BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50630202 Cn1c(CN2C(=O)CSc3ccc(cc23)C(F)(F)F)nnc1SCc1ccc(Cl)cc1 InChI=1S/C20H16ClF3N4OS2/c1-27-17(25-26-19(27)31-10-12-2-5-14(21)6-3-12)9-28-15-8-13(20(22,23)24)4-7-16(15)30-11-18(28)29/h2-8H,9-11H2,1H3 XCSRSXRUZPDJHS-UHFFFAOYSA-N 50340014 4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one::CHEMBL1762483 Sodium/glucose cotransporter 1 Rattus norvegicus 9000 ChEMBL 10.1016/j.bmcl.2011.02.056 10.7270/Q25Q4WD2 21398124 Li, AR; Zhang, J; Greenberg, J; Lee, T; Liu, J Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50340014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50340014&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 2822337 131342950 CHEMBL1762483 ZINC01039775 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 50961620 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1OCc1ccccc1 InChI=1S/C26H32N2O7/c1-15(2)21-18(12-17-10-6-7-11-19(17)33-14-16-8-4-3-5-9-16)25(28-27-21)35-26-24(32)23(31)22(30)20(13-29)34-26/h3-11,15,20,22-24,26,29-32H,12-14H2,1-2H3,(H,27,28)/t20-,22-,23+,24-,26+/m1/s1 VKJYZOHVADWABC-TXKDOCKMSA-N 50394531 CHEMBL2159091 Sodium/glucose cotransporter 1 Rattus norvegicus 308 ChEMBL 10.1016/j.bmc.2012.09.037 10.7270/Q26D5V36 23062824 Fushimi, N; Fujikura, H; Shiohara, H; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Ozawa, T; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394531&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 9956975 163343555 CHEMBL2159091 C03400 ZINC95574988 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 50961621 OC[C@H]1O[C@@H](Oc2[nH]nc(c2Cc2ccccc2OCc2ccccc2)C(F)(F)F)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C24H25F3N2O7/c25-24(26,27)21-15(10-14-8-4-5-9-16(14)34-12-13-6-2-1-3-7-13)22(29-28-21)36-23-20(33)19(32)18(31)17(11-30)35-23/h1-9,17-20,23,30-33H,10-12H2,(H,28,29)/t17-,18-,19+,20-,23+/m1/s1 VRWBPJPUNCXWHA-MZSWFSNMSA-N 50394532 CHEMBL2159094 Sodium/glucose cotransporter 1 Rattus norvegicus 227 ChEMBL 10.1016/j.bmc.2012.09.037 10.7270/Q26D5V36 23062824 Fushimi, N; Fujikura, H; Shiohara, H; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Ozawa, T; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394532&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 10301121 163343556 CHEMBL2159094 C03400 ZINC95574341 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 50961622 OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1 IOUVKUPGCMBWBT-QNDFHXLGSA-N 20875 1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one::CHEMBL241384::CHEMBL245067::JMC511145 Compound 1::O-glucoside, 1::Phlorizin Sodium/glucose cotransporter 1 Rattus norvegicus 350 ChEMBL 10.1016/j.bmc.2012.09.037 10.7270/Q26D5V36 23062824 Fushimi, N; Fujikura, H; Shiohara, H; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Ozawa, T; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20875&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 6072 49688949 8113 CHEMBL241384CHEMBL245067 4757 C03400 ZINC03875408 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 50961628 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(O)cc1C InChI=1S/C20H28N2O7/c1-9(2)15-13(7-11-4-5-12(24)6-10(11)3)19(22-21-15)29-20-18(27)17(26)16(25)14(8-23)28-20/h4-6,9,14,16-18,20,23-27H,7-8H2,1-3H3,(H,21,22)/t14-,16-,17+,18-,20+/m1/s1 WVGZFGBLAOTZSN-NWDGLCLDSA-N 50394533 CHEMBL2159101 Sodium/glucose cotransporter 1 Rattus norvegicus 183 ChEMBL 10.1016/j.bmc.2012.09.037 10.7270/Q26D5V36 23062824 Fushimi, N; Fujikura, H; Shiohara, H; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Ozawa, T; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394533&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 10431578 163343557 CHEMBL2159101 C03400 ZINC38838483 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 50961629 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(C)cc1C InChI=1S/C21H30N2O6/c1-10(2)16-14(8-13-6-5-11(3)7-12(13)4)20(23-22-16)29-21-19(27)18(26)17(25)15(9-24)28-21/h5-7,10,15,17-19,21,24-27H,8-9H2,1-4H3,(H,22,23)/t15-,17-,18+,19-,21+/m1/s1 JDMDCYIKMZGDNP-UVPIGPOJSA-N 50394534 CHEMBL2159102 Sodium/glucose cotransporter 1 Rattus norvegicus 67 ChEMBL 10.1016/j.bmc.2012.09.037 10.7270/Q26D5V36 23062824 Fushimi, N; Fujikura, H; Shiohara, H; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Ozawa, T; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394534&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 71453232 163343558 CHEMBL2159102 C03400 ZINC95572048 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 51046121 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(CCCC(=O)NC(C)(C)C(=O)N2CCNCC2)cc1C InChI=1S/C32H49N5O8/c1-18(2)25-22(29(36-35-25)45-30-28(42)27(41)26(40)23(17-38)44-30)16-21-10-9-20(15-19(21)3)7-6-8-24(39)34-32(4,5)31(43)37-13-11-33-12-14-37/h9-10,15,18,23,26-28,30,33,38,40-42H,6-8,11-14,16-17H2,1-5H3,(H,34,39)(H,35,36)/t23-,26-,27+,28-,30+/m1/s1 HZIRWWOSGYBPSU-RHBSMATHSA-N 50426887 CHEMBL2323695 Sodium/glucose cotransporter 1 Rattus norvegicus 22 ChEMBL 10.1016/j.bmc.2012.11.041 10.7270/Q2445NS9 23273606 Fushimi, N; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Yamauchi, Y; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50426887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50426887&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 10009210 164155762 CHEMBL2323695 C03400 ZINC95582658 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 51046122 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(CCCC(=O)NC(C)(C)C(=O)N2CCNCC2)cc1 InChI=1S/C31H47N5O8/c1-18(2)24-21(28(35-34-24)44-29-27(41)26(40)25(39)22(17-37)43-29)16-20-10-8-19(9-11-20)6-5-7-23(38)33-31(3,4)30(42)36-14-12-32-13-15-36/h8-11,18,22,25-27,29,32,37,39-41H,5-7,12-17H2,1-4H3,(H,33,38)(H,34,35)/t22-,25+,26+,27-,29+/m1/s1 XLGGPHXVLBTVEQ-HUSNPGIHSA-N 50426888 CHEMBL2323694 Sodium/glucose cotransporter 1 Rattus norvegicus 104 ChEMBL 10.1016/j.bmc.2012.11.041 10.7270/Q2445NS9 23273606 Fushimi, N; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Yamauchi, Y; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50426888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50426888&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 11758523 164155763 CHEMBL2323694 C02900 ZINC03939543 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 51046123 CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(O)cc1C InChI=1S/C20H28N2O7/c1-9(2)15-13(7-11-4-5-12(24)6-10(11)3)19(22-21-15)29-20-18(27)17(26)16(25)14(8-23)28-20/h4-6,9,14,16-18,20,23-27H,7-8H2,1-3H3,(H,21,22)/t14-,16-,17+,18-,20+/m1/s1 WVGZFGBLAOTZSN-NWDGLCLDSA-N 50394533 CHEMBL2159101 Sodium/glucose cotransporter 1 Rattus norvegicus 183 ChEMBL 10.1016/j.bmc.2012.11.041 10.7270/Q2445NS9 23273606 Fushimi, N; Teranishi, H; Shimizu, K; Yonekubo, S; Ohno, K; Miyagi, T; Itoh, F; Shibazaki, T; Tomae, M; Ishikawa-Takemura, Y; Nakabayashi, T; Kamada, N; Yamauchi, Y; Kobayashi, S; Isaji, M Kissei Pharmaceutical Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394533&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 10431578 163343557 CHEMBL2159101 C03400 ZINC38838483 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787 51141167 COc1c2CCOc2c(Cc2ccc3OCCOc3c2)cc1[C@@H]1O[C@H](CO)[C@@H](F)[C@H](O)[C@H]1O InChI=1S/C24H27FO8/c1-29-23-14-4-5-32-22(14)13(8-12-2-3-16-17(9-12)31-7-6-30-16)10-15(23)24-21(28)20(27)19(25)18(11-26)33-24/h2-3,9-10,18-21,24,26-28H,4-8,11H2,1H3/t18-,19-,20+,21-,24+/m1/s1 QUHJWCHBJBZVQP-IDYLKPADSA-N 50467750 CHEMBL4279519 Sodium/glucose cotransporter 1 Rattus norvegicus 68 ChEMBL 10.1016/j.bmcl.2018.09.025 10.7270/Q2RB779G 30268701 Xu, G; Gaul, MD; Kuo, GH; Du, F; Xu, JZ; Wallace, N; Hinke, S; Kirchner, T; Silva, J; Huebert, ND; Lee, S; Murray, W; Liang, Y; Demarest, K Janssen Research & Development, L.L.C. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002408&target=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467750&enzyme=Sodium%2Fglucose+cotransporter+1&column=ki&startPg=0&Increment=50&submit=Search 137498470 433935015 1 MDSSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSFHIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLLTKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCGLDQDKGPKMTKEEEEAMKLKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA Sodium/glucose cotransporter 1 SC5A1_RAT P53790 P97787