BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50420710 CCc1nnc(-c2ccc(nc2)-c2ccccc2)n1-c1cccc(C#N)c1C InChI=1S/C23H19N5/c1-3-22-26-27-23(28(22)21-11-7-10-18(14-24)16(21)2)19-12-13-20(25-15-19)17-8-5-4-6-9-17/h4-13,15H,3H2,1-2H3 DAAWESBJYLHFAS-UHFFFAOYSA-N 50439754 CHEMBL2419440 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >30000 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439754&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 9925334 175452071 CHEMBL2419440 ZINC34030881 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708268 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc2ncccc12 InChI=1S/C25H20N4/c1-2-24-27-28-25(20-15-13-19(14-16-20)18-8-4-3-5-9-18)29(24)23-12-6-11-22-21(23)10-7-17-26-22/h3-17H,2H2,1H3 AUSOMKIODUFZMD-UHFFFAOYSA-N 50360091 CHEMBL1928738 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2700 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360091&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 57391966 136964153 CHEMBL1928738 ZINC82154640 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708280 CC(C)c1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C23H20FN3/c1-16(2)22-25-26-23(27(22)21-11-7-6-10-20(21)24)19-14-12-18(13-15-19)17-8-4-3-5-9-17/h3-16H,1-2H3 XOGABADGFOGOCV-UHFFFAOYSA-N 50335011 3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-1,2,4-triazole::CHEMBL1649975 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 3300 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335011&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 22019234 125085113 CHEMBL1649975 ZINC01910267 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708281 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C22H18FN3/c1-2-21-24-25-22(26(21)20-11-7-6-10-19(20)23)18-14-12-17(13-15-18)16-8-4-3-5-9-16/h3-15H,2H2,1H3 ZQUPMAQZJIGBHA-UHFFFAOYSA-N 50335010 3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-triazole::CHEMBL1649974 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 230 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335010&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50993656 125085112 CHEMBL1649974 ZINC66101607 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708282 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc2cccnc12 InChI=1S/C25H20N4/c1-2-23-27-28-25(21-15-13-19(14-16-21)18-8-4-3-5-9-18)29(23)22-12-6-10-20-11-7-17-26-24(20)22/h3-17H,2H2,1H3 STQBPEFFVPAJNJ-UHFFFAOYSA-N 50360102 CHEMBL1928735 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 380 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360102&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 57395412 136964164 CHEMBL1928735 ZINC82153718 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708283 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc2ccncc12 InChI=1S/C25H20N4/c1-2-24-27-28-25(21-13-11-19(12-14-21)18-7-4-3-5-8-18)29(24)23-10-6-9-20-15-16-26-17-22(20)23/h3-17H,2H2,1H3 LDUDYGIBRRIZAY-UHFFFAOYSA-N 50360092 CHEMBL1928736 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 4200 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360092&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 57391965 136964154 CHEMBL1928736 ZINC82153719 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50708284 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc2cnccc12 InChI=1S/C25H20N4/c1-2-24-27-28-25(20-13-11-19(12-14-20)18-7-4-3-5-8-18)29(24)23-10-6-9-21-17-26-16-15-22(21)23/h3-17H,2H2,1H3 WNFUGBCAFJJYPS-UHFFFAOYSA-N 50360093 CHEMBL1928737 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 14000 ChEMBL 10.1016/j.bmc.2011.11.038 10.7270/Q2WM1DVF 22177408 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Morita, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360093&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 22019226 136964155 CHEMBL1928737 ZINC82154637 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732455 CC(C)c1cccc(c1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C20H21F2NO2/c1-12(2)13-4-3-5-14(10-13)16(8-9-19(23)20(24)25)17-7-6-15(21)11-18(17)22/h3-8,10-12,19H,9,23H2,1-2H3,(H,24,25)/p-1/b16-8+ NKJVHBUEZJVPSI-LZYBPNLTSA-M 50099861 CHEMBL28549::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(3-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1590 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099861&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931651 103996686 CHEMBL28549 ZINC28769246 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732456 Cc1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C18H17F2NO2/c1-11-2-4-12(5-3-11)14(8-9-17(21)18(22)23)15-7-6-13(19)10-16(15)20/h2-8,10,17H,9,21H2,1H3,(H,22,23)/p-1/b14-8+ NNAYBLKMRJOMDE-RIYZIHGNSA-M 50099863 CHEMBL29023::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-p-tolyl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1170 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099863&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931652 103996688 CHEMBL29023 ZINC28768576 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732457 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C20H21F2NO2/c1-12(2)13-3-5-14(6-4-13)16(9-10-19(23)20(24)25)17-8-7-15(21)11-18(17)22/h3-9,11-12,19H,10,23H2,1-2H3,(H,24,25)/p-1/b16-9+ ODWZNBOTFNAHQY-CXUHLZMHSA-M 50099862 CHEMBL28746::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 330 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099862&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 21158950 103996687 CHEMBL28746 ZINC28769531 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732458 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccccc1F InChI=1S/C20H22FNO2/c1-13(2)14-7-9-15(10-8-14)16(11-12-19(22)20(23)24)17-5-3-4-6-18(17)21/h3-11,13,19H,12,22H2,1-2H3,(H,23,24)/p-1/b16-11+ AATKXXQGCCDEFN-LFIBNONCSA-M 50099859 CHEMBL29220::Sodium; (E)-2-amino-5-(2-fluoro-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 290 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099859&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 21158952 103996684 CHEMBL29220 ZINC28769770 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732460 CCc1ccc(cc1CC)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C21H23F2NO2/c1-3-13-5-6-15(11-14(13)4-2)17(9-10-20(24)21(25)26)18-8-7-16(22)12-19(18)23/h5-9,11-12,20H,3-4,10,24H2,1-2H3,(H,25,26)/p-1/b17-9+ WNTAPKFMXVBWHD-RQZCQDPDSA-M 50099866 CHEMBL418388::Sodium; (E)-2-amino-5-(3,4-diethyl-phenyl)-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 660 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099866&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931654 103996691 CHEMBL418388 ZINC28768833 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732462 CC(C)c1ccc(cc1)C(=CCC(N)C([O-])=O)c1ccc(cc1)C(C)C InChI=1S/C23H29NO2/c1-15(2)17-5-9-19(10-6-17)21(13-14-22(24)23(25)26)20-11-7-18(8-12-20)16(3)4/h5-13,15-16,22H,14,24H2,1-4H3,(H,25,26)/p-1 QANDPCXAFPDYIN-UHFFFAOYSA-M 50099865 CHEMBL283017::Sodium; 2-amino-5,5-bis-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2030 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099865&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931653 103996690 CHEMBL283017 ZINC28770748 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732463 CC(C)c1ccc(cc1)C(=C\CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C20H21F2NO2/c1-12(2)13-3-5-14(6-4-13)16(9-10-19(23)20(24)25)17-8-7-15(21)11-18(17)22/h3-9,11-12,19H,10,23H2,1-2H3,(H,24,25)/p-1/b16-9- ODWZNBOTFNAHQY-SXGWCWSVSA-M 50099860 CHEMBL416203::Sodium; (Z)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099860&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 18691455 103996685 CHEMBL416203 ZINC28769009 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732470 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(cc1)C#N InChI=1S/C21H22N2O2/c1-14(2)16-7-9-18(10-8-16)19(11-12-20(23)21(24)25)17-5-3-15(13-22)4-6-17/h3-11,14,20H,12,23H2,1-2H3,(H,24,25)/p-1/b19-11- ANMOQNABXYRCIW-ODLFYWEKSA-M 50099872 CHEMBL285592::Sodium; (E)-2-amino-5-(4-cyano-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2640 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099872&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931659 103996697 CHEMBL285592 ZINC28769948 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732472 COc1ccc(cc1)C(=C\CC(N)C([O-])=O)\c1ccc(cc1)C(C)C InChI=1S/C21H25NO3/c1-14(2)15-4-6-16(7-5-15)19(12-13-20(22)21(23)24)17-8-10-18(25-3)11-9-17/h4-12,14,20H,13,22H2,1-3H3,(H,23,24)/p-1/b19-12+ GLTAJJQDSPPOGH-XDHOZWIPSA-M 50099873 CHEMBL29964::Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-(4-methoxy-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1160 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099873&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931660 103996698 CHEMBL29964 ZINC28769042 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732475 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccsc1 InChI=1S/C18H21NO2S/c1-12(2)13-3-5-14(6-4-13)16(15-9-10-22-11-15)7-8-17(19)18(20)21/h3-7,9-12,17H,8,19H2,1-2H3,(H,20,21)/p-1/b16-7+ LMXWPUHEXUOSBI-FRKPEAEDSA-M 50099858 CHEMBL285370::Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-thiophen-3-yl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1030 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099858&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931650 103996683 CHEMBL285370 ZINC28769233 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732476 NC(C\C=C(/c1ccc(cc1)C#N)c1ccc(F)cc1F)C([O-])=O InChI=1S/C18H14F2N2O2/c19-13-5-6-15(16(20)9-13)14(7-8-17(22)18(23)24)12-3-1-11(10-21)2-4-12/h1-7,9,17H,8,22H2,(H,23,24)/p-1/b14-7+ KEAJHTZYSWBADO-VGOFMYFVSA-M 50099876 CHEMBL287626::Sodium; (E)-2-amino-5-(4-cyano-phenyl)-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099876&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931662 103996701 CHEMBL287626 ZINC28769515 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732477 CC(C)c1ccc(cc1)C(=C/C[C@H](N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C20H21F2NO2/c1-12(2)13-3-5-14(6-4-13)16(9-10-19(23)20(24)25)17-8-7-15(21)11-18(17)22/h3-9,11-12,19H,10,23H2,1-2H3,(H,24,25)/p-1/b16-9+/t19-/m0/s1 ODWZNBOTFNAHQY-HVRVZBDQSA-M 50099875 (E)-2-Amino-5-(2,4-difluoro-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoic acid anion; sodium::CHEMBL28578 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 150 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099875&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931661 103996700 CHEMBL28578 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732478 N[C@@H](C\C=C(/c1ccc2ccccc2c1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C21H17F2NO2/c22-16-7-8-18(19(23)12-16)17(9-10-20(24)21(25)26)15-6-5-13-3-1-2-4-14(13)11-15/h1-9,11-12,20H,10,24H2,(H,25,26)/p-1/b17-9+/t20-/m0/s1 DLLMZUUUVDJRNI-ZUNINTSYSA-M 50099878 (E)-2-Amino-5-(2,4-difluoro-phenyl)-5-naphthalen-2-yl-pent-4-enoic acid anion; sodium::CHEMBL30144 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 365 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099878&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931664 103996703 CHEMBL30144 ZINC28768596 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732479 CCc1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C19H19F2NO2/c1-2-12-3-5-13(6-4-12)15(9-10-18(22)19(23)24)16-8-7-14(20)11-17(16)21/h3-9,11,18H,2,10,22H2,1H3,(H,23,24)/p-1/b15-9+ FYWPLKCPFADHMJ-OQLLNIDSSA-M 50099879 CHEMBL28601::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-ethyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 460 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099879&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931665 103996704 CHEMBL28601 ZINC28768436 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732480 NC(C\C=C(/c1ccc(cc1)-c1ccccc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C23H19F2NO2/c24-18-10-11-20(21(25)14-18)19(12-13-22(26)23(27)28)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-12,14,22H,13,26H2,(H,27,28)/p-1/b19-12+ KMPYCKYISJFXDN-XDHOZWIPSA-M 50099877 CHEMBL29396::Sodium; (E)-2-amino-5-biphenyl-4-yl-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 3660 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099877&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931663 103996702 CHEMBL29396 ZINC28768582 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732481 COc1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C18H17F2NO3/c1-24-13-5-2-11(3-6-13)14(8-9-17(21)18(22)23)15-7-4-12(19)10-16(15)20/h2-8,10,17H,9,21H2,1H3,(H,22,23)/p-1/b14-8+ TUTSBHOFVXDEBG-RIYZIHGNSA-M 50099880 CHEMBL29279::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-methoxy-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2030 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099880&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931666 103996705 CHEMBL29279 ZINC28769311 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732484 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(cc1)C(C)(C)C InChI=1S/C24H31NO2/c1-16(2)17-6-8-18(9-7-17)21(14-15-22(25)23(26)27)19-10-12-20(13-11-19)24(3,4)5/h6-14,16,22H,15,25H2,1-5H3,(H,26,27)/p-1/b21-14+ SBHYREVKOXXNLS-KGENOOAVSA-M 50099871 CHEMBL286706::Sodium; (E)-2-amino-5-(4-tert-butyl-phenyl)-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 5470 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099871&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931658 103996696 CHEMBL286706 ZINC28769767 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732486 NC(C\C=C(/c1ccsc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C15H13F2NO2S/c16-10-1-2-12(13(17)7-10)11(9-5-6-21-8-9)3-4-14(18)15(19)20/h1-3,5-8,14H,4,18H2,(H,19,20)/p-1/b11-3+ HZJDVLYSPPQMTL-QDEBKDIKSA-M 50099874 CHEMBL28016::Sodium; (Z)-2-amino-5-(2,4-difluoro-phenyl)-5-thiophen-3-yl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 5880 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099874&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 18691441 103996699 CHEMBL28016 ZINC28770283 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732488 CC(C)(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C21H23F2NO2/c1-21(2,3)14-6-4-13(5-7-14)16(10-11-19(24)20(25)26)17-9-8-15(22)12-18(17)23/h4-10,12,19H,11,24H2,1-3H3,(H,25,26)/p-1/b16-10+ WYCLXMAZRDIHSB-MHWRWJLKSA-M 50099881 (E)-2-Amino-5-(4-tert-butyl-phenyl)-5-(2,4-difluoro-phenyl)-pent-4-enoic acid anion::CHEMBL283230 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1740 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099881&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931667 103996706 CHEMBL283230 ZINC28771744 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732489 NC(C\C=C(\c1ccc(cc1)-c1ccccc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C23H19F2NO2/c24-18-10-11-20(21(25)14-18)19(12-13-22(26)23(27)28)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-12,14,22H,13,26H2,(H,27,28)/p-1/b19-12- KMPYCKYISJFXDN-UNOMPAQXSA-M 50099864 CHEMBL27850::Sodium; (Z)-2-amino-5-biphenyl-4-yl-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2400 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099864&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 18691445 103996689 CHEMBL27850 ZINC28768975 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732490 NC(C\C=C(/c1cccc(c1)-c1ccccc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C23H19F2NO2/c24-18-9-10-20(21(25)14-18)19(11-12-22(26)23(27)28)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-11,13-14,22H,12,26H2,(H,27,28)/p-1/b19-11+ QNDJXJVELANHNI-YBFXNURJSA-M 50099868 CHEMBL27914::Sodium; (E)-2-amino-5-biphenyl-3-yl-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1340 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099868&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931656 103996693 CHEMBL27914 ZINC28769200 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732493 NC(C\C=C(/c1ccc2ccccc2c1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C21H17F2NO2/c22-16-7-8-18(19(23)12-16)17(9-10-20(24)21(25)26)15-6-5-13-3-1-2-4-14(13)11-15/h1-9,11-12,20H,10,24H2,(H,25,26)/p-1/b17-9+ DLLMZUUUVDJRNI-RQZCQDPDSA-M 50099883 CHEMBL28577::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-naphthalen-2-yl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 770 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099883&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931668 103996708 CHEMBL28577 ZINC28768598 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732498 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1cccnc1 InChI=1S/C19H22N2O2/c1-13(2)14-5-7-15(8-6-14)17(9-10-18(20)19(22)23)16-4-3-11-21-12-16/h3-9,11-13,18H,10,20H2,1-2H3,(H,22,23)/p-1/b17-9+ RBQHMQONLZLENY-RQZCQDPDSA-M 50099867 CHEMBL28570::Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-pyridin-3-yl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 5930 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099867&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931655 103996692 CHEMBL28570 ZINC28770274 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732499 NC(C\C=C(\c1ccc(F)cc1F)c1ccccc1-c1ccccc1)C([O-])=O InChI=1S/C23H19F2NO2/c24-16-10-11-20(21(25)14-16)19(12-13-22(26)23(27)28)18-9-5-4-8-17(18)15-6-2-1-3-7-15/h1-12,14,22H,13,26H2,(H,27,28)/p-1/b19-12+ MELCIKNELJLXGI-XDHOZWIPSA-M 50099870 CHEMBL29022::Sodium; (E)-2-amino-5-biphenyl-2-yl-5-(2,4-difluoro-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2750 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099870&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931657 103996695 CHEMBL29022 ZINC28768573 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732500 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccccc1 InChI=1S/C20H23NO2/c1-14(2)15-8-10-17(11-9-15)18(12-13-19(21)20(22)23)16-6-4-3-5-7-16/h3-12,14,19H,13,21H2,1-2H3,(H,22,23)/p-1/b18-12- NEFATTVTHZVHRQ-PDGQHHTCSA-M 50099882 CHEMBL29958::Sodium; (Z)-2-amino-5-(4-isopropyl-phenyl)-5-phenyl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 400 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099882&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 21158951 103996707 CHEMBL29958 ZINC28768761 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732502 NC(C\C=C(/c1cccnc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C16H14F2N2O2/c17-11-3-4-13(14(18)8-11)12(5-6-15(19)16(21)22)10-2-1-7-20-9-10/h1-5,7-9,15H,6,19H2,(H,21,22)/p-1/b12-5+ PXVJIHAGSDTPSO-LFYBBSHMSA-M 50099869 (E)-2-Amino-5-(2,4-difluoro-phenyl)-5-pyridin-3-yl-pent-4-enoic acid anion Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099869&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 44278313 103996694 29067 ZINC28770280 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732504 CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1ccc(cc1)-c1ccccc1 InChI=1S/C26H27NO2/c1-18(2)19-8-12-22(13-9-19)24(16-17-25(27)26(28)29)23-14-10-21(11-15-23)20-6-4-3-5-7-20/h3-16,18,25H,17,27H2,1-2H3,(H,28,29)/p-1/b24-16+ VVOBHTHCFTVAFI-LFVJCYFKSA-M 50099885 CHEMBL281450::Sodium; (E)-2-amino-5-biphenyl-4-yl-5-(4-isopropyl-phenyl)-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 2060 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099885&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931670 103996710 CHEMBL281450 ZINC28769038 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732505 CCc1ccc(cc1CC)C(=C/C[C@H](N)C([O-])=O)\c1ccc(F)cc1F InChI=1S/C21H23F2NO2/c1-3-13-5-6-15(11-14(13)4-2)17(9-10-20(24)21(25)26)18-8-7-16(22)12-19(18)23/h5-9,11-12,20H,3-4,10,24H2,1-2H3,(H,25,26)/p-1/b17-9+/t20-/m0/s1 WNTAPKFMXVBWHD-ZUNINTSYSA-M 50099886 (E)-2-Amino-5-(3,4-diethyl-phenyl)-5-(2,4-difluoro-phenyl)-pent-4-enoic acid anion; sodium::CHEMBL29608 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 283 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099886&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931671 103996711 CHEMBL29608 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50732506 NC(C\C=C(/c1ccccc1)c1ccc(F)cc1F)C([O-])=O InChI=1S/C17H15F2NO2/c18-12-6-7-14(15(19)10-12)13(8-9-16(20)17(21)22)11-4-2-1-3-5-11/h1-8,10,16H,9,20H2,(H,21,22)/p-1/b13-8+ UXZIIQFJOJRUEL-MDWZMJQESA-M 50099884 CHEMBL29256::Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-phenyl-pent-4-enoate Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 6440 ChEMBL 10.1016/s0960-894x(01)00253-0 10.7270/Q20C4W9Q 11378357 Isaac, M; Slassi, A; Silva, KD; Arora, J; MacLean, N; Hung, B; McCallum, K NPS Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099884&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 91931669 103996709 CHEMBL29256 ZINC28768604 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919793 CNc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H17FN4/c1-23-21-25-24-20(26(21)19-10-6-5-9-18(19)22)17-13-11-16(12-14-17)15-7-3-2-4-8-15/h2-14H,1H3,(H,23,25) JUGUMYREZIKXCO-UHFFFAOYSA-N 50335008 5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2,4-triazol-3-amine::CHEMBL1649969 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 110 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335008&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994605 125085110 CHEMBL1649969 ZINC66100818 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919794 COc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H16FN3O/c1-26-21-24-23-20(25(21)19-10-6-5-9-18(19)22)17-13-11-16(12-14-17)15-7-3-2-4-8-15/h2-14H,1H3 JPAPRFILHOQFKN-UHFFFAOYSA-N 50335009 3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,2,4-triazole::CHEMBL1649970 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 990 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335009&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994689 125085111 CHEMBL1649970 ZINC66100819 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919795 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C22H18FN3/c1-2-21-24-25-22(26(21)20-11-7-6-10-19(20)23)18-14-12-17(13-15-18)16-8-4-3-5-9-16/h3-15H,2H2,1H3 ZQUPMAQZJIGBHA-UHFFFAOYSA-N 50335010 3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-triazole::CHEMBL1649974 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 230 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335010&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50993656 125085112 CHEMBL1649974 ZINC66101607 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919796 CC(C)c1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C23H20FN3/c1-16(2)22-25-26-23(27(22)21-11-7-6-10-20(21)24)19-14-12-18(13-15-19)17-8-4-3-5-9-17/h3-16H,1-2H3 XOGABADGFOGOCV-UHFFFAOYSA-N 50335011 3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-1,2,4-triazole::CHEMBL1649975 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 3300 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335011&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 22019234 125085113 CHEMBL1649975 ZINC01910267 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919807 COc1ccccc1-n1c(C)nnc1-c1ccc(cc1)-c1ccccc1 InChI=1S/C22H19N3O/c1-16-23-24-22(25(16)20-10-6-7-11-21(20)26-2)19-14-12-18(13-15-19)17-8-4-3-5-9-17/h3-15H,1-2H3 MHJPVIGLQHLUFI-UHFFFAOYSA-N 50114035 3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[1,2,4]triazole::CHEMBL87351 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1700 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114035&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 5034737 104008213 CHEMBL87351 ZINC00003106 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919808 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1 InChI=1S/C21H17N3/c1-16-22-23-21(24(16)20-10-6-3-7-11-20)19-14-12-18(13-15-19)17-8-4-2-5-9-17/h2-15H,1H3 LPJNRJXWXMNHIA-UHFFFAOYSA-N 50334998 3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazole::CHEMBL1649949 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1400 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334998&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 4391207 125085100 CHEMBL1649949 ZINC01512577 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919809 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H16FN3/c1-15-23-24-21(25(15)20-10-6-5-9-19(20)22)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14H,1H3 UDCNIDZIRCIMSB-UHFFFAOYSA-N 50335001 3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2,4-triazole::CHEMBL1649588 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 340 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335001&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994760 125085103 CHEMBL1649588 ZINC66103844 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919810 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1Cl InChI=1S/C21H16ClN3/c1-15-23-24-21(25(15)20-10-6-5-9-19(20)22)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14H,1H3 ILLRLZACVRCESL-UHFFFAOYSA-N 50335004 3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2,4-triazole::CHEMBL1649954 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 280 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335004&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994827 125085106 CHEMBL1649954 ZINC66101668 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919811 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C(F)(F)F InChI=1S/C22H16F3N3/c1-15-26-27-21(28(15)20-10-6-5-9-19(20)22(23,24)25)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14H,1H3 PBZZVMAQTLBVFE-UHFFFAOYSA-N 50335005 3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazole::CHEMBL1649955 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 600 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335005&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994828 125085107 CHEMBL1649955 ZINC66101670 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919812 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C#N InChI=1S/C22H16N4/c1-16-24-25-22(26(16)21-10-6-5-9-20(21)15-23)19-13-11-18(12-14-19)17-7-3-2-4-8-17/h2-14H,1H3 XAEBTKFUKICXCH-UHFFFAOYSA-N 50335006 2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl)benzonitrile::CHEMBL1649956 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 260 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335006&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994603 125085108 CHEMBL1649956 ZINC66101672 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919813 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1O InChI=1S/C21H17N3O/c1-15-22-23-21(24(15)19-9-5-6-10-20(19)25)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14,25H,1H3 NLIFUYBSDQHKCX-UHFFFAOYSA-N 50335007 2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-yl)phenol::CHEMBL1649957 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 680 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335007&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 10958392 125085109 CHEMBL1649957 ZINC13837282 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 50919814 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C InChI=1S/C22H19N3/c1-16-8-6-7-11-21(16)25-17(2)23-24-22(25)20-14-12-19(13-15-20)18-9-4-3-5-10-18/h3-15H,1-2H3 NAISOSWXEBSTRD-UHFFFAOYSA-N 50335012 3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2,4-triazole::CHEMBL1649958 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 780 ChEMBL 10.1021/jm101031u 10.7270/Q2H9965H 21141920 Kohara, A; Doihara, H; Saita, K; Aota, M Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335012&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 4423823 125085114 CHEMBL1649958 ZINC00236007 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075265 CCc1nnc(-c2ccc(nc2)-c2ccccc2)n1-c1cccc(C#N)c1C InChI=1S/C23H19N5/c1-3-22-26-27-23(28(22)21-11-7-10-18(14-24)16(21)2)19-12-13-20(25-15-19)17-8-5-4-6-9-17/h4-13,15H,3H2,1-2H3 DAAWESBJYLHFAS-UHFFFAOYSA-N 50439754 CHEMBL2419440 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >30000 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439754&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 9925334 175452071 CHEMBL2419440 ZINC34030881 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075267 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(c1C)[N+]([O-])=O InChI=1S/C23H20N4O2/c1-3-22-24-25-23(26(22)20-10-7-11-21(16(20)2)27(28)29)19-14-12-18(13-15-19)17-8-5-4-6-9-17/h4-15H,3H2,1-2H3 NMHFNABMCDUOFJ-UHFFFAOYSA-N 50439755 CHEMBL2419438 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 13000 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439755&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71763181 175452072 CHEMBL2419438 ZINC96283526 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075268 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(C#N)c1C InChI=1S/C24H20N4/c1-3-23-26-27-24(28(23)22-11-7-10-21(16-25)17(22)2)20-14-12-19(13-15-20)18-8-5-4-6-9-18/h4-15H,3H2,1-2H3 WZUXSBMNGNCRPQ-UHFFFAOYSA-N 50439731 CHEMBL2419437 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus >30000 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439731&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71763180 175452048 CHEMBL2419437 ZINC96283503 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075269 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(F)c1C InChI=1S/C23H20FN3/c1-3-22-25-26-23(27(22)21-11-7-10-20(24)16(21)2)19-14-12-18(13-15-19)17-8-5-4-6-9-17/h4-15H,3H2,1-2H3 URNUWJQXXIKCEO-UHFFFAOYSA-N 50439737 CHEMBL2419431 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 660 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439737&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762959 175452054 CHEMBL2419431 ZINC96283509 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075270 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(CO)c1C InChI=1S/C24H23N3O/c1-3-23-25-26-24(27(23)22-11-7-10-21(16-28)17(22)2)20-14-12-19(13-15-20)18-8-5-4-6-9-18/h4-15,28H,3,16H2,1-2H3 QOWBYARCGMTVPY-UHFFFAOYSA-N 50439740 CHEMBL2419428 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 3100 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439740&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762744 175452057 CHEMBL2419428 ZINC96283512 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075271 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(O)c1C InChI=1S/C23H21N3O/c1-3-22-24-25-23(26(22)20-10-7-11-21(27)16(20)2)19-14-12-18(13-15-19)17-8-5-4-6-9-17/h4-15,27H,3H2,1-2H3 WQVLNNMZFIKSFN-UHFFFAOYSA-N 50439741 CHEMBL2419427 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1300 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439741&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762742 175452058 CHEMBL2419427 ZINC96283513 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075272 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(N)c1C InChI=1S/C23H22N4/c1-3-22-25-26-23(27(22)21-11-7-10-20(24)16(21)2)19-14-12-18(13-15-19)17-8-5-4-6-9-17/h4-15H,3,24H2,1-2H3 FKNWKLYWGXANLI-UHFFFAOYSA-N 50439743 CHEMBL2419425 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 340 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439743&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762542 175452060 CHEMBL2419425 ZINC96283515 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075273 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(C)c1C InChI=1S/C24H23N3/c1-4-23-25-26-24(27(23)22-12-8-9-17(2)18(22)3)21-15-13-20(14-16-21)19-10-6-5-7-11-19/h5-16H,4H2,1-3H3 RVUWASDCOIJWGK-UHFFFAOYSA-N 50439744 CHEMBL2419424 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1200 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439744&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762541 175452061 CHEMBL2419424 ZINC96283516 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075274 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C InChI=1S/C23H21N3/c1-3-22-24-25-23(26(22)21-12-8-7-9-17(21)2)20-15-13-19(14-16-20)18-10-5-4-6-11-18/h4-16H,3H2,1-2H3 CNJJGPFTJIJTFI-UHFFFAOYSA-N 50439745 CHEMBL2419423 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 700 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439745&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762540 175452062 CHEMBL2419423 ZINC96283517 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075275 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc2cnccc12 InChI=1S/C25H20N4/c1-2-24-27-28-25(20-13-11-19(12-14-20)18-7-4-3-5-8-18)29(24)23-10-6-9-21-17-26-16-15-22(21)23/h3-17H,2H2,1H3 WNFUGBCAFJJYPS-UHFFFAOYSA-N 50360093 CHEMBL1928737 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 14000 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360093&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 22019226 136964155 CHEMBL1928737 ZINC82154637 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075276 CCc1nnc(-c2ccc(cn2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H17FN4/c1-2-20-24-25-21(26(20)19-11-7-6-10-17(19)22)18-13-12-16(14-23-18)15-8-4-3-5-9-15/h3-14H,2H2,1H3 KNGHOEPRLUNXLI-UHFFFAOYSA-N 50439749 CHEMBL2417571 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 890 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439749&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762328 175452066 CHEMBL2417571 ZINC96283521 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075277 CCc1nnc(-c2ccc(nc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H17FN4/c1-2-20-24-25-21(26(20)19-11-7-6-10-17(19)22)16-12-13-18(23-14-16)15-8-4-3-5-9-15/h3-14H,2H2,1H3 PNFIZBYDSLBYNC-UHFFFAOYSA-N 50439750 CHEMBL2419441 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 790 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439750&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762327 175452067 CHEMBL2419441 ZINC96283522 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075278 Cc1nnc(-c2ccc(cc2)-c2ccccn2)n1-c1ccccc1F InChI=1S/C20H15FN4/c1-14-23-24-20(25(14)19-8-3-2-6-17(19)21)16-11-9-15(10-12-16)18-7-4-5-13-22-18/h2-13H,1H3 WRYCGINDUVPELG-UHFFFAOYSA-N 50439751 CHEMBL2419444 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 1600 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439751&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 71762326 175452068 CHEMBL2419444 ZINC96283523 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075279 CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C22H18FN3/c1-2-21-24-25-22(26(21)20-11-7-6-10-19(20)23)18-14-12-17(13-15-18)16-8-4-3-5-9-16/h3-15H,2H2,1H3 ZQUPMAQZJIGBHA-UHFFFAOYSA-N 50335010 3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-triazole::CHEMBL1649974 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 230 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335010&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50993656 125085112 CHEMBL1649974 ZINC66101607 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3 51075280 Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1F InChI=1S/C21H16FN3/c1-15-23-24-21(25(15)20-10-6-5-9-19(20)22)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-14H,1H3 UDCNIDZIRCIMSB-UHFFFAOYSA-N 50335001 3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2,4-triazole::CHEMBL1649588 Sodium- and chloride-dependent glycine transporter 2 Rattus norvegicus 340 ChEMBL 10.1021/jm400383w 10.7270/Q2D79CVX 23837744 Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001604&target=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335001&enzyme=Sodium-+and+chloride-dependent+glycine+transporter+2&column=ki&startPg=0&Increment=50&submit=Search 50994760 125085103 CHEMBL1649588 ZINC66103844 1 MDCSAPKEMNKPPTNILEATVPGHRDSPRAPRTSPEQDLPAAAPAAAVQPPRVPRSASTGAQTFQSADARACEAQRPGVGFCKLSSPQAQATSAALRDLSEGHSAQANPPSGAAGAGNALHCKIPALRGPEEDENVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Sodium- and chloride-dependent glycine transporter 2 SC6A5_RAT P58295 F1LNM6 Q6QDB3