BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50115079 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 Probable C-C chemokine receptor type 3 Mus musculus 20 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50115131 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 Probable C-C chemokine receptor type 3 Mus musculus 10 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50119530 [I-].CC[N+]1(C\C2=C\CCCCCC2)CC[C@@H](CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2.HI/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29;/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3;1H/b21-8+;/t24-,34?; FOAFBMYSXIGAOX-CJCAHDPRSA-N 50098624 1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::CHEMBL34626 Probable C-C chemokine receptor type 3 Mus musculus 350 ChEMBL 10.1021/jm0004244 10.7270/Q2G73D0G 11311066 Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098624&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918496 103995616 CHEMBL34626 ZINC13862637 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50127008 OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1 BKSRLDUBSLBPQQ-OFNKIYASSA-N 50161407 CHEMBL178447::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-hydroxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone Probable C-C chemokine receptor type 3 Mus musculus 606 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161407&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11466397 104047713 CHEMBL178447 ZINC28130372 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50141456 CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-16-33(19(3)35)12-10-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 ZFRLEPMXXGKKBN-WPFOTENUSA-N 50209974 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249854 Probable C-C chemokine receptor type 3 Mus musculus 7 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209974&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11953409 104086620 CHEMBL249854 ZINC28975388 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50141457 CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-16-33(19(3)35)12-10-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 ZFRLEPMXXGKKBN-WPFOTENUSA-N 50209974 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249854 Probable C-C chemokine receptor type 3 Mus musculus 3.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209974&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11953409 104086620 CHEMBL249854 ZINC28975388 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50141460 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 Probable C-C chemokine receptor type 3 Mus musculus 41 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50141461 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 Probable C-C chemokine receptor type 3 Mus musculus 54 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260573 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1cc(ccn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-11-15-34(16-12-20)14-3-17-38-24-7-4-22(31)5-8-24)25-9-6-23(32)19-27(25)35(26)28-18-21(30(36)37)10-13-33-28/h4-10,13,18-20H,2-3,11-12,14-17H2,1H3,(H,36,37) OVJKHLOCYYVIIT-UHFFFAOYSA-N 50041088 CHEMBL3355962 Probable C-C chemokine receptor type 3 Mus musculus 79 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041088&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721202 313067622 CHEMBL3355962 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260574 CCOC(=O)c1ccnc(c1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-13-17-36(18-14-22)16-5-19-40-26-9-6-24(33)7-10-26)27-11-8-25(34)21-29(27)37(28)30-20-23(12-15-35-30)32(38)39-4-2/h6-12,15,20-22H,3-5,13-14,16-19H2,1-2H3 VJUTWTGDFJIQRL-UHFFFAOYSA-N 50041089 CHEMBL3355963 Probable C-C chemokine receptor type 3 Mus musculus 110 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041089&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721203 313067623 CHEMBL3355963 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260575 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)[nH]c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 50041090 CHEMBL3355964 Probable C-C chemokine receptor type 3 Mus musculus 64 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041090&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721204 313067624 CHEMBL3355964 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260576 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)n(-c2ccc(cn2)C(O)=O)c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C34H38Cl2FN5O3/c1-3-29-32(26-8-7-24(37)19-30(26)42(29)31-10-6-23(20-39-31)33(43)44)22-11-14-41(15-12-22)16-13-25(40-34(45)38-4-2)17-21-5-9-27(35)28(36)18-21/h5-10,18-20,22,25H,3-4,11-17H2,1-2H3,(H,43,44)(H2,38,40,45)/t25-/m0/s1 CRQFSPXWIUARST-VWLOTQADSA-N 50041091 CHEMBL3355965 Probable C-C chemokine receptor type 3 Mus musculus 270 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041091&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721205 313067625 CHEMBL3355965 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260577 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)n(-c2ccc(cn2)C(=O)OC)c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C35H40Cl2FN5O3/c1-4-30-33(27-9-8-25(38)20-31(27)43(30)32-11-7-24(21-40-32)34(44)46-3)23-12-15-42(16-13-23)17-14-26(41-35(45)39-5-2)18-22-6-10-28(36)29(37)19-22/h6-11,19-21,23,26H,4-5,12-18H2,1-3H3,(H2,39,41,45)/t26-/m0/s1 LGOIHCUQXWJJQO-SANMLTNESA-N 50041092 CHEMBL3355966 Probable C-C chemokine receptor type 3 Mus musculus 660 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041092&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721206 313067626 CHEMBL3355966 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260633 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H28F2N2S/c1-2-22-24(21-9-6-19(26)16-23(21)27-22)17-10-13-28(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,27H,2-3,10-15H2,1H3 HUEVBCXRDKKBRQ-UHFFFAOYSA-N 50041150 CHEMBL3355932 Probable C-C chemokine receptor type 3 Mus musculus 10.0 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041150&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57718837 103972994 CHEMBL3355932 ZINC36215428 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260634 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccccc2)CC1 InChI=1S/C24H29FN2S/c1-2-22-24(21-10-9-19(25)17-23(21)26-22)18-11-14-27(15-12-18)13-6-16-28-20-7-4-3-5-8-20/h3-5,7-10,17-18,26H,2,6,11-16H2,1H3 JBXDGESFQNPBFT-UHFFFAOYSA-N 50041157 CHEMBL3355933 Probable C-C chemokine receptor type 3 Mus musculus 65 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041157&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721184 312697463 CHEMBL3355933 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260635 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(C)cc2)CC1 InChI=1S/C25H31FN2S/c1-3-23-25(22-10-7-20(26)17-24(22)27-23)19-11-14-28(15-12-19)13-4-16-29-21-8-5-18(2)6-9-21/h5-10,17,19,27H,3-4,11-16H2,1-2H3 PEHVIDOBHKJWSJ-UHFFFAOYSA-N 50041158 CHEMBL3355934 Probable C-C chemokine receptor type 3 Mus musculus 62 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041158&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721185 313067627 CHEMBL3355934 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260636 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(O)cc2)CC1 InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-4-18(25)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-5-19(28)6-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3 QULTXLKAKCQMRD-UHFFFAOYSA-N 50041163 CHEMBL3355935 Probable C-C chemokine receptor type 3 Mus musculus 210 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041163&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721186 313067628 CHEMBL3355935 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260637 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(OC)cc2)CC1 InChI=1S/C25H31FN2OS/c1-3-23-25(22-10-5-19(26)17-24(22)27-23)18-11-14-28(15-12-18)13-4-16-30-21-8-6-20(29-2)7-9-21/h5-10,17-18,27H,3-4,11-16H2,1-2H3 VGSYCJKOMDSIPP-UHFFFAOYSA-N 50041166 CHEMBL3355936 Probable C-C chemokine receptor type 3 Mus musculus 130 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041166&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721187 313067629 CHEMBL3355936 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260638 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(cc2)C(N)=O)CC1 InChI=1S/C25H30FN3OS/c1-2-22-24(21-9-6-19(26)16-23(21)28-22)17-10-13-29(14-11-17)12-3-15-31-20-7-4-18(5-8-20)25(27)30/h4-9,16-17,28H,2-3,10-15H2,1H3,(H2,27,30) CRBGNOGVLJKUSQ-UHFFFAOYSA-N 50041167 CHEMBL3355937 Probable C-C chemokine receptor type 3 Mus musculus 1300 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041167&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721188 313067630 CHEMBL3355937 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260639 Cc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H26F2N2S/c1-16-23(21-8-5-19(25)15-22(21)26-16)17-9-12-27(13-10-17)11-2-14-28-20-6-3-18(24)4-7-20/h3-8,15,17,26H,2,9-14H2,1H3 OVVLDNUJGJJFNW-UHFFFAOYSA-N 50041174 CHEMBL3355938 Probable C-C chemokine receptor type 3 Mus musculus 37 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041174&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721189 313067631 CHEMBL3355938 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260640 OCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H26F2N2OS/c24-17-2-5-19(6-3-17)29-13-1-10-27-11-8-16(9-12-27)23-20-7-4-18(25)14-21(20)26-22(23)15-28/h2-7,14,16,26,28H,1,8-13,15H2 DTLONXZATYJNCF-UHFFFAOYSA-N 50041181 CHEMBL3355939 Probable C-C chemokine receptor type 3 Mus musculus 18 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041181&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721190 313067632 CHEMBL3355939 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260641 COC(C)c1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 50041182 CHEMBL3355940 Probable C-C chemokine receptor type 3 Mus musculus 52 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041182&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721191 313067633 CHEMBL3355940 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260642 CCc1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H29FN2S/c1-2-22-24(21-6-3-4-7-23(21)26-22)18-12-15-27(16-13-18)14-5-17-28-20-10-8-19(25)9-11-20/h3-4,6-11,18,26H,2,5,12-17H2,1H3 NMYOEGLWLBKTCW-UHFFFAOYSA-N 50041203 CHEMBL3355942 Probable C-C chemokine receptor type 3 Mus musculus 400 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041203&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66906657 313067653 CHEMBL3355942 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260643 OCc1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H27FN2OS/c24-18-6-8-19(9-7-18)28-15-3-12-26-13-10-17(11-14-26)23-20-4-1-2-5-21(20)25-22(23)16-27/h1-2,4-9,17,25,27H,3,10-16H2 IVMJBDLZRRUJCW-UHFFFAOYSA-N 50041184 CHEMBL3355943 Probable C-C chemokine receptor type 3 Mus musculus 92 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041184&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721193 313067635 CHEMBL3355943 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260644 COC(C)c1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 50041185 CHEMBL3355944 Probable C-C chemokine receptor type 3 Mus musculus 24 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041185&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721194 313067636 CHEMBL3355944 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260645 CCc1[nH]c2cc(C)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C25H31FN2S/c1-3-23-25(22-10-5-18(2)17-24(22)27-23)19-11-14-28(15-12-19)13-4-16-29-21-8-6-20(26)7-9-21/h5-10,17,19,27H,3-4,11-16H2,1-2H3 TVSACSZJCZUBIY-UHFFFAOYSA-N 50041186 CHEMBL3355945 Probable C-C chemokine receptor type 3 Mus musculus 48 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041186&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721195 312697464 CHEMBL3355945 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260646 CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3 RUBACXIFRPVRKI-UHFFFAOYSA-N 50041187 CHEMBL3355946 Probable C-C chemokine receptor type 3 Mus musculus 370 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041187&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721196 313067637 CHEMBL3355946 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260660 CCc1[nH]c2cc(ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1)C(N)=O InChI=1S/C25H30FN3OS/c1-2-22-24(21-9-4-18(25(27)30)16-23(21)28-22)17-10-13-29(14-11-17)12-3-15-31-20-7-5-19(26)6-8-20/h4-9,16-17,28H,2-3,10-15H2,1H3,(H2,27,30) HACDQWKCIZHKJO-UHFFFAOYSA-N 50041200 CHEMBL3355948 Probable C-C chemokine receptor type 3 Mus musculus 380 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041200&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721198 313067650 CHEMBL3355948 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260661 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1C InChI=1S/C25H30F2N2S/c1-3-23-25(22-10-7-20(27)17-24(22)28(23)2)18-11-14-29(15-12-18)13-4-16-30-21-8-5-19(26)6-9-21/h5-10,17-18H,3-4,11-16H2,1-2H3 CSRQGGQDNMNQEX-UHFFFAOYSA-N 50041201 CHEMBL3355950 Probable C-C chemokine receptor type 3 Mus musculus 85 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041201&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57718829 313067651 CHEMBL3355950 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260662 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccccc1 InChI=1S/C30H32F2N2S/c1-2-28-30(27-14-11-24(32)21-29(27)34(28)25-7-4-3-5-8-25)22-15-18-33(19-16-22)17-6-20-35-26-12-9-23(31)10-13-26/h3-5,7-14,21-22H,2,6,15-20H2,1H3 YWGYONXMCGHURW-UHFFFAOYSA-N 50041190 CHEMBL3355951 Probable C-C chemokine receptor type 3 Mus musculus 650 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041190&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952524 313067640 CHEMBL3355951 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260663 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1CC(O)=O InChI=1S/C26H30F2N2O2S/c1-2-23-26(22-9-6-20(28)16-24(22)30(23)17-25(31)32)18-10-13-29(14-11-18)12-3-15-33-21-7-4-19(27)5-8-21/h4-9,16,18H,2-3,10-15,17H2,1H3,(H,31,32) MPXYNWUUGMMVRW-UHFFFAOYSA-N 50041191 CHEMBL3355952 Probable C-C chemokine receptor type 3 Mus musculus 74 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041191&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24937215 313067641 CHEMBL3355952 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260664 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cc1)C(O)=O InChI=1S/C31H32F2N2O2S/c1-2-28-30(21-14-17-34(18-15-21)16-3-19-38-26-11-6-23(32)7-12-26)27-13-8-24(33)20-29(27)35(28)25-9-4-22(5-10-25)31(36)37/h4-13,20-21H,2-3,14-19H2,1H3,(H,36,37) QXCXDQFFJYBNTP-UHFFFAOYSA-N 50041192 CHEMBL3355953 Probable C-C chemokine receptor type 3 Mus musculus 120 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041192&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952526 313067642 CHEMBL3355953 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260665 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cc1)-c1nnn[nH]1 InChI=1S/C31H32F2N6S/c1-2-28-30(21-14-17-38(18-15-21)16-3-19-40-26-11-6-23(32)7-12-26)27-13-8-24(33)20-29(27)39(28)25-9-4-22(5-10-25)31-34-36-37-35-31/h4-13,20-21H,2-3,14-19H2,1H3,(H,34,35,36,37) QTAMIHYZGWVETD-UHFFFAOYSA-N 50041193 CHEMBL3355954 Probable C-C chemokine receptor type 3 Mus musculus 72 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041193&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721200 313067643 CHEMBL3355954 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260666 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-12-15-34(16-13-20)14-3-17-38-24-8-5-22(31)6-9-24)25-10-7-23(32)18-27(25)35(26)28-11-4-21(19-33-28)30(36)37/h4-11,18-20H,2-3,12-17H2,1H3,(H,36,37) YUCBOQQXHCEAOT-UHFFFAOYSA-N 50041195 CHEMBL3355956 Probable C-C chemokine receptor type 3 Mus musculus 630 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041195&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024651 313067645 CHEMBL3355956 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260667 CCOC(=O)Cn1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C28H34F2N2O2S/c1-3-25-28(24-11-8-22(30)18-26(24)32(25)19-27(33)34-4-2)20-12-15-31(16-13-20)14-5-17-35-23-9-6-21(29)7-10-23/h6-11,18,20H,3-5,12-17,19H2,1-2H3 MAFSPAYMPQWVRE-UHFFFAOYSA-N 50041202 CHEMBL3355957 Probable C-C chemokine receptor type 3 Mus musculus 230 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041202&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24937092 313067652 CHEMBL3355957 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260668 CCOC(=O)c1ccc(cc1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C33H36F2N2O2S/c1-3-30-32(23-16-19-36(20-17-23)18-5-21-40-28-13-8-25(34)9-14-28)29-15-10-26(35)22-31(29)37(30)27-11-6-24(7-12-27)33(38)39-4-2/h6-15,22-23H,3-5,16-21H2,1-2H3 JRCSAKBNGXSAGM-UHFFFAOYSA-N 50041196 CHEMBL3355958 Probable C-C chemokine receptor type 3 Mus musculus 2600 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041196&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952525 313067646 CHEMBL3355958 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260669 CCOC(=O)c1ccc(nc1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-14-17-36(18-15-22)16-5-19-40-26-10-7-24(33)8-11-26)27-12-9-25(34)20-29(27)37(28)30-13-6-23(21-35-30)32(38)39-4-2/h6-13,20-22H,3-5,14-19H2,1-2H3 WCDMZYLZUNFULY-UHFFFAOYSA-N 50041197 CHEMBL3355959 Probable C-C chemokine receptor type 3 Mus musculus 740 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041197&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024849 313067647 CHEMBL3355959 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260670 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1cccc(n1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-13-16-34(17-14-20)15-4-18-38-23-10-7-21(31)8-11-23)24-12-9-22(32)19-27(24)35(26)28-6-3-5-25(33-28)30(36)37/h3,5-12,19-20H,2,4,13-18H2,1H3,(H,36,37) RKONWZSIRONAFM-UHFFFAOYSA-N 50041198 CHEMBL3355960 Probable C-C chemokine receptor type 3 Mus musculus 110 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041198&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024650 313067648 CHEMBL3355960 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50260671 CCOC(=O)c1cccc(n1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-15-18-36(19-16-22)17-6-20-40-25-12-9-23(33)10-13-25)26-14-11-24(34)21-29(26)37(28)30-8-5-7-27(35-30)32(38)39-4-2/h5,7-14,21-22H,3-4,6,15-20H2,1-2H3 MFNWFHKBFKEKAN-UHFFFAOYSA-N 50041199 CHEMBL3355961 Probable C-C chemokine receptor type 3 Mus musculus 410 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041199&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024850 313067649 CHEMBL3355961 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50515428 [O-][n+]1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccc3cc(F)ccc3c2)c(c1)C(=O)N1CCCCC1 InChI=1S/C30H33FN4O3/c31-23-7-6-21-14-20(4-5-22(21)15-23)18-35-25-8-9-26(35)17-24(16-25)32-29(36)27-10-13-34(38)19-28(27)30(37)33-11-2-1-3-12-33/h4-7,10,13-15,19,24-26H,1-3,8-9,11-12,16-18H2,(H,32,36)/t25-,26-/m1/s1 SBJLPUIBYIEHFY-CLJLJLNGSA-N 50264212 CHEMBL519042::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)isonicotinamide 1-oxide Probable C-C chemokine receptor type 3 Mus musculus 1100 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264212&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579713 104112290 CHEMBL519042 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50515431 Oc1ccccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H30FN3O3/c30-24-8-7-22-15-21(5-6-23(22)17-24)18-32-12-11-25(19-32)31-28(35)16-20-9-13-33(14-10-20)29(36)26-3-1-2-4-27(26)34/h1-8,15-17,25,34H,9-14,18-19H2,(H,31,35)/t25-/m1/s1 TVBOHVNCFNQWSW-RUZDIDTESA-N 50297171 CHEMBL551735::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxybenzoyl)piperidin-4-ylidene]acetamide Probable C-C chemokine receptor type 3 Mus musculus 230 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297171&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44512617 104138702 CHEMBL551735 ZINC43024685 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50857914 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 Probable C-C chemokine receptor type 3 Mus musculus 31 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 51001171 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 Probable C-C chemokine receptor type 3 Mus musculus 41 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7 50998203 [I-].CC[N+]1(C\C2=C\CCCCCC2)CC[C@@H](CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2.HI/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29;/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3;1H/b21-8+;/t24-,34?; FOAFBMYSXIGAOX-CJCAHDPRSA-N 50098624 1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::CHEMBL34626 Probable C-C chemokine receptor type 3 Mus musculus 460 ChEMBL 10.1021/jm0004244 10.7270/Q2G73D0G 11311066 Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50002102&target=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098624&enzyme=Probable+C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918496 103995616 CHEMBL34626 ZINC13862637 1 MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF Probable C-C chemokine receptor type 3 CCR3_MOUSE P51678 Q8K3M7