-piperazine::4-METHOXYPHENYLPIPERAZINE::CHEMBL59517 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001913&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 269722 103916280 CHEMBL59517 ZINC00157604 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003266 CS(=O)(=O)Nc1ccc(NC(=O)C2CN(CCN2)c2ccccc2)cc1 InChI=1S/C18H22N4O3S/c1-26(24,25)21-15-9-7-14(8-10-15)20-18(23)17-13-22(12-11-19-17)16-5-3-2-4-6-16/h2-10,17,19,21H,11-13H2,1H3,(H,20,23) PGJYMBMOPPPBME-UHFFFAOYSA-N 50001916 4-Phenyl-piperazine-2-carboxylic acid (4-methanesulfonylamino-phenyl)-amide::CHEMBL163363 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001916&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 15123377 103916283 CHEMBL163363 ZINC49925451 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003272 COc1cccc(c1)N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-4-2-3-10(9-11)13-7-5-12-6-8-13/h2-4,9,12H,5-8H2,1H3 PZIBVWUXWNYTNL-UHFFFAOYSA-N 50001917 1-(3-Methoxy-phenyl)-piperazine::CHEMBL59597 Beta-2 adrenergic receptor Canis familiaris 29000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001917&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 81430 103916284 CHEMBL59597 ZINC00066034 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003277 COc1cccc(c1)N1CCNC(CNC(=O)c2ccc(NS(C)(=O)=O)cc2)C1 InChI=1S/C20H26N4O4S/c1-28-19-5-3-4-18(12-19)24-11-10-21-17(14-24)13-22-20(25)15-6-8-16(9-7-15)23-29(2,26)27/h3-9,12,17,21,23H,10-11,13-14H2,1-2H3,(H,22,25) HTUZPHQYHWKKIZ-UHFFFAOYSA-N 50001905 4-Methanesulfonylamino-N-[4-(3-methoxy-phenyl)-piperazin-2-ylmethyl]-benzamide::CHEMBL163587 Beta-2 adrenergic receptor Canis familiaris 3500 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001905&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998849 103916272 CHEMBL163587 ZINC49925454 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003279 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 Beta-2 adrenergic receptor Canis familiaris 34000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003280 Cc1ccccc1N1CCNCC1 InChI=1S/C11H16N2/c1-10-4-2-3-5-11(10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 WICKLEOONJPMEQ-UHFFFAOYSA-N 50001903 1-o-Tolyl-piperazine::CHEMBL9746 Beta-2 adrenergic receptor Canis familiaris 29000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001903&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 91965 103916270 CHEMBL9746 ZINC00066076 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003281 O=C(NCC1CN(CCN1)c1ccccc1)c1ccccc1 InChI=1S/C18H21N3O/c22-18(15-7-3-1-4-8-15)20-13-16-14-21(12-11-19-16)17-9-5-2-6-10-17/h1-10,16,19H,11-14H2,(H,20,22) ZIDZMPRPKCDKSS-UHFFFAOYSA-N 50001896 CHEMBL165901::N-(4-Phenyl-piperazin-2-ylmethyl)-benzamide Beta-2 adrenergic receptor Canis familiaris 6200 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001896&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 15123375 103916263 CHEMBL165901 ZINC11422327 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003282 Clc1ccc(cc1)N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 UNEIHNMKASENIG-UHFFFAOYSA-N 50001897 1-(4-Chloro-phenyl)-piperazine::CHEMBL114478::pCPP Beta-2 adrenergic receptor Canis familiaris 70000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001897&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 97478 103916264 CHEMBL114478 ZINC00066019 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003286 CS(=O)(=O)Nc1ccc(cc1)C(=O)NCC1CN(CCN1)c1ccccc1 InChI=1S/C19H24N4O3S/c1-27(25,26)22-16-9-7-15(8-10-16)19(24)21-13-17-14-23(12-11-20-17)18-5-3-2-4-6-18/h2-10,17,20,22H,11-14H2,1H3,(H,21,24) GIUNEOHGDSNUIQ-UHFFFAOYSA-N 50001912 4-Methanesulfonylamino-N-(4-phenyl-piperazin-2-ylmethyl)-benzamide::CHEMBL162513 Beta-2 adrenergic receptor Canis familiaris 3400 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001912&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 131847 103916279 CHEMBL162513 ZINC49925428 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003287 CC(=O)c1ccc(cc1)N1CCNCC1 InChI=1S/C12H16N2O/c1-10(15)11-2-4-12(5-3-11)14-8-6-13-7-9-14/h2-5,13H,6-9H2,1H3 KPXVKKBJROCIJB-UHFFFAOYSA-N 50001899 1-(4-Piperazin-1-yl-phenyl)-ethanone::CHEMBL166330 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001899&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 97269 103916266 CHEMBL166330 ZINC00029076 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003288 CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 ZBMZVLHSJCTVON-UHFFFAOYSA-N 25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245 Beta-2 adrenergic receptor Canis familiaris 5000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25762&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5253 56413050 63622 CHEMBL471 DB00489 7297 C07309 ZINC49552142 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003289 [O-][N+](=O)c1ccc(cc1)N1CCNCC1 InChI=1S/C10H13N3O2/c14-13(15)10-3-1-9(2-4-10)12-7-5-11-6-8-12/h1-4,11H,5-8H2 VWOJSRICSKDKAW-UHFFFAOYSA-N 50001908 1-(4-Nitro-phenyl)-piperazine::CHEMBL165012 Beta-2 adrenergic receptor Canis familiaris 56000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001908&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 80447 103916275 CHEMBL165012 ZINC03860568 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003290 CN(c1ccc(cc1)C(=O)NCC1CN(CCN1)c1ccccc1)S(C)(=O)=O InChI=1S/C20H26N4O3S/c1-23(28(2,26)27)18-10-8-16(9-11-18)20(25)22-14-17-15-24(13-12-21-17)19-6-4-3-5-7-19/h3-11,17,21H,12-15H2,1-2H3,(H,22,25) KYAHCCSGINNXKL-UHFFFAOYSA-N 50001910 4-(Methanesulfonyl-methyl-amino)-N-(4-phenyl-piperazin-2-ylmethyl)-benzamide::CHEMBL162200 Beta-2 adrenergic receptor Canis familiaris 4300 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001910&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998855 103916277 CHEMBL162200 ZINC06013398 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003293 COc1ccccc1N1CCNC(CNC(=O)c2ccc(NS(C)(=O)=O)cc2)C1 InChI=1S/C20H26N4O4S/c1-28-19-6-4-3-5-18(19)24-12-11-21-17(14-24)13-22-20(25)15-7-9-16(10-8-15)23-29(2,26)27/h3-10,17,21,23H,11-14H2,1-2H3,(H,22,25) KSSFMKSIGXBNOC-UHFFFAOYSA-N 50001906 4-Methanesulfonylamino-N-[4-(2-methoxy-phenyl)-piperazin-2-ylmethyl]-benzamide::CHEMBL349978 Beta-2 adrenergic receptor Canis familiaris 630 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001906&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998850 103916273 CHEMBL349978 ZINC49756718 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003294 CS(=O)(=O)Nc1ccc(NCC2CN(CCN2)c2ccccc2)cc1 InChI=1S/C18H24N4O2S/c1-25(23,24)21-16-9-7-15(8-10-16)20-13-17-14-22(12-11-19-17)18-5-3-2-4-6-18/h2-10,17,19-21H,11-14H2,1H3 LJZGGUYZECFQST-UHFFFAOYSA-N 50001900 CHEMBL162182::N-{4-[(4-Phenyl-piperazin-2-ylmethyl)-amino]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 1000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001900&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998852 103916267 CHEMBL162182 ZINC49925430 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003297 CS(=O)(=O)Nc1ccc(NCC2CNCCN2c2ccccc2)cc1 InChI=1S/C18H24N4O2S/c1-25(23,24)21-16-9-7-15(8-10-16)20-14-18-13-19-11-12-22(18)17-5-3-2-4-6-17/h2-10,18-21H,11-14H2,1H3 AFYXROQLTFFXOK-UHFFFAOYSA-N 50001894 CHEMBL351183::N-{4-[(1-Phenyl-piperazin-2-ylmethyl)-amino]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 42000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001894&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998853 103916261 CHEMBL351183 ZINC06013392 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003299 C1CN(CCN1)c1ccccc1 InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 YZTJYBJCZXZGCT-UHFFFAOYSA-N 50001898 1-Phenyl-piperazine::CHEMBL9434::PHENYLPIPERAZINE Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001898&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search VU9 7FMY 7096 103916265 CHEMBL9434 ZINC00120271 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003300 Clc1ccccc1N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 PWZDJIUQHUGFRJ-UHFFFAOYSA-N 50001901 1-(2-Chloro-phenyl)-piperazine::CHEMBL9841 Beta-2 adrenergic receptor Canis familiaris 16000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001901&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 415628 103916268 CHEMBL9841 ZINC00015872 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003301 Cc1cccc(c1)N1CCNCC1 InChI=1S/C11H16N2/c1-10-3-2-4-11(9-10)13-7-5-12-6-8-13/h2-4,9,12H,5-8H2,1H3 JIWHIRLNKIUYSM-UHFFFAOYSA-N 50001904 1-m-Tolyl-piperazine::CHEMBL165175 Beta-2 adrenergic receptor Canis familiaris 40000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001904&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 83111 103916271 CHEMBL165175 ZINC00066066 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003303 CS(=O)(=O)Nc1ccc(OCC2CN(CCN2)c2ccccc2)cc1 InChI=1S/C18H23N3O3S/c1-25(22,23)20-15-7-9-18(10-8-15)24-14-16-13-21(12-11-19-16)17-5-3-2-4-6-17/h2-10,16,19-20H,11-14H2,1H3 AOWVAMXBGYCCHV-UHFFFAOYSA-N 50001895 CHEMBL350581::N-[4-(4-Phenyl-piperazin-2-ylmethoxy)-phenyl]-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 4500 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001895&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998851 103916262 CHEMBL350581 ZINC49759908 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003304 O=C(NCC1CN(CCN1)c1ccccc1)c1ccc(cc1)-n1ccnc1 InChI=1S/C21H23N5O/c27-21(17-6-8-20(9-7-17)26-12-10-22-16-26)24-14-18-15-25(13-11-23-18)19-4-2-1-3-5-19/h1-10,12,16,18,23H,11,13-15H2,(H,24,27) LRNFWXDBPHKDSW-UHFFFAOYSA-N 50001907 4-Imidazol-1-yl-N-(4-phenyl-piperazin-2-ylmethyl)-benzamide::CHEMBL350847 Beta-2 adrenergic receptor Canis familiaris 4300 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001907&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14998848 103916274 CHEMBL350847 ZINC11422332 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003305 Clc1cccc(c1)N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 VHFVKMTVMIZMIK-UHFFFAOYSA-N 50001915 1-(3-chlorophenyl)piperazine::CHEMBL478::m-Chlorophenylpiperazine::mCPP Beta-2 adrenergic receptor Canis familiaris 18000 ChEMBL 10.1021/jm00082a016 10.7270/Q2319TT0 1347318 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001915&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 1355 103916282 10588 CHEMBL478 142 C11738 ZINC00004285 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50003580 CC(C)NCC(O)c1ccc(O)c(O)c1 InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 JWZZKOKVBUJMES-UHFFFAOYSA-N 25392 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride::4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol::4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2::CHEMBL434::ISOPROTERONOL::Isoprenaline::Isoproterenol::Isoproterenol (-)::Isoproterenol,(+)::Isoproterenol-l::Norisodrine::Novodrin Beta-2 adrenergic receptor Canis familiaris 1000 ChEMBL 10.1021/jm00094a025 10.7270/Q2PR7TWN 1354264 Bloom, JD; Dutia, MD; Johnson, BD; Wissner, A; Burns, MG; Largis, EE; Dolan, JA; Claus, TH American Cyanamid Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25392&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5FW 7S0F,7S0G,5YTU,7JJO,4A7T,2Y03,7XJH,7DHR,6H7J 3779 56374531 64317 CHEMBL434 DB01064 536 C02012 ZINC00056653 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032595 Cc1cccc(OCC(O)CN2CCN(CC2)c2ccc(NS(C)(=O)=O)cc2)c1 InChI=1S/C21H29N3O4S/c1-17-4-3-5-21(14-17)28-16-20(25)15-23-10-12-24(13-11-23)19-8-6-18(7-9-19)22-29(2,26)27/h3-9,14,20,22,25H,10-13,15-16H2,1-2H3 QNDDXCZGZXSBCC-UHFFFAOYSA-N 50010828 CHEMBL99331::N-{4-[4-(2-Hydroxy-3-m-tolyloxy-propyl)-piperazin-1-yl]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 49300 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010828&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739897 103923574 CHEMBL99331 ZINC26741020 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032596 Cc1ccccc1OCC(O)CNCc1ccc(cc1)-n1ccnc1 InChI=1S/C20H23N3O2/c1-16-4-2-3-5-20(16)25-14-19(24)13-22-12-17-6-8-18(9-7-17)23-11-10-21-15-23/h2-11,15,19,22,24H,12-14H2,1H3 NZOGFGXEMJWMEH-UHFFFAOYSA-N 50010841 1-(4-Imidazol-1-yl-benzylamino)-3-o-tolyloxy-propan-2-ol::CHEMBL98773 Beta-2 adrenergic receptor Canis familiaris 1200 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010841&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739892 103923587 CHEMBL98773 ZINC26734575 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032597 CS(=O)(=O)Nc1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3 QZWUQVSQIFFFKY-UHFFFAOYSA-N 50010833 CHEMBL552615::CHEMBL99585::Ersentilide::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-methanesulfonamide; hydrochloride::N-[4-(2-Hydroxy-3-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-propoxy)-phenyl]-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 46500 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010833&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 130400 103923579 CHEMBL99585CHEMBL552615 ZINC49625988 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032599 Cc1ccccc1OCC(O)CN1CCN(CC1)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C21H29N3O4S/c1-17-5-3-4-6-21(17)28-16-20(25)15-23-11-13-24(14-12-23)19-9-7-18(8-10-19)22-29(2,26)27/h3-10,20,22,25H,11-16H2,1-2H3 HHBPPZCDEAGVIX-UHFFFAOYSA-N 50010842 CHEMBL95754::N-{4-[4-(2-Hydroxy-3-o-tolyloxy-propyl)-piperazin-1-yl]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 6600 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010842&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739901 103923588 CHEMBL95754 ZINC26723456 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032600 CS(=O)(=O)Nc1ccc(OC[C@@H](O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3/t19-/m0/s1 QZWUQVSQIFFFKY-IBGZPJMESA-N 50367951 CHEMBL1193886 Beta-2 adrenergic receptor Canis familiaris 50000 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367951&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 208932 160847053 CHEMBL1193886 ZINC49625414 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032601 OC(CNCCOc1ccc(cc1)-n1ccnc1)COc1ccccc1 InChI=1S/C20H23N3O3/c24-18(15-26-19-4-2-1-3-5-19)14-21-11-13-25-20-8-6-17(7-9-20)23-12-10-22-16-23/h1-10,12,16,18,21,24H,11,13-15H2 XMLOXOFMPHIHFN-UHFFFAOYSA-N 50010834 1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-phenoxy-propan-2-ol::CHEMBL98975 Beta-2 adrenergic receptor Canis familiaris 280 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010834&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739905 103923580 CHEMBL98975 ZINC26737285 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032602 COCCc1ccc(OCC(O)CNCc2ccc(NS(C)(=O)=O)cc2)cc1 InChI=1S/C20H28N2O5S/c1-26-12-11-16-5-9-20(10-6-16)27-15-19(23)14-21-13-17-3-7-18(8-4-17)22-28(2,24)25/h3-10,19,21-23H,11-15H2,1-2H3 JBIIIJUBMKGJTB-UHFFFAOYSA-N 50010830 CHEMBL95727::N-[4-({2-Hydroxy-3-[4-(2-methoxy-ethyl)-phenoxy]-propylamino}-methyl)-phenyl]-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 46000 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010830&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739891 103923576 CHEMBL95727 ZINC26727460 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032603 CS(=O)(=O)Nc1ccc(OCC(O)CNCc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C20H24N4O4S/c1-29(26,27)23-17-4-8-20(9-5-17)28-14-19(25)13-22-12-16-2-6-18(7-3-16)24-11-10-21-15-24/h2-11,15,19,22-23,25H,12-14H2,1H3 LGBOEQXBWBWQKT-UHFFFAOYSA-N 50010838 CHEMBL100624::N-{4-[2-Hydroxy-3-(4-imidazol-1-yl-benzylamino)-propoxy]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 26000 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010838&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739893 103923584 CHEMBL100624 ZINC26742111 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032604 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine Beta-2 adrenergic receptor Canis familiaris 17 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032605 Cc1cccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)c1 InChI=1S/C21H25N3O3/c1-17-3-2-4-21(13-17)27-15-19(25)14-22-10-12-26-20-7-5-18(6-8-20)24-11-9-23-16-24/h2-9,11,13,16,19,22,25H,10,12,14-15H2,1H3 YZUUILKYQVFYAE-UHFFFAOYSA-N 50010840 1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-m-tolyloxy-propan-2-ol::CHEMBL421005 Beta-2 adrenergic receptor Canis familiaris 510 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010840&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739907 103923586 CHEMBL421005 ZINC26726566 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032606 CS(=O)(=O)Nc1ccc(cc1)C(O)CNCCOc1ccc(cc1)-n1ccnc1 InChI=1S/C20H24N4O4S/c1-29(26,27)23-17-4-2-16(3-5-17)20(25)14-21-11-13-28-19-8-6-18(7-9-19)24-12-10-22-15-24/h2-10,12,15,20-21,23,25H,11,13-14H2,1H3 DBTRNVNGJVUGQX-UHFFFAOYSA-N 50010844 CHEMBL316868::N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-ethyl)-phenyl]-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 5700 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010844&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739908 103923590 CHEMBL316868 ZINC49683317 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032608 COCCc1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C23H29N3O4/c1-28-14-10-19-2-6-23(7-3-19)30-17-21(27)16-24-12-15-29-22-8-4-20(5-9-22)26-13-11-25-18-26/h2-9,11,13,18,21,24,27H,10,12,14-17H2,1H3 LHDUUWAMFCDNEW-UHFFFAOYSA-N 50010837 1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol::CHEMBL95457 Beta-2 adrenergic receptor Canis familiaris 4500 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010837&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739906 103923583 CHEMBL95457 ZINC26726576 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032609 CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 ZBMZVLHSJCTVON-UHFFFAOYSA-N 25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245 Beta-2 adrenergic receptor Canis familiaris 5200 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25762&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5253 56413050 63622 CHEMBL471 DB00489 7297 C07309 ZINC49552142 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032610 CS(=O)(=O)Nc1ccc(OC[C@H](O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3/t19-/m1/s1 QZWUQVSQIFFFKY-LJQANCHMSA-N 50367950 CHEMBL1192069 Beta-2 adrenergic receptor Canis familiaris 41000 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367950&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44267518 160847052 CHEMBL1192069 ZINC49625988 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032607 Cc1cccc(OCC(O)CNCc2ccc(NS(C)(=O)=O)cc2)c1 InChI=1S/C18H24N2O4S/c1-14-4-3-5-18(10-14)24-13-17(21)12-19-11-15-6-8-16(9-7-15)20-25(2,22)23/h3-10,17,19-21H,11-13H2,1-2H3 PCRICIUMMKDSIF-UHFFFAOYSA-N 50010829 CHEMBL95966::N-{4-[(2-Hydroxy-3-m-tolyloxy-propylamino)-methyl]-phenyl}-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 4400 ChEMBL 10.1021/jm00172a033 10.7270/Q2416XN5 1976812 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010829&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14739889 103923575 CHEMBL95966 ZINC26727480 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032836 CN(c1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2C)cc1)S(C)(=O)=O InChI=1S/C23H30N4O5S/c1-18-25-12-14-27(18)20-6-10-22(11-7-20)31-15-13-24-16-21(28)17-32-23-8-4-19(5-9-23)26(2)33(3,29)30/h4-12,14,21,24,28H,13,15-17H2,1-3H3 UMGITWPLWLKFLA-UHFFFAOYSA-N 50015191 CHEMBL11944::N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-imidazol-1-yl)-phenoxy]-ethylamino}-propoxy)-phenyl]-N-methyl-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015191&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14664347 103927034 CHEMBL11944 ZINC26026543 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032837 CS(=O)(=O)Nc1ccc(OC[C@H](O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3/t19-/m1/s1 QZWUQVSQIFFFKY-LJQANCHMSA-N 50015193 CHEMBL543251::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-methanesulfonamide; hydrochloride Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015193&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44267518 103927036 CHEMBL543251 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032838 Cc1nccn1-c1ccc(OCCNCC(O)COc2ccc(NS(C)(=O)=O)cc2)cc1 InChI=1S/C22H28N4O5S/c1-17-24-11-13-26(17)19-5-9-21(10-6-19)30-14-12-23-15-20(27)16-31-22-7-3-18(4-8-22)25-32(2,28)29/h3-11,13,20,23,25,27H,12,14-16H2,1-2H3 NLVFVPIEOROZTP-UHFFFAOYSA-N 50015194 CHEMBL11629::N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-imidazol-1-yl)-phenoxy]-ethylamino}-propoxy)-phenyl]-methanesulfonamide; compound with phosphoric acid Beta-2 adrenergic receptor Canis familiaris 57000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015194&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14664343 103927037 CHEMBL11629 ZINC26022712 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032839 CS(=O)(=O)Nc1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3 QZWUQVSQIFFFKY-UHFFFAOYSA-N 50010833 CHEMBL552615::CHEMBL99585::Ersentilide::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-methanesulfonamide; hydrochloride::N-[4-(2-Hydroxy-3-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-propoxy)-phenyl]-methanesulfonamide Beta-2 adrenergic receptor Canis familiaris 47000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010833&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 130400 103923579 CHEMBL99585CHEMBL552615 ZINC49625988 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032840 CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 ZBMZVLHSJCTVON-UHFFFAOYSA-N 25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245 Beta-2 adrenergic receptor Canis familiaris 5000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25762&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5253 56413050 63622 CHEMBL471 DB00489 7297 C07309 ZINC49552142 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032841 CS(=O)(=O)Nc1ccc(OC[C@@H](O)CNCCOc2ccc(cc2)-n2ccnc2)cc1 InChI=1S/C21H26N4O5S/c1-31(27,28)24-17-2-6-21(7-3-17)30-15-19(26)14-22-11-13-29-20-8-4-18(5-9-20)25-12-10-23-16-25/h2-10,12,16,19,22,24,26H,11,13-15H2,1H3/t19-/m0/s1 QZWUQVSQIFFFKY-IBGZPJMESA-N 50015195 CHEMBL545363::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-methanesulfonamide; hydrochloride Beta-2 adrenergic receptor Canis familiaris 100000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015195&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 208932 103927038 CHEMBL545363 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032842 CC(C)(COc1ccc(cc1)-n1ccnc1)NCC(O)COc1ccc(NS(C)(=O)=O)cc1 InChI=1S/C23H30N4O5S/c1-23(2,16-32-22-10-6-19(7-11-22)27-13-12-24-17-27)25-14-20(28)15-31-21-8-4-18(5-9-21)26-33(3,29)30/h4-13,17,20,25-26,28H,14-16H2,1-3H3 DFMWOTVQIINEOY-UHFFFAOYSA-N 50015190 CHEMBL536800::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-1,1-dimethyl-ethylamino]-propoxy}-phenyl)-methanesulfonamidecompound with 2mol of HCl and 1mol of water Beta-2 adrenergic receptor Canis familiaris 23000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015190&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14664348 103927033 CHEMBL536800 ZINC26024938 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50032843 CN(c1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1)S(C)(=O)=O InChI=1S/C22H28N4O5S/c1-25(32(2,28)29)18-3-7-22(8-4-18)31-16-20(27)15-23-12-14-30-21-9-5-19(6-10-21)26-13-11-24-17-26/h3-11,13,17,20,23,27H,12,14-16H2,1-2H3 XYTXLQMEOKUFHD-UHFFFAOYSA-N 50015196 CHEMBL542544::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-N-methyl-methanesulfonamidecompound with 2mol of HCl Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm00166a002 10.7270/Q2DB82FG 2319556 Morgan, TK; Lis, R; Lumma, WC; Wohl, RA; Nickisch, K; Phillips, GB; Lind, JM; Lampe, JW; Di Meo, SV; Reiser, HJ Berlex Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015196&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14664345 103927039 CHEMBL542544 ZINC26024542 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109654 CC(C)(C)c1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 InChI=1S/C20H30N2O2/c1-20(2,3)16-8-10-17(11-9-16)21-12-18(23)13-24-22-19(14-4-5-14)15-6-7-15/h8-11,14-15,18,21,23H,4-7,12-13H2,1-3H3 BZZGFQBQMDECGA-UHFFFAOYSA-N 50064205 CHEMBL42117::Dicyclopropyl-methanone O-[3-(4-tert-butyl-phenylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064205&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288749 103959271 CHEMBL42117 ZINC11422394 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109655 OC(CNc1ccc(cc1)-c1ccccc1)CON=C(C1CC1)C1CC1 InChI=1S/C22H26N2O2/c25-21(15-26-24-22(18-6-7-18)19-8-9-19)14-23-20-12-10-17(11-13-20)16-4-2-1-3-5-16/h1-5,10-13,18-19,21,23,25H,6-9,14-15H2 HEULEACPNLSMRD-UHFFFAOYSA-N 50064204 CHEMBL295241::Dicyclopropyl-methanone O-[3-(biphenyl-4-ylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064204&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10528205 103959270 CHEMBL295241 ZINC11422306 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109657 Cc1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 InChI=1S/C17H24N2O2/c1-12-2-8-15(9-3-12)18-10-16(20)11-21-19-17(13-4-5-13)14-6-7-14/h2-3,8-9,13-14,16,18,20H,4-7,10-11H2,1H3 PSGKNQMWAGNGKK-UHFFFAOYSA-N 50064207 CHEMBL40217::Dicyclopropyl-methanone O-(2-hydroxy-3-p-tolylamino-propyl)-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064207&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288217 103959273 CHEMBL40217 ZINC11422372 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109659 Cc1cccc(NCC(O)CON=C(C2CC2)C2CC2)n1 InChI=1S/C16H23N3O2/c1-11-3-2-4-15(18-11)17-9-14(20)10-21-19-16(12-5-6-12)13-7-8-13/h2-4,12-14,20H,5-10H2,1H3,(H,17,18) RZBZPAUBGMETSI-UHFFFAOYSA-N 50064209 CHEMBL40436::Dicyclopropyl-methanone O-[2-hydroxy-3-(6-methyl-pyridin-2-ylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064209&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10520135 103959275 CHEMBL40436 ZINC13779462 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109660 CC(C)(N)Cc1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 InChI=1S/C20H31N3O2/c1-20(2,21)11-14-3-9-17(10-4-14)22-12-18(24)13-25-23-19(15-5-6-15)16-7-8-16/h3-4,9-10,15-16,18,22,24H,5-8,11-13,21H2,1-2H3 IZTIDAFZDKVBPR-UHFFFAOYSA-N 50064210 CHEMBL43046::Dicyclopropyl-methanone O-{3-[4-(2-amino-2-methyl-propyl)-phenylamino]-2-hydroxy-propyl}-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064210&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833746 103959276 CHEMBL43046 ZINC11422398 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109662 OC(CNc1ccccc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H22N2O2/c19-15(10-17-14-4-2-1-3-5-14)11-20-18-16(12-6-7-12)13-8-9-13/h1-5,12-13,15,17,19H,6-11H2 GSIGPJDONPHBRD-UHFFFAOYSA-N 50064213 CHEMBL42895::Dicyclopropylmethanone O-(3-anilino-2-hydroxypropyl)oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064213&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10039019 103959279 CHEMBL42895 ZINC11422334 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109663 Cc1cccc(NCC(O)CON=C(C2CC2)C2CC2)c1 InChI=1S/C17H24N2O2/c1-12-3-2-4-15(9-12)18-10-16(20)11-21-19-17(13-5-6-13)14-7-8-14/h2-4,9,13-14,16,18,20H,5-8,10-11H2,1H3 JMHIJHUNGQUPOA-UHFFFAOYSA-N 50064206 CHEMBL44711::Dicyclopropyl-methanone O-(2-hydroxy-3-m-tolylamino-propyl)-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064206&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496243 103959272 CHEMBL44711 ZINC11422374 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109664 OC(CNc1ccc(cc1)C(F)(F)F)CON=C(C1CC1)C1CC1 InChI=1S/C17H21F3N2O2/c18-17(19,20)13-5-7-14(8-6-13)21-9-15(23)10-24-22-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,21,23H,1-4,9-10H2 ATQWRWLPKWOPMP-UHFFFAOYSA-N 50064214 CHEMBL42337::Dicyclopropyl-methanone O-[2-hydroxy-3-(4-trifluoromethyl-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064214&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10523732 103959280 CHEMBL42337 ZINC11422480 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109667 OC(CNc1nc2ccccc2s1)CON=C(C1CC1)C1CC1 InChI=1S/C17H21N3O2S/c21-13(10-22-20-16(11-5-6-11)12-7-8-12)9-18-17-19-14-3-1-2-4-15(14)23-17/h1-4,11-13,21H,5-10H2,(H,18,19) PYPOMZTYAJHLIY-UHFFFAOYSA-N 50064215 CHEMBL288624::Dicyclopropyl-methanone O-[3-(benzothiazol-2-ylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064215&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042340 103959281 CHEMBL288624 ZINC11422295 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109668 OC(CNc1ccc(Br)cc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H21BrN2O2/c17-13-5-7-14(8-6-13)18-9-15(20)10-21-19-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,18,20H,1-4,9-10H2 AJFXKFBDRMAYOU-UHFFFAOYSA-N 50064216 CHEMBL43757::Dicyclopropyl-methanone O-[3-(4-bromo-phenylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064216&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10672010 103959282 CHEMBL43757 ZINC11422336 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109669 CCOC(=O)c1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 InChI=1S/C19H26N2O4/c1-2-24-19(23)15-7-9-16(10-8-15)20-11-17(22)12-25-21-18(13-3-4-13)14-5-6-14/h7-10,13-14,17,20,22H,2-6,11-12H2,1H3 YDNOFAGFCRMODD-UHFFFAOYSA-N 50064218 4-(3-Dicyclopropylmethyleneaminooxy-2-hydroxy-propylamino)-benzoic acid ethyl ester::CHEMBL415888 Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064218&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762496 103959284 CHEMBL415888 ZINC11422489 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109670 Cc1ccnc(NCC(O)CON=C(C2CC2)C2CC2)c1 InChI=1S/C16H23N3O2/c1-11-6-7-17-15(8-11)18-9-14(20)10-21-19-16(12-2-3-12)13-4-5-13/h6-8,12-14,20H,2-5,9-10H2,1H3,(H,17,18) FZXIMNBELHTUKV-UHFFFAOYSA-N 50064219 CHEMBL43061::Dicyclopropyl-methanone O-[2-hydroxy-3-(4-methyl-pyridin-2-ylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064219&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835117 103959285 CHEMBL43061 ZINC11422381 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109672 OC(CNc1ccc(I)cc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H21IN2O2/c17-13-5-7-14(8-6-13)18-9-15(20)10-21-19-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,18,20H,1-4,9-10H2 HYMRIWGOEMUUFN-UHFFFAOYSA-N 50064212 CHEMBL44261::Dicyclopropyl-methanone O-[2-hydroxy-3-(4-iodo-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris 10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064212&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10553898 103959278 CHEMBL44261 ZINC11422482 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109675 OC(CNc1ccc(cc1)[N+]([O-])=O)CO[N-][C+](C1CC1)C1CC1 InChI=1S/C16H21N3O4/c20-15(9-17-13-5-7-14(8-6-13)19(21)22)10-23-18-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,17,20H,1-4,9-10H2 OLEJEALYPUAWNW-UHFFFAOYSA-N 50064221 CHEMBL289309::Dicyclopropyl-methanone O-[2-hydroxy-3-(4-nitro-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064221&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765323 103959287 CHEMBL289309 ZINC11422343 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109677 OC(CNc1ccccn1)CON=C(C1CC1)C1CC1 InChI=1S/C15H21N3O2/c19-13(9-17-14-3-1-2-8-16-14)10-20-18-15(11-4-5-11)12-6-7-12/h1-3,8,11-13,19H,4-7,9-10H2,(H,16,17) DJGNUIYWRRODTA-UHFFFAOYSA-N 50064223 CHEMBL40272::Dicyclopropyl-methanone O-[2-hydroxy-3-(pyridin-2-ylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064223&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10778795 103959289 CHEMBL40272 ZINC11422359 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109681 CCCCc1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 InChI=1S/C20H30N2O2/c1-2-3-4-15-5-11-18(12-6-15)21-13-19(23)14-24-22-20(16-7-8-16)17-9-10-17/h5-6,11-12,16-17,19,21,23H,2-4,7-10,13-14H2,1H3 YWADUFGFKKNNDJ-UHFFFAOYSA-N 50064224 CHEMBL42792::Dicyclopropyl-methanone O-[3-(4-butyl-phenylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064224&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618945 103959290 CHEMBL42792 ZINC11422396 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109689 OC(CNc1ccccc1I)CON=C(C1CC1)C1CC1 InChI=1S/C16H21IN2O2/c17-14-3-1-2-4-15(14)18-9-13(20)10-21-19-16(11-5-6-11)12-7-8-12/h1-4,11-13,18,20H,5-10H2 BTHPOKAPWFMVTO-UHFFFAOYSA-N 50064225 CHEMBL44396::Dicyclopropyl-methanone O-[2-hydroxy-3-(2-iodo-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064225&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797214 103959291 CHEMBL44396 ZINC11422483 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109696 Cc1ccccc1NCC(O)CON=C(C1CC1)C1CC1 InChI=1S/C17H24N2O2/c1-12-4-2-3-5-16(12)18-10-15(20)11-21-19-17(13-6-7-13)14-8-9-14/h2-5,13-15,18,20H,6-11H2,1H3 AZJJSKOUHVSHNT-UHFFFAOYSA-N 50064208 CHEMBL40679::Dicyclopropyl-methanone O-(2-hydroxy-3-o-tolylamino-propyl)-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064208&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643362 103959274 CHEMBL40679 ZINC11422376 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109702 OC(CNc1ccc(Cl)cc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H21ClN2O2/c17-13-5-7-14(8-6-13)18-9-15(20)10-21-19-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,18,20H,1-4,9-10H2 BJPHVYNGLCVIPQ-UHFFFAOYSA-N 50064228 CHEMBL296093::Dicyclopropyl-methanone O-[3-(4-chloro-phenylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064228&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764829 103959294 CHEMBL296093 ZINC13779464 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109704 OC(CNc1nc2ccccc2[nH]1)CON=C(C1CC1)C1CC1 InChI=1S/C17H22N4O2/c22-13(10-23-21-16(11-5-6-11)12-7-8-12)9-18-17-19-14-3-1-2-4-15(14)20-17/h1-4,11-13,22H,5-10H2,(H2,18,19,20) ZQIPEWCLUZKOGR-UHFFFAOYSA-N 50064217 CHEMBL43850::Dicyclopropyl-methanone O-[3-(1H-benzoimidazol-2-ylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064217&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288489 103959283 CHEMBL43850 ZINC11422297 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109706 CC(C)(Cc1ccc(NCC(O)CO[N-][C+](C2CC2)C2CC2)cc1)[N+]([O-])=O InChI=1S/C20H29N3O4/c1-20(2,23(25)26)11-14-3-9-17(10-4-14)21-12-18(24)13-27-22-19(15-5-6-15)16-7-8-16/h3-4,9-10,15-16,18,21,24H,5-8,11-13H2,1-2H3 LAYFYVAWRJMLET-UHFFFAOYSA-N 50064220 CHEMBL42267::Dicyclopropyl-methanone O-{2-hydroxy-3-[4-(2-methyl-2-nitro-propyl)-phenylamino]-propyl}-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064220&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549600 103959286 CHEMBL42267 ZINC11422400 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109708 OC(CNc1cccc(I)c1)CON=C(C1CC1)C1CC1 InChI=1S/C16H21IN2O2/c17-13-2-1-3-14(8-13)18-9-15(20)10-21-19-16(11-4-5-11)12-6-7-12/h1-3,8,11-12,15,18,20H,4-7,9-10H2 GMZATGRCGRFPLK-UHFFFAOYSA-N 50064227 CHEMBL40412::Dicyclopropyl-methanone O-[2-hydroxy-3-(3-iodo-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064227&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525002 103959293 CHEMBL40412 ZINC11422330 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109718 Cc1ccc(NCC(O)CON=C(C2CC2)C2CC2)nc1 InChI=1S/C16H23N3O2/c1-11-2-7-15(17-8-11)18-9-14(20)10-21-19-16(12-3-4-12)13-5-6-13/h2,7-8,12-14,20H,3-6,9-10H2,1H3,(H,17,18) PFVWZGCVLFKNET-UHFFFAOYSA-N 50064231 CHEMBL297382::Dicyclopropyl-methanone O-[2-hydroxy-3-(5-methyl-pyridin-2-ylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064231&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10520137 103959297 CHEMBL297382 ZINC13779463 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109719 OC(CNc1ccc(O)cc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H22N2O3/c19-14-7-5-13(6-8-14)17-9-15(20)10-21-18-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,17,19-20H,1-4,9-10H2 HRVKVTBHWKBKBC-UHFFFAOYSA-N 50064229 CHEMBL42144::Dicyclopropyl-methanone O-[2-hydroxy-3-(4-hydroxy-phenylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064229&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544155 103959295 CHEMBL42144 ZINC11422345 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109720 CN(CC(O)CON=C(C1CC1)C1CC1)c1ccccc1 InChI=1S/C17H24N2O2/c1-19(15-5-3-2-4-6-15)11-16(20)12-21-18-17(13-7-8-13)14-9-10-14/h2-6,13-14,16,20H,7-12H2,1H3 ZJOXSNGTCIQTEK-UHFFFAOYSA-N 50064232 CHEMBL288541::Dicyclopropyl-methanone O-[2-hydroxy-3-(methyl-phenyl-amino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064232&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732112 103959298 CHEMBL288541 ZINC11422491 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109724 OC(CNc1ccccc1-c1ccccc1)CON=C(C1CC1)C1CC1 InChI=1S/C22H26N2O2/c25-19(15-26-24-22(17-10-11-17)18-12-13-18)14-23-21-9-5-4-8-20(21)16-6-2-1-3-7-16/h1-9,17-19,23,25H,10-15H2 KNCNOSADGGQHIX-UHFFFAOYSA-N 50064230 CHEMBL290024::Dicyclopropyl-methanone O-[3-(biphenyl-2-ylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064230&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596336 103959296 CHEMBL290024 ZINC11422308 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109725 OC(CNc1ccncc1)CON=C(C1CC1)C1CC1 InChI=1S/C15H21N3O2/c19-14(9-17-13-5-7-16-8-6-13)10-20-18-15(11-1-2-11)12-3-4-12/h5-8,11-12,14,19H,1-4,9-10H2,(H,16,17) LAYHIVACOPNUOL-UHFFFAOYSA-N 50064211 CHEMBL43111::Dicyclopropyl-methanone O-[2-hydroxy-3-(pyridin-4-ylamino)-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064211&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10636130 103959277 CHEMBL43111 ZINC11422362 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109726 CC(C)(Cc1ccc(N)cc1)NCC(O)CON=C(C1CC1)C1CC1 InChI=1S/C20H31N3O2/c1-20(2,11-14-3-9-17(21)10-4-14)22-12-18(24)13-25-23-19(15-5-6-15)16-7-8-16/h3-4,9-10,15-16,18,22,24H,5-8,11-13,21H2,1-2H3 OMJNSZGKDGPODS-UHFFFAOYSA-N 50064233 CHEMBL41149::Dicyclopropyl-methanone O-{3-[2-(4-amino-phenyl)-1,1-dimethyl-ethylamino]-2-hydroxy-propyl}-oxime Beta-2 adrenergic receptor Canis familiaris 2000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064233&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10545491 103959299 CHEMBL41149 ZINC11422402 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109727 OC(CNc1ccc(F)cc1)CON=C(C1CC1)C1CC1 InChI=1S/C16H21FN2O2/c17-13-5-7-14(8-6-13)18-9-15(20)10-21-19-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,18,20H,1-4,9-10H2 SLAIRFMBJZDINS-UHFFFAOYSA-N 50064222 CHEMBL290150::Dicyclopropyl-methanone O-[3-(4-fluoro-phenylamino)-2-hydroxy-propyl]-oxime Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064222&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597567 103959288 CHEMBL290150 ZINC11422339 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109729 CC(C)(Cc1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1)NCC(O)CON=C(C1CC1)C1CC1 InChI=1S/C30H46N4O4/c1-30(2,32-17-27(36)19-38-34-29(23-9-10-23)24-11-12-24)15-20-3-13-25(14-4-20)31-16-26(35)18-37-33-28(21-5-6-21)22-7-8-22/h3-4,13-14,21-24,26-27,31-32,35-36H,5-12,15-19H2,1-2H3 YJNWNNYHWWXCOY-UHFFFAOYSA-N 50064234 CHEMBL41628::Dicyclopropyl-methanone O-(3-{2-[4-(3-dicyclopropylmethyleneaminooxy-2-hydroxy-propylamino)-phenyl]-1,1-dimethyl-ethylamino}-2-hydroxy-propyl)-oxime Beta-2 adrenergic receptor Canis familiaris 1500 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064234&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10673684 103959300 CHEMBL41628 ZINC13779468 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50109736 OC(CNc1ccc(cc1)C(O)=O)CON=C(C1CC1)C1CC1 InChI=1S/C17H22N2O4/c20-15(9-18-14-7-5-13(6-8-14)17(21)22)10-23-19-16(11-1-2-11)12-3-4-12/h5-8,11-12,15,18,20H,1-4,9-10H2,(H,21,22) SQEHZTLPVBRNLR-UHFFFAOYSA-N 50064226 4-(3-Dicyclopropylmethyleneaminooxy-2-hydroxy-propylamino)-benzoic acid::CHEMBL42665 Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1021/jm970338c 10.7270/Q2416W5G 9572886 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P University of Grenoble http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064226&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797082 103959292 CHEMBL42665 ZINC11422481 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154330 COc1ccccc1N1CCN(CC(O)COc2ccc3SCC(=O)Nc3c2)CC1 InChI=1S/C22H27N3O4S/c1-28-20-5-3-2-4-19(20)25-10-8-24(9-11-25)13-16(26)14-29-17-6-7-21-18(12-17)23-22(27)15-30-21/h2-7,12,16,26H,8-11,13-15H2,1H3,(H,23,27) QXTUOYRGOXEKPL-UHFFFAOYSA-N 50086677 6-{2-Hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL142474 Beta-2 adrenergic receptor Canis familiaris 4000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086677&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361723 103985862 CHEMBL142474 ZINC27524974 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154343 OC(COc1ccc2SCC(=O)Nc2c1)CN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C21H24FN3O3S/c22-15-1-3-16(4-2-15)25-9-7-24(8-10-25)12-17(26)13-28-18-5-6-20-19(11-18)23-21(27)14-29-20/h1-6,11,17,26H,7-10,12-14H2,(H,23,27) NYHDZOLJPWXMLQ-UHFFFAOYSA-N 50086663 6-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL143608 Beta-2 adrenergic receptor Canis familiaris 5300 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086663&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361630 103985848 CHEMBL143608 ZINC27524080 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154344 OC(COc1ccc2NC(=O)CSc2c1)CN1CCN(CC1)C(=O)c1ccc(F)cc1 InChI=1S/C22H24FN3O4S/c23-16-3-1-15(2-4-16)22(29)26-9-7-25(8-10-26)12-17(27)13-30-18-5-6-19-20(11-18)31-14-21(28)24-19/h1-6,11,17,27H,7-10,12-14H2,(H,24,28) WIDNJWUXNYEJOQ-UHFFFAOYSA-N 50086678 7-{3-[4-(4-Fluoro-benzoyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL342061 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086678&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361636 103985863 CHEMBL342061 ZINC27524171 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154347 CC(C)(C)NCC(O)COc1cccc2NC(=O)CSc12 InChI=1S/C15H22N2O3S/c1-15(2,3)16-7-10(18)8-20-12-6-4-5-11-14(12)21-9-13(19)17-11/h4-6,10,16,18H,7-9H2,1-3H3,(H,17,19) SWWQDUZAPYPHEI-UHFFFAOYSA-N 50086673 8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1,4]thiazin-3-one::CHEMBL140908 Beta-2 adrenergic receptor Canis familiaris 23 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086673&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 131645 103985858 CHEMBL140908 ZINC05353243 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154352 OC(COc1ccc2SCC(=O)Nc2c1)CN1CCN(CC1)C(=O)c1ccco1 InChI=1S/C20H23N3O5S/c24-14(12-28-15-3-4-18-16(10-15)21-19(25)13-29-18)11-22-5-7-23(8-6-22)20(26)17-2-1-9-27-17/h1-4,9-10,14,24H,5-8,11-13H2,(H,21,25) OZSDSLANSUSJIQ-UHFFFAOYSA-N 50086674 6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL141184 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086674&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361461 103985859 CHEMBL141184 ZINC27523270 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154355 OC(COc1cccc2NC(=O)CSc12)CN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C21H24FN3O3S/c22-15-4-6-16(7-5-15)25-10-8-24(9-11-25)12-17(26)13-28-19-3-1-2-18-21(19)29-14-20(27)23-18/h1-7,17,26H,8-14H2,(H,23,27) PGAIECSQNAEQMI-UHFFFAOYSA-N 50086679 8-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL142995 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086679&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361634 103985864 CHEMBL142995 ZINC27524168 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154356 COc1ccccc1N1CCN(CCCN2C(=O)CSc3c(OCC(O)CNC(C)(C)C)cccc23)CC1 InChI=1S/C29H42N4O4S/c1-29(2,3)30-19-22(34)20-37-26-12-7-10-24-28(26)38-21-27(35)33(24)14-8-13-31-15-17-32(18-16-31)23-9-5-6-11-25(23)36-4/h5-7,9-12,22,30,34H,8,13-21H2,1-4H3 UORFXDKDNXZABJ-UHFFFAOYSA-N 50086666 8-(3-tert-Butylamino-2-hydroxy-propoxy)-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-4H-benzo[1,4]thiazin-3-one::CHEMBL143463 Beta-2 adrenergic receptor Canis familiaris 2.7 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086666&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 9984829 103985851 CHEMBL143463 ZINC27524065 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154364 OC(COc1cccc2NC(=O)CSc12)CN1CCN(CC1)C(=O)c1ccc(F)cc1 InChI=1S/C22H24FN3O4S/c23-16-6-4-15(5-7-16)22(29)26-10-8-25(9-11-26)12-17(27)13-30-19-3-1-2-18-21(19)31-14-20(28)24-18/h1-7,17,27H,8-14H2,(H,24,28) HGLMWLKCPYICHB-UHFFFAOYSA-N 50086675 8-{3-[4-(4-Fluoro-benzoyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL142496 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086675&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361774 103985860 CHEMBL142496 ZINC27525979 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154365 OC(COc1cccc2NC(=O)CSc12)CN1CCN(CC1)C(=O)c1ccco1 InChI=1S/C20H23N3O5S/c24-14(12-28-16-4-1-3-15-19(16)29-13-18(25)21-15)11-22-6-8-23(9-7-22)20(26)17-5-2-10-27-17/h1-5,10,14,24H,6-9,11-13H2,(H,21,25) QYZZNVKHUWLQBM-UHFFFAOYSA-N 50086664 8-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL143679 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086664&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361789 103985849 CHEMBL143679 ZINC27524638 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154366 COc1ccccc1N1CCN(CC(O)COc2cccc3NC(=O)CSc23)CC1 InChI=1S/C22H27N3O4S/c1-28-19-7-3-2-6-18(19)25-11-9-24(10-12-25)13-16(26)14-29-20-8-4-5-17-22(20)30-15-21(27)23-17/h2-8,16,26H,9-15H2,1H3,(H,23,27) RWCYXZFXVVZWCH-UHFFFAOYSA-N 50086670 8-{2-Hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL341614 Beta-2 adrenergic receptor Canis familiaris 88 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086670&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361777 103985855 CHEMBL341614 ZINC27524765 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154373 OC(COc1ccc2NC(=O)CSc2c1)CN1CCN(CC1)C(=O)c1ccco1 InChI=1S/C20H23N3O5S/c24-14(12-28-15-3-4-16-18(10-15)29-13-19(25)21-16)11-22-5-7-23(8-6-22)20(26)17-2-1-9-27-17/h1-4,9-10,14,24H,5-8,11-13H2,(H,21,25) CJCYZIHADIQBRT-UHFFFAOYSA-N 50086672 7-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL143733 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086672&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361790 103985857 CHEMBL143733 ZINC27524640 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155793 NC[C@H](O)c1cc(O)c(O)cc1F InChI=1S/C8H10FNO3/c9-5-2-7(12)6(11)1-4(5)8(13)3-10/h1-2,8,11-13H,3,10H2/t8-/m0/s1 SBUQBFTXTZSRMH-QMMMGPOBSA-N 50087513 (R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol::2-fluoronorepinehprine::CHEMBL40317 Beta-2 adrenergic receptor Canis familiaris 28000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087513&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603724 103986560 CHEMBL40317 ZINC02539810 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155794 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 Beta-2 adrenergic receptor Canis familiaris 50000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155795 CNC[C@@H](O)c1ccc(O)c(O)c1F InChI=1S/C9H12FNO3/c1-11-4-7(13)5-2-3-6(12)9(14)8(5)10/h2-3,7,11-14H,4H2,1H3/t7-/m1/s1 HGZKLMFEVVYGMO-SSDOTTSWSA-N 50087514 (S)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::CHEMBL295651 Beta-2 adrenergic receptor Canis familiaris 24000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087514&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10488284 103986561 CHEMBL295651 ZINC13807918 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155807 CNCC(O)c1ccc(O)c(O)c1F InChI=1S/C9H12FNO3/c1-11-4-7(13)5-2-3-6(12)9(14)8(5)10/h2-3,7,11-14H,4H2,1H3 HGZKLMFEVVYGMO-UHFFFAOYSA-N 50019059 (+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol(2-FEPI)::CHEMBL43711 Beta-2 adrenergic receptor Canis familiaris 260 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019059&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420352 103930101 CHEMBL43711 ZINC13807918 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155812 NCC(O)c1cc(O)c(O)cc1F InChI=1S/C8H10FNO3/c9-5-2-7(12)6(11)1-4(5)8(13)3-10/h1-2,8,11-13H,3,10H2 SBUQBFTXTZSRMH-UHFFFAOYSA-N 50019061 (+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol::4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol::4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol(6-FNE)::CHEMBL281232 Beta-2 adrenergic receptor Canis familiaris 58000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019061&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 1862 103930103 CHEMBL281232 510 ZINC03871196 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155815 NC[C@H](O)c1ccc(O)c(O)c1F InChI=1S/C8H10FNO3/c9-7-4(6(12)3-10)1-2-5(11)8(7)13/h1-2,6,11-13H,3,10H2/t6-/m0/s1 FOTRTWXNJQSQJS-LURJTMIESA-N 50087518 (R)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol::6-fluoronorepinehprine::CHEMBL295072 Beta-2 adrenergic receptor Canis familiaris 67 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087518&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10352428 103986565 CHEMBL295072 ZINC06091773 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155816 CNC[C@H](O)c1cc(O)c(O)cc1F InChI=1S/C9H12FNO3/c1-11-4-9(14)5-2-7(12)8(13)3-6(5)10/h2-3,9,11-14H,4H2,1H3/t9-/m0/s1 DKBXREAGJFVVAP-VIFPVBQESA-N 50087515 (R)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::CHEMBL40986 Beta-2 adrenergic receptor Canis familiaris 38000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087515&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10774431 103986562 CHEMBL40986 ZINC13807919 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155819 CNC[C@H](O)c1ccc(O)c(O)c1 InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1 UCTWMZQNUQWSLP-VIFPVBQESA-N 50029050 (-)-(R)-epinephrine::(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol::(-)-adrenaline::(R)-(-)-adrenaline::(R)-adrenaline::4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::Adrenalin::CHEMBL679::EPINEPHRINE::adrenaline::levoepinephrine Beta-2 adrenergic receptor Canis familiaris 660.0 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029050&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search ALE 7BTS,4A7U,7BRN,2HKK,4LDO 5816 103938164 28918 CHEMBL679 DB00668 479 C02012 ZINC00039089 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155822 NCC(O)c1ccc(O)c(O)c1F InChI=1S/C8H10FNO3/c9-7-4(6(12)3-10)1-2-5(11)8(7)13/h1-2,6,11-13H,3,10H2 FOTRTWXNJQSQJS-UHFFFAOYSA-N 50019060 (+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol::4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol::4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol(2-FNE)::CHEMBL287587 Beta-2 adrenergic receptor Canis familiaris 140 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019060&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 172745 103930102 CHEMBL287587 ZINC06091773 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155825 CNC[C@H](O)c1ccc(O)c(O)c1F InChI=1S/C9H12FNO3/c1-11-4-7(13)5-2-3-6(12)9(14)8(5)10/h2-3,7,11-14H,4H2,1H3/t7-/m0/s1 HGZKLMFEVVYGMO-ZETCQYMHSA-N 50087520 (R)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::CHEMBL42370 Beta-2 adrenergic receptor Canis familiaris 110 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087520&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10512270 103986567 CHEMBL42370 ZINC11422476 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155829 CNCC(O)c1cc(O)c(O)cc1F InChI=1S/C9H12FNO3/c1-11-4-9(14)5-2-7(12)8(13)3-6(5)10/h2-3,9,11-14H,4H2,1H3 DKBXREAGJFVVAP-UHFFFAOYSA-N 50019057 (+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol::4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol(6-FEPI)::CHEMBL42359 Beta-2 adrenergic receptor Canis familiaris 50000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019057&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 541604 103930099 CHEMBL42359 ZINC13807919 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155833 NC[C@H](O)c1ccc(O)c(O)c1 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 50029051 (-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE Beta-2 adrenergic receptor Canis familiaris 11000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search LNR 3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH 439260 103938165 18357 CHEMBL1437 DB00368 505 C00547 ZINC00057624 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155845 CNC[C@@H](O)c1ccc(O)c(O)c1 InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m1/s1 UCTWMZQNUQWSLP-SECBINFHSA-N 50087512 (+)-adrenaline::(S)-adrenaline::CHEMBL42280 Beta-2 adrenergic receptor Canis familiaris 3700 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087512&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search XDE 3PAH 247704 103986559 33568 CHEMBL42280 4450 C02012 ZINC00039090 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50155846 NC[C@@H](O)c1ccc(O)c(O)c1F InChI=1S/C8H10FNO3/c9-7-4(6(12)3-10)1-2-5(11)8(7)13/h1-2,6,11-13H,3,10H2/t6-/m1/s1 FOTRTWXNJQSQJS-ZCFIWIBFSA-N 50087516 (S)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol::CHEMBL40796 Beta-2 adrenergic receptor Canis familiaris 27000 ChEMBL 10.1021/jm990599h 10.7270/Q25M64ZV 10780918 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087516&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10773922 103986563 CHEMBL40796 ZINC06091770 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154300 OC(COc1ccc2SCC(=O)Nc2c1)CN1CCN(CC1)C(=O)c1ccc(F)cc1 InChI=1S/C22H24FN3O4S/c23-16-3-1-15(2-4-16)22(29)26-9-7-25(8-10-26)12-17(27)13-30-18-5-6-20-19(11-18)24-21(28)14-31-20/h1-6,11,17,27H,7-10,12-14H2,(H,24,28) NTSJCWZFZFAXEP-UHFFFAOYSA-N 50086660 6-{3-[4-(4-Fluoro-benzoyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL142912 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086660&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361775 103985845 CHEMBL142912 ZINC27525982 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154302 COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1 InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3 HRRBJVNMSRJFHQ-UHFFFAOYSA-N 50773 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthalenyloxy)-2-propanol;hydrochloride::1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxy-propan-2-ol;hydrochloride::1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;hydrochloride::1-[4-(2-methoxyphenyl)piperazino]-3-(1-naphthoxy)propan-2-ol;hydrochloride::CHEMBL142635::MLS000069363::NAFTOPIDIL DIHYDROCHLORIDE::SMR000058489::cid_4418::cid_6603044 Beta-2 adrenergic receptor Canis familiaris 1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50773&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 4418 252631028 CHEMBL142635 ZINC04140721 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154305 OC(COc1ccc2NC(=O)CSc2c1)CN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C21H24FN3O3S/c22-15-1-3-16(4-2-15)25-9-7-24(8-10-25)12-17(26)13-28-18-5-6-19-20(11-18)29-14-21(27)23-19/h1-6,11,17,26H,7-10,12-14H2,(H,23,27) ASDLXXUOHBNMMC-UHFFFAOYSA-N 50086665 7-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL143944 Beta-2 adrenergic receptor Canis familiaris 4800 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086665&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361776 103985850 CHEMBL143944 ZINC27524689 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154311 COc1ccccc1N1CCN(CC(O)COc2ccc3NC(=O)CSc3c2)CC1 InChI=1S/C22H27N3O4S/c1-28-20-5-3-2-4-19(20)25-10-8-24(9-11-25)13-16(26)14-29-17-6-7-18-21(12-17)30-15-22(27)23-18/h2-7,12,16,26H,8-11,13-15H2,1H3,(H,23,27) GNBNOEIICSAQHH-UHFFFAOYSA-N 50086668 7-{2-Hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL142948 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086668&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361936 103985853 CHEMBL142948 ZINC27524986 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50154313 COc1ccccc1N1CCN(CCCN2C(=O)CSc3ccccc23)CC1 InChI=1S/C22H27N3O2S/c1-27-20-9-4-2-7-18(20)24-15-13-23(14-16-24)11-6-12-25-19-8-3-5-10-21(19)28-17-22(25)26/h2-5,7-10H,6,11-17H2,1H3 QEEWJKZQASXBDH-UHFFFAOYSA-N 50086662 4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-4H-benzo[1,4]thiazin-3-one::CHEMBL143397 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1016/s0960-894x(00)00016-0 10.7270/Q2SJ1JVG 10743949 Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A Università di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086662&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361637 103985847 CHEMBL143397 ZINC27524233 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50474995 O[C@@H](CN[C@H]1CCCc2cc3OC(Oc3cc2C1)(C([O-])=O)C([O-])=O)c1cccc(Cl)c1 InChI=1S/C22H22ClNO7/c23-15-5-1-4-13(7-15)17(25)11-24-16-6-2-3-12-9-18-19(10-14(12)8-16)31-22(30-18,20(26)27)21(28)29/h1,4-5,7,9-10,16-17,24-25H,2-3,6,8,11H2,(H,26,27)(H,28,29)/p-2/t16-,17-/m0/s1 GWMSTQYZVVPMPN-IRXDYDNUSA-L 50285930 CHEMBL421193::Disodium salt of (S)-6-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-6,7,8,9-tetrahydro-5H-1,3-dioxa-cyclohepta[f]indene-2,2-dicarboxylic acid::FR-165914 Beta-2 adrenergic receptor Canis familiaris >10000 ChEMBL 10.1016/0960-894X(95)00483-A 10.7270/Q2PC32B2 Hattori, K; Nagano, M; Kato, T; Nakanishi, I; Imai, K; Kinoshita, T; Sakane, K TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50285930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50285930&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 91934834 104127501 CHEMBL421193 ZINC03824081 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50724883 COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12 InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1 MHPMXTGKTXJIDI-IBGZPJMESA-N 50057128 (2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258 Beta-2 adrenergic receptor Canis familiaris 1740 ChEMBL 10.1016/0960-894X(95)00398-D 10.7270/Q2T72HZ0 Meyer, MD; Hancock, AA; Tietje, K; Sippy, kB; Giardina, WJ; Kerwin, JF TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928332 103953208 CHEMBL268258 ZINC03810797 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50753989 Cc1nc[nH]c1Cc1nc(cs1)-c1ccccc1 InChI=1S/C14H13N3S/c1-10-12(16-9-15-10)7-14-17-13(8-18-14)11-5-3-2-4-6-11/h2-6,8-9H,7H2,1H3,(H,15,16) SDWUPSHVUBKGKN-UHFFFAOYSA-N 50014154 2-(5-Methyl-1H-imidazol-4-ylmethyl)-4-phenyl-thiazole::CHEMBL38465 Beta-2 adrenergic receptor Canis familiaris >1000 ChEMBL 10.1021/jm00172a006 10.7270/Q2H995S5 2213824 Rosen, T; Nagel, AA; Rizzi, JP; Ives, JL; Daffeh, JB; Ganong, AH; Guarino, K; Heym, J; McLean, S; Nowakowski, JT Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014154&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 14742527 103926176 CHEMBL38465 ZINC00004346 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50756604 Cc1ccc2[C@H](CN)O[C@@H](Cc2c1O)C1CCCCC1 InChI=1S/C17H25NO2/c1-11-7-8-13-14(17(11)19)9-15(20-16(13)10-18)12-5-3-2-4-6-12/h7-8,12,15-16,19H,2-6,9-10,18H2,1H3/t15-,16-/m0/s1 HSJYTPFWWPUYDT-HOTGVXAUSA-N 50008825 1-Aminomethyl-3-cyclohexyl-6-methyl-isochroman-5-ol; hydrobromide::CHEMBL542436 Beta-2 adrenergic receptor Canis familiaris 19200 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008825&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711850 103921936 CHEMBL542436 ZINC13824652 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50756638 NC[C@@H]1O[C@@H](Cc2c(O)c(Br)ccc12)c1ccccc1 InChI=1S/C16H16BrNO2/c17-13-7-6-11-12(16(13)19)8-14(20-15(11)9-18)10-4-2-1-3-5-10/h1-7,14-15,19H,8-9,18H2/t14-,15-/m0/s1 SIPQEKQXLUBVAY-GJZGRUSLSA-N 50008824 1-Aminomethyl-6-bromo-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL543390 Beta-2 adrenergic receptor Canis familiaris 18400 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008824&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711869 103921935 CHEMBL543390 ZINC13824664 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50988251 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine Beta-2 adrenergic receptor Canis familiaris 1.78 ChEMBL 10.1021/jm00373a008 10.7270/Q22B906S 6330358 Nelson, WL; Bartels, MJ; Bednarski, PJ; Zhang, S; Messick, K; Horng, JS; Ruffolo, RR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50988248 CC(C)NCC(O)COC1=CC(=O)C(=O)c2ccccc12 InChI=1S/C16H19NO4/c1-10(2)17-8-11(18)9-21-15-7-14(19)16(20)13-6-4-3-5-12(13)15/h3-7,10-11,17-18H,8-9H2,1-2H3 IVFBLZWKXKCXRZ-UHFFFAOYSA-N 50405146 CHEMBL171432 Beta-2 adrenergic receptor Canis familiaris 29.51 ChEMBL 10.1021/jm00373a008 10.7270/Q22B906S 6330358 Nelson, WL; Bartels, MJ; Bednarski, PJ; Zhang, S; Messick, K; Horng, JS; Ruffolo, RR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405146&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381395 163354170 CHEMBL171432 ZINC27993345 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50988250 CC(C)NCC(O)COc1ccc(O)c2ccccc12 InChI=1S/C16H21NO3/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16/h3-8,11-12,17-19H,9-10H2,1-2H3 CWEPACWBWIOYID-UHFFFAOYSA-N 50405147 4-HYDROXYPROPRANOLOL SULFATE::4-Hydroxy Propranolol Beta-2 adrenergic receptor Canis familiaris 2.4 ChEMBL 10.1021/jm00373a008 10.7270/Q22B906S 6330358 Nelson, WL; Bartels, MJ; Bednarski, PJ; Zhang, S; Messick, K; Horng, JS; Ruffolo, RR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405147&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 91565 163354171 ZINC05760515 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50999057 CC(NCCc1ccc(OCC(O)=O)c(Cl)c1)[C@H](O)c1ccc(O)cc1 InChI=1S/C19H22ClNO5/c1-12(19(25)14-3-5-15(22)6-4-14)21-9-8-13-2-7-17(16(20)10-13)26-11-18(23)24/h2-7,10,12,19,21-22,25H,8-9,11H2,1H3,(H,23,24)/t12?,19-/m0/s1 YNCNZXJRRRALAJ-RKLCOFROSA-N 50122651 (alpha R,betaS) (2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid::CHEMBL14059 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122651&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269101 104015291 CHEMBL14059 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50999058 C[C@H](NCCc1ccc(OCC(O)=O)c(Cl)c1)[C@@H](O)c1ccc(O)cc1 InChI=1S/C19H22ClNO5/c1-12(19(25)14-3-5-15(22)6-4-14)21-9-8-13-2-7-17(16(20)10-13)26-11-18(23)24/h2-7,10,12,19,21-22,25H,8-9,11H2,1H3,(H,23,24)/t12-,19+/m0/s1 YNCNZXJRRRALAJ-HXPMCKFVSA-N 50409693 CHEMBL2079543 Beta-2 adrenergic receptor Canis familiaris >100000 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409693&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10981769 163358717 CHEMBL2079543 ZINC11422461 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 50998228 CC(C)NCC(O)c1ccc(O)c(O)c1 InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 JWZZKOKVBUJMES-UHFFFAOYSA-N 25392 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride::4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol::4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2::CHEMBL434::ISOPROTERONOL::Isoprenaline::Isoproterenol::Isoproterenol (-)::Isoproterenol,(+)::Isoproterenol-l::Norisodrine::Novodrin Beta-2 adrenergic receptor Canis familiaris 0.1 ChEMBL 10.1021/jm000455z 10.7270/Q2Q52QVH 11311067 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Akahane, S; Miyata, H; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25392&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5FW 7S0F,7S0G,5YTU,7JJO,4A7T,2Y03,7XJH,7DHR,6H7J 3779 56374531 64317 CHEMBL434 DB01064 536 C02012 ZINC00056653 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 51033066 CC(C)NCC(O)c1ccc(O)c(O)c1 InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 JWZZKOKVBUJMES-UHFFFAOYSA-N 25392 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride::4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol::4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2::CHEMBL434::ISOPROTERONOL::Isoprenaline::Isoproterenol::Isoproterenol (-)::Isoproterenol,(+)::Isoproterenol-l::Norisodrine::Novodrin Beta-2 adrenergic receptor Canis familiaris 0.10 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25392&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 5FW 7S0F,7S0G,5YTU,7JJO,4A7T,2Y03,7XJH,7DHR,6H7J 3779 56374531 64317 CHEMBL434 DB01064 536 C02012 ZINC00056653 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 51033067 C[C@@H](NCCc1ccc(OCC(O)=O)c(Cl)c1)[C@H](O)c1ccc(O)cc1 InChI=1S/C19H22ClNO5/c1-12(19(25)14-3-5-15(22)6-4-14)21-9-8-13-2-7-17(16(20)10-13)26-11-18(23)24/h2-7,10,12,19,21-22,25H,8-9,11H2,1H3,(H,23,24)/t12-,19+/m1/s1 YNCNZXJRRRALAJ-BLVKFPJESA-N 50422434 CHEMBL2079599 Beta-2 adrenergic receptor Canis familiaris 59979 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422434&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 10915880 164151309 CHEMBL2079599 ZINC11422462 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 51033068 CCOC(=O)COc1ccc(CCNC(C)C(O)c2ccc(O)cc2)cc1Cl InChI=1S/C21H26ClNO5/c1-3-27-20(25)13-28-19-9-4-15(12-18(19)22)10-11-23-14(2)21(26)16-5-7-17(24)8-6-16/h4-9,12,14,21,23-24,26H,3,10-11,13H2,1-2H3 OWJSVNHNFSCPRV-UHFFFAOYSA-N 50122649 (2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid ethyl ester; hydrochloride::CHEMBL544427 Beta-2 adrenergic receptor Canis familiaris 525 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122649&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 11611195 104015289 CHEMBL544427 ZINC35932890 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 51033069 C[C@@H](NCCc1ccc(OCC(O)=O)c(Cl)c1)[C@@H](O)c1ccc(O)cc1 InChI=1S/C19H22ClNO5/c1-12(19(25)14-3-5-15(22)6-4-14)21-9-8-13-2-7-17(16(20)10-13)26-11-18(23)24/h2-7,10,12,19,21-22,25H,8-9,11H2,1H3,(H,23,24)/t12-,19-/m1/s1 YNCNZXJRRRALAJ-CWTRNNRKSA-N 50122648 (alphaS,betaR)(2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid::CHEMBL13560 Beta-2 adrenergic receptor Canis familiaris 6457 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122648&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 11810992 104015288 CHEMBL13560 ZINC11422463 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833 51033070 C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 ZGGNJJJYUVRADP-ACJLOTCBSA-N 50002133 (+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid::(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid::(4-{2-[(R)-2-((R)-3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid::(4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid::(BRL 37,344)(4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid::(R*, R*) (4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid::2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid::BRL-37344::CHEMBL284782 Beta-2 adrenergic receptor Canis familiaris 9.1 ChEMBL 10.1021/jm020177z 10.7270/Q2BP03J1 12502364 Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Kissei Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002456&target=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002133&enzyme=Beta-2+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search 9841972 103916442 CHEMBL284782 567 ZINC03871771 1 MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL Beta-2 adrenergic receptor ADRB2_CANLF P54833